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Steven D. Cappell, Ph.D. - Publications

Affiliations: 
2010 Pharmacology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pharmacology, Biochemistry
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17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lang F, Cornwell JA, Kaur K, Elmogazy O, Zhang W, Zhang M, Song H, Sun Z, Wu X, Aladjem MI, Aregger M, Cappell SD, Yang C. Abrogation of the G2/M checkpoint as a chemo sensitization approach for alkylating agents. Neuro-Oncology. PMID 38134889 DOI: 10.1093/neuonc/noad252  0.335
2023 Cornwell JA, Crncec A, Afifi MM, Tang K, Amin R, Cappell SD. Loss of CDK4/6 activity in S/G2 phase leads to cell cycle reversal. Nature. PMID 37407814 DOI: 10.1038/s41586-023-06274-3  0.554
2023 Awadia S, Sitto M, Ram S, Ji W, Liu Y, Damani R, Ray D, Lawrence TS, Galban CJ, Cappell SD, Rehemtulla A. The adapter protein FADD provides an alternate pathway for entry into the cell cycle by regulating APC/C-Cdh1 E3 ubiquitin ligase activity. The Journal of Biological Chemistry. 104786. PMID 37146968 DOI: 10.1016/j.jbc.2023.104786  0.533
2021 Nathans JF, Cornwell JA, Afifi MM, Paul D, Cappell SD. Cell cycle inertia underlies a bifurcation in cell fates after DNA damage. Science Advances. 7. PMID 33523889 DOI: 10.1126/sciadv.abe3882  0.412
2020 Yang HW, Cappell SD, Jaimovich A, Liu C, Chung M, Daigh LH, Pack LR, Fan Y, Regot S, Covert M, Meyer T. Stress-mediated exit to quiescence restricted by increasing persistence in CDK4/6 activation. Elife. 9. PMID 32255427 DOI: 10.7554/Elife.44571  0.532
2019 Chung M, Liu C, Yang HW, Köberlin MS, Cappell SD, Meyer T. Transient Hysteresis in CDK4/6 Activity Underlies Passage of the Restriction Point in G1. Molecular Cell. PMID 31543423 DOI: 10.1016/J.Molcel.2019.08.020  0.524
2018 Cappell SD, Mark KG, Garbett D, Pack LR, Rape M, Meyer T. EMI1 switches from being a substrate to an inhibitor of APC/C to start the cell cycle. Nature. PMID 29875408 DOI: 10.1038/S41586-018-0199-7  0.464
2016 Cappell SD, Chung M, Jaimovich A, Spencer SL, Meyer T. Irreversible APC(Cdh1) Inactivation Underlies the Point of No Return for Cell-Cycle Entry. Cell. 166: 167-180. PMID 27368103 DOI: 10.1016/J.Cell.2016.05.077  0.444
2013 Spencer SL, Cappell SD, Tsai FC, Overton KW, Wang CL, Meyer T. The proliferation-quiescence decision is controlled by a bifurcation in CDK2 activity at mitotic exit. Cell. 155: 369-83. PMID 24075009 DOI: 10.1016/J.Cell.2013.08.062  0.497
2012 Lambert NA, Johnston CA, Cappell SD, Kuravi S, Kimple AJ, Willard FS, Siderovski DP. Regulators of G-protein Signaling accelerate GPCR signaling kinetics and govern sensitivity solely by accelerating GTPase activity (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 15, (7066-7071) DOI: 10.1073/pnas.0912934107) Proceedings of the National Academy of Sciences of the United States of America. 109: 2175. DOI: 10.1073/Pnas.1200427109  0.485
2011 Torres MP, Clement ST, Cappell SD, Dohlman HG. Cell cycle-dependent phosphorylation and ubiquitination of a G protein alpha subunit. The Journal of Biological Chemistry. 286: 20208-16. PMID 21521692 DOI: 10.1074/Jbc.M111.239343  0.537
2011 Cappell SD, Dohlman HG. Selective regulation of MAP kinase signaling by an endomembrane phosphatidylinositol 4-kinase. The Journal of Biological Chemistry. 286: 14852-60. PMID 21388955 DOI: 10.1074/Jbc.M110.195073  0.58
2010 Cappell SD, Baker R, Skowyra D, Dohlman HG. Systematic analysis of essential genes reveals important regulators of G protein signaling. Molecular Cell. 38: 746-57. PMID 20542006 DOI: 10.1016/J.Molcel.2010.05.026  0.646
2010 Lambert NA, Johnston CA, Cappell SD, Kuravi S, Kimple AJ, Willard FS, Siderovski DP. Regulators of G-protein signaling accelerate GPCR signaling kinetics and govern sensitivity solely by accelerating GTPase activity. Proceedings of the National Academy of Sciences of the United States of America. 107: 7066-71. PMID 20351284 DOI: 10.1073/Pnas.0912934107  0.579
2008 Brown JW, Prieto LM, Perez-Stable C, Montoya M, Cappell S, Fishman LM. Estrogen and progesterone lower cyclin B1 AND D1 expression, block cell cycle in G2/M, and trigger apoptosis in human adrenal carcinoma cell cultures. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 40: 306-10. PMID 18491248 DOI: 10.1055/S-2008-1073140  0.413
2007 Willard MD, Willard FS, Li X, Cappell SD, Snider WD, Siderovski DP. Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth factor-mediated differentiation. The Embo Journal. 26: 2029-40. PMID 17380122 DOI: 10.1038/Sj.Emboj.7601659  0.478
2004 Brown JW, Cappell S, Perez-Stable C, Fishman LM. Extracts from two marine sponges lower cyclin B1 levels, cause a G2/M cell cycle block and trigger apoptosis in SW-13 human adrenal carcinoma cells. Toxicon : Official Journal of the International Society On Toxinology. 43: 841-6. PMID 15284019 DOI: 10.1016/J.Toxicon.2004.03.017  0.449
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