Jorge E Contreras, PhD

2020- Physiology & Membrane Biology University of California, Davis, Davis, CA 
Large Pore Channels, Connexins, Pannexin, Gap Junction Channels, Connexin Hemichannels, Cardiac Physiology, Arrhythmias
"Jorge E Contreras PhD"
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Jiang W, Lin YC, Botello-Smith W, et al. (2021) Free energy and kinetics of cAMP permeation through connexin26 via applied voltage and milestoning. Biophysical Journal
Gaete PS, Contreras JE. (2021) A method for assessing ionic and molecular permeation in connexin hemichannels. Methods in Enzymology. 654: 271-293
Seo JH, Dalal MS, Contreras JE. (2021) Pannexin-1 Channels as Mediators of Neuroinflammation. International Journal of Molecular Sciences. 22
Narahari AK, Kreutzberger AJB, Gaete PS, et al. (2021) ATP and large signaling metabolites flux through caspase-activated Pannexin 1 channels. Elife. 10
Gaete PS, Lillo MA, López W, et al. (2020) A novel voltage-clamp/dye uptake assay reveals saturable transport of molecules through CALHM1 and connexin channels. The Journal of General Physiology. 152
Naulin PA, Lozano B, Fuentes C, et al. (2020) Polydisperse molecular architecture of connexin 26/30 heteromeric hemichannels revealed by AFM imaging. The Journal of Biological Chemistry
Seo JH, Dalal MS, Calderon F, et al. (2020) Myeloid Pannexin-1 mediates acute leukocyte infiltration and leads to worse outcomes after brain trauma. Journal of Neuroinflammation. 17: 245
Gaete PS, Contreras JE. (2020) Taking a close look at a large-pore channel. Elife. 9
Gaete PS, Contreras JE. (2019) Uncoupled permeation through large-pore channels: ions and molecules don't always ride together. The Journal of Physiology
Valdez Capuccino JM, Chatterjee P, García IE, et al. (2018) The connexin26 human mutation N14K disrupts cytosolic intersubunit interactions and promotes channel opening. The Journal of General Physiology
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