Sudhakar R. Chintharlapalli, Ph.D. - Publications

Affiliations: 
2006 Texas A & M University, College Station, TX, United States 
Area:
Biochemistry

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Singhal M, Gengenbacher N, La Porta S, Gehrs S, Shi J, Kamiyama M, Bodenmiller DM, Fischl A, Schieb B, Besemfelder E, Chintharlapalli S, Augustin HG. Preclinical validation of a novel metastasis-inhibiting Tie1 function-blocking antibody. Embo Molecular Medicine. e11164. PMID 32302470 DOI: 10.15252/Emmm.201911164  0.374
2020 Li Z, Korhonen EA, Merlini A, Strauss J, Wihuri E, Nurmi H, Antila S, Paech J, Deutsch U, Engelhardt B, Chintharlapalli S, Koh GY, Flügel A, Alitalo K. Angiopoietin-2 blockade ameliorates autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS. The Journal of Clinical Investigation. PMID 32149735 DOI: 10.1172/Jci130308  0.345
2020 Chintharlapalli S, Fischl A, Yu CP, Iversen P. Abstract 1675: Enhanced antitumor effect of dual EGFR and VEGFR2 inhibition in EGFR-mutated non-small cell lung cancer (NSCLC) patient-derived tumor xenograft (PDX) models Cancer Research. 80: 1675-1675. DOI: 10.1158/1538-7445.Am2020-1675  0.353
2019 Fischl AS, Wang X, Falcon BL, Almonte-Baldonado R, Bodenmiller D, Evans G, Stewart J, Wilson T, Hipskind P, Manro JR, Uhlik MT, Chintharlapalli S, Gerald D, Alsop DC, Benjamin LE, et al. Inhibition of Sphingosine Phosphate Receptor 1 Signaling Enhances the Efficacy of VEGF Receptor Inhibition. Molecular Cancer Therapeutics. PMID 30787172 DOI: 10.1158/1535-7163.Mct-18-0548  0.451
2018 Emmerson PJ, Duffin KL, Chintharlapalli S, Wu X. GDF15 and Growth Control. Frontiers in Physiology. 9: 1712. PMID 30542297 DOI: 10.3389/Fphys.2018.01712  0.33
2018 Swearingen M, Falcon B, Chintharlapalli S, Uhlik M. An Endothelial Cell/Mesenchymal Stem Cell Coculture Cord Formation Assay to Model Vascular Biology In Vitro. Methods of Molecular Biology. 1683: 371-382. PMID 29082503 DOI: 10.1007/978-1-4939-7357-6_21  0.357
2017 Lee L, Huber L, Stewart J, Mathews M, Falcon B, Chintharlapalli S. Evaluation of AFP expression as a predictive marker for response to anti-VEGFR-2 inhibition. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 28: iii19-iii20. PMID 32135817 DOI: 10.1093/Annonc/Mdx261.024  0.302
2017 Um SL, Peek VL, Stephens JR, Baker JA, Cannon HK, Cook JD, Wulur IH, Agyei R, Chintharlapalli S, Evans RJ, Feaver WJ, Huber L, Lee LN, Liu L, Ma L, et al. Abstract 519: Antitumor activity of MET antibody emibetuzumab (LY2875358) in combination with EGFR inhibitors in erlotinib resistant (ER) xenograft mouse models Cancer Research. 77: 519-519. DOI: 10.1158/1538-7445.Am2017-519  0.379
2017 Tetreault J, Chintharlapalli S, Leung D, Gerald D, Lee L, Almonte-Baldonado R, Huber L, Xu J, Ramamurthy B, Pereira J, Croy J, Lu J, Liu L. Abstract 3090: LY3207447, a tetravalent bispecific antibody targeting VEGFR2 and angiopoietin-2, provides a more efficient anti-angiogenic therapy and an alternative for combination Cancer Research. 77: 3090-3090. DOI: 10.1158/1538-7445.Am2017-3090  0.409
2017 Bodenmiller DM, Stewart JA, Evans GF, Peek VL, Stephens JR, Lin X, Iyer S, Falcon BL, Chintharlapalli S, Yan SB, Fischl AS. Abstract 1823: Characterization of the anti-angiogenic properties of merestinib (LY2801653), an oncokinase inhibitor Cancer Research. 77: 1823-1823. DOI: 10.1158/1538-7445.Am2017-1823  0.425
2016 Falcon BL, Chintharlapalli S, Uhlik MT, Pytowski B. Antagonist antibodies to vascular endothelial growth factor receptor 2 (VEGFR-2) as anti-angiogenic agents Pharmacology & Therapeutics. 164: 204-225. PMID 27288725 DOI: 10.1016/J.Pharmthera.2016.06.001  0.414
2016 Uhlik MT, Liu J, Falcon BL, Iyer S, Stewart J, Celikkaya H, O'Mahony M, Sevinsky C, Lowes C, Douglass L, Jeffries C, Bodenmiller D, Chintharlapalli S, Fischl A, Gerald D, et al. Stromal-Based Signatures for the Classification of Gastric Cancer. Cancer Research. 76: 2573-2586. PMID 27197264 DOI: 10.1158/0008-5472.Can-16-0022  0.394
2016 Wu W, Stewart J, King C, Jones B, Flack R, Pratt S, Berryman R, Swearingen M, Bodenmiller D, Lin X, Uhlik M, Falcon B, Fischl A, Manro J, Tiu R, ... Chintharlapalli S, et al. Abstract 930: Combined inhibition of pan-RAF and VEGFR-2 mediates antitumor activity in KRAS mutant non-small cell lung cancer (NSCLC) through enhanced inhibition of tumor angiogenesis and growth Cancer Research. 76: 930-930. DOI: 10.1158/1538-7445.Am2016-930  0.501
2016 Chintharlapalli SR, Croy JE, Leung D, Gerald D, Lu J, Iversen PW, Lee LN, Huber L, Tetreault J, Almonte-Baldonado R, Xu J, Ramamurthy B, Pereira JA, Chow C, Hanauske A, et al. Abstract 3259: LY3127804, a novel anti-Angiopoietin-2 antibody in combination with an anti-VEGFR2 antibody potently inhibits angiogenesis, tumor growth and metastasis Cancer Research. 76: 3259-3259. DOI: 10.1158/1538-7445.Am2016-3259  0.39
2015 Shen Y, Zeng L, Novosyadlyy R, Forest A, Zhu A, Korytko A, Zhang H, Eastman SW, Topper M, Hindi S, Covino N, Persaud K, Kang Y, Burtrum D, Surguladze D, ... ... Chintharlapalli S, et al. A bi-functional antibody-receptor domain fusion protein simultaneously targeting IGF-IR and VEGF for degradation. Mabs. 0. PMID 26073904 DOI: 10.1080/19420862.2015.1055442  0.411
2014 Falcon BL, Swearingen M, Gough WH, Lee L, Foreman R, Uhlik M, Hanson JC, Lee JA, McClure DB, Chintharlapalli S. An in vitro cord formation assay identifies unique vascular phenotypes associated with angiogenic growth factors. Plos One. 9: e106901. PMID 25210890 DOI: 10.1371/Journal.Pone.0106901  0.374
2014 Liu J, Falcon BL, Nagy JA, Jaminet SS, Li D, Doman TN, Chintharlapalli S, Pytowski B, Uhlik MT, Dvorak H, Benjamin L, Fischl AS. Abstract 2359: Bioinformatics analysis of an Ad-VEGF flank angiogenesis model identifies vessel subtype gene signatures: Implications for anti-VEGF therapy Cancer Research. 74: 2359-2359. DOI: 10.1158/1538-7445.Am2014-2359  0.38
2013 Falcon BL, O'Clair B, McClure D, Evans GF, Stewart J, Swearingen ML, Chen Y, Allard K, Lee LN, Neote K, McEwen DP, Uhlik MT, Chintharlapalli S. Development and characterization of a high-throughput in vitro cord formation model insensitive to VEGF inhibition. Journal of Hematology & Oncology. 6: 31. PMID 23622716 DOI: 10.1186/1756-8722-6-31  0.353
2013 Gerald D, Chintharlapalli S, Augustin HG, Benjamin LE. Angiopoietin-2: an attractive target for improved antiangiogenic tumor therapy. Cancer Research. 73: 1649-57. PMID 23467610 DOI: 10.1158/0008-5472.Can-12-4697  0.333
2012 Kim K, Chadalapaka G, Pathi SS, Jin UH, Lee JS, Park YY, Cho SG, Chintharlapalli S, Safe S. Induction of the transcriptional repressor ZBTB4 in prostate cancer cells by drug-induced targeting of microRNA-17-92/106b-25 clusters. Molecular Cancer Therapeutics. 11: 1852-62. PMID 22752225 DOI: 10.1158/1535-7163.Mct-12-0181  0.793
2011 Meier T, Uhlik M, Chintharlapalli S, Dowless M, Van Horn R, Stewart J, Blosser W, Cook J, Young D, Ye X, Evans G, Credille K, Ballard D, Huber L, Capen A, et al. Tasisulam sodium, an antitumor agent that inhibits mitotic progression and induces vascular normalization. Molecular Cancer Therapeutics. 10: 2168-78. PMID 21903607 DOI: 10.1158/1535-7163.Mct-11-0323  0.548
2011 Chintharlapalli S, Papineni S, Lei P, Pathi S, Safe S. Betulinic acid inhibits colon cancer cell and tumor growth and induces proteasome-dependent and -independent downregulation of specificity proteins (Sp) transcription factors. Bmc Cancer. 11: 371. PMID 21864401 DOI: 10.1186/1471-2407-11-371  0.828
2011 Chintharlapalli S, Papineni S, Lee SO, Lei P, Jin UH, Sherman SI, Santarpia L, Safe S. Inhibition of pituitary tumor-transforming gene-1 in thyroid cancer cells by drugs that decrease specificity proteins. Molecular Carcinogenesis. 50: 655-67. PMID 21268135 DOI: 10.1002/Mc.20738  0.801
2010 Kim JH, Jung JY, Shim JH, Kim J, Choi KH, Shin JA, Choi ES, Lee SO, Chintharlapalli S, Kwon KH, Leem DH, Cho NP, Cho SD. Apoptotic Effect of Tolfenamic Acid in KB Human Oral Cancer Cells: Possible Involvement of the p38 MAPK Pathway. Journal of Clinical Biochemistry and Nutrition. 47: 74-80. PMID 20664734 DOI: 10.3164/Jcbn.10-02  0.599
2010 Lee SO, Abdelrahim M, Yoon K, Chintharlapalli S, Papineni S, Kim K, Wang H, Safe S. Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth. Cancer Research. 70: 6824-36. PMID 20660371 DOI: 10.1158/0008-5472.Can-10-1992  0.839
2010 Cho SD, Lee SO, Chintharlapalli S, Abdelrahim M, Khan S, Yoon K, Kamat AM, Safe S. Activation of nerve growth factor-induced B alpha by methylene-substituted diindolylmethanes in bladder cancer cells induces apoptosis and inhibits tumor growth. Molecular Pharmacology. 77: 396-404. PMID 20023005 DOI: 10.1124/Mol.109.061143  0.782
2010 Choi KH, Kim HK, Kim JH, Choi ES, Shin JA, Lee SO, Chintharlapalli S, Safe S, Abdelrahim M, Kong G, Choi HS, Jung JY, Cho HT, Cho NP, Cho SD. The p38 MAPK pathway is critical for 5,5'-dibromodiindolylmethane-induced apoptosis to prevent oral squamous carcinoma cells. European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (Ecp). 19: 153-9. PMID 19949342 DOI: 10.1097/Cej.0B013E328333D088  0.643
2010 Guo J, Chintharlapalli S, Lee SO, Cho SD, Lei P, Papineni S, Safe S. Peroxisome proliferator-activated receptor gamma-dependent activity of indole ring-substituted 1,1-bis(3'-indolyl)-1-(p-biphenyl)methanes in cancer cells. Cancer Chemotherapy and Pharmacology. 66: 141-50. PMID 19823826 DOI: 10.1007/S00280-009-1144-0  0.78
2010 Zeng W, Wortinger M, Yang WJ, Peek V, Yan L, Lu J, Chow C, Vaillancourt P, Davies J, Denning I, Weir S, McClure D, Chintharlapalli S, Liu L. Abstract 2583: LA480, a bivalent humanized c-Met monoclonal antibody, inhibits tumor growth without eliciting significant agonist activity Cancer Research. 70: 2583-2583. DOI: 10.1158/1538-7445.Am10-2583  0.514
2009 Lee SO, Chintharlapalli S, Liu S, Papineni S, Cho SD, Yoon K, Safe S. p21 expression is induced by activation of nuclear nerve growth factor-induced Balpha (Nur77) in pancreatic cancer cells. Molecular Cancer Research : McR. 7: 1169-78. PMID 19584258 DOI: 10.1158/1541-7786.Mcr-08-0473  0.819
2009 Chintharlapalli S, Papineni S, Abdelrahim M, Abudayyeh A, Jutooru I, Chadalapaka G, Wu F, Mertens-Talcott S, Vanderlaag K, Cho SD, Smith R, Safe S. Oncogenic microRNA-27a is a target for anticancer agent methyl 2-cyano-3,11-dioxo-18beta-olean-1,12-dien-30-oate in colon cancer cells. International Journal of Cancer. 125: 1965-74. PMID 19582879 DOI: 10.1002/Ijc.24530  0.801
2009 Papineni S, Chintharlapalli S, Abdelrahim M, Lee SO, Burghardt R, Abudayyeh A, Baker C, Herrera L, Safe S. Tolfenamic acid inhibits esophageal cancer through repression of specificity proteins and c-Met. Carcinogenesis. 30: 1193-201. PMID 19406933 DOI: 10.1093/Carcin/Bgp092  0.825
2009 Jutooru I, Chadalapaka G, Chintharlapalli S, Papineni S, Safe S. Induction of apoptosis and nonsteroidal anti-inflammatory drug-activated gene 1 in pancreatic cancer cells by a glycyrrhetinic acid derivative. Molecular Carcinogenesis. 48: 692-702. PMID 19125423 DOI: 10.1002/Mc.20518  0.834
2008 Inamoto T, Papineni S, Chintharlapalli S, Cho SD, Safe S, Kamat AM. 1,1-Bis(3'-indolyl)-1-(p-chlorophenyl)methane activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth. Molecular Cancer Therapeutics. 7: 3825-33. PMID 19074857 DOI: 10.1158/1535-7163.Mct-08-0730  0.819
2008 Cho SD, Chintharlapalli S, Abdelrahim M, Papineni S, Liu S, Guo J, Lei P, Abudayyeh A, Safe S. 5,5'-Dibromo-bis(3'-indolyl)methane induces Kruppel-like factor 4 and p21 in colon cancer cells. Molecular Cancer Therapeutics. 7: 2109-20. PMID 18645021 DOI: 10.1158/1535-7163.Mct-07-2311  0.804
2008 Chadalapaka G, Jutooru I, Chintharlapalli S, Papineni S, Smith R, Li X, Safe S. Curcumin decreases specificity protein expression in bladder cancer cells. Cancer Research. 68: 5345-54. PMID 18593936 DOI: 10.1158/0008-5472.Can-07-6805  0.827
2008 Safe S, Papineni S, Chintharlapalli S. Cancer chemotherapy with indole-3-carbinol, bis(3'-indolyl)methane and synthetic analogs. Cancer Letters. 269: 326-38. PMID 18501502 DOI: 10.1016/J.Canlet.2008.04.021  0.821
2008 Lei P, Abdelrahim M, Cho SD, Liu S, Chintharlapalli S, Safe S. 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through activation of c-jun N-terminal kinase. Carcinogenesis. 29: 1139-47. PMID 18460448 DOI: 10.1093/Carcin/Bgn103  0.668
2008 Hong J, Samudio I, Chintharlapalli S, Safe S. 1,1-bis(3'-indolyl)-1-(p-substituted phenyl)methanes decrease mitochondrial membrane potential and induce apoptosis in endometrial and other cancer cell lines. Molecular Carcinogenesis. 47: 492-507. PMID 18085536 DOI: 10.1002/Mc.20407  0.709
2008 York M, Abdelrahim M, Chintharlapalli S, Lucero SD, Safe S. 1,1-bis(3'-indolyl)-1-(p-substitutedphenyl)methanes induce apoptosis and inhibit renal cell carcinoma growth. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 6743-52. PMID 18006776 DOI: 10.1158/1078-0432.Ccr-07-0967  0.626
2008 Papineni S, Chintharlapalli S, Safe S. Methyl 2-cyano-3,11-dioxo-18 beta-olean-1,12-dien-30-oate is a peroxisome proliferator-activated receptor-gamma agonist that induces receptor-independent apoptosis in LNCaP prostate cancer cells. Molecular Pharmacology. 73: 553-65. PMID 17989348 DOI: 10.1124/Mol.107.041285  0.777
2008 Cho SD, Lei P, Abdelrahim M, Yoon K, Liu S, Guo J, Papineni S, Chintharlapalli S, Safe S. 1,1-bis(3'-indolyl)-1-(p-methoxyphenyl)methane activates Nur77-independent proapoptotic responses in colon cancer cells. Molecular Carcinogenesis. 47: 252-63. PMID 17957723 DOI: 10.1002/Mc.20378  0.808
2008 Inamoto T, Papineni S, Chintharlapalli S, Cho S, Black PC, McConkey DJ, Dinney CP, Safe SH, Kamat AM. A NOVEL ACTIVATOR OF THE ORPHAN NUCLEAR RECEPTOR Nurr1 INHIBITS BLADDER TUMOR GROWTH Journal of Urology. 179: 369-369. DOI: 10.1016/S0022-5347(08)61081-2  0.751
2007 Mertens-Talcott SU, Chintharlapalli S, Li X, Safe S. The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells. Cancer Research. 67: 11001-11. PMID 18006846 DOI: 10.1158/0008-5472.Can-07-2416  0.574
2007 Chintharlapalli S, Papineni S, Liu S, Jutooru I, Chadalapaka G, Cho SD, Murthy RS, You Y, Safe S. 2-cyano-lup-1-en-3-oxo-20-oic acid, a cyano derivative of betulinic acid, activates peroxisome proliferator-activated receptor gamma in colon and pancreatic cancer cells. Carcinogenesis. 28: 2337-46. PMID 17724373 DOI: 10.1093/Carcin/Bgm189  0.829
2007 Reddivari L, Vanamala J, Chintharlapalli S, Safe SH, Miller JC. Anthocyanin fraction from potato extracts is cytotoxic to prostate cancer cells through activation of caspase-dependent and caspase-independent pathways. Carcinogenesis. 28: 2227-35. PMID 17522067 DOI: 10.1093/Carcin/Bgm117  0.615
2007 Chintharlapalli S, Papineni S, Jutooru I, McAlees A, Safe S. Structure-dependent activity of glycyrrhetinic acid derivatives as peroxisome proliferator-activated receptor {gamma} agonists in colon cancer cells. Molecular Cancer Therapeutics. 6: 1588-98. PMID 17513608 DOI: 10.1158/1535-7163.Mct-07-0022  0.823
2007 Chintharlapalli S, Papineni S, Ramaiah SK, Safe S. Betulinic acid inhibits prostate cancer growth through inhibition of specificity protein transcription factors. Cancer Research. 67: 2816-23. PMID 17363604 DOI: 10.1158/0008-5472.Can-06-3735  0.797
2007 Cho SD, Yoon K, Chintharlapalli S, Abdelrahim M, Lei P, Hamilton S, Khan S, Ramaiah SK, Safe S. Nur77 agonists induce proapoptotic genes and responses in colon cancer cells through nuclear receptor-dependent and nuclear receptor-independent pathways. Cancer Research. 67: 674-83. PMID 17234778 DOI: 10.1158/0008-5472.Can-06-2907  0.779
2007 Chintharlapalli S, Papineni S, Safe S. 1,1-bis(3'-indolyl)-1-(p-substitutedphenyl)methanes inhibit growth, induce apoptosis, and decrease the androgen receptor in LNCaP prostate cancer cells through peroxisome proliferator-activated receptor gamma-independent pathways. Molecular Pharmacology. 71: 558-69. PMID 17093136 DOI: 10.1124/Mol.106.028696  0.812
2006 Chintharlapalli S, Papineni S, Safe S. 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through PPARgamma-dependent and PPARgamma-independent pathways. Molecular Cancer Therapeutics. 5: 1362-70. PMID 16731770 DOI: 10.1158/1535-7163.Mct-06-0002  0.828
2006 Kassouf W, Chintharlapalli S, Abdelrahim M, Nelkin G, Safe S, Kamat AM. Inhibition of bladder tumor growth by 1,1-bis(3'-indolyl)-1-(p-substitutedphenyl)methanes: a new class of peroxisome proliferator-activated receptor gamma agonists. Cancer Research. 66: 412-8. PMID 16397256 DOI: 10.1158/0008-5472.Can-05-2755  0.685
2005 Chintharlapalli S, Papineni S, Baek SJ, Liu S, Safe S. 1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl)methanes are peroxisome proliferator-activated receptor gamma agonists but decrease HCT-116 colon cancer cell survival through receptor-independent activation of early growth response-1 and nonsteroidal anti-inflammatory drug-activated gene-1. Molecular Pharmacology. 68: 1782-92. PMID 16155208 DOI: 10.1124/Mol.105.017046  0.834
2005 Chintharlapalli S, Burghardt R, Papineni S, Ramaiah S, Yoon K, Safe S. Activation of Nur77 by selected 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induces apoptosis through nuclear pathways. The Journal of Biological Chemistry. 280: 24903-14. PMID 15871945 DOI: 10.1074/Jbc.M500107200  0.823
2005 Chintharlapalli S, Papineni S, Konopleva M, Andreef M, Samudio I, Safe S. 2-Cyano-3,12-dioxoolean-1,9-dien-28-oic acid and related compounds inhibit growth of colon cancer cells through peroxisome proliferator-activated receptor gamma-dependent and -independent pathways. Molecular Pharmacology. 68: 119-28. PMID 15798084 DOI: 10.1124/Mol.105.011437  0.847
2005 Chintharlapalli SR, Jasti M, Malladi S, Parsa KV, Ballestero RP, González-García M. BMRP is a Bcl-2 binding protein that induces apoptosis. Journal of Cellular Biochemistry. 94: 611-26. PMID 15547950 DOI: 10.1002/Jcb.20292  0.415
2005 Kassouf W, Safe S, Abdelrahim M, Chintharlapalli S, Nelkin GM, Kamat AM. 778: Activity of Novel Agonists of Peroxisome Proliferator-Activated Receptor Gamma (Ppargamma) Against Human Transitional Cell Tumors Journal of Urology. 173: 211-211. DOI: 10.1016/S0022-5347(18)34947-4  0.568
2004 Chintharlapalli S, Smith R, Samudio I, Zhang W, Safe S. 1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl)methanes induce peroxisome proliferator-activated receptor gamma-mediated growth inhibition, transactivation, and differentiation markers in colon cancer cells. Cancer Research. 64: 5994-6001. PMID 15342379 DOI: 10.1158/0008-5472.Can-04-0399  0.77
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