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Gustaaf de Ridder

Affiliations: 
2010 Pathology Duke University, Durham, NC 
Area:
protein chemistry
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"Gustaaf de Ridder"
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Salvatore V. Pizzo grad student 2010 Duke
 (Cell-Surface GRP78 and its Antibodies: Pathologic and Therapeutic Roles in Cancer.)

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Publications

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Jensen BC, Bultman SJ, Holley D, et al. (2017) Upregulation of autophagy genes and the unfolded protein response in human heart failure. International Journal of Clinical and Experimental Medicine. 10: 1051-1058
de Ridder GG, Lundblad RL, Pizzo SV. (2015) Actions of Thrombin in the Interstitium. Journal of Thrombosis and Haemostasis : Jth
Li S, Payne S, Wang F, et al. (2015) Nuclear basic fibroblast growth factor regulates triple-negative breast cancer chemo-resistance. Breast Cancer Research : Bcr. 17: 91
Gonzalez-Gronow M, Gomez CF, de Ridder GG, et al. (2014) Binding of tissue-type plasminogen activator to the glucose-regulated protein 78 (GRP78) modulates plasminogen activation and promotes human neuroblastoma cell proliferation in vitro. The Journal of Biological Chemistry. 289: 25166-76
Maddala R, Nagendran T, de Ridder GG, et al. (2013) L-type calcium channels play a critical role in maintaining lens transparency by regulating phosphorylation of aquaporin-0 and myosin light chain and expression of connexins. Plos One. 8: e64676
Ray R, de Ridder GG, Eu JP, et al. (2012) The Escherichia coli subtilase cytotoxin A subunit specifically cleaves cell-surface GRP78 protein and abolishes COOH-terminal-dependent signaling. The Journal of Biological Chemistry. 287: 32755-69
de Ridder GG, Ray R, Pizzo SV. (2012) A murine monoclonal antibody directed against the carboxyl-terminal domain of GRP78 suppresses melanoma growth in mice. Melanoma Research. 22: 225-35
Selim MA, Burchette JL, Bowers EV, et al. (2011) Changes in oligosaccharide chains of autoantibodies to GRP78 expressed during progression of malignant melanoma stimulate melanoma cell growth and survival. Melanoma Research. 21: 323-34
de Ridder G, Ray R, Misra UK, et al. (2011) Modulation of the unfolded protein response by GRP78 in prostate cancer. Methods in Enzymology. 489: 245-57
de Ridder GG, Gonzalez-Gronow M, Ray R, et al. (2011) Autoantibodies against cell surface GRP78 promote tumor growth in a murine model of melanoma. Melanoma Research. 21: 35-43
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