| Year |
Citation |
Score |
| 2020 |
Chen KG, Duran GE, Mogul MJ, Wang YC, Ross KL, Jaffrézou JP, Huff LM, Johnson KR, Fojo T, Lacayo NJ, Sikic BI. Genomic stability at the coding regions of the multidrug transporter gene : insights into the development of alternative drug resistance mechanisms in human leukemia cells. Cancer Drug Resistance (Alhambra, Calif.). 3: 959-979. PMID 34541464 DOI: 10.20517/cdr.2020.51 |
0.605 |
|
| 2006 |
Ségui B, Andrieu-Abadie N, Jaffrézou JP, Benoist H, Levade T. Sphingolipids as modulators of cancer cell death: potential therapeutic targets. Biochimica Et Biophysica Acta. 1758: 2104-20. PMID 16925980 DOI: 10.1016/J.Bbamem.2006.05.024 |
0.436 |
|
| 2004 |
Jaffrezou JP, Laurent G. Ceramide : A New Target in Anticancer Research? Bulletin Du Cancer. 91: E133-61. PMID 15568227 |
0.305 |
|
| 2004 |
Dumontet C, Jaffrezou JP, Tsuchiya E, Duran GE, Chen G, Derry WB, Wilson L, Jordan MA, Sikic BI. Resistance to microtubule-targeted cytotoxins in a K562 leukemia cell variant associated with altered tubulin expression and polymerization. Bulletin Du Cancer. 91: E81-112. PMID 15568225 |
0.591 |
|
| 2004 |
Grazide S, Terrisse AD, Lerouge S, Laurent G, Jaffrézou JP. Cytoprotective effect of glucosylceramide synthase inhibition against daunorubicin-induced apoptosis in human leukemic cell lines. The Journal of Biological Chemistry. 279: 18256-61. PMID 14766899 DOI: 10.1074/Jbc.M314105200 |
0.505 |
|
| 2004 |
Jaffrézou J, Laurent G, Levade T. Ceramide in Regulation of Apoptosis Sub-Cellular Biochemistry. 36: 269-284. DOI: 10.1007/0-306-47931-1_14 |
0.456 |
|
| 2003 |
Bezombes C, Laurent G, Jaffrézou JP. Implication of raft microdomains in drug induced apoptosis. Current Medicinal Chemistry. Anti-Cancer Agents. 3: 263-70. PMID 12769772 DOI: 10.2174/1568011033482413 |
0.434 |
|
| 2003 |
Maestre N, Bezombes C, Plo I, Levade T, Lavelle F, Laurent G, Jaffrézou JP. Phosphatidylcholine-derived phosphatidic acid and diacylglycerol are involved in the signaling pathways activated by docetaxel. Journal of Experimental Therapeutics & Oncology. 3: 36-46. PMID 12724857 DOI: 10.1046/J.1359-4117.2003.01065.X |
0.338 |
|
| 2003 |
Mas VM, Hernandez H, Plo I, Bezombes C, Maestre N, Quillet-Mary A, Filomenko R, Demur C, Jaffrézou JP, Laurent G. Protein kinase Czeta mediated Raf-1/extracellular-regulated kinase activation by daunorubicin. Blood. 101: 1543-50. PMID 12406911 DOI: 10.1182/Blood-2002-05-1585 |
0.355 |
|
| 2002 |
Bezombes C, de Thonel A, Apostolou A, Louat T, Jaffrézou JP, Laurent G, Quillet-Mary A. Overexpression of protein kinase Czeta confers protection against antileukemic drugs by inhibiting the redox-dependent sphingomyelinase activation. Molecular Pharmacology. 62: 1446-55. PMID 12435813 DOI: 10.1124/Mol.62.6.1446 |
0.475 |
|
| 2002 |
Terrisse AD, Bezombes C, Lerouge S, Laurent G, Jaffrézou JP. Daunorubicin- and Ara-C-induced interphasic apoptosis of human type II leukemia cells is caspase-8-independent. Biochimica Et Biophysica Acta. 1584: 99-103. PMID 12385892 DOI: 10.1016/S1388-1981(02)00297-4 |
0.453 |
|
| 2002 |
Grazide S, Maestre N, Veldman RJ, Bezombes C, Maddens S, Levade T, Laurent G, Jaffrézou JP. Ara-C- and daunorubicin-induced recruitment of Lyn in sphingomyelinase-enriched membrane rafts. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1685-7. PMID 12206990 DOI: 10.1096/Fj.01-0794Fje |
0.395 |
|
| 2002 |
Lecompte MF, Laurent G, Jaffrézou JP. Sphingomyelin content conditions insertion of daunorubicin within phosphatidylcholine monolayers. Febs Letters. 525: 141-4. PMID 12163177 DOI: 10.1016/S0014-5793(02)03063-6 |
0.339 |
|
| 2002 |
Maddens S, Charruyer A, Plo I, Dubreuil P, Berger S, Salles B, Laurent G, Jaffrézou JP. Kit signaling inhibits the sphingomyelin-ceramide pathway through PLC gamma 1: implication in stem cell factor radioprotective effect. Blood. 100: 1294-301. PMID 12149210 |
0.361 |
|
| 2002 |
Jaffrézou JP, Laurent G, Levade T. Ceramide in regulation of apoptosis. Implication in multitoxicant resistance. Sub-Cellular Biochemistry. 36: 269-84. PMID 12037986 |
0.308 |
|
| 2002 |
Maddens S, Charruyer A, Plo I, Dubreuil P, Berger S, Salles B, Laurent G, Jaffrézou J. Kit signaling inhibits the sphingomyelin-ceramide pathway through PLCγ1: implication in stem cell factor radioprotective effect Blood. 100: 1294-1301. DOI: 10.1182/Blood.V100.4.1294.H81602001294_1294_1301 |
0.452 |
|
| 2001 |
Laurent G, Jaffrézou JP. Signaling pathways activated by daunorubicin. Blood. 98: 913-24. PMID 11493433 DOI: 10.1182/Blood.V98.4.913 |
0.37 |
|
| 2001 |
Bezombes C, Plo I, Mansat-De Mas V, Quillet-Mary A, Nègre-Salvayre A, Laurent G, Jaffrézou JP. Oxidative stress-induced activation of Lyn recruits sphingomyelinase and is requisite for its stimulation by Ara-C. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1583-5. PMID 11427493 DOI: 10.1096/Fj.00-0787Fje |
0.414 |
|
| 2001 |
Maestre N, Tritton TR, Laurent G, Jaffrézou JP. Cell surface-directed interaction of anthracyclines leads to cytotoxicity and nuclear factor kappaB activation but not apoptosis signaling. Cancer Research. 61: 2558-61. PMID 11289131 |
0.371 |
|
| 2001 |
Bezombes C, Ségui B, Cuvillier O, Bruno AP, Uro-Coste E, Gouazé V, Andrieu-Abadie N, Carpentier S, Laurent G, Salvayre R, Jaffrézou JP, Levade T. Lysosomal sphingomyelinase is not solicited for apoptosis signaling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 297-9. PMID 11156942 DOI: 10.1096/Fj.00-0466Fje |
0.415 |
|
| 2001 |
Jaffrézou JP, Bruno AP, Moisand A, Levade T, Laurent G. Activation of a nuclear sphingomyelinase in radiation-induced apoptosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 123-133. PMID 11149900 DOI: 10.1096/Fj.00-0305Com |
0.381 |
|
| 2000 |
Ségui B, Bezombes C, Uro-Coste E, Medin JA, Andrieu-Abadie N, Augé N, Brouchet A, Laurent G, Salvayre R, Jaffrézou JP, Levade T. Stress-induced apoptosis is not mediated by endolysosomal ceramide. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 14: 36-47. PMID 10627278 DOI: 10.1096/Fasebj.14.1.36 |
0.4 |
|
| 1999 |
Levade T, Andrieu-Abadie N, Ségui B, Augé N, Chatelut M, Jaffrézou JP, Salvayre R. Sphingomyelin-degrading pathways in human cells role in cell signalling. Chemistry and Physics of Lipids. 102: 167-78. PMID 11001571 DOI: 10.1016/S0009-3084(99)00085-7 |
0.389 |
|
| 1999 |
Jaffrézou JP, Laurent G. [Role of lipid second messengers involved in the response of leukemic cells to anticancer drugs]. Journal De La SociéTé De Biologie. 193: 429-37. PMID 10689626 |
0.369 |
|
| 1999 |
Delpy E, Hatem SN, Andrieu N, de Vaumas C, Henaff M, Rücker-Martin C, Jaffrézou JP, Laurent G, Levade T, Mercadier JJ. Doxorubicin induces slow ceramide accumulation and late apoptosis in cultured adult rat ventricular myocytes. Cardiovascular Research. 43: 398-407. PMID 10536670 DOI: 10.1016/S0008-6363(99)00142-X |
0.343 |
|
| 1999 |
Mansat-de Mas V, Bezombes C, Quillet-Mary A, Bettaïeb A, D'orgeix AD, Laurent G, Jaffrézou JP. Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin. Molecular Pharmacology. 56: 867-74. PMID 10531389 DOI: 10.1124/Mol.56.5.867 |
0.401 |
|
| 1999 |
Andrieu-Abadie N, Jaffrezou JP, Hatem S, Laurent G, Levade T, Mercadier JJ. L-carnitine prevents doxorubicin-induced apoptosis of cardiac myocytes: role of inhibition of ceramide generation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 13: 1501-10. PMID 10463940 DOI: 10.1096/Fasebj.13.12.1501 |
0.379 |
|
| 1999 |
Levade T, Jaffrézou JP. Signalling sphingomyelinases: which, where, how and why? Biochimica Et Biophysica Acta. 1438: 1-17. PMID 10216276 DOI: 10.1016/S1388-1981(99)00038-4 |
0.357 |
|
| 1999 |
Bettaïeb A, Plo I, Mansat-De Mas V, Quillet-Mary A, Levade T, Laurent G, Jaffrézou JP. Daunorubicin- and mitoxantrone-triggered phosphatidylcholine hydrolysis: implication in drug-induced ceramide generation and apoptosis. Molecular Pharmacology. 55: 118-25. PMID 9882705 |
0.359 |
|
| 1998 |
Bruno AP, Laurent G, Averbeck D, Demur C, Bonnet J, Bettaïeb A, Levade T, Jaffrézou JP. Lack of ceramide generation in TF-1 human myeloid leukemic cells resistant to ionizing radiation. Cell Death and Differentiation. 5: 172-82. PMID 10200462 DOI: 10.1038/Sj.Cdd.4400330 |
0.451 |
|
| 1998 |
Jaffrézou JP, Maestre N, de Mas-Mansat V, Bezombes C, Levade T, Laurent G. Positive feedback control of neutral sphingomyelinase activity by ceramide. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 12: 999-1006. PMID 9707172 DOI: 10.1096/Fasebj.12.11.999 |
0.445 |
|
| 1998 |
Jaffrézou JP, Bettaïeb A, Levade T, Laurent G. Antitumor agent-induced apoptosis in myeloid leukemia cells: a controlled suicide. Leukemia & Lymphoma. 29: 453-63. PMID 9643559 DOI: 10.3109/10428199809050905 |
0.475 |
|
| 1998 |
Augé N, Escargueil-Blanc I, Lajoie-Mazenc I, Suc I, Andrieu-Abadie N, Pieraggi MT, Chatelut M, Thiers JC, Jaffrézou JP, Laurent G, Levade T, Nègre-Salvayre A, Salvayre R. Potential role for ceramide in mitogen-activated protein kinase activation and proliferation of vascular smooth muscle cells induced by oxidized low density lipoprotein. The Journal of Biological Chemistry. 273: 12893-900. PMID 9582320 DOI: 10.1074/Jbc.273.21.12893 |
0.375 |
|
| 1998 |
Bezombes C, Maestre N, Laurent G, Levade T, Bettaïeb A, Jaffrézou JP. Restoration of TNF-alpha-induced ceramide generation and apoptosis in resistant human leukemia KG1a cells by the P-glycoprotein blocker PSC833. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 12: 101-9. PMID 9438415 DOI: 10.1096/Fasebj.12.1.101 |
0.408 |
|
| 1997 |
Mansat V, Laurent G, Levade T, Bettaïeb A, Jaffrézou JP. The protein kinase C activators phorbol esters and phosphatidylserine inhibit neutral sphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin. Cancer Research. 57: 5300-4. PMID 9393753 |
0.322 |
|
| 1997 |
Quillet-Mary A, Jaffrézou JP, Mansat V, Bordier C, Naval J, Laurent G. Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis. The Journal of Biological Chemistry. 272: 21388-95. PMID 9261153 DOI: 10.1074/Jbc.272.34.21388 |
0.351 |
|
| 1997 |
Mansat V, Bettaïeb A, Levade T, Laurent G, Jaffrézou JP. Serine protease inhibitors block neutral sphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 11: 695-702. PMID 9240970 DOI: 10.1096/Fasebj.11.8.9240970 |
0.466 |
|
| 1996 |
Bettaieb A, Record M, Côme MG, Bras AC, Chap H, Laurent G, Jaffrézou JP. Opposite effects of tumor necrosis factor alpha on the sphingomyelin-ceramide pathway in two myeloid leukemia cell lines: role of transverse sphingomyelin distribution in the plasma membrane. Blood. 88: 1465-72. PMID 8695867 DOI: 10.1182/Blood.V88.4.1465.Bloodjournal8841465 |
0.388 |
|
| 1996 |
Jaffrézou JP, Levade T, Bettaïeb A, Andrieu N, Bezombes C, Maestre N, Vermeersch S, Rousse A, Laurent G. Daunorubicin-induced apoptosis: triggering of ceramide generation through sphingomyelin hydrolysis. The Embo Journal. 15: 2417-24. PMID 8665849 |
0.364 |
|
| 1994 |
Laredo J, Huynh A, Muller C, Jaffrézou JP, Bailly JD, Cassar G, Laurent G, Demur C. Effect of the protein kinase C inhibitor staurosporine on chemosensitivity to daunorubicin of normal and leukemic fresh myeloid cells. Blood. 84: 229-37. PMID 7912555 |
0.364 |
|
| 1994 |
Muller C, Bailly JD, Goubin F, Laredo J, Jaffrézou JP, Bordier C, Laurent G. Verapamil decreases P-glycoprotein expression in multidrug-resistant human leukemic cell lines. International Journal of Cancer. Journal International Du Cancer. 56: 749-54. PMID 7906257 DOI: 10.1002/Ijc.2910560523 |
0.417 |
|
| 1994 |
Schlaifer D, Meyer K, Muller C, Attal M, Smith MT, Tamaki S, Weimels J, Pris J, Jaffrézou JP, Laurent G. Antisense inhibition of myeloperoxidase increases the sensitivity of the HL-60 cell line to vincristine. Leukemia. 8: 289-91. PMID 7905941 |
0.356 |
|
| 1994 |
Jaffrézou JP, Sikic BI, Laurent G. Cyclosporin A and cyclosporin SDZ PSC 833 enhance anti-CD5 ricin A-chain immunotoxins in human leukemic T cells. Blood. 83: 482-9. PMID 7506953 |
0.454 |
|
| 1993 |
Jaffrézou JP, Laurent G. The intriguing link between modulation of both multidrug resistance and ligand-toxin conjugate cytotoxicity. Febs Letters. 323: 191-7. PMID 8099019 DOI: 10.1016/0014-5793(93)81337-Y |
0.347 |
|
| 1992 |
Jaffrézou JP, Levade T, Chatelain P, Laurent G. Modulation of subcellular distribution of doxorubicin in multidrug-resistant P388/ADR mouse leukemia cells by the chemosensitizer ((2-isopropyl-1-(4-[3-N-methyl-N-(3,4-dimethoxy-beta- phenethyl)amino]propyloxy)-benzenesulfonyl))indolizine. Cancer Research. 52: 6440-6. PMID 1423291 |
0.347 |
|
| 1991 |
Jaffrézou JP, Herbert JM, Levade T, Gau MN, Chatelain P, Laurent G. Reversal of multidrug resistance by calcium channel blocker SR33557 without photoaffinity labeling of P-glycoprotein. The Journal of Biological Chemistry. 266: 19858-64. PMID 1918089 |
0.302 |
|
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