| Year |
Citation |
Score |
| 2021 |
Dolejší E, Chetverikov N, Szánti-Pintér E, Nelic D, Randáková A, Doležal V, El-Fakahany EE, Kudová E, Jakubík J. Neuroactive steroids, WIN-compounds and cholesterol share a common binding site on muscarinic acetylcholine receptors. Biochemical Pharmacology. 192: 114699. PMID 34324870 DOI: 10.1016/j.bcp.2021.114699 |
0.425 |
|
| 2021 |
Jakubík J, El-Fakahany EE. Allosteric Modulation of GPCRs of Class A by Cholesterol. International Journal of Molecular Sciences. 22. PMID 33669406 DOI: 10.3390/ijms22041953 |
0.333 |
|
| 2020 |
Jakubík J, Randáková A, Chetverikov N, El-Fakahany EE, Doležal V. The operational model of allosteric modulation of pharmacological agonism. Scientific Reports. 10: 14421. PMID 32879329 DOI: 10.1038/s41598-020-71228-y |
0.452 |
|
| 2020 |
Randáková A, Nelic D, Doležal V, El-Fakahany EE, Boulos J, Jakubík J. Agonist-Specific Conformations of the M Muscarinic Acetylcholine Receptor Assessed by Molecular Dynamics. Journal of Chemical Information and Modeling. PMID 32130001 DOI: 10.1021/acs.jcim.0c00041 |
0.567 |
|
| 2020 |
Jakubik J, El-Fakahany EE. Current Advances in Allosteric Modulation of Muscarinic Receptors. Biomolecules. 10. PMID 32085536 DOI: 10.3390/biom10020325 |
0.462 |
|
| 2020 |
Randáková A, Nelic D, Ungerová D, Nwokoye P, Su Q, Doležal V, El-Fakahany EE, Boulos J, Jakubík J. Novel M -selective, G -biased agonists of muscarinic acetylcholine receptors. British Journal of Pharmacology. PMID 31910288 DOI: 10.1111/bph.14970 |
0.383 |
|
| 2019 |
Jakubík J, Randáková A, El-Fakahany EE, Doležal V. Analysis of equilibrium binding of an orthosteric tracer and two allosteric modulators. Plos One. 14: e0214255. PMID 30917186 DOI: 10.1371/journal.pone.0214255 |
0.492 |
|
| 2019 |
Jakubík J, Randáková A, Rudajev V, Zimčík P, El-Fakahany EE, Doležal V. Applications and limitations of fitting of the operational model to determine relative efficacies of agonists. Scientific Reports. 9: 4637. PMID 30874590 DOI: 10.1038/s41598-019-40993-w |
0.401 |
|
| 2018 |
Randáková A, Dolejší E, Rudajev V, Zimčík P, Doležal V, El-Fakahany EE, Jakubík J. Role of membrane cholesterol in differential sensitivity of muscarinic receptor subtypes to persistently bound xanomeline. Neuropharmacology. 133: 129-144. PMID 29407765 DOI: 10.1016/j.neuropharm.2018.01.027 |
0.551 |
|
| 2017 |
Jakubík J, Randáková A, Zimčík P, El-Fakahany EE, Doležal V. Binding of N-methylscopolamine to the extracellular domain of muscarinic acetylcholine receptors. Scientific Reports. 7: 40381. PMID 28091608 DOI: 10.1038/srep40381 |
0.542 |
|
| 2016 |
Jakubik J, El-Fakahany EE. Allosteric modulation of muscarinic receptors Neuromethods. 107: 95-130. DOI: 10.1007/978-1-4939-2858-3_6 |
0.431 |
|
| 2016 |
El-Fakahany EE, Jakubik J. Radioligand binding at muscarinic receptors Neuromethods. 107: 37-68. DOI: 10.1007/978-1-4939-2858-3_3 |
0.576 |
|
| 2016 |
Alquicer G, Doležal V, El-Fakahany EE. Utilization of superfused cerebral slices in probing muscarinic receptor autoregulation of acetylcholine release Neuromethods. 107: 221-233. DOI: 10.1007/978-1-4939-2858-3_12 |
0.483 |
|
| 2015 |
Jakubík J, El-Fakahany EE, Doležal V. Towards predictive docking at aminergic G-protein coupled receptors. Journal of Molecular Modeling. 21: 284. PMID 26453085 DOI: 10.1007/s00894-015-2824-9 |
0.332 |
|
| 2015 |
Randáková A, Dolejší E, Rudajev V, Zimčík P, Doležal V, El-Fakahany EE, Jakubík J. Classical and atypical agonists activate M1 muscarinic acetylcholine receptors through common mechanisms. Pharmacological Research. 97: 27-39. PMID 25882246 DOI: 10.1016/j.phrs.2015.04.002 |
0.485 |
|
| 2015 |
Michal P, El-Fakahany EE, Doležal V. Changes in Membrane Cholesterol Differentially Influence Preferential and Non-preferential Signaling of the M1 and M3 Muscarinic Acetylcholine Receptors. Neurochemical Research. 40: 2068-77. PMID 24821386 DOI: 10.1007/s11064-014-1325-z |
0.383 |
|
| 2014 |
Jakubík J, Zimčík P, Randáková A, Fuksová K, El-Fakahany EE, Doležal V. Molecular mechanisms of methoctramine binding and selectivity at muscarinic acetylcholine receptors. Molecular Pharmacology. 86: 180-92. PMID 24870405 DOI: 10.1124/mol.114.093310 |
0.586 |
|
| 2014 |
Jakubík J, Šantrůcková E, Randáková A, Janíčková H, Zimčík P, Rudajev V, Michal P, El-Fakahany EE, Doležal V. Outline of therapeutic interventions with muscarinic receptor-mediated transmission Physiological Research. 63: S177-S189. PMID 24564657 |
0.541 |
|
| 2014 |
Šantrůčková E, Doležal V, El-Fakahany EE, Jakubík J. Long-term activation upon brief exposure to xanomleline is unique to M1 and M4 subtypes of muscarinic acetylcholine receptors. Plos One. 9: e88910. PMID 24558448 DOI: 10.1371/journal.pone.0088910 |
0.59 |
|
| 2013 |
Janíčková H, Rudajev V, Zimčík P, Jakubík J, Tanila H, El-Fakahany EE, Doležal V. Uncoupling of M1 muscarinic receptor/G-protein interaction by amyloid β(1-42). Neuropharmacology. 67: 272-83. PMID 23206502 DOI: 10.1016/j.neuropharm.2012.11.014 |
0.448 |
|
| 2011 |
Jakubík J, Janíčková H, Randáková A, El-Fakahany EE, Doležal V. Subtype differences in pre-coupling of muscarinic acetylcholine receptors. Plos One. 6: e27732. PMID 22110745 DOI: 10.1371/journal.pone.0027732 |
0.417 |
|
| 2011 |
Jakubík J, Janíčková H, El-Fakahany EE, Doležal V. Negative cooperativity in binding of muscarinic receptor agonists and GDP as a measure of agonist efficacy British Journal of Pharmacology. 162: 1029-1044. PMID 20958290 DOI: 10.1111/j.1476-5381.2010.01081.x |
0.498 |
|
| 2010 |
Jakubík J, El-Fakahany EE. Allosteric Modulation of Muscarinic Acetylcholine Receptors. Pharmaceuticals (Basel, Switzerland). 3: 2838-2860. PMID 27713379 DOI: 10.3390/ph3092838 |
0.517 |
|
| 2010 |
Grant MK, Noetzel MJ, De Lorme KC, Jakubík J, Doležal V, El-Fakahany EE. Pharmacological evaluation of the long-term effects of xanomeline on the M(1) muscarinic acetylcholine receptor. Plos One. 5: e15722. PMID 21203415 DOI: 10.1371/journal.pone.0015722 |
0.772 |
|
| 2010 |
Jakubík J, El-Fakahany EE. Allosteric modulation of muscarinic acetylcholine receptors Pharmaceuticals. 3: 2838-2860. DOI: 10.3390/ph3092838 |
0.515 |
|
| 2009 |
Jakubík J, Randáková A, El-Fakahany EE, Dolezal V. Divergence of allosteric effects of rapacuronium on binding and function of muscarinic receptors. Bmc Pharmacology. 9: 15. PMID 20038295 DOI: 10.1186/1471-2210-9-15 |
0.616 |
|
| 2009 |
Cabadak H, Cuadra AE, El-Fakahany EE, Kan B. M2, M3, and M4 muscarinic receptors are expressed in the guinea pig gallbladder. Journal of Receptor and Signal Transduction Research. 29: 63-6. PMID 19519171 DOI: 10.1080/10799890802687416 |
0.401 |
|
| 2009 |
Noetzel MJ, Grant MK, El-Fakahany EE. Mechanisms of M3 muscarinic receptor regulation by wash-resistant xanomeline binding. Pharmacology. 83: 301-17. PMID 19401618 DOI: 10.1159/000214843 |
0.771 |
|
| 2009 |
Michal P, Rudajev V, El-Fakahany EE, Dolezal V. Membrane cholesterol content influences binding properties of muscarinic M2 receptors and differentially impacts activation of second messenger pathways. European Journal of Pharmacology. 606: 50-60. PMID 19374848 DOI: 10.1016/j.ejphar.2009.01.028 |
0.477 |
|
| 2009 |
Noetzel MJ, Grant MK, El-Fakahany EE. Immediate and delayed consequences of xanomeline wash-resistant binding at the M3 muscarinic receptor. Neurochemical Research. 34: 1138-49. PMID 19082883 DOI: 10.1007/s11064-008-9886-3 |
0.753 |
|
| 2008 |
Kane BE, Grant MK, El-Fakahany EE, Ferguson DM. Synthesis and evaluation of xanomeline analogs--probing the wash-resistant phenomenon at the M1 muscarinic acetylcholine receptor. Bioorganic & Medicinal Chemistry. 16: 1376-92. PMID 17977730 DOI: 10.1016/J.Bmc.2007.10.058 |
0.558 |
|
| 2007 |
De Lorme KC, Grant MK, Noetzel MJ, Polson SB, El-Fakahany EE. Long-term changes in the muscarinic M1 receptor induced by instantaneous formation of wash-resistant xanomeline-receptor complex. The Journal of Pharmacology and Experimental Therapeutics. 323: 868-76. PMID 17855477 DOI: 10.1124/jpet.107.129940 |
0.767 |
|
| 2007 |
Machová E, Jakubík J, El-Fakahany EE, Doležal V. Wash-resistantly bound xanomeline inhibits acetylcholine release by persistent activation of presynaptic M2 and M4 muscarinic receptors in rat brain Journal of Pharmacology and Experimental Therapeutics. 322: 316-323. PMID 17446301 DOI: 10.1124/jpet.107.122093 |
0.486 |
|
| 2007 |
Michal P, El-Fakahany EE, Doležal V. Muscarinic M2 receptors directly activate Gq/11 and Gs G-proteins Journal of Pharmacology and Experimental Therapeutics. 320: 607-614. PMID 17065363 DOI: 10.1124/jpet.106.114314 |
0.448 |
|
| 2006 |
De Lorme KC, Sikorski KL, Grant MK, El-Fakahany EE. Long-term wash-resistant effects of brief interaction of xanomeline at the M1 muscarinic receptor. Neuroscience Letters. 410: 11-4. PMID 17052840 DOI: 10.1016/j.neulet.2006.09.062 |
0.58 |
|
| 2006 |
Jakubík J, El-Fakahany EE, Dolezal V. Differences in kinetics of xanomeline binding and selectivity of activation of G proteins at M(1) and M(2) muscarinic acetylcholine receptors. Molecular Pharmacology. 70: 656-66. PMID 16675658 DOI: 10.1124/mol.106.023762 |
0.601 |
|
| 2005 |
Grant MK, El-Fakahany EE. Persistent binding and functional antagonism by xanomeline at the muscarinic M5 receptor. The Journal of Pharmacology and Experimental Therapeutics. 315: 313-9. PMID 16002459 DOI: 10.1124/jpet.105.090134 |
0.624 |
|
| 2005 |
Cuadra AE, El-Fakahany EE. Mechanisms of M(1) muscarinic receptor-mediated up-regulation of neuronal nitric oxide synthase in N1E-115 neuroblastoma cells. Brain Research. Molecular Brain Research. 134: 198-204. PMID 15836917 DOI: 10.1016/j.molbrainres.2004.10.022 |
0.362 |
|
| 2004 |
Jakubík J, Tucek S, El-Fakahany EE. Role of receptor protein and membrane lipids in xanomeline wash-resistant binding to muscarinic M1 receptors. The Journal of Pharmacology and Experimental Therapeutics. 308: 105-10. PMID 14569060 DOI: 10.1124/jpet.103.058594 |
0.551 |
|
| 2002 |
Linden DR, el-Fakahany EE. Arachidonic acid inhibition of muscarinic receptor-mediated nitric oxide production occurs at the level of calcium mobilization in Chinese hamster ovary cells. Neurochemical Research. 27: 441-9. PMID 12199147 DOI: 10.1023/A:1019892700049 |
0.396 |
|
| 2002 |
Jakubík J, Tucek S, El-Fakahany EE. Allosteric modulation by persistent binding of xanomeline of the interaction of competitive ligands with the M1 muscarinic acetylcholine receptor. The Journal of Pharmacology and Experimental Therapeutics. 301: 1033-41. PMID 12023535 DOI: 10.1124/jpet.301.3.1033 |
0.615 |
|
| 2001 |
Christopoulos A, Grant MKO, Ayoubzadeh N, Kim ON, Sauerberg P, Jeppesen L, El-Fakahany EE. Synthesis and pharmacological evaluation of dimeric muscarinic acetylcholine receptor agonists Journal of Pharmacology and Experimental Therapeutics. 298: 1260-1268. PMID 11504829 |
0.488 |
|
| 2000 |
Christopoulos A, Grant MKO, El-Fakahany EE. Transducer abstraction - A novel approach to the detection of partial agonist efficacy in radioligand binding studies Journal of Pharmacological and Toxicological Methods. 43: 55-67. PMID 11091130 DOI: 10.1016/S1056-8719(00)00078-2 |
0.568 |
|
| 2000 |
Waid DK, Chell M, El-Fakahany EE. M2 and M4 muscarinic receptor subtypes couple to activation of endothelial nitric oxide synthase Pharmacology. 61: 37-42. PMID 10895079 |
0.423 |
|
| 2000 |
Linden DR, Chell MJ, El-Fakahany EE, Seybold VS. Neurokinin3 receptors couple to the activation of neuronal nitric-oxide synthase in stably transfected Chinese hamster ovary cells Journal of Pharmacology and Experimental Therapeutics. 293: 559-568. PMID 10773029 |
0.363 |
|
| 2000 |
Jakubík J, El-Fakahany EE, Tuček S. Evidence for a tandem two-site model of ligand binding to muscarinic acetylcholine receptors Journal of Biological Chemistry. 275: 18836-18844. PMID 10749854 DOI: 10.1074/jbc.M000112200 |
0.553 |
|
| 2000 |
Carriere JL, El-Fakahany EE. Choline is a full agonist in inducing activation of neuronal nitric oxide synthase via the muscarinic M1 receptor Pharmacology. 60: 82-89. PMID 10657757 |
0.377 |
|
| 2000 |
Akici A, Karaalp A, Iskender E, Christopoulos A, El-Fakahany EE, Oktay S. Further evidence for the heterogeneity of functional muscarinic receptors in guinea pig gallbladder European Journal of Pharmacology. 388: 115-123. PMID 10657554 DOI: 10.1016/S0014-2999(99)00832-8 |
0.4 |
|
| 1999 |
Christopoulos A, Parsons AM, Lew MJ, El-Fakahany EE. The assessment of antagonist potency under conditions of transient response kinetics European Journal of Pharmacology. 382: 217-227. PMID 10556673 DOI: 10.1016/S0014-2999(99)00550-6 |
0.507 |
|
| 1999 |
Akici A, Karaalp A, Iskender E, El-Fakahany EE, Oktay S. Muscarinic M2 receptors are not primarily involved in the contraction of guinea-pig gallbladder smooth muscle Pharmacological Research. 40: 443-449. PMID 10527660 DOI: 10.1006/phrs.1999.0536 |
0.529 |
|
| 1999 |
Grant MKO, Christopoulos A, El-Fakahany EE. Regulation of acetylcholine binding by ATP at the muscarinic M1 receptor in intact CHO cells Brain Research. 839: 94-99. PMID 10482803 DOI: 10.1016/S0006-8993(99)01720-5 |
0.537 |
|
| 1999 |
Christopoulos A, El-Fakahany EE. Qualitative and quantitative assessment of relative agonist efficacy Biochemical Pharmacology. 58: 735-748. PMID 10449182 DOI: 10.1016/S0006-2952(99)00087-8 |
0.413 |
|
| 1999 |
Michal P, Lysíková M, El-Fakahany EE, Tuček S. Clozapine interaction with the M2 and M4 subtypes of muscarinic receptors European Journal of Pharmacology. 376: 119-125. PMID 10440097 DOI: 10.1016/S0014-2999(99)00341-6 |
0.573 |
|
| 1999 |
Christopoulos A, Parsons AM, El-Fakahany EE. Pharmacological analysis of the novel mode of interaction between xanomeline and the M1 muscarinic acetylcholine receptor Journal of Pharmacology and Experimental Therapeutics. 289: 1220-1228. PMID 10336509 |
0.483 |
|
| 1999 |
Parsons AM, Sorman JL, El-Fakahany EE. Regulation of M1 muscarinic receptor-mediated signaling in intact cells by exogenous, but not endogenously produced, nitric oxide Neurochemical Research. 24: 85-94. PMID 9973241 DOI: 10.1023/A:1020936231662 |
0.373 |
|
| 1999 |
Christopoulos A, Sorman JL, Mitchelson F, El-Fakahany EE. Characterization of the subtype selectivity of the allosteric modulator heptane-1,7-bis-(dimethyl-3'-phthalimidopropyl) ammonium bromide (c7/3-phth) at cloned muscarinic acetylcholine receptors Biochemical Pharmacology. 57: 171-179. PMID 9890565 DOI: 10.1016/S0006-2952(98)00277-9 |
0.567 |
|
| 1999 |
Cuadra A, El-Fakahany E. Investigating the mechanisms of upregulation of neuronal nitric oxide synthase (nNOS) by the muscarinic M1 receptor Life Sciences. 64: 573. DOI: 10.1016/S0024-3205(99)90501-5 |
0.336 |
|
| 1998 |
Tuček S, Jakubík J, Doležal V, El-Fakahany EE. Positive effects of allosteric modulators on the binding properties and the function of muscarinic acetylcholine receptors Journal of Physiology Paris. 92: 241-243. PMID 9789816 DOI: 10.1016/S0928-4257(98)80026-0 |
0.548 |
|
| 1998 |
Oktay S, Cabadak H, Iskender E, Gören Z, Calişkan E, Orun O, Aslan N, Karaalp A, Tolun A, Ulusoy NB, Levey AI, El-Fakahany EE, Kan B. Evidence for the presence of muscarinic M2 and M4 receptors in guinea-pig gallbladder smooth muscle. Journal of Autonomic Pharmacology. 18: 195-204. PMID 9788289 DOI: 10.1046/j.1365-2680.1998.18474.x |
0.476 |
|
| 1998 |
Cuadra AE, El-Fakahany EE. Up-regulation of the neuronal form of nitric oxide synthase in response to prolonged muscarinic M1 receptor stimulation Journal of Neurochemistry. 71: 571-579. PMID 9681447 |
0.578 |
|
| 1998 |
Wotta DR, Parsons AM, Hu J, Grande AW, El-Fakahany EE. M1 muscarinic receptors stimulate rapid and prolonged phases of neuronal nitric oxide synthase activity: Involvement of different calcium pools Journal of Neurochemistry. 71: 487-497. PMID 9681438 |
0.429 |
|
| 1998 |
Christopoulos A, Pierce TL, Sorman JL, El-Fakahany EE. On the unique binding and activating properties of xanomeline at the M1 muscarinic acetylcholine receptor Molecular Pharmacology. 53: 1120-1130. PMID 9614217 |
0.596 |
|
| 1998 |
Wotta DR, Wattenberg EV, Langason RB, El-Fakahany EE. M1, M3 and M5 muscarinic receptors stimulate mitogen-activated protein kinase Pharmacology. 56: 175-186. PMID 9566019 DOI: 10.1159/000028196 |
0.411 |
|
| 1997 |
Christopoulos A, El-Fakahany EE. Novel persistent activation of muscarinic M1 receptors by xanomeline European Journal of Pharmacology. 334: R3-R4. PMID 9346340 DOI: 10.1016/S0014-2999(97)01162-X |
0.555 |
|
| 1997 |
Cuadra AE, El-Fakahany EE. Enhancement of maximal activation of neuronal nitric oxide synthase at muscarinic M1 receptors following prolonged agonist treatment European Journal of Pharmacology. 334: 107-110. PMID 9346336 DOI: 10.1016/S0014-2999(97)01164-3 |
0.473 |
|
| 1997 |
Wang SZ, Lee SY, Zhu SZ, Wotta DR, Parsons AM, el-Fakahany EE. Activation of neuronal nitric oxide synthase by M2 muscarinic receptors associated with a small increase in intracellular calcium. Pharmacology. 55: 10-7. PMID 9309796 |
0.354 |
|
| 1997 |
Jakubík J, Bačáková L, El-Fakahany EE, Tuček S. Positive cooperativity of acetylcholine and other agonists with allosteric ligands on muscarinic acetylcholine receptors Molecular Pharmacology. 52: 172-179. PMID 9224827 |
0.573 |
|
| 1997 |
Wotta DR, El-Fakahany EE. Muscarinic receptor-mediated activation of nitric oxide synthase Drug Development Research. 40: 205-214. DOI: 10.1002/(SICI)1098-2299(199702)40:2<205::AID-DDR10>3.0.CO;2-K |
0.372 |
|
| 1996 |
Wang SZ, Lee SY, Zhu SZ, el-Fakahany EE. Differential coupling of m1, m3, and m5 muscarinic receptors to activation of neuronal nitric oxide synthase. Pharmacology. 53: 271-80. PMID 8990485 |
0.477 |
|
| 1996 |
Lee SY, Zhu SZ, el-Fakahany EE. Role of two highly conserved tyrosine residues in the m1 muscarinic receptor second transmembrane domain in ligand binding and receptor function Receptors & Signal Transduction. 6: 43-52. PMID 8933621 |
0.556 |
|
| 1996 |
Wang SZ, Edmundson R, Zhu SZ, El-Fakahany EE. Selective enhancement of antagonist ligand binding at muscarinic M2 receptors by heparin due to receptor uncoupling European Journal of Pharmacology. 296: 113-118. PMID 8720484 DOI: 10.1016/0014-2999(95)00674-5 |
0.628 |
|
| 1996 |
Jakubík J, Bačáková L, Lisá V, El-Fakahany EE, Tuček S. Activation of muscarinic acetylcholine receptors via their allosteric binding sites Proceedings of the National Academy of Sciences of the United States of America. 93: 8705-8709. PMID 8710935 DOI: 10.1073/pnas.93.16.8705 |
0.644 |
|
| 1995 |
Hejnová L, Tuček S, El-Fakahany EE. Positive and negative allosteric interactions on muscarinic receptors European Journal of Pharmacology: Molecular Pharmacology. 291: 427-430. PMID 8719429 DOI: 10.1016/0922-4106(95)90085-3 |
0.444 |
|
| 1995 |
Zhu SZ, Lee SY, Wang SZ, el-Fakahany EE. Investigation of the role of an amino acid triplet repeat in differentiating drug-receptor interaction at m1 and m2 muscarinic receptors. Pharmacology. 51: 298-307. PMID 8584581 DOI: 10.1159/000139339 |
0.557 |
|
| 1995 |
Parsons AM, El-Fakahany EE, Seybold VS. Tachykinins alter inositol phosphate formation, but not cyclic AMP levels, in primary cultures of neonatal rat spinal neurons through activation of neurokinin receptors Neuroscience. 68: 855-865. PMID 8577379 DOI: 10.1016/0306-4522(95)00140-E |
0.435 |
|
| 1995 |
Jakubík J, Bačáková L, El-Fakahany EE, Tuček S. Constitutive activity of the M1-M4 subtypes of muscarinic receptors in transfected CHO cells and of muscarinic receptors in the heart cells revealed by negative antagonists Febs Letters. 377: 275-279. PMID 8543067 DOI: 10.1016/0014-5793(95)01360-1 |
0.519 |
|
| 1995 |
Hu J, Wang SZ, Scapecchi S, Gualtieri F, El-Fakahany EE. Cardioselective derivatives of 2, 2-Diphenyl-2-ethylthioacetate do not discriminate between m2 and m3 muscarinic receptors expressed in CHO cells Pharmacology. 50: 273-285. PMID 7667389 DOI: 10.1159/000139293 |
0.596 |
|
| 1995 |
Jakubik J, Bacakova L, El-Fakahany EE, Tucek S. Subtype selectivity of the positive allosteric action of alcuronium at cloned M1-M5 muscarinic acetylcholine receptors Journal of Pharmacology and Experimental Therapeutics. 274: 1077-1083. PMID 7562472 |
0.579 |
|
| 1995 |
Shou Zhen Wang, Sheng Zu Zhu, El-Fakahany EE. Expression of endogenous muscarinic acetylcholine receptors in Chinese hamster ovary cells European Journal of Pharmacology: Molecular Pharmacology. 291: R1-R2. DOI: 10.1016/0922-4106(95)90148-5 |
0.45 |
|
| 1994 |
Zhu SZ, Wang SZ, Hu J, El-Fakahany EE. An arginine residue conserved in most G protein-coupled receptors is essential for the function of the m1 muscarinic receptor Molecular Pharmacology. 45: 517-523. PMID 8145736 |
0.572 |
|
| 1994 |
Shou Zhen Wang, Sheng Zu Zhu, El-Fakahany EE. Efficient coupling of m5 muscarinic acetylcholine receptors to activation of nitric oxide synthase Journal of Pharmacology and Experimental Therapeutics. 268: 552-557. PMID 7509388 |
0.471 |
|
| 1993 |
Kiefer-Day J, Abdallah ESAM, Forray C, Lee NH, Kim ON, El-Fakahany EE. Effects of tacrine on brain muscarinic-receptor-mediated second-messenger signals Pharmacology. 47: 98-110. PMID 8395061 DOI: 10.1159/000139084 |
0.654 |
|
| 1993 |
Hu J, El-Fakahany EE. Role of intercellular and intracellular communication by nitric oxide in coupling of muscarinic receptors to activation of guanylate cyclase in neuronal cells Journal of Neurochemistry. 61: 578-585. PMID 8101558 |
0.388 |
|
| 1993 |
Wang SZ, El-Fakahany EE. Application of transfected cell lines in studies of functional receptor subtype selectivity of muscarinic agonists Journal of Pharmacology and Experimental Therapeutics. 266: 237-243. PMID 7687290 |
0.512 |
|
| 1993 |
Hu J, El-Fakahany EE. Allosteric interaction of dynorphin and myelin basic protein with muscarinic receptors Pharmacology. 47: 351-359. PMID 7506424 |
0.457 |
|
| 1992 |
Lee NH, Hu J, El-Fakahany EE. Modulation by certain conserved aspartate residues of the allosteric interaction of gallamine at the m1 muscarinic receptor Journal of Pharmacology and Experimental Therapeutics. 262: 312-316. PMID 1625205 |
0.556 |
|
| 1992 |
Hu J, Wang SZ, Forray C, El-Fakahany EE. Complex allosteric modulation of cardiac muscarinic receptors by protamine: Potential model for putative endogenous ligands Molecular Pharmacology. 42: 311-321. PMID 1513329 |
0.618 |
|
| 1992 |
Wang SZ, Zhu SZ, Joseph JA, el-Fakahany EE. Comparison of the level of mRNA encoding m1 and m2 muscarinic receptors in brains of young and aged rats. Neuroscience Letters. 145: 149-52. PMID 1465211 DOI: 10.1016/0304-3940(92)90008-U |
0.498 |
|
| 1992 |
Wang SZ, Zhu SZ, Mash DC, El-Fakahany EE. Comparison of the concentration of messenger RNA encoding four muscarinic receptor subtypes in control and Alzheimer brains Molecular Brain Research. 16: 64-70. PMID 1334201 DOI: 10.1016/0169-328X(92)90194-G |
0.398 |
|
| 1992 |
Mohamed AS, Forray C, Aly MH, el-Fakahany EE. Lack of intrinsic activity and significant subtype selectivity of SR 95639A at muscarinic receptors. European Journal of Pharmacology. 227: 181-7. PMID 1330650 DOI: 10.1016/0922-4106(92)90126-G |
0.595 |
|
| 1992 |
Kiefer-Day JS, El-Fakahany EE. Muscarinic receptor function and acetylcholinesterase activity after chronic administration of tacrine to mice at therapeutic drug concentrations Pharmacology. 44: 71-80. PMID 1315062 DOI: 10.1159/000138875 |
0.508 |
|
| 1991 |
Zhu SZ, Wang SZ, Abdallah EAM, El-Fakahany EE. DFP-induced regulation of cardiac muscarinic receptor mRNA in vivo measured by DNA-excess solution hybridization Life Sciences. 48: 2579-2584. PMID 2046480 DOI: 10.1016/0024-3205(91)90615-I |
0.501 |
|
| 1991 |
Lee NH, El-Fakahany EE. Allosteric interactions at the m1, m2 and m3 muscarinic receptor subtypes Journal of Pharmacology and Experimental Therapeutics. 256: 468-479. PMID 1993991 |
0.529 |
|
| 1991 |
Lee NH, El-Fakahany EE. Allosteric antagonists of the muscarinic acetylcholine receptor Biochemical Pharmacology. 42: 199-205. PMID 1859442 DOI: 10.1016/0006-2952(91)90703-8 |
0.733 |
|
| 1991 |
Kiefer-Day JS, Campbell HE, Towles J, El-Fakahany EE. Muscarinic subtype selectivity of tetrahydroaminoacridine: Possible relationship to its capricious efficacy European Journal of Pharmacology. 203: 421-423. PMID 1773827 DOI: 10.1016/0014-2999(91)90901-2 |
0.595 |
|
| 1991 |
Fernando JCR, Abdallah ESAM, Evinger M, Forray C, El-Fakahany EE. The presence of an M4 subtype muscarinic receptor in the bovine adrenal medulla revealed by mRNA and receptor binding analyses European Journal of Pharmacology: Molecular Pharmacology. 207: 297-303. PMID 1723686 DOI: 10.1016/0922-4106(91)90003-Z |
0.628 |
|
| 1991 |
Hu J, Wang SZ, El-Fakahany EE. Effects of agonist efficacy on desensitization of phosphoinositide hydrolysis mediated by m1 and m3 muscarinic receptors expressed in Chinese hamster ovary cells Journal of Pharmacology and Experimental Therapeutics. 257: 938-945. PMID 1710663 |
0.591 |
|
| 1991 |
Abdallah EA, el-Fakahany EE. Lack of desensitization of muscarinic receptor-mediated second messenger signals in rat brain upon acute and chronic inhibition of acetylcholinesterase Journal of Biochemical Toxicology. 6: 261-268. PMID 1663554 |
0.507 |
|
| 1991 |
Jett DA, Abdallah EAM, El-Fakahany EE, Eldefrawi ME, Eldefrawi AT. High-affinity activation by paraoxon of a muscarinic receptor subtype in rat brain striatum Pesticide Biochemistry and Physiology. 39: 149-157. DOI: 10.1016/0048-3575(91)90135-9 |
0.669 |
|
| 1990 |
Fryer AD, El-Fakahany EE. Identification of three muscarinic receptor subtypes in rat lung using binding studies with selective antagonists Life Sciences. 47: 611-618. PMID 2402185 DOI: 10.1016/0024-3205(90)90572-9 |
0.71 |
|
| 1990 |
Lee NH, El-Fakahany EE. The allosteric binding profile of himbacine: a comparison with other cardioselective muscarinic antagonists European Journal of Pharmacology. 179: 225-229. PMID 2364985 DOI: 10.1016/0014-2999(90)90424-5 |
0.708 |
|
| 1990 |
Wang SZ, Hu J, Long RM, Pou WS, Forray C, El-Fakahany EE. Agonist-induced down-regulation of m1 muscarinic receptors and reduction of their mRNA level in a transfected cell line Febs Letters. 276: 185-188. PMID 2265699 DOI: 10.1016/0014-5793(90)80538-T |
0.609 |
|
| 1990 |
Fryer AD, El-Fakahany EE, Jacoby DB. Parainfluenza virus type 1 reduces the affinity of agonists for muscarinic receptors in guinea-pig lung and heart European Journal of Pharmacology. 181: 51-58. PMID 2167230 DOI: 10.1016/0014-2999(90)90244-Z |
0.601 |
|
| 1990 |
Abdallah EAM, Forray C, El-Fakahany EE. Relationship between the partial inhibition of muscarinic receptor-mediated phosphoinositide hydrolysis by phorbol esters and tetrodotoxin in rat cerebral cortex Molecular Brain Research. 8: 1-7. PMID 2166196 DOI: 10.1016/0169-328X(90)90002-U |
0.669 |
|
| 1990 |
Forray C, El-Fakahany EE. On the involvement of multiple muscarinic receptor subtypes in the activation of phosphoinositide metabolism in rat cerebral cortex Molecular Pharmacology. 37: 893-902. PMID 2163015 |
0.563 |
|
| 1990 |
Lai WS, Rogers TB, el-Fakahany EE. Protein kinase C is involved in desensitization of muscarinic receptors induced by phorbol esters but not by receptor agonists. The Biochemical Journal. 267: 23-9. PMID 2158308 DOI: 10.1042/Bj2670023 |
0.635 |
|
| 1990 |
Lai WS, el-Fakahany EE. Antagonism by the diacylglycerol kinase inhibitor R59 022 of muscarinic receptor-mediated cyclic GMP formation and binding of [3H]N-methylscopolamine. Biochemical Pharmacology. 39: 221-2. PMID 2153379 DOI: 10.1016/0006-2952(90)90671-7 |
0.55 |
|
| 1990 |
el-Fakahany EE, Cioffi CL. Molecular mechanisms of regulation of neuronal muscarinic receptor sensitivity. Membrane Biochemistry. 9: 9-27. PMID 2077364 DOI: 10.3109/09687689009026820 |
0.587 |
|
| 1990 |
Pou WS, Pou S, Rosen GM, El-Fakahany EE. EDRF release is a common pathway in the activation of guanylate cyclase by receptor agonists and calcium ionophores European Journal of Pharmacology. 182: 393-394. PMID 1975786 DOI: 10.1016/0014-2999(90)90300-U |
0.489 |
|
| 1990 |
Arroyo CM, Forray C, El-Fakahany EE, Rosen GM. Receptor-mediated generation of an EDRF-like intermediate in a neuronal cell line detected by spin trapping techniques Biochemical and Biophysical Research Communications. 170: 1177-1183. PMID 1975169 DOI: 10.1016/0006-291X(90)90517-Q |
0.341 |
|
| 1990 |
Meng Y, Hu J, El-Fakahany EE. p-fluoro-hexahydro-sila-difenidol exhibits poor selectivity between m3 and m1 muscarinic receptors Molecular Membrane Biology. 9: 293-300. PMID 1967074 DOI: 10.3109/09687689009025848 |
0.552 |
|
| 1990 |
Abdallah EAM, Pou WS, El-Fakahany EE. Aging does not alter muscarinic receptor-mediated inhibition of cyclic AMP formation in the striatum and hippocampus Brain Research. 534: 234-236. PMID 1963561 DOI: 10.1016/0006-8993(90)90133-V |
0.532 |
|
| 1990 |
Silverman HJ, Lee NH, el-Fakahany EE. Effects of canine endotoxin shock on lymphocytic beta-adrenergic receptors. Circulatory Shock. 32: 293-306. PMID 1963122 |
0.303 |
|
| 1990 |
Hu J, El-Fakahany EE. Selectivity of McN-A-343 in stimulating phosphoinositide hydrolysis mediated by M1 muscarinic receptors Molecular Pharmacology. 38: 895-903. PMID 1701216 |
0.516 |
|
| 1989 |
Fryer AD, El-Fakahany EE. An endogenous factor induces heterogeneity of binding sites of selective muscarinic receptor antagonists in rat heart Molecular Membrane Biology. 8: 127-132. PMID 2641948 DOI: 10.3109/09687688909025826 |
0.702 |
|
| 1989 |
Lee NH, Fryer AD, Forray C, El-Fakahany EE. Different mechanisms of antagonism by methoctramine of two neuronal muscarinic receptor-mediated second messenger responses Journal of Pharmacology and Experimental Therapeutics. 251: 992-999. PMID 2557423 |
0.643 |
|
| 1989 |
Lee NH, Forray C, El-Fakahany EE. Methoctramine, a cardioselective muscarinic antagonist, stimulates phosphoinositide hydrolysis in rat cerebral cortex European Journal of Pharmacology. 167: 295-298. PMID 2556288 DOI: 10.1016/0014-2999(89)90591-8 |
0.648 |
|
| 1989 |
Surichamorn W, Abdallah EAM, El-Fakahany EE. Aging does not alter brain muscarinic receptor-mediated phosphoinositide hydrolysis and its inhibition by phorbol esters, tetrodotoxin and receptor desensitization Journal of Pharmacology and Experimental Therapeutics. 251: 543-549. PMID 2553927 |
0.477 |
|
| 1989 |
Lee NH, El-Fakahany EE. Mixed competitive and allosteric antagonism by gallamine of muscarinic receptor-mediated second messenger responses in N1E-115 neuroblastoma cells Journal of Neurochemistry. 53: 1300-1308. PMID 2549200 DOI: 10.1111/J.1471-4159.1989.Tb07428.X |
0.715 |
|
| 1989 |
Surichamorn W, Amrhein CL, Forray C, El-Fakahany EE. Inhibition of cyclic AMP formation in N1E-115 neuroblastoma cells is mediated by a non-cardiac M2 muscarinic receptor subtype Brain Research. 493: 320-325. PMID 2548669 DOI: 10.1016/0006-8993(89)91166-9 |
0.585 |
|
| 1989 |
McKinney M, Anderson D, Forray C, El-Fakahany EE. Characterization of the striatal M2 muscarinic receptor mediating inhibition of cyclic AMP using selective antagonists: A comparison with the brainstem M2 receptor Journal of Pharmacology and Experimental Therapeutics. 250: 565-572. PMID 2547939 |
0.526 |
|
| 1989 |
Cioffi CL, el-Fakahany EE. Differential sensitivity of phosphoinositide and cyclic GMP responses to short-term regulation by a muscarinic agonist in mouse neuroblastoma cells. Correlation with down-regulation of cell surface receptors. Biochemical Pharmacology. 38: 1827-34. PMID 2544180 DOI: 10.1016/0006-2952(89)90418-8 |
0.604 |
|
| 1988 |
Lai WS, el-Fakahany EE. Regulation of [3H]phorbol-12,13-dibutyrate binding sites in mouse neuroblastoma cells: simultaneous down-regulation by phorbol esters and desensitization of their inhibition of muscarinic receptor function. The Journal of Pharmacology and Experimental Therapeutics. 244: 41-50. PMID 3422096 |
0.426 |
|
| 1988 |
Lee NH, El-Fakahany EE. Influence of ligand choice on the apparent binding profile of gallamine to cardiac muscarinic receptors. Identification of three main types of gallamine-muscarinic receptor interactions Journal of Pharmacology and Experimental Therapeutics. 246: 829-838. PMID 3418516 |
0.524 |
|
| 1988 |
Surichamorn W, Kim ON, Lee NH, Lai WS, el-Fakahany EE. Effects of aging on the interaction of quinuclidinyl benzilate, N-methylscopolamine, pirenzepine, and gallamine with brain muscarinic receptors. Neurochemical Research. 13: 1183-91. PMID 3237310 DOI: 10.1007/Bf00971637 |
0.687 |
|
| 1988 |
McKinney M, Lee NH, Anderson DJ, Vella-Rountree L, El-Fakahany EE. Non-selectivity of amitriptyline for subtypes of brain muscarinic receptors demonstrated in binding and functional assays European Journal of Pharmacology. 157: 51-60. PMID 2853074 DOI: 10.1016/0014-2999(88)90470-0 |
0.749 |
|
| 1988 |
Cioffi CL, el-Fakahany EE. Lack of alterations in muscarinic receptor subtypes and phosphoinositide hydrolysis upon acute DFP treatment. European Journal of Pharmacology. 156: 35-45. PMID 2850209 DOI: 10.1016/0014-2999(88)90144-6 |
0.597 |
|
| 1988 |
el-Fakahany EE, Surichamorn W, Amrhein CL, Stenstrom S, Cioffi CL, Richelson E, McKinney M. Pseudo-noncompetitive antagonism of muscarinic receptor-mediated cyclic GMP formation and phosphoinositide hydrolysis by pirenzepine. The Journal of Pharmacology and Experimental Therapeutics. 247: 934-40. PMID 2849677 |
0.555 |
|
| 1988 |
el-Fakahany EE, Alger BE, Lai WS, Pitler TA, Worley PF, Baraban JM. Neuronal muscarinic responses: role of protein kinase C. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 2: 2575-83. PMID 2838363 DOI: 10.1096/Fasebj.2.10.2838363 |
0.353 |
|
| 1988 |
Ramkumar V, El-Fakahany EE. Prolonged morphine treatment increases rat brain dihydropyridine binding sites: possible involvement in development of morphine dependence European Journal of Pharmacology. 146: 73-83. PMID 2832198 DOI: 10.1016/0014-2999(88)90488-8 |
0.377 |
|
| 1988 |
Ramkumar V, El-Fakahany EE. Morphine Treatment Increases [3H]Nimodipine Binding Sites in Rat Brain Annals of the New York Academy of Sciences. 522: 207-209. DOI: 10.1111/J.1749-6632.1988.Tb33357.X |
0.414 |
|
| 1987 |
Lai WS, el-Fakahany EE. Phorbol ester-induced inhibition of cyclic GMP formation mediated by muscarinic receptors in murine neuroblastoma cells. The Journal of Pharmacology and Experimental Therapeutics. 241: 366-73. PMID 3033212 |
0.55 |
|
| 1987 |
Lee JH, El-Fakahany EE. Agonist-induced desensitization of muscarinic acetylcholine receptor in rat brain Archives of Pharmacal Research. 10: 212-218. DOI: 10.1007/Bf02857742 |
0.679 |
|
| 1987 |
Jong-Hwa Lee, El-Fakahany EE. Multiple binding affinities for muscarinic acetylcholine receptors in rat brain Korean Journal of Pharmacology. 23: 101-111. |
0.513 |
|
| 1986 |
Cioffi CL, el-Fakahany EE. Decreased binding of the muscarinic antagonist [3H]N-methylscopolamine in mouse brain following acute treatment with an organophosphate. European Journal of Pharmacology. 132: 147-54. PMID 3816972 DOI: 10.1016/0014-2999(86)90599-6 |
0.508 |
|
| 1986 |
El-Fakahany EE, Lee JH. Agonist-induced muscarinic acetylcholine receptor down-regulation in intact rat brain cells European Journal of Pharmacology. 132: 21-30. PMID 3816962 DOI: 10.1016/0014-2999(86)90004-X |
0.625 |
|
| 1986 |
el-Fakahany EE, Cioffi CL, Abdellatif MM, Miller MM. Competitive interaction of pirenzepine with rat brain muscarinic acetylcholine receptors. European Journal of Pharmacology. 131: 237-47. PMID 3816954 DOI: 10.1016/0014-2999(86)90577-7 |
0.588 |
|
| 1986 |
Lai WS, el-Fakahany EE. A selective effect of protein kinase C activation on pirenzepine high-affinity muscarinic receptors in a neuronal clone. European Journal of Pharmacology. 129: 201-2. PMID 3770074 DOI: 10.1016/0014-2999(86)90356-0 |
0.347 |
|
| 1986 |
el-Fakahany EE, Ramkumar V, Lai WS. Multiple binding affinities of N-methylscopolamine to brain muscarinic acetylcholine receptors: differentiation from M1 and M2 receptor subtypes. The Journal of Pharmacology and Experimental Therapeutics. 238: 554-63. PMID 3755473 |
0.561 |
|
| 1986 |
Cioffi CL, el-Fakahany EE. Short-term desensitization of muscarinic cholinergic receptors in mouse neuroblastoma cells: selective loss of agonist low-affinity and pirenzepine high-affinity binding sites. The Journal of Pharmacology and Experimental Therapeutics. 238: 916-23. PMID 3018226 |
0.639 |
|
| 1986 |
Rogers NF, el-Fakahany E. Morphine-induced opioid receptor down-regulation detected in intact adult rat brain cells. European Journal of Pharmacology. 124: 221-30. PMID 3015639 DOI: 10.1016/0014-2999(86)90223-2 |
0.428 |
|
| 1986 |
Lai WS, el-Fakahany EE. Interaction of 4-aminopyridine with [3H]phencyclidine receptors in rat brain homogenates. Neuroscience Letters. 67: 87-91. PMID 2425297 DOI: 10.1016/0304-3940(86)90214-4 |
0.574 |
|
| 1985 |
Lee JH, El-Fakahany EE. [3H]N-methylscopolamine binding to muscarinic receptors in intact adult rat brain cell aggregates Biochemical Pharmacology. 34: 4299-4303. PMID 4074390 DOI: 10.1016/0006-2952(85)90288-6 |
0.63 |
|
| 1985 |
Lee JH, El-Fakahany EE. Use of intact rat brain cells as a model to study regulation of muscarinic acetylcholine receptors Life Sciences. 37: 515-521. PMID 4021726 DOI: 10.1016/0024-3205(85)90463-1 |
0.614 |
|
| 1985 |
Lee JH, El-Fakahany EE. Anomalous binding of [3H]N-methylscopolamine to rat brain muscarinic receptors European Journal of Pharmacology. 110: 263-266. PMID 3987816 DOI: 10.1016/0014-2999(85)90221-3 |
0.523 |
|
| 1985 |
Feigenbaum P, El-Fakahany EE. Regulation of muscarinic cholinergic receptor density in neuroblastoma cells by brief exposure to agonist: Possible involvement in desensitization of receptor function Journal of Pharmacology and Experimental Therapeutics. 233: 134-140. PMID 3981451 |
0.566 |
|
| 1985 |
Lee JH, El-Fakahany EE. Heterogeneity of binding of muscarinic receptor antagonists in rat brain homogenates Journal of Pharmacology and Experimental Therapeutics. 233: 707-714. PMID 3839264 |
0.634 |
|
| 1985 |
Rogers NF, el-Fakahany EE. Intact brain cells: a novel model system for studying opioid receptor binding. Life Sciences. 37: 307-14. PMID 2989648 DOI: 10.1016/0024-3205(85)90500-4 |
0.488 |
|
| 1985 |
Khazan N, Young GA, El-Fakahany EE, Hong O, Calligaro D. Sigma opioid receptor; SKF-10,047 update Neuropeptides. 5: 339-340. PMID 2987734 DOI: 10.1016/0143-4179(85)90022-8 |
0.381 |
|
| 1985 |
Lai WS, Ramkumar V, el-Fakahany EE. Possible allosteric interaction of 4-aminopyridine with rat brain muscarinic acetylcholine receptors. Journal of Neurochemistry. 44: 1936-42. PMID 2580955 |
0.507 |
|
| 1985 |
El-Fakahany EE. Additional complexities in the binding of muscarinic receptor antagonists Trends in Pharmacological Sciences. 6: 430-431. DOI: 10.1016/0165-6147(85)90204-4 |
0.56 |
|
| 1985 |
Rogers NF, El-Fakahany EE. Opioid receptor binding to intact brain cells Federation Proceedings. 44: No. 1165. |
0.375 |
|
| 1984 |
Feigenbaum P, El-Fakahany EE. Short-term regulation of muscarinic acetylcholine receptor binding in cultured nerve cells Research Communications in Chemical Pathology and Pharmacology. 43: 519-522. PMID 6718813 |
0.533 |
|
| 1984 |
El-Fakahany EE, Eldefrawi AT, Murphy DL, Aguayo LG, Triggle DJ, Albuquerque EX, Eldefrawi ME. Interactions of phencyclidine with crayfish muscle membranes. Sensitivity to calcium channel antagonists and other drugs. Molecular Pharmacology. 25: 369-78. PMID 6328263 |
0.317 |
|
| 1984 |
El-Fakahany EE, Triggle DJ, Eldefrawi AT, Eldefrawi ME. Distinction between high-affinity [3H]phencyclidine binding sites and muscarinic receptors in guinea-pig ileum muscle. The Journal of Pharmacology and Experimental Therapeutics. 229: 447-54. PMID 6325665 |
0.477 |
|
| 1984 |
El-Fakahany EE, Pfenning M, Richelson E. Kinetic effects of terbium ions on muscarinic acetylcholine receptors of murine neuroblastoma cells Journal of Neurochemistry. 42: 863-869. PMID 6319610 |
0.574 |
|
| 1984 |
Ramkumar V, El-Fakahany EE. Increase in [3H]nitrendipine binding sites in the brain in morphine-tolerant mice European Journal of Pharmacology. 102: 371-372. PMID 6090166 DOI: 10.1016/0014-2999(84)90272-3 |
0.385 |
|
| 1984 |
Feigenbaum P, El-Fakahany EE. Short-term regulation of muscarinic acetylcholine receptor density in cultured nerve cells Federation Proceedings. 43: no. 3426. |
0.312 |
|
| 1984 |
Ramkumar V, El-Fakahany EE, Roffman DS. The effect of intermittent dobutamine infusion on beta-adrenergic receptors in human lymphocytes Federation Proceedings. 43: no. 412. |
0.305 |
|
| 1984 |
Rogers NP, Hong O, El-Fakahany EE. Ethylketocyclazocide interaction with the MU opioid receptor Federation Proceedings. 43: no. 2377. |
0.324 |
|
| 1982 |
Richelson E, El-Fakahany E. Changes in the sensitivity of receptors for neurotransmitters and the actions of some psychotherapeutic drugs Mayo Clinic Proceedings. 57: 576-582. PMID 6125630 |
0.334 |
|
| 1981 |
El-Fakahany E, Richelson E. Phenoxybenzamine and dibenamine interactions with calcium channel effectors of the muscarinic receptor Molecular Pharmacology. 20: 519-525. PMID 6276712 |
0.531 |
|
| 1981 |
Richelso E, El-Fakahany E. The molecular basis of neurotransmission at the muscarinic receptor Biochemical Pharmacology. 30: 2887-2891. PMID 6274353 DOI: 10.1016/0006-2952(81)90248-3 |
0.471 |
|
| 1981 |
El-Fakahany E, Richelson E. Effects of lanthanides on muscarinic acetylcholine receptor function Molecular Pharmacology. 19: 282-290. PMID 6262619 |
0.514 |
|
| 1980 |
El-Fakahany E, Richelson E. Temperature dependence of muscarinic acetylcholine receptor activation, desensitization, and resensitization Journal of Neurochemistry. 34: 1288-1295. PMID 6246206 |
0.416 |
|
| 1980 |
El-Fakahany E, Richelson E. Regulation of muscarinic receptor-mediated cyclic GMP synthesis by cultured mouse neuroblastoma cells Journal of Neurochemistry. 35: 941-948. PMID 6109003 |
0.388 |
|
| 1979 |
Taylor JE, El-Fakahany E, Richelson E. Long-term regulation of muscarinic acetylcholine receptors on cultured nerve cells Life Sciences. 25: 2181-2187. PMID 232208 DOI: 10.1016/0024-3205(79)90090-0 |
0.481 |
|
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