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Wade D. Van Horn, Ph.D. - Publications

Affiliations: 
2007 University of Utah, Salt Lake City, UT 
Area:
General Biophysics
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8/42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Shekhar M, Terashi G, Gupta C, Sarkar D, Debussche G, Sisco NJ, Nguyen J, Mondal A, Vant J, Fromme P, Van Horn WD, Tajkhorshid E, Kihara D, Dill K, Perez A, et al. CryoFold: determining protein structures and data-guided ensembles from cryo-EM density maps. Matter. 4: 3195-3216. PMID 35874311 DOI: 10.1016/j.matt.2021.09.004  0.32
2010 Van Horn WD, Beel AJ, Kang C, Sanders CR. The impact of window functions on NMR-based paramagnetic relaxation enhancement measurements in membrane proteins. Biochimica Et Biophysica Acta. 1798: 140-9. PMID 19751702 DOI: 10.1016/J.Bbamem.2009.08.022  0.35
2009 Kim HJ, Howell SC, Van Horn WD, Jeon YH, Sanders CR. Recent Advances in the Application of Solution NMR Spectroscopy to Multi-Span Integral Membrane Proteins. Progress in Nuclear Magnetic Resonance Spectroscopy. 55: 335-360. PMID 20161395 DOI: 10.1016/J.Pnmrs.2009.07.002  0.353
2009 Van Horn WD, Ogilvie ME, Flynn PF. Reverse micelle encapsulation as a model for intracellular crowding. Journal of the American Chemical Society. 131: 8030-9. PMID 19469539 DOI: 10.1021/Ja901871N  0.722
2008 Van Horn WD, Ogilvie ME, Flynn PF. Use of reverse micelles in membrane protein structural biology. Journal of Biomolecular Nmr. 40: 203-11. PMID 18297402 DOI: 10.1007/S10858-008-9227-5  0.664
2007 Flynn PF, Simorellis AK, Van Horn WD. NMR Studies of Encapsulated Macromolecules Annual Reports On Nmr Spectroscopy. 62: 179-219. DOI: 10.1016/S0066-4103(07)62004-3  0.629
2006 Simorellis AK, Van Horn WD, Flynn PF. Dynamics of low temperature induced water shedding from AOT reverse micelles. Journal of the American Chemical Society. 128: 5082-90. PMID 16608342 DOI: 10.1021/Ja0568401  0.624
2005 Van Horn WD, Simorellis AK, Flynn PF. Low-temperature studies of encapsulated proteins. Journal of the American Chemical Society. 127: 13553-60. PMID 16190719 DOI: 10.1021/Ja052805I  0.642
Low-probability matches (unlikely to be authored by this person)
2013 Barrett PJ, Chen J, Cho MK, Kim JH, Lu Z, Mathew S, Peng D, Song Y, Van Horn WD, Zhuang T, Sönnichsen FD, Sanders CR. The quiet renaissance of protein nuclear magnetic resonance. Biochemistry. 52: 1303-20. PMID 23368985 DOI: 10.1021/Bi4000436  0.296
2015 Zook J, Mo G, Sisco NJ, Craciunescu FM, Hansen DT, Baravati B, Cherry BR, Sykes K, Wachter R, Van Horn WD, Fromme P. NMR Structure of Francisella tularensis Virulence Determinant Reveals Structural Homology to Bet v1 Allergen Proteins. Structure (London, England : 1993). 23: 1116-22. PMID 26004443 DOI: 10.1016/J.Str.2015.03.025  0.286
2021 Hutchison JM, Capone R, Luu DD, Shah KH, Hadziselimovic A, Van Horn WD, Sanders CR. Recombinant SARS-CoV-2 envelope protein traffics to the trans-Golgi network following amphipol-mediated delivery into human cells. The Journal of Biological Chemistry. 100940. PMID 34237302 DOI: 10.1016/j.jbc.2021.100940  0.269
2021 Hutchison JM, Capone R, Luu DD, Hadziselimovic A, Van Horn WD, Sanders CR. Delivery of recombinant SARS-CoV-2 envelope protein into human cells. Biorxiv : the Preprint Server For Biology. PMID 33619482 DOI: 10.1101/2021.02.18.431684  0.266
2012 Van Horn WD, Sanders CR. Prokaryotic diacylglycerol kinase and undecaprenol kinase. Annual Review of Biophysics. 41: 81-101. PMID 22224599 DOI: 10.1146/Annurev-Biophys-050511-102330  0.214
2010 Kang C, Vanoye CG, Welch RC, Van Horn WD, Sanders CR. Functional delivery of a membrane protein into oocyte membranes using bicelles. Biochemistry. 49: 653-5. PMID 20044833 DOI: 10.1021/Bi902155T  0.21
2012 Lu Z, Van Horn WD, Chen J, Mathew S, Zent R, Sanders CR. Bicelles at low concentrations. Molecular Pharmaceutics. 9: 752-61. PMID 22221179 DOI: 10.1021/Mp2004687  0.209
2024 Saccuzzo EG, Mebrat MD, Scelsi HF, Kim M, Ma MT, Su X, Hill SE, Rheaume E, Li R, Torres MP, Gumbart JC, Van Horn WD, Lieberman RL. Competition between inside-out unfolding and pathogenic aggregation in an amyloid-forming β-propeller. Nature Communications. 15: 155. PMID 38168102 DOI: 10.1038/s41467-023-44479-2  0.203
2009 Van Horn WD, Kim HJ, Ellis CD, Hadziselimovic A, Sulistijo ES, Karra MD, Tian C, Sönnichsen FD, Sanders CR. Solution nuclear magnetic resonance structure of membrane-integral diacylglycerol kinase. Science (New York, N.Y.). 324: 1726-9. PMID 19556511 DOI: 10.1126/Science.1171716  0.202
2020 Kim M, Sisco NJ, Hilton JK, Montano CM, Castro MA, Cherry BR, Levitus M, Van Horn WD. Evidence that the TRPV1 S1-S4 membrane domain contributes to thermosensing. Nature Communications. 11: 4169. PMID 32820172 DOI: 10.1038/S41467-020-18026-2  0.195
2019 Sisco NJ, Helsell CVM, Van Horn WD. Competitive Interactions between PIRT, the Cold Sensing Ion Channel TRPM8, and PIP Suggest a Mechanism for Regulation. Scientific Reports. 9: 14128. PMID 31575973 DOI: 10.1038/s41598-019-49912-5  0.19
2016 Liao JY, Anosova I, Bala S, Van Horn WD, Chaput JC. A Parallel Stranded G-Quadruplex Composed of Threose Nucleic Acid (TNA). Biopolymers. PMID 27718227 DOI: 10.1002/Bip.22999  0.189
2014 Peng D, Kim JH, Kroncke BM, Law CL, Xia Y, Droege KD, Van Horn WD, Vanoye CG, Sanders CR. Purification and structural study of the voltage-sensor domain of the human KCNQ1 potassium ion channel. Biochemistry. 53: 2032-42. PMID 24606221 DOI: 10.1021/Bi500102W  0.18
2012 Barrett PJ, Song Y, Van Horn WD, Hustedt EJ, Schafer JM, Hadziselimovic A, Beel AJ, Sanders CR. The amyloid precursor protein has a flexible transmembrane domain and binds cholesterol. Science (New York, N.Y.). 336: 1168-71. PMID 22654059 DOI: 10.1126/Science.1219988  0.169
2013 Van Horn WD. Structural and functional insights into human vitamin K epoxide reductase and vitamin K epoxide reductase-like1. Critical Reviews in Biochemistry and Molecular Biology. 48: 357-72. PMID 23631591 DOI: 10.3109/10409238.2013.791659  0.168
2015 Hilton JK, Rath P, Helsell CV, Beckstein O, Van Horn WD. Understanding thermosensitive transient receptor potential channels as versatile polymodal cellular sensors. Biochemistry. 54: 2401-13. PMID 25812016 DOI: 10.1021/acs.biochem.5b00071  0.161
2016 Kroncke BM, Van Horn WD, Smith J, Kang C, Welch RC, Song Y, Nannemann DP, Taylor KC, Sisco NJ, George AL, Meiler J, Vanoye CG, Sanders CR. Structural basis for KCNE3 modulation of potassium recycling in epithelia. Science Advances. 2: e1501228. PMID 27626070 DOI: 10.1126/Sciadv.1501228  0.147
2015 Anosova I, Kowal EA, Dunn MR, Chaput JC, Van Horn WD, Egli M. The structural diversity of artificial genetic polymers. Nucleic Acids Research. PMID 26673703 DOI: 10.1093/Nar/Gkv1472  0.143
2011 Van Horn WD, Vanoye CG, Sanders CR. Working model for the structural basis for KCNE1 modulation of the KCNQ1 potassium channel. Current Opinion in Structural Biology. 21: 283-91. PMID 21296569 DOI: 10.1016/J.Sbi.2011.01.001  0.14
2018 Hilton JK, Salehpour T, Sisco NJ, Rath P, Van Horn WD. Phosphoinositide-interacting regulator of TRP (PIRT) has opposing effects on human and mouse TRPM8 ion channels. The Journal of Biological Chemistry. PMID 29724821 DOI: 10.1074/jbc.RA118.003563  0.139
2020 Sisco NJ, Luu DD, Kim M, Van Horn WD. PIRT the TRP Channel Regulating Protein Binds Calmodulin and Cholesterol-Like Ligands. Biomolecules. 10. PMID 32245175 DOI: 10.3390/biom10030478  0.134
2016 Rath P, Hilton JK, Sisco NJ, Van Horn WD. Implications of Human Transient Receptor Potential Melastatin 8 (TRPM8) Channel Gating from Menthol Binding Studies of the Sensing Domain. Biochemistry. 55: 114-24. PMID 26653082 DOI: 10.1021/acs.biochem.5b00931  0.126
2016 Anosova I, Kowal EA, Sisco NJ, Sau S, Liao JY, Bala S, Rozners E, Egli M, Chaput JC, Van Horn WD. Structural Insights into Conformational Differences between DNA/TNA and RNA/TNA Chimeric Duplexes. Chembiochem : a European Journal of Chemical Biology. PMID 27347671 DOI: 10.1002/Cbic.201600349  0.122
2019 Hilton JK, Kim M, Van Horn WD. Structural and Evolutionary Insights Point to Allosteric Regulation of TRP Ion Channels. Accounts of Chemical Research. PMID 31149807 DOI: 10.1021/acs.accounts.9b00075  0.113
2020 Garami A, Shimansky YP, Rumbus Z, Vizin RCL, Farkas N, Hegyi J, Szakacs Z, Solymar M, Csenkey A, Chiche DA, Kapil R, Kyle DJ, Van Horn WD, Hegyi P, Romanovsky AA. Hyperthermia induced by transient receptor potential vanilloid-1 (TRPV1) antagonists in human clinical trials: Insights from mathematical modeling and meta-analysis. Pharmacology & Therapeutics. 107474. PMID 31926897 DOI: 10.1016/j.pharmthera.2020.107474  0.113
2021 Luu DD, Owens AM, Mebrat MD, Van Horn WD. A molecular perspective on identifying TRPV1 thermosensitive regions and disentangling polymodal activation. Temperature (Austin, Tex.). 10: 67-101. PMID 37187836 DOI: 10.1080/23328940.2021.1983354  0.109
2012 Shi M, Pedchenko V, Greer BH, Van Horn WD, Santoro SA, Sanders CR, Hudson BG, Eichman BF, Zent R, Pozzi A. Enhancing integrin α1 inserted (I) domain affinity to ligand potentiates integrin α1β1-mediated down-regulation of collagen synthesis. The Journal of Biological Chemistry. 287: 35139-52. PMID 22888006 DOI: 10.1074/Jbc.M112.358648  0.107
2021 Modi T, Risso VA, Martinez-Rodriguez S, Gavira JA, Mebrat MD, Van Horn WD, Sanchez-Ruiz JM, Banu Ozkan S. Hinge-shift mechanism as a protein design principle for the evolution of β-lactamases from substrate promiscuity to specificity. Nature Communications. 12: 1852. PMID 33767175 DOI: 10.1038/s41467-021-22089-0  0.105
2019 Journigan VB, Feng Z, Rahman S, Wang Y, Amin ARMR, Heffner CE, Bachtel N, Wang S, Gonzalez-Rodriguez S, Fernández-Carvajal A, Fernández-Ballester G, Hilton JK, Van Horn WD, Ferrer-Montiel A, Xie XQ, et al. Structure-based design of novel biphenyl amide antagonists of human Transient Receptor Potential Cation Channel Subfamily M Member 8 channels (TRPM8) with potential implications in the treatment of sensory neuropathies. Acs Chemical Neuroscience. PMID 31850745 DOI: 10.1021/Acschemneuro.9B00404  0.099
2023 Orndorff PB, Poddar S, Owens AM, Kumari N, Ugaz BT, Amin S, Van Horn WD, van der Vaart A, Levitus M. Uracil-DNA glycosylase efficiency is modulated by substrate rigidity. Scientific Reports. 13: 3915. PMID 36890276 DOI: 10.1038/s41598-023-30620-0  0.083
2021 Journigan VB, Alarcón-Alarcón D, Feng Z, Wang Y, Liang T, Dawley DC, Amin ARMR, Montano C, Van Horn WD, Xie XQ, Ferrer-Montiel A, Fernández-Carvajal A. Structural and in Vitro Functional Characterization of a Menthyl TRPM8 Antagonist Indicates Species-Dependent Regulation. Acs Medicinal Chemistry Letters. 12: 758-767. PMID 34055223 DOI: 10.1021/acsmedchemlett.1c00001  0.048
2022 Veldhuizen J, Mann HF, Karamanova N, Van Horn WD, Migrino RQ, Brafman D, Nikkhah M. Modeling long QT syndrome type 2 on-a-chip via in-depth assessment of isogenic gene-edited 3D cardiac tissues. Science Advances. 8: eabq6720. PMID 36525500 DOI: 10.1126/sciadv.abq6720  0.042
2014 Van Horn WD. VKORC1 ER mislocalization causes rare disease. Blood. 124: 1215-6. PMID 25147380 DOI: 10.1182/blood-2014-07-586032  0.019
2017 Hilton JK, Van Horn WD. New pieces to an old puzzle: identifying the warfarin-binding site that prevents clotting. Nature Structural & Molecular Biology. 24: 5-6. PMID 28054569 DOI: 10.1038/nsmb.3356  0.015
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