Juan Valcárcel, PhD
Affiliations: | 2004- | Genome Biology | Centre for Genomic Regulation (CRG), Spain |
Area:
Alternative Splicing, RNAGoogle:
"Juan Valcárcel"Mean distance: (not calculated yet)
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Sign in to add trainee| Niccolò Arecco | post-doc | 2023- | Centre for Genomic Regulation (CRG) (Cell Biology Tree) |
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Publications
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| Guerra-Moreno Á, Valcárcel J. (2023) AI-assisted proofreading of RNA splicing. Genes & Development. 37: 945-947 |
| López-Oreja I, Gohr A, Playa-Albinyana H, et al. (2023) mutation-mediated sensitization to H3B-8800 splicing inhibitor in chronic lymphocytic leukemia. Life Science Alliance. 6 |
| Juan-Mateu J, Bajew S, Miret-Cuesta M, et al. (2023) Pancreatic microexons regulate islet function and glucose homeostasis. Nature Metabolism |
| Rogalska ME, Vivori C, Valcárcel J. (2022) Regulation of pre-mRNA splicing: roles in physiology and disease, and therapeutic prospects. Nature Reviews. Genetics. 24: 251-269 |
| Baeza-Centurion P, Minana B, Valcarcel J, et al. (2020) Mutations primarily alter the inclusion of alternatively spliced exons. Elife. 9 |
| Keiper S, Papasaikas P, Will CL, et al. (2019) Smu1 and RED are required for activation of spliceosomal B complexes assembled on short introns. Nature Communications. 10: 3639 |
| Torres-Méndez A, Bonnal S, Marquez Y, et al. (2019) A novel protein domain in an ancestral splicing factor drove the evolution of neural microexons. Nature Ecology & Evolution |
| Vigevani L, Gohr A, Webb T, et al. (2017) Molecular basis of differential 3' splice site sensitivity to anti-tumor drugs targeting U2 snRNP. Nature Communications. 8: 2100 |
| Sebestyén E, Singh B, Miñana B, et al. (2016) Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks. Genome Research |
| Julien P, Miñana B, Baeza-Centurion P, et al. (2016) The complete local genotype-phenotype landscape for the alternative splicing of a human exon. Nature Communications. 7: 11558 |