| Year |
Citation |
Score |
| 2023 |
Lu Y, Saibro-Girardi C, Fitz NF, McGuire MR, Ostach MA, Mamun-Or-Rashid ANM, Lefterov I, Koldamova R. Multi-transcriptomics reveals brain cellular responses to peripheral infection in Alzheimer's disease model mice. Cell Reports. 42: 112785. PMID 37436901 DOI: 10.1016/j.celrep.2023.112785 |
0.394 |
|
| 2023 |
Lefterov I, Fitz NF, Lu Y, Koldamova R. and risk of Alzheimer's disease - time to move forward. Frontiers in Neuroscience. 17: 1195724. PMID 37274212 DOI: 10.3389/fnins.2023.1195724 |
0.329 |
|
| 2021 |
Fitz NF, Nam KN, Wolfe CM, Letronne F, Playso BE, Iordanova BE, Kozai TDY, Biedrzycki RJ, Kagan VE, Tyurina YY, Han X, Lefterov I, Koldamova R. Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer's disease. Nature Communications. 12: 3416. PMID 34099706 DOI: 10.1038/s41467-021-23762-0 |
0.455 |
|
| 2020 |
Fitz NF, Wolfe CM, Playso BE, Biedrzycki RJ, Lu Y, Nam KN, Lefterov I, Koldamova R. Trem2 deficiency differentially affects phenotype and transcriptome of human APOE3 and APOE4 mice. Molecular Neurodegeneration. 15: 41. PMID 32703241 DOI: 10.1186/S13024-020-00394-4 |
0.452 |
|
| 2019 |
Lefterov I, Wolfe CM, Fitz NF, Nam KN, Letronne F, Biedrzycki RJ, Kofler J, Han X, Wang J, Schug J, Koldamova R. APOE2 orchestrated differences in transcriptomic and lipidomic profiles of postmortem AD brain. Alzheimer's Research & Therapy. 11: 113. PMID 31888770 DOI: 10.1186/S13195-019-0558-0 |
0.449 |
|
| 2019 |
Fitz NF, Nam KN, Koldamova R, Lefterov I. Therapeutic Targeting of Nuclear Receptors, LXR and RXR, for Alzheimer's Disease. British Journal of Pharmacology. PMID 30924124 DOI: 10.1111/Bph.14668 |
0.464 |
|
| 2019 |
Fitz NF, Playso BE, Wolfe CM, Nam KN, Lefterov I, Koldamova R. P2-208: Lack Of Trem2 Affects The Phenotype And Transcriptome In Mice Expressing Human Apoe3 And Apoe4 Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2615 |
0.399 |
|
| 2019 |
Nam KN, Fitz NF, Biedrzycki RJ, Playso BE, Wolfe CM, Lefterov I, Koldamova R. P2-100: SINGLE-CELL TRANSCRIPTOMIC PROFILING OF TREM2 DEFICIENT MICROGLIA IN RESPONSE TO INTRACRANIAL INFUSION OF Aβ PARTICLES Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2507 |
0.315 |
|
| 2018 |
Wolfe CM, Fitz NF, Nam KN, Lefterov I, Koldamova R. The Role of APOE and TREM2 in Alzheimer's Disease-Current Understanding and Perspectives. International Journal of Molecular Sciences. 20. PMID 30587772 DOI: 10.3390/Ijms20010081 |
0.502 |
|
| 2018 |
Castranio EL, Wolfe CM, Nam KN, Letronne F, Fitz NF, Lefterov I, Koldamova R. ABCA1 haplodeficiency affects the brain transcriptome following traumatic brain injury in mice expressing human APOE isoforms. Acta Neuropathologica Communications. 6: 69. PMID 30049279 DOI: 10.1186/S40478-018-0569-2 |
0.44 |
|
| 2018 |
Lefterov I, Fitz NF, Wolfe CM, Nam KN, Letronne F, Kofler J, Han X, Schug J, Koldamova R. P4-253: Multi-Omics Profiling Identifies Apoe-Allele-Associated Lipid And Gene Expression Patterns In Alzheimer'S Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.07.075 |
0.38 |
|
| 2017 |
Nam KN, Wolfe CM, Fitz NF, Letronne F, Castranio EL, Mounier A, Schug J, Lefterov I, Koldamova R. Integrated approach reveals diet, APOE genotype and sex affect immune response in APP mice. Biochimica Et Biophysica Acta. PMID 29038051 DOI: 10.1016/J.Bbadis.2017.10.018 |
0.492 |
|
| 2017 |
Nam KN, Mounier A, Wolfe CM, Fitz NF, Carter AY, Castranio EL, Kamboh HI, Reeves VL, Wang J, Han X, Schug J, Lefterov I, Koldamova R. Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer's model mice. Scientific Reports. 7: 4307. PMID 28655926 DOI: 10.1038/S41598-017-04412-2 |
0.489 |
|
| 2017 |
Castranio EL, Mounier A, Wolfe CM, Nam KN, Fitz NF, Letronne F, Schug J, Koldamova R, Lefterov I. Gene co-expression networks identify Trem2 and Tyrobp as major hubs in human APOE expressing mice following traumatic brain injury. Neurobiology of Disease. PMID 28502803 DOI: 10.1016/J.Nbd.2017.05.006 |
0.39 |
|
| 2017 |
Carter AY, Letronne F, Fitz NF, Mounier A, Wolfe CM, Nam KN, Reeves VL, Kamboh H, Lefterov I, Koldamova R. Liver X receptor agonist treatment significantly affects phenotype and transcriptome of APOE3 and APOE4 Abca1 haplo-deficient mice. Plos One. 12: e0172161. PMID 28241068 DOI: 10.1371/Journal.Pone.0172161 |
0.527 |
|
| 2017 |
Fitz NF, Carter AY, Tapias V, Castranio EL, Kodali R, Lefterov I, Koldamova R. ABCA1 Deficiency Affects Basal Cognitive Deficits and Dendritic Density in Mice. Journal of Alzheimer's Disease : Jad. PMID 28106559 DOI: 10.3233/Jad-161056 |
0.499 |
|
| 2017 |
Nam KN, Fitz NF, Wolfe CM, Mounier A, Schug J, Lefterov I, Koldamova R. The Dynamic Changes Of Microglial Transcriptome Associated With Age And Amyloid Pathology Alzheimers & Dementia. 13: 655. DOI: 10.1016/J.Jalz.2017.06.776 |
0.32 |
|
| 2017 |
Fitz NF, Wolfe CM, Nam KN, Letronne F, Castranio EL, Playso B, Schug J, Lefterov I, Koldamova R. APOE ISOFORM-SPECIFIC EFFECTS ON AMYLOID-β-INDUCED PATHOLOGY: MICROGLIAL FUNCTION, NEURONAL INTEGRITY AND COGNITIVE DECLINE Alzheimers & Dementia. 13: 315. DOI: 10.1016/J.Jalz.2017.06.256 |
0.354 |
|
| 2017 |
Nam KN, Fitz NF, Wolfe CM, Schug J, Lefterov I, Koldamova R. SHOTGUN LIPIDOMICS AND RNA-SEQ REVEAL EXTENSIVE CHANGES IN CARDIOLIPIN AND PHOSPHOLIPID PATHWAYS IN BRAINS OF APOEε3/3, APOEε3/4 AND APOEε4/4 ALZHEIMER'S DISEASE PATIENTS Alzheimers & Dementia. 13: 302. DOI: 10.1016/J.Jalz.2017.06.222 |
0.345 |
|
| 2016 |
Nam KN, Mounier A, Fitz NF, Wolfe C, Schug J, Lefterov I, Koldamova R. RXR controlled regulatory networks identified in mouse brain counteract deleterious effects of Aβ oligomers. Scientific Reports. 6: 24048. PMID 27051978 DOI: 10.1038/Srep24048 |
0.521 |
|
| 2016 |
Fitz NF, Carter AY, Nam KN, Castranio EL, Mounier A, Wolfe CM, Lefterov I, Koldamova R. Impact Of Apoe Polymorphisms On Amyloid-Beta Oligomerization And Associated Cognitive Decline Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.2155 |
0.35 |
|
| 2016 |
Fitz NF, Nam KN, Wolfe CM, Mounier A, Schug J, Lefterov I, Koldamova R. High-Fat Diet Affects Inflammation And Increases Trem2 Level In App Mice Alzheimers & Dementia. 12: 655. DOI: 10.1016/J.Jalz.2016.06.1483 |
0.359 |
|
| 2015 |
Fitz NF, Tapias V, Cronican AA, Castranio EL, Saleem M, Carter AY, Lefterova M, Lefterov I, Koldamova R. Opposing effects of Apoe/Apoa1 double deletion on amyloid-β pathology and cognitive performance in APP mice. Brain : a Journal of Neurology. PMID 26510953 DOI: 10.1093/Brain/Awv293 |
0.53 |
|
| 2015 |
Mounier A, Georgiev D, Nam KN, Fitz NF, Castranio EL, Wolfe CM, Cronican AA, Schug J, Lefterov I, Koldamova R. Bexarotene-activated retinoid X receptors regulate neuronal differentiation and dendritic complexity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 11862-11876. PMID 26311769 DOI: 10.1523/Jneurosci.1001-15.2015 |
0.39 |
|
| 2015 |
Lefterov I, Schug J, Mounier A, Nam KN, Fitz NF, Koldamova R. RNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment. Neurobiology of Disease. 82: 132-40. PMID 26071899 DOI: 10.1016/J.Nbd.2015.05.019 |
0.49 |
|
| 2014 |
Koldamova R, Fitz NF, Lefterov I. ATP-binding cassette transporter A1: from metabolism to neurodegeneration. Neurobiology of Disease. 72: 13-21. PMID 24844148 DOI: 10.1016/J.Nbd.2014.05.007 |
0.466 |
|
| 2014 |
Fitz NF, Castranio EL, Carter AY, Kodali R, Lefterov I, Koldamova R. Improvement of memory deficits and amyloid-β clearance in aged APP23 mice treated with a combination of anti-amyloid-β antibody and LXR agonist. Journal of Alzheimer's Disease : Jad. 41: 535-49. PMID 24643138 DOI: 10.3233/Jad-132789 |
0.539 |
|
| 2014 |
Koldamova R, Schug J, Lefterova M, Cronican AA, Fitz NF, Davenport FA, Carter A, Castranio EL, Lefterov I. Genome-wide approaches reveal EGR1-controlled regulatory networks associated with neurodegeneration. Neurobiology of Disease. 63: 107-14. PMID 24269917 DOI: 10.1016/J.Nbd.2013.11.005 |
0.443 |
|
| 2014 |
Fitz N, Castranio E, Carter A, Lefterov I, Koldamova R. P1-074: EFFECTS OF APOLIPOPROTEIN E ON COGNITIVE PERFORMANCE AND AMYLOID OLIGOMERIZATION IN A MOUSE MODEL Alzheimer's & Dementia. 10: P330-P330. DOI: 10.1016/J.Jalz.2014.05.310 |
0.368 |
|
| 2013 |
Fitz NF, Cronican AA, Lefterov I, Koldamova R. Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models". Science (New York, N.Y.). 340: 924-c. PMID 23704552 DOI: 10.1126/science.1235809 |
0.427 |
|
| 2013 |
Cronican AA, Fitz NF, Carter A, Saleem M, Shiva S, Barchowsky A, Koldamova R, Schug J, Lefterov I. Genome-wide alteration of histone H3K9 acetylation pattern in mouse offspring prenatally exposed to arsenic. Plos One. 8: e53478. PMID 23405071 DOI: 10.1371/Journal.Pone.0053478 |
0.313 |
|
| 2012 |
Fitz NF, Cronican AA, Saleem M, Fauq AH, Chapman R, Lefterov I, Koldamova R. Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 13125-36. PMID 22993429 DOI: 10.1523/Jneurosci.1937-12.2012 |
0.557 |
|
| 2012 |
Lefterov I, Koldamova R, Fitz N. P4-239: ABCA1 deficiency differentially affects the amyloid phenotype of APOE-ε3- and APOE-ε4-targeted replacement mice Alzheimer's & Dementia. 8: P718-P718. DOI: 10.1016/J.Jalz.2012.05.2103 |
0.469 |
|
| 2011 |
Lefterov I, Lefterova M, Chronican A, Fitz N, Schug J, Koldamova R. P4-016: Egr1 binding and histone modification mapping in brain of mouse model of AD Alzheimer's & Dementia. 7: S703-S704. DOI: 10.1016/J.Jalz.2011.05.2034 |
0.372 |
|
| 2011 |
Fitz N, Chronican A, Kodali R, Wetzel R, Lefterov I, Koldamova R. ABCA1 deficiency decreases Amyloid clearance and increases Amyloid aggregation in Alzheimer's disease mouse model Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.2032 |
0.456 |
|
| 2010 |
Lefterov I, Fitz NF, Cronican AA, Fogg A, Lefterov P, Kodali R, Wetzel R, Koldamova R. Apolipoprotein A-I deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1DeltaE9 mice. The Journal of Biological Chemistry. 285: 36945-57. PMID 20739292 DOI: 10.1074/Jbc.M110.127738 |
0.542 |
|
| 2010 |
Fitz NF, Cronican A, Pham T, Fogg A, Fauq AH, Chapman R, Lefterov I, Koldamova R. Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6862-72. PMID 20484628 DOI: 10.1523/Jneurosci.1051-10.2010 |
0.493 |
|
| 2010 |
Koldamova R, Fitz NF, Lefterov I. The role of ATP-binding cassette transporter A1 in Alzheimer's disease and neurodegeneration. Biochimica Et Biophysica Acta. 1801: 824-30. PMID 20188211 DOI: 10.1016/J.Bbalip.2010.02.010 |
0.464 |
|
| 2010 |
Cronican AA, Fitz NF, Pham T, Fogg A, Kifer B, Koldamova R, Lefterov I. Proton pump inhibitor lansoprazole is a nuclear liver X receptor agonist. Biochemical Pharmacology. 79: 1310-6. PMID 20060385 DOI: 10.1016/J.Bcp.2009.12.018 |
0.428 |
|
| 2009 |
Cohen AD, Ikonomovic MD, Abrahamson EE, Paljug WR, Dekosky ST, Lefterov IM, Koldamova RP, Shao L, Debnath ML, Mason NS, Mathis CA, Klunk WE. Anti-Amyloid Effects of Small Molecule Aβ-Binding Agents in PS1/APP Mice. Letters in Drug Design & Discovery. 6: 437. PMID 20119496 DOI: 10.2174/157018009789057526 |
0.431 |
|
| 2009 |
Lefterov I, Fitz NF, Cronican A, Lefterov P, Staufenbiel M, Koldamova R. Memory deficits in APP23/Abca1+/- mice correlate with the level of Aβ oligomers. Asn Neuro. 1. PMID 19570031 DOI: 10.1042/An20090015 |
0.516 |
|
| 2009 |
Lefterov I. S5-02-03: Role of Abca1, ApoE and ApoA-I in Alzheimer's disease pathogenesis: Lessons from complex animal models Alzheimer's & Dementia. 5: P168-P168. DOI: 10.1016/J.Jalz.2009.05.579 |
0.349 |
|
| 2009 |
Koldamova R, Fitz N, Cronican A, Fogg A, Eggelstone S, Tulloch T, Carter A, Lefterov I. P2-160: Critical role of Abca1 in maintaining functional apoE and apoA-I and their impact on A-beta aggregation and clearance from brain Alzheimer's & Dementia. 5: P308-P308. DOI: 10.1016/J.Jalz.2009.04.472 |
0.371 |
|
| 2007 |
Lefterov I, Bookout A, Wang Z, Staufenbiel M, Mangelsdorf D, Koldamova R. Expression profiling in APP23 mouse brain: inhibition of Abeta amyloidosis and inflammation in response to LXR agonist treatment. Molecular Neurodegeneration. 2: 20. PMID 17953774 DOI: 10.1186/1750-1326-2-20 |
0.465 |
|
| 2007 |
Koldamova R, Lefterov I. Role of LXR and ABCA1 in the pathogenesis of Alzheimer's disease - implications for a new therapeutic approach. Current Alzheimer Research. 4: 171-8. PMID 17430243 DOI: 10.2174/156720507780362227 |
0.467 |
|
| 2006 |
Koldamova R, Lefterov I, Fitz NF, Nam KN, Wolfe CM, Iordanova B, Koldamova R, Lefterov I. P4-051: EFFECT OF APOE ISOFORM ON MICROGLIAL RESPONSE TO AMYLOID-BETA Alzheimer's & Dementia. 14: P1453-P1453. DOI: 10.1016/J.Jalz.2018.06.2454 |
0.368 |
|
| 2005 |
Klunk WE, Lopresti BJ, Ikonomovic MD, Lefterov IM, Koldamova RP, Abrahamson EE, Debnath ML, Holt DP, Huang GF, Shao L, DeKosky ST, Price JC, Mathis CA. Binding of the positron emission tomography tracer Pittsburgh compound-B reflects the amount of amyloid-beta in Alzheimer's disease brain but not in transgenic mouse brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10598-606. PMID 16291932 DOI: 10.1523/Jneurosci.2990-05.2005 |
0.365 |
|
| 2005 |
Koldamova R, Staufenbiel M, Lefterov I. Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice. The Journal of Biological Chemistry. 280: 43224-35. PMID 16207713 DOI: 10.1074/Jbc.M504513200 |
0.56 |
|
| 2005 |
Koldamova RP, Lefterov IM, Staufenbiel M, Wolfe D, Huang S, Glorioso JC, Walter M, Roth MG, Lazo JS. The liver X receptor ligand T0901317 decreases amyloid beta production in vitro and in a mouse model of Alzheimer's disease. The Journal of Biological Chemistry. 280: 4079-88. PMID 15557325 DOI: 10.1074/Jbc.M411420200 |
0.357 |
|
| 2005 |
Klunk WE, Lopresti BJ, Debnath ML, Huang G, Shao L, Lefterov I, Koldamova R, Ikonomovic MD, DeKosky ST, Mathis CA. Low binding of the amyloid PET tracer, PIB, to transgenic PS1/APP mouse brain compared to human AD brain explained by Bmax Alzheimers & Dementia. 1. DOI: 10.1016/J.Jalz.2005.06.170 |
0.442 |
|
| 2004 |
Klunk WE, Lopresti BJ, Debnath ML, Holt DP, Wang Y, Huang G, Shao L, Lefterov I, Koldamova R, Ikonomovic M, DeKosky ST, Mathis CA. P2-031 Amyloid deposits in transgenic PS1/APP mice do not bind the amyloid pet tracer, PIB, in the same manner as human brain amyloid Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80779-6 |
0.49 |
|
| 2001 |
Koldamova RP, Lefterov IM, Lefterova MI, Lazo JS. Apolipoprotein A-I directly interacts with amyloid precursor protein and inhibits Aβ aggregation and toxicity Biochemistry. 40: 3553-3560. PMID 11297421 DOI: 10.1021/bi002186k |
0.328 |
|
| 2000 |
Lefterov IM, Koldamova RP, Lazo JS. Human bleomycin hydrolase regulates the secretion of amyloid precursor protein Faseb Journal. 14: 1837-1847. PMID 10973933 |
0.338 |
|
| Show low-probability matches. |