Craig W. Lindsley, Ph.D.

Affiliations: 
2006- Pharmacology Vanderbilt University, Nashville, TN 
Website:
http://www.mc.vanderbilt.edu/labs/lindsley/lindsleycw.html
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Emily Jeanne Lilla research assistant 2017- Vanderbilt
Pedro Manuel Garcia-Barrantes grad student Vanderbilt
Evan P. Lebois grad student Vanderbilt (Neurotree)
Kellie D. Nance grad student Vanderbilt
Jeanette L Bertron grad student 2016- Vanderbilt
Richard Nathan Daniels grad student 2010 Vanderbilt
J. Phillip Kennedy grad student 2010 Vanderbilt
Olugbeminiyi Fadeyi grad student 2011 Vanderbilt
Leslie N. Aldrich grad student 2012 Vanderbilt
Sydney Lear Stoops grad student 2012 Vanderbilt
Michael L. Schulte grad student 2009-2013 Vanderbilt
Robert Raymond Lavieri grad student 2014 Vanderbilt
Timothy J. Senter grad student 2010-2015 Vanderbilt
Cody J. Wenthur grad student 2011-2015 Vanderbilt
Caitlin N Kent grad student 2019-2020
Kayla J. Temple post-doc 2014- Vanderbilt
Aaron T Garrison post-doc 2018-2019 Vanderbilt
Melissa Alara Korkmaz-Vaisys post-doc 2020-2021 Vanderbilt
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Publications

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Childress ES, Capstick RA, Crocker KE, et al. (2024) Discovery of 4-(5-Membered)Heteroarylether-6-methylpicolinamide Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5. Acs Medicinal Chemistry Letters. 15: 2210-2219
Engers JL, Baker LA, Chang S, et al. (2024) Discovery of VU6016235: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM). Acs Chemical Neuroscience. 15: 3744-54
Capstick RA, Bollinger SR, Engers JL, et al. (2024) Discovery of VU6008677: A Structurally Distinct Tricyclic M Positive Allosteric Modulator with Improved CYP450 Profile. Acs Medicinal Chemistry Letters. 15: 1358-1366
Dwomoh L, Rossi M, Scarpa M, et al. (2022) M muscarinic receptor activation reduces the molecular pathology and slows the progression of prion-mediated neurodegenerative disease. Science Signaling. 15: eabm3720
Luessen DJ, Gallinger IM, Ferranti AS, et al. (2022) mGlu-mediated restoration of prefrontal cortex inhibitory signaling reverses social and cognitive deficits in an NMDA hypofunction model in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Garrison AT, Orsi DL, Capstick RA, et al. (2022) Development of : A Potent, Highly Selective, and Systemically Active Orthosteric Antagonist of the M Muscarinic Acetylcholine Receptor for the Treatment of Opioid Use Disorder. Journal of Medicinal Chemistry
McClenahan SJ, Kent C, Kharade S, et al. (2022) . Molecular Pharmacology
Bertron JL, Duvernay MT, Mitchell SG, et al. (2021) Discovery and Optimization of a Novel Series of Competitive and Central Nervous System-Penetrant Protease-Activated Receptor 4 (PAR4) Inhibitors. Acs Chemical Neuroscience
Long MF, Capstick RA, Spearing PK, et al. (2021) Development of structurally distinct tricyclic M positive allosteric modulator (PAM) chemotypes - Part 2. Bioorganic & Medicinal Chemistry Letters. 128416
Yamada Y, Gilliland K, Xiang Z, et al. (2021) Positive allosteric modulators (PAMs) of the group II metabotropic glutamate receptors: Design, synthesis, and evaluation as ex-vivo tool compounds. Bioorganic & Medicinal Chemistry Letters. 128342
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