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Kevin J. Hamblett, Ph.D. - Publications

Affiliations: 
2002 University of Washington, Seattle, Seattle, WA 
Area:
Biomedical Engineering, Pharmacy, Radiology, Oncology
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7 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Hamblett KJ, Le T, Rock BM, Rock DA, Siu S, Huard JN, Conner KP, Milburn RR, O Neill JW, Tometsko ME, Fanslow WC. Altering antibody drug conjugate binding to the Neonatal Fc Receptor impacts efficacy and tolerability. Molecular Pharmaceutics. PMID 27248573 DOI: 10.1021/acs.molpharmaceut.6b00153  0.431
2015 Hamblett KJ, Kozlosky CJ, Siu S, Chang WS, Liu H, Foltz IN, Trueblood ES, Meininger D, Arora T, Twomey B, Vonderfecht SL, Chen Q, Hill JS, Fanslow WC. AMG 595, an Anti-EGFRvIII Antibody-Drug Conjugate, Induces Potent Antitumor Activity against EGFRvIII-Expressing Glioblastoma. Molecular Cancer Therapeutics. 14: 1614-24. PMID 25931519 DOI: 10.1158/1535-7163.MCT-14-1078  0.311
2006 McDonagh CF, Turcott E, Westendorf L, Webster JB, Alley SC, Kim K, Andreyka J, Stone I, Hamblett KJ, Francisco JA, Carter P. Engineered antibody-drug conjugates with defined sites and stoichiometries of drug attachment. Protein Engineering, Design & Selection : Peds. 19: 299-307. PMID 16644914 DOI: 10.1093/protein/gzl013  0.357
2005 Sun MM, Beam KS, Cerveny CG, Hamblett KJ, Blackmore RS, Torgov MY, Handley FG, Ihle NC, Senter PD, Alley SC. Reduction-alkylation strategies for the modification of specific monoclonal antibody disulfides. Bioconjugate Chemistry. 16: 1282-90. PMID 16173809 DOI: 10.1021/bc050201y  0.354
2005 Hamblett KJ, Press OW, Meyer DL, Hamlin DK, Axworthy D, Wilbur DS, Stayton PS. Role of biotin-binding affinity in streptavidin-based pretargeted radioimmunotherapy of lymphoma. Bioconjugate Chemistry. 16: 131-8. PMID 15656584 DOI: 10.1021/Bc034049G  0.362
2005 Hamblett KJ, Barton J, Cerveny CG, Andreyka JB, Kissler KM, Okeley NM, Stone I, Sutherland MK, Sun MM, Senter PD, Wahl AF, Ihle NC. SGN-35, an Anti-CD30 Antibody-Drug Conjugate, Exhibits Potent Antitumor Activity for the Treatment of CD30+ Malignancies. Blood. 106: 610-610. DOI: 10.1182/blood.V106.11.610.610  0.33
2002 Hamblett KJ, Kegley BB, Hamlin DK, Chyan MK, Hyre DE, Press OW, Wilbur DS, Stayton PS. A streptavidin-biotin binding system that minimizes blocking by endogenous biotin. Bioconjugate Chemistry. 13: 588-98. PMID 12009950 DOI: 10.1021/Bc010087T  0.362
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