Simmon P. Brooks - Publications

Affiliations: 
2002-2016 School of Biosciences Cardiff University, Cardiff, Wales, United Kingdom 

70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Yhnell E, Dunnett SB, Brooks SP. A Longitudinal Motor Characterisation of the HdhQ111 Mouse Model of Huntington's Disease. Journal of Huntington's Disease. PMID 27258586 DOI: 10.3233/JHD-160191  1
2016 Bayram-Weston Z, Jones L, Dunnett SB, Brooks SP. Comparison of mHTT Antibodies in Huntington's Disease Mouse Models Reveal Specific Binding Profiles and Steady-State Ubiquitin Levels with Disease Development. Plos One. 11: e0155834. PMID 27196694 DOI: 10.1371/journal.pone.0155834  1
2016 Yhnell E, Lelos MJ, Dunnett SB, Brooks SP. Cognitive training modifies disease symptoms in a mouse model of Huntington's disease. Experimental Neurology. PMID 27163546 DOI: 10.1016/j.expneurol.2016.05.008  1
2016 Brooks S. Foreword. Journal of Neuroscience Methods. PMID 26774755 DOI: 10.1016/j.jneumeth.2016.01.011  1
2015 Bayram-Weston Z, Stone TC, Giles P, Elliston L, Janghra N, Higgs GV, Holmans PA, Dunnett SB, Brooks SP, Jones L. Similar striatal gene expression profiles in the striatum of the YAC128 and HdhQ150 mouse models of Huntington's disease are not reflected in mutant Huntingtin inclusion prevalence. Bmc Genomics. 16: 1079. PMID 26691352 DOI: 10.1186/s12864-015-2251-4  1
2015 Bowles KR, Brooks SP, Dunnett SB, Jones L. Huntingtin Subcellular Localisation Is Regulated by Kinase Signalling Activity in the StHdhQ111 Model of HD. Plos One. 10: e0144864. PMID 26660732 DOI: 10.1371/journal.pone.0144864  1
2015 Bayram-Weston Z, Olsen E, Harrison DJ, Dunnett SB, Brooks SP. Optimising Golgi-Cox staining for use with perfusion-fixed brain tissue validated in the zQ175 mouse model of Huntington's disease. Journal of Neuroscience Methods. PMID 26459195 DOI: 10.1016/j.jneumeth.2015.09.033  1
2015 Steventon JJ, Harrison DJ, Trueman RC, Rosser AE, Jones DK, Brooks SP. In Vivo MRI Evidence that Neuropathology is Attenuated by Cognitive Enrichment in the Yac128 Huntington's Disease Mouse Model. Journal of Huntington's Disease. 4: 149-60. PMID 26397896 DOI: 10.3233/JHD-150147  1
2015 Yhnell E, Dunnett SB, Brooks SP. The utilisation of operant delayed matching and non-matching to position for probing cognitive flexibility and working memory in mouse models of Huntington's disease. Journal of Neuroscience Methods. PMID 26321735 DOI: 10.1016/j.jneumeth.2015.08.022  1
2015 Brooks SP, Dunnett SB. Mouse Models of Huntington's Disease. Current Topics in Behavioral Neurosciences. 22: 101-33. PMID 24357436 DOI: 10.1007/7854_2013_256  1
2014 Hughes AC, Mort M, Elliston L, Thomas RM, Brooks SP, Dunnett SB, Jones L. Identification of novel alternative splicing events in the huntingtin gene and assessment of the functional consequences using structural protein homology modelling. Journal of Molecular Biology. 426: 1428-38. PMID 24389360 DOI: 10.1016/j.jmb.2013.12.028  1
2013 Harrison DJ, Busse M, Openshaw R, Rosser AE, Dunnett SB, Brooks SP. Exercise attenuates neuropathology and has greater benefit on cognitive than motor deficits in the R6/1 Huntington's disease mouse model. Experimental Neurology. 248: 457-69. PMID 23911978 DOI: 10.1016/j.expneurol.2013.07.014  1
2013 Peters OM, Shelkovnikova T, Tarasova T, Springe S, Kukharsky MS, Smith GA, Brooks S, Kozin SA, Kotelevtsev Y, Bachurin SO, Ninkina N, Buchman VL. Chronic administration of Dimebon does not ameliorate amyloid-β pathology in 5xFAD transgenic mice. Journal of Alzheimer's Disease : Jad. 36: 589-96. PMID 23645096 DOI: 10.3233/JAD-130071  1
2013 Brooks SP, Dunnett SB. Cognitive deficits in animal models of basal ganglia disorders. Brain Research Bulletin. 92: 29-40. PMID 22588013 DOI: 10.1016/j.brainresbull.2012.04.011  1
2012 Brooks SP, Trueman RC, Dunnett SB. Assessment of Motor Coordination and Balance in Mice Using the Rotarod, Elevated Bridge, and Footprint Tests. Current Protocols in Mouse Biology. 2: 37-53. PMID 26069004 DOI: 10.1002/9780470942390.mo110165  1
2012 Busse M, Khalil H, Brooks S, Quinn L, Rosser A. Practice, progress and future directions for physical therapies in Huntingtons disease. Journal of Huntington's Disease. 1: 175-85. PMID 25063330 DOI: 10.3233/JHD-120025  1
2012 Trueman RC, Dunnett SB, Jones L, Brooks SP. Five choice serial reaction time performance in the HdhQ92 mouse model of Huntington's disease. Brain Research Bulletin. 88: 163-70. PMID 22085744 DOI: 10.1016/j.brainresbull.2011.10.019  1
2012 Brooks SP, Jones L, Dunnett SB. Comparative analysis of pathology and behavioural phenotypes in mouse models of Huntington's disease. Brain Research Bulletin. 88: 81-93. PMID 22004616 DOI: 10.1016/j.brainresbull.2011.10.002  1
2012 Giles P, Elliston L, Higgs GV, Brooks SP, Dunnett SB, Jones L. Longitudinal analysis of gene expression and behaviour in the HdhQ150 mouse model of Huntington's disease. Brain Research Bulletin. 88: 199-209. PMID 22001697 DOI: 10.1016/j.brainresbull.2011.10.001  1
2012 Fielding SA, Brooks SP, Klein A, Bayram-Weston Z, Jones L, Dunnett SB. Profiles of motor and cognitive impairment in the transgenic rat model of Huntington's disease. Brain Research Bulletin. 88: 223-36. PMID 21963415 DOI: 10.1016/j.brainresbull.2011.09.011  1
2012 Bowles KR, Brooks SP, Dunnett SB, Jones L. Gene expression and behaviour in mouse models of HD. Brain Research Bulletin. 88: 276-84. PMID 21854837 DOI: 10.1016/j.brainresbull.2011.07.021  1
2012 Bayram-Weston Z, Jones L, Dunnett SB, Brooks SP. Light and electron microscopic characterization of the evolution of cellular pathology in the R6/1 Huntington's disease transgenic mice. Brain Research Bulletin. 88: 104-12. PMID 21801812 DOI: 10.1016/j.brainresbull.2011.07.009  1
2012 Brooks SP, Jones L, Dunnett SB. Longitudinal analyses of operant performance on the serial implicit learning task (SILT) in the YAC128 Huntington's disease mouse line. Brain Research Bulletin. 88: 130-6. PMID 21763407 DOI: 10.1016/j.brainresbull.2011.06.008  1
2012 Brooks SP, Janghra N, Higgs GV, Bayram-Weston Z, Heuer A, Jones L, Dunnett SB. Selective cognitive impairment in the YAC128 Huntington's disease mouse. Brain Research Bulletin. 88: 121-9. PMID 21624441 DOI: 10.1016/j.brainresbull.2011.05.010  1
2012 Bayram-Weston Z, Jones L, Dunnett SB, Brooks SP. Light and electron microscopic characterization of the evolution of cellular pathology in YAC128 Huntington's disease transgenic mice. Brain Research Bulletin. 88: 137-47. PMID 21620935 DOI: 10.1016/j.brainresbull.2011.05.005  1
2012 Dunnett SB, Heuer A, Lelos M, Brooks SP, Rosser AE. Bilateral striatal lesions disrupt performance in an operant delayed reinforcement task in rats. Brain Research Bulletin. 88: 251-60. PMID 21515345 DOI: 10.1016/j.brainresbull.2011.04.002  1
2012 Bayram-Weston Z, Jones L, Dunnett SB, Brooks SP. Light and electron microscopic characterization of the evolution of cellular pathology in HdhQ92 Huntington's disease knock-in mice. Brain Research Bulletin. 88: 171-81. PMID 21513775 DOI: 10.1016/j.brainresbull.2011.03.013  1
2012 Bayram-Weston Z, Torres EM, Jones L, Dunnett SB, Brooks SP. Light and electron microscopic characterization of the evolution of cellular pathology in the Hdh(CAG)150 Huntington's disease knock-in mouse. Brain Research Bulletin. 88: 189-98. PMID 21511013 DOI: 10.1016/j.brainresbull.2011.03.014  1
2012 Trueman RC, Dunnett SB, Brooks SP. Operant-based instrumental learning for analysis of genetically modified models of Huntington's disease. Brain Research Bulletin. 88: 261-75. PMID 21440048 DOI: 10.1016/j.brainresbull.2011.03.015  1
2012 Trueman RC, Jones L, Dunnett SB, Brooks SP. Early onset deficits on the delayed alternation task in the Hdh(Q92) knock-in mouse model of Huntington's disease. Brain Research Bulletin. 88: 156-62. PMID 21440047 DOI: 10.1016/j.brainresbull.2011.03.012  1
2012 Deschepper M, Hoogendoorn B, Brooks S, Dunnett SB, Jones L. Proteomic changes in the brains of Huntington's disease mouse models reflect pathology and implicate mitochondrial changes. Brain Research Bulletin. 88: 210-22. PMID 21272615 DOI: 10.1016/j.brainresbull.2011.01.012  1
2012 Brooks SP, Janghra N, Workman VL, Bayram-Weston Z, Jones L, Dunnett SB. Longitudinal analysis of the behavioural phenotype in R6/1 (C57BL/6J) Huntington's disease transgenic mice. Brain Research Bulletin. 88: 94-103. PMID 21272613 DOI: 10.1016/j.brainresbull.2011.01.010  1
2012 Dunnett SB, Fuller A, Rosser AE, Brooks SP. A novel extended sequence learning task (ESLeT) for rodents: validation and the effects of amphetamine, scopolamine and striatal lesions. Brain Research Bulletin. 88: 237-50. PMID 20969933 DOI: 10.1016/j.brainresbull.2010.10.005  1
2012 Brooks S, Higgs G, Janghra N, Jones L, Dunnett SB. Longitudinal analysis of the behavioural phenotype in YAC128 (C57BL/6J) Huntington's disease transgenic mice. Brain Research Bulletin. 88: 113-20. PMID 20460143 DOI: 10.1016/j.brainresbull.2010.05.005  1
2012 Brooks S, Higgs G, Jones L, Dunnett SB. Longitudinal analysis of the behavioural phenotype in Hdh(CAG)150 Huntington's disease knock-in mice. Brain Research Bulletin. 88: 182-8. PMID 20457230 DOI: 10.1016/j.brainresbull.2010.05.004  1
2012 Brooks S, Higgs G, Jones L, Dunnett SB. Longitudinal analysis of the behavioural phenotype in HdhQ92 Huntington's disease knock-in mice. Brain Research Bulletin. 88: 148-55. PMID 20457229 DOI: 10.1016/j.brainresbull.2010.05.003  1
2011 Brooks SP. Neurological evaluation of movement disorders in mice Neuromethods. 61: 65-86. DOI: 10.1007/978-1-61779-298-4_5  1
2010 Brooks SP, Coccia M, Tang HR, Kanuga N, Machesky LM, Bailly M, Cheetham ME, Hardcastle AJ. The Nance-Horan syndrome protein encodes a functional WAVE homology domain (WHD) and is important for co-ordinating actin remodelling and maintaining cell morphology. Human Molecular Genetics. 19: 2421-32. PMID 20332100 DOI: 10.1093/hmg/ddq125  1
2010 Twohig JP, Roberts MI, Gavalda N, Rees-Taylor EL, Giralt A, Adams D, Brooks SP, Bull MJ, Calder CJ, Cuff S, Yong AA, Alberch J, Davies A, Dunnett SB, Tolkovsky AM, et al. Age-dependent maintenance of motor control and corticostriatal innervation by death receptor 3. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3782-92. PMID 20220013 DOI: 10.1523/JNEUROSCI.1928-09.2010  1
2009 Brooks SP, Dunnett SB. Tests to assess motor phenotype in mice: a user's guide. Nature Reviews. Neuroscience. 10: 519-29. PMID 19513088 DOI: 10.1038/nrn2652  1
2009 Brooks SP, Dunnett SB. Lesions of the premotor and supplementary motor areas fail to prevent implicit learning in the operant serial implicit learning task. Brain Research. 1284: 116-24. PMID 19501057 DOI: 10.1016/j.brainres.2009.05.081  1
2009 Brooks S, Fielding S, Döbrössy M, von Hörsten S, Dunnett S. Subtle but progressive cognitive deficits in the female tgHD hemizygote rat as demonstrated by operant SILT performance. Brain Research Bulletin. 79: 310-5. PMID 19480990 DOI: 10.1016/j.brainresbull.2009.03.003  1
2009 Trueman RC, Brooks SP, Jones L, Dunnett SB. Rule learning, visuospatial function and motor performance in the Hdh(Q92) knock-in mouse model of Huntington's disease. Behavioural Brain Research. 203: 215-22. PMID 19445966 DOI: 10.1016/j.bbr.2009.05.006  1
2009 Coccia M, Brooks SP, Webb TR, Christodoulou K, Wozniak IO, Murday V, Balicki M, Yee HA, Wangensteen T, Riise R, Saggar AK, Park SM, Kanuga N, Francis PJ, Maher ER, et al. X-linked cataract and Nance-Horan syndrome are allelic disorders. Human Molecular Genetics. 18: 2643-55. PMID 19414485 DOI: 10.1093/hmg/ddp206  1
2008 Brooks SP, Croft AP, Norman G, Shaw SG, Little HJ. Nimodipine prior to alcohol withdrawal prevents memory deficits during the abstinence phase. Neuroscience. 157: 376-84. PMID 18835336 DOI: 10.1016/j.neuroscience.2008.09.010  1
2008 Little HJ, Croft AP, O'Callaghan MJ, Brooks SP, Wang G, Shaw SG. Selective increases in regional brain glucocorticoid: a novel effect of chronic alcohol. Neuroscience. 156: 1017-27. PMID 18801418 DOI: 10.1016/j.neuroscience.2008.08.029  1
2008 Trueman RC, Brooks SP, Jones L, Dunnett SB. Time course of choice reaction time deficits in the Hdh(Q92) knock-in mouse model of Huntington's disease in the operant serial implicit learning task (SILT). Behavioural Brain Research. 189: 317-24. PMID 18367261 DOI: 10.1016/j.bbr.2008.01.020  1
2008 Hodges A, Hughes G, Brooks S, Elliston L, Holmans P, Dunnett SB, Jones L. Brain gene expression correlates with changes in behavior in the R6/1 mouse model of Huntington's disease. Genes, Brain, and Behavior. 7: 288-99. PMID 17696994 DOI: 10.1111/j.1601-183X.2007.00350.x  1
2007 Brooks SP, Trueman RC, Dunnett SB. Striatal lesions in the mouse disrupt acquisition and retention, but not implicit learning, in the SILT procedural motor learning task. Brain Research. 1185: 179-88. PMID 17964549 DOI: 10.1016/j.brainres.2007.09.017  1
2007 Huang KM, Wu J, Brooks SP, Hardcastle AJ, Lewis RA, Stambolian D. Identification of three novel NHS mutations in families with Nance-Horan syndrome. Molecular Vision. 13: 470-4. PMID 17417607  1
2007 Trueman RC, Brooks SP, Jones L, Dunnett SB. The operant serial implicit learning task reveals early onset motor learning deficits in the Hdh knock-in mouse model of Huntington's disease. The European Journal of Neuroscience. 25: 551-8. PMID 17284197 DOI: 10.1111/j.1460-9568.2007.05307.x  1
2006 Florijn RJ, Loves W, Maillette de Buy Wenniger-Prick LJ, Mannens MM, Tijmes N, Brooks SP, Hardcastle AJ, Bergen AA. New mutations in the NHS gene in Nance-Horan Syndrome families from the Netherlands. European Journal of Human Genetics : Ejhg. 14: 986-90. PMID 16736028 DOI: 10.1038/sj.ejhg.5201671  1
2006 Brooks SP, Betteridge H, Trueman RC, Jones L, Dunnett SB. Selective extra-dimensional set shifting deficit in a knock-in mouse model of Huntington's disease. Brain Research Bulletin. 69: 452-7. PMID 16624677 DOI: 10.1016/j.brainresbull.2006.02.011  1
2005 Croft AP, Brooks SP, Cole J, Little HJ. Social defeat increases alcohol preference of C57BL/10 strain mice; effect prevented by a CCKB antagonist. Psychopharmacology. 183: 163-70. PMID 16205917 DOI: 10.1007/s00213-005-0165-6  1
2005 Brooks SP, Pask T, Jones L, Dunnett SB. Behavioural profiles of inbred mouse strains used as transgenic backgrounds. II: cognitive tests. Genes, Brain, and Behavior. 4: 307-17. PMID 16011577 DOI: 10.1111/j.1601-183X.2004.00109.x  1
2005 Trueman RC, Brooks SP, Dunnett SB. Implicit learning in a serial choice visual discrimination task in the operant 9-hole box by intact and striatal lesioned mice. Behavioural Brain Research. 159: 313-22. PMID 15817194 DOI: 10.1016/j.bbr.2004.11.021  1
2004 Brooks SP, Ebenezer ND, Poopalasundaram S, Lehmann OJ, Moore AT, Hardcastle AJ. Identification of the gene for Nance-Horan syndrome (NHS). Journal of Medical Genetics. 41: 768-71. PMID 15466011 DOI: 10.1136/jmg.2004.022517  1
2004 Brooks S, Ebenezer N, Poopalasundaram S, Maher E, Francis P, Moore A, Hardcastle A. Refinement of the X-linked cataract locus (CXN) and gene analysis for CXN and Nance-Horan syndrome (NHS). Ophthalmic Genetics. 25: 121-31. PMID 15370543 DOI: 10.1080/13816810490514360  1
2004 Brooks SP, Pask T, Jones L, Dunnett SB. Behavioural profiles of inbred mouse strains used as transgenic backgrounds. I: motor tests. Genes, Brain, and Behavior. 3: 206-15. PMID 15248866 DOI: 10.1111/j.1601-183X.2004.00072.x  1
2004 Bensadoun JC, Brooks SP, Dunnett SB. Free operant and discrete trial performance of mice in the nine-hole box apparatus: validation using amphetamine and scopolamine. Psychopharmacology. 174: 396-405. PMID 14985934 DOI: 10.1007/s00213-003-1751-0  1
2004 Brooks SP, Hennebry G, Croft AP, Thomas A, Little HJ. Effects of corticosterone on place conditioning to ethanol. Psychopharmacology. 174: 291-9. PMID 14767631 DOI: 10.1007/s00213-003-1745-y  1
2002 Norman G, Brooks SP, Hennebry GM, Eacott MJ, Little HJ. Nimodipine prevents scopolamine-induced impairments in object recognition. Journal of Psychopharmacology (Oxford, England). 16: 153-61. PMID 12095074  1
2002 Thiselton DL, Alexander C, Taanman JW, Brooks S, Rosenberg T, Eiberg H, Andreasson S, Van Regemorter N, Munier FL, Moore AT, Bhattacharya SS, Votruba M. A comprehensive survey of mutations in the OPA1 gene in patients with autosomal dominant optic atrophy. Investigative Ophthalmology & Visual Science. 43: 1715-24. PMID 12036970  1
2002 Brooks SP, Hennebry G, McAlpin GP, Norman G, Little HJ. Nimodipine prevents the effects of ethanol in tests of memory. Neuropharmacology. 42: 577-85. PMID 11955528 DOI: 10.1016/S0028-3908(02)00006-0  1
2002 O'Callaghan MJ, Croft AP, Watson WP, Brooks SP, Little HJ. Low alcohol preference among the "high alcohol preference" C57/BL10 mice; factors affecting such preference. Pharmacology, Biochemistry, and Behavior. 72: 475-81. PMID 11900822 DOI: 10.1016/S0091-3057(02)00717-7  1
2001 Thiselton DL, Alexander C, Morris A, Brooks S, Rosenberg T, Eiberg H, Kjer B, Kjer P, Bhattacharya SS, Votruba M. A frameshift mutation in exon 28 of the OPA1 gene explains the high prevalence of dominant optic atrophy in the Danish population: Evidence for a founder effect Human Genetics. 109: 498-502. PMID 11735024 DOI: 10.1007/s004390100600  1
2001 Clark A, Lindgren S, Brooks SP, Watson WP, Little HJ. Chronic infusion of nicotine can increase operant self-administration of alcohol. Neuropharmacology. 41: 108-17. PMID 11445191 DOI: 10.1016/S0028-3908(01)00037-5  1
1996 Brooks S, Kaur S, Starr BS, Starr MS. Motor actions of eliprodil in the normal and monoamine-depleted mouse: a role in the treatment of Parkinson's disease? Journal of Neural Transmission (Vienna, Austria : 1996). 103: 737-48. PMID 8836935 DOI: 10.1007/BF01271233  1
1996 Brooks S, Kaur S, Starr B, Starr M. Myorelaxation with glutamate antagonists in mice correlates with inhibition of rearing and grooming Pharmacology Communications. 7: 357-365.  1
1995 Cheeta S, Brooks S, Willner P. Effects of reinforcer sweetness and the D2/D3 antagonist raclopride on progressive ratio operant performance Behavioural Pharmacology. 6: 127-132.  1
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