cached image

Damian Winston Young, Ph.D. - Publications

Affiliations: 
2004 North Carolina State University, Raleigh, NC 
 2005-2009 Chemical Biology Harvard University, Cambridge, MA, United States 
 2011- Pathology, Chemical Biology Baylor College of Medicine, Houston, TX 
Area:
Organic Chemistry
Website:
https://www.bcm.edu/people/view/damian-young-ph-d/02c710f0-40e7-11e3-9de7-005056b104be

15/228 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Wang Y, Wach JY, Sheehan P, Zhong C, Zhan C, Harris R, Almo SC, Bishop J, Haggarty SJ, Ramek A, Berry KN, O'Herin C, Koehler AN, Hung AW, Young DW. Diversity-Oriented Synthesis as a Strategy for Fragment Evolution against GSK3β. Acs Medicinal Chemistry Letters. 7: 852-6. PMID 27660690 DOI: 10.1021/Acsmedchemlett.6B00230  0.704
2013 Yuan Y, Hartland K, Boskovic Z, Wang Y, Walpita D, Lysy PA, Zhong C, Young DW, Kim YK, Tolliday NJ, Sokal EM, Schreiber SL, Wagner BK. A small-molecule inducer of PDX1 expression identified by high-throughput screening. Chemistry & Biology. 20: 1513-22. PMID 24290880 DOI: 10.1016/J.Chembiol.2013.10.013  0.628
2013 Wang Y, Jimenez M, Sheehan P, Zhong C, Hung AW, Tam CP, Young DW. Selective access to trisubstituted macrocyclic E- and Z-alkenes from the ring-closing metathesis of vinylsiloxanes. Organic Letters. 15: 1218-21. PMID 23448432 DOI: 10.1021/Ol400134D  0.59
2013 Zhong C, Wang Y, O'Herin C, Young DW. Synthesis of substituted morpholines using stereodivergent aza-michael reactions catalyzed by Brønsted acids Acs Catalysis. 3: 643-646. DOI: 10.1021/Cs400031P  0.596
2013 Comins DL, Higuchi K, Young DW. Dihydropyridine preparation and application in the synthesis of pyridine derivatives Advances in Heterocyclic Chemistry. 110: 175-235. DOI: 10.1016/B978-0-12-408100-0.00006-9  0.513
2011 Zhong C, Wang Y, Hung AW, Schreiber SL, Young DW. Diastereoselective control of intramolecular aza-Michael reactions using achiral catalysts. Organic Letters. 13: 5556-9. PMID 21916463 DOI: 10.1021/Ol202276H  0.638
2011 Pandya BA, Dandapani S, Duvall JR, Rowley A, Mulrooney CA, Ryba T, Dombrowski M, Harton M, Young DW, Marcaurelle LA. Practical asymmetric synthesis of β-hydroxy γ-amino acids via complimentary aldol reactions. Tetrahedron. 67: 6131-6137. PMID 21822337 DOI: 10.1016/J.Tet.2011.06.043  0.341
2011 Wang Y, Jimenez M, Hansen AS, Raiber EA, Schreiber SL, Young DW. Control of olefin geometry in macrocyclic ring-closing metathesis using a removable silyl group. Journal of the American Chemical Society. 133: 9196-9. PMID 21557625 DOI: 10.1021/Ja202012S  0.638
2011 Hung AW, Ramek A, Wang Y, Kaya T, Wilson JA, Clemons PA, Young DW. Route to three-dimensional fragments using diversity-oriented synthesis. Proceedings of the National Academy of Sciences of the United States of America. 108: 6799-804. PMID 21482811 DOI: 10.1073/Pnas.1015271108  0.687
2010 Marcaurelle LA, Comer E, Dandapani S, Duvall JR, Gerard B, Kesavan S, Lee MD, Liu H, Lowe JT, Marie JC, Mulrooney CA, Pandya BA, Rowley A, Ryba TD, Suh BC, ... ... Young DW, et al. An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors. Journal of the American Chemical Society. 132: 16962-76. PMID 21067169 DOI: 10.1021/Ja105119R  0.603
2010 Dancík V, Seiler KP, Young DW, Schreiber SL, Clemons PA. Distinct biological network properties between the targets of natural products and disease genes. Journal of the American Chemical Society. 132: 9259-61. PMID 20565092 DOI: 10.1021/Ja102798T  0.6
2010 Young DW. Synthetic chemistry: An upfront investment. Nature Chemical Biology. 6: 174-175. PMID 20154664 DOI: 10.1038/Nchembio.325  0.341
2009 Kelly AR, Wei J, Kesavan S, Marié JC, Windmon N, Young DW, Marcaurelle LA. Accessing skeletal diversity using catalyst control: formation of n and n + 1 macrocyclic triazole rings. Organic Letters. 11: 2257-60. PMID 19473044 DOI: 10.1021/Ol900562U  0.321
2007 Bender A, Young DW, Jenkins JL, Serrano M, Mikhailov D, Clemons PA, Davies JW. Chemogenomic data analysis: prediction of small-molecule targets and the advent of biological fingerprint. Combinatorial Chemistry & High Throughput Screening. 10: 719-31. PMID 18045083 DOI: 10.2174/138620707782507313  0.556
2005 Young DW, Comins DL. Tandem directed lithiations of N-Boc-1,2-dihydropyridines toward highly functionalized 2,3-dihydro-4-pyridones. Organic Letters. 7: 5661-4. PMID 16321016 DOI: 10.1021/Ol052313A  0.538
Low-probability matches (unlikely to be authored by this person)
2018 Guduru SKR, Chamakuri S, Raji IO, MacKenzie KR, Santini C, Young DW. Synthesis of Enantiomerically Pure 3-Substituted-Piperazine-2-Acetic Acid Esters as Intermediates for Library Production. The Journal of Organic Chemistry. PMID 30180575 DOI: 10.1021/Acs.Joc.8B01708  0.287
2018 Chamakuri S, Jain P, Guduru SKR, Arney JW, MacKenzie K, Santini C, Young DW. Synthesis of Enantiomerically Pure 6-Substituted-Piperazine-2-Acetic Acid Esters as Intermediates for Library Production. The Journal of Organic Chemistry. PMID 29751727 DOI: 10.1021/Acs.Joc.8B00854  0.279
2019 Jain P, Raji IO, Chamakuri S, MacKenzie KR, Ebright BT, Santini C, Young DW. Synthesis of Enantiomerically Pure 5-Substituted-Piperazine-2-Acetic Acid Esters as Intermediates for Library Production. The Journal of Organic Chemistry. PMID 30848904 DOI: 10.1021/Acs.Joc.9B00148  0.271
1980 Young D. Advances in Heterocyclic Chemistry Journal of Organometallic Chemistry. 338: C14. DOI: 10.1016/0022-328X(80)83018-X  0.27
2004 Young D. Journal of Organometallic Chemistry. 689: 4921. DOI: 10.1016/J.Jorganchem.2004.06.036  0.264
1973 Storer R, Young DW, Taylor DR, Warner JM. Isolation and synthesis of N-methyl-4,7,8-trimethoxy-2-quinolone from Spathelia sorbifolia L Tetrahedron. 29: 1721-1723. DOI: 10.1016/0040-4020(73)80118-8  0.264
2023 Viveki A, Mansfield T, Tran K, Lenkeit E, MacKenzie K, Young DW, Chamakuri S. Heterocyclic Merging of Stereochemically Diverse Chiral Piperazines and Morpholines with Indazoles. Chemistry (Weinheim An Der Bergstrasse, Germany). e202301888. PMID 37462979 DOI: 10.1002/chem.202301888  0.246
2001 Charrier JD, Duffy JES, Hitchcock PB, Young DW. Unusual stereoselectivity in the alkylation of pyroglutamate ester urethanes Journal of the Chemical Society. Perkin Transactions 1. 2367-2371. DOI: 10.1039/B106451G  0.242
2005 Berry JM, Doyle PM, Young DW. Synthesis of external β-turn templates by reaction of protected dehydroamino acids with cyclic enaminoesters Tetrahedron. 61: 287-299. DOI: 10.1016/J.Tet.2004.09.036  0.237
1986 Avent AG, Chaloner PA, Leonard KA, Young DW. Dynamic behaviour of 2,2-dimethyl-3-formyl-4-carbonyl- 4-thiazolinyl valine esters Tetrahedron. 42: 4343-4346. DOI: 10.1016/S0040-4020(01)87661-4  0.236
1973 Storer R, Young D. Constituents of the root of Dictamnus albus L. Tetrahedron. 29: 1217-1222. DOI: 10.1016/0040-4020(73)80105-X  0.23
2008 Young DW, Bender A, Hoyt J, McWhinnie E, Chirn GW, Tao CY, Tallarico JA, Labow M, Jenkins JL, Mitchison TJ, Feng Y. Integrating high-content screening and ligand-target prediction to identify mechanism of action. Nature Chemical Biology. 4: 59-68. PMID 18066055 DOI: 10.1038/Nchembio.2007.53  0.23
1973 Storer R, Young D. Synthesis of halfordamine, an alkaloid from Halfordia kendack Tetrahedron. 29: 1215-1216. DOI: 10.1016/0040-4020(73)80104-8  0.228
2020 Monty OBC, Nyshadham P, Bohren K, Palaniappan M, Matzuk MM, Young DW, Simmons N. Homogeneous and Functional Group Tolerant Ring-Closing Metathesis for DNA-Encoded Chemical Libraries. Acs Combinatorial Science. PMID 31913011 DOI: 10.1021/acscombsci.9b00199  0.228
2019 Chamakuri S, Jain P, Guduru SRK, Arney JW, MacKenzie KR, Santini C, Young DW. Correction to Synthesis of Enantiomerically Pure 6-Substituted-Piperazine-2-Acetic Acid Esters as Intermediates for Library Production. The Journal of Organic Chemistry. PMID 30855144 DOI: 10.1021/Acs.Joc.9B00594  0.228
2000 Burtin G, Corringer PJ, Young DW. Tetrahydro-1,3-oxazin-6-ones as templates for the stereoselective synthesis of β-substituted L-aspartic acids Journal of the Chemical Society, Perkin Transactions 1. 3451-3459. DOI: 10.1039/B004772O  0.225
2020 Chamakuri S, Shah MM, Yang DCH, Santini C, Young DW. Practical and scalable synthesis of orthogonally protected-2-substituted chiral piperazines. Organic & Biomolecular Chemistry. PMID 33118584 DOI: 10.1039/d0ob01713b  0.223
2000 Dinsmore A, Doyle PM, Hitchcock PB, Young DW. Extension of ring switching strategy to the glutamate antagonist 2-(pyrimidin-2,4-dione-5-ylmethyl)-(2S)-glycine and related compounds with two chiral centres Tetrahedron Letters. 41: 10153-10158. DOI: 10.1016/S0040-4039(00)01800-1  0.223
2014 Baker SJ, Beresford KJM, Young DW. Synthesis of homochiral tetrahydropteridines Tetrahedron. DOI: 10.1016/J.Tet.2014.06.048  0.221
2021 Chamakuri S, Chung MK, Samuel ELG, Tran KA, Chen YC, Nyshadham P, Santini C, Matzuk MM, Young DW. Design and construction of a stereochemically diverse piperazine-based DNA-encoded chemical library. Bioorganic & Medicinal Chemistry. 48: 116387. PMID 34571488 DOI: 10.1016/j.bmc.2021.116387  0.218
2006 Ahmed O, Hitchcock PB, Young DW. Investigation of a route to ibotenic acid analogues via a reduced pyroglutamate template. Organic & Biomolecular Chemistry. 4: 1596-603. PMID 16604229 DOI: 10.1039/B600195E  0.216
2020 Monty OBC, Simmons N, Chamakuri S, Matzuk MM, Young DW. Solution-Phase Fmoc-Based Peptide Synthesis for DNA-Encoded Chemical Libraries: Reaction Conditions, Protecting Group Strategies, and Pitfalls. Acs Combinatorial Science. PMID 33074645 DOI: 10.1021/acscombsci.0c00144  0.213
2021 Chang L, Campbell J, Raji IO, Guduru SKR, Kandel P, Nguyen M, Liu S, Tran K, Venugopal NK, Taylor BC, Holt MV, Young NL, Samuel ELG, Jain P, Santini C, ... ... Young DW, et al. Discovery of small molecules targeting the tandem tudor domain of the epigenetic factor UHRF1 using fragment-based ligand discovery. Scientific Reports. 11: 1121. PMID 33441849 DOI: 10.1038/s41598-020-80588-4  0.211
2005 Moody CM, Young DW. Investigation into direct use of protected 3,4-dehydropyroglutamates in synthesis Journal of Chemical Research. 478-480. DOI: 10.3184/030823405774309087  0.207
2002 Dinsmore A, Doyle PM, Young DW. Use of a modified ring-switching strategy to synthesise the glutamate antagonist (2s)-2-amino-3-(2,4- oxo-1,2,3,4-tetra-hydropyrimidin-5-yl)propionate and related compounds with two chiral centres Journal of the Chemical Society. Perkin Transactions 1. 2: 155-164. DOI: 10.1039/B109820A  0.207
2022 Chamakuri S, Tang SA, Tran KA, Guduru SKR, Bolin PK, MacKenzie KR, Young DW. A Concise Synthetic Method for Constructing 3-Substituted Piperazine-2-Acetic Acid Esters from 1,2-Diamines. Molecules (Basel, Switzerland). 27. PMID 35684357 DOI: 10.3390/molecules27113419  0.206
2019 Boyd SR, Young DW. Max-imizing the Attenuation of Myc Using Small Molecules. Trends in Pharmacological Sciences. PMID 31280901 DOI: 10.1016/j.tips.2019.06.002  0.205
2001 Young D. Protecting Groups, Edited by P.J. Kocienski, Georg Thieme Verlag, Stuttgart, 2000, pp. xv+260, ISBN 3-13-137002-5; DM 99, SFr 90, Euro 50.62 Journal of Organometallic Chemistry. 619: 320. DOI: 10.1016/S0022-328X(00)00645-8  0.203
2001 Hitchcock PB, Starkmann BA, Young DW. Double stereodifferentiation in aldol reactions on protected pyroglutamate esters Tetrahedron Letters. 42: 2381-2384. DOI: 10.1016/S0040-4039(01)00150-2  0.203
2024 Holmes S, Jain P, Rodriguez KG, Williams J, Yu Z, Cerda-Smith C, Samuel ELG, Campbell J, Hakenjos JM, Monsivais D, Li F, Chamakuri S, Matzuk MM, Santini C, MacKenzie KR, ... Young DW, et al. Chemical Catalysis Guides Structural Identification for the Major Metabolite of the BET Inhibitor JQ1. Acs Medicinal Chemistry Letters. 15: 107-115. PMID 38229743 DOI: 10.1021/acsmedchemlett.3c00464  0.201
2021 Yu Z, Ku AF, Anglin JL, Sharma R, Ucisik MN, Faver JC, Li F, Nyshadham P, Simmons N, Sharma KL, Nagarajan S, Riehle K, Kaur G, Sankaran B, Storl-Desmond M, ... ... Young DW, et al. Discovery and characterization of bromodomain 2-specific inhibitors of BRDT. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33637650 DOI: 10.1073/pnas.2021102118  0.198
2009 Feng Y, Mitchison TJ, Bender A, Young DW, Tallarico JA. Multi-parameter phenotypic profiling: using cellular effects to characterize small-molecule compounds. Nature Reviews. Drug Discovery. 8: 567-78. PMID 19568283 DOI: 10.1038/Nrd2876  0.195
2022 Young DW, Chamakuri S. Trisubstituted triumph. Nature Chemistry. 14: 595-597. PMID 35668207 DOI: 10.1038/s41557-022-00959-4  0.193
1999 Steger M, Young DW. Versatile synthesis of inhibitors of late enzymes in the bacterial pathway to lysine Tetrahedron. 55: 7935-7956. DOI: 10.1016/S0040-4020(99)00403-2  0.192
2021 Chamakuri S, Lu S, Ucisik MN, Bohren KM, Chen YC, Du HC, Faver JC, Jimmidi R, Li F, Li JY, Nyshadham P, Palmer SS, Pollet J, Qin X, Ronca SE, ... ... Young DW, et al. DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 M inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34426525 DOI: 10.1073/pnas.2111172118  0.189
2005 Zaidi SK, Young DW, Choi JY, Pratap J, Javed A, Montecino M, Stein JL, van Wijnen AJ, Lian JB, Stein GS. The dynamic organization of gene-regulatory machinery in nuclear microenvironments. Embo Reports. 6: 128-33. PMID 15689940 DOI: 10.1038/Sj.Embor.7400337  0.189
2002 Berry JM, Doyle PM, Young DW. An interesting dichotomy in the cyclisation of exocyclic enamines with protected dehydroamino acids leading to different β-turn templates Tetrahedron Letters. 43: 8963-8966. DOI: 10.1016/S0040-4039(02)02141-X  0.187
2002 Starkmann BA, Young DW. Double stereodifferentiation in aldol reactions of pyroglutamic urethane esters Journal of the Chemical Society. Perkin Transactions 1. 725-732. DOI: 10.1039/B200443G  0.185
2022 Modukuri RK, Yu Z, Tan Z, Ta HM, Ucisik MN, Jin Z, Anglin JL, Sharma KL, Nyshadham P, Li F, Riehle K, Faver JC, Duong K, Nagarajan S, Simmons N, ... ... Young DW, et al. Discovery of potent BET bromodomain 1 stereoselective inhibitors using DNA-encoded chemical library selections. Proceedings of the National Academy of Sciences of the United States of America. 119: e2122506119. PMID 35622893 DOI: 10.1073/pnas.2122506119  0.184
2007 Young DW, Hassan MQ, Yang XQ, Galindo M, Javed A, Zaidi SK, Furcinitti P, Lapointe D, Montecino M, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2. Proceedings of the National Academy of Sciences of the United States of America. 104: 3189-94. PMID 17360627 DOI: 10.1073/Pnas.0611419104  0.184
2010 Stein GS, Stein JL, Van Wijnen AJ, Lian JB, Montecino M, Croce CM, Choi JY, Ali SA, Pande S, Hassan MQ, Zaidi SK, Young DW. Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer. Advances in Enzyme Regulation. 50: 160-7. PMID 19896493 DOI: 10.1016/J.Advenzreg.2009.10.026  0.182
2002 Papadopoulos K, Young DW. Versatile synthesis of ibotenic acid analogues with potential for activity at glutamate receptors by use of a homochiral β-lactam template in our 'ring switching' strategy Tetrahedron Letters. 43: 3951-3955. DOI: 10.1016/S0040-4039(02)00590-7  0.178
2003 Hitchcock PB, Papadopoulos K, Young DW. Beta-lactams as versatile synthons for homochiral ibotenate analogues with potential for activity at glutamate receptors. Organic & Biomolecular Chemistry. 1: 2670-81. PMID 12948191 DOI: 10.1039/B304607A  0.173
2005 Davies DE, Doyle PM, Hill RD, Young DW. Synthesis of an external beta-turn based on the GLDV motif of cell adhesion proteins Tetrahedron. 61: 301-312. DOI: 10.1016/J.Tet.2004.09.037  0.172
2003 Balint E, Lapointe D, Drissi H, van der Meijden C, Young DW, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Phenotype discovery by gene expression profiling: mapping of biological processes linked to BMP-2-mediated osteoblast differentiation. Journal of Cellular Biochemistry. 89: 401-26. PMID 12704803 DOI: 10.1002/Jcb.10515  0.17
2004 Zaidi SK, Young DW, Choi JY, Pratap J, Javed A, Montecino M, Stein JL, Lian JB, van Wijnen AJ, Stein GS. Intranuclear trafficking: organization and assembly of regulatory machinery for combinatorial biological control. The Journal of Biological Chemistry. 279: 43363-6. PMID 15277516 DOI: 10.1074/Jbc.R400020200  0.17
2005 Young DW, Pratap J, Javed A, Weiner B, Ohkawa Y, van Wijnen A, Montecino M, Stein GS, Stein JL, Imbalzano AN, Lian JB. SWI/SNF chromatin remodeling complex is obligatory for BMP2-induced, Runx2-dependent skeletal gene expression that controls osteoblast differentiation. Journal of Cellular Biochemistry. 94: 720-30. PMID 15565649 DOI: 10.1002/Jcb.20332  0.168
2000 Capps NK, Davies GM, Loakes D, Young DW. Synthesis of tricyclic β-lactams related to cephalosporins Journal of the Chemical Society, Perkin Transactions 1. 4373-4381. DOI: 10.1039/B006415G  0.167
2022 Sarrion-Perdigones A, Gonzalez Y, Chang L, Gallego-Flores T, Young DW, Venken KJT. Multiplex Hextuple Luciferase Assaying. Methods in Molecular Biology (Clifton, N.J.). 2524: 433-456. PMID 35821491 DOI: 10.1007/978-1-0716-2453-1_33  0.165
2008 Ali SA, Zaidi SK, Dacwag CS, Salma N, Young DW, Shakoori AR, Montecino MA, Lian JB, van Wijnen AJ, Imbalzano AN, Stein GS, Stein JL. Phenotypic transcription factors epigenetically mediate cell growth control. Proceedings of the National Academy of Sciences of the United States of America. 105: 6632-7. PMID 18445650 DOI: 10.1073/Pnas.0800970105  0.164
2005 Saltman LH, Javed A, Ribadeneyra J, Hussain S, Young DW, Osdoby P, Amcheslavsky A, van Wijnen AJ, Stein JL, Stein GS, Lian JB, Bar-Shavit Z. Organization of transcriptional regulatory machinery in osteoclast nuclei: compartmentalization of Runx1. Journal of Cellular Physiology. 204: 871-80. PMID 15828028 DOI: 10.1002/Jcp.20329  0.163
2012 van der Deen M, Akech J, Lapointe D, Gupta S, Young DW, Montecino MA, Galindo M, Lian JB, Stein JL, Stein GS, van Wijnen AJ. Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility. The Journal of Biological Chemistry. 287: 4503-17. PMID 22158627 DOI: 10.1074/Jbc.M111.287771  0.163
1999 Bhattia SH, Davics GM, Hitchcock PB, Loakes D, Young DW. Synthesis of reactive y-Iactams related to penicillins and cephalosporins Journal of the Chemical Society - Perkin Transactions 1. 2449-2454.  0.162
2023 Jimmidi R, Chamakuri S, Lu S, Ucisik MN, Chen PJ, Bohren KM, Moghadasi SA, Versteeg L, Nnabuife C, Li JY, Qin X, Chen YC, Faver JC, Nyshadham P, Sharma KL, ... ... Young DW, et al. DNA-encoded chemical libraries yield non-covalent and non-peptidic SARS-CoV-2 main protease inhibitors. Communications Chemistry. 6: 164. PMID 37542196 DOI: 10.1038/s42004-023-00961-y  0.162
2002 Dinsmore A, Doyle PM, Steger M, Young DW. Synthesis of homochiral amino acid pyrazine and pyrrole analogues of glutamate antagonists Journal of the Chemical Society. Perkin Transactions 1. 613-621. DOI: 10.1039/B110979K  0.162
2019 Sarrion-Perdigones A, Chang L, Gonzalez Y, Gallego-Flores T, Young DW, Venken KJT. Examining multiple cellular pathways at once using multiplex hextuple luciferase assaying. Nature Communications. 10: 5710. PMID 31836712 DOI: 10.1038/s41467-019-13651-y  0.159
1999 Burtin G, Corringer PJ, Hitchcock PB, Young DW. Stereoselective synthesis of β-substituted aspartic acids via tetrahydro-1,3-oxazin-6-ones Tetrahedron Letters. 40: 4275-4278. DOI: 10.1016/S0040-4039(99)00705-4  0.159
2006 Beresford KJ, Church NJ, Young DW. Synthesis of alpha-amino acids by reaction of aziridine-2-carboxylic acids with carbon nucleophiles. Organic & Biomolecular Chemistry. 4: 2888-97. PMID 16855737 DOI: 10.1039/B605026N  0.158
2009 Stein GS, Zaidi SK, Stein JL, Lian JB, van Wijnen AJ, Montecino M, Young DW, Javed A, Pratap J, Choi JY, Ali SA, Pande S, Hassan MQ. Transcription-factor-mediated epigenetic control of cell fate and lineage commitment. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 87: 1-6. PMID 19234518 DOI: 10.1139/O08-094  0.157
2004 Stein GS, Lian JB, van Wijnen AJ, Stein JL, Montecino M, Javed A, Zaidi SK, Young DW, Choi JY, Pockwinse SM. Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression. Oncogene. 23: 4315-29. PMID 15156188 DOI: 10.1038/Sj.Onc.1207676  0.156
2022 Ye Q, Belabed H, Wang Y, Yu Z, Palaniappan M, Li JY, Kalovidouris SA, MacKenzie KR, Teng M, Young DW, Fujihara Y, Matzuk MM. Advancing ASMS with LC-MS/MS for the discovery of novel PDCL2 ligands from DNA-Encoded chemical library selections. Andrology. PMID 36209044 DOI: 10.1111/andr.13309  0.154
2005 Stein GS, Lian JB, Stein JL, van Wijnen AJ, Javed A, Montecino M, Zaidi SK, Young DW, Choi JY, Pratap J. Combinatorial organization of the transcriptional regulatory machinery in biological control and cancer. Advances in Enzyme Regulation. 45: 136-54. PMID 16135382 DOI: 10.1016/J.Advenzreg.2005.02.009  0.153
2007 Young DW, Hassan MQ, Pratap J, Galindo M, Zaidi SK, Lee SH, Yang X, Xie R, Javed A, Underwood JM, Furcinitti P, Imbalzano AN, Penman S, Nickerson JA, Montecino MA, et al. Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2. Nature. 445: 442-6. PMID 17251981 DOI: 10.1038/Nature05473  0.152
2020 Sarrion-Perdigones A, Chang L, Gonzalez Y, Gallego-Flores T, Young DW, Venken KJT. Simultaneous Examination of Cellular Pathways using Multiplex Hextuple Luciferase Assaying. Current Protocols in Molecular Biology. 131: e122. PMID 32539239 DOI: 10.1002/cpmb.122  0.15
2010 Zaidi SK, Young DW, Montecino M, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information. Molecular and Cellular Biology. 30: 4758-66. PMID 20696837 DOI: 10.1128/Mcb.00646-10  0.148
2022 Moghadasi SA, Esler MA, Otsuka Y, Becker JT, Moraes SN, Anderson CB, Chamakuri S, Belica C, Wick C, Harki DA, Young DW, Scampavia L, Spicer TP, Shi K, Aihara H, et al. Gain-of-Signal Assays for Probing Inhibition of SARS-CoV-2 M/3CL in Living Cells. Mbio. e0078422. PMID 35471084 DOI: 10.1128/mbio.00784-22  0.147
2002 Hawkins LD, Ishizaka ST, McGuinness P, Zhang H, Gavin W, DeCosta B, Meng Z, Yang H, Mullarkey M, Young DW, Yang H, Rossignol DP, Nault A, Rose J, Przetak M, et al. A novel class of endotoxin receptor agonists with simplified structure, toll-like receptor 4-dependent immunostimulatory action, and adjuvant activity. The Journal of Pharmacology and Experimental Therapeutics. 300: 655-61. PMID 11805229 DOI: 10.1124/jpet.300.2.655  0.146
2006 Lian JB, Stein GS, Javed A, van Wijnen AJ, Stein JL, Montecino M, Hassan MQ, Gaur T, Lengner CJ, Young DW. Networks and hubs for the transcriptional control of osteoblastogenesis. Reviews in Endocrine & Metabolic Disorders. 7: 1-16. PMID 17051438 DOI: 10.1007/S11154-006-9001-5  0.145
2011 Zaidi SK, Young DW, Montecino M, van Wijnen AJ, Stein JL, Lian JB, Stein GS. Bookmarking the genome: maintenance of epigenetic information. The Journal of Biological Chemistry. 286: 18355-61. PMID 21454629 DOI: 10.1074/Jbc.R110.197061  0.145
2004 Charrier JD, Hadfield DS, Hitchcock PB, Young DW. Synthesis of (2S,3S)-3'-fluoroisoleucine. Organic & Biomolecular Chemistry. 2: 797-802. PMID 14985821 DOI: 10.1039/B316219B  0.144
2005 Avent AG, Duggan HM, Young DW. Synthesis of protected gamma-carboxyglutamates and gamma-acylglutamates by rearrangement of N,N-diacylglutamates. Organic & Biomolecular Chemistry. 3: 2327-32. PMID 16010368 DOI: 10.1039/B503900B  0.144
2003 Zaidi SK, Young DW, Pockwinse SM, Javed A, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Mitotic partitioning and selective reorganization of tissue-specific transcription factors in progeny cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 14852-7. PMID 14657346 DOI: 10.1073/Pnas.2533076100  0.144
2021 Samuel ELG, Holmes SL, Young DW. Processing binding data using an open-source workflow. Journal of Cheminformatics. 13: 99. PMID 34895330 DOI: 10.1186/s13321-021-00577-1  0.142
2003 Davies DE, Doyle PM, Farrant RD, Hill RD, Hitchcock PB, Sanderson PN, Young DW. Synthesis of an external β-turn based on the GLDV motif of cell adhesion proteins Tetrahedron Letters. 44: 8887-8891. DOI: 10.1016/j.tetlet.2003.09.170  0.141
2008 Bakshi R, Zaidi SK, Pande S, Hassan MQ, Young DW, Montecino M, Lian JB, van Wijnen AJ, Stein JL, Stein GS. The leukemogenic t(8;21) fusion protein AML1-ETO controls rRNA genes and associates with nucleolar-organizing regions at mitotic chromosomes. Journal of Cell Science. 121: 3981-90. PMID 19001502 DOI: 10.1242/Jcs.033431  0.14
2023 Modukuri RK, Monsivais D, Li F, Palaniappan M, Bohren KM, Tan Z, Ku AF, Wang Y, Madasu C, Li JY, Tang S, Miklossy G, Palmer SS, Young DW, Matzuk MM. Discovery of Highly Potent and BMPR2-Selective Kinase Inhibitors Using DNA-Encoded Chemical Library Screening. Journal of Medicinal Chemistry. PMID 36719862 DOI: 10.1021/acs.jmedchem.2c01886  0.14
2000 Adams B, Axelsson BS, Beresford KJM, Church NJ, Spencer PA, Whyte SM, Young DW. Use of inhibitors to study reactions catalyzed by enzymes requiring pyridoxal phosphate as coenzyme Pure and Applied Chemistry. 72: 373-384. DOI: 10.1351/Pac200072030373  0.14
2008 Teplyuk NM, Galindo M, Teplyuk VI, Pratap J, Young DW, Lapointe D, Javed A, Stein JL, Lian JB, Stein GS, van Wijnen AJ. Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors. The Journal of Biological Chemistry. 283: 27585-97. PMID 18625716 DOI: 10.1074/Jbc.M802453200  0.139
2010 Zaidi SK, Medina RF, Pockwinse SM, Bakshi R, Kota KP, Ali SA, Young DW, Nickerson JA, Javed A, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. Subnuclear localization and intranuclear trafficking of transcription factors. Methods in Molecular Biology (Clifton, N.J.). 647: 77-93. PMID 20694661 DOI: 10.1007/978-1-60761-738-9_4  0.138
2020 Li F, MacKenzie KR, Jain P, Santini C, Young DW, Matzuk MM. Metabolism of JQ1, an inhibitor of BET bromodomain proteins, in human and mouse liver microsomes†. Biology of Reproduction. PMID 32285106 DOI: 10.1093/biolre/ioaa043  0.138
1999 Davies GM, McCabe RW, Young DW. Ring contraction of dihydro[1,3]thiazines to pyrroles on cyclisation Journal of the Chemical Society - Perkin Transactions 1. 3565-3567.  0.137
2004 Young DW, Zaidi SK, Furcinitti PS, Javed A, van Wijnen AJ, Stein JL, Lian JB, Stein GS. Quantitative signature for architectural organization of regulatory factors using intranuclear informatics. Journal of Cell Science. 117: 4889-96. PMID 15367579 DOI: 10.1242/Jcs.01229  0.136
2009 Stein GS, Zaidi SK, Stein JL, Lian JB, van Wijnen AJ, Montecino M, Young DW, Javed A, Pratap J, Choi JY, Ali SA, Pande S, Hassan MQ. Organization, integration, and assembly of genetic and epigenetic regulatory machinery in nuclear microenvironments: implications for biological control in cancer. Annals of the New York Academy of Sciences. 1155: 4-14. PMID 19250187 DOI: 10.1111/J.1749-6632.2009.03697.X  0.135
2005 Barraclough P, Spray CA, Young DW. Synthesis of (2S,3R)- and (2S,3S)-[3-2H1]-proline via highly stereoselective hydrolysis of a silyl enol ether Tetrahedron Letters. 46: 4653-4655. DOI: 10.1016/J.Tetlet.2005.04.126  0.134
2008 van der Deen M, Hassan MQ, Pratap J, Teplyuk NM, Young DW, Javed A, Zaidi SK, Lian JB, Montecino M, Stein JL, Stein GS, van Wijnen AJ. Chromatin immunoprecipitation assays: application of ChIP-on-chip for defining dynamic transcriptional mechanisms in bone cells. Methods in Molecular Biology (Clifton, N.J.). 455: 165-76. PMID 18463819 DOI: 10.1007/978-1-59745-104-8_13  0.133
2000 Adams B, Beresford KJM, Whyte SM, Young DW. Stereochemistry of the reaction of the inhibitor β-chloroalanine with mercaptoethanol, a β-substitution reaction catalysed by an aminotransferase Chemical Communications. 619-620. DOI: 10.1039/B000442L  0.133
2004 Charrier JD, Hitchcock PB, Young DW. Synthesis of (2S,3R)-[3',3',3'-2H3]-valine and (2S,3S)-4-fluorovaline. Organic & Biomolecular Chemistry. 2: 1310-4. PMID 15105921 DOI: 10.1039/B401646G  0.131
2005 Duggan HM, Hitchcock PB, Young DW. Synthesis of 5/7-, 5/8- and 5/9-bicyclic lactam templates as constraints for external beta-turns. Organic & Biomolecular Chemistry. 3: 2287-95. PMID 16010363 DOI: 10.1039/B503014E  0.131
2010 Zaidi SK, Young DW, Montecino MA, Lian JB, van Wijnen AJ, Stein JL, Stein GS. Mitotic bookmarking of genes: a novel dimension to epigenetic control. Nature Reviews. Genetics. 11: 583-9. PMID 20628351 DOI: 10.1038/Nrg2827  0.13
2003 Alexeev D, Barlow PN, Bury SM, Charrier JD, Cooper A, Hadfield D, Jamieson C, Kelly SM, Layfield R, Mayer RJ, McSparron H, Price NC, Ramage R, Sawyer L, Starkmann BA, ... ... Young DW, et al. Synthesis, structural and biological studies of ubiquitin mutants containing (2S, 4S)-5-fluoroleucine residues strategically placed in the hydrophobic core. Chembiochem : a European Journal of Chemical Biology. 4: 894-6. PMID 12964166 DOI: 10.1002/Cbic.200300699  0.129
2005 Galindo M, Pratap J, Young DW, Hovhannisyan H, Im HJ, Choi JY, Lian JB, Stein JL, Stein GS, van Wijnen AJ. The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts. The Journal of Biological Chemistry. 280: 20274-85. PMID 15781466 DOI: 10.1074/Jbc.M413665200  0.127
1999 Capps NK, Davies GM, McCabe RW, Young DW. Oxidative rearrangement of 2-vinyl-1,3-thiazetidines Journal of the Chemical Society - Perkin Transactions 1. 3569-3571. DOI: 10.1039/A907657C  0.126
2011 Stein GS, Stein JL, van Wijnen AJ, Lian JB, Zaidi SK, Nickerson JA, Montecino MA, Young DW. An architectural genetic and epigenetic perspective. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 297-303. PMID 21184003 DOI: 10.1039/C0Ib00103A  0.126
2005 Lowpetch K, Young DW. A short, versatile chemical synthesis of L- and D-amino acids stereoselectively labelled solely in the beta position. Organic & Biomolecular Chemistry. 3: 3348-56. PMID 16132096 DOI: 10.1039/B508196C  0.125
2006 Pockwinse SM, Rajgopal A, Young DW, Mujeeb KA, Nickerson J, Javed A, Redick S, Lian JB, van Wijnen AJ, Stein JL, Stein GS, Doxsey SJ. Microtubule-dependent nuclear-cytoplasmic shuttling of Runx2. Journal of Cellular Physiology. 206: 354-62. PMID 16110492 DOI: 10.1002/Jcp.20469  0.125
2008 Pockwinse SM, Zaidi SK, Medina RF, Bakshi R, Kota KP, Ali SA, Young DW, Nickerson JA, Javed A, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. In situ nuclear organization of regulatory machinery. Methods in Molecular Biology (Clifton, N.J.). 455: 239-59. PMID 18463823 DOI: 10.1007/978-1-59745-104-8_17  0.123
2007 Rajgopal A, Young DW, Mujeeb KA, Stein JL, Lian JB, van Wijnen AJ, Stein GS. Mitotic control of RUNX2 phosphorylation by both CDK1/cyclin B kinase and PP1/PP2A phosphatase in osteoblastic cells. Journal of Cellular Biochemistry. 100: 1509-17. PMID 17171635 DOI: 10.1002/Jcb.21137  0.121
2005 Tavassoli A, Duffy JES, Young DW. Synthesis of trimethyl (2S,3R)- and (2R,3R)-[2-2H 1]-homocitrates and the corresponding dimethyl ester lactones-towards elucidating the stereochemistry of the reaction catalysed by homocitrate synthase and by the Nif-V protein Tetrahedron Letters. 46: 2093-2096. DOI: 10.1016/J.Tetlet.2005.01.134  0.121
2006 Barraclough P, Dieterich P, Spray CA, Young DW. Two separate and distinct syntheses of stereospecifically deuteriated samples of (2S)-proline. Organic & Biomolecular Chemistry. 4: 1483-91. PMID 16604215 DOI: 10.1039/B601097K  0.121
2000 Baker SJ, Young DW. Synthesis of 3,4-dihydro-5-[11C]methoxy-1(2H)-isoquinolinone as a potential tracer for Poly(ADP-ribose) synthetase Journal of Labelled Compounds and Radiopharmaceuticals. 43: 983-988. DOI: 10.1002/1099-1344(200009)43:10<983::AID-JLCR383>3.0.CO;2-C  0.12
2024 Tang SA, Fults A, Boyd SR, Gattu N, Tran KA, Fan J, MacKenzie KR, Palzkill T, Young DW, Chamakuri S. Expanding Complex Morpholines Using Systematic Chemical Diversity. Organic Letters. PMID 38506470 DOI: 10.1021/acs.orglett.4c00528  0.12
2023 Qin X, Wang Y, MacKenzie KR, Hakenjos JM, Chen S, Khalil SM, Jung SY, Young DW, Guo L, Li F. Identifying the Reactive Metabolites of Tyrosine Kinase Inhibitor Pexidartinib In Vitro Using LC-MS-Based Metabolomic Approaches. Chemical Research in Toxicology. PMID 37531179 DOI: 10.1021/acs.chemrestox.3c00164  0.119
2020 Boyd SR, Chang L, Rezende WC, Raji IO, Kandel P, Holmes SL, Young DW. Design and Applications of Bifunctional Small Molecules in Biology. Biochimica Et Biophysica Acta. Proteins and Proteomics. 140534. PMID 32871274 DOI: 10.1016/j.bbapap.2020.140534  0.118
2006 Tavassoli A, Duffy JE, Young DW. Synthesis of trimethyl (2S,3R)- and (2R,3R)-[2-2H1]-homocitrates and dimethyl (2S,3R)- and (2R,3R)-[2-2H1]-homocitrate lactones-an assay for the stereochemical outcome of the reaction catalysed both by homocitrate synthase and by the Nif-V protein. Organic & Biomolecular Chemistry. 4: 569-80. PMID 16446817 DOI: 10.1039/B515937G  0.117
2004 Young DW. The step-down to two hundred in Genesis 11,10-25 Zeitschrift Fur Die Alttestamentliche Wissenschaft. 116: 323-333. DOI: 10.1515/zatw.2004.116.3.323  0.116
2023 Han X, Wang W, Ma LH, Al-Ramahi I, Botas J, MacKenzie K, Allen GI, Young DW, Liu Z, Maletic-Savatic M. SPA-STOCSY: An Automated Tool for Identification of Annotated and Non-Annotated Metabolites in High-Throughput NMR Spectra. Biorxiv : the Preprint Server For Biology. PMID 36865102 DOI: 10.1101/2023.02.22.529564  0.112
2008 Stein GS, Lian JB, Montecino M, Van Wijnen J, Stein JL, Javed A, Young DW, Hassan MQ, Zaidi SK. Skeletal Gene Expression in Nuclear Microenvironments Principles of Bone Biology, Two-Volume Set. 1: 263-283. DOI: 10.1016/B978-0-12-373884-4.00033-1  0.112
2002 Coe D, Drysdale M, Philps O, West R, Young DW. Extension of the "ring switch" approach to glutamate antagonists to δ-lactam urethanes Journal of the Chemical Society. Perkin Transactions 1. 2459-2472.  0.109
2022 Teng M, Young DW, Tan Z. The Pursuit of Enzyme Activation: A Snapshot of the Gold Rush. Journal of Medicinal Chemistry. PMID 36265019 DOI: 10.1021/acs.jmedchem.2c01291  0.108
2007 Zaidi SK, Young DW, Javed A, Pratap J, Montecino M, van Wijnen A, Lian JB, Stein JL, Stein GS. Nuclear microenvironments in biological control and cancer. Nature Reviews. Cancer. 7: 454-63. PMID 17522714 DOI: 10.1038/Nrc2149  0.108
2004 Charrier JD, Hadfield DS, Hitchcock PB, Young DW. Synthesis of (2S,4S)- and (2S,4R)-5-fluoroleucine and (2S,4S)-[5,5-2H2]-5-fluoroleucine. Organic & Biomolecular Chemistry. 2: 474-82. PMID 14770225 DOI: 10.1039/B314933A  0.106
2003 Hitchcock PB, Rahman S, Young DW. An alternative to the use of δ-lactam urethanes in the "ring switch" approach to higher homologues of AMPA-type glutamate antagonists Organic and Biomolecular Chemistry. 1: 2682-2688. DOI: 10.1039/b304609p  0.104
2005 Adams B, Lowpetch K, Thorndycroft F, Whyte SM, Young DW. Stereochemistry of reactions of the inhibitor/substrates L- and D-beta-chloroalanine with beta-mercaptoethanol catalysed by L-aspartate aminotransferase and D-amino acid aminotransferase respectively. Organic & Biomolecular Chemistry. 3: 3357-64. PMID 16132097 DOI: 10.1039/B508199H  0.101
1999 Chow JC, Young DW, Golenbock DT, Christ WJ, Gusovsky F. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. The Journal of Biological Chemistry. 274: 10689-92. PMID 10196138 DOI: 10.1074/jbc.274.16.10689  0.1
2022 Bokhari RS, Beheshti A, Blutt SE, Bowles DE, Brenner D, Britton R, Bronk L, Cao X, Chatterjee A, Clay DE, Courtney C, Fox DT, Gaber MW, Gerecht S, Grabham P, ... ... Young DW, et al. Looking on the horizon; potential and unique approaches to developing radiation countermeasures for deep space travel. Life Sciences in Space Research. 35: 105-112. PMID 36336356 DOI: 10.1016/j.lssr.2022.08.003  0.098
2008 Stein GS, Zaidi SK, Stein JL, Lian JB, van Wijnen AJ, Montecino M, Young DW, Javed A, Pratap J, Choi JY, Ali SA, Pande S, Hassan MQ. Genetic and epigenetic regulation in nuclear microenvironments for biological control in cancer. Journal of Cellular Biochemistry. 104: 2016-26. PMID 18615590 DOI: 10.1002/Jcb.21813  0.098
2022 McNerlin C, Guan F, Bronk L, Lei K, Grosshans D, Young DW, Gaber MW, Maletic-Savatic M. Targeting hippocampal neurogenesis to protect astronauts' cognition and mood from decline due to space radiation effects. Life Sciences in Space Research. 35: 170-179. PMID 36336363 DOI: 10.1016/j.lssr.2022.07.007  0.094
2009 Fletcher BW, Lehman WEK, Wexler HK, Melnick G, Taxman FS, Young DW. Measuring collaboration and integration activities in criminal justice and substance abuse treatment agencies Drug and Alcohol Dependence. 103: S54-S64. PMID 20088023 DOI: 10.1016/J.Drugalcdep.2009.01.001  0.09
2006 Young DW, Ballarin E. Strategic decision-making in healthcare organizations: it is time to get serious. The International Journal of Health Planning and Management. 21: 173-91. PMID 17044545 DOI: 10.1002/hpm.844  0.088
2001 Okamura Y, Watari M, Jerud ES, Young DW, Ishizaka ST, Rose J, Chow JC, Strauss JF. The extra domain A of fibronectin activates Toll-like receptor 4. The Journal of Biological Chemistry. 276: 10229-33. PMID 11150311 DOI: 10.1074/jbc.M100099200  0.086
2022 Kandel P, Semerci F, Mishra R, Choi W, Bajic A, Baluya D, Ma L, Chen K, Cao AC, Phongmekhin T, Matinyan N, Jiménez-Panizo A, Chamakuri S, Raji IO, Chang L, ... ... Young DW, et al. Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis. Proceedings of the National Academy of Sciences of the United States of America. 119: e2023784119. PMID 35333654 DOI: 10.1073/pnas.2023784119  0.085
2000 Yang H, Young DW, Gusovsky F, Chow JC. Cellular events mediated by lipopolysaccharide-stimulated toll-like receptor 4. MD-2 is required for activation of mitogen-activated protein kinases and Elk-1 Journal of Biological Chemistry. 275: 20861-20866. PMID 10877845 DOI: 10.1074/jbc.M002896200  0.077
2020 Maletic-Savatic M, Li Y, Young D, Elvsåshagen T, Loo C, Reneman L, Lucassen PJ, Calarge C, Valenzuela M. Fatty Acids as Biomarkers of Neurogenesis and New Targets for Treatment of Depression Biological Psychiatry. 87: S59. DOI: 10.1016/J.Biopsych.2020.02.174  0.077
2004 Young DW. Improving operating room performance in a center of excellence. Healthcare Financial Management : Journal of the Healthcare Financial Management Association. 58: 70-4. PMID 15372812  0.076
2001 Young DW, Barrett D, Kenagy JW, Pinakiewicz DC, McCarthy SM. Value-based partnering in healthcare: a framework for analysis. Journal of Healthcare Management / American College of Healthcare Executives. 46: 112-32; discussion 1. PMID 11277013  0.074
2007 Taxman FS, Cropsey KL, Young DW, Wexler H. SCREENING, ASSESSMENT, AND REFERRAL PRACTICES IN ADULT CORRECTIONAL SETTINGS : A National Perspective. Criminal Justice and Behavior. 34: 1216-1234. PMID 18458758 DOI: 10.1177/0093854807304431  0.073
2010 Juarez JC, Sluz JE, Nelson C, Davidson FM, Young DW, Sova RM. Lasercomm demonstration in a maritime environment for tactical applications Optics Infobase Conference Papers 0.073
2023 Han X, Wang W, Ma LH, Ai-Ramahi I, Botas J, MacKenzie K, Allen GI, Young DW, Liu Z, Maletic-Savatic M. SPA-STOCSY: an automated tool for identifying annotated and non-annotated metabolites in high-throughput NMR spectra. Bioinformatics (Oxford, England). 39. PMID 37792497 DOI: 10.1093/bioinformatics/btad593  0.067
2006 Dieterich P, Young DW. Synthesis of (2S,3S)-[3-(2)H1]-4-methyleneglutamic acid and (2S,3R)-[2,3-(2)H2]-4-methyleneglutamic acid. Organic & Biomolecular Chemistry. 4: 1492-6. PMID 16604216 DOI: 10.1039/B601098A  0.067
2021 Bowling EA, Wang JH, Gong F, Wu W, Neill NJ, Kim IS, Tyagi S, Orellana M, Kurley SJ, Dominguez-Vidaña R, Chung HC, Hsu TY, Dubrulle J, Saltzman AB, Li H, ... ... Young DW, et al. Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer. Cell. PMID 33450205 DOI: 10.1016/j.cell.2020.12.031  0.067
2022 Qin X, Xie C, Hakenjos JM, MacKenzie KR, Boyd SR, Barzi M, Bissig KD, Young DW, Li F. The roles of Cyp1a2 and Cyp2d in pharmacokinetic profiles of serotonin and norepinephrine reuptake inhibitor duloxetine and its metabolites in mice. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 181: 106358. PMID 36513193 DOI: 10.1016/j.ejps.2022.106358  0.067
2011 Farrell JL, Young DW, Taxman FS. Effects of organizational factors on use of juvenile supervision practices Criminal Justice and Behavior. 38: 565-583. DOI: 10.1177/0093854811401786  0.067
2001 Young DW, McCarthy SM, Barrett D, Kenagy JW, Pinakiewicz DC. Beyond health care cost containment: creating collaborative arrangements among the stakeholders. The International Journal of Health Planning and Management. 16: 207-28. PMID 11596558 DOI: 10.1002/hpm.631  0.065
1999 Young DW, Rosenthal D. Couples' experience of illness: The daily lives of patients and spouses Families, Systems and Health. 17: 265-285.  0.064
2007 Sarath VJ, So CS, Young DW, Gollapudi S. Artemisia princeps var orientalis induces apoptosis in human breast cancer MCF-7 cells Anticancer Research. 27: 3891-3898. PMID 18225547  0.062
2007 Henderson CE, Young DW, Jainchill N, Hawke J, Farkas S, Davis RM. Program use of effective drug abuse treatment practices for juvenile offenders. Journal of Substance Abuse Treatment. 32: 279-90. PMID 17383552 DOI: 10.1016/j.jsat.2006.12.021  0.062
2006 Young DW. Missing elements in the healthcare debate. Healthcare Financial Management : Journal of the Healthcare Financial Management Association. 60: 94-8. PMID 16927501  0.06
2000 Young DW, McCarthy SM. Aligning physician financial incentives in a mixed-payment environment. Healthcare Financial Management : Journal of the Healthcare Financial Management Association. 54: 46-55. PMID 11183544  0.06
2011 Juarez JC, Young DW, Sluz JE, Stotts LB. High-sensitivity DPSK receiver for high-bandwidth free-space optical communication links. Optics Express. 19: 10789-96. PMID 21643335 DOI: 10.1364/OE.19.010789  0.058
2008 Henderson CE, Taxman FS, Young DW. A Rasch model analysis of evidence-based treatment practices used in the criminal justice system. Drug and Alcohol Dependence. 93: 163-75. PMID 18029116 DOI: 10.1016/J.Drugalcdep.2007.09.010  0.057
2007 Cropsey KL, Wexler HK, Melnick G, Taxman FS, Young DW. Specialized Prisons and Services: Results From a National Survey. The Prison Journal. 87: 58-85. PMID 18443650 DOI: 10.1177/0032885506299043  0.055
1999 Young DW, Reinecke MA, Beebe D, Stein MA. WISC-III third factor [1] (multiple letters) Journal of the American Academy of Child and Adolescent Psychiatry. 38: 1207-1208. PMID 10517047  0.054
2004 Adair PM, Pine CM, Burnside G, Nicoll AD, Gillett A, Anwar S, Broukal Z, Chestnutt IG, Declerck D, Ping FX, Ferro R, Freeman R, Grant-Mills D, Gugushe T, Hunsrisakhun J, ... ... Young DW, et al. Familial and cultural perceptions and beliefs of oral hygiene and dietary practices among ethnically and socio-economicall diverse groups. Community Dental Health. 21: 102-11. PMID 15072479  0.053
2010 Juarez JC, Sluz JE, Nelson C, Airola MB, Fitch MJ, Young DW, Terry D, Davidson FM, Rottier JR, Sova RM. Free-space optical channel characterization in the maritime environment Proceedings of Spie - the International Society For Optical Engineering. 7685. DOI: 10.1117/12.852645  0.053
2009 Henderson CE, Young DW, Farrell J, Taxman FS. Associations among state and local organizational contexts: Use of evidence-based practices in the criminal justice system. Drug and Alcohol Dependence. 103: S23-32. PMID 19174321 DOI: 10.1016/J.Drugalcdep.2008.12.006  0.053
2011 Möller JC, Cron RQ, Young DW, Girschick HJ, Levy DM, Sherry DD, Kukita A, Saijo K, Pessler F. Corticosteroid-induced spinal epidural lipomatosis in the pediatric age group: report of a new case and updated analysis of the literature. Pediatric Rheumatology Online Journal. 9: 5. PMID 21284882 DOI: 10.1186/1546-0096-9-5  0.051
2009 Young DW, Farrell JL, Henderson CE, Taxman FS. Filling service gaps: Providing intensive treatment services for offenders. Drug and Alcohol Dependence. 103: S33-42. PMID 19261394 DOI: 10.1016/J.Drugalcdep.2009.01.003  0.051
2015 Al-Mubarak G, Bryant AS, Crawford JH, Dukes CM, Kelly DR, Young DW, Cleveland DC. Surgical and Anesthetic Management of a Mediastinal Fatty Tumor: Lipoblastoma. The Annals of Thoracic Surgery. 100: e97-8. PMID 26522578 DOI: 10.1016/j.athoracsur.2015.04.103  0.05
1998 Young DW. Two-part transfer pricing improves IDS financial control Healthcare Financial Management. 52: 56-65. PMID 10182278  0.05
2011 Fain ET, Mannion M, Pope E, Young DW, Laxer RM, Cron RQ. Brain cavernomas associated with en coup de sabre linear scleroderma: Two case reports. Pediatric Rheumatology Online Journal. 9: 18. PMID 21801349 DOI: 10.1186/1546-0096-9-18  0.049
2006 Avent AG, Loakes D, Young DW. Acylation of ambident vinylogous urethanes exocyclic to thiazolidines and reduced thiazines Journal of Chemical Research. 580-583. DOI: 10.3184/030823406778521365  0.046
2014 Juarez JC, Brown DM, Young DW. Antenna gain of actively compensated free-space optical communication systems under strong turbulence conditions. Optics Express. 22: 12551-62. PMID 24921373 DOI: 10.1364/OE.22.012551  0.045
2001 Greenacre CB, Young DW, Behrend EN, Wilson GH. Validation of a novel high-sensitivity radioimmunoassay procedure for measurement of total thyroxine concentration in psittacine birds and snakes. American Journal of Veterinary Research. 62: 1750-4. PMID 11703019 DOI: 10.2460/Ajvr.2001.62.1750  0.043
2013 Young DW, Farrell JL, Taxman FS. Impacts of Juvenile Probation Training Models on Youth Recidivism Justice Quarterly. 30: 1068-1089. DOI: 10.1080/07418825.2012.673633  0.043
2008 Young DW. Using bundled prices and deep discounts to obtain managed care contracts: seller beware! Healthcare Financial Management : Journal of the Healthcare Financial Management Association. 62: 98-102, 104. PMID 18839671  0.043
2013 Young DW. Fiscal strategy in an era of reform. Healthcare Financial Management : Journal of the Healthcare Financial Management Association. 67: 56-64. PMID 23360055  0.041
2003 Parker RW, Mouton CP, Young DW, Espino DV. Early recognition and treatment of calciphylaxis. Southern Medical Journal. 96: 53-5. PMID 12602715 DOI: 10.1097/01.SMJ.0000047841.53171.19  0.039
2007 Taxman FS, Young DW, Wiersema B, Rhodes A, Mitchell S. The National Criminal Justice Treatment Practices survey: multilevel survey methods and procedures. Journal of Substance Abuse Treatment. 32: 225-38. PMID 17383548 DOI: 10.1016/J.Jsat.2007.01.002  0.037
2007 Young DW, Dembo R, Henderson CE. A national survey of substance abuse treatment for juvenile offenders. Journal of Substance Abuse Treatment. 32: 255-66. PMID 17383550 DOI: 10.1016/J.Jsat.2006.12.018  0.036
2008 Young DW. Profit centers in clinical care departments: an idea whose time has gone. Healthcare Financial Management : Journal of the Healthcare Financial Management Association. 62: 66-71. PMID 19097609  0.032
2007 Young DW. The folly of using RCCs and RVUs for intermediate product costing. Healthcare Financial Management : Journal of the Healthcare Financial Management Association. 61: 100-6, 108. PMID 17427470  0.031
2005 Behrend EN, Weigand CM, Whitley EM, Refsal KR, Young DW, Kemppainen RJ. Corticosterone- and aldosterone-secreting adrenocortical tumor in a dog. Journal of the American Veterinary Medical Association. 226: 1662-6, 1659. PMID 15906564 DOI: 10.2460/Javma.2005.226.1662  0.03
2011 Juarez JC, Sluz JE, Young DW. Optical automatic gain controller for high-bandwidth free-space optical communication links Optics Infobase Conference Papers 0.03
2003 Young DW. Portions of a coptic discourse by Shenute (Vienna incipit list no. 44) Journal of Juristic Papyrology. 33: 231-271.  0.03
2006 Sova RM, Sluz JE, Young DW, Juarez JC, Dwivedi A, Demidovich NM, Graves JE, Northcott M, Douglass J, Phillips J, Driver D, McClarin A, Abelson D. 80 Gb/s free-space optical communication demonstration between an aerostat and a ground terminal Proceedings of Spie - the International Society For Optical Engineering. 6304. DOI: 10.1117/12.703216  0.029
2015 Young DW, Hurt HH, Sluz JE, Juarez JC. Development and demonstration of laser communications systems Johns Hopkins Apl Technical Digest (Applied Physics Laboratory). 33: 122-138.  0.029
2009 Farneti F, Padovani E, Young DW. Governance of outsourcing and contractual relationships The New Public Governance?: Emerging Perspectives On the Theory and Practice of Public Governance. 255-269. DOI: 10.4324/9780203861684  0.028
2014 Waller PRH, Young DW. The new world of diagnostic testing post-myriad Biotechnology Law Report. 33: 17-18. DOI: 10.1089/blr.2013.9847  0.028
2007 Young DW, Juarez JC, Sova R, Sluz J, Phillips J, Driver D, McClarin A, Northcott M, Graves JE. Multichannel high data rate transmission between ground and airborne platforms Proceedings of Spie - the International Society For Optical Engineering. 6457. DOI: 10.1117/12.701085  0.027
2001 Young DW, Pinakiewicz DC, McCarthy SM, Barrett D, Kenagy J. Value-based partnering in health care. Benefits Quarterly. 17: 18-25. PMID 11372470  0.027
2013 Juarez JC, Brown DM, Young DW. Strehl ratio simulation results under strong turbulence conditions for actively compensated free-space optical communication systems Proceedings of Spie - the International Society For Optical Engineering. 8732. DOI: 10.1117/12.2018965  0.027
2010 DePuy P, Young DW, Rowe SM. Extensive pulmonary laceration in pediatric trauma. Respiration; International Review of Thoracic Diseases. 79: 76. PMID 18560207 DOI: 10.1159/000140696  0.026
2009 Cunningham J, Foulke D, Goode T, Baber D, Gaughan B, Fletcher M, Young DW, Juarez JC, Sluz JE, Riggins JL, Stellings P. Long range field testing of free space optical communications terminals on mobile platforms Proceedings - Ieee Military Communications Conference Milcom. DOI: 10.1109/MILCOM.2009.5379846  0.026
2000 Young DW. Five leaves from a copy of Shenute's third canon Museon. 113: 263-294.  0.026
1998 Fan H, Tayahi MB, Young DW, Dutta NK, Webster R. Analogue and digital transmission using polymer optical fibre Electronics Letters. 34: 1999-2000.  0.026
2011 Stotts LB, Plasson N, Martin TW, Young DW, Juarez J. Progress towards reliable free-space optical networks Proceedings - Ieee Military Communications Conference Milcom. 1720-1726. DOI: 10.1109/MILCOM.2011.6127559  0.024
2007 Young DW. Independent forest monitoring: Seven years on International Forestry Review. 9: 563-574. DOI: 10.1505/ifor.9.1.563  0.024
2007 Young DW, Sluz JE, Juarez JC, Airola MB, Sova RM, Hurt H, Northcott M, Phillips J, McClaren A, Driver D, Abelson D, Foshee J. Demonstration of high data rate wavelength division multiplexed transmission over a 150 km free space optical link Proceedings - Ieee Military Communications Conference Milcom. DOI: 10.1109/MILCOM.2007.4454950  0.024
2004 Young DW. The sexagesimal basis for the total years of the antediluvian and postdiluvian epochs Zeitschrift Fur Die Alttestamentliche Wissenschaft. 116: 502-527. DOI: 10.1515/zatw.2004.116.4.502  0.023
2011 Young DW. Bumps along the ACO road. Healthcare Financial Management : Journal of the Healthcare Financial Management Association. 65: 102-4, 106, 108. PMID 22292335  0.021
2007 Northcot MJ, McClaren A, Graves JE, Phillips J, Driver D, Abelson D, Young DW, Sluz JE, Juarez JC, Airola MB, Sova RM, Hurt H, Foshee J. Long distance laser communications demonstration Proceedings of Spie - the International Society For Optical Engineering. 6578. DOI: 10.1117/12.722320  0.021
2015 Mockford EL, Young DW. New Species and Records of Indiopsocus Mockford (Psocodea: 'Psocoptera': Psocidae) from Texas Transactions of the American Entomological Society. 141: 233-251. DOI: 10.3157/061.141.0114  0.021
2012 Sluz JE, Juarez JC, Bair CH, Oberc RL, Venkat RA, Rollend D, Young DW. High-performance free-space optical modem hardware Proceedings of Spie - the International Society For Optical Engineering. 8380. DOI: 10.1117/12.919926  0.021
2012 Juarez JC, Young DW, Venkat RA, Brown DM, Brown AM, Oberc RL, Sluz JE, Pike HA, Stotts LB. Analysis of link performance for the FOENEX laser communications system Proceedings of Spie - the International Society For Optical Engineering. 8380. DOI: 10.1117/12.919928  0.02
2013 Venkat RA, Young DW. Cloud-free line-of-sight estimation for free space optical communications Proceedings of Spie - the International Society For Optical Engineering. 8732. DOI: 10.1117/12.2019269  0.02
2007 Taxman FS, Young DW, Fletcher BW. The National Criminal Justice Treatment Practices survey: an overview of the special issue. Journal of Substance Abuse Treatment. 32: 221-3. PMID 17383547 DOI: 10.1016/J.Jsat.2006.12.017  0.02
2009 Stotts LB, Andrews LC, Cherry PC, Foshee JJ, Kolodzy PJ, McIntire WK, Northcott M, Phillips RL, Pike HA, Stadler B, Young DW. Hybrid optical RF airborne communications Proceedings of the Ieee. 97: 1109-1127. DOI: 10.1109/JPROC.2009.2014969  0.019
2013 Young DW. "You feel so out of place": Germantown's j. gordon baugh and the 1913 commemoration of the emancipation proclamation Pennsylvania Magazine of History and Biography. 137: 79-93. DOI: 10.5215/pennmaghistbio.137.1.0079  0.018
2003 Young DW. GME: at what cost? Healthcare Financial Management : Journal of the Healthcare Financial Management Association. 57: 42-4, 47-8. PMID 14626704  0.018
2007 Juarez JC, Dwivedi A, Sova RM, Sluz JE, Young DW. Field test of an air-to-ground communication link using a bare optical fiber Proceedings of Spie - the International Society For Optical Engineering. 6546. DOI: 10.1117/12.716057  0.018
2011 Juarez JC, Young DW, Sluz JE, Riggins JL, Hughes DH. Free-space optical channel propagation tests over a 147-km link Proceedings of Spie - the International Society For Optical Engineering. 8038. DOI: 10.1117/12.886890  0.018
2012 Bagley ZC, Hughes DH, Juarez JC, Kolodzy P, Martin T, Northcott M, Pike HA, Plasson ND, Stadler B, Stotts LB, Young DW. Hybrid optical radio frequency airborne communications Optical Engineering. 51. DOI: 10.1117/1.OE.51.5.055006  0.017
2006 Young DW. An edition of two folios from a shenoutean discourse against the devil Journal of Juristic Papyrology. 36: 167-187.  0.016
2010 Sluz JE, Riggins J, Juarez JC, Sova RM, Young DW, Nelson C. Characterization of data transmission through a maritime free-space optical channel with a custom bit error rate tester Proceedings of Spie - the International Society For Optical Engineering. 7700. DOI: 10.1117/12.852642  0.016
2014 Young DW. Self-measure of heart rate variability (HRV) and arrhythmia to monitor and to manage atrial arrhythmias: personal experience with high intensity interval exercise (HIIE) for the conversion to sinus rhythm. Frontiers in Physiology. 5: 251. PMID 25071596 DOI: 10.3389/fphys.2014.00251  0.016
2011 Riggins JL, Sluz JE, Juarez JC, Young DW. Customized bit error rate (cBERT) tester for characterizing frequent fade communications channels Optics Infobase Conference Papers 0.016
2015 Waller PR, Young DW. Diagnostic patenting since Myriad: an update. Mlo: Medical Laboratory Observer. 47: 46. PMID 26281097  0.016
2000 Young DW. The six levers for managing organizational culture Business Horizons. 43: 19-28.  0.015
2004 Young DW. A sequential inventory of manuscripts of Shenute's Ninth Canon Journal of Juristic Papyrology. 34: 141-169.  0.015
2011 Juarez JC, Sluz JE, Oberc RL, Young DW. 40-Gbps modem architecture for free-space optical communications Proceedings - Ieee Military Communications Conference Milcom. 578-582. DOI: 10.1109/MILCOM.2011.6127735  0.014
2011 Fletcher TM, Cunningham J, Baber D, Wickholm D, Goode T, Gaughan B, Burgan S, Deck A, Young DW, Juan J, Sluz J, Cohen J, Stallings P, Stadler BK. Observations of atmospheric effects for FALCON laser communication system flight test Proceedings of Spie - the International Society For Optical Engineering. 8038. DOI: 10.1117/12.887407  0.014
2013 Sunil B, Reddy A, Bryant N, Young DW, Ashraf AP. Invasive giant prolactinoma presenting as a nasal polyp. The Journal of Pediatrics. 162: 435-435.e1. PMID 23026487 DOI: 10.1016/j.jpeds.2012.08.029  0.014
2001 Kenagy JW, McCarthy SM, Young DW, Barrett D, Pinakiewicz DC. Toward a value-based health care system. The American Journal of Medicine. 110: 158-63. PMID 11165563 DOI: 10.1016/S0002-9343(00)00703-8  0.014
2015 Young DW. Missing elements in the institute of medicine report on graduate medical education. The American Journal of Medicine. 128: 558-61. PMID 25614956 DOI: 10.1016/j.amjmed.2015.01.004  0.013
2014 Padovani E, Orelli RL, Young DW. Implementing Change in a Hospital Management Accounting System Public Management Review. 16: 1184-1204. DOI: 10.1080/14719037.2013.792383  0.011
2009 Stotts LB, Stadler B, Kolodzy P, Pike A, Moore TG, Young DW, Smith R, Bagley Z, Plasson N, Graves B, Daugherty D, Douglas J, Martin T. Optical RF communications adjunct: Coming of age 2009 Ieee Avionics, Fiber-Optics and Photonics Technology Conference, Avfop'09. 74-75. DOI: 10.1109/AVFOP.2009.5342628  0.011
2005 Young DW. Strategic decision making: it's time for healthcare organizations to get serious. Healthcare Financial Management : Journal of the Healthcare Financial Management Association. 59: 86-90, 92. PMID 16323814  0.011
2013 Waller PR, Young DW. After the Myriad decision: do hurdles remain for diagnostics competition? Mlo: Medical Laboratory Observer. 45: 46. PMID 24147337  0.01
2012 Young DW. Intangible assets: The next accounting frontier Visualising Intangibles: Measuring and Reporting in the Knowledge Economy. 49-66.  0.01
2010 Young DW. Erratum: Corrigendum: An upfront investment Nature Chemical Biology. 6: 306-306. DOI: 10.1038/nchembio0410-306c  0.01
2009 Stotts LB, Stadler B, Hughes D, Kolodzy P, Pike A, Young DW, Sluz J, Juarez J, Graves B, Dougherty D, Douglass J, Martin T. Optical communications in atmospheric turbulence Proceedings of Spie - the International Society For Optical Engineering. 7464. DOI: 10.1117/12.831231  0.01
2004 Kendall P, Mangham C, Young DW. An ounce of prevention. Paediatrics & Child Health. 9: 151-2. PMID 19654996  0.01
2001 Young DW, Kohles SS. Experimental characterization of bone anisotropic poroelasticity parameters Bioengineering, Proceedings of the Northeast Conference. 41-42.  0.01
Hide low-probability matches.