| Year |
Citation |
Score |
| 2023 |
Li T, Song X, Stephen P, Yin H, Lin SX. New insights into the substrate inhibition of Human 17β-hydroxysteroid dehydrogenase type 1. The Journal of Steroid Biochemistry and Molecular Biology. 106246. PMID 36634828 DOI: 10.1016/j.jsbmb.2023.106246 |
0.351 |
|
| 2021 |
Thériault JF, Poirier D, Lin SX. The multi-specific human 17 beta-hydroxysteroid dehydrogenase type 7: Non-competitive inhibitors can target different catalyses to facilitate breast cancer treatment. The Journal of Steroid Biochemistry and Molecular Biology. 105963. PMID 34400276 DOI: 10.1016/j.jsbmb.2021.105963 |
0.332 |
|
| 2019 |
Li T, Stephen P, Zhu DW, Shi R, Lin SX. Crystal structures of human 17β-hydroxysteroid dehydrogenase type 1 complexed with estrone and NADP reveal the mechanism of substrate inhibition. The Febs Journal. PMID 30768851 DOI: 10.1111/Febs.14784 |
0.396 |
|
| 2018 |
Stephen P, Ye S, Zhou M, Song J, Zhang R, Wang ED, Giegé R, Lin SX. Structure of Escherichia coli arginyl-tRNA synthetase in complex with tRNA: pivotal role of the D-loop. Journal of Molecular Biology. PMID 29678554 DOI: 10.1016/J.Jmb.2018.04.011 |
0.34 |
|
| 2018 |
Li T, Zhu D, Labrie F, Lin S. CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 COMPLEXED WITH Dual-Site Inhibitor EM-139 Health. 10: 1079-1089. DOI: 10.2210/Pdb6Dtp/Pdb |
0.39 |
|
| 2017 |
Wang XQ, Aka JA, Li T, Xu D, Doillon CJ, Lin SX. Inhibition of 17beta-hydroxysteroid dehydrogenase type 7 modulates breast cancer protein profile and enhances apoptosis by down-regulating GRP78. The Journal of Steroid Biochemistry and Molecular Biology. PMID 28645527 DOI: 10.1016/J.Jsbmb.2017.06.009 |
0.321 |
|
| 2017 |
Han H, Thériault JF, Chen G, Lin SX. Substrate Inhibition of 17beta-HSD1 in living cells and regulation of 17beta-HSD7 by 17beta-HSD1 knockdown. The Journal of Steroid Biochemistry and Molecular Biology. PMID 28554725 DOI: 10.1016/J.Jsbmb.2017.05.011 |
0.432 |
|
| 2017 |
Xu D, Aka JA, Wang R, Lin SX. 17beta-hydroxysteroid dehydrogenase type 5 is negatively correlated to apoptosis inhibitor GRP78 and tumor-secreted protein PGK1, and modulates breast cancer cell viability and proliferation. The Journal of Steroid Biochemistry and Molecular Biology. PMID 28457968 DOI: 10.1016/J.Jsbmb.2017.04.009 |
0.346 |
|
| 2016 |
Aka JA, Calvo EL, Lin SX. Genomic data on breast cancer transcript profile modulation by 17beta-hydroxysteroid dehydrogenase type 1 and 17-beta-estradiol. Data in Brief. 9: 1000-1012. PMID 27900352 DOI: 10.1016/J.Dib.2016.11.010 |
0.353 |
|
| 2016 |
Aka JA, Calvo EL, Lin SX. Estradiol-independent modulation of breast cancer transcript profile by 17beta-hydroxysteroid dehydrogenase type 1. Molecular and Cellular Endocrinology. PMID 27544780 DOI: 10.1016/J.Mce.2016.08.026 |
0.329 |
|
| 2016 |
He W, Gauri M, Li T, Wang R, Lin SX. Current knowledge of the multifunctional 17β-hydroxysteroid dehydrogenase type 1 (HSD17B1). Gene. PMID 27102893 DOI: 10.1016/j.gene.2016.04.031 |
0.301 |
|
| 2016 |
Zhang B, Hu XJ, Wang XQ, Thériault JF, Zhu DW, Shang P, Labrie F, Lin SX. Human 3α-HSD3: Structural clues of 5α-DHT reverse binding and enzyme down-regulation decreasing MCF7 cell growth. The Biochemical Journal. PMID 26929402 DOI: 10.1042/Bcj20160083 |
0.3 |
|
| 2015 |
Maltais R, Trottier A, Barbeau X, Lagüe P, Perreault M, Thériault JF, Lin SX, Poirier D. Impact of structural modifications at positions 13, 16 and 17 of 16β-(m-carbamoylbenzyl)-estradiol on 17β-hydroxysteroid dehydrogenase type 1 inhibition and estrogenic activity. The Journal of Steroid Biochemistry and Molecular Biology. PMID 26519987 DOI: 10.1016/J.Jsbmb.2015.10.020 |
0.317 |
|
| 2015 |
Stephen P, Lin SX, Giegé R. Interplay between Catalysts and Substrates for Activity of Class Ib Aminoacyl-tRNA Synthetases and Implications for Pharmacology. Current Topics in Medicinal Chemistry. PMID 26286212 DOI: 10.2174/1568026615666150819110018 |
0.314 |
|
| 2015 |
Xu D, Lin SX. Mimicking postmenopausal steroid metabolism in breast cancer cell culture: Differences in response to DHEA or other steroids as hormone sources. The Journal of Steroid Biochemistry and Molecular Biology. PMID 26200948 DOI: 10.1016/J.Jsbmb.2015.07.009 |
0.397 |
|
| 2015 |
Wang X, Gérard C, Thériault JF, Poirier D, Doillon CJ, Lin SX. Synergistic control of sex hormones by 17β-HSD type 7: a novel target for estrogen-dependent breast cancer. Journal of Molecular Cell Biology. 7: 568-79. PMID 25966904 DOI: 10.1093/Jmcb/Mjv028 |
0.321 |
|
| 2015 |
Zhang CY, Wang WQ, Chen J, Lin SX. Reductive 17beta-hydroxysteroid dehydrogenases which synthesize estradiol and inactivate dihydrotestosterone constitute major and concerted players in ER+ breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 150: 24-34. PMID 25257817 DOI: 10.1016/J.Jsbmb.2014.09.017 |
0.326 |
|
| 2014 |
Zhang B, Zhu DW, Hu XJ, Zhou M, Shang P, Lin SX. Human 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3): the V54L mutation restricting the steroid alternative binding and enhancing the 20α-HSD activity. The Journal of Steroid Biochemistry and Molecular Biology. 141: 135-43. PMID 24434280 DOI: 10.1016/J.Jsbmb.2014.01.003 |
0.381 |
|
| 2013 |
Chen J, Wang WQ, Lin SX. Interaction of Androst-5-ene-3β,17β-diol and 5α-androstane-3β,17β-diol with estrogen and androgen receptors: a combined binding and cell study. The Journal of Steroid Biochemistry and Molecular Biology. 137: 316-21. PMID 23416106 DOI: 10.1016/J.Jsbmb.2013.01.012 |
0.308 |
|
| 2013 |
Lin S, Lapointe J. Theoretical and experimental biology in one—A symposium in honour of Professor Kuo-Chen Chou’s 50th anniversary and Professor Richard Giegé’s 40th anniversary of their scientific careers Journal of Biomedical Science and Engineering. 6: 435-442. DOI: 10.4236/Jbise.2013.64054 |
0.33 |
|
| 2012 |
Aka JA, Zerradi M, Houle F, Huot J, Lin SX. 17beta-hydroxysteroid dehydrogenase type 1 modulates breast cancer protein profile and impacts cell migration. Breast Cancer Research : Bcr. 14: R92. PMID 22691413 DOI: 10.1186/Bcr3207 |
0.424 |
|
| 2012 |
Aka JA, Adjo Aka J, Lin SX. Comparison of functional proteomic analyses of human breast cancer cell lines T47D and MCF7. Plos One. 7: e31532. PMID 22384035 DOI: 10.1371/Journal.Pone.0031532 |
0.313 |
|
| 2012 |
Zhang CY, Chen J, Yin DC, Lin SX. The contribution of 17beta-hydroxysteroid dehydrogenase type 1 to the estradiol-estrone ratio in estrogen-sensitive breast cancer cells. Plos One. 7: e29835. PMID 22253796 DOI: 10.1371/Journal.Pone.0029835 |
0.338 |
|
| 2010 |
Lin SX, Chen J, Mazumdar M, Poirier D, Wang C, Azzi A, Zhou M. Molecular therapy of breast cancer: progress and future directions. Nature Reviews. Endocrinology. 6: 485-93. PMID 20644568 DOI: 10.1038/Nrendo.2010.92 |
0.309 |
|
| 2010 |
Aka JA, Mazumdar M, Chen CQ, Poirier D, Lin SX. 17beta-hydroxysteroid dehydrogenase type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production. Molecular Endocrinology (Baltimore, Md.). 24: 832-45. PMID 20172961 DOI: 10.1210/me.2009-0468 |
0.378 |
|
| 2010 |
Ding F, Xu Y, Azzi A, Zhu D, Rehse P, Chen C, Sun S, Lin S. Crystallization of the Membrane-Associated Annexin B1: Roles of Additive Screen, Dynamic Light Scattering, and Bioactivity Assay Crystal Growth & Design. 10: 2528-2532. DOI: 10.1021/Cg901046F |
0.325 |
|
| 2009 |
Mazumdar M, Fournier D, Zhu DW, Cadot C, Poirier D, Lin SX. Binary and ternary crystal structure analyses of a novel inhibitor with 17beta-HSD type 1: a lead compound for breast cancer therapy. The Biochemical Journal. 424: 357-66. PMID 19929851 DOI: 10.1042/Bj20091020 |
0.469 |
|
| 2009 |
Aka JA, Mazumdar M, Lin SX. Reductive 17beta-hydroxysteroid dehydrogenases in the sulfatase pathway: critical in the cell proliferation of breast cancer. Molecular and Cellular Endocrinology. 301: 183-90. PMID 19038308 DOI: 10.1016/J.Mce.2008.10.042 |
0.345 |
|
| 2009 |
Azzi A, Wang T, Zhu DW, Zou YS, Liu WY, Lin SX. Crystal structure of native cinnamomin isoform III and its comparison with other ribosome inactivating proteins. Proteins. 74: 250-5. PMID 18837036 DOI: 10.1002/Prot.22251 |
0.33 |
|
| 2008 |
Lin Y, Zhu D, Wang T, Song J, Zou Y, Zhang Y, Lin S. An Extensive Study of Protein Phase Diagram Modification: Increasing Macromolecular Crystallizability by Temperature Screening Crystal Growth & Design. 8: 4277-4283. DOI: 10.1021/Cg800698P |
0.309 |
|
| 2007 |
Azzi A, Lin SX. Structure function analysis of west nile virus RNA dependent RNA polymerase: molecular model and implications for drug design. Medicinal Chemistry (ShāRiqah (United Arab Emirates)). 3: 455-9. PMID 17897070 DOI: 10.2174/157340607781745438 |
0.307 |
|
| 2007 |
Qiu W, Zhou M, Mazumdar M, Azzi A, Ghanmi D, Luu-The V, Labrie F, Lin SX. Structure-based inhibitor design for an enzyme that binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase. The Journal of Biological Chemistry. 282: 8368-79. PMID 17166832 DOI: 10.1074/Jbc.M606784200 |
0.499 |
|
| 2007 |
Wang T, Zhu D, Zou Y, Azzi A, Shi Y, Jin Y, Zhang R, Lin S. Purification, Refolding, Crystallization and Diffraction Analysis of the Native and Selenomethionine-Substituted Rat Epidymal-Specific Lipocalin † Crystal Growth & Design. 7: 2167-2170. DOI: 10.1021/Cg700945A |
0.339 |
|
| 2007 |
Mazumdar M, Zhou M, Zhu D, Azzi A, Lin S. Crystallogenesis of Steroid-Converting Enzymes and Their Complexes : Enzyme-Ligand Interaction Studies and Inhibitor Design Facilitated by Complex Structures Crystal Growth & Design. 7: 2206-2212. DOI: 10.1021/Cg700709K |
0.441 |
|
| 2006 |
Poirier D, Chang HJ, Azzi A, Boivin RP, Lin SX. Estrone and estradiol C-16 derivatives as inhibitors of type 1 17beta-hydroxysteroid dehydrogenase. Molecular and Cellular Endocrinology. 248: 236-8. PMID 16337735 DOI: 10.1016/J.Mce.2005.10.017 |
0.724 |
|
| 2005 |
Poirier D, Boivin RP, Tremblay MR, Bérubé M, Qiu W, Lin SX. Estradiol-adenosine hybrid compounds designed to inhibit type 1 17beta-hydroxysteroid dehydrogenase. Journal of Medicinal Chemistry. 48: 8134-47. PMID 16366595 DOI: 10.1021/Jm058235E |
0.478 |
|
| 2005 |
Blanchet J, Lin SX, Zhorov BS. Mapping of steroids binding to 17 beta-hydroxysteroid dehydrogenase type 1 using Monte Carlo energy minimization reveals alternative binding modes. Biochemistry. 44: 7218-27. PMID 15882060 DOI: 10.1021/Bi047553X |
0.419 |
|
| 2004 |
Qiu W, Shi R, Lu ML, Zhou M, Roy PH, Lapointe J, Lin SX. Crystal structure of chloramphenicol acetyltransferase B2 encoded by the multiresistance transposon Tn2424. Proteins. 57: 858-61. PMID 15390264 DOI: 10.1002/Prot.20250 |
0.3 |
|
| 2004 |
Qiu W, Zhou M, Labrie F, Lin SX. Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues. Molecular Endocrinology (Baltimore, Md.). 18: 1798-807. PMID 15087468 DOI: 10.1210/Me.2004-0032 |
0.511 |
|
| 2004 |
Shi R, Lin SX. Cofactor hydrogen bonding onto the protein main chain is conserved in the short chain dehydrogenase/reductase family and contributes to nicotinamide orientation. The Journal of Biological Chemistry. 279: 16778-85. PMID 14966133 DOI: 10.1074/Jbc.M313156200 |
0.468 |
|
| 2004 |
Banerjee R, Dubois DY, Gauthier J, Lin SX, Roy S, Lapointe J. The zinc-binding site of a class I aminoacyl-tRNA synthetase is a SWIM domain that modulates amino acid binding via the tRNA acceptor arm. European Journal of Biochemistry / Febs. 271: 724-33. PMID 14764088 DOI: 10.1111/J.1432-1033.2003.03976.X |
0.325 |
|
| 2004 |
Chang HJ, Shi R, Rehse P, Lin SX. Identifying androsterone (ADT) as a cognate substrate for human dehydroepiandrosterone sulfotransferase (DHEA-ST) important for steroid homeostasis: structure of the enzyme-ADT complex. The Journal of Biological Chemistry. 279: 2689-96. PMID 14573603 DOI: 10.1074/jbc.M310446200 |
0.725 |
|
| 2003 |
Nahoum V, Gangloff A, Shi R, Lin SX. How estrogen-specific proteins discriminate estrogens from androgens: a common steroid binding site architecture. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1334-6. PMID 12759331 DOI: 10.1096/Fj.02-0524Fje |
0.704 |
|
| 2003 |
Labrie F, Luu-The V, Labrie C, Bélanger A, Simard J, Lin SX, Pelletier G. Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone. Endocrine Reviews. 24: 152-82. PMID 12700178 DOI: 10.1210/Er.2001-0031 |
0.311 |
|
| 2003 |
Gangloff A, Shi R, Nahoum V, Lin SX. Pseudo-symmetry of C19 steroids, alternative binding orientations, and multispecificity in human estrogenic 17beta-hydroxysteroid dehydrogenase. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 274-6. PMID 12490543 DOI: 10.1096/Fj.02-0397Fje |
0.754 |
|
| 2002 |
Qiu W, Campbell RL, Gangloff A, Dupuis P, Boivin RP, Tremblay MR, Poirier D, Lin SX. A concerted, rational design of type 1 17beta-hydroxysteroid dehydrogenase inhibitors: estradiol-adenosine hybrids with high affinity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1829-31. PMID 12223444 DOI: 10.1096/Fj.02-0026Fje |
0.767 |
|
| 2002 |
Zhou M, Qiu W, Chang HJ, Gangloff A, Lin SX. Purification, crystallization and preliminary X-ray diffraction results of human 17beta-hydroxysteroid dehydrogenase type 5. Acta Crystallographica. Section D, Biological Crystallography. 58: 1048-50. PMID 12037313 DOI: 10.1107/S0907444902005255 |
0.784 |
|
| 2002 |
Rehse PH, Zhou M, Lin SX. Crystal structure of human dehydroepiandrosterone sulphotransferase in complex with substrate. The Biochemical Journal. 364: 165-71. PMID 11988089 DOI: 10.1042/Bj3640165 |
0.448 |
|
| 2002 |
Lu ML, Huang YW, Lin SX. Purification, reconstitution, and steady-state kinetics of the trans-membrane 17 beta-hydroxysteroid dehydrogenase 2. The Journal of Biological Chemistry. 277: 22123-30. PMID 11940569 DOI: 10.1074/Jbc.M111726200 |
0.727 |
|
| 2001 |
Huang YW, Pineau I, Chang HJ, Azzi A, Bellemare V, Laberge S, Lin SX. Critical residues for the specificity of cofactors and substrates in human estrogenic 17beta-hydroxysteroid dehydrogenase 1: variants designed from the three-dimensional structure of the enzyme. Molecular Endocrinology (Baltimore, Md.). 15: 2010-20. PMID 11682630 DOI: 10.1210/Mend.15.11.0730 |
0.788 |
|
| 2001 |
Zhou M, Rehse P, Chang HJ, Luu-The V, Lin SX. Crystallization and preliminary crystallographic results of apo and complex forms of human dehydroepiandrosterone sulfotransferase. Acta Crystallographica. Section D, Biological Crystallography. 57: 1630-3. PMID 11679728 DOI: 10.1107/S0907444901010964 |
0.707 |
|
| 2001 |
Tremblay MR, Lin SX, Poirier D. Chemical synthesis of 16beta-propylaminoacyl derivatives of estradiol and their inhibitory potency on type 1 17beta-hydroxysteroid dehydrogenase and binding affinity on steroid receptors. Steroids. 66: 821-31. PMID 11576622 DOI: 10.1016/S0039-128X(01)00116-7 |
0.496 |
|
| 2001 |
Nahoum V, Gangloff A, Legrand P, Zhu DW, Cantin L, Zhorov BS, Luu-The V, Labrie F, Breton R, Lin SX. Structure of the human 3alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-A resolution. The Journal of Biological Chemistry. 276: 42091-8. PMID 11514561 DOI: 10.1074/Jbc.M105610200 |
0.722 |
|
| 2001 |
Chang HJ, Zhou M, Lin SX. Human dehydroepiandrosterone sulfotransferase: purification and characterization of a recombinant protein. The Journal of Steroid Biochemistry and Molecular Biology. 77: 159-65. PMID 11377982 DOI: 10.1016/S0960-0760(01)00048-6 |
0.723 |
|
| 2001 |
Zhu D, Xu G, Rehse P, Shi R, Zhao F, Lin S. Crystallization and preliminary crystallographic data of fructose-1,6-bisphosphatase from human muscle. Acta Crystallographica Section D-Biological Crystallography. 57: 847-849. PMID 11375504 DOI: 10.1107/S0907444901004371 |
0.347 |
|
| 2001 |
Gangloff A, Garneau A, Huang YW, Yang F, Lin SX. Human oestrogenic 17beta-hydroxysteroid dehydrogenase specificity: enzyme regulation through an NADPH-dependent substrate inhibition towards the highly specific oestrone reduction. The Biochemical Journal. 356: 269-76. PMID 11336660 DOI: 10.1042/0264-6021:3560269 |
0.775 |
|
| 2001 |
Zhou M, Lu ML, Qiu W, Campbell RL, Nahoum V, Lapointe J, Roy PH, Lin SX. Crystallization and preliminary X-ray diffraction analysis of the chloramphenicol acetyltransferase from Tn2424. Acta Crystallographica. Section D, Biological Crystallography. 57: 281-3. PMID 11173480 DOI: 10.1107/S0907444900016802 |
0.353 |
|
| 2001 |
Labrie F, Luu-The V, Lin SX, Simard J, Labrie C. Role of 17 beta-hydroxysteroid dehydrogenases in sex steroid formation in peripheral intracrine tissues. Trends in Endocrinology and Metabolism: Tem. 11: 421-7. PMID 11091120 DOI: 10.1016/S1043-2760(00)00342-8 |
0.445 |
|
| 2000 |
Lin SX, Han Q, Azzi A, Zhu D, Gangloff A, Campbell RL. 3D-structure of human estrogenic 17beta-HSD1: binding with various steroids. The Journal of Steroid Biochemistry and Molecular Biology. 73: 183. PMID 10925218 DOI: 10.1016/S0960-0760(00)00072-8 |
0.715 |
|
| 2000 |
Labrie F, Luu-The V, Lin SX, Simard J, Labrie C, El-Alfy M, Pelletier G, Bélanger A. Intracrinology: role of the family of 17 beta-hydroxysteroid dehydrogenases in human physiology and disease. Journal of Molecular Endocrinology. 25: 1-16. PMID 10915214 DOI: 10.1677/Jme.0.0250001 |
0.431 |
|
| 2000 |
Zhorov BS, Lin S. Monte Carlo‐minimized energy profile of estradiol in the ligand‐binding tunnel of 17β‐hydroxysteroid dehydrogenase: Atomic mechanisms of steroid recognition Proteins. 38: 414-427. PMID 10707028 DOI: 10.1002/(Sici)1097-0134(20000301)38:4<414::Aid-Prot7>3.0.Co;2-X |
0.397 |
|
| 2000 |
Huang YW, Lu ML, Qi H, Lin SX. Membrane-bound human 3beta-hydroxysteroid dehydrogenase: overexpression with His-tag using a baculovirus system and single-step purification. Protein Expression and Purification. 18: 169-74. PMID 10686147 DOI: 10.1006/Prep.1999.1180 |
0.723 |
|
| 2000 |
Han Q, Campbell RL, Gangloff A, Huang YW, Lin SX. Dehydroepiandrosterone and dihydrotestosterone recognition by human estrogenic 17beta-hydroxysteroid dehydrogenase. C-18/c-19 steroid discrimination and enzyme-induced strain. The Journal of Biological Chemistry. 275: 1105-11. PMID 10625652 DOI: 10.1074/Jbc.275.2.1105 |
0.799 |
|
| 2000 |
Zhu DW, Campbell R, Labrie F, Lin SX. Crystallization and preliminary crystal structure of the complex of 17beta-hydroxysteroid dehydrogenase with a dual-site inhibitor. The Journal of Steroid Biochemistry and Molecular Biology. 70: 229-35. PMID 10622412 DOI: 10.1016/S0960-0760(99)00111-9 |
0.526 |
|
| 1999 |
Lin SX, Han Q, Azzi A, Zhu DW, Gangloff A, Campbell RL, Gongloff A. 3D-structure of human estrogenic 17beta-HSD1: binding with various steroids. The Journal of Steroid Biochemistry and Molecular Biology. 69: 425-9. PMID 10419021 DOI: 10.1016/S0960-0760(99)00062-X |
0.768 |
|
| 1999 |
Qiu W, Zhu DW, Azzi A, Campbell RL, Qi H, Poirier D, Lin SX. Two non-reactive ternary complexes of estrogenic 17beta-hydroxysteroid dehydrogenase: crystallization and preliminary structural analysis. The Journal of Steroid Biochemistry and Molecular Biology. 68: 239-44. PMID 10416839 DOI: 10.1016/S0960-0760(99)00036-9 |
0.515 |
|
| 1999 |
Jin J, Lin S. Human estrogenic 17beta-hydroxysteroid dehydrogenase: predominance of estrone reduction and its induction by NADPH. Biochemical and Biophysical Research Communications. 259: 489-493. PMID 10362535 DOI: 10.1006/Bbrc.1999.0704 |
0.383 |
|
| 1999 |
Lin S, Gangloff A, Huang Y, Xie B. Electrophoresis of hydrophobic proteins Analytica Chimica Acta. 383: 101-107. DOI: 10.1016/S0003-2670(98)00491-7 |
0.739 |
|
| 1997 |
Labrie F, Luu-The V, Lin SX, Labrie C, Simard J, Breton R, Bélanger A. The key role of 17 beta-hydroxysteroid dehydrogenases in sex steroid biology. Steroids. 62: 148-58. PMID 9029730 DOI: 10.1016/S0039-128X(96)00174-2 |
0.487 |
|
| 1997 |
Lin SX, Xie B, Li B, Zhou M. Chromatography of hydroxysteroid dehydrogenases. Journal of Chromatography. B, Biomedical Applications. 684: 99-105. PMID 8906468 DOI: 10.1016/0378-4347(96)00180-6 |
0.398 |
|
| 1996 |
Azzi A, Rehse PH, Zhu DW, Campbell RL, Labrie F, Lin SX. Crystal structure of human estrogenic 17 beta-hydroxysteroid dehydrogenase complexed with 17 beta-estradiol. Nature Structural Biology. 3: 665-8. PMID 8756321 DOI: 10.1038/Nsb0896-665 |
0.508 |
|
| 1996 |
Li B, Lin S. Fluorescence‐Energy Transfer in Human Estradiol 17β‐Dehydrogenase‐NADPH Complex and Studies on the Coenzyme Binding Febs Journal. 235: 180-186. PMID 8631327 DOI: 10.1111/J.1432-1033.1996.00180.X |
0.383 |
|
| 1996 |
Zhou M, Breton R, Azzi A, Lin S. Rapid purification of the over-expressed membrane 3 β-hydroxysteroid dehydrogenase in the presence of detergents Journal of Crystal Growth. 168: 142-149. DOI: 10.1016/0022-0248(96)00372-7 |
0.329 |
|
| 1996 |
Han Q, Lin S. A microcrystal selection technique in protein crystallization Journal of Crystal Growth. 168: 181-184. DOI: 10.1016/0022-0248(96)00352-1 |
0.313 |
|
| 1996 |
Zhu D, Azzi A, Rehse P, Lin S. The crystallogenesis of a human estradiol dehydrogenase-substrate complex Journal of Crystal Growth. 168: 275-279. DOI: 10.1016/0022-0248(96)00331-4 |
0.455 |
|
| 1995 |
Zhu DW, Jin JZ, Lin SX. Human 17 beta-hydroxysteroid dehydrogenase: optical properties of its complex with NADP+. The Journal of Steroid Biochemistry and Molecular Biology. 52: 77-81. PMID 7857876 DOI: 10.1016/0960-0760(94)00144-B |
0.463 |
|
| 1995 |
Zhu D, Zhou M, Mao Y, Labrie F, Lin S. Crystallization of human estrogenic 17β-hydroxysteroid dehydrogenase under microgravity Journal of Crystal Growth. 156: 108-111. DOI: 10.1016/0022-0248(95)00252-9 |
0.335 |
|
| 1994 |
Zhu D, Lee X, Labrie F, Lin S. Crystal growth of human estrogenic 17β‐hydroxysteroid dehydrogenase Acta Crystallographica Section D-Biological Crystallography. 50: 550-555. PMID 15299417 DOI: 10.1107/S0907444994001307 |
0.438 |
|
| 1994 |
Breton R, Yang F, Jin JZ, Li B, Labrie F, Lin SX. Human 17 beta-hydroxysteroid dehydrogenase: overproduction using a baculovirus expression system and characterization. The Journal of Steroid Biochemistry and Molecular Biology. 50: 275-82. PMID 7918113 DOI: 10.1016/0960-0760(94)90132-5 |
0.503 |
|
| 1993 |
Jin J, Azzi A, Wang J, Lin S. Preparation of the apoenzyme and holoenzyme forms of human 17β-hydroxysteroid dehydrogenase Journal of Chromatography B: Biomedical Sciences and Applications. 614: 159-163. PMID 8496277 DOI: 10.1016/0378-4347(93)80236-W |
0.309 |
|
| 1992 |
Yang F, Zhu D, Wang J, Lin S. Rapid purification yielding highly active 17β-hydroxysteroid dehydrogenase: application of hydrophobic interaction and affinity fast protein liquid chromatography☆ Journal of Chromatography B: Biomedical Sciences and Applications. 582: 71-76. PMID 1491061 DOI: 10.1016/0378-4347(92)80304-9 |
0.381 |
|
| 1992 |
Lin S, Brisson A, Liu J, Roy PH, Lapointe J. Higher specific activity of the Escherichia coli glutamylt-RNA synthetase purified to homogeneity by a six-hour procedure Protein Expression and Purification. 3: 71-74. PMID 1384858 DOI: 10.1016/1046-5928(92)90058-5 |
0.356 |
|
| 1992 |
Lin SX, Sailofsky B, Lapointe J, Zhou M. Preparative fast purification procedure of various proteins for crystallization Journal of Crystal Growth. 122: 242-245. DOI: 10.1016/0022-0248(92)90252-E |
0.39 |
|
| 1989 |
Lin SX, Vogel WK, Neet KE. Stoichiometry of slow binding of palmitoyl-CoA to liver glucokinase International Journal of Peptide and Protein Research. 34: 333-339. PMID 2599774 DOI: 10.1111/J.1399-3011.1989.Tb01583.X |
0.428 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2000 |
Han Q, Lin S. The Study of Crystallization of Estrogenic 17β-Hydroxysteroid Dehydrogenase with DHEA and DHT at Elevated Temperature Biochemical and Biophysical Research Communications. 277: 100-106. PMID 11027647 DOI: 10.1006/Bbrc.2000.3631 |
0.297 |
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| 2011 |
Zhang CY, Mazumdar M, Zhu DW, Yin DC, Lin SX. Analysis and statistics of crystallisation success increase by composition modification of protein and precipitant mixing ratio. Protein and Peptide Letters. 18: 991-6. PMID 21592082 DOI: 10.2174/0929866511107010991 |
0.291 |
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| 2007 |
Lin SX, McPherson A, Giegé R. Good crystals, still a challenge for structural biology Crystal Growth and Design. 7: 2124-2125. DOI: 10.1021/Cg700745R |
0.287 |
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| 2014 |
Theriault J, Zhu D, Lin S. The trans-membrane 17βHSD7: Kinetic study and preliminary crystallization data Acta Crystallographica Section A. 70. DOI: 10.1107/S2053273314084964 |
0.276 |
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| 2009 |
Bao R, Zhou CZ, Jiang C, Lin SX, Chi CW, Chen Y. The ternary structure of the double-headed arrowhead protease inhibitor API-A complexed with two trypsins reveals a novel reactive site conformation. The Journal of Biological Chemistry. 284: 26676-84. PMID 19640842 DOI: 10.1074/jbc.M109.022095 |
0.275 |
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| 2017 |
Stephen P, Lin SX. RNA-dependent RNA polymerase: Addressing Zika outbreak by a phylogeny-based drug target study. Chemical Biology & Drug Design. PMID 28636772 DOI: 10.1111/Cbdd.13054 |
0.273 |
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| 2018 |
Li T, Maltais R, Poirier D, Lin SX. Combined Biophysical Chemistry Reveals the Finding of a New Covalent Inhibitor with a Low-Reactive Alkyl Halide. The Journal of Physical Chemistry Letters. PMID 30148957 DOI: 10.1021/acs.jpclett.8b02225 |
0.269 |
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| 2012 |
Aka JA, Lin S. Correction: Comparison of Functional Proteomic Analyses of Human Breast Cancer Cell Lines T47D and MCF7. Plos One. 7. DOI: 10.1371/Annotation/18F08A33-35E1-4Bf9-8D21-476757Dccbef |
0.264 |
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| 2016 |
Stephen P, Baz M, Boivin G, Lin SX. Structural Insight into NS5 of Zika Virus Leading to the Discovery of MTase Inhibitors. Journal of the American Chemical Society. 138: 16212-16215. PMID 27998085 DOI: 10.1021/Jacs.6B10399 |
0.248 |
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| 2013 |
Shi R, Chen ZY, Zhu DW, Li C, Shan Y, Xu G, Lin SX. Crystal structures of human muscle fructose-1,6-bisphosphatase: novel quaternary states, enhanced AMP affinity, and allosteric signal transmission pathway. Plos One. 8: e71242. PMID 24086250 DOI: 10.1371/journal.pone.0071242 |
0.245 |
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| 2006 |
Shi R, Azzi A, Gilbert C, Boivin G, Lin SX. Three-dimensional modeling of cytomegalovirus DNA polymerase and preliminary analysis of drug resistance. Proteins. 64: 301-7. PMID 16705640 DOI: 10.1002/Prot.21005 |
0.244 |
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| 2004 |
Azzi A, Lin SX. Human SARS-coronavirus RNA-dependent RNA polymerase: activity determinants and nucleoside analogue inhibitors. Proteins. 57: 12-4. PMID 15326590 DOI: 10.1002/Prot.20194 |
0.237 |
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| 2011 |
Zhang SC, Sun M, Li T, Wang QH, Hao JH, Han Y, Hu XJ, Zhou M, Lin SX. Structure analysis of a new psychrophilic marine protease. Plos One. 6: e26939. PMID 22132082 DOI: 10.1371/journal.pone.0026939 |
0.237 |
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| 2011 |
Gilbert C, Azzi A, Goyette N, Lin SX, Boivin G. Recombinant phenotyping of cytomegalovirus UL54 mutations that emerged during cell passages in the presence of either ganciclovir or foscarnet. Antimicrobial Agents and Chemotherapy. 55: 4019-27. PMID 21709106 DOI: 10.1128/Aac.00334-11 |
0.229 |
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| 2013 |
Lambert AA, Azzi A, Lin SX, Allaire G, St-Gelais KP, Tremblay MJ, Gilbert C. Dendritic cell immunoreceptor is a new target for anti-AIDS drug development: identification of DCIR/HIV-1 inhibitors. Plos One. 8: e67873. PMID 23874461 DOI: 10.1371/Journal.Pone.0067873 |
0.227 |
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| 2019 |
Sang X, Han H, Li T, Lin SX. Mutual regulations and breast cancer cell control by steroidogenic enzymes: dual sex-hormone receptor modulation upon 17β-HSD7 inhibition. The Journal of Steroid Biochemistry and Molecular Biology. 105411. PMID 31207361 DOI: 10.1016/j.jsbmb.2019.105411 |
0.221 |
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| 2019 |
Li T, Zhang W, Hao J, Sun M, Lin SX. Cold-active extracellular lipase: Expression in Sf9 insect cells, purification, and catalysis. Biotechnology Reports (Amsterdam, Netherlands). 21: e00295. PMID 30568889 DOI: 10.1016/j.btre.2018.e00295 |
0.213 |
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| 2018 |
Thériault JF, Lin SX. The dual sex hormone specificity for human reductive 17β-hydroxysteroid dehydrogenase type 7: synergistic function in estrogen and androgen control. The Journal of Steroid Biochemistry and Molecular Biology. PMID 30227243 DOI: 10.1016/j.jsbmb.2018.09.012 |
0.213 |
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| 2012 |
Gilbert C, Azzi A, Lambert AA, Lin S, Allaire G, St-Gelais KP, Tremblay MJ. Three-dimensional modeling of DCIR and identification of new drugs blocking HIV-1 attachment and propagation Retrovirology. 9. DOI: 10.1186/1742-4690-9-S1-P9 |
0.209 |
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| 2010 |
Martin M, Azzi A, Lin SX, Boivin G. Opposite effect of two cytomegalovirus DNA polymerase mutations on replicative capacity and polymerase activity. Antiviral Therapy. 15: 579-86. PMID 20587851 DOI: 10.3851/Imp1565 |
0.206 |
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| 2007 |
Lin SX, Giegé R, Bergfors T. Progress in macromolecular crystallogenesis Crystal Growth and Design. 7: 2123. DOI: 10.1021/Cg700940X |
0.199 |
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| 2019 |
Li T, Zhang W, Lin SX. Steroid enzyme and receptor expression and regulations in breast tumor samples - a statistical evaluation of public data. The Journal of Steroid Biochemistry and Molecular Biology. 105494. PMID 31610224 DOI: 10.1016/j.jsbmb.2019.105494 |
0.196 |
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| 2015 |
Wang X, Sang X, Diorio C, Lin SX, Doillon CJ. In vitro interactions between mammary fibroblasts (Hs 578Bst) and cancer epithelial cells (MCF-7) modulate aromatase, steroid sulfatase and 17β-hydroxysteroid dehydrogenases. Molecular and Cellular Endocrinology. 412: 339-48. PMID 26044867 DOI: 10.1016/j.mce.2015.05.032 |
0.194 |
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| 2021 |
Wang R, Li T, Li G, Lin SX. An unprecedented endocrine target for ovarian cancer: inhibiting 17β-HSD7 supresses cancer cell proliferation and arrests G2/M cycle. American Journal of Cancer Research. 11: 5358-5373. PMID 34873465 |
0.191 |
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| 2019 |
Li F, Zhu Z, Xue M, He W, Zhang T, Feng L, Lin S. siRNA-based breast cancer therapy by suppressing 17β-hydroxysteroid dehydrogenase type 1 in an optimized xenograft cell and molecular biology model in vivo. Drug Design, Development and Therapy. 13: 757-766. PMID 30863015 DOI: 10.2147/DDDT.S180836 |
0.187 |
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| 2019 |
Zhang WF, Li T, Lin SX. Meta-Analysis of steroid-converting enzymes and related receptors in prostate cancer suggesting novel combined therapies. The Journal of Steroid Biochemistry and Molecular Biology. 105559. PMID 31783154 DOI: 10.1016/j.jsbmb.2019.105559 |
0.178 |
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| 2018 |
Sang X, Han H, Poirier D, Lin SX. Steroid sulfatase inhibition success and limitation in breast cancer clinical assays: an underlying mechanism. The Journal of Steroid Biochemistry and Molecular Biology. PMID 29803725 DOI: 10.1016/J.Jsbmb.2018.05.009 |
0.176 |
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| 2023 |
Zhang W, Lin SX. Search of Novel Small Molecule Inhibitors for the Main Protease of SARS-CoV-2. Viruses. 15. PMID 36851795 DOI: 10.3390/v15020580 |
0.17 |
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| 2019 |
Zhang CY, Calvo EL, Yang CQ, Liu J, Sang XY, Lin SX. Transcriptome of 17β-hydroxysteroid dehydrogenase type 2 plays both hormone-dependent and hormone-independent roles in MCF-7 breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 105471. PMID 31513846 DOI: 10.1016/j.jsbmb.2019.105471 |
0.166 |
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| 2023 |
Iqbal S, Lin SX. Deep Drug Discovery of Mac Domain of SARS-CoV-2 (WT) Spike Inhibitors: Using Experimental ACE2 Inhibition TR-FRET Assay, Screening, Molecular Dynamic Simulations and Free Energy Calculations. Bioengineering (Basel, Switzerland). 10. PMID 37627846 DOI: 10.3390/bioengineering10080961 |
0.158 |
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| 2004 |
Xu Q, Xie Z, Ding J, Lin SX, Xu G. Monoclonal antibodies assisting refolding of firefly luciferase. Protein Science : a Publication of the Protein Society. 13: 1851-8. PMID 15215528 DOI: 10.1110/ps.04699904 |
0.15 |
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| 2020 |
Zhang W, Stephen P, Thériault JF, Wang R, Lin SX. Novel Coronavirus Polymerase and Nucleotidyl-transferase Structures: Potential to Target New Outbreaks. The Journal of Physical Chemistry Letters. PMID 32392072 DOI: 10.1021/acs.jpclett.0c00571 |
0.131 |
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| 2021 |
Wang R, Stephen P, Tao Y, Zhang W, Lin SX. Human endeavor for anti-SARS-CoV-2 pharmacotherapy: A major strategy to fight the pandemic. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 137: 111232. PMID 33486202 DOI: 10.1016/j.biopha.2021.111232 |
0.122 |
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| 2019 |
Ran Q, Xiang Y, Stephen P, Wu C, Li T, Lin SX, Li Z. CRIF1-CDK2 Interface Inhibitors: An Unprecedented Strategy for Modulation of Cell Radiosensitivity. Journal of the American Chemical Society. PMID 30653304 DOI: 10.1021/jacs.8b10207 |
0.121 |
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| 2022 |
Sang X, Belmessabih N, Wang R, Stephen P, Lin SX. CRIF1-CDK2 Interface Inhibitors Enhance Taxol Inhibition of the Lethal Triple-Negative Breast Cancer. Cancers. 14. PMID 35205737 DOI: 10.3390/cancers14040989 |
0.114 |
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| 2019 |
Liu WJ, Zhao G, Zhang CY, Yang CQ, Zeng XB, Li J, Zhu K, Zhao SQ, Lu HM, Yin DC, Lin SX. Comparison of the roles of estrogens and androgens in breast cancer and prostate cancer. Journal of Cellular Biochemistry. PMID 31693255 DOI: 10.1002/jcb.29515 |
0.112 |
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| 2020 |
Audet-Walsh É, Lin SX, Wang XQ. Using Omics to better understand steroid biosynthesis, metabolism, and functions. The Journal of Steroid Biochemistry and Molecular Biology. 105686. PMID 32437965 DOI: 10.1016/j.jsbmb.2020.105686 |
0.088 |
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| 2020 |
Wei YC, Lin SX, Tsai PJ, Chen YC. Memory-based optical polarization conversion in a double-[Formula: see text] atomic system with degenerate Zeeman states. Scientific Reports. 10: 13990. PMID 32814785 DOI: 10.1038/s41598-020-70810-8 |
0.028 |
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| 2019 |
Tchernof A, Lin SX, Luu-The V, Simard J. The Passing of Dr. Fernand Labrie (1937-2019): The legacy of excellence in science. The Journal of Steroid Biochemistry and Molecular Biology. PMID 30779933 DOI: 10.1016/J.Jsbmb.2019.02.005 |
0.018 |
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| 2018 |
Hsiao YF, Tsai PJ, Chen HS, Lin SX, Hung CC, Lee CH, Chen YH, Chen YF, Yu IA, Chen YC. Highly Efficient Coherent Optical Memory Based on Electromagnetically Induced Transparency. Physical Review Letters. 120: 183602. PMID 29775362 DOI: 10.1103/Physrevlett.120.183602 |
0.01 |
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| Hide low-probability matches. |
