Nicholas J Queen

Affiliations: 
The Ohio State Universtiy 
Area:
gene therapy, neuroscience, AAV
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"Nicholas Queen"
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Lei Cao research assistant 2015-2019 Ohio State
Lei Cao grad student 2019- Ohio State
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Publications

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Queen NJ, Deng H, Huang W, et al. (2021) Environmental enrichment mitigates age-related metabolic decline and Lewis lung carcinoma growth in aged female mice. Cancer Prevention Research (Philadelphia, Pa.)
Bergin SM, Xiao R, Huang W, et al. (2021) Environmental activation of a hypothalamic BDNF-adipocyte IL-15 axis regulates adipose- natural killer cells. Brain, Behavior, and Immunity
Cao L, Ali S, Queen NJ. (2021) Hypothalamic gene transfer of BDNF promotes healthy aging. Vitamins and Hormones. 115: 39-66
Queen NJ, Bates R, Huang W, et al. (2021) Visceral adipose tissue-directed FGF21 gene therapy improves metabolic and immune health in BTBR mice. Molecular Therapy. Methods & Clinical Development. 20: 409-422
Mansour AG, Xiao R, Bergin SM, et al. (2020) Enriched environment enhances NK cell maturation through hypothalamic BDNF in male mice. European Journal of Immunology
Hassan QN, Queen NJ, Cao L. (2020) Regulation of aging and cancer by enhanced environmental activation of a hypothalamic-sympathoneural-adipocyte axis. Translational Cancer Research. 9: 5687-5699
Queen NJ, Hassan QN, Cao L. (2020) Improvements to Healthspan Through Environmental Enrichment and Lifestyle Interventions: Where Are We Now? Frontiers in Neuroscience. 14: 605
Ali S, Mansour AG, Huang W, et al. (2020) CSF1R inhibitor PLX5622 and environmental enrichment additively improve metabolic outcomes in middle-aged female mice. Aging. 12
Huang W, Queen NJ, McMurphy TB, et al. (2019) Adipose PTEN regulates adult adipose tissue homeostasis and redistribution via a PTEN-leptin-sympathetic loop. Molecular Metabolism. 30: 48-60
Queen NJ, Boardman AA, Patel RS, et al. (2019) Environmental enrichment improves metabolic and behavioral health in the BTBR mouse model of autism. Psychoneuroendocrinology. 111: 104476
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