Ariel Ruiz i Altaba

Affiliations: 
Geneva University, Genève, Genève, Switzerland 
Area:
"sonic hedgehog, cancer, stem cells"
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"Ariel Ruiz i Altaba"
Mean distance: 106866
 
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Publications

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Melotti A, Mas C, Kuciak M, et al. (2014) The river blindness drug Ivermectin and related macrocyclic lactones inhibit WNT-TCF pathway responses in human cancer. Embo Molecular Medicine. 6: 1263-78
Duquet A, Melotti A, Mishra S, et al. (2014) A novel genome-wide in vivo screen for metastatic suppressors in human colon cancer identifies the positive WNT-TCF pathway modulators TMED3 and SOX12. Embo Molecular Medicine. 6: 882-901
Aberger F, Ruiz I Altaba A. (2014) Context-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapy. Seminars in Cell & Developmental Biology. 33: 93-104
Verbeni M, Sánchez O, Mollica E, et al. (2013) Morphogenetic action through flux-limited spreading. Physics of Life Reviews. 10: 457-75
Verbeni M, Sánchez O, Mollica E, et al. (2013) On flux-limited morphogenesis. Reply to the comments on "Morphogenetic action through flux-limited spreading". Physics of Life Reviews. 10: 495-497
Ruiz i Altaba A. (2011) Hedgehog signaling and the Gli code in stem cells, cancer, and metastases. Science Signaling. 4: pt9
Mas C, Ruiz i Altaba A. (2010) Small molecule modulation of HH-GLI signaling: current leads, trials and tribulations. Biochemical Pharmacology. 80: 712-23
Stecca B, Ruiz I Altaba A. (2010) Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals. Journal of Molecular Cell Biology. 2: 84-95
Varnat F, Zacchetti G, Ruiz i Altaba A. (2010) Hedgehog pathway activity is required for the lethality and intestinal phenotypes of mice with hyperactive Wnt signaling. Mechanisms of Development. 127: 73-81
Ruiz i Altaba A, Varnat F. (2010) On hedgehogs and human cancer Embo Molecular Medicine. 2: 386-387
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