Dmitri R. Davydov

Affiliations: 
Chemistry  
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Ponraj K, Gaither KA, Kumar Singh D, et al. (2024) Non-additivity of the functional properties of individual P450 species and its manifestation in the effects of alcohol consumption on the metabolism of ketamine and amitriptyline. Biochemical Pharmacology. 230: 116569
Gaither KA, Singh DK, Yue G, et al. (2024) Effects of alcohol consumption and tobacco smoking on the composition of the ensemble of drug metabolizing enzymes and transporters in human liver. Biorxiv : the Preprint Server For Biology
Singh DK, Ahire D, Davydov DR, et al. (2024) . Drug Metabolism and Disposition: the Biological Fate of Chemicals
Davydova NY, Hutner DA, Gaither KA, et al. (2023) High-Throughput Assay of Cytochrome P450-Dependent Drug Demethylation Reactions and Its Use to Re-Evaluate the Pathways of Ketamine Metabolism. Biology. 12
Davydov DR, Dangi B, Yue G, et al. (2022) Exploring the Interactome of Cytochrome P450 2E1 in Human Liver Microsomes with Chemical Crosslinking Mass Spectrometry. Biomolecules. 12
Davydov DR, Prasad B. (2021) Assembling the P450 puzzle: on the sources of nonadditivity in drug metabolism. Trends in Pharmacological Sciences. 42: 988-997
Dangi B, Davydova NY, Maldonado MA, et al. (2021) Probing functional interactions between cytochromes P450 with principal component analysis of substrate saturation profiles and targeted proteomics. Archives of Biochemistry and Biophysics. 708: 108937
Dangi B, Davydova NY, Maldonado MA, et al. (2020) Effects of alcohol-induced increase in CYP2E1 content in human liver microsomes on the activity and cooperativity of CYP3A4. Archives of Biochemistry and Biophysics. 698: 108677
Dangi B, Davydova NY, Vavilov NE, et al. (2020) Nonadditivity in human microsomal drug metabolism revealed in a study with coumarin 152, a polyspecific cytochrome P450 substrate. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 50: 1393-1405
Davydova NY, Dangi B, Maldonado MA, et al. (2020) Toward a systems approach to cytochrome P450 ensemble: interactions of CYP2E1 with other P450 species and their impact on CYP1A2. The Biochemical Journal. 476: 3661-3685
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