Ariel Ruiz i Altaba
|University of Geneva, Geneva, Switzerland|
Area:"sonic hedgehog, cancer, stem cells"
Google:"Ariel Ruiz i Altaba"
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|Melotti A, Mas C, Kuciak M, et al. (2014) The river blindness drug Ivermectin and related macrocyclic lactones inhibit WNT-TCF pathway responses in human cancer. Embo Molecular Medicine. 6: 1263-78|
|Duquet A, Melotti A, Mishra S, et al. (2014) A novel genome-wide in vivo screen for metastatic suppressors in human colon cancer identifies the positive WNT-TCF pathway modulators TMED3 and SOX12. Embo Molecular Medicine. 6: 882-901|
|Aberger F, Ruiz I Altaba A. (2014) Context-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapy. Seminars in Cell & Developmental Biology. 33: 93-104|
|Verbeni M, SÃ¡nchez O, Mollica E, et al. (2013) Morphogenetic action through flux-limited spreading. Physics of Life Reviews. 10: 457-75|
|Verbeni M, Sánchez O, Mollica E, et al. (2013) On flux-limited morphogenesis. Reply to the comments on "Morphogenetic action through flux-limited spreading". Physics of Life Reviews. 10: 495-497|
|Ruiz i Altaba A. (2011) Hedgehog signaling and the Gli code in stem cells, cancer, and metastases. Science Signaling. 4: pt9|
|Mas C, Ruiz i Altaba A. (2010) Small molecule modulation of HH-GLI signaling: current leads, trials and tribulations. Biochemical Pharmacology. 80: 712-23|
|Stecca B, Ruiz I Altaba A. (2010) Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals. Journal of Molecular Cell Biology. 2: 84-95|
|Varnat F, Zacchetti G, Ruiz i Altaba A. (2010) Hedgehog pathway activity is required for the lethality and intestinal phenotypes of mice with hyperactive Wnt signaling. Mechanisms of Development. 127: 73-81|
|Ruiz i Altaba A, Varnat F. (2010) On hedgehogs and human cancer Embo Molecular Medicine. 2: 386-387|