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Jonathan P. Schlebach - Publications

Affiliations: 
2007-2012 Medicinal Chemistry and Molecular Pharmacology Purdue University, West Lafayette, IN, United States 
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Chamness LM, Kuntz CP, McKee AG, Penn WD, Hemmerich CM, Rusch DB, Woods H, Meiler J, Schlebach JP. Divergent Pairwise Epistasis in the Context of Unstable Membrane Protein Variants. Biorxiv : the Preprint Server For Biology. PMID 37662415 DOI: 10.1101/2023.08.25.554866  0.421
2022 Kuntz CP, Woods H, McKee AG, Zelt NB, Mendenhall JL, Meiler J, Schlebach JP. Towards generalizable predictions for G protein-coupled receptor variant expression. Biophysical Journal. PMID 35715957 DOI: 10.1016/j.bpj.2022.06.018  0.336
2021 Chamness LM, Zelt NB, Harrington HR, Kuntz CP, Bender BJ, Penn WD, Ziarek JJ, Meiler J, Schlebach JP. Molecular basis for the evolved instability of a human G-protein coupled receptor. Cell Reports. 37: 110046. PMID 34818554 DOI: 10.1016/j.celrep.2021.110046  0.363
2020 Schlebach JP. A protein folding intermediate pulls its weight. The Journal of Biological Chemistry. 295: 11418-11419. PMID 32817126 DOI: 10.1074/Jbc.H120.015166  0.458
2020 Salazar M, Zelt NB, Saldivar R, Kuntz CP, Chen S, Penn WD, Bonneau R, Koehler Leman J, Schlebach JP. Classification of the Molecular Defects Associated with Pathogenic Variants of the SLC6A8 Creatine Transporter. Biochemistry. PMID 32207963 DOI: 10.1021/Acs.Biochem.9B00956  0.308
2020 Penn WD, McKee AG, Kuntz CP, Woods H, Nash V, Gruenhagen TC, Roushar FJ, Chandak M, Hemmerich C, Rusch DB, Meiler J, Schlebach JP. Probing biophysical sequence constraints within the transmembrane domains of rhodopsin by deep mutational scanning. Science Advances. 6: eaay7505. PMID 32181350 DOI: 10.1126/Sciadv.Aay7505  0.387
2020 Harrington HR, Zimmer MH, Chamness LM, Nash V, Penn WD, Miller TF, Mukhopadhyay S, Schlebach JP. Cotranslational folding stimulates programmed ribosomal frameshifting in the alphavirus structural polyprotein. The Journal of Biological Chemistry. PMID 32169904 DOI: 10.1074/Jbc.Ra120.012706  0.402
2019 Marinko JT, Huang H, Penn WD, Capra JA, Schlebach JP, Sanders CR. Folding and Misfolding of Human Membrane Proteins in Health and Disease: From Single Molecules to Cellular Proteostasis. Chemical Reviews. PMID 30608666 DOI: 10.1021/Acs.Chemrev.8B00532  0.468
2018 Roushar FJ, Gruenhagen TC, Penn WD, Li B, Meiler J, Jastrzebska B, Schlebach JP. Contribution of Cotranslational Folding Defects to Membrane Protein Homeostasis. Journal of the American Chemical Society. PMID 30537820 DOI: 10.1021/Jacs.8B08243  0.517
2018 Mallory P, Gutierrez E, Pinkevitch M, Klinginsmith C, Comar WD, Roushar F, Smith AW, Jastrzebska B, Schlebach J. The retinitis pigmentosa-linked mutations in transmembrane helix 5 of rhodopsin disrupt cellular trafficking independently of oligomerization state. Biochemistry. PMID 30085663 DOI: 10.1021/Acs.Biochem.8B00403  0.42
2018 Gruenhagen T, Ziarek JJ, Schlebach JP. Bicelle Size Modulates the Rate of Bacteriorhodopsin Folding. Protein Science : a Publication of the Protein Society. PMID 29604129 DOI: 10.1002/Pro.3414  0.516
2017 Mittendorf KF, Marinko JT, Hampton CM, Ke Z, Hadziselimovic A, Schlebach JP, Law CL, Li J, Wright ER, Sanders CR, Ohi MD. Peripheral myelin protein 22 alters membrane architecture. Science Advances. 3: e1700220. PMID 28695207 DOI: 10.1126/Sciadv.1700220  0.357
2016 Kim JH, Schlebach JP, Lu Z, Peng D, Reasoner KC, Sanders CR. A pH-Mediated Topological Switch within the N-Terminal Domain of Human Caveolin-3. Biophysical Journal. 110: 2475-2485. PMID 27276265 DOI: 10.1016/J.Bpj.2016.05.004  0.418
2016 Schlebach JP, Barrett PJ, Day CA, Kim JH, Kenworthy AK, Sanders CR. Topologically Diverse Human Membrane Proteins Partition to Liquid-Disordered Domains in Phase-Separated Lipid Vesicles. Biochemistry. PMID 26859249 DOI: 10.1021/Acs.Biochem.5B01154  0.47
2015 Schlebach JP, Narayan M, Alford C, Mittendorf KF, Carter BD, Li J, Sanders CR. Conformational Stability and Pathogenic Misfolding of the Integral Membrane Protein PMP22. Journal of the American Chemical Society. PMID 26102530 DOI: 10.1021/Jacs.5B03743  0.535
2015 Schlebach JP, Sanders CR. The safety dance: biophysics of membrane protein folding and misfolding in a cellular context. Quarterly Reviews of Biophysics. 48: 1-34. PMID 25420508 DOI: 10.1017/S0033583514000110  0.526
2015 Schlebach JP, Sanders CR. Influence of Pathogenic Mutations on the Energetics of Translocon-Mediated Bilayer Integration of Transmembrane Helices. The Journal of Membrane Biology. 248: 371-81. PMID 25192979 DOI: 10.1007/S00232-014-9726-0  0.497
2014 Schlebach JP, Woodall NB, Bowie JU, Park C. Bacteriorhodopsin folds through a poorly organized transition state. Journal of the American Chemical Society. 136: 16574-81. PMID 25369295 DOI: 10.1021/Ja508359N  0.568
2014 Kim JH, Peng D, Schlebach JP, Hadziselimovic A, Sanders CR. Modest effects of lipid modifications on the structure of caveolin-3. Biochemistry. 53: 4320-2. PMID 24960539 DOI: 10.1021/Bi5005238  0.394
2014 Schlebach JP, Woodall NB, Bowie JU, Park C. Bacteriorhodopsin folds through a poorly organized transition state Journal of the American Chemical Society. 136: 16574-16581. DOI: 10.1021/ja508359n  0.424
2014 Barrett PJ, Day CA, Song Y, Schlebach JP, Kenworthy AK, Sanders CR. Cholesterol Binding Drives Partitioning of the Amyloid Precursor C99 Protein Into Liquid Ordered Membrane Domains Biophysical Journal. 106: 301a. DOI: 10.1016/J.Bpj.2013.11.1748  0.356
2013 Schlebach JP, Peng D, Kroncke BM, Mittendorf KF, Narayan M, Carter BD, Sanders CR. Reversible folding of human peripheral myelin protein 22, a tetraspan membrane protein. Biochemistry. 52: 3229-41. PMID 23639031 DOI: 10.1021/Bi301635F  0.547
2012 Chang Y, Schlebach JP, VerHeul RA, Park C. Simplified proteomics approach to discover protein-ligand interactions. Protein Science : a Publication of the Protein Society. 21: 1280-7. PMID 22733688 DOI: 10.1002/Pro.2112  0.523
2012 Schlebach JP, Cao Z, Bowie JU, Park C. Revisiting the folding kinetics of bacteriorhodopsin Protein Science. 21: 97-106. PMID 22095725 DOI: 10.1002/Pro.766  0.567
2012 Cao Z, Schlebach JP, Park C, Bowie JU. Thermodynamic stability of bacteriorhodopsin mutants measured relative to the bacterioopsin unfolded state Biochimica Et Biophysica Acta - Biomembranes. 1818: 1049-1054. PMID 21880269 DOI: 10.1016/J.Bbamem.2011.08.019  0.548
2011 Schlebach JP, Kim MS, Joh NH, Bowie JU, Park C. Probing membrane protein unfolding with pulse proteolysis Journal of Molecular Biology. 406: 545-551. PMID 21192947 DOI: 10.1016/J.Jmb.2010.12.018  0.572
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