Laura Leys - Publications

Affiliations: 
AbbVie Labs 

11 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Gauld S, Jacquet S, Gauvin D, Wallace C, Wang Y, McCarthy R, Goess C, Leys L, Huang S, Su Z, Edelmayer R, Wetter J, Salte K, McGaraughty S, Argiriadi M, et al. Inhibition of IL-23 mediated inflammation with a novel small molecule inverse agonist of RORgt. The Journal of Pharmacology and Experimental Therapeutics. PMID 31375639 DOI: 10.1124/jpet.119.258046  0.6
2019 Leys L, Wang Y, Paulsboe S, Edelmayer R, Salte K, Wetter J, Namovic M, Phillips L, Dunstan R, Gauvin D, Donnelly-Roberts D, Su Z, Honore P, McGaraughty S. Characterization of psoriasiform dermatitis induced by systemic injection of interleukin-23 minicircles in mice. The Journal of Dermatology. PMID 31062408 DOI: 10.1111/1346-8138.14899  0.6
2019 Wang Y, Edelmayer R, Wetter J, Salte K, Gauvin D, Leys L, Paulsboe S, Su Z, Weinberg I, Namovic M, Gauld SB, Honore P, Scott VE, McGaraughty S. Monocytes/Macrophages play a pathogenic role in IL-23 mediated psoriasis-like skin inflammation. Scientific Reports. 9: 5310. PMID 30926837 DOI: 10.1038/s41598-019-41655-7  0.6
2018 Su Z, Paulsboe S, Wetter J, Salte K, Kannan A, Mathew S, Horowitz A, Gerstein C, Namovic M, Todorović V, Seagal J, Edelmayer RM, Viner M, Rinaldi L, Zhou L, ... Leys L, et al. IL-36 receptor antagonistic antibodies inhibit inflammatory responses in preclinical models of psoriasiform dermatitis. Experimental Dermatology. PMID 30417427 DOI: 10.1111/exd.13841  0.6
2018 Gauld SB, Gauvin D, Olson L, Leys L, Paulsboe S, Liu Z, Edelmayer RM, Wetter J, Salte K, Wang Y, Huang S, Honore P, McGaraughty S. Mechanistic and pharmacological assessment of murine IL-23 mediated psoriasiform dermatitis; implications for drug discovery. Journal of Dermatological Science. PMID 30149967 DOI: 10.1016/j.jdermsci.2018.08.001  0.6
2018 Su Z, Widomski D, Nikkel A, Leys L, Namovic M, Donnelly-Roberts D, Gopalakrishnan M, McGaraughty S. Losartan improves renal function and pathology in obese ZSF-1 rats. Journal of Basic and Clinical Physiology and Pharmacology. PMID 29397387 DOI: 10.1515/jbcpp-2017-0157  0.6
2017 McGaraughty S, Chu KL, Xu J, Leys L, Radek RJ, Dart MJ, Gomtsyan A, Schmidt RG, Kym PR, Brederson JD. TRPV3 modulates nociceptive signaling through peripheral and supraspinal sites in rats. Journal of Neurophysiology. jn.00104.2017. PMID 28468993 DOI: 10.1152/jn.00104.2017  0.6
2016 Su Z, Widomski D, Ma J, Namovic M, Nikkel A, Leys L, Olson L, Salte K, Donnelly-Roberts D, Esbenshade T, McGaraughty S. Longitudinal Changes in Measured Glomerular Filtration Rate, Renal Fibrosis and Biomarkers in a Rat Model of Type 2 Diabetic Nephropathy. American Journal of Nephrology. 44: 339-353. PMID 27736813 DOI: 10.1159/000449324  0.6
2016 Zhu CZ, Gopalakrishnan S, Doyle K, Nikkel AL, Olson L, Abraham VC, Leys L, Widomski D, Salte K, Putman B, Pratt S, Ma J, Su Z, Gopalakrishnan M, Lee CH, et al. A-306989, an inhibitor of adenosine kinase, is renoprotective in rodent models of podocyte, basement membrane, and obstructive injury. European Journal of Pharmacology. PMID 27288879 DOI: 10.1016/j.ejphar.2016.06.012  0.6
2013 Leys LJ, Chu KL, Xu J, Pai M, Yang HS, Robb HM, Jarvis MF, Radek RJ, McGaraughty S. Disturbances in slow-wave sleep are induced by models of bilateral inflammation, neuropathic, and postoperative pain, but not osteoarthritic pain in rats. Pain. 154: 1092-102. PMID 23664655 DOI: 10.1016/j.pain.2013.03.019  0.6
2012 Leys LJ, McGaraughty S, Radek RJ. Rats housed on corncob bedding show less slow-wave sleep. Journal of the American Association For Laboratory Animal Science : Jaalas. 51: 764-8. PMID 23294881  0.6
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