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Natalie A. Hawryluk, Ph.D. - Publications

Affiliations: 
2001 Brandeis University, Waltham, MA, United States 
Area:
synthetic organic chemistry
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6/22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 Snider BB, Hawryluk NA. ChemInform Abstract: Synthesis of (-)-Dysiherbaine. Cheminform. 31: no-no. DOI: 10.1002/CHIN.200025248  0.533
2004 Lou Y, Horikawa M, Kloster RA, Hawryluk NA, Corey EJ. A new chiral Rh(II) catalyst for enantioselective [2 + 1]-cycloaddition. mechanistic implications and applications. Journal of the American Chemical Society. 126: 8916-8. PMID 15264821 DOI: 10.1021/Ja047064K  0.385
2003 Shi B, Hawryluk NA, Snider BB. Formal synthesis of (+/-)-guanacastepene A. The Journal of Organic Chemistry. 68: 1030-42. PMID 12558432 DOI: 10.1021/Jo026702J  0.553
2001 Snider BB, Hawryluk NA. Synthesis of the hydroazulene ring system of guanacastepene. Organic Letters. 3: 569-72. PMID 11178827 DOI: 10.1021/Ol0069756  0.567
2000 Hawryluk NA, Snider BB. Alcohol inversion using cesium carboxylates and DMAP in toluene. The Journal of Organic Chemistry. 65: 8379-80. PMID 11101401 DOI: 10.1021/Jo0007783  0.453
2000 Snider BB, Hawryluk NA. Synthesis of (-)-dysiherbaine. Organic Letters. 2: 635-8. PMID 10814397 DOI: 10.1021/Ol991393D  0.555
Low-probability matches (unlikely to be authored by this person)
2010 Hawryluk NA, Merit JE, Lebsack AD, Branstetter BJ, Hack MD, Swanson N, Ao H, Maher MP, Bhattacharya A, Wang Q, Freedman JM, Scott BP, Wickenden AD, Chaplan SR, Breitenbucher JG. Discovery and synthesis of 6,7,8,9-tetrahydro-5H-pyrimido-[4,5-d]azepines as novel TRPV1 antagonists. Bioorganic & Medicinal Chemistry Letters. 20: 7137-41. PMID 20947352 DOI: 10.1016/j.bmcl.2010.09.023  0.185
2012 Tichenor MS, Keith JM, Jones WM, Pierce JM, Merit J, Hawryluk N, Seierstad M, Palmer JA, Webb M, Karbarz MJ, Wilson SJ, Wennerholm ML, Woestenborghs F, Beerens D, Luo L, et al. Heteroaryl urea inhibitors of fatty acid amide hydrolase: structure-mutagenicity relationships for arylamine metabolites. Bioorganic & Medicinal Chemistry Letters. 22: 7357-62. PMID 23141911 DOI: 10.1016/j.bmcl.2012.10.076  0.166
2014 Keith JM, Hawryluk N, Apodaca RL, Chambers A, Pierce JM, Seierstad M, Palmer JA, Webb M, Karbarz MJ, Scott BP, Wilson SJ, Luo L, Wennerholm ML, Chang L, Rizzolio M, et al. 1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase. Bioorganic & Medicinal Chemistry Letters. 24: 1280-4. PMID 24513048 DOI: 10.1016/j.bmcl.2014.01.064  0.161
2011 McClure KJ, Maher M, Wu N, Chaplan SR, Eckert WA, Lee DH, Wickenden AD, Hermann M, Allison B, Hawryluk N, Breitenbucher JG, Grice CA. Discovery of a novel series of selective HCN1 blockers. Bioorganic & Medicinal Chemistry Letters. 21: 5197-201. PMID 21824780 DOI: 10.1016/j.bmcl.2011.07.051  0.149
2002 Eggler JF, Gabel CA, Zandi K, Weaver JD, McKechney H, Dombroski MA, Peurano H, Hawryluk N. Synthesis of covalent [14C]-labeled diarylsulfonylurea (DASU) inhibitors of the processing and release of IL-1 Journal of Labelled Compounds and Radiopharmaceuticals. 45: 785-794. DOI: 10.1002/jlcr.602  0.136
2013 Letavic MA, Lord B, Bischoff F, Hawryluk NA, Pieters S, Rech JC, Sales Z, Velter AI, Ao H, Bonaventure P, Contreras V, Jiang X, Morton KL, Scott B, Wang Q, et al. Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X7 Antagonists. Acs Medicinal Chemistry Letters. 4: 419-22. PMID 24900687 DOI: 10.1021/ml400040v  0.133
2022 Hawryluk N, Robinson D, Shen Y, Kyne G, Bedore M, Menon S, Canan S, von Geldern T, Townson S, Gokool S, Ehrens A, Koschel M, Lhermitte-Vallarino N, Martin C, Hoerauf A, et al. Discovery of Substituted Di(pyridin-2-yl)-1,2,4-thiadiazol-5-amines as Novel Macrofilaricidal Compounds for the Treatment of Human Filarial Infections. Journal of Medicinal Chemistry. PMID 35972896 DOI: 10.1021/acs.jmedchem.2c00960  0.13
2001 Corbin PS, Zimmerman SC, Thiessen PA, Hawryluk NA, Murray TJ. Complexation-induced unfolding of heterocyclic ureas. Simple foldamers equilibrate with multiply hydrogen-bonded sheetlike structures. Journal of the American Chemical Society. 123: 10475-88. PMID 11673978 DOI: 10.1021/Ja010638Q  0.122
2010 Lebsack AD, Rech JC, Branstetter BJ, Hawryluk NA, Merit JE, Allison B, Rynberg R, Buma J, Rizzolio M, Swanson N, Ao H, Maher MP, Herrmann M, Freedman J, Scott BP, et al. 1,2-diamino-ethane-substituted-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepines as TRPV1 antagonists with improved properties. Bioorganic & Medicinal Chemistry Letters. 20: 7142-6. PMID 20932750 DOI: 10.1016/j.bmcl.2010.09.006  0.061
2018 Tummalapalli SR, Bhat R, Chojnowski A, Prorok M, Kreiss T, Goldberg R, Canan S, Hawryluk N, Mortensen D, Khetani V, Zeldis J, Siekierka JJ, Rotella DP. Discovery of a Stress-Activated Protein Kinase Inhibitor for Lymphatic Filariasis. Acs Medicinal Chemistry Letters. 9: 210-214. PMID 29541362 DOI: 10.1021/Acsmedchemlett.7B00477  0.054
2018 Mundhra S, Bryk R, Hawryluk N, Zhang T, Jiang X, Nathan CF. Evidence for dispensability of protein kinase R in host control of tuberculosis. European Journal of Immunology. PMID 29436711 DOI: 10.1002/Eji.201747180  0.05
2021 Tasneen R, Mortensen DS, Converse PJ, Urbanowski ME, Upton A, Fotouhi N, Nuermberger E, Hawryluk N. Dual mTORC1/mTORC2 inhibition as a Host-Directed Therapeutic Target in Pathologically Distinct Mouse Models of Tuberculosis. Antimicrobial Agents and Chemotherapy. PMID 33903099 DOI: 10.1128/AAC.00253-21  0.048
2020 Bryk R, Mundhra S, Jiang X, Wood M, Pfau D, Weber E, Park S, Zhang L, Wilson C, Van der Westhuyzen R, Street L, Chibale K, Zimmerman M, Dartois V, Pastore N, ... ... Hawryluk N, et al. Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB. Plos Pathogens. 16: e1008567. PMID 32574211 DOI: 10.1371/Journal.Ppat.1008567  0.041
2022 Hawryluk N, Zhiru L, Carlow C, Gokool S, Townson S, Kreiss T, Chojnowski A, Prorok M, Siekierka J, Ehrens A, Koschel M, Lhermitte-Vallarino N, Martin C, Hoerauf A, Hernandez G, et al. Filarial nematode phenotypic screening cascade to identify compounds with anti-parasitic activity for drug discovery optimization. International Journal For Parasitology. Drugs and Drug Resistance. 19: 89-97. PMID 35834918 DOI: 10.1016/j.ijpddr.2022.06.002  0.035
2020 Hawryluk NA. Macrofilaricides: An Unmet Medical Need for Filarial Diseases. Acs Infectious Diseases. PMID 32091199 DOI: 10.1021/acsinfecdis.9b00469  0.035
2010 Hawryluk NA, Carruthers NI. 2-Pyridinylpiperazine Carboxamide Class and Related TRPV1 Antagonists Vanilloid Receptor Trpv1 in Drug Discovery: Targeting Pain and Other Pathological Disorders. 311-324. DOI: 10.1002/9780470588284.ch12  0.028
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