James J. Crowley - Publications

Genetics University of North Carolina, Chapel Hill, Chapel Hill, NC 
Genetics, antipsychotics

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Watson HJ, Yilmaz Z, Thornton LM, Hübel C, Coleman JRI, Gaspar HA, Bryois J, Hinney A, Leppä VM, Mattheisen M, Medland SE, Ripke S, Yao S, Giusti-Rodríguez P, ... ... Crowley JJ, et al. Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa. Nature Genetics. PMID 31308545 DOI: 10.1038/s41588-019-0439-2  0.36
2018 Levinson CA, Zerwas SC, Brosof LC, Thornton LM, Strober M, Pivarunas B, Crowley JJ, Yilmaz Z, Berrettini WH, Brandt H, Crawford S, Fichter MM, Halmi KA, Johnson C, Kaplan AS, et al. Associations between dimensions of anorexia nervosa and obsessive-compulsive disorder: An examination of personality and psychological factors in patients with anorexia nervosa. European Eating Disorders Review : the Journal of the Eating Disorders Association. PMID 30136346 DOI: 10.1002/Erv.2635  0.36
2016 Didion JP, Morgan AP, Yadgary L, Bell TA, McMullan RC, Ortiz de Solorzano L, Britton-Davidian J, Bult CJ, Campbell KJ, Castiglia R, Ching YH, Chunco AJ, Crowley JJ, Chesler EJ, Förster DW, et al. R2d2 drives selfish sweeps in the house mouse. Molecular Biology and Evolution. PMID 26882987 DOI: 10.1093/Molbev/Msw036  1
2015 Teng BL, Nikolova VD, Riddick NV, Agster KL, Crowley JJ, Baker LK, Koller BH, Pedersen CA, Jarstfer MB, Moy SS. Reversal of social deficits by subchronic oxytocin in two autism mouse models. Neuropharmacology. PMID 26748053 DOI: 10.1016/J.Neuropharm.2015.12.025  1
2015 Sun W, Liu Y, Crowley JJ, Chen TH, Zhou H, Chu H, Huang S, Kuan PF, Li Y, Miller DR, Shaw GD, Wu Y, Zhabotynsky V, McMillan L, Zou F, et al. IsoDOT Detects Differential RNA-isoform Expression/Usage with respect to a Categorical or Continuous Covariate with High Sensitivity and Specificity. Journal of the American Statistical Association. 110: 975-986. PMID 26617424 DOI: 10.1080/01621459.2015.1040880  1
2015 Vilhjálmsson BJ, Yang J, Finucane HK, Gusev A, Lindström S, Ripke S, Genovese G, Loh PR, Bhatia G, Do R, Hayeck T, Won HH, Kathiresan S, et al. Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. American Journal of Human Genetics. 97: 576-592. PMID 26430803 DOI: 10.1016/J.Ajhg.2015.09.001  1
2015 Clark SL, McClay JL, Adkins DE, Aberg KA, Kumar G, Nerella S, Xie L, Collins AL, Crowley JJ, Quakenbush CR, Hillard CE, Gao G, Shabalin AA, Peterson RE, Copeland WE, et al. Deep Sequencing of Three Loci Implicated in Large-Scale Genome-Wide Association Study Smoking Meta-Analyses. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. PMID 26283763 DOI: 10.1093/Ntr/Ntv166  1
2015 McClay JL, Vunck SA, Batman AM, Crowley JJ, Vann RE, Beardsley PM, van den Oord EJ. Neurochemical Metabolomics Reveals Disruption to Sphingolipid Metabolism Following Chronic Haloperidol Administration. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 25850894 DOI: 10.1007/S11481-015-9605-1  1
2015 Crowley JJ, Zhabotynsky V, Sun W, Huang S, Pakatci IK, Kim Y, Wang JR, Morgan AP, Calaway JD, Aylor DL, Yun Z, Bell TA, Buus RJ, Calaway ME, Didion JP, et al. Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance. Nature Genetics. 47: 353-60. PMID 25730764 DOI: 10.1038/Ng.3222  1
2015 Didion JP, Morgan AP, Clayshulte AM, Mcmullan RC, Yadgary L, Petkov PM, Bell TA, Gatti DM, Crowley JJ, Hua K, Aylor DL, Bai L, Calaway M, Chesler EJ, French JE, et al. A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2. Plos Genetics. 11: e1004850. PMID 25679959 DOI: 10.1371/Journal.Pgen.1004850  1
2015 Bulik-Sullivan BK, Loh PR, Finucane HK, Ripke S, Yang J, Patterson N, Daly MJ, Price AL, Neale BM. LD Score regression distinguishes confounding from polygenicity in genome-wide association studies. Nature Genetics. 47: 291-5. PMID 25642630 DOI: 10.1038/Ng.3211  1
2015 Crowley JJ, Collins AL, Lee RJ, Nonneman RJ, Farrell MS, Ancalade N, Mugford JW, Agster KL, Nikolova VD, Moy SS, Sullivan PF. Disruption of the microRNA 137 primary transcript results in early embryonic lethality in mice. Biological Psychiatry. 77: e5-7. PMID 25016316 DOI: 10.1016/J.Biopsych.2014.05.022  1
2015 Crowley JJ, Sakamoto K. Psychiatric genomics: Outlook for 2015 and challenges for 2020 Current Opinion in Behavioral Sciences. 2: 102-107. DOI: 10.1016/J.Cobeha.2014.12.005  1
2014 Morgan AP, Crowley JJ, Nonneman RJ, Quackenbush CR, Miller CN, Ryan AK, Bogue MA, Paredes SH, Yourstone S, Carroll IM, Kawula TH, Bower MA, Sartor RB, Sullivan PF. The antipsychotic olanzapine interacts with the gut microbiome to cause weight gain in mouse. Plos One. 9: e115225. PMID 25506936 DOI: 10.1371/Journal.Pone.0115225  1
2014 Gusev A, Lee SH, Trynka G, Finucane H, Vilhjálmsson BJ, Xu H, Zang C, Ripke S, Bulik-Sullivan B, Stahl E, Kähler AK, Hultman CM, Purcell SM, et al. Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases. American Journal of Human Genetics. 95: 535-52. PMID 25439723 DOI: 10.1016/J.Ajhg.2014.10.004  1
2014 . Biological insights from 108 schizophrenia-associated genetic loci. Nature. 511: 421-7. PMID 25056061 DOI: 10.1038/Nature13595  1
2014 Szatkiewicz JP, O'Dushlaine C, Chen G, Chambert K, Moran JL, Neale BM, Fromer M, Ruderfer D, Akterin S, Bergen SE, Kähler A, Magnusson PK, Kim Y, Crowley JJ, Rees E, et al. Copy number variation in schizophrenia in Sweden. Molecular Psychiatry. 19: 762-73. PMID 24776740 DOI: 10.1038/Mp.2014.40  1
2014 Zou F, Sun W, Crowley JJ, Zhabotynsky V, Sullivan PF, Pardo-Manuel de Villena F. A novel statistical approach for jointly analyzing RNA-Seq data from F1 reciprocal crosses and inbred lines. Genetics. 197: 389-99. PMID 24561482 DOI: 10.1534/Genetics.113.160119  1
2014 Crowley JJ, Kim Y, Lenarcic AB, Quackenbush CR, Barrick CJ, Adkins DE, Shaw GS, Miller DR, de Villena FP, Sullivan PF, Valdar W. Genetics of adverse reactions to haloperidol in a mouse diallel: a drug-placebo experiment and Bayesian causal analysis. Genetics. 196: 321-47. PMID 24240528 DOI: 10.1534/Genetics.113.156901  1
2013 Crowley JJ, Ashraf-Khorassani M, Castagnoli N, Sullivan PF. Brain levels of the neurotoxic pyridinium metabolite HPP+ and extrapyramidal symptoms in haloperidol-treated mice. Neurotoxicology. 39: 153-7. PMID 24107597 DOI: 10.1016/J.Neuro.2013.09.005  1
2013 Adkins DE, McClay JL, Vunck SA, Batman AM, Vann RE, Clark SL, Souza RP, Crowley JJ, Sullivan PF, van den Oord EJ, Beardsley PM. Behavioral metabolomics analysis identifies novel neurochemical signatures in methamphetamine sensitization. Genes, Brain, and Behavior. 12: 780-91. PMID 24034544 DOI: 10.1111/Gbb.12081  1
2013 Ripke S, O'Dushlaine C, Chambert K, Moran JL, Kähler AK, Akterin S, Bergen SE, Collins AL, Crowley JJ, Fromer M, Kim Y, Lee SH, Magnusson PK, Sanchez N, Stahl EA, et al. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nature Genetics. 45: 1150-9. PMID 23974872 DOI: 10.1038/Ng.2742  1
2013 Kim Y, Trace SE, Crowley JJ, Brownley KA, Hamer RM, Pisetsky DS, Sullivan PF, Bulik CM. Assessment of gene expression in peripheral blood using RNAseq before and after weight restoration in anorexia nervosa. Psychiatry Research. 210: 287-93. PMID 23778302 DOI: 10.1016/J.Psychres.2013.05.026  1
2013 Crowley JJ, Hilliard CE, Kim Y, Morgan MB, Lewis LR, Muzny DM, Hawes AC, Sabo A, Wheeler DA, Lieberman JA, Sullivan PF, Gibbs RA. Deep resequencing and association analysis of schizophrenia candidate genes. Molecular Psychiatry. 18: 138-40. PMID 22472875 DOI: 10.1038/Mp.2012.28  1
2012 Sun W, Lee S, Zhabotynsky V, Zou F, Wright FA, Crowley JJ, Yun Z, Buus RJ, Miller DR, Wang J, McMillan L, Pardo-Manuel de Villena F, Sullivan PF. Transcriptome atlases of mouse brain reveals differential expression across brain regions and genetic backgrounds. G3 (Bethesda, Md.). 2: 203-11. PMID 22384399 DOI: 10.1534/G3.111.001602  1
2012 Iraqi FA, Mahajne M, Salaymah Y, Sandovski H, Tayem H, Vered K, Balmer L, Hall M, Manship G, Morahan G, Pettit K, Scholten J, Tweedie K, Wallace A, Weerasekera L, ... ... Crowley JJ, et al. The genome architecture of the collaborative cross mouse genetic reference population Genetics. 190: 389-401. PMID 22345608 DOI: 10.1534/Genetics.111.132639  1
2012 Crowley JJ, Kim Y, Szatkiewicz JP, Pratt AL, Quackenbush CR, Adkins DE, van den Oord E, Bogue MA, Yang H, Wang W, Threadgill DW, de Villena FP, McLeod HL, Sullivan PF. Genome-wide association mapping of loci for antipsychotic-induced extrapyramidal symptoms in mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 322-35. PMID 22207321 DOI: 10.1007/S00335-011-9385-8  1
2012 Crowley JJ, Adkins DE, Pratt AL, Quackenbush CR, van den Oord EJ, Moy SS, Wilhelmsen KC, Cooper TB, Bogue MA, McLeod HL, Sullivan PF. Antipsychotic-induced vacuous chewing movements and extrapyramidal side effects are highly heritable in mice. The Pharmacogenomics Journal. 12: 147-55. PMID 21079646 DOI: 10.1038/Tpj.2010.82  1
2010 Konneker TI, Crowley JJ, Quackenbush CR, Keefe RS, Perkins DO, Stroup TS, Lieberman JA, van den Oord E, Sullivan PF. No association of the serotonin transporter polymorphisms 5-HTTLPR and RS25531 with schizophrenia or neurocognition. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 1115-7. PMID 20468059 DOI: 10.1002/Ajmg.B.31077  1
2010 Crowley JJ, Sullivan PF. Genetic investigations in the catie sample Antipsychotic Trials in Schizophrenia: the Catie Project. 237-254. DOI: 10.1017/CBO9780511712265.014  1
2009 Crowley JJ, Sullivan PF, McLeod HL. Pharmacogenomic genome-wide association studies: lessons learned thus far. Pharmacogenomics. 10: 161-3. PMID 19207016 DOI: 10.2217/14622416.10.2.161  1
2008 Crowley JJ, Lipsky RH, Lucki I, Berrettini WH. Variation in the genes encoding vesicular monoamine transporter 2 and beta-1 adrenergic receptor and antidepressant treatment outcome. Psychiatric Genetics. 18: 248-51. PMID 18797399 DOI: 10.1097/Ypg.0B013E3283052Ff7  1
2008 Hoshaw BA, Hill TI, Crowley JJ, Malberg JE, Khawaja X, Rosenzweig-Lipson S, Schechter LE, Lucki I. Antidepressant-like behavioral effects of IGF-I produced by enhanced serotonin transmission. European Journal of Pharmacology. 594: 109-16. PMID 18675266 DOI: 10.1016/J.Ejphar.2008.07.023  1
2008 Crowley JJ, Sullivan PF, McLeod HL. Untapped resources for pharmacogenomic discovery in psychiatry. Current Opinion in Molecular Therapeutics. 10: 205-6. PMID 18535926  1
2008 Alkelai A, Baum A, Carless M, Crowley J, Dasbanerjee T, Dempster E, Docherty S, Hare E, Galsworthy MJ, Grover D, Glubb D, Karlsson R, Mill J, Sen S, Quinones MP, et al. The XVth World Congress of Psychiatric Genetics, October 7-11, 2007: Rapporteur summaries of oral presentations. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 233-77. PMID 18297693 DOI: 10.1002/Ajmg.B.30711  1
2008 Crowley JJ, Keefe RS, Perkins DO, Stroup TS, Lieberman JA, Sullivan PF. The neuregulin 1 promoter polymorphism rs6994992 is not associated with chronic schizophrenia or neurocognition. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 1298-300. PMID 18286587 DOI: 10.1002/Ajmg.B.30727  1
2007 O'Leary OF, Bechtholt AJ, Crowley JJ, Hill TE, Page ME, Lucki I. Depletion of serotonin and catecholamines block the acute behavioral response to different classes of antidepressant drugs in the mouse tail suspension test. Psychopharmacology. 192: 357-71. PMID 17318507 DOI: 10.1007/S00213-007-0728-9  1
2007 O'Leary OF, Bechtholt AJ, Crowley JJ, Valentino RJ, Lucki I. The role of noradrenergic tone in the dorsal raphe nucleus of the mouse in the acute behavioral effects of antidepressant drugs. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 17: 215-26. PMID 16997535 DOI: 10.1016/J.Euroneuro.2006.06.012  1
2006 Crowley JJ, Brodkin ES, Blendy JA, Berrettini WH, Lucki I. Pharmacogenomic evaluation of the antidepressant citalopram in the mouse tail suspension test. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2433-42. PMID 16554742 DOI: 10.1038/Sj.Npp.1301065  1
2005 Ray R, Doyle GA, Crowley JJ, Buono RJ, Oslin DW, Patkar AA, Mannelli P, DeMaria PA, O'Brien CP, Berrettini WH. A functional prodynorphin promoter polymorphism and opioid dependence. Psychiatric Genetics. 15: 295-8. PMID 16314761 DOI: 10.1097/00041444-200512000-00013  1
2005 Crowley JJ, Blendy JA, Lucki I. Strain-dependent antidepressant-like effects of citalopram in the mouse tail suspension test. Psychopharmacology. 183: 257-64. PMID 16220334 DOI: 10.1007/S00213-005-0166-5  1
2005 Crowley JJ, Lucki I. Opportunities to discover genes regulating depression and antidepressant response from rodent behavioral genetics. Current Pharmaceutical Design. 11: 157-69. PMID 15638756 DOI: 10.2174/1381612053382278  1
2005 Smith RJ, Doyle GA, Han AM, Crowley JJ, Oslin DW, Patkar AA, Mannelli P, Demaria PA, O'brien CP, Berrettini WH. Novel exonic mu-opioid receptor gene (OPRM1) polymorphisms not associated with opioid dependence. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 133: 105-9. PMID 15558714 DOI: 10.1002/Ajmg.B.30105  1
2004 Crowley JJ, Jones MD, O'Leary OF, Lucki I. Automated tests for measuring the effects of antidepressants in mice. Pharmacology, Biochemistry, and Behavior. 78: 269-74. PMID 15219767 DOI: 10.1016/J.Pbb.2004.03.014  1
2003 Crowley JJ, Oslin DW, Patkar AA, Gottheil E, DeMaria PA, O'Brien CP, Berrettini WH, Grice DE. A genetic association study of the mu opioid receptor and severe opioid dependence. Psychiatric Genetics. 13: 169-73. PMID 12960749 DOI: 10.1097/00041444-200309000-00006  1
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