| Year |
Citation |
Score |
| 2024 |
Ponraj K, Gaither KA, Kumar Singh D, Davydova N, Zhao M, Luo S, Lazarus P, Prasad B, Davydov DR. Non-additivity of the functional properties of individual P450 species and its manifestation in the effects of alcohol consumption on the metabolism of ketamine and amitriptyline. Biochemical Pharmacology. 230: 116569. PMID 39393643 DOI: 10.1016/j.bcp.2024.116569 |
0.483 |
|
| 2024 |
Gaither KA, Singh DK, Yue G, Trudeau J, Ponraj K, Davydova NY, Lazarus P, Davydov DR, Prasad B. Effects of alcohol consumption and tobacco smoking on the composition of the ensemble of drug metabolizing enzymes and transporters in human liver. Biorxiv : the Preprint Server For Biology. PMID 38798409 DOI: 10.1101/2024.05.14.594255 |
0.481 |
|
| 2024 |
Singh DK, Ahire D, Davydov DR, Prasad B. . Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 38641346 DOI: 10.1124/dmd.124.001477 |
0.399 |
|
| 2023 |
Davydova NY, Hutner DA, Gaither KA, Singh DK, Prasad B, Davydov DR. High-Throughput Assay of Cytochrome P450-Dependent Drug Demethylation Reactions and Its Use to Re-Evaluate the Pathways of Ketamine Metabolism. Biology. 12. PMID 37626940 DOI: 10.3390/biology12081055 |
0.501 |
|
| 2022 |
Davydov DR, Dangi B, Yue G, Ahire DS, Prasad B, Zgoda VG. Exploring the Interactome of Cytochrome P450 2E1 in Human Liver Microsomes with Chemical Crosslinking Mass Spectrometry. Biomolecules. 12. PMID 35204686 DOI: 10.3390/biom12020185 |
0.481 |
|
| 2021 |
Davydov DR, Prasad B. Assembling the P450 puzzle: on the sources of nonadditivity in drug metabolism. Trends in Pharmacological Sciences. 42: 988-997. PMID 34602306 DOI: 10.1016/j.tips.2021.09.004 |
0.467 |
|
| 2021 |
Dangi B, Davydova NY, Maldonado MA, Ahire D, Prasad B, Davydov DR. Probing functional interactions between cytochromes P450 with principal component analysis of substrate saturation profiles and targeted proteomics. Archives of Biochemistry and Biophysics. 708: 108937. PMID 34058150 DOI: 10.1016/j.abb.2021.108937 |
0.491 |
|
| 2020 |
Dangi B, Davydova NY, Maldonado MA, Abbasi A, Vavilov NE, Zgoda VG, Davydov DR. Effects of alcohol-induced increase in CYP2E1 content in human liver microsomes on the activity and cooperativity of CYP3A4. Archives of Biochemistry and Biophysics. 698: 108677. PMID 33197431 DOI: 10.1016/j.abb.2020.108677 |
0.71 |
|
| 2020 |
Dangi B, Davydova NY, Vavilov NE, Zgoda VG, Davydov DR. Nonadditivity in human microsomal drug metabolism revealed in a study with coumarin 152, a polyspecific cytochrome P450 substrate. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 50: 1393-1405. PMID 32662751 DOI: 10.1080/00498254.2020.1775913 |
0.468 |
|
| 2020 |
Davydova NY, Dangi B, Maldonado MA, Vavilov NE, Zgoda VG, Davydov DR. Toward a systems approach to cytochrome P450 ensemble: interactions of CYP2E1 with other P450 species and their impact on CYP1A2. The Biochemical Journal. 476: 3661-3685. PMID 31750875 DOI: 10.1042/BCJ20190532 |
0.479 |
|
| 2018 |
Rodgers JT, Davydova NY, Paragas EM, Jones JP, Davydov DR. Kinetic mechanism of time-dependent inhibition of CYP2D6 by 3,4-methylenedioxymethamphetamine (MDMA): functional heterogeneity of the enzyme and the reversibility of its inactivation. Biochemical Pharmacology. PMID 30114388 DOI: 10.1016/j.bcp.2018.08.010 |
0.35 |
|
| 2017 |
Davydov DR, Davydova NY, Rodgers JT, Rushmore TH, Jones JP. Towards a systems approach to human cytochrome P450 ensemble: Interactions between CYP2D6 and CYP2E1 and their functional consequences. The Biochemical Journal. PMID 28904078 DOI: 10.1042/BCJ20170543 |
0.508 |
|
| 2015 |
Davydov DR, Davydova NY, Sineva EV, Halpert JR. Interactions among cytochromes P450 in microsomal membranes: Oligomerization of cytochromes P4503A4,3A5, and 2E1 and its functional consequences Journal of Biological Chemistry. 290: 3850-3868. PMID 25533469 DOI: 10.1074/jbc.M114.615443 |
0.373 |
|
| 2013 |
Davydov DR, Davydova NY, Sineva EV, Kufareva I, Halpert JR. Pivotal role of P450-P450 interactions in CYP3A4 allostery: The case of α-naphthoflavone Biochemical Journal. 453: 219-230. PMID 23651100 DOI: 10.1042/BJ20130398 |
0.354 |
|
| 2013 |
Davydov DR, Sineva EV, Davydova NY, Bartlett DH, Halpert JR. CYP261 enzymes from deep sea bacteria: a clue to conformational heterogeneity in cytochromes P450. Biotechnology and Applied Biochemistry. 60: 30-40. PMID 23586990 DOI: 10.1002/Bab.1083 |
0.315 |
|
| 2010 |
Davydov DR, Sineva EV, Sistla S, Davydova NY, Frank DJ, Sligar SG, Halpert JR. Electron transfer in the complex of membrane-bound human cytochrome P450 3A4 with the flavin domain of P450BM-3: the effect of oligomerization of the heme protein and intermittent modulation of the spin equilibrium. Biochimica Et Biophysica Acta. 1797: 378-90. PMID 20026040 DOI: 10.1016/J.Bbabio.2009.12.008 |
0.317 |
|
| 2005 |
Davydov DR, Fernando H, Baas BJ, Sligar SG, Halpert JR. Kinetics of dithionite-dependent reduction of cytochrome P450 3A4: heterogeneity of the enzyme caused by its oligomerization. Biochemistry. 44: 13902-13. PMID 16229479 DOI: 10.1021/Bi0509346 |
0.311 |
|
| 2003 |
Davydov DR, Halpert JR, Renaud JP, Hui Bon Hoa G. Conformational heterogeneity of cytochrome P450 3A4 revealed by high pressure spectroscopy. Biochemical and Biophysical Research Communications. 312: 121-30. PMID 14630029 DOI: 10.1016/J.Bbrc.2003.09.247 |
0.301 |
|
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