Akira Nakai

1991-1993 Biochemistry Yamaguchi University Graduate School of Medicine 
"Akira Nakai"
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Kose S, Imai K, Watanabe A, et al. (2022) Lack of Hikeshi activates HSF1 activity under normal conditions and disturbs the heat-shock response. Life Science Alliance. 5
Srivastava P, Takii R, Okada M, et al. (2021) MED12 interacts with the heat shock transcription factor HSF1 and recruits CDK8 to promote the heat shock response in mammalian cells. Febs Letters
Katiyar A, Fujimoto M, Tan K, et al. (2020) HSF1 is required for induction of mitochondrial chaperones during the mitochondrial unfolded protein response. Febs Open Bio
Takii R, Fujimoto M, Matsumoto M, et al. (2019) The pericentromeric protein shugoshin 2 cooperates with HSF1 in heat shock response and RNA Pol II recruitment. The Embo Journal. e102566
Shao J, Han B, Cao P, et al. (2019) HSF1 phosphorylation by cyclosporin A confers hyperthermia sensitivity through suppression of HSP expression. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms
Taufiq F, Maharani N, Li P, et al. (2019) Uric Acid-Induced Enhancements of Kv1.5 Protein Expression and Channel Activity via the Akt-HSF1-Hsp70 Pathway in HL-1 Atrial Myocytes. Circulation Journal : Official Journal of the Japanese Circulation Society
Fujimoto M, Takii R, Katiyar A, et al. (2018) PARP1 promotes the human heat shock response by facilitating HSF1 binding to DNA. Molecular and Cellular Biology
Oda T, Sekimoto T, Kurashima K, et al. (2018) Acute HSF1 depletion induces cellular senescence through the MDM2-p53-p21 pathway in human diploid fibroblasts. Journal of Cell Science. 131
Fujimoto M, Takii R, Takaki E, et al. (2017) The HSF1-PARP13-PARP1 complex facilitates DNA repair and promotes mammary tumorigenesis. Nature Communications. 8: 1638
Takii R, Fujimoto M, Matsuura Y, et al. (2017) HSF1 and HSF3 cooperatively regulate the heat shock response in lizards. Plos One. 12: e0180776
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