Nien-Pei Tsai, Ph.D. - Publications

Pharmacology University of Minnesota, Twin Cities, Minneapolis, MN 

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Eagleman DE, Zhu J, Liu DC, Seimetz J, Kalsotra A, Tsai NP. Unbiased Proteomic Screening Identifies a Novel Role for the E3 Ubiquitin Ligase Nedd4-2 in Translational Suppression During ER Stress. Journal of Neurochemistry. PMID 33064840 DOI: 10.1111/jnc.15219  0.44
2020 Liu DC, Soriano S, Yook Y, Lizarazo S, Eagleman DE, Tsai NP. Chronic activation of Gp1 mGluRs leads to distinct refinement of neural network activity through non-canonical p53 and Akt signaling. Eneuro. PMID 32161037 DOI: 10.1523/ENEURO.0438-19.2020  0.44
2020 Zhu J, Tsai NP. Ubiquitination and E3 Ubiquitin Ligases in Rare Neurological Diseases with Comorbid Epilepsy. Neuroscience. PMID 31931110 DOI: 10.1016/j.neuroscience.2019.12.030  0.4
2019 Liu DC, Eagleman DE, Tsai NP. Novel roles of ER stress in repressing neural activity and seizures through Mdm2- and p53-dependent protein translation. Plos Genetics. 15: e1008364. PMID 31557161 DOI: 10.1371/journal.pgen.1008364  0.44
2019 Zhu J, Lee KY, Jong TT, Tsai NP. C2-lacking isoform of Nedd4-2 regulates excitatory synaptic strength through GluA1 ubiquitination-independent mechanisms. Journal of Neurochemistry. PMID 31357244 DOI: 10.1111/Jnc.14840  0.44
2018 Kim EC, Zhang J, Pang W, Wang S, Lee KY, Cavaretta JP, Walters J, Procko E, Tsai NP, Chung HJ. Reduced axonal surface expression and phosphoinositide sensitivity in K7 channels disrupts their function to inhibit neuronal excitability in Kcnq2 epileptic encephalopathy. Neurobiology of Disease. 118: 76-93. PMID 30008368 DOI: 10.1016/J.Nbd.2018.07.004  0.44
2018 Jewett KA, Lee KY, Eagleman DE, Soriano S, Tsai NP. Dysregulation and restoration of homeostatic network plasticity in fragile X syndrome mice. Neuropharmacology. PMID 29890190 DOI: 10.1016/J.Neuropharm.2018.06.011  0.44
2018 Lee KY, Jewett KA, Chung HJ, Tsai NP. Loss of Fragile X Protein FMRP Impairs Homeostatic Synaptic Downscaling through Tumor Suppressor p53 and Ubiquitin E3 Ligase Nedd4-2. Human Molecular Genetics. PMID 29771335 DOI: 10.1093/Hmg/Ddy189  0.44
2017 Liu DC, Seimetz J, Lee KY, Kalsotra A, Chung HJ, Lu H, Tsai NP. Mdm2 mediates FMRP- and Gp1 mGluR-dependent protein translation and neural network activity. Human Molecular Genetics. 26: 3895-3908. PMID 29016848 DOI: 10.1093/Hmg/Ddx276  0.44
2017 Baculis BC, Weiss AC, Pang W, Jeong HG, Lee JH, Liu DC, Tsai NP, Chung HJ. Prolonged seizure activity causes caspase dependent cleavage and dysfunction of G-protein activated inwardly rectifying potassium channels. Scientific Reports. 7: 12313. PMID 28951616 DOI: 10.1038/S41598-017-12508-Y  0.36
2017 Zhu J, Lee KY, Jewett KA, Man HY, Chung HJ, Tsai NP. Epilepsy-associated gene Nedd4-2 mediates neuronal activity and seizure susceptibility through AMPA receptors. Plos Genetics. 13: e1006634. PMID 28212375 DOI: 10.1371/Journal.Pgen.1006634  0.44
2016 Jewett KA, Christian CA, Bacos JT, Lee KY, Zhu J, Tsai NP. Feedback modulation of neural network synchrony and seizure susceptibility by Mdm2-p53-Nedd4-2 signaling. Molecular Brain. 9: 32. PMID 27000207 DOI: 10.1186/S13041-016-0214-6  0.84
2016 Lin YL, Chen CH, Wu HY, Tsai NM, Jian TY, Chang YC, Lin CH, Wu CH, Hsu FT, Leung TK, Liao KW. Inhibition of breast cancer with transdermal tamoxifen-encapsulated lipoplex. Journal of Nanobiotechnology. 14: 11. PMID 26892504 DOI: 10.1186/s12951-016-0163-3  0.36
2015 Lin YL, Chang KF, Huang XF, Hung CL, Chen SC, Chao WR, Liao KW, Tsai NM. Liposomal n-butylidenephthalide protects the drug from oxidation and enhances its antitumor effects in glioblastoma multiforme. International Journal of Nanomedicine. 10: 6009-20. PMID 26451107 DOI: 10.2147/IJN.S85790  0.36
2015 Jewett KA, Zhu J, Tsai NP. The tumor suppressor p53 guides GluA1 homeostasis through Nedd4-2 during chronic elevation of neuronal activity. Journal of Neurochemistry. 135: 226-33. PMID 26250624 DOI: 10.1111/Jnc.13271  0.84
2014 Tsai NP. Ubiquitin proteasome system-mediated degradation of synaptic proteins: An update from the postsynaptic side. Biochimica Et Biophysica Acta. 1843: 2838-2842. PMID 25135362 DOI: 10.1016/J.Bbamcr.2014.08.006  0.84
2014 Wilkerson JR, Tsai NP, Maksimova MA, Wu H, Cabalo NP, Loerwald KW, Dictenberg JB, Gibson JR, Huber KM. A role for dendritic mGluR5-mediated local translation of Arc/Arg3.1 in MEF2-dependent synapse elimination. Cell Reports. 7: 1589-600. PMID 24857654 DOI: 10.1016/j.celrep.2014.04.035  0.84
2013 Jakkamsetti V, Tsai NP, Gross C, Molinaro G, Collins KA, Nicoletti F, Wang KH, Osten P, Bassell GJ, Gibson JR, Huber KM. Experience-induced Arc/Arg3.1 primes CA1 pyramidal neurons for metabotropic glutamate receptor-dependent long-term synaptic depression. Neuron. 80: 72-9. PMID 24094104 DOI: 10.1016/J.Neuron.2013.07.020  0.84
2013 Pan CQ, Hu KQ, Tsai N. Long-term therapy with nucleoside/nucleotide analogues for chronic hepatitis B in Asian patients Antiviral Therapy. 18: 841-852. PMID 23178555 DOI: 10.3851/IMP2481  0.01
2013 Lin YL, Lai WL, Harn HJ, Hung PH, Hsieh MC, Chang KF, Huang XF, Liao KW, Lee MS, Tsai NM. The methanol extract of angelica sinensis induces cell apoptosis and suppresses tumor growth in human malignant brain tumors Evidence-Based Complementary and Alternative Medicine. 2013. DOI: 10.1155/2013/394636  0.36
2012 Tsai NP, Wilkerson JR, Guo W, Maksimova MA, DeMartino GN, Cowan CW, Huber KM. Multiple autism-linked genes mediate synapse elimination via proteasomal degradation of a synaptic scaffold PSD-95. Cell. 151: 1581-94. PMID 23260144 DOI: 10.1016/J.Cell.2012.11.040  0.84
2012 Ronesi JA, Collins KA, Hays SA, Tsai NP, Guo W, Birnbaum SG, Hu JH, Worley PF, Gibson JR, Huber KM. Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome. Nature Neuroscience. 15: 431-40, S1. PMID 22267161 DOI: 10.1038/nn.3033  0.84
2010 Tsai NP, Lin YL, Tsui YC, Wei LN. Dual action of epidermal growth factor: extracellular signal-stimulated nuclear-cytoplasmic export and coordinated translation of selected messenger RNA. The Journal of Cell Biology. 188: 325-33. PMID 20142421 DOI: 10.1083/Jcb.200910083  0.84
2010 Tsai NP, Tsui YC, Pintar JE, Loh HH, Wei LN. Kappa opioid receptor contributes to EGF-stimulated neurite extension in development. Proceedings of the National Academy of Sciences of the United States of America. 107: 3216-21. PMID 20133770 DOI: 10.1073/pnas.0912367107  0.84
2010 Tsai NP, Wei LN. RhoA/ROCK1 signaling regulates stress granule formation and apoptosis. Cellular Signalling. 22: 668-75. PMID 20004716 DOI: 10.1016/j.cellsig.2009.12.001  0.84
2009 Tsai NP, Huq M, Gupta P, Yamamoto K, Kagechika H, Wei LN. Activation of testicular orphan receptor 4 by fatty acids. Biochimica Et Biophysica Acta. 1789: 734-40. PMID 19800043 DOI: 10.1016/j.bbagrm.2009.09.010  0.84
2009 Tsai NP, Lin YL, Wei LN. MicroRNA mir-346 targets the 5'-untranslated region of receptor-interacting protein 140 (RIP140) mRNA and up-regulates its protein expression. The Biochemical Journal. 424: 411-8. PMID 19780716 DOI: 10.1042/BJ20090915  0.84
2009 Tsai NP, Tsui YC, Wei LN. Dynein motor contributes to stress granule dynamics in primary neurons. Neuroscience. 159: 647-56. PMID 19171178 DOI: 10.1016/J.Neuroscience.2008.12.053  0.84
2008 Gupta P, Ho PC, Huq MM, Ha SG, Park SW, Khan AA, Tsai NP, Wei LN. Retinoic acid-stimulated sequential phosphorylation, PML recruitment, and SUMOylation of nuclear receptor TR2 to suppress Oct4 expression. Proceedings of the National Academy of Sciences of the United States of America. 105: 11424-9. PMID 18682553 DOI: 10.1073/Pnas.0710561105  0.84
2008 Gupta P, Ho PC, Huq MD, Khan AA, Tsai NP, Wei LN. PKCepsilon stimulated arginine methylation of RIP140 for its nuclear-cytoplasmic export in adipocyte differentiation. Plos One. 3: e2658. PMID 18628823 DOI: 10.1371/journal.pone.0002658  0.84
2008 Tsai NP, Ho PC, Wei LN. Regulation of stress granule dynamics by Grb7 and FAK signalling pathway. The Embo Journal. 27: 715-26. PMID 18273060 DOI: 10.1038/emboj.2008.19  0.84
2007 Bi J, Tsai NP, Lu HY, Loh HH, Wei LN. Copb1-facilitated axonal transport and translation of kappa opioid-receptor mRNA. Proceedings of the National Academy of Sciences of the United States of America. 104: 13810-5. PMID 17698811 DOI: 10.1073/Pnas.0703805104  0.84
2007 Tsai NP, Bi J, Wei LN. The adaptor Grb7 links netrin-1 signaling to regulation of mRNA translation. The Embo Journal. 26: 1522-31. PMID 17318180 DOI: 10.1038/Sj.Emboj.7601598  0.84
2007 Huq MD, Tsai NP, Lin YP, Higgins L, Wei LN. Vitamin B6 conjugation to nuclear corepressor RIP140 and its role in gene regulation. Nature Chemical Biology. 3: 161-5. PMID 17277785 DOI: 10.1038/Nchembio861  0.84
2007 Huq MD, Tsai NP, Khan SA, Wei LN. Lysine trimethylation of retinoic acid receptor-alpha: a novel means to regulate receptor function. Molecular & Cellular Proteomics : McP. 6: 677-88. PMID 17205979 DOI: 10.1074/mcp.M600223-MCP200  0.84
2006 Bi J, Tsai NP, Lin YP, Loh HH, Wei LN. Axonal mRNA transport and localized translational regulation of kappa-opioid receptor in primary neurons of dorsal root ganglia. Proceedings of the National Academy of Sciences of the United States of America. 103: 19919-24. PMID 17167054 DOI: 10.1073/Pnas.0607394104  0.84
2006 Mostaqul Huq MD, Gupta P, Tsai NP, White R, Parker MG, Wei LN. Suppression of receptor interacting protein 140 repressive activity by protein arginine methylation. The Embo Journal. 25: 5094-104. PMID 17053781 DOI: 10.1038/sj.emboj.7601389  0.84
2006 Tsai NP, Bi J, Loh HH, Wei LN. Netrin-1 signaling regulates de novo protein synthesis of kappa opioid receptor by facilitating polysomal partition of its mRNA. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9743-9. PMID 16988045 DOI: 10.1523/Jneurosci.3014-06.2006  0.84
2006 Huq MD, Gupta P, Tsai NP, Wei LN. Modulation of testicular receptor 4 activity by mitogen-activated protein kinase-mediated phosphorylation. Molecular & Cellular Proteomics : McP. 5: 2072-82. PMID 16887930 DOI: 10.1074/mcp.M600180-MCP200  0.84
2006 Huq MD, Tsai NP, Gupta P, Wei LN. Regulation of retinal dehydrogenases and retinoic acid synthesis by cholesterol metabolites. The Embo Journal. 25: 3203-13. PMID 16763553 DOI: 10.1038/sj.emboj.7601181  0.84
2006 Tsai NP, Wu YC, Chen JW, Wu CF, Tzeng CM, Syu WJ. Multiple functions of l0036 in the regulation of the pathogenicity island of enterohaemorrhagic Escherichia coli O157:H7. The Biochemical Journal. 393: 591-9. PMID 16248852 DOI: 10.1042/BJ20051201  0.84
2005 Gupta P, Huq MD, Khan SA, Tsai NP, Wei LN. Regulation of co-repressive activity of and HDAC recruitment to RIP140 by site-specific phosphorylation. Molecular & Cellular Proteomics : McP. 4: 1776-84. PMID 16093479 DOI: 10.1074/Mcp.M500236-Mcp200  0.84
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