Linda Sorkin - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
pain, anesthesiology

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Lerman I, Davis B, Huang M, Huang C, Sorkin L, Proudfoot J, Zhong E, Kimball D, Rao R, Simon B, Spadoni A, Strigo I, Baker DG, Simmons AN. Noninvasive vagus nerve stimulation alters neural response and physiological autonomic tone to noxious thermal challenge. Plos One. 14: e0201212. PMID 30759089 DOI: 10.1371/Journal.Pone.0201212  0.352
2018 Sorkin LS, Eddinger KA, Woller SA, Yaksh TL. Origins of antidromic activity in sensory afferent fibers and neurogenic inflammation. Seminars in Immunopathology. PMID 29423889 DOI: 10.1007/s00281-017-0669-2  0.424
2017 Wigerblad G, Huie JR, Yin HZ, Leinders M, Pritchard RA, Koehrn FJ, Xiao WH, Bennett GJ, Huganir RL, Ferguson AR, Weiss JH, Svensson CI, Sorkin LS. Inflammation-induced GluA1 trafficking and membrane insertion of Ca(2+) permeable AMPA receptors in dorsal horn neurons is dependent on spinal tumor necrosis factor, PI3 kinase and protein kinase A. Experimental Neurology. PMID 28412220 DOI: 10.1016/J.Expneurol.2017.04.004  0.317
2016 Sikandar S, Gustavsson Y, Marino MJ, Dickenson AH, Yaksh TL, Sorkin LS, Ramachandran R. Effects of intraplantar Botulinum toxin-B on carrageenan-induced changes in nociception and spinal phosphorylation of GluA1 and Akt. The European Journal of Neuroscience. PMID 27108664 DOI: 10.1111/Ejn.13261  0.458
2015 Yaksh TL, Woller SA, Ramachandran R, Sorkin LS. The search for novel analgesics: targets and mechanisms. F1000prime Reports. 7: 56. PMID 26097729 DOI: 10.12703/P7-56  0.356
2014 Leinders M, Koehrn FJ, Bartok B, Boyle DL, Shubayev V, Kalcheva I, Yu NK, Park J, Kaang BK, Hefferan MP, Firestein GS, Sorkin LS. Differential distribution of PI3K isoforms in spinal cord and dorsal root ganglia: potential roles in acute inflammatory pain. Pain. 155: 1150-60. PMID 24631588 DOI: 10.1016/j.pain.2014.03.003  0.403
2012 Choi JI, Koehrn FJ, Sorkin LS. Carrageenan induced phosphorylation of Akt is dependent on neurokinin-1 expressing neurons in the superficial dorsal horn. Molecular Pain. 8: 4. PMID 22243518 DOI: 10.1186/1744-8069-8-4  0.329
2010 Choi JI, Svensson CI, Koehrn FJ, Bhuskute A, Sorkin LS. Peripheral inflammation induces tumor necrosis factor dependent AMPA receptor trafficking and Akt phosphorylation in spinal cord in addition to pain behavior. Pain. 149: 243-53. PMID 20202754 DOI: 10.1016/J.Pain.2010.02.008  0.326
2010 Schäfers M, Sorkin L. Corrigendum to “Effect of cytokines on neuronal excitability” [Neurosci. Lett. 437 (2008) 188–193] Neuroscience Letters. 481: 191. DOI: 10.1016/j.neulet.2010.07.001  0.313
2009 Sorkin LS, Yaksh TL. Behavioral models of pain states evoked by physical injury to the peripheral nerve. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 6: 609-19. PMID 19789066 DOI: 10.1016/j.nurt.2009.07.007  0.456
2009 Sorkin LS, Boyle DL, Hammaker D, Herman DS, Vail E, Firestein GS. MKK3, an upstream activator of p38, contributes to formalin phase 2 and late allodynia in mice. Neuroscience. 162: 462-71. PMID 19427893 DOI: 10.1016/j.neuroscience.2009.05.008  0.559
2009 Sorkin L, Svensson CI, Jones-Cordero TL, Hefferan MP, Campana WM. Spinal p38 mitogen-activated protein kinase mediates allodynia induced by first-degree burn in the rat. Journal of Neuroscience Research. 87: 948-55. PMID 18855936 DOI: 10.1002/Jnr.21905  0.382
2008 Nagakura Y, Jones TL, Malkmus SA, Sorkin L, Yaksh TL. The sensitization of a broad spectrum of sensory nerve fibers in a rat model of acute postoperative pain and its response to intrathecal pharmacotherapy. Pain. 139: 569-77. PMID 18692315 DOI: 10.1016/j.pain.2008.06.014  0.453
2008 Schäfers M, Sorkin L. Effect of cytokines on neuronal excitability. Neuroscience Letters. 437: 188-93. PMID 18420346 DOI: 10.1016/j.neulet.2008.03.052  0.348
2007 Jones TL, Lustig AC, Sorkin LS. Secondary hyperalgesia in the postoperative pain model is dependent on spinal calcium/calmodulin-dependent protein kinase II alpha activation. Anesthesia and Analgesia. 105: 1650-6, table of con. PMID 18042863 DOI: 10.1213/01.ane.0000287644.00420.49  0.319
2006 Svensson CI, Schäfers M, Jones TL, Yaksh TL, Sorkin LS. Covariance among age, spinal p38 MAP kinase activation and allodynia. The Journal of Pain : Official Journal of the American Pain Society. 7: 337-45. PMID 16632323 DOI: 10.1016/J.Jpain.2005.12.007  0.435
2005 Lee DH, Chang L, Sorkin LS, Chaplan SR. Hyperpolarization-activated, cation-nonselective, cyclic nucleotide-modulated channel blockade alleviates mechanical allodynia and suppresses ectopic discharge in spinal nerve ligated rats. The Journal of Pain : Official Journal of the American Pain Society. 6: 417-24. PMID 15993819 DOI: 10.1016/j.jpain.2005.02.002  0.308
2005 Svensson CI, Schäfers M, Jones TL, Powell H, Sorkin LS. Spinal blockade of TNF blocks spinal nerve ligation-induced increases in spinal P-p38. Neuroscience Letters. 379: 209-13. PMID 15843065 DOI: 10.1016/J.Neulet.2004.12.064  0.311
2005 Yaksh TL, Sorkin LS. Mechanisms of neuropathic pain Current Medicinal Chemistry - Central Nervous System Agents. 5: 129-140. DOI: 10.2174/1568015054022380  0.376
2004 Schäfers M, Marziniak M, Sorkin LS, Yaksh TL, Sommer C. Cyclooxygenase inhibition in nerve-injury- and TNF-induced hyperalgesia in the rat. Experimental Neurology. 185: 160-8. PMID 14697327 DOI: 10.1016/j.expneurol.2003.09.015  0.426
2004 Svensson C, Schaefers M, Jones T, Powell H, Yaksh T, Sorkin L. Spinal nociceptive mechanisms The Journal of Pain. 5: S33. DOI: 10.1016/J.Jpain.2004.02.099  0.519
2003 Schäfers M, Lee DH, Brors D, Yaksh TL, Sorkin LS. Increased sensitivity of injured and adjacent uninjured rat primary sensory neurons to exogenous tumor necrosis factor-alpha after spinal nerve ligation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3028-38. PMID 12684490  0.467
2001 Sorkin LS, Yaksh TL, Doom CM. Pain models display differential sensitivity to Ca2+-permeable non-NMDA glutamate receptor antagonists. Anesthesiology. 95: 965-73. PMID 11605940  0.45
2001 Luo ZD, Chaplan SR, Higuera ES, Sorkin LS, Stauderman KA, Williams ME, Yaksh TL. Upregulation of dorsal root ganglion (alpha)2(delta) calcium channel subunit and its correlation with allodynia in spinal nerve-injured rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1868-75. PMID 11245671  0.404
2001 Luo ZD, Chaplan SR, Higuera ES, Sorkin LS, Stauderman KA, Williams ME, Yaksh TL. Upregulation of Dorsal Root Ganglion α2δ Calcium Channel Subunit and Its Correlation with Allodynia in Spinal Nerve-Injured Rats The Journal of Neuroscience. 21: 1868-1875. DOI: 10.1523/JNEUROSCI.21-06-01868.2001  0.405
1999 Sorkin LS, Yaksh TL, Doom CM. Mechanical allodynia in rats is blocked by a Ca2+ permeable AMPA receptor antagonist. Neuroreport. 10: 3523-6. PMID 10619637  0.369
1999 Sorkin LS, Wallace MS. Acute pain mechanisms. The Surgical Clinics of North America. 79: 213-29. PMID 10352652 DOI: 10.1016/S0039-6109(05)70380-7  0.334
1998 Sorkin LS, Puig S, Jones DL. Spinal bicuculline produces hypersensitivity of dorsal horn neurons: effects of excitatory amino acid antagonists. Pain. 77: 181-90. PMID 9766836 DOI: 10.1016/S0304-3959(98)00094-3  0.353
1997 Wallace MS, Lee J, Sorkin L, Dunn JS, Yaksh T, Yu A. Intravenous lidocaine: effects on controlling pain after anti-GD2 antibody therapy in children with neuroblastoma--a report of a series. Anesthesia and Analgesia. 85: 794-6. PMID 9322457 DOI: 10.1097/00000539-199710000-00014  0.403
1997 Slart R, Yu AL, Yaksh TL, Sorkin LS. An animal model of pain produced by systemic administration of an immunotherapeutic anti-ganglioside antibody. Pain. 69: 119-25. PMID 9060021 DOI: 10.1016/S0304-3959(96)03247-2  0.377
1997 Chaplan SR, Sorkin LS, Willis WD, Merskey H, Carr DB, Casey KL. Agonizing over pain terminology Pain Forum. 6: 81-100.  0.509
1996 Sorkin LS, Puig S. Neuronal model of tactile allodynia produced by spinal strychnine: effects of excitatory amino acid receptor antagonists and a mu-opiate receptor agonist. Pain. 68: 283-92. PMID 9121816 DOI: 10.1016/S0304-3959(96)03130-2  0.322
1994 Marsala M, Sorkin LS, Yaksh TL. Transient spinal ischemia in rat: characterization of spinal cord blood flow, extracellular amino acid release, and concurrent histopathological damage. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 14: 604-14. PMID 8014207 DOI: 10.1038/jcbfm.1994.75  0.481
1993 Sorkin LS, McAdoo DJ, Willis WD. Raphe magnus stimulation-induced antinociception in the cat is associated with release of amino acids as well as serotonin in the lumbar dorsal horn. Brain Research. 618: 95-108. PMID 8402183 DOI: 10.1016/0006-8993(93)90433-N  0.513
1993 Sorkin LS, McAdoo DJ. Amino acids and serotonin are released into the lumbar spinal cord of the anesthetized cat following intradermal capsaicin injections. Brain Research. 607: 89-98. PMID 7683245 DOI: 10.1016/0006-8993(93)91492-B  0.311
1992 Sorkin LS, Westlund KN, Sluka KA, Dougherty PM, Willis WD. Neural changes in acute arthritis in monkeys. IV. Time-course of amino acid release into the lumbar dorsal horn. Brain Research. Brain Research Reviews. 17: 39-50. PMID 1638274 DOI: 10.1016/0165-0173(92)90005-7  0.583
1992 Dougherty PM, Sluka KA, Sorkin LS, Westlund KN, Willis WD. Neural changes in acute arthritis in monkeys. I. Parallel enhancement of responses of spinothalamic tract neurons to mechanical stimulation and excitatory amino acids. Brain Research. Brain Research Reviews. 17: 1-13. PMID 1638273 DOI: 10.1016/0165-0173(92)90002-4  0.645
1992 Sorkin LS, McAdoo DJ, Willis WD. Stimulation in the ventral posterior lateral nucleus of the primate thalamus leads to release of serotonin in the lumbar spinal cord. Brain Research. 581: 307-10. PMID 1393535 DOI: 10.1016/0006-8993(92)90722-L  0.538
1992 Sluka KA, Dougherty PM, Sorkin LS, Willis WD, Westlund KN. Neural changes in acute arthritis in monkeys. III. Changes in substance P, calcitonin gene-related peptide and glutamate in the dorsal horn of the spinal cord. Brain Research. Brain Research Reviews. 17: 29-38. PMID 1379098 DOI: 10.1016/0165-0173(92)90004-6  0.614
1992 Dougherty PM, Palecek J, Paleckova V, Sorkin LS, Willis WD. The role of NMDA and non-NMDA excitatory amino acid receptors in the excitation of primate spinothalamic tract neurons by mechanical, chemical, thermal, and electrical stimuli. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 3025-41. PMID 1353793 DOI: 10.1523/Jneurosci.12-08-03025.1992  0.489
1992 Westlund KN, Sun YC, Sluka KA, Dougherty PM, Sorkin LS, Willis WD. Neural changes in acute arthritis in monkeys. II. Increased glutamate immunoreactivity in the medial articular nerve. Brain Research. Brain Research Reviews. 17: 15-27. PMID 1353392 DOI: 10.1016/0165-0173(92)90003-5  0.574
1991 Simone DA, Sorkin LS, Oh U, Chung JM, Owens C, LaMotte RH, Willis WD. Neurogenic hyperalgesia: central neural correlates in responses of spinothalamic tract neurons. Journal of Neurophysiology. 66: 228-46. PMID 1919669 DOI: 10.1152/Jn.1991.66.1.228  0.622
1991 Westlund KN, Zhang D, Carlton SM, Sorkin LS, Willis WD. Noradrenergic innervation of somatosensory thalamus and spinal cord. Progress in Brain Research. 88: 77-88. PMID 1813936 DOI: 10.1016/S0079-6123(08)63800-5  0.572
1991 Sorkin LS, Hughes MG, Liu D, Willis WD, McAdoo DJ. Release and metabolism of 5-hydroxytryptamine in the cat spinal cord examined with microdialysis. The Journal of Pharmacology and Experimental Therapeutics. 257: 192-9. PMID 1708424  0.423
1991 Klein CM, Sorkin LS, Chung K, Coggeshall RE. Unmyelinated primary afferent fiber stimulation depletes dynorphin A (1-8) immunoreactivity in rat ventral horn. Brain Research. 566: 70-6. PMID 1687665 DOI: 10.1016/0006-8993(91)91682-Q  0.334
1990 Villanueva L, Cliffer KD, Sorkin LS, Le Bars D, Willis WD. Convergence of heterotopic nociceptive information onto neurons of caudal medullary reticular formation in monkey (Macaca fascicularis). Journal of Neurophysiology. 63: 1118-27. PMID 2358866 DOI: 10.1152/Jn.1990.63.5.1118  0.516
1990 Zhang DX, Carlton SM, Sorkin LS, Willis WD. Collaterals of primate spinothalamic tract neurons to the periaqueductal gray. The Journal of Comparative Neurology. 296: 277-90. PMID 2358537 DOI: 10.1002/cne.902960208  0.502
1990 Westlund KN, Sorkin LS, Ferrington DG, Carlton SM, Willcockson HH, Willis WD. Serotoninergic and noradrenergic projections to the ventral posterolateral nucleus of the monkey thalamus. The Journal of Comparative Neurology. 295: 197-207. PMID 2358512 DOI: 10.1002/cne.902950204  0.445
1990 Carlton SM, Westlund KN, Zhang DX, Sorkin LS, Willis WD. Calcitonin gene-related peptide containing primary afferent fibers synapse on primate spinothalamic tract cells. Neuroscience Letters. 109: 76-81. PMID 2314643 DOI: 10.1016/0304-3940(90)90540-P  0.495
1990 Sorkin LS, McAdoo DJ, Willis WD. Release of serotonin following brainstem stimulation: Correlation with inhibition of nociceptive dorsal horn neurons Serotonin and Pain: Proceedings of the International Symposium On Serotonin and Pain. Ics879. 105-115.  0.5
1988 Downie JW, Ferrington DG, Sorkin LS, Willis WD. The primate spinocervicothalamic pathway: responses of cells of the lateral cervical nucleus and spinocervical tract to innocuous and noxious stimuli. Journal of Neurophysiology. 59: 861-85. PMID 3367201 DOI: 10.1152/Jn.1988.59.3.861  0.543
1988 Sorkin LS, Morrow TJ, Casey KL. Physiological identification of afferent fibers and postsynaptic sensory neurons in the spinal cord of the intact, awake cat. Experimental Neurology. 99: 412-27. PMID 3338532 DOI: 10.1016/0014-4886(88)90158-6  0.701
1988 Sorkin LS, Steinman JL, Hughes MG, Willis WD, McAdoo DJ. Microdialysis recovery of serotonin released in spinal cord dorsal horn. Journal of Neuroscience Methods. 23: 131-8. PMID 2451773 DOI: 10.1016/0165-0270(88)90185-9  0.511
1987 Ferrington DG, Sorkin LS, Willis WD. Responses of spinothalamic tract cells in the superficial dorsal horn of the primate lumbar spinal cord. The Journal of Physiology. 388: 681-703. PMID 3656204 DOI: 10.1113/Jphysiol.1987.Sp016638  0.438
1987 Yezierski RP, Sorkin LS, Willis WD. Response properties of spinal neurons projecting to midbrain or midbrain-thalamus in the monkey. Brain Research. 437: 165-70. PMID 2827865 DOI: 10.1016/0006-8993(87)91539-3  0.533
1987 Yezierski RP, Sorkin LS, Willis WD. Response and receptive field properties of primate spinomes-encephalic tract (SMT) cells Pain. 30: S238. DOI: 10.1016/0304-3959(87)91536-3  0.415
1987 Sorkin LS, Hughes MG, Willis WD, McAdoo DJ. Midbrain stimulation induced serotonin (5ht) release in discrete regions of primate spinal CORD recovered with dialysis Pain. 30: S29. DOI: 10.1016/0304-3959(87)91137-7  0.481
1986 Ferrington DG, Sorkin LS, Willis WD. Responses of spinothalamic tract cells in the cat cervical spinal cord to innocuous and graded noxious stimuli. Somatosensory Research. 3: 339-58. PMID 3775154 DOI: 10.3109/07367228609144592  0.55
1986 Sorkin LS, Ferrington DG, Willis WD. Somatotopic organization and response characteristics of dorsal horn neurons in the cervical spinal cord of the cat. Somatosensory Research. 3: 323-38. PMID 3775153 DOI: 10.3109/07367228609144591  0.545
1986 Chung JM, Lee KH, Surmeier DJ, Sorkin LS, Kim J, Willis WD. Response characteristics of neurons in the ventral posterior lateral nucleus of the monkey thalamus. Journal of Neurophysiology. 56: 370-90. PMID 3760926 DOI: 10.1152/Jn.1986.56.2.370  0.688
1986 Chung JM, Surmeier DJ, Lee KH, Sorkin LS, Honda CN, Tsong Y, Willis WD. Classification of primate spinothalamic and somatosensory thalamic neurons based on cluster analysis. Journal of Neurophysiology. 56: 308-27. PMID 3760923 DOI: 10.1152/Jn.1986.56.2.308  0.709
1981 Sorkin LS, Morrow TJ, Casey KL. Spinal cord unit activity: Behaviorally related excitability changes in the awake cat Pain. 11: S128. DOI: 10.1016/0304-3959(81)90360-2  0.657
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