Cecilia M Borghese

Affiliations: 
University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Ligand-gated ion channels; voltage-gated potassium channels
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"Cecilia Borghese"
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Publications

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York JM, Borghese CM, George AA, et al. (2023) A potential cost of evolving epibatidine resistance in poison frogs. Biorxiv : the Preprint Server For Biology
Arias HR, Borghese CM, Germann AL, et al. (2022) (+)-Catharanthine potentiates the GABA receptor by binding to a transmembrane site at the β(+)/α(-) interface near the TM2-TM3 loop. Biochemical Pharmacology. 199: 114993
Borghese CM, Wang HL, McHardy SF, et al. (2021) Modulation of α1β3γ2 GABA receptors expressed in oocytes using a propofol photoswitch tethered to the transmembrane helix. Proceedings of the National Academy of Sciences of the United States of America. 118
Blednov YA, Borghese CM, Dugan MP, et al. (2020) Apremilast regulates acute effects of ethanol and other GABAergic drugs via protein kinase A-dependent signaling. Neuropharmacology. 108220
Tarvin RD, Borghese CM, Sachs W, et al. (2017) Interacting amino acid replacements allow poison frogs to evolve epibatidine resistance. Science (New York, N.Y.). 357: 1261-1266
Borghese CM, Herman M, Snell LD, et al. (2017) Novel Molecule Exhibiting Selective Affinity for GABAA Receptor Subtypes. Scientific Reports. 7: 6230
Blednov YA, Borghese CM, Ruiz CI, et al. (2017) Mutation of the inhibitory ethanol site in GABAA ρ1 receptors promotes tolerance to ethanol-induced motor incoordination. Neuropharmacology
Borghese CM, Ruiz CI, Lee US, et al. (2015) Identification of an Inhibitory Alcohol Binding Site in GABAA ρ1 Receptors. Acs Chemical Neuroscience
Blednov YA, Benavidez JM, Black M, et al. (2014) GABAA receptors containing ρ1 subunits contribute to in vivo effects of ethanol in mice. Plos One. 9: e85525
Borghese CM, Hicks JA, Lapid DJ, et al. (2014) GABA(A) receptor transmembrane amino acids are critical for alcohol action: disulfide cross-linking and alkyl methanethiosulfonate labeling reveal relative location of binding sites. Journal of Neurochemistry. 128: 363-75
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