Akira Nakai
Affiliations: | 1991-1993 | Biochemistry | Yamaguchi University Graduate School of Medicine |
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Parents
Sign in to add mentor| Richard I. Morimoto | post-doc | 1991-1993 | Yamaguchi University Graduate School of Medicine |
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Publications
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| Fujimoto M, Takii R, Nakai A. (2023) Regulation of HSF1 transcriptional complexes under proteotoxic stress: Mechanisms of heat shock gene transcription involve the stress-induced HSF1 complex formation, changes in chromatin states, and formation of phase-separated condensates. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e2300036 |
| Okada M, Fujimoto M, Srivastava P, et al. (2023) The Mediator subunit MED12 promotes formation of HSF1 condensates on heat shock response element arrays in heat-shocked cells. Febs Letters |
| Kose S, Imai K, Watanabe A, et al. (2022) Lack of Hikeshi activates HSF1 activity under normal conditions and disturbs the heat-shock response. Life Science Alliance. 5 |
| Srivastava P, Takii R, Okada M, et al. (2021) MED12 interacts with the heat shock transcription factor HSF1 and recruits CDK8 to promote the heat shock response in mammalian cells. Febs Letters |
| Katiyar A, Fujimoto M, Tan K, et al. (2020) HSF1 is required for induction of mitochondrial chaperones during the mitochondrial unfolded protein response. Febs Open Bio |
| Takii R, Fujimoto M, Matsumoto M, et al. (2019) The pericentromeric protein shugoshin 2 cooperates with HSF1 in heat shock response and RNA Pol II recruitment. The Embo Journal. e102566 |
| Shao J, Han B, Cao P, et al. (2019) HSF1 phosphorylation by cyclosporin A confers hyperthermia sensitivity through suppression of HSP expression. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms |
| Taufiq F, Maharani N, Li P, et al. (2019) Uric Acid-Induced Enhancements of Kv1.5 Protein Expression and Channel Activity via the Akt-HSF1-Hsp70 Pathway in HL-1 Atrial Myocytes. Circulation Journal : Official Journal of the Japanese Circulation Society |
| Fujimoto M, Takii R, Katiyar A, et al. (2018) PARP1 promotes the human heat shock response by facilitating HSF1 binding to DNA. Molecular and Cellular Biology |
| Oda T, Sekimoto T, Kurashima K, et al. (2018) Acute HSF1 depletion induces cellular senescence through the MDM2-p53-p21 pathway in human diploid fibroblasts. Journal of Cell Science. 131 |