Doug Faller - Publications

Affiliations: 
Boston University, Boston, MA, United States 

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Faller DV, Rankin AM. RAS signaling networks Systems Biology of Cancer. 183-192. DOI: 10.1017/9780511979811.013  0.609
2014 Zhu L, Qi J, Chiao CY, Zhang Q, Porco JA, Faller DV, Dai Y. Identification of a novel polyprenylated acylphloroglucinol‑derived SIRT1 inhibitor with cancer‑specific anti-proliferative and invasion-suppressing activities. International Journal of Oncology. 45: 2128-36. PMID 25189993 DOI: 10.3892/Ijo.2014.2639  0.32
2014 Chen Z, Forman LW, Williams RM, Faller DV. Protein kinase C-δ inactivation inhibits the proliferation and survival of cancer stem cells in culture and in vivo. Bmc Cancer. 14: 90. PMID 24528676 DOI: 10.1186/1471-2407-14-90  0.307
2013 Rankin AM, Forman L, Sarkar S, Faller DV. Enhanced cytotoxicity from deoxyguanosine-enriched T-oligo in prostate cancer cells. Nucleic Acid Therapeutics. 23: 311-21. PMID 23971906 DOI: 10.1089/Nat.2013.0420  0.621
2013 Sarkar S, Faller DV. Telomere-homologous G-rich oligonucleotides sensitize human ovarian cancer cells to TRAIL-induced growth inhibition and apoptosis. Nucleic Acid Therapeutics. 23: 167-74. PMID 23634944 DOI: 10.1089/Nat.2012.0401  0.361
2012 Steliou K, Boosalis MS, Perrine SP, Sangerman J, Faller DV. Butyrate histone deacetylase inhibitors. Bioresearch Open Access. 1: 192-8. PMID 23514803 DOI: 10.1089/Biores.2012.0223  0.331
2012 Rankin AM, Sarkar S, Faller DV. Mechanism of T-oligo-induced cell cycle arrest in Mia-PaCa pancreatic cancer cells. Journal of Cellular Physiology. 227: 2586-94. PMID 21898405 DOI: 10.1002/Jcp.22997  0.671
2012 Sorescu GP, Forman LW, Faller DV. Effect of inhibition of protein kinase C delta (PKCδ) on pancreatic cancer cells. Journal of Clinical Oncology. 30: e14591-e14591. DOI: 10.1200/Jco.2012.30.15_Suppl.E14591  0.332
2011 Chen Z, Forman LW, Miller KA, English B, Takashima A, Bohacek RA, Williams RM, Faller DV. Protein kinase Cδ inactivation inhibits cellular proliferation and decreases survival in human neuroendocrine tumors. Endocrine-Related Cancer. 18: 759-71. PMID 21990324 DOI: 10.1530/Erc-10-0224  0.393
2011 Sarkar S, Abujamra AL, Loew JE, Forman LW, Perrine SP, Faller DV. Histone deacetylase inhibitors reverse CpG methylation by regulating DNMT1 through ERK signaling. Anticancer Research. 31: 2723-32. PMID 21868513  0.308
2009 Xia S, Chen Z, Forman LW, Faller DV. PKCdelta survival signaling in cells containing an activated p21Ras protein requires PDK1. Cellular Signalling. 21: 502-8. PMID 19146951 DOI: 10.1016/J.Cellsig.2008.12.002  0.389
2009 Longe HO, Romesser PB, Rankin AM, Faller DV, Eller MS, Gilchrest BA, Denis GV. Telomere homolog oligonucleotides induce apoptosis in malignant but not in normal lymphoid cells: mechanism and therapeutic potential. International Journal of Cancer. Journal International Du Cancer. 124: 473-82. PMID 19003960 DOI: 10.1002/Ijc.23946  0.651
2008 Rankin AM, Faller DV, Spanjaard RA. Telomerase inhibitors and 'T-oligo' as cancer therapeutics: contrasting molecular mechanisms of cytotoxicity. Anti-Cancer Drugs. 19: 329-38. PMID 18454043 DOI: 10.1097/Cad.0B013E3282F5D4C2  0.632
2007 Mork CN, Faller DV, Spanjaard RA. Loss of putative tumor suppressor EI24/PIG8 confers resistance to etoposide. Febs Letters. 581: 5440-4. PMID 17981155 DOI: 10.1016/J.Febslet.2007.10.046  0.727
2007 Xia S, Forman LW, Faller DV. Protein kinase C delta is required for survival of cells expressing activated p21RAS. The Journal of Biological Chemistry. 282: 13199-210. PMID 17350960 DOI: 10.1074/Jbc.M610225200  0.412
2005 Mork CN, Faller DV, Spanjaard RA. A mechanistic approach to anticancer therapy: targeting the cell cycle with histone deacetylase inhibitors. Current Pharmaceutical Design. 11: 1091-104. PMID 15853658 DOI: 10.2174/1381612053507567  0.723
2005 Chen JS, Faller DV. Histone deacetylase inhibition-mediated post-translational elevation of p27KIP1 protein levels is required for G1 arrest in fibroblasts. Journal of Cellular Physiology. 202: 87-99. PMID 15389542 DOI: 10.1002/Jcp.20094  0.348
2004 Liou JS, Chen JS, Faller DV. Characterization of p21Ras-mediated apoptosis induced by protein kinase C inhibition and application to human tumor cell lines. Journal of Cellular Physiology. 198: 277-94. PMID 14603530 DOI: 10.1002/Jcp.10409  0.705
2003 Chen JS, Faller DV, Spanjaard RA. Short-chain fatty acid inhibitors of histone deacetylases: promising anticancer therapeutics? Current Cancer Drug Targets. 3: 219-36. PMID 12769690 DOI: 10.2174/1568009033481994  0.31
2003 Denis GV, Yu Q, Ma P, Deeds L, Faller DV, Chen CY. Bcl-2, via its BH4 domain, blocks apoptotic signaling mediated by mitochondrial Ras. The Journal of Biological Chemistry. 278: 5775-85. PMID 12477721 DOI: 10.1074/Jbc.M210202200  0.314
2002 Ma P, Magut M, Faller DV, Chen CY. The role of Ras in T lymphocyte activation. Cellular Signalling. 14: 849-59. PMID 12135706 DOI: 10.1016/S0898-6568(02)00029-3  0.339
2002 Stice LL, Forman LW, Hahn CS, Faller DV. Desensitization of the PDGFbeta receptor by modulation of the cytoskeleton: the role of p21(Ras) and Rho family GTPases. Experimental Cell Research. 275: 17-30. PMID 11925102 DOI: 10.1006/excr.2002.5482  0.754
2001 Chen CY, Juo P, Liou JS, Li CQ, Yu Q, Blenis J, Faller DV. The recruitment of Fas-associated death domain/caspase-8 in Ras-induced apoptosis. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 12: 297-306. PMID 11432804  0.69
2001 Demary K, Wong L, Liou JS, Faller DV, Spanjaard RA. Redox control of retinoic acid receptor activity: a novel mechanism for retinoic acid resistance in melanoma cells. Endocrinology. 142: 2600-5. PMID 11356710 DOI: 10.1210/Endo.142.6.8201  0.699
2001 Boosalis MS, Bandyopadhyay R, Bresnick EH, Pace BS, Van DeMark K, Zhang B, Faller DV, Perrine SP. Short-chain fatty acid derivatives stimulate cell proliferation and induce STAT-5 activation. Blood. 97: 3259-67. PMID 11342457 DOI: 10.1182/Blood.V97.10.3259  0.339
2001 Lynch EM, Moreland RB, Ginis I, Perrine SP, Faller DV. Hypoxia-activated ligand HAL-1/13 is lupus autoantigen Ku80 and mediates lymphoid cell adhesion in vitro. American Journal of Physiology. Cell Physiology. 280: C897-911. PMID 11245607 DOI: 10.1152/Ajpcell.2001.280.4.C897  0.308
2000 Liou JS, Chen CY, Chen JS, Faller DV. Oncogenic ras mediates apoptosis in response to protein kinase C inhibition through the generation of reactive oxygen species. The Journal of Biological Chemistry. 275: 39001-11. PMID 10967125 DOI: 10.1074/Jbc.M007154200  0.707
2000 Hsing A, Faller DV, Vaziri C. DNA-damaging aryl hydrocarbons induce Mdm2 expression via p53-independent post-transcriptional mechanisms. The Journal of Biological Chemistry. 275: 26024-31. PMID 10856296 DOI: 10.1074/Jbc.M002455200  0.301
2000 Guo N, Faller DV, Vaziri C. A novel DNA damage checkpoint involving post-transcriptional regulation of cyclin A expression. The Journal of Biological Chemistry. 275: 1715-22. PMID 10636867 DOI: 10.1074/Jbc.275.3.1715  0.308
1999 Chen CY, Faller DV. Selective inhibition of protein kinase C isozymes by Fas ligation. The Journal of Biological Chemistry. 274: 15320-8. PMID 10336417 DOI: 10.1074/Jbc.274.22.15320  0.314
1999 Stice LL, Vaziri C, Faller DV. Regulation of platelet-derived growth factor signaling by activated p21Ras. Frontiers in Bioscience : a Journal and Virtual Library. 4: D72-86. PMID 9889183  0.753
1998 Chen CY, Liou J, Forman LW, Faller DV. Correlation of genetic instability and apoptosis in the presence of oncogenic Ki-Ras. Cell Death and Differentiation. 5: 984-95. PMID 9846185 DOI: 10.1038/Sj.Cdd.4400448  0.718
1998 Vaziri C, Stice L, Faller DV. Butyrate-induced G1 arrest results from p21-independent disruption of retinoblastoma protein-mediated signals. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 9: 465-74. PMID 9663465  0.75
1998 Chen CY, Liou J, Forman LW, Faller DV. Differential regulation of discrete apoptotic pathways by Ras. The Journal of Biological Chemistry. 273: 16700-9. PMID 9642224 DOI: 10.1074/Jbc.273.27.16700  0.717
1997 Vaziri C, Faller DV. A benzo[a]pyrene-induced cell cycle checkpoint resulting in p53-independent G1 arrest in 3T3 fibroblasts. The Journal of Biological Chemistry. 272: 2762-9. PMID 9006915 DOI: 10.1074/Jbc.272.5.2762  0.307
1996 Chen CY, Forman LW, Faller DV. Calcium-dependent immediate-early gene induction in lymphocytes is negatively regulated by p21Ha-ras. Molecular and Cellular Biology. 16: 6582-92. PMID 8887687 DOI: 10.1128/Mcb.16.11.6582  0.361
1996 Vaziri C, Schneider A, Sherr DH, Faller DV. Expression of the aryl hydrocarbon receptor is regulated by serum and mitogenic growth factors in murine 3T3 fibroblasts. The Journal of Biological Chemistry. 271: 25921-7. PMID 8824226 DOI: 10.1074/Jbc.271.42.25921  0.334
1996 Vaziri C, Faller DV. Down-regulation of platelet-derived growth factor receptor expression during terminal differentiation of 3T3-L1 pre-adipocyte fibroblasts. The Journal of Biological Chemistry. 271: 13642-8. PMID 8662875 DOI: 10.1074/Jbc.271.23.13642  0.314
1996 Zubiaur M, Forman LW, Stice LL, Faller DV. A role for activated p21 ras in inhibition/regulation of platelet-derived growth factor (PDGF) type-beta receptor activation. Oncogene. 12: 1213-22. PMID 8649823  0.744
1996 Pak J, Faller DV. Moloney murine leukemia virus activates NF-kappa B. Journal of Virology. 70: 4167-72. PMID 8648762  0.571
1996 Chen CY, Faller DV. Phosphorylation of Bcl-2 protein and association with p21Ras in Ras-induced apoptosis. The Journal of Biological Chemistry. 271: 2376-9. PMID 8576193 DOI: 10.1074/Jbc.271.5.2376  0.356
1995 Mundschau LJ, Faller DV. Platelet-derived growth factor signal transduction through the interferon-inducible kinase PKR. Immediate early gene induction. The Journal of Biological Chemistry. 270: 3100-6. PMID 7531699 DOI: 10.1074/Jbc.270.7.3100  0.334
1995 Chen CY, Faller DV. Direction of p21ras-generated signals towards cell growth or apoptosis is determined by protein kinase C and Bcl-2. Oncogene. 11: 1487-98. PMID 7478573  0.41
1995 Lichtman AH, Lee L, Faller DV. Stepwise progression of growth factor autonomy in murine T cell expressing activated ras genes 1 Cancer Molecular Biology. 2: 427-440.  0.337
1994 Mundschau LJ, Forman LW, Weng H, Faller DV. Platelet-derived growth factor (PDGF) induction of egr-1 is independent of PDGF receptor autophosphorylation on tyrosine. The Journal of Biological Chemistry. 269: 16137-42. PMID 8206913  0.304
1994 Mundschau LJ, Faller DV. Endogenous inhibitors of the dsRNA-dependent eIF-2 alpha protein kinase PKR in normal and ras-transformed cells. Biochimie. 76: 792-800. PMID 7893828 DOI: 10.1016/0300-9084(94)90083-3  0.357
1992 Kwok RP, Cameron JL, Faller DV, Fernstrom JD. Effects of cysteamine administration on somatostatin biosynthesis and levels in rat hypothalamus. Endocrinology. 131: 2999-3009. PMID 1359964 DOI: 10.1210/Endo.131.6.1359964  0.44
1992 Mundschau LJ, Faller DV. Oncogenic ras induces an inhibitor of double-stranded RNA-dependent eukaryotic initiation factor 2 alpha-kinase activation. The Journal of Biological Chemistry. 267: 23092-8. PMID 1358881  0.347
1991 Rake JB, Quiñones MA, Faller DV. Inhibition of platelet-derived growth factor-mediated signal transduction by transforming ras. Suppression of receptor autophosphorylation. The Journal of Biological Chemistry. 266: 5348-52. PMID 1848245  0.331
1991 Quiñones MA, Mundschau LJ, Rake JB, Faller DV. Dissociation of platelet-derived growth factor (PDGF) receptor autophosphorylation from other PDGF-mediated second messenger events. The Journal of Biological Chemistry. 266: 14055-63. PMID 1713214  0.303
1978 Fernstrom JD, Faller DV. Neutral amino acids in the brain: changes in response to food ingestion. Journal of Neurochemistry. 30: 1531-8. PMID 670995  0.417
1976 Fernstrom JD, Hirsch MJ, Faller DV. Tryptophan concentrations in rat brain. Failure to correlate with free serum tryptophan or its ratio to the sum of other serum neutral amino acids. The Biochemical Journal. 160: 589-95. PMID 1016241  0.429
1975 Fernstrom JD, Faller DV, Shabshelowitz H. Acute reduction of brain serotonin and 5-HIAA following food consumption: correlation with the ratio of serum tryptophan to the sum of competing amino acids. Journal of Neural Transmission. 36: 113-21. PMID 1080186 DOI: 10.1007/BF01256759  0.43
1974 Fernstrom JD, Shabshelowitz H, Faller DV. Diazepam increases 5-hydroxyindole concentrations in rat brain and spinal cord. Life Sciences. 15: 1577-84. PMID 4549994 DOI: 10.1016/0024-3205(74)90323-3  0.405
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