Ken W. Dower, Ph.D. - Publications

Affiliations: 
Brandeis University, Waltham, MA, United States 
Area:
Molecular Genetics of RNA Processing and Behavior

12/31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Zhang C, Dower K, Zhang B, Martinez RV, Lin LL, Zhao S. Computational identification and validation of alternative splicing in ZSF1 rat RNA-seq data, a preclinical model for type 2 diabetic nephropathy. Scientific Reports. 8: 7624. PMID 29769602 DOI: 10.1038/S41598-018-26035-X  0.398
2015 Filone CM, Dower K, Cowley GS, Hensley LE, Connor JH. Probing the virus host interaction in high containment: an approach using pooled short hairpin RNA. Assay and Drug Development Technologies. 13: 34-43. PMID 25646658 DOI: 10.1089/Adt.2014.613  0.308
2014 Filone CM, Caballero IS, Dower K, Mendillo ML, Cowley GS, Santagata S, Rozelle DK, Yen J, Rubins KH, Hacohen N, Root DE, Hensley LE, Connor J. The master regulator of the cellular stress response (HSF1) is critical for orthopoxvirus infection. Plos Pathogens. 10: e1003904. PMID 24516381 DOI: 10.1371/Journal.Ppat.1003904  0.344
2011 Simpson-Holley M, Kedersha N, Dower K, Rubins KH, Anderson P, Hensley LE, Connor JH. Formation of antiviral cytoplasmic granules during orthopoxvirus infection. Journal of Virology. 85: 1581-93. PMID 21147913 DOI: 10.1128/Jvi.02247-10  0.415
2006 Abruzzi KC, Belostotsky DA, Chekanova JA, Dower K, Rosbash M. 3'-end formation signals modulate the association of genes with the nuclear periphery as well as mRNP dot formation. The Embo Journal. 25: 4253-62. PMID 16946703 DOI: 10.1038/Sj.Emboj.7601305  0.649
2004 Kuperwasser N, Brogna S, Dower K, Rosbash M. Nonsense-mediated decay does not occur within the yeast nucleus. Rna (New York, N.Y.). 10: 1907-15. PMID 15547136 DOI: 10.1261/Rna.7132504  0.641
2004 Dower K, Kuperwasser N, Merrikh H, Rosbash M. A synthetic A tail rescues yeast nuclear accumulation of a ribozyme-terminated transcript. Rna (New York, N.Y.). 10: 1888-99. PMID 15547135 DOI: 10.1261/Rna.7166704  0.639
2003 Jensen TH, Dower K, Libri D, Rosbash M. Early formation of mRNP: license for export or quality control? Molecular Cell. 11: 1129-38. PMID 12769839 DOI: 10.1016/S1097-2765(03)00191-6  0.649
2002 Libri D, Dower K, Boulay J, Thomsen R, Rosbash M, Jensen TH. Interactions between mRNA export commitment, 3'-end quality control, and nuclear degradation. Molecular and Cellular Biology. 22: 8254-66. PMID 12417728 DOI: 10.1128/Mcb.22.23.8254-8266.2002  0.728
2002 Dower K, Rosbash M. T7 RNA polymerase-directed transcripts are processed in yeast and link 3' end formation to mRNA nuclear export. Rna (New York, N.Y.). 8: 686-97. PMID 12022234 DOI: 10.1017/S1355838202024068  0.678
2000 Vainberg IE, Dower K, Rosbash M. Nuclear export of heat shock and non-heat-shock mRNA occurs via similar pathways. Molecular and Cellular Biology. 20: 3996-4005. PMID 10805742 DOI: 10.1128/Mcb.20.11.3996-4005.2000  0.618
1998 Viswanathan M, Dower KW, Lovett ST. Identification of a potent DNase activity associated with RNase T of Escherichia coli. The Journal of Biological Chemistry. 273: 35126-31. PMID 9857048 DOI: 10.1074/Jbc.273.52.35126  0.32
Low-probability matches (unlikely to be authored by this person)
2011 Dower K, Rubins KH, Hensley LE, Connor JH. Development of Vaccinia reporter viruses for rapid, high content analysis of viral function at all stages of gene expression. Antiviral Research. 91: 72-80. PMID 21569797 DOI: 10.1016/J.Antiviral.2011.04.014  0.299
2012 Dower K, Filone CM, Hodges EN, Bjornson ZB, Rubins KH, Brown LE, Schaus S, Hensley LE, Connor JH. Identification of a pyridopyrimidinone inhibitor of orthopoxviruses from a diversity-oriented synthesis library. Journal of Virology. 86: 2632-40. PMID 22205744 DOI: 10.1128/Jvi.05416-11  0.296
2008 Dower K, Ellis DK, Saraf K, Jelinsky SA, Lin LL. Innate immune responses to TREM-1 activation: overlap, divergence, and positive and negative cross-talk with bacterial lipopolysaccharide. Journal of Immunology (Baltimore, Md. : 1950). 180: 3520-34. PMID 18292579 DOI: 10.4049/Jimmunol.180.5.3520  0.282
2014 Rozelle DK, Filone CM, Dower K, Connor JH. Vaccinia reporter viruses for quantifying viral function at all stages of gene expression. Journal of Visualized Experiments : Jove. PMID 24894622 DOI: 10.3791/51522  0.278
2012 Luong M, Zhang Y, Chamberlain T, Zhou T, Wright JF, Dower K, Hall JP. Stimulation of TLR4 by recombinant HSP70 requires structural integrity of the HSP70 protein itself. Journal of Inflammation (London, England). 9: 11. PMID 22448747 DOI: 10.1186/1476-9255-9-11  0.273
2017 Hall J, Brault A, Vincent F, Weng S, Wang H, Dumlao D, Aulabaugh A, Aivazian D, Castro D, Chen M, Culp J, Dower K, Gardner J, Hawrylik S, Golenbock D, et al. Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay. Plos One. 12: e0184843. PMID 28934246 DOI: 10.1371/Journal.Pone.0184843  0.259
2013 Chan WM, Bartee EC, Moreb JS, Dower K, Connor JH, McFadden G. Myxoma and vaccinia viruses bind differentially to human leukocytes. Journal of Virology. 87: 4445-60. PMID 23388707 DOI: 10.1128/Jvi.03488-12  0.258
2023 Mukherjee PK, Nguyen QT, Li J, Zhao S, Christensen SM, West GA, Chandra J, Gordon IO, Lin S, Wang J, Mao R, Czarnecki D, Rayan C, Goren I, Banerjee S, ... ... Dower K, et al. Stricturing Crohn's disease single-cell RNA sequencing reveals fibroblast heterogeneity and intercellular interactions. Gastroenterology. PMID 37507073 DOI: 10.1053/j.gastro.2023.07.014  0.241
2023 Mukherjee PK, Nguyen QT, Li J, Zhao S, Christensen SM, West GA, Chandra J, Gordon IO, Lin S, Wang J, Mao R, Czarnecki D, Rayan C, Kotak P, Plesec T, ... ... Dower K, et al. Stricturing Crohn's disease single-cell RNA sequencing reveals fibroblast heterogeneity and intercellular interactions. Biorxiv : the Preprint Server For Biology. PMID 37066202 DOI: 10.1101/2023.04.03.534781  0.241
2014 Cushing L, Stochaj W, Siegel M, Czerwinski R, Dower K, Wright Q, Hirschfield M, Casanova JL, Picard C, Puel A, Lin LL, Rao VR. Interleukin 1/Toll-like receptor-induced autophosphorylation activates interleukin 1 receptor-associated kinase 4 and controls cytokine induction in a cell type-specific manner. The Journal of Biological Chemistry. 289: 10865-75. PMID 24567333 DOI: 10.1074/Jbc.M113.544809  0.237
2016 Primiano MJ, Lefker BA, Bowman MR, Bree AG, Hubeau C, Bonin PD, Mangan M, Dower K, Monks BG, Cushing L, Wang S, Guzova J, Jiao A, Lin LL, Latz E, et al. Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation. Journal of Immunology (Baltimore, Md. : 1950). PMID 27521339 DOI: 10.4049/Jimmunol.1600035  0.223
2017 Dower K, Zhao S, Schlerman FJ, Savary L, Campanholle G, Johnson BG, Xi L, Nguyen V, Zhan Y, Lech MP, Wang J, Nie Q, Karsdal MA, Genovese F, Boucher G, et al. High resolution molecular and histological analysis of renal disease progression in ZSF1 fa/faCP rats, a model of type 2 diabetic nephropathy. Plos One. 12: e0181861. PMID 28746409 DOI: 10.1371/Journal.Pone.0181861  0.222
2018 Homer BL, Dower K. 41-Week Study of Progressive Diabetic Nephropathy in the ZSF1 fa/faCP Rat Model: Toxicologic Pathology. 46: 976-977. PMID 30278832 DOI: 10.1177/0192623318803278  0.222
2017 Lee KL, Ambler CM, Anderson DR, Boscoe BP, Bree AG, Brodfuehrer JI, Chang JS, Choi C, Chung SW, Curran KJ, Day JE, Dehnhardt CM, Dower K, Drozda SE, Frisbie RK, et al. Discovery of Clinical Candidate 1-{[(2S,3S,4S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fragment-Based Drug Design. Journal of Medicinal Chemistry. PMID 28498658 DOI: 10.1021/Acs.Jmedchem.7B00231  0.216
2009 Kuai J, Gregory B, Hill A, Pittman DD, Feldman JL, Brown T, Carito B, O'Toole M, Ramsey R, Adolfsson O, Shields KM, Dower K, Hall JP, Kurdi Y, Beech JT, et al. TREM-1 expression is increased in the synovium of rheumatoid arthritis patients and induces the expression of pro-inflammatory cytokines. Rheumatology (Oxford, England). 48: 1352-8. PMID 19713442 DOI: 10.1093/Rheumatology/Kep235  0.212
2001 Li D, Dower K, Ma Y, Tian Y, Benjamin TL. A tumor host range selection procedure identifies p150(sal2) as a target of polyoma virus large T antigen. Proceedings of the National Academy of Sciences of the United States of America. 98: 14619-24. PMID 11734654 DOI: 10.1073/Pnas.251447198  0.156
2023 Fabre T, Barron AMS, Christensen SM, Asano S, Bound K, Lech MP, Wadsworth MH, Chen X, Wang C, Wang J, McMahon J, Schlerman F, White A, Kravarik KM, Fisher AJ, ... ... Dower K, et al. Identification of a broadly fibrogenic macrophage subset induced by type 3 inflammation. Science Immunology. 8: eadd8945. PMID 37027478 DOI: 10.1126/sciimmunol.add8945  0.098
2023 Wang J, Casimiro-Garcia A, Johnson BG, Duffen J, Cain M, Savary L, Wang S, Nambiar P, Lech M, Zhao S, Xi L, Zhan Y, Olson J, Stejskal JA, Lin H, ... ... Dower K, et al. A protein kinase C α and β inhibitor blunts hyperphagia to halt renal function decline and reduces adiposity in a rat model of obesity-driven type 2 diabetes. Scientific Reports. 13: 16919. PMID 37805649 DOI: 10.1038/s41598-023-43759-7  0.062
2021 Winkler A, Sun W, De S, Jiao A, Nusrat Sharif M, Symanowicz PT, Athale S, Shin JH, Wang J, Jacobson BA, Ramsey SJ, Dower K, Andreyeva T, Liu H, Hegen M, et al. The IRAK4 kinase inhibitor PF-06650833 blocks inflammation in preclinical models of rheumatologic disease and in humans enrolled in a randomized clinical trial. Arthritis & Rheumatology (Hoboken, N.J.). PMID 34423919 DOI: 10.1002/art.41953  0.058
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