| Year | Citation | Score | |||
|---|---|---|---|---|---|
| 2024 | Moore E, Bell IM, Fraley ME, Burgey CS, White RB, Li CC, Regan CP, Danziger A, McGaraughty SP, Naseri Kouzehgarani G, Salvatore C, Banerjee P. Pharmacologic characterization of atogepant: A potent and selective calcitonin gene-related peptide receptor antagonist. Cephalalgia : An International Journal of Headache. 44: 3331024231226186. PMID 38215228 DOI: 10.1177/03331024231226186 | 0.753 | |||
| 2022 | Patel MV, Peltier HM, Matulenko MA, Koenig JR, C Scanio MJ, Gum RJ, El-Kouhen OF, Fricano MM, Lundgaard GL, Neelands T, Zhang XF, Zhan C, Pai M, Ghoreishi-Haack N, Hudzik T, ... ... McGaraughty S, et al. Discovery of (R)-(3-fluoropyrrolidin-1-yl)(6-((5-(trifluoromethyl)pyridin-2-yl)oxy)quinolin-2-yl)methanone (ABBV-318) and analogs as small molecule Na1.7/ Nav1.8 blockers for the treatment of pain. Bioorganic & Medicinal Chemistry. 63: 116743. PMID 35436748 DOI: 10.1016/j.bmc.2022.116743 | 0.302 | |||
| 2020 | Chu K, Su Z, Wetter J, Namovic M, Leys L, Wang Y, Honore P, McGaraughty S. Characterization of MC903 induced Atopic Dermatitis‐like skin inflammation in mice The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09550 | 0.753 | |||
| 2019 | Leys L, Wang Y, Paulsboe S, Edelmayer R, Salte K, Wetter J, Namovic M, Phillips L, Dunstan R, Gauvin D, Donnelly-Roberts D, Su Z, Honore P, McGaraughty S. Characterization of psoriasiform dermatitis induced by systemic injection of interleukin-23 minicircles in mice. The Journal of Dermatology. PMID 31062408 DOI: 10.1111/1346-8138.14899 | 0.746 | |||
| 2019 | Wang Y, Edelmayer R, Wetter J, Salte K, Gauvin D, Leys L, Paulsboe S, Su Z, Weinberg I, Namovic M, Gauld SB, Honore P, Scott VE, McGaraughty S. Monocytes/Macrophages play a pathogenic role in IL-23 mediated psoriasis-like skin inflammation. Scientific Reports. 9: 5310. PMID 30926837 DOI: 10.1038/S41598-019-41655-7 | 0.722 | |||
| 2018 | Su Z, Paulsboe S, Wetter J, Salte K, Kannan A, Mathew S, Horowitz A, Gerstein C, Namovic M, Todorović V, Seagal J, Edelmayer RM, Viner M, Rinaldi L, Zhou L, ... ... McGaraughty S, et al. IL-36 receptor antagonistic antibodies inhibit inflammatory responses in preclinical models of psoriasiform dermatitis. Experimental Dermatology. PMID 30417427 DOI: 10.1111/Exd.13841 | 0.74 | |||
| 2018 | McGaraughty S, Chu KL, Xu J. Characterization and Pharmacological Modulation of Noci-Responsive Deep Dorsal Horn Neurons Across Diverse Rat Models of Pathological Pain. Journal of Neurophysiology. PMID 30067136 DOI: 10.1152/Jn.00325.2018 | 0.616 | |||
| 2018 | Zhu CZ, Doyle KJ, Nikkel AL, Olsen L, Namovic MT, Salte K, Widomski D, Su Z, Donnelly-Roberts DL, Gopalakrishnan MM, McGaraughty S. Short-term oral gavage administration of adenine induces a model of fibrotic kidney disease in rats. Journal of Pharmacological and Toxicological Methods. PMID 29684554 DOI: 10.1016/j.vascn.2018.04.003 | 0.31 | |||
| 2018 | Brederson JD, Chu KL, Xu J, Nikkel AL, Markosyan S, Jarvis MF, Edelmayer R, Bitner RS, McGaraughty S. Characterization and Comparison of Rat Monosodium Iodoacetate and Medial Meniscal Tear Models of Osteoarthritic Pain. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 29430715 DOI: 10.1002/Jor.23869 | 0.799 | |||
| 2018 | Su Z, Widomski D, Nikkel A, Leys L, Namovic M, Donnelly-Roberts D, Gopalakrishnan M, McGaraughty S. Losartan improves renal function and pathology in obese ZSF-1 rats. Journal of Basic and Clinical Physiology and Pharmacology. PMID 29397387 DOI: 10.1515/Jbcpp-2017-0157 | 0.744 | |||
| 2017 | McGaraughty S, Chu KL, Xu J, Leys L, Radek RJ, Dart MJ, Gomtsyan A, Schmidt RG, Kym PR, Brederson JD. TRPV3 modulates nociceptive signaling through peripheral and supraspinal sites in rats. Journal of Neurophysiology. jn.00104.2017. PMID 28468993 DOI: 10.1152/Jn.00104.2017 | 0.804 | |||
| 2016 | Su Z, Widomski D, Ma J, Namovic M, Nikkel A, Leys L, Olson L, Salte K, Donnelly-Roberts D, Esbenshade T, McGaraughty S. Longitudinal Changes in Measured Glomerular Filtration Rate, Renal Fibrosis and Biomarkers in a Rat Model of Type 2 Diabetic Nephropathy. American Journal of Nephrology. 44: 339-353. PMID 27736813 DOI: 10.1159/000449324 | 0.757 | |||
| 2016 | Zhu CZ, Gopalakrishnan S, Doyle K, Nikkel AL, Olson L, Abraham VC, Leys L, Widomski D, Salte K, Putman B, Pratt S, Ma J, Su Z, Gopalakrishnan M, Lee CH, ... McGaraughty SP, et al. A-306989, an inhibitor of adenosine kinase, is renoprotective in rodent models of podocyte, basement membrane, and obstructive injury. European Journal of Pharmacology. PMID 27288879 DOI: 10.1016/J.Ejphar.2016.06.012 | 0.762 | |||
| 2016 | Gomtsyan AR, Schmidt RG, Bayburt EK, Gfesser GA, Voight EA, Daanen JF, Schmidt DL, Cowart MD, Liu H, Altenbach RJ, Kort ME, Clapham B, Cox PB, Shrestha A, Henry R, ... ... McGaraughty SP, et al. Synthesis and Pharmacology of (Pyridin-2-yl)methanol Derivatives as Novel and Selective Transient Receptor Potential Vanilloid 3 (TRPV3) Antagonists. Journal of Medicinal Chemistry. PMID 27077528 DOI: 10.1021/Acs.Jmedchem.6B00287 | 0.764 | |||
| 2015 | Chu KL, Xu J, Frost J, Li L, Gomez E, Dart MJ, Jarvis MF, Meyer MD, McGaraughty S. A selective α2 B adrenoceptor agonist (A-1262543) and duloxetine modulate nociceptive neurones in the medial prefrontal cortex, but not in the spinal cord of neuropathic rats. European Journal of Pain (London, England). 19: 649-60. PMID 25154730 DOI: 10.1002/ejp.586 | 0.539 | |||
| 2015 | Jarvis MF, Scott VE, McGaraughty S, Chu KL, Xu J, Niforatos W, Milicic I, Joshi S, Zhang Q, Xia Z. Corrigendum to “A peripherally acting, selective T-type calcium channel blocker, ABT-639, effectively reduces nociceptive and neuropathic pain in rats” [Biochem. Pharmacol. 89 (4) (2014) 536–544] Biochemical Pharmacology. 94: 227. DOI: 10.1016/J.Bcp.2015.02.008 | 0.54 | |||
| 2014 | Swensen AM, Niforatos W, Lee CH, Jarvis MF, McGaraughty S. Characterization of the triazine, T4, a representative from a novel series of CaV2 inhibitors with strong state-dependence, poor use-dependence, and distinctively fast kinetics. European Journal of Pharmacology. 745: 234-42. PMID 25446431 DOI: 10.1016/j.ejphar.2014.10.037 | 0.688 | |||
| 2014 | Jarvis MF, Scott VE, McGaraughty S, Chu KL, Xu J, Niforatos W, Milicic I, Joshi S, Zhang Q, Xia Z. A peripherally acting, selective T-type calcium channel blocker, ABT-639, effectively reduces nociceptive and neuropathic pain in rats. Biochemical Pharmacology. 89: 536-44. PMID 24726441 DOI: 10.1016/J.Bcp.2014.03.015 | 0.588 | |||
| 2014 | Zhu CZ, Vortherms TA, Zhang M, Xu J, Swensen AM, Niforatos W, Neelands T, Milicic I, Lewis LG, Zhong C, Gauvin D, Mikusa J, Zhan C, Pai M, Roderwald V, ... ... McGaraughty S, et al. Mechanistic insights into the analgesic efficacy of A-1264087, a novel neuronal Ca(2+) channel blocker that reduces nociception in rat preclinical pain models. The Journal of Pain : Official Journal of the American Pain Society. 15: 387.e1-14. PMID 24374196 DOI: 10.1016/J.Jpain.2013.12.002 | 0.782 | |||
| 2014 | Xu J, Chu KL, Zhu CZ, Niforatos W, Swensen A, Searle X, Lee L, Jarvis MF, McGaraughty S. A mixed Ca2+ channel blocker, A-1264087, utilizes peripheral and spinal mechanisms to inhibit spinal nociceptive transmission in a rat model of neuropathic pain. Journal of Neurophysiology. 111: 394-404. PMID 24155005 DOI: 10.1152/Jn.00463.2013 | 0.786 | |||
| 2013 | Leys LJ, Chu KL, Xu J, Pai M, Yang HS, Robb HM, Jarvis MF, Radek RJ, McGaraughty S. Disturbances in slow-wave sleep are induced by models of bilateral inflammation, neuropathic, and postoperative pain, but not osteoarthritic pain in rats. Pain. 154: 1092-102. PMID 23664655 DOI: 10.1016/J.Pain.2013.03.019 | 0.775 | |||
| 2012 | Leys LJ, McGaraughty S, Radek RJ. Rats housed on corncob bedding show less slow-wave sleep. Journal of the American Association For Laboratory Animal Science : Jaalas. 51: 764-8. PMID 23294881 | 0.727 | |||
| 2012 | McGaraughty S, Chu KL, Cowart MD, Brioni JD. Antagonism of supraspinal histamine H3 receptors modulates spinal neuronal activity in neuropathic rats. The Journal of Pharmacology and Experimental Therapeutics. 343: 13-20. PMID 22729221 DOI: 10.1124/jpet.112.194761 | 0.592 | |||
| 2012 | Swensen AM, Niforatos W, Vortherms TA, Perner RJ, Li T, Schrimpf MR, Scott VE, Lee L, Jarvis MF, McGaraughty S. An automated electrophysiological assay for differentiating Ca(v)2.2 inhibitors based on state dependence and kinetics. Assay and Drug Development Technologies. 10: 542-50. PMID 22428804 DOI: 10.1089/adt.2011.437 | 0.678 | |||
| 2012 | Xu J, Chu KL, Brederson JD, Jarvis MF, McGaraughty S. Spontaneous firing and evoked responses of spinal nociceptive neurons are attenuated by blockade of P2X3 and P2X2/3 receptors in inflamed rats. Journal of Neuroscience Research. 90: 1597-606. PMID 22422599 DOI: 10.1002/Jnr.23042 | 0.82 | |||
| 2012 | Brederson JD, Chu KL, Reilly RM, Brown BS, Kym PR, Jarvis MF, McGaraughty S. TRPV1 antagonist, A-889425, inhibits mechanotransmission in a subclass of rat primary afferent neurons following peripheral inflammation. Synapse (New York, N.Y.). 66: 187-95. PMID 21953601 DOI: 10.1002/Syn.20992 | 0.795 | |||
| 2011 | Zhang XF, Han P, Neelands TR, McGaraughty S, Honore P, Surowy CS, Zhang D. Coexpression and activation of TRPV1 suppress the activity of the KCNQ2/3 channel. The Journal of General Physiology. 138: 341-52. PMID 21844219 DOI: 10.1085/Jgp.201110618 | 0.409 | |||
| 2011 | Chen J, Joshi SK, DiDomenico S, Perner RJ, Mikusa JP, Gauvin DM, Segreti JA, Han P, Zhang XF, Niforatos W, Bianchi BR, Baker SJ, Zhong C, Simler GH, McDonald HA, ... ... McGaraughty SP, et al. Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation. Pain. 152: 1165-72. PMID 21402443 DOI: 10.1016/J.Pain.2011.01.049 | 0.502 | |||
| 2011 | Rowbotham MC, Nothaft W, Duan WR, Wang Y, Faltynek C, McGaraughty S, Chu KL, Svensson P. Oral and cutaneous thermosensory profile of selective TRPV1 inhibition by ABT-102 in a randomized healthy volunteer trial. Pain. 152: 1192-200. PMID 21377273 DOI: 10.1016/J.Pain.2011.01.051 | 0.487 | |||
| 2011 | Chu KL, Chandran P, Joshi SK, Jarvis MF, Kym PR, McGaraughty S. TRPV1-related modulation of spinal neuronal activity and behavior in a rat model of osteoarthritic pain. Brain Research. 1369: 158-66. PMID 21047496 DOI: 10.1016/j.brainres.2010.10.101 | 0.62 | |||
| 2010 | Boyce-Rustay JM, Simler GH, McGaraughty S, Chu KL, Wensink EJ, Vasudevan A, Honore P. Characterization of Fasudil in preclinical models of pain. The Journal of Pain : Official Journal of the American Pain Society. 11: 941-9. PMID 20338818 DOI: 10.1016/j.jpain.2009.12.014 | 0.563 | |||
| 2010 | McGaraughty S, Chu KL, Perner RJ, Didomenico S, Kort ME, Kym PR. TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats. Molecular Pain. 6: 14. PMID 20205719 DOI: 10.1186/1744-8069-6-14 | 0.612 | |||
| 2009 | McGaraughty S, Segreti JA, Fryer RM, Brown BS, Faltynek CR, Kym PR. Antagonism of TRPV1 receptors indirectly modulates activity of thermoregulatory neurons in the medial preoptic area of rats. Brain Research. 1268: 58-67. PMID 19236852 DOI: 10.1016/j.brainres.2009.02.018 | 0.41 | |||
| 2009 | McGaraughty S, Chu KL, Dart MJ, Yao BB, Meyer MD. A CB(2) receptor agonist, A-836339, modulates wide dynamic range neuronal activity in neuropathic rats: contributions of spinal and peripheral CB(2) receptors. Neuroscience. 158: 1652-61. PMID 19063946 DOI: 10.1016/j.neuroscience.2008.11.015 | 0.562 | |||
| 2008 | McGaraughty S, Chu KL, Brown BS, Zhu CZ, Zhong C, Joshi SK, Honore P, Faltynek CR, Jarvis MF. Contributions of central and peripheral TRPV1 receptors to mechanically evoked and spontaneous firing of spinal neurons in inflamed rats. Journal of Neurophysiology. 100: 3158-66. PMID 18829846 DOI: 10.1152/jn.90768.2008 | 0.621 | |||
| 2008 | Surowy CS, Neelands TR, Bianchi BR, McGaraughty S, El Kouhen R, Han P, Chu KL, McDonald HA, Vos M, Niforatos W, Bayburt EK, Gomtsyan A, Lee CH, Honore P, Sullivan JP, et al. (R)-(5-tert-butyl-2,3-dihydro-1H-inden-1-yl)-3-(1H-indazol-4-yl)-urea (ABT-102) blocks polymodal activation of transient receptor potential vanilloid 1 receptors in vitro and heat-evoked firing of spinal dorsal horn neurons in vivo. The Journal of Pharmacology and Experimental Therapeutics. 326: 879-88. PMID 18515644 DOI: 10.1124/Jpet.108.138511 | 0.615 | |||
| 2008 | McGaraughty S, Chu KL, Scanio MJ, Kort ME, Faltynek CR, Jarvis MF. A selective Nav1.8 sodium channel blocker, A-803467 [5-(4-chlorophenyl-N-(3,5-dimethoxyphenyl)furan-2-carboxamide], attenuates spinal neuronal activity in neuropathic rats. The Journal of Pharmacology and Experimental Therapeutics. 324: 1204-11. PMID 18089840 DOI: 10.1124/jpet.107.134148 | 0.606 | |||
| 2008 | Chin CL, Pauly JR, Surber BW, Skoubis PD, McGaraughty S, Hradil VP, Luo Y, Cox BF, Fox GB. Pharmacological MRI in awake rats predicts selective binding of alpha4beta2 nicotinic receptors. Synapse (New York, N.Y.). 62: 159-68. PMID 18081183 DOI: 10.1002/Syn.20474 | 0.773 | |||
| 2008 | Donnelly-Roberts D, McGaraughty S, Shieh CC, Honore P, Jarvis MF. Painful purinergic receptors. The Journal of Pharmacology and Experimental Therapeutics. 324: 409-15. PMID 18042830 DOI: 10.1124/jpet.106.105890 | 0.395 | |||
| 2007 | Jarvis MF, Honore P, Shieh CC, Chapman M, Joshi S, Zhang XF, Kort M, Carroll W, Marron B, Atkinson R, Thomas J, Liu D, Krambis M, Liu Y, McGaraughty S, et al. A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat. Proceedings of the National Academy of Sciences of the United States of America. 104: 8520-5. PMID 17483457 DOI: 10.1073/Pnas.0611364104 | 0.528 | |||
| 2007 | McGaraughty S, Chu KL, Namovic MT, Donnelly-Roberts DL, Harris RR, Zhang XF, Shieh CC, Wismer CT, Zhu CZ, Gauvin DM, Fabiyi AC, Honore P, Gregg RJ, Kort ME, Nelson DW, et al. P2X7-related modulation of pathological nociception in rats. Neuroscience. 146: 1817-28. PMID 17478048 DOI: 10.1016/j.neuroscience.2007.03.035 | 0.642 | |||
| 2006 | Chin CL, Fox GB, Hradil VP, Osinski MA, McGaraughty SP, Skoubis PD, Cox BF, Luo Y. Pharmacological MRI in awake rats reveals neural activity in area postrema and nucleus tractus solitarius: relevance as a potential biomarker for detecting drug-induced emesis. Neuroimage. 33: 1152-60. PMID 17023182 DOI: 10.1016/J.Neuroimage.2006.06.059 | 0.765 | |||
| 2006 | El-Kouhen O, Lehto SG, Pan JB, Chang R, Baker SJ, Zhong C, Hollingsworth PR, Mikusa JP, Cronin EA, Chu KL, McGaraughty SP, Uchic ME, Miller LN, Rodell NM, Patel M, et al. Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: effects of A-841720, a novel non-competitive mGluR1 receptor antagonist. British Journal of Pharmacology. 149: 761-74. PMID 17016515 DOI: 10.1038/sj.bjp.0706877 | 0.522 | |||
| 2006 | Skoubis PD, Hradil V, Chin CL, Luo Y, Fox GB, McGaraughty S. Mapping brain activity following administration of a nicotinic acetylcholine receptor agonist, ABT-594, using functional magnetic resonance imaging in awake rats. Neuroscience. 137: 583-91. PMID 16289887 DOI: 10.1016/J.Neuroscience.2005.08.072 | 0.768 | |||
| 2006 | McGaraughty S, Chu KL, Faltynek CR, Jarvis MF. Systemic and site-specific effects of A-425619, a selective TRPV1 receptor antagonist, on wide dynamic range neurons in CFA-treated and uninjured rats. Journal of Neurophysiology. 95: 18-25. PMID 16162831 DOI: 10.1152/jn.00560.2005 | 0.611 | |||
| 2006 | McGaraughty S, Jarvis MF. Purinergic control of neuropathic pain Drug Development Research. 67: 376-388. DOI: 10.1002/ddr.20101 | 0.415 | |||
| 2005 | McGaraughty S, Honore P, Wismer CT, Mikusa J, Zhu CZ, McDonald HA, Bianchi B, Faltynek CR, Jarvis MF. Endogenous opioid mechanisms partially mediate P2X3/P2X2/3-related antinociception in rat models of inflammatory and chemogenic pain but not neuropathic pain. British Journal of Pharmacology. 146: 180-8. PMID 16041397 DOI: 10.1038/sj.bjp.0706346 | 0.409 | |||
| 2005 | McGaraughty S, Cowart M, Jarvis MF, Berman RF. Anticonvulsant and antinociceptive actions of novel adenosine kinase inhibitors. Current Topics in Medicinal Chemistry. 5: 43-58. PMID 15638777 DOI: 10.2174/1568026053386845 | 0.351 | |||
| 2004 | Chu KL, Faltynek CR, Jarvis MF, McGaraughty S. Increased WDR spontaneous activity and receptive field size in rats following a neuropathic or inflammatory injury: implications for mechanical sensitivity. Neuroscience Letters. 372: 123-6. PMID 15531101 DOI: 10.1016/j.neulet.2004.09.025 | 0.552 | |||
| 2004 | McGaraughty S, Farr DA, Heinricher MM. Lesions of the periaqueductal gray disrupt input to the rostral ventromedial medulla following microinjections of morphine into the medial or basolateral nuclei of the amygdala. Brain Research. 1009: 223-7. PMID 15120601 DOI: 10.1016/j.brainres.2004.02.048 | 0.625 | |||
| 2003 | McGaraughty S, Wismer CT, Zhu CZ, Mikusa J, Honore P, Chu KL, Lee CH, Faltynek CR, Jarvis MF. Effects of A-317491, a novel and selective P2X3/P2X2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration. British Journal of Pharmacology. 140: 1381-8. PMID 14623769 DOI: 10.1038/sj.bjp.0705574 | 0.588 | |||
| 2003 | Zheng GZ, Mao Y, Lee CH, Pratt JK, Koenig JR, Perner RJ, Cowart MD, Gfesser GA, McGaraughty S, Chu KL, Zhu C, Yu H, Kohlhaas K, Alexander KM, Wismer CT, et al. Adenosine kinase inhibitors: polar 7-substitutent of pyridopyrimidine derivatives improving their locomotor selectivity. Bioorganic & Medicinal Chemistry Letters. 13: 3041-4. PMID 12941329 DOI: 10.1016/S0960-894X(03)00642-5 | 0.506 | |||
| 2003 | McGaraughty S, Chu KL, Bitner RS, Martino B, El Kouhen R, Han P, Nikkel AL, Burgard EC, Faltynek CR, Jarvis MF. Capsaicin infused into the PAG affects rat tail flick responses to noxious heat and alters neuronal firing in the RVM. Journal of Neurophysiology. 90: 2702-10. PMID 12815018 DOI: 10.1152/Jn.00433.2003 | 0.595 | |||
| 2003 | Wismer CT, Faltynek CR, Jarvis MF, McGaraughty S. Distinct neurochemical mechanisms are activated following administration of different P2X receptor agonists into the hindpaw of a rat. Brain Research. 965: 187-93. PMID 12591137 DOI: 10.1016/S0006-8993(02)04193-8 | 0.374 | |||
| 2002 | Jarvis MF, Burgard EC, McGaraughty S, Honore P, Lynch K, Brennan TJ, Subieta A, Van Biesen T, Cartmell J, Bianchi B, Niforatos W, Kage K, Yu H, Mikusa J, Wismer CT, et al. A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat. Proceedings of the National Academy of Sciences of the United States of America. 99: 17179-84. PMID 12482951 DOI: 10.1073/Pnas.252537299 | 0.593 | |||
| 2002 | Jarvis MF, Mikusa J, Chu KL, Wismer CT, Honore P, Kowaluk EA, McGaraughty S. Comparison of the ability of adenosine kinase inhibitors and adenosine receptor agonists to attenuate thermal hyperalgesia and reduce motor performance in rats. Pharmacology, Biochemistry, and Behavior. 73: 573-81. PMID 12151032 DOI: 10.1016/S0091-3057(02)00840-7 | 0.54 | |||
| 2002 | McGaraughty S, Heinricher MM. Microinjection of morphine into various amygdaloid nuclei differentially affects nociceptive responsiveness and RVM neuronal activity. Pain. 96: 153-62. PMID 11932071 DOI: 10.1016/S0304-3959(01)00440-7 | 0.647 | |||
| 2002 | Jarvis MF, Yu H, McGaraughty S, Wismer CT, Mikusa J, Zhu C, Chu K, Kohlhaas K, Cowart M, Lee CH, Stewart AO, Cox BF, Polakowski J, Kowaluk EA. Analgesic and anti-inflammatory effects of A-286501, a novel orally active adenosine kinase inhibitor. Pain. 96: 107-18. PMID 11932067 DOI: 10.1016/S0304-3959(01)00435-3 | 0.572 | |||
| 2001 | McGaraughty S, Cowart M, Jarvis MF. Recent developments in the discovery of novel adenosine kinase inhibitors: mechanism of action and therapeutic potential. Cns Drug Reviews. 7: 415-32. PMID 11830758 DOI: 10.1111/J.1527-3458.2001.Tb00208.X | 0.351 | |||
| 2001 | Zheng GZ, Lee C, Pratt JK, Perner RJ, Jiang MQ, Gomtsyan A, Matulenko MA, Mao Y, Koenig JR, Kim KH, Muchmore S, Yu H, Kohlhaas K, Alexander KM, McGaraughty S, et al. Pyridopyrimidine analogues as novel adenosine kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 11: 2071-4. PMID 11514141 DOI: 10.1016/S0960-894X(01)00375-4 | 0.459 | |||
| 2001 | Zhu CZ, Mikusa J, Chu KL, Cowart M, Kowaluk EA, Jarvis MF, McGaraughty S. A-134974: a novel adenosine kinase inhibitor, relieves tactile allodynia via spinal sites of action in peripheral nerve injured rats. Brain Research. 905: 104-10. PMID 11423084 DOI: 10.1016/S0006-8993(01)02512-4 | 0.575 | |||
| 2001 | McGaraughty S, Chu KL, Wismer CT, Mikusa J, Zhu CZ, Cowart M, Kowaluk EA, Jarvis MF. Effects of A-134974, a novel adenosine kinase inhibitor, on carrageenan-induced inflammatory hyperalgesia and locomotor activity in rats: evaluation of the sites of action. The Journal of Pharmacology and Experimental Therapeutics. 296: 501-9. PMID 11160637 | 0.476 | |||
| 2001 | Heinricher MM, McGaraughty S, Tortorici V. Circuitry underlying antiopioid actions of cholecystokinin within the rostral ventromedial medulla. Journal of Neurophysiology. 85: 280-6. PMID 11152727 DOI: 10.1152/Jn.2001.85.1.280 | 0.779 | |||
| 2001 | Cowart M, Lee CH, Gfesser GA, Bayburt EK, Bhagwat SS, Stewart AO, Yu H, Kohlhaas KL, McGaraughty S, Wismer CT, Mikusa J, Zhu C, Alexander KM, Jarvis MF, Kowaluk EA. Structure-activity studies of 5-substituted pyridopyrimidines as adenosine kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 11: 83-6. PMID 11140740 DOI: 10.1016/S0960-894X(00)00602-8 | 0.324 | |||
| 1999 | Heinricher MM, McGaraughty S, Farr DA. The role of excitatory amino acid transmission within the rostral ventromedial medulla in the antinociceptive actions of systemically administered morphine. Pain. 81: 57-65. PMID 10353493 DOI: 10.1016/S0304-3959(98)00271-1 | 0.647 | |||
| 1998 | Heinricher MM, McGaraughty S. Analysis of excitatory amino acid transmission within the rostral ventromedial medulla: implications for circuitry. Pain. 75: 247-55. PMID 9583760 DOI: 10.1016/S0304-3959(97)00226-1 | 0.65 | |||
| 1998 | McGaraughty S, Henry JL. The effects of strychnine, bicuculline, and ketamine on 'immersion-inhibited' dorsal horn convergent neurons in intact and spinalized rats. Brain Research. 784: 63-70. PMID 9518553 DOI: 10.1016/S0006-8993(97)01153-0 | 0.606 | |||
| 1997 | Tsoukatos J, Reinis S, McGaraughty S. Heat-excited and heat-inhibited neurones in the ventroposterior nucleus of thalamus of anaesthetized rats. Physiological Research / Academia Scientiarum Bohemoslovaca. 46: 53-8. PMID 9728522 | 0.648 | |||
| 1997 | Heinricher MM, McGaraughty S, Grandy DK. Circuitry underlying antiopioid actions of orphanin FQ in the rostral ventromedial medulla. Journal of Neurophysiology. 78: 3351-8. PMID 9405549 DOI: 10.1152/Jn.1997.78.6.3351 | 0.644 | |||
| 1997 | McGaraughty S, Henry JL. Effects of noxious hindpaw immersion on evoked and spontaneous firing of contralateral convergent dorsal horn neurons in both intact and spinalized rats. Brain Research Bulletin. 43: 263-7. PMID 9227835 DOI: 10.1016/S0361-9230(97)00002-6 | 0.601 | |||
| 1997 | McGaraughty S, Henry JL. Relationship between mechano-receptive fields of dorsal horn convergent neurons and the response to noxious immersion of the ipsilateral hindpaw in rats. Pain. 70: 133-40. PMID 9150286 DOI: 10.1016/S0304-3959(97)03328-9 | 0.578 | |||
| 1995 | McGaraughty S, Reinis S, Tsoukatos J. A correlogram analysis of the activity in the rostral ventromedial medulla of awake rats and in rats anesthetized with ketamine or pentobarbital following the administration of morphine. Experimental Brain Research. 106: 283-90. PMID 8566193 DOI: 10.1007/BF00241124 | 0.696 | |||
| 1993 | McGaraughty S, Reinis S, Tsoukatos J. Investigating the role of anaesthetics on the rostral ventromedial medulla: implications for a GABAergic link between ON and OFF cells. Neuroscience Letters. 149: 119-22. PMID 8474681 DOI: 10.1016/0304-3940(93)90750-F | 0.681 | |||
| 1993 | McGaraughty S, Reinis S, Tsoukatos J. Two distinct unit activity responses to morphine in the rostral ventromedial medulla of awake rats. Brain Research. 604: 331-3. PMID 8457860 DOI: 10.1016/0006-8993(93)90385-Z | 0.672 | |||
| 1993 | McGaraughty S, Reinis S. Simultaneous multi- and single-unit recordings in the rostral ventromedial medulla of ketamine-anaesthetized rats, and the cross-correlogram analysis of their interactions. Experimental Brain Research. 92: 489-94. PMID 8454011 DOI: 10.1007/BF00229037 | 0.685 | |||
| 1992 | Reinis S, Weiss DS, McGaraughty S, Tsoukatos J. Method of analysis of local neuronal circuits in the vertebrate central nervous system. Journal of Neuroscience Methods. 43: 1-12. PMID 1528070 DOI: 10.1016/0165-0270(92)90061-H | 0.624 | |||
| 1990 | Reinis S, Weiss DS, McGaraughty S. Analysis of real neuronal circuits in the vertebrate central nervous system Ijcnn. International Joint Conference On Neural Networks. 453-458. | 0.596 | |||
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