Weiping Han - Publications

Affiliations: 
Singapore Bioimaging Consortium, Singapore, Singapore 
Area:
Metabolic Diseases

104 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lam HY, Arumugam S, Bae HG, Wang CC, Jung S, St John AL, Hong W, Han W, Tergaonkar V. ELKS1 controls mast cell degranulation by regulating the transcription of Stxbp2 and Syntaxin 4 via Kdm2b stabilization. Science Advances. 6. PMID 32937583 DOI: 10.1126/Sciadv.Abb2497  0.341
2020 Chong YC, Toh TB, Chan Z, Lin QXX, Thng DKH, Hooi L, Ding Z, Shuen T, Toh HC, Dan YY, Bonney GK, Zhou L, Chow P, Wang Y, Benoukraf T, ... ... Han W, et al. Targeted Inhibition of Purine Metabolism Is Effective in Suppressing Hepatocellular Carcinoma Progression. Hepatology Communications. 4: 1362-1381. PMID 32923839 DOI: 10.1002/hep4.1559  0.582
2020 Li H, Liu Y, Harvey L, Shafaeizadeh S, van der Beek E, Han W. A mouse model of gestation-specific transient hyperglycemia for translational studies. The Journal of Endocrinology. PMID 31910155 DOI: 10.1530/Joe-19-0516  0.752
2019 Bai B, Yang W, Fu Y, Foon HL, Tay WT, Yang K, Luo C, Gunaratne J, Lee P, Zile MR, Xu A, Chin CWL, Lam CSP, Han W, Wang Y. Seipin Knockout Mice Develop Heart Failure With Preserved Ejection Fraction. Jacc. Basic to Translational Science. 4: 924-937. PMID 31909301 DOI: 10.1016/J.Jacbts.2019.07.008  0.754
2019 Mcilroy GD, Mitchell SE, Han W, Delibegović M, Rochford JJ. Ablation of /Seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy. Disease Models & Mechanisms. PMID 31848133 DOI: 10.1242/Dmm.042655  0.336
2019 Yuan C, Chakraborty S, Chitta KK, Subramanian S, Lim TE, Han W, Bhanu Prakash KN, Sugii S. Fast Adipogenesis Tracking System (FATS)-a robust, high-throughput, automation-ready adipogenesis quantification technique. Stem Cell Research & Therapy. 10: 38. PMID 30670100 DOI: 10.1186/S13287-019-1141-0  0.736
2018 Mcilroy GD, Mitchell SE, Han W, Delibegović M, Rochford JJ. Female adipose tissue-specific Bscl2 knockout mice develop only moderate metabolic dysfunction when housed at thermoneutrality and fed a high-fat diet. Scientific Reports. 8: 17863. PMID 30552349 DOI: 10.1038/S41598-018-36078-9  0.305
2018 Chong YC, Lim TE, Fu Y, Shin EM, Tergaonkar V, Han W. Indian Hedgehog links obesity to development of hepatocellular carcinoma. Oncogene. PMID 30470823 DOI: 10.1038/S41388-018-0585-5  0.743
2018 Luo SX, Huang J, Li Q, Mohammad H, Lee CY, Krishna K, Kok AM, Tan YL, Lim JY, Li H, Yeow LY, Sun J, He M, Grandjean J, Sajikumar S, ... Han W, et al. Regulation of feeding by somatostatin neurons in the tuberal nucleus. Science (New York, N.Y.). 361: 76-81. PMID 29976824 DOI: 10.1126/Science.Aar4983  0.468
2018 Peng X, Zhang Q, Liao C, Han W, Xu F. Epigenomic Control of Thermogenic Adipocyte Differentiation and Function. International Journal of Molecular Sciences. 19. PMID 29914202 DOI: 10.3390/Ijms19061793  0.302
2018 Huang C, Walker EM, Dadi PK, Hu R, Xu Y, Zhang W, Sanavia T, Mun J, Liu J, Nair GG, Tan HYA, Wang S, Magnuson MA, Stoeckert CJ, Hebrok M, ... ... Han W, et al. Synaptotagmin 4 Regulates Pancreatic β Cell Maturation by Modulating the Ca Sensitivity of Insulin Secretion Vesicles. Developmental Cell. PMID 29656931 DOI: 10.1016/J.Devcel.2018.03.013  0.409
2018 Mcilroy GD, Suchacki K, Roelofs AJ, Yang W, Fu Y, Bai B, Wallace RJ, De Bari C, Cawthorn WP, Han W, Delibegović M, Rochford JJ. Adipose specific disruption of seipin causes early-onset generalised lipodystrophy and altered fuel utilisation without severe metabolic disease. Molecular Metabolism. PMID 29459250 DOI: 10.1016/J.Molmet.2018.01.019  0.769
2018 TAN AH, GUN S, HAN W. HOXC10 Maintains White Adipose Tissue Identity and Its Loss Leads to Enhanced Browning of White Adipose Tissues Diabetes. 67: 279-OR. DOI: 10.2337/Db18-279-Or  0.352
2018 Ding Z, Ericksen RE, Steckel M, Haegebarth A, Gruenewald S, Han W. Abstract 3477: Metabolic pathway analyses identify proline biosynthesis as a promoter of liver carcinogenesis Cancer Research. 78: 3477-3477. DOI: 10.1158/1538-7445.Am2018-3477  0.313
2017 Ng R, Hussain NA, Zhang Q, Chang C, Li H, Fu Y, Cao L, Han W, Stunkel W, Xu F. miRNA-32 Drives Brown Fat Thermogenesis and Trans-activates Subcutaneous White Fat Browning in Mice. Cell Reports. 19: 1229-1246. PMID 28494871 DOI: 10.1016/J.Celrep.2017.04.035  0.761
2017 Sim CK, Kim SY, Brunmeir R, Zhang Q, Li H, Dharmasegaran D, Leong C, Lim YY, Han W, Xu F. Regulation of white and brown adipocyte differentiation by RhoGAP DLC1. Plos One. 12: e0174761. PMID 28358928 DOI: 10.1371/Journal.Pone.0174761  0.508
2017 Julien SG, Kim SY, Brunmeir R, Sinnakannu JR, Ge X, Li H, Ma W, Yaligar J, Kn BP, Velan SS, Röder PV, Zhang Q, Sim CK, Wu J, Garcia-Miralles M, ... ... Han W, et al. Narciclasine attenuates diet-induced obesity by promoting oxidative metabolism in skeletal muscle. Plos Biology. 15: e1002597. PMID 28207742 DOI: 10.1371/Journal.Pbio.1002597  0.482
2017 Ng Y, Tan SX, Chia SY, Tan HY, Gun SY, Sun L, Hong W, Han W. HOXC10 suppresses browning of white adipose tissues. Experimental & Molecular Medicine. 49: e292. PMID 28186086 DOI: 10.1038/Emm.2016.144  0.546
2017 Mao L, Nie B, Nie T, Hui X, Gao X, Lin X, Liu X, Xu Y, Tang X, Yuan R, Li K, Li P, Ding K, Wang Y, Xu A, ... ... Han W, et al. Visualization and Quantification of Browning Using a Ucp1-2A-Luciferase Knock-in Mouse Model. Diabetes. 66: 407-417. PMID 28108609 DOI: 10.2337/Db16-0343  0.3
2016 Nie T, Hui X, Mao L, Nie B, Li K, Sun W, Gao X, Tang X, Xu Y, Jiang B, Tu Z, Li P, Ding K, Han W, Zhang S, et al. Harmine Induces Adipocyte Thermogenesis through RAC1-MEK-ERK-CHD4 Axis. Scientific Reports. 6: 36382. PMID 27805061 DOI: 10.1038/Srep36382  0.374
2016 Sorrenson B, Cognard E, Lee KL, Dissanayake WC, Fu Y, Han W, Hughes WE, Shepherd PR. A Critical Role for β-catenin in Modulating Levels of Insulin Secretion from β-cells by Regulating Actin Cytoskeleton and Insulin Vesicle Localization. The Journal of Biological Chemistry. PMID 27777306 DOI: 10.1074/Jbc.M116.758516  0.785
2016 Chen N, Sugihara H, Kim J, Fu Z, Barak B, Sur M, Feng G, Han W. Direct modulation of GFAP-expressing glia in the arcuate nucleus bi-directionally regulates feeding. Elife. 5. PMID 27751234 DOI: 10.7554/Elife.18716  0.764
2016 Ulyanova A, To XV, Asad AB, Han W, Chuang KH. MEMRI detects neuronal activity and connectivity in hypothalamic neural circuit responding to leptin. Neuroimage. PMID 27729278 DOI: 10.1016/J.Neuroimage.2016.10.012  0.334
2016 Liu T, Li H, Hong W, Han W. BIG3 is localized in lysosomes and regulates GABA signaling in hippocampal neurons. Journal of Neurochemistry. PMID 27696409 DOI: 10.1111/Jnc.13859  0.61
2016 Röder PV, Wong X, Hong W, Han W. Molecular regulation of insulin granule biogenesis and exocytosis. The Biochemical Journal. 473: 2737-56. PMID 27621482 DOI: 10.1042/Bcj20160291  0.397
2016 Li H, Kek HC, Lim J, Gelling RW, Han W. Green tea (-)-epigallocatechin-3-gallate counteracts daytime overeating induced by high-fat diet in mice. Molecular Nutrition & Food Research. PMID 27468160 DOI: 10.1002/Mnfr.201600162  0.459
2016 Kim SY, Sim CK, Tang H, Han W, Zhang K, Xu F. Acetylome study in mouse adipocytes identifies targets of SIRT1 deacetylation in chromatin organization and RNA processing. Archives of Biochemistry and Biophysics. PMID 27021582 DOI: 10.1016/J.Abb.2016.03.025  0.333
2016 Röder PV, Wu B, Liu Y, Han W. Pancreatic regulation of glucose homeostasis. Experimental & Molecular Medicine. 48: e219. PMID 26964835 DOI: 10.1038/Emm.2016.6  0.78
2016 Chen N, Sugihara H, Kim J, Fu Z, Barak B, Sur M, Feng G, Han W. Author response: Direct modulation of GFAP-expressing glia in the arcuate nucleus bi-directionally regulates feeding Elife. DOI: 10.7554/Elife.18716.021  0.754
2015 Shi S, Chen S, Han W, Wu B, Zhang X, Tang Y, Wang X, Zhu Y, Peng D, Liu X. Cross-clade protective immune responses of NS1-truncated live attenuated H5N1 avian influenza vaccines. Vaccine. PMID 26638027 DOI: 10.1016/j.vaccine.2015.11.045  0.304
2015 Wang C, Wang Y, Hu M, Chai Z, Wu Q, Huang R, Han W, Zhang CX, Zhou Z. Synaptotagmin-11 inhibits clathrin-mediated and bulk endocytosis. Embo Reports. PMID 26589353 DOI: 10.15252/Embr.201540689  0.522
2015 Yuan Q, Yang F, Xiao Y, Tan S, Husain N, Ren M, Hu Z, Martinowich K, Ng JS, Kim PJ, Han W, Nagata KI, Weinberger DR, Je HS. Regulation of Brain-Derived Neurotrophic Factor Exocytosis and Gamma-Aminobutyric Acidergic Interneuron Synapse by the Schizophrenia Susceptibility Gene Dysbindin-1. Biological Psychiatry. PMID 26386481 DOI: 10.1016/J.Biopsych.2015.08.019  0.598
2015 Lim CY, Hong W, Han W. Adiponectin is released via a unique regulated exocytosis pathway from a pre-formed vesicle pool upon insulin stimulation. The Biochemical Journal. PMID 26330614 DOI: 10.1042/Bj20150301  0.408
2015 Liu Y, Li H, Sugiura Y, Han W, Gallardo G, Khvotchev M, Zhang Y, Kavalali ET, Südhof TC, Lin W. Ubiquitin-Synaptobrevin Fusion Protein Causes Degeneration of Presynaptic Motor Terminals in Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 11514-31. PMID 26290230 DOI: 10.1523/Jneurosci.5288-14.2015  0.595
2015 Wu B, Wei S, Petersen N, Ali Y, Wang X, Bacaj T, Rorsman P, Hong W, Südhof TC, Han W. Synaptotagmin-7 phosphorylation mediates GLP-1-dependent potentiation of insulin secretion from β-cells. Proceedings of the National Academy of Sciences of the United States of America. 112: 9996-10001. PMID 26216970 DOI: 10.1073/Pnas.1513004112  0.794
2015 Qiu B, Shi X, Zhou Q, Chen HS, Lim J, Han W, Tergaonkar V. Hypothalamic NUCKS regulates peripheral glucose homoeostasis. The Biochemical Journal. 469: 391-8. PMID 26205492 DOI: 10.1042/Bj20150450  0.756
2015 Kim SY, Zhang Q, Brunmeir R, Han W, Xu F. SIRT1 Interacts with and Deacetylates ATP6V1B2 in Mature Adipocytes. Plos One. 10: e0133448. PMID 26177453 DOI: 10.1371/Journal.Pone.0133448  0.329
2015 Kee AJ, Yang L, Lucas CA, Greenberg MJ, Martel N, Leong GM, Hughes WE, Cooney GJ, James DE, Ostap EM, Han W, Gunning PW, Hardeman EC. An actin filament population defined by the tropomyosin tpm3.1 regulates glucose uptake. Traffic (Copenhagen, Denmark). 16: 691-711. PMID 25783006 DOI: 10.1111/Tra.12282  0.359
2015 Qiu B, Han W, Tergaonkar V. NUCKS: a potential biomarker in cancer and metabolic disease. Clinical Science (London, England : 1979). 128: 715-21. PMID 25760963 DOI: 10.1042/Cs20140656  0.31
2015 Li H, Liu T, Lim J, Gounko NV, Hong W, Han W. Increased biogenesis of glucagon-containing secretory granules and glucagon secretion in BIG3-knockout mice. Molecular Metabolism. 4: 246-52. PMID 25737957 DOI: 10.1016/J.Molmet.2015.01.001  0.613
2015 Kim JI, Huh JY, Sohn JH, Choe SS, Lee YS, Lim CY, Jo A, Park SB, Han W, Kim JB. Lipid-overloaded enlarged adipocytes provoke insulin resistance independent of inflammation. Molecular and Cellular Biology. 35: 1686-99. PMID 25733684 DOI: 10.1128/Mcb.01321-14  0.364
2015 Nie T, Hui X, Gao X, Nie B, Mao L, Tang X, Yuan R, Li K, Li P, Xu A, Liu P, Ding S, Han W, Cooper GJ, Wu D. Conversion of non-adipogenic fibroblasts into adipocytes by a defined hormone mixture. The Biochemical Journal. 467: 487-94. PMID 25730278 DOI: 10.1042/Bj20140727  0.348
2015 Lim CY, Bi X, Wu D, Kim JB, Gunning PW, Hong W, Han W. Tropomodulin3 is a novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through cortical actin remodeling. Nature Communications. 6: 5951. PMID 25575350 DOI: 10.1038/Ncomms6951  0.381
2015 Ma W, Fuentes G, Shi X, Verma C, Radda GK, Han W. FoxO1 negatively regulates leptin-induced POMC transcription through its direct interaction with STAT3. The Biochemical Journal. 466: 291-8. PMID 25510553 DOI: 10.1042/Bj20141109  0.71
2015 Wu B, Wei S, Petersen N, Ali Y, Wang X, Bacaj T, Rorsman P, Hong W, Südhof TC, Han W. Synaptotagmin-7 phosphorylation mediates GLP-1-dependent potentiation of insulin secretion from β-cells Proceedings of the National Academy of Sciences of the United States of America. 112: 9996-10001. DOI: 10.1073/pnas.1513004112  0.764
2014 Yang W, Thein S, Lim CY, Ericksen RE, Sugii S, Xu F, Robinson RC, Kim JB, Han W. Arp2/3 complex regulates adipogenesis by controlling cortical actin remodelling. The Biochemical Journal. 464: 179-92. PMID 25220164 DOI: 10.1042/Bj20140805  0.558
2014 Wee K, Yang W, Sugii S, Han W. Towards a mechanistic understanding of lipodystrophy and seipin functions. Bioscience Reports. 34. PMID 25195639 DOI: 10.1042/Bsr20140114  0.334
2014 Liu T, Li H, Gounko NV, Zhou Z, Xu A, Hong W, Han W. Detection of insulin granule exocytosis by an electrophysiology method with high temporal resolution reveals enlarged insulin granule pool in BIG3-knockout mice. American Journal of Physiology. Endocrinology and Metabolism. 307: E611-8. PMID 25139048 DOI: 10.1152/Ajpendo.00208.2014  0.692
2014 Qiu B, Shi X, Wong ET, Lim J, Bezzi M, Low D, Zhou Q, Akıncılar SC, Lakshmanan M, Swa HL, Tham JM, Gunaratne J, Cheng KK, Hong W, Lam KS, ... ... Han W, et al. NUCKS is a positive transcriptional regulator of insulin signaling. Cell Reports. 7: 1876-86. PMID 24931609 DOI: 10.1016/J.Celrep.2014.05.030  0.752
2014 Smith GC, Zhang ZY, Mulvey T, Petersen N, Lach S, Xiu P, Phillips A, Han W, Wang MW, Shepherd PR. Clozapine directly increases insulin and glucagon secretion from islets: implications for impairment of glucose tolerance. Schizophrenia Research. 157: 128-33. PMID 24906220 DOI: 10.1016/J.Schres.2014.05.003  0.371
2014 Li H, Wei S, Cheng K, Gounko NV, Ericksen RE, Xu A, Hong W, Han W. BIG3 inhibits insulin granule biogenesis and insulin secretion. Embo Reports. 15: 714-22. PMID 24711543 DOI: 10.1002/Embr.201338181  0.637
2014 Wang Y, Ali Y, Lim CY, Hong W, Pang ZP, Han W. Insulin-stimulated leptin secretion requires calcium and PI3K/Akt activation. The Biochemical Journal. 458: 491-8. PMID 24405299 DOI: 10.1042/Bj20131176  0.729
2014 Wei S, Soh SL, Xia J, Ong WY, Pang ZP, Han W. Motor neuropathy-associated mutation impairs Seipin functions in neurotransmission. Journal of Neurochemistry. 129: 328-38. PMID 24345054 DOI: 10.1111/Jnc.12638  0.624
2014 Wang X, Lacza Z, Sun YE, Han W. Leptin resistance and obesity in mice with deletion of methyl-CpG-binding protein 2 (MeCP2) in hypothalamic pro-opiomelanocortin (POMC) neurons. Diabetologia. 57: 236-45. PMID 24078059 DOI: 10.1007/S00125-013-3072-0  0.623
2014 Yang W, Thein S, Wang X, Bi X, Ericksen RE, Xu F, Han W. BSCL2/seipin regulates adipogenesis through actin cytoskeleton remodelling. Human Molecular Genetics. 23: 502-13. PMID 24026679 DOI: 10.1093/Hmg/Ddt444  0.705
2013 Liu Z, Lim CY, Su MY, Soh SL, Shui G, Wenk MR, Grove KL, Radda GK, Han W, Xiao X. Neonatal overnutrition in mice exacerbates high-fat diet-induced metabolic perturbations. The Journal of Endocrinology. 219: 131-43. PMID 23959078 DOI: 10.1530/Joe-13-0111  0.345
2013 Kostromina E, Wang X, Han W. Altered islet morphology but normal islet secretory function in vitro in a mouse model with microvascular alterations in the pancreas. Plos One. 8: e71277. PMID 23923060 DOI: 10.1371/Journal.Pone.0071277  0.637
2013 Kang NY, Lee SC, Park SJ, Ha HH, Yun SW, Kostromina E, Gustavsson N, Ali Y, Chandran Y, Chun HS, Bae M, Ahn JH, Han W, Radda GK, Chang YT. Visualization and isolation of Langerhans islets by a fluorescent probe PiY. Angewandte Chemie (International Ed. in English). 52: 8557-60. PMID 23716493 DOI: 10.1002/Anie.201302149  0.563
2013 Qiu W, Wee K, Takeda K, Lim X, Sugii S, Radda GK, Han W. Suppression of adipogenesis by pathogenic seipin mutant is associated with inflammatory response. Plos One. 8: e57874. PMID 23520483 DOI: 10.1371/Journal.Pone.0057874  0.516
2013 Yang W, Thein S, Guo X, Xu F, Venkatesh B, Sugii S, Radda GK, Han W. Seipin differentially regulates lipogenesis and adipogenesis through a conserved core sequence and an evolutionarily acquired C-terminus. The Biochemical Journal. 452: 37-44. PMID 23458123 DOI: 10.1042/Bj20121870  0.579
2013 Shi X, Wang X, Li Q, Su M, Chew E, Wong ET, Lacza Z, Radda GK, Tergaonkar V, Han W. Nuclear factor κB (NF-κB) suppresses food intake and energy expenditure in mice by directly activating the Pomc promoter. Diabetologia. 56: 925-36. PMID 23370526 DOI: 10.1007/S00125-013-2831-2  0.699
2013 Burchfield JG, Lu J, Fazakerley DJ, Tan SX, Ng Y, Mele K, Buckley MJ, Han W, Hughes WE, James DE. Novel systems for dynamically assessing insulin action in live cells reveals heterogeneity in the insulin response. Traffic (Copenhagen, Denmark). 14: 259-73. PMID 23252720 DOI: 10.1111/Tra.12035  0.581
2013 Wei S, Soh SL, Qiu W, Yang W, Seah CJ, Guo J, Ong WY, Pang ZP, Han W. Seipin regulates excitatory synaptic transmission in cortical neurons. Journal of Neurochemistry. 124: 478-89. PMID 23173741 DOI: 10.1111/Jnc.12099  0.743
2013 Yang W, Guo X, Thein S, Xu F, Sugii S, Baas PW, Radda GK, Han W. Regulation of adipogenesis by cytoskeleton remodelling is facilitated by acetyltransferase MEC-17-dependent acetylation of α-tubulin. The Biochemical Journal. 449: 605-12. PMID 23126280 DOI: 10.1042/Bj20121121  0.55
2013 Lee P, Leong W, Tan T, Lim M, Han W, Radda GK. In vivo hyperpolarized carbon-13 magnetic resonance spectroscopy reveals increased pyruvate carboxylase flux in an insulin-resistant mouse model. Hepatology (Baltimore, Md.). 57: 515-24. PMID 22911492 DOI: 10.1002/Hep.26028  0.336
2012 Le Guezennec X, Brichkina A, Huang YF, Kostromina E, Han W, Bulavin DV. Wip1-dependent regulation of autophagy, obesity, and atherosclerosis. Cell Metabolism. 16: 68-80. PMID 22768840 DOI: 10.1016/J.Cmet.2012.06.003  0.319
2012 Han W. Dual functions of adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 (APPL1) in insulin signaling and insulin secretion Proceedings of the National Academy of Sciences of the United States of America. 109: 8795-8796. PMID 22615370 DOI: 10.1073/Pnas.1206730109  0.383
2012 Pang ZP, Han W. Regulation of synaptic functions in central nervous system by endocrine hormones and the maintenance of energy homoeostasis. Bioscience Reports. 32: 423-32. PMID 22582733 DOI: 10.1042/BSR20120026  0.483
2012 Gustavsson N, Wu B, Han W. Calcium sensing in exocytosis. Advances in Experimental Medicine and Biology. 740: 731-57. PMID 22453967 DOI: 10.1007/978-94-007-2888-2_32  0.482
2012 Smith GC, Ong WK, Rewcastle GW, Kendall JD, Han W, Shepherd PR. Effects of acutely inhibiting PI3K isoforms and mTOR on regulation of glucose metabolism in vivo. The Biochemical Journal. 442: 161-9. PMID 22142257 DOI: 10.1042/Bj20111913  0.341
2011 Lou PH, Gustavsson N, Wang Y, Radda GK, Han W. Increased lipolysis and energy expenditure in a mouse model with severely impaired glucagon secretion. Plos One. 6: e26671. PMID 22046328 DOI: 10.1371/Journal.Pone.0026671  0.684
2011 Xiong W, Liu T, Wang Y, Chen X, Sun L, Guo N, Zheng H, Zheng L, Ruat M, Han W, Zhang CX, Zhou Z. An inhibitory effect of extracellular Ca2+ on Ca2+-dependent exocytosis. Plos One. 6: e24573. PMID 22028769 DOI: 10.1371/Journal.Pone.0024573  0.574
2011 Liu T, Sun L, Xiong Y, Shang S, Guo N, Teng S, Wang Y, Liu B, Wang C, Wang L, Zheng L, Zhang CX, Han W, Zhou Z. Calcium triggers exocytosis from two types of organelles in a single astrocyte. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10593-601. PMID 21775603 DOI: 10.1523/Jneurosci.6401-10.2011  0.592
2011 Gustavsson N, Wang Y, Kang Y, Seah T, Chua S, Radda GK, Han W. Synaptotagmin-7 as a positive regulator of glucose-induced glucagon-like peptide-1 secretion in mice. Diabetologia. 54: 1824-30. PMID 21424898 DOI: 10.1007/S00125-011-2119-3  0.366
2011 Gustavsson N, Seah T, Lao Y, Radda GK, Südhof TC, Han W. Delayed onset of hyperglycaemia in a mouse model with impaired glucagon secretion demonstrates that dysregulated glucagon secretion promotes hyperglycaemia and type 2 diabetes. Diabetologia. 54: 415-22. PMID 20978738 DOI: 10.1007/S00125-010-1950-2  0.408
2011 Jamieson SM, Smith GC, Kolekar S, Lee W, Singh R, Buchanan C, Denny WA, Han W, Kendall JD, Rewcastle GW, Shepherd PR. Abstract B162: Inhibition of the p110α isoform of PI 3-kinase prevents PIK3CA H1047R mutant tumor growth but is associated with impaired glucose metabolism. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-B162  0.351
2011 Xiong W, Liu T, Wang Y, Chen X, Sun L, Guo N, Zheng H, Zheng L, Ruat M, Han W, Zhang C, Zhou Z. Extracellular Ca2+ Directly Inhibits Exocytosis in Neurons Biophysical Journal. 100: 185a-186a. DOI: 10.1016/J.Bpj.2010.12.1232  0.576
2010 Gustavsson N, Wang X, Wang Y, Seah T, Xu J, Radda GK, Südhof TC, Han W. Neuronal calcium sensor synaptotagmin-9 is not involved in the regulation of glucose homeostasis or insulin secretion. Plos One. 5: e15414. PMID 21085706 DOI: 10.1371/Journal.Pone.0015414  0.749
2010 Wei S, Xu Y, Shi H, Wong SH, Han W, Talbot K, Hong W, Ong WY. EHD1 is a synaptic protein that modulates exocytosis through binding to snapin. Molecular and Cellular Neurosciences. 45: 418-29. PMID 20696250 DOI: 10.1016/J.Mcn.2010.07.014  0.502
2010 Lou PH, Yang G, Huang L, Cui Y, Pourbahrami T, Radda GK, Li C, Han W. Reduced body weight and increased energy expenditure in transgenic mice over-expressing soluble leptin receptor. Plos One. 5: e11669. PMID 20652026 DOI: 10.1371/Journal.Pone.0011669  0.611
2010 Yang L, Zhao L, Gan Z, He Z, Xu J, Gao X, Wang X, Han W, Chen L, Xu T, Li W, Liu Y. Deficiency in RNA editing enzyme ADAR2 impairs regulated exocytosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 3720-32. PMID 20501795 DOI: 10.1096/Fj.09-152363  0.598
2010 Kostromina E, Gustavsson N, Wang X, Lim CY, Radda GK, Li C, Han W. Glucose intolerance and impaired insulin secretion in pancreas-specific signal transducer and activator of transcription-3 knockout mice are associated with microvascular alterations in the pancreas. Endocrinology. 151: 2050-9. PMID 20215569 DOI: 10.1210/En.2009-1199  0.644
2009 Gustavsson N, Han W. Calcium-sensing beyond neurotransmitters: functions of synaptotagmins in neuroendocrine and endocrine secretion. Bioscience Reports. 29: 245-59. PMID 19500075 DOI: 10.1042/Bsr20090031  0.306
2009 Gustavsson N, Wei SH, Hoang DN, Lao Y, Zhang Q, Radda GK, Rorsman P, Südhof TC, Han W. Synaptotagmin-7 is a principal Ca2+ sensor for Ca2+ -induced glucagon exocytosis in pancreas. The Journal of Physiology. 587: 1169-78. PMID 19171650 DOI: 10.1113/Jphysiol.2008.168005  0.62
2009 Zhang J, Luo R, Wu H, Wei S, Han W, Li G. Role of type Ialpha phosphatidylinositol-4-phosphate 5-kinase in insulin secretion, glucose metabolism, and membrane potential in INS-1 beta-cells. Endocrinology. 150: 2127-35. PMID 19116346 DOI: 10.1210/en.2008-0516  0.51
2009 Yang G, Lim CY, Li C, Xiao X, Radda GK, Li C, Cao X, Han W. FoxO1 inhibits leptin regulation of pro-opiomelanocortin promoter activity by blocking STAT3 interaction with specificity protein 1. The Journal of Biological Chemistry. 284: 3719-27. PMID 19049975 DOI: 10.1074/Jbc.M804965200  0.352
2009 LU J, GUSTAVSSON N, LI Q, RADDA GK, SÜDHOF TC, HAN W. GENERATION OF TRANSGENIC MICE FOR IN VIVO DETECTION OF INSULIN-CONTAINING GRANULE EXOCYTOSIS AND QUANTIFICATION OF INSULIN SECRETION Journal of Innovative Optical Health Sciences. 2: 397-405. DOI: 10.1142/S1793545809000711  0.64
2008 Gustavsson N, Lao Y, Maximov A, Chuang JC, Kostromina E, Repa JJ, Li C, Radda GK, Südhof TC, Han W. Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 3992-7. PMID 18308938 DOI: 10.1073/Pnas.0711700105  0.757
2008 Xiao XQ, Glavas MM, Kirigiti MA, Fisher S, Evans AE, Enriori PJ, Lim CY, Han W, Cowley MA, Smith MS, Grove KL. Chronic inflammation is associated with increased insulin resistance susceptibility in neonatally overfed mice The Faseb Journal. 22: 115-115. DOI: 10.1096/Fasebj.22.2_Supplement.115  0.316
2006 Schoch S, Mittelstaedt T, Kaeser PS, Padgett D, Feldmann N, Chevaleyre V, Castillo PE, Hammer RE, Han W, Schmitz F, Lin W, Südhof TC. Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release. The Embo Journal. 25: 5852-63. PMID 17124501 DOI: 10.1038/Sj.Emboj.7601425  0.602
2006 Sun J, Bronk P, Liu X, Han W, Südhof TC. Synapsins regulate use-dependent synaptic plasticity in the calyx of Held by a Ca2+/calmodulin-dependent pathway. Proceedings of the National Academy of Sciences of the United States of America. 103: 2880-5. PMID 16481620 DOI: 10.1073/Pnas.0511300103  0.603
2005 Han W, Rhee JS, Maximov A, Lin W, Hammer RE, Rosenmund C, Südhof TC. C-terminal ECFP fusion impairs synaptotagmin 1 function: crowding out synaptotagmin 1. The Journal of Biological Chemistry. 280: 5089-100. PMID 15561725 DOI: 10.1074/Jbc.M408757200  0.739
2005 Shin OH, Han W, Wang Y, Südhof TC. Evolutionarily conserved multiple C2 domain proteins with two transmembrane regions (MCTPs) and unusual Ca2+ binding properties. The Journal of Biological Chemistry. 280: 1641-51. PMID 15528213 DOI: 10.1074/Jbc.M407305200  0.573
2004 Han W, Rhee JS, Maximov A, Lao Y, Mashimo T, Rosenmund C, Südhof TC. N-glycosylation is essential for vesicular targeting of synaptotagmin 1. Neuron. 41: 85-99. PMID 14715137 DOI: 10.1016/S0896-6273(03)00820-1  0.71
2003 Virmani T, Han W, Liu X, Südhof TC, Kavalali ET. Synaptotagmin 7 splice variants differentially regulate synaptic vesicle recycling. The Embo Journal. 22: 5347-57. PMID 14532108 DOI: 10.1093/Emboj/Cdg514  0.597
2003 Ng YK, Lu X, Gulacsi A, Han W, Saxton MJ, Levitan ES. Unexpected mobility variation among individual secretory vesicles produces an apparent refractory neuropeptide pool. Biophysical Journal. 84: 4127-34. PMID 12770915 DOI: 10.1016/S0006-3495(03)75137-6  0.651
2003 Liu X, Han W, Biederer T, Kavalali E, Südhof T. Identification of Endogenous/transfected Synaptic Proteins in Primary Neuronal Culture by a High-yield Immunogold Labeling Microscopy and Microanalysis. 9: 1498-1499. DOI: 10.1017/s1431927603447491  0.531
2003 Liu X, Han W, Biederer T, Kavalali E, Südhof T. Identification of endogenous/transfected synaptic proteins in primary neuronal culture by a high-yield immunogold labeling Microscopy and Microanalysis. 9: 1498-1499. DOI: 10.1017/S1431927603447491  0.723
2002 Han W, Li D, Levitan ES. A new green fluorescent protein construct for localizing and quantifying peptide release. Annals of the New York Academy of Sciences. 971: 627-33. PMID 12438197 DOI: 10.1111/J.1749-6632.2002.Tb04541.X  0.523
2002 Sugita S, Shin OH, Han W, Lao Y, Südhof TC. Synaptotagmins form a hierarchy of exocytotic Ca(2+) sensors with distinct Ca(2+) affinities. The Embo Journal. 21: 270-80. PMID 11823420 DOI: 10.1093/Emboj/21.3.270  0.579
2001 Yin X, Landay MF, Han W, Levitan ES, Watkins SC, Levenson RM, Farkas DL, Prochownik EV. Dynamic in vivo interactions among Myc network members. Oncogene. 20: 4650-64. PMID 11498788 DOI: 10.1038/Sj.Onc.1204606  0.522
2001 Sugita S, Han W, Butz S, Liu X, Fernández-Chacón R, Lao Y, Südhof TC. Synaptotagmin VII as a plasma membrane Ca(2+) sensor in exocytosis. Neuron. 30: 459-73. PMID 11395007 DOI: 10.1016/S0896-6273(01)00290-2  0.315
1999 Burke NA, Takimoto K, Li D, Han W, Watkins SC, Levitan ES. Distinct structural requirements for clustering and immobilization of K+ channels by PSD-95. The Journal of General Physiology. 113: 71-80. PMID 9874689 DOI: 10.1085/Jgp.113.1.71  0.497
1997 Burke NV, Han W, Li D, Takimoto K, Watkins SC, Levitan ES. Neuronal peptide release is limited by secretory granule mobility. Neuron. 19: 1095-102. PMID 9390522 DOI: 10.1016/S0896-6273(00)80400-6  0.539
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