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A. K. McClendon, Ph.D. - Publications

Affiliations: 
2006 Vanderbilt University, Nashville, TN 
Area:
Biochemistry
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10/25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Dean JL, McClendon AK, Knudsen ES. Modification of the DNA damage response by therapeutic CDK4/6 inhibition. The Journal of Biological Chemistry. 287: 29075-87. PMID 22733811 DOI: 10.1074/jbc.M112.365494  0.508
2010 McClendon AK, Dean JL, Ertel A, Knudsen ES. Differential impact of tumor suppressor pathways on DNA damage response and therapy-induced transformation in a mouse primary cell model. Plos One. 5: e8558. PMID 20049321 DOI: 10.1371/journal.pone.0008558  0.303
2008 McClendon AK, Gentry AC, Dickey JS, Brinch M, Bendsen S, Andersen AH, Osheroff N. Bimodal recognition of DNA geometry by human topoisomerase II alpha: preferential relaxation of positively supercoiled DNA requires elements in the C-terminal domain. Biochemistry. 47: 13169-78. PMID 19053267 DOI: 10.1021/Bi800453H  0.596
2008 Braden WA, McClendon AK, Knudsen ES. Cyclin-dependent kinase 4/6 activity is a critical determinant of pre-replication complex assembly. Oncogene. 27: 7083-93. PMID 18776921 DOI: 10.1038/onc.2008.319  0.329
2007 Frøhlich RF, Veigaard C, Andersen FF, McClendon AK, Gentry AC, Andersen AH, Osheroff N, Stevnsner T, Knudsen BR. Tryptophane-205 of human topoisomerase I is essential for camptothecin inhibition of negative but not positive supercoil removal. Nucleic Acids Research. 35: 6170-80. PMID 17827209 DOI: 10.1093/Nar/Gkm669  0.683
2007 McClendon AK, Osheroff N. DNA topoisomerase II, genotoxicity, and cancer. Mutation Research. 623: 83-97. PMID 17681352 DOI: 10.1016/J.Mrfmmm.2007.06.009  0.737
2006 McClendon AK, Dickey JS, Osheroff N. Ability of viral topoisomerase II to discern the handedness of supercoiled DNA: bimodal recognition of DNA geometry by type II enzymes. Biochemistry. 45: 11674-80. PMID 16981727 DOI: 10.1021/Bi0520838  0.739
2006 McClendon AK, Osheroff N. The geometry of DNA supercoils modulates topoisomerase-mediated DNA cleavage and enzyme response to anticancer drugs. Biochemistry. 45: 3040-50. PMID 16503659 DOI: 10.1021/Bi051987Q  0.756
2005 McClendon AK, Rodriguez AC, Osheroff N. Human topoisomerase IIalpha rapidly relaxes positively supercoiled DNA: implications for enzyme action ahead of replication forks. The Journal of Biological Chemistry. 280: 39337-45. PMID 16188892 DOI: 10.1074/Jbc.M503320200  0.805
2004 Sappal DS, McClendon AK, Fleming JA, Thoroddsen V, Connolly K, Reimer C, Blackman RK, Bulawa CE, Osheroff N, Charlton P, Rudolph-Owen LA. Biological characterization of MLN944: a potent DNA binding agent. Molecular Cancer Therapeutics. 3: 47-58. PMID 14749475  0.642
Low-probability matches (unlikely to be authored by this person)
2011 Bourgo RJ, Thangavel C, Ertel A, Bergseid J, McClendon AK, Wilkens L, Witkiewicz AK, Wang JY, Knudsen ES. RB restricts DNA damage-initiated tumorigenesis through an LXCXE-dependent mechanism of transcriptional control. Molecular Cell. 43: 663-72. PMID 21855804 DOI: 10.1016/J.Molcel.2011.06.029  0.292
2010 Reed CA, Mayhew CN, McClendon AK, Knudsen ES. Unique impact of RB loss on hepatic proliferation: tumorigenic stresses uncover distinct pathways of cell cycle control. The Journal of Biological Chemistry. 285: 1089-96. PMID 19887370 DOI: 10.1074/jbc.M109.043380  0.176
2023 Braden WA, McClendon AK, Knudsen ES. Retraction Note: Cyclin-dependent kinase 4/6 activity is a critical determinant of pre-replication complex assembly. Oncogene. 42: 1332. PMID 36949240 DOI: 10.1038/s41388-023-02663-0  0.143
2012 McClendon AK, Dean JL, Rivadeneira DB, Yu JE, Reed CA, Gao E, Farber JL, Force T, Koch WJ, Knudsen ES. CDK4/6 inhibition antagonizes the cytotoxic response to anthracycline therapy. Cell Cycle (Georgetown, Tex.). 11: 2747-55. PMID 22751436 DOI: 10.4161/Cc.21127  0.14
2009 Reed CA, Mayhew CN, McClendon AK, Yang X, Witkiewicz A, Knudsen ES. RB has a critical role in mediating the in vivo checkpoint response, mitigating secondary DNA damage and suppressing liver tumorigenesis initiated by aflatoxin B1. Oncogene. 28: 4434-43. PMID 19838213 DOI: 10.1038/onc.2009.303  0.138
2013 Nussbaum JM, Liu LJ, Hasan SA, Schaub M, McClendon A, Stainier DY, Sakaguchi TF. Homeostatic generation of reactive oxygen species protects the zebrafish liver from steatosis. Hepatology (Baltimore, Md.). 58: 1326-38. PMID 23744565 DOI: 10.1002/hep.26551  0.117
2010 Dean JL, McClendon AK, Stengel KR, Knudsen ES. Modeling the effect of the RB tumor suppressor on disease progression: dependence on oncogene network and cellular context. Oncogene. 29: 68-80. PMID 19802012 DOI: 10.1038/onc.2009.313  0.113
2015 Knudsen ES, McClendon AK, Franco J, Ertel A, Fortina P, Witkiewicz AK. RB loss contributes to aggressive tumor phenotypes in MYC-driven triple negative breast cancer. Cell Cycle (Georgetown, Tex.). 14: 109-22. PMID 25602521 DOI: 10.4161/15384101.2014.967118  0.103
2011 McClendon AK, Dean JL, Ertel A, Fu Z, Rivadeneira DB, Reed CA, Bourgo RJ, Witkiewicz A, Addya S, Mayhew CN, Grimes HL, Fortina P, Knudsen ES. RB and p53 cooperate to prevent liver tumorigenesis in response to tissue damage. Gastroenterology. 141: 1439-50. PMID 21704587 DOI: 10.1053/J.Gastro.2011.06.046  0.096
2024 Singh DJ, Tuscano KM, Ortega AL, Dimri M, Tae K, Lee W, Muslim MA, Rivera Paz IM, Liu JL, Pierce LX, McClendon A, Gibson I, Livesay J, Sakaguchi TF. Forward genetics combined with unsupervised classifications identified zebrafish mutants affecting biliary system formation. Developmental Biology. PMID 38729406 DOI: 10.1016/j.ydbio.2024.05.005  0.096
2012 Dean JL, McClendon AK, Hickey TE, Butler LM, Tilley WD, Witkiewicz AK, Knudsen ES. Therapeutic response to CDK4/6 inhibition in breast cancer defined by ex vivo analyses of human tumors. Cell Cycle (Georgetown, Tex.). 11: 2756-61. PMID 22767154 DOI: 10.4161/cc.21195  0.095
2017 Dimri M, Bilogan C, Pierce LX, Naegele G, Vasanji A, Gibson I, McClendon A, Tae K, Sakaguchi TF. Three-dimensional structural analysis reveals a Cdk5-mediated kinase cascade regulating hepatic biliary network branching in zebrafish. Development (Cambridge, England). 144: 2595-2605. PMID 28720653 DOI: 10.1242/dev.147397  0.089
2013 Comstock CE, Augello MA, Goodwin JF, de Leeuw R, Schiewer MJ, Ostrander WF, Burkhart RA, McClendon AK, McCue PA, Trabulsi EJ, Lallas CD, Gomella LG, Centenera MM, Brody JR, Butler LM, et al. Targeting cell cycle and hormone receptor pathways in cancer. Oncogene. 32: 5481-91. PMID 23708653 DOI: 10.1038/Onc.2013.83  0.085
2010 Dean JL, Thangavel C, McClendon AK, Reed CA, Knudsen ES. Therapeutic CDK4/6 inhibition in breast cancer: key mechanisms of response and failure. Oncogene. 29: 4018-32. PMID 20473330 DOI: 10.1038/onc.2010.154  0.08
2012 Knudsen ES, Pajak TF, Qeenan M, McClendon AK, Armon BD, Schwartz GF, Witkiewicz AK. Retinoblastoma and phosphate and tensin homolog tumor suppressors: impact on ductal carcinoma in situ progression. Journal of the National Cancer Institute. 104: 1825-36. PMID 23197489 DOI: 10.1093/jnci/djs446  0.035
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