Paul L. Chazot - Publications

Affiliations: 
Durham University, Durham, England, United Kingdom 
Area:
NMDA, histamine, dopamine, GABA

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Obara I, Telezhkin V, Alrashdi I, Chazot PL. Histamine, histamine receptors, and neuropathic pain relief. British Journal of Pharmacology. 177: 580-599. PMID 31046146 DOI: 10.1111/Bph.14696  0.366
2019 Chazot PL, Johnston L, Mcauley E, Bonner S. Histamine and Delirium: Current Opinion. Frontiers in Pharmacology. 10: 299. PMID 31024298 DOI: 10.3389/Fphar.2019.00299  0.386
2018 Kennedy D, Okello E, Chazot P, Howes MJ, Ohiomokhare S, Jackson P, Haskell-Ramsay C, Khan J, Forster J, Wightman E. Volatile Terpenes and Brain Function: Investigation of the Cognitive and Mood Effects of Mentha × Piperita L. Essential Oil with In Vitro Properties Relevant to Central Nervous System Function. Nutrients. 10. PMID 30087294 DOI: 10.3390/Nu10081029  0.307
2018 Allen SJ, Dixon CJ, Chazot PL. Can H -receptor upregulation and raised histamine explain an anaphylactoid reaction on cessation of ranitidine in a 19-year-old female? A case report. British Journal of Clinical Pharmacology. PMID 29667234 DOI: 10.1111/Bcp.13578  0.343
2016 Veglia E, Pini A, Moggio A, Grange C, Premoselli F, Miglio G, Tiligada K, Fantozzi R, Chazot PL, Rosa AC. Histamine type 1-receptor activation by low dose of histamine undermines human glomerular slit diaphragm integrity. Pharmacological Research. 114: 27-38. PMID 27751877 DOI: 10.1016/J.Phrs.2016.10.011  0.362
2016 Lethbridge NL, Chazot PL. Ligand autoradiographical quantification of histamine H3 receptor in human dementia with Lewy bodies Pharmacological Research. 113: 245-256. PMID 27592250 DOI: 10.1016/J.Phrs.2016.08.034  0.364
2016 Wang JG, Wang YL, Xu F, Zhao JX, Zhou SY, Yu Y, Chazot PL, Wang XF, Lu CB. Activity- and development-dependent down-regulation of TARPγ8 and GluA1 in cultured rat hippocampal neurons. Acta Pharmacologica Sinica. PMID 26725511 DOI: 10.1038/Aps.2015.112  0.308
2015 Panula P, Chazot PL, Cowart M, Gutzmer R, Leurs R, Liu WL, Stark H, Thurmond RL, Haas HL. International Union of Basic and Clinical Pharmacology. XCVIII. Histamine Receptors. Pharmacological Reviews. 67: 601-55. PMID 26084539 DOI: 10.1124/Pr.114.010249  0.351
2015 Abuhamdah S, Abuhamdah R, Howes MJ, Al-Olimat S, Ennaceur A, Chazot PL. Pharmacological and neuroprotective profile of an essential oil derived from leaves of Aloysia citrodora Palau. The Journal of Pharmacy and Pharmacology. PMID 25877296 DOI: 10.1111/Jphp.12424  0.308
2015 Chen Y, Paavola J, Stegajev V, Stark H, Chazot PL, Wen JG, Konttinen YT. Activation of histamine H3 receptor decreased cytoplasmic Ca(2+) imaging during electrical stimulation in the skeletal myotubes. European Journal of Pharmacology. 754: 173-8. PMID 25746421 DOI: 10.1016/J.Ejphar.2015.02.035  0.357
2015 Veglia E, Grange C, Pini A, Moggio A, Lanzi C, Camussi G, Chazot PL, Rosa AC. Histamine receptor expression in human renal tubules: a comparative pharmacological evaluation. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 64: 261-70. PMID 25725698 DOI: 10.1007/S00011-015-0807-Z  0.303
2015 Chen Y, Stegaev V, Kouri VP, Sillat T, Chazot PL, Stark H, Wen JG, Konttinen YT. Identification of histamine receptor subtypes in skeletal myogenesis. Molecular Medicine Reports. 11: 2624-30. PMID 25500891 DOI: 10.3892/Mmr.2014.3073  0.307
2014 Dib K, Perecko T, Jenei V, McFarlane C, Comer D, Brown V, Katebe M, Scheithauer T, Thurmond RL, Chazot PL, Ennis M. The histamine H4 receptor is a potent inhibitor of adhesion-dependent degranulation in human neutrophils. Journal of Leukocyte Biology. 96: 411-8. PMID 24799603 DOI: 10.1189/Jlb.2Ab0813-432Rr  0.409
2013 Ballerini C, Aldinucci A, Luccarini I, Galante A, Manuelli C, Blandina P, Katebe M, Chazot PL, Masini E, Passani MB. Antagonism of histamine H4 receptors exacerbates clinical and pathological signs of experimental autoimmune encephalomyelitis. British Journal of Pharmacology. 170: 67-77. PMID 23735232 DOI: 10.1111/Bph.12263  0.385
2012 Abuhamdah RM, van Rensburg R, Lethbridge NL, Ennaceur A, Chazot PL. Effects of methimepip and JNJ-5207852 in Wistar rats exposed to an open-field with and without object and in Balb/c mice exposed to a radial-arm maze. Frontiers in Systems Neuroscience. 6: 54. PMID 22811660 DOI: 10.3389/Fnsys.2012.00054  0.328
2012 Stegaev V, Sillat T, Porola P, Hänninen A, Falus A, Mieliauskaite D, Buzás E, Rotar Z, Mackiewicz Z, Stark H, Chazot PL, Konttinen YT. Brief report: first identification of Hâ‚„ histamine receptor in healthy salivary glands and in focal sialadenitis in Sjögren's syndrome. Arthritis and Rheumatism. 64: 2663-8. PMID 22488408 DOI: 10.1002/Art.34484  0.387
2012 Gutzmer R, Werfel T, Bäumer W, Kietzmann M, Chazot PL, Leurs R. Well characterized antihistamine 4 receptor antibodies contribute to current knowledge of the expression and biology of the human and murine histamine 4 receptor. Naunyn-Schmiedeberg's Archives of Pharmacology. 385: 853-4; author reply . PMID 22411357 DOI: 10.1007/S00210-012-0744-0  0.346
2012 Wang M, Chazot PL, Ali S, Duckett SF, Obrenovitch TP. Effects of NMDA receptor antagonists with different subtype selectivities on retinal spreading depression. British Journal of Pharmacology. 165: 235-44. PMID 21699507 DOI: 10.1111/J.1476-5381.2011.01553.X  0.378
2011 Tiligada E, Kyriakidis K, Chazot PL, Passani MB. Histamine pharmacology and new CNS drug targets. Cns Neuroscience & Therapeutics. 17: 620-8. PMID 22070192 DOI: 10.1111/J.1755-5949.2010.00212.X  0.37
2010 Chazot PL. Therapeutic potential of histamine H3 receptor antagonists in dementias. Drug News & Perspectives. 23: 99-103. PMID 20369074 DOI: 10.1358/Dnp.2010.23.2.1475899  0.329
2010 Lethbridge NL, Chazot PL. Immunological identification of the mouse H4 histamine receptor on spinal cord motor neurons using a novel anti-mouse H4R antibody. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 59: S197-8. PMID 20020316 DOI: 10.1007/S00011-009-0127-2  0.38
2009 Giannoni P, Passani MB, Nosi D, Chazot PL, Shenton FC, Medhurst AD, Munari L, Blandina P. Heterogeneity of histaminergic neurons in the tuberomammillary nucleus of the rat. The European Journal of Neuroscience. 29: 2363-74. PMID 19490084 DOI: 10.1111/J.1460-9568.2009.06765.X  0.313
2009 Connelly WM, Shenton FC, Lethbridge N, Leurs R, Waldvogel HJ, Faull RL, Lees G, Chazot PL. The histamine H4 receptor is functionally expressed on neurons in the mammalian CNS. British Journal of Pharmacology. 157: 55-63. PMID 19413571 DOI: 10.1111/J.1476-5381.2009.00227.X  0.425
2009 Leurs R, Chazot PL, Shenton FC, Lim HD, de Esch IJ. Molecular and biochemical pharmacology of the histamine H4 receptor. British Journal of Pharmacology. 157: 14-23. PMID 19413568 DOI: 10.1111/J.1476-5381.2009.00250.X  0.394
2009 Chazot PL. Advances in histamine pharmacology reveal new drug targets. British Journal of Pharmacology. 157: 1-3. PMID 19413566 DOI: 10.1111/J.1476-5381.2009.00228.X  0.341
2009 Lethbridge NL, Shenton FC, Chazot PL. Generation and characterisation of the first anti-human H3R445/453 isoform specific antibody probe. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 58: 43-4. PMID 19271149 DOI: 10.1007/S00011-009-2000-8  0.391
2008 Huang L, Abuhamdah S, Howes MJ, Dixon CL, Elliot MS, Ballard C, Holmes C, Burns A, Perry EK, Francis PT, Lees G, Chazot PL. Pharmacological profile of essential oils derived from Lavandula angustifolia and Melissa officinalis with anti-agitation properties: focus on ligand-gated channels. The Journal of Pharmacy and Pharmacology. 60: 1515-22. PMID 18957173 DOI: 10.1211/Jpp/60.11.0013  0.333
2008 Bäumer W, Wendorff S, Gutzmer R, Werfel T, Dijkstra D, Chazot P, Stark H, Kietzmann M. Histamine H4 receptors modulate dendritic cell migration through skin--immunomodulatory role of histamine. Allergy. 63: 1387-1394. PMID 18782117 DOI: 10.1111/J.1398-9995.2008.01720.X  0.335
2008 van Rijn RM, van Marle A, Chazot PL, Langemeijer E, Qin Y, Shenton FC, Lim HD, Zuiderveld OP, Sansuk K, Dy M, Smit MJ, Tensen CP, Bakker RA, Leurs R. Cloning and characterization of dominant negative splice variants of the human histamine H4 receptor. The Biochemical Journal. 414: 121-31. PMID 18452403 DOI: 10.1042/Bj20071583  0.324
2008 Grandi D, Shenton FC, Chazot PL, Morini G. Immunolocalization of histamine H3 receptors on endocrine cells in the rat gastrointestinal tract. Histology and Histopathology. 23: 789-98. PMID 18437677 DOI: 10.14670/Hh-23.789  0.34
2008 Morini G, Becchi G, Shenton FC, Chazot PL, Grandi D. Histamine H3 and H4 receptors are expressed on distinct endocrine cell types in the rat fundic mucosa. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 57: S57-8. PMID 18345490 DOI: 10.1007/S00011-007-0628-9  0.376
2008 Abuhamdah S, Huang L, Elliott MS, Howes MJ, Ballard C, Holmes C, Burns A, Perry EK, Francis PT, Lees G, Chazot PL. Pharmacological profile of an essential oil derived from Melissa officinalis with anti-agitation properties: focus on ligand-gated channels. The Journal of Pharmacy and Pharmacology. 60: 377-84. PMID 18284819 DOI: 10.1211/Jpp.60.3.0014  0.343
2008 Dijkstra D, Stark H, Chazot PL, Shenton FC, Leurs R, Werfel T, Gutzmer R. Human inflammatory dendritic epidermal cells express a functional histamine H4 receptor. The Journal of Investigative Dermatology. 128: 1696-703. PMID 18239617 DOI: 10.1038/Sj.Jid.5701250  0.359
2008 Chaffey H, Chazot PL. NMDA receptor subtypes: Structure, function and therapeutics Current Anaesthesia and Critical Care. 19: 183-201. DOI: 10.1016/J.Cacc.2008.05.004  0.348
2008 van Rensburg R, Chazot PL. Alpha 7 nicotinic acetylcholine receptors: Molecular pharmacology and role in neuroprotection Current Anaesthesia and Critical Care. 19: 202-214. DOI: 10.1016/J.Cacc.2008.05.001  0.319
2007 Chazot P, Shenton F, Schunack W, Grandi D, Morini G. Influence of (R)-alpha-methylhistamine on the histamine H3 receptor in the rat gastrointestinal tract. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 56: S19-20. PMID 17806162 DOI: 10.1007/S00011-006-0509-7  0.334
2007 Dijkstra D, Leurs R, Chazot P, Shenton FC, Stark H, Werfel T, Gutzmer R. Histamine downregulates monocyte CCL2 production through the histamine H4 receptor. The Journal of Allergy and Clinical Immunology. 120: 300-7. PMID 17507084 DOI: 10.1016/J.Jaci.2007.03.024  0.337
2006 van Rijn RM, Chazot PL, Shenton FC, Sansuk K, Bakker RA, Leurs R. Oligomerization of recombinant and endogenously expressed human histamine H(4) receptors. Molecular Pharmacology. 70: 604-15. PMID 16645125 DOI: 10.1124/Mol.105.020818  0.353
2006 Shenton FC, Chazot PL. Probing the importance of N-glycosylation for [(3)H] clobenpropit binding to human H (3) receptors expressed in HEK 293 cells . 3. Molecular and chemical aspects of the histamine receptors. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 55: S40-1. PMID 16547815 DOI: 10.1007/S00011-005-0033-1  0.394
2006 Bakker RA, Lozada AF, van Marle A, Shenton FC, Drutel G, Karlstedt K, Hoffmann M, Lintunen M, Yamamoto Y, van Rijn RM, Chazot PL, Panula P, Leurs R. Discovery of naturally occurring splice variants of the rat histamine H3 receptor that act as dominant-negative isoforms. Molecular Pharmacology. 69: 1194-206. PMID 16415177 DOI: 10.1124/Mol.105.019299  0.362
2005 Shenton FC, Hann V, Chazot PL. Evidence for native and cloned H3 histamine receptor higher oligomers. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 54: S48-9. PMID 15928831 DOI: 10.1007/S00011-004-0422-X  0.395
2005 Chazot PL. Histamine H3 receptors: Potential novel target for analgesia Current Anaesthesia and Critical Care. 16: 94-98. DOI: 10.1016/J.Cacc.2005.03.003  0.388
2004 Hann V, Shenton FC, Chazot PL. GTP-insensitive agonist binding to native and recombinant H(3) receptors. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 53: S67-8. PMID 15054623 DOI: 10.1007/S00011-003-0332-3  0.38
2004 Chazot PL. The NMDA receptor NR2B subunit: a valid therapeutic target for multiple CNS pathologies. Current Medicinal Chemistry. 11: 389-96. PMID 14965239 DOI: 10.2174/0929867043456061  0.35
2004 Chazot PL, Shenton FC. H3 histamine receptors: The gene knockout data so far Current Anaesthesia and Critical Care. 15: 23-28. DOI: 10.1016/J.Cacc.2004.01.006  0.39
2003 Rezai N, Duggan C, Cairns D, Lees G, Chazot PL. Modulation of [3H] TBOB binding to the rodent GABAA receptor by simple disaccharides. Biochemical Pharmacology. 65: 619-23. PMID 12566090 DOI: 10.1016/S0006-2952(02)01611-8  0.381
2002 Chazot PL, Godukhin OV, McDonald A, Obrenovitch TP. Spreading depression-induced preconditioning in the mouse cortex: differential changes in the protein expression of ionotropic nicotinic acetylcholine and glutamate receptors. Journal of Neurochemistry. 83: 1235-8. PMID 12437595 DOI: 10.1046/J.1471-4159.2002.01240.X  0.336
2002 Thompson CL, Drewery DL, Atkins HD, Stephenson FA, Chazot PL. Immunohistochemical localization of N-methyl-D-aspartate receptor subunits in the adult murine hippocampal formation: evidence for a unique role of the NR2D subunit. Brain Research. Molecular Brain Research. 102: 55-61. PMID 12191494 DOI: 10.1016/S0169-328X(02)00183-3  0.306
2002 Chazot PL, Lawrence S, Thompson CL. Studies on the subtype selectivity of CP-101,606: evidence for two classes of NR2B-selective NMDA receptor antagonists. Neuropharmacology. 42: 319-24. PMID 11897110 DOI: 10.1016/S0028-3908(01)00191-5  0.383
2002 Obrenovitch TP, Godukhin OV, Chazot PL. Repetitive spreading depression induces nestin protein expression in the cortex of rats and mice. Is this upregulation initiated by N-methyl-D-aspartate receptors? Neuroscience Letters. 320: 161-3. PMID 11852186 DOI: 10.1016/S0304-3940(02)00046-0  0.318
2001 Chazot PL, Hann V, Wilson C, Lees G, Thompson CL. Immunological identification of the mammalian H3 histamine receptor in the mouse brain. Neuroreport. 12: 259-62. PMID 11209931 DOI: 10.1097/00001756-200102120-00016  0.375
2000 Chopra B, Chazot PL, Stephenson FA. Characterization of the binding of two novel glycine site antagonists to cloned NMDA receptors: evidence for two pharmacological classes of antagonists. British Journal of Pharmacology. 130: 65-72. PMID 10780999 DOI: 10.1038/Sj.Bjp.0703298  0.325
1998 Chazot PL, Reiss C, Chopra B, Stephenson FA. [3H]MDL 105,519 binds with equal high affinity to both assembled and unassembled NR1 subunits of the NMDA receptor. European Journal of Pharmacology. 353: 137-40. PMID 9721050 DOI: 10.1016/S0014-2999(98)00431-2  0.365
1995 Chazot PL, Cik M, Stephenson FA. An investigation into the role of N-glycosylation in the functional expression of a recombinant heteromeric NMDA receptor. Molecular Membrane Biology. 12: 331-7. PMID 8747278 DOI: 10.3109/09687689509072435  0.35
1993 Chazot PL, Fotherby A, Stephenson FA. Evidence for the involvement of a carboxyl group in the vicinity of the MK801 and magnesium ion binding site of the N-methyl-D-aspartate receptor. Biochemical Pharmacology. 45: 605-10. PMID 8442760 DOI: 10.1016/0006-2952(93)90133-H  0.329
1993 Cik M, Chazot PL, Stephenson FA. Optimal expression of cloned NMDAR1/NMDAR2A heteromeric glutamate receptors: a biochemical characterization. The Biochemical Journal. 296: 877-83. PMID 7904155 DOI: 10.1042/Bj2960877  0.385
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