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Patricia A. Leake - Publications

Affiliations: 
Bioengineering University of California, Berkeley, Berkeley, CA, United States 
Area:
Biomedical Engineering, Electronics and Electrical Engineering
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52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Leake PA, Akil O, Lang H. Neurotrophin gene therapy to promote survival of spiral ganglion neurons after deafness. Hearing Research. 107955. PMID 32331858 DOI: 10.1016/J.Heares.2020.107955  0.362
2019 Leake PA, Rebscher SJ, Dore' C, Akil O. AAV-Mediated Neurotrophin Gene Therapy Promotes Improved Survival of Cochlear Spiral Ganglion Neurons in Neonatally Deafened Cats: Comparison of AAV2-hBDNF and AAV5-hGDNF. Journal of the Association For Research in Otolaryngology : Jaro. PMID 31222416 DOI: 10.1007/S10162-019-00723-5  0.38
2018 Akil O, Blits B, Lustig LR, Leake PA. Virally Mediated Overexpression of Glial-Derived Neurotrophic Factor Elicits Age- and Dose-Dependent Neuronal Toxicity and Hearing Loss. Human Gene Therapy. PMID 30183384 DOI: 10.1089/Hum.2018.028  0.37
2016 Kandathil CK, Stakhovskaya O, Leake PA. Effects of brain-derived neurotrophic factor (BDNF) on the cochlear nucleus in cats deafened as neonates. Hearing Research. PMID 27773647 DOI: 10.1016/J.Heares.2016.10.011  0.455
2016 Vollmer M, Beitel RE, Schreiner CE, Leake PA. Passive stimulation and behavioral training differentially transform temporal processing in the inferior colliculus and primary auditory cortex. Journal of Neurophysiology. jn.00392.2016. PMID 27733594 DOI: 10.1152/Jn.00392.2016  0.424
2013 Leake PA, Stakhovskaya O, Hetherington A, Rebscher SJ, Bonham B. Effects of brain-derived neurotrophic factor (BDNF) and electrical stimulation on survival and function of cochlear spiral ganglion neurons in deafened, developing cats. Journal of the Association For Research in Otolaryngology : Jaro. 14: 187-211. PMID 23392612 DOI: 10.1007/S10162-013-0372-5  0.455
2012 Schoenecker MC, Bonham BH, Stakhovskaya OA, Snyder RL, Leake PA. Monopolar intracochlear pulse trains selectively activate the inferior colliculus. Journal of the Association For Research in Otolaryngology : Jaro. 13: 655-72. PMID 22722899 DOI: 10.1007/S10162-012-0333-4  0.557
2011 Leake PA, Hradek GT, Hetherington AM, Stakhovskaya O. Brain-derived neurotrophic factor promotes cochlear spiral ganglion cell survival and function in deafened, developing cats. The Journal of Comparative Neurology. 519: 1526-45. PMID 21452221 DOI: 10.1002/Cne.22582  0.444
2010 Verbist BM, Skinner MW, Cohen LT, Leake PA, James C, Boëx C, Holden TA, Finley CC, Roland PS, Roland JT, Haller M, Patrick JF, Jolly CN, Faltys MA, Briaire JJ, et al. Consensus panel on a cochlear coordinate system applicable in histologic, physiologic, and radiologic studies of the human cochlea. Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 31: 722-30. PMID 20147866 DOI: 10.1097/Mao.0B013E3181D279E0  0.386
2008 Rebscher SJ, Hetherington A, Bonham B, Wardrop P, Whinney D, Leake PA. Considerations for design of future cochlear implant electrode arrays: electrode array stiffness, size, and depth of insertion. Journal of Rehabilitation Research and Development. 45: 731-47. PMID 18816423 DOI: 10.1682/Jrrd.2007.08.0119  0.437
2008 Stakhovskaya O, Hradek GT, Snyder RL, Leake PA. Effects of age at onset of deafness and electrical stimulation on the developing cochlear nucleus in cats. Hearing Research. 243: 69-77. PMID 18590947 DOI: 10.1016/J.Heares.2008.05.007  0.484
2008 Leake PA, Hradek GT, Bonham BH, Snyder RL. Topography of auditory nerve projections to the cochlear nucleus in cats after neonatal deafness and electrical stimulation by a cochlear implant. Journal of the Association For Research in Otolaryngology : Jaro. 9: 349-72. PMID 18574634 DOI: 10.1007/S10162-008-0127-X  0.482
2008 Leake PA, Stakhovskaya O, Hradek GT, Hetherington AM. Factors influencing neurotrophic effects of electrical stimulation in the deafened developing auditory system. Hearing Research. 242: 86-99. PMID 18573324 DOI: 10.1016/J.Heares.2008.06.002  0.546
2007 Vollmer M, Beitel RE, Snyder RL, Leake PA. Spatial selectivity to intracochlear electrical stimulation in the inferior colliculus is degraded after long-term deafness in cats. Journal of Neurophysiology. 98: 2588-603. PMID 17855592 DOI: 10.1152/Jn.00011.2007  0.519
2007 Rebscher SJ, Hetherington AM, Snyder RL, Leake PA, Bonham BH. Design and fabrication of multichannel cochlear implants for animal research. Journal of Neuroscience Methods. 166: 1-12. PMID 17727956 DOI: 10.1016/J.Jneumeth.2007.05.013  0.453
2007 Jones TA, Leake PA, Snyder RL, Stakhovskaya O, Bonham B. Spontaneous discharge patterns in cochlear spiral ganglion cells before the onset of hearing in cats. Journal of Neurophysiology. 98: 1898-908. PMID 17686914 DOI: 10.1152/Jn.00472.2007  0.449
2007 Stakhovskaya O, Sridhar D, Bonham BH, Leake PA. Frequency map for the human cochlear spiral ganglion: implications for cochlear implants. Journal of the Association For Research in Otolaryngology : Jaro. 8: 220-33. PMID 17318276 DOI: 10.1007/S10162-007-0076-9  0.328
2007 Leake PA, Hradek GT, Vollmer M, Rebscher SJ. Neurotrophic effects of GM1 ganglioside and electrical stimulation on cochlear spiral ganglion neurons in cats deafened as neonates. The Journal of Comparative Neurology. 501: 837-53. PMID 17311311 DOI: 10.1002/Cne.21275  0.501
2006 Sridhar D, Stakhovskaya O, Leake PA. A frequency-position function for the human cochlear spiral ganglion. Audiology & Neuro-Otology. 11: 16-20. PMID 17063006 DOI: 10.1159/000095609  0.384
2006 Leake PA, Hradek GT, Chair L, Snyder RL. Neonatal deafness results in degraded topographic specificity of auditory nerve projections to the cochlear nucleus in cats. The Journal of Comparative Neurology. 497: 13-31. PMID 16680765 DOI: 10.1002/Cne.20968  0.385
2005 Wardrop P, Whinney D, Rebscher SJ, Luxford W, Leake P. A temporal bone study of insertion trauma and intracochlear position of cochlear implant electrodes. II: Comparison of Spiral Clarion and HiFocus II electrodes. Hearing Research. 203: 68-79. PMID 15855031 DOI: 10.1016/J.Heares.2004.11.007  0.377
2005 Wardrop P, Whinney D, Rebscher SJ, Roland JT, Luxford W, Leake PA. A temporal bone study of insertion trauma and intracochlear position of cochlear implant electrodes. I: Comparison of Nucleus banded and Nucleus Contour electrodes. Hearing Research. 203: 54-67. PMID 15855030 DOI: 10.1016/J.Heares.2004.11.006  0.411
2005 Vollmer M, Leake PA, Beitel RE, Rebscher SJ, Snyder RL. Degradation of temporal resolution in the auditory midbrain after prolonged deafness is reversed by electrical stimulation of the cochlea. Journal of Neurophysiology. 93: 3339-55. PMID 15659529 DOI: 10.1152/Jn.00900.2004  0.53
2002 Leake PA, Snyder RL, Hradek GT. Postnatal refinement of auditory nerve projections to the cochlear nucleus in cats. The Journal of Comparative Neurology. 448: 6-27. PMID 12012373 DOI: 10.1002/Cne.10176  0.399
2002 Moore CM, Vollmer M, Leake PA, Snyder RL, Rebscher SJ. The effects of chronic intracochlear electrical stimulation on inferior colliculus spatial representation in adult deafened cats. Hearing Research. 164: 82-96. PMID 11950528 DOI: 10.1016/S0378-5955(01)00415-4  0.487
2001 Osofsky MR, Moore CM, Leake PA. Does exogenous GM1 ganglioside enhance the effects of electrical stimulation in ameliorating degeneration after neonatal deafness? Hearing Research. 159: 23-35. PMID 11520632 DOI: 10.1016/S0378-5955(01)00311-2  0.472
2001 Rebscher SJ, Snyder RL, Leake PA. The effect of electrode configuration and duration of deafness on threshold and selectivity of responses to intracochlear electrical stimulation Journal of the Acoustical Society of America. 109: 2035-2048. PMID 11386556 DOI: 10.1121/1.1365115  0.465
2000 Leake PA, Snyder RL, Rebscher SJ, Moore CM, Vollmer M. Plasticity in central representations in the inferior colliculus induced by chronic single- vs. two-channel electrical stimulation by a cochlear implant after neonatal deafness. Hearing Research. 147: 221-41. PMID 10962187 DOI: 10.1016/S0378-5955(00)00133-7  0.469
2000 Snyder RL, Vollmer M, Moore CM, Rebscher SJ, Leake PA, Beitel RE. Responses of inferior colliculus neurons to amplitude-modulated intracochlear electrical pulses in deaf cats. Journal of Neurophysiology. 84: 166-83. PMID 10899194 DOI: 10.1152/Jn.2000.84.1.166  0.424
2000 Beitel RE, Snyder RL, Schreiner CE, Raggio MW, Leake PA. Electrical cochlear stimulation in the deaf cat: comparisons between psychophysical and central auditory neuronal thresholds. Journal of Neurophysiology. 83: 2145-62. PMID 10758124 DOI: 10.1152/Jn.2000.83.4.2145  0.565
2000 Beitel RE, Vollmer M, Snyder RL, Schreiner CE, Leake PA. Behavioral and neurophysiological thresholds for electrical cochlear stimulation in the deaf cat. Audiology & Neuro-Otology. 5: 31-8. PMID 10686430 DOI: 10.1159/000013863  0.471
1999 Vollmer M, Snyder RL, Leake PA, Beitel RE, Moore CM, Rebscher SJ. Temporal properties of chronic cochlear electrical stimulation determine temporal resolution of neurons in cat inferior colliculus. Journal of Neurophysiology. 82: 2883-902. PMID 10601427 DOI: 10.1152/Jn.1999.82.6.2883  0.504
1999 Leake PA, Hradek GT, Snyder RL. Chronic electrical stimulation by a cochlear implant promotes survival of spiral ganglion neurons after neonatal deafness Journal of Comparative Neurology. 412: 543-562. PMID 10464355 DOI: 10.1002/(Sici)1096-9861(19991004)412:4<543::Aid-Cne1>3.0.Co;2-3  0.519
1999 Sato M, Leake PA, Hradek GT. Postnatal development of the organ of Corti in cats: A light microscopic morphometric study Hearing Research. 127: 1-13. PMID 9925011 DOI: 10.1016/S0378-5955(98)00143-9  0.338
1997 Leake PA, Kuntz AL, Moore CM, Chambers PL. Cochlear pathology induced by aminoglycoside ototoxicity during postnatal maturation in cats. Hearing Research. 113: 117-32. PMID 9387991 DOI: 10.1016/S0378-5955(97)00133-0  0.394
1997 Snyder RL, Leake PA. Topography of spiral ganglion projections to cochlear nucleus during postnatal development in cats Journal of Comparative Neurology. 384: 293-311. PMID 9215724 DOI: 10.1002/(Sici)1096-9861(19970728)384:2<293::Aid-Cne9>3.0.Co;2-X  0.428
1997 Snyder RL, Leake PA, Hradek GT. Quantitative analysis of spiral ganglion projections to the cat cochlear nucleus Journal of Comparative Neurology. 379: 133-149. PMID 9057117 DOI: 10.1002/(Sici)1096-9861(19970303)379:1<133::Aid-Cne9>3.0.Co;2-5  0.332
1995 Snyder R, Leake P, Rebscher S, Beitel R. Temporal resolution of neurons in cat inferior colliculus to intracochlear electrical stimulation: effects of neonatal deafening and chronic stimulation. Journal of Neurophysiology. 73: 449-67. PMID 7760111 DOI: 10.1152/Jn.1995.73.2.449  0.536
1995 Leake PA, Snyder RL, Hradek GT, Rebscher SJ. Consequences of chronic extracochlear electrical stimulation in neonatally deafened cats Hearing Research. 82: 65-80. PMID 7744715 DOI: 10.1016/0378-5955(94)00167-O  0.544
1994 Lustig LR, Leake PA, Snyder RL, Rebscher SJ. Changes in the cat cochlear nucleus following neonatal deafening and chronic intracochlear electrical stimulation. Hearing Research. 74: 29-37. PMID 8040097 DOI: 10.1016/0378-5955(94)90173-2  0.52
1993 Leake PA, Snyder RL, Hradek GT. Spatial organization of inner hair cell synapses and cochlear spiral ganglion neurons Journal of Comparative Neurology. 333: 257-270. PMID 8345106 DOI: 10.1002/Cne.903330211  0.356
1992 Leake PA, Snyder RL, Merzenich MM. Topographic organization of the cochlear spiral ganglion demonstrated by restricted lesions of the anteroventral cochlear nucleus. The Journal of Comparative Neurology. 320: 468-78. PMID 1629399 DOI: 10.1002/Cne.903200405  0.377
1992 Leake PA, Snyder RL, Hradek GT, Rebscher SJ. Chronic intracochlear electrical stimulation in neonatally deafened cats: Effects of intensity and stimulating electrode location Hearing Research. 64: 99-117. PMID 1490906 DOI: 10.1016/0378-5955(92)90172-J  0.529
1991 Hultcrantz M, Snyder R, Rebscher S, Leake P. Effects of neonatal deafening and chronic intracochlear electrical stimulation on the cochlear nucleus in cats. Hearing Research. 54: 272-80. PMID 1938629 DOI: 10.1016/0378-5955(91)90121-O  0.517
1991 Leake PA, Hradek GT, Rebscher SJ, Snyder RL. Chronic intracochlear electrical stimulation induces selective survival of spiral ganglion neurons in neonatally deafened cats Hearing Research. 54: 251-271. PMID 1938628 DOI: 10.1016/0378-5955(91)90120-X  0.534
1991 Snyder RL, Rebscher SJ, Leake PA, Kelly K, Cao K. Chronic intracochlear electrical stimulation in the neonatally deafened cat. II: Temporal properties of neurons in the inferior colliculus Hearing Research. 56: 246-264. PMID 1769918 DOI: 10.1016/0378-5955(91)90175-9  0.446
1990 Snyder RL, Rebscher SJ, Cao K, Leake PA, Kelly K. Chronic intracochlear electrical stimulation in the neonatally deafened cat. I: Expansion of central representation Hearing Research. 50: 7-33. PMID 2076984 DOI: 10.1016/0378-5955(90)90030-S  0.534
1989 Jackler RK, Leake PA, Mckerrow WS. Cochlear implant revision: Effects of reimplantation on the cochlea Annals of Otology, Rhinology &Amp; Laryngology. 98: 813-820. PMID 2802465 DOI: 10.1177/000348948909801012  0.301
1989 Leake PA, Snyder RL. Topographic organization of the central projections of the spiral ganglion in cats Journal of Comparative Neurology. 281: 612-629. PMID 2708585 DOI: 10.1002/Cne.902810410  0.343
1989 Zook JM, Leake PA. Connections and frequency representation in the auditory brainstem of the mustache bat, Pteronotus parnellii Journal of Comparative Neurology. 290: 243-261. PMID 2592612 DOI: 10.1002/Cne.902900206  0.39
1988 Leake PA, Hradek GT. Cochlear pathology of long term neomycin induced deafness in cats Hearing Research. 33: 11-33. PMID 3372368 DOI: 10.1016/0378-5955(88)90018-4  0.381
1988 Snyder RL, Leake PA. Intrinsic connections within and between cochlear nucleus subdivisions in cat Journal of Comparative Neurology. 278: 209-225. PMID 3230161 DOI: 10.1002/Cne.902780205  0.32
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