Sara W. Leung, Ph.D. - Publications

Affiliations: 
2000 Emory University, Atlanta, GA 
Area:
Cell Biology, Molecular Biology, Genetics

23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 de Amorim JL, Leung SW, Haji-Seyed-Javadi R, Hou Y, Yu DS, Ghalei H, Khoshnevis S, Yao B, Corbett AH. The putative RNA helicase DDX1 associates with the nuclear RNA exosome and modulates RNA/DNA hybrids (R-loops). The Journal of Biological Chemistry. 105646. PMID 38219817 DOI: 10.1016/j.jbc.2024.105646  0.344
2023 Fasken MB, Leung SW, Cureton LA, Al-Awadi M, Al-Kindy A, Khoshnevis S, Ghalei H, Al-Maawali A, Corbett AH. A Biallelic Variant of the RNA Exosome Gene Causes Translational Defects Associated with a Neurodevelopmental Disorder. Medrxiv : the Preprint Server For Health Sciences. PMID 37961665 DOI: 10.1101/2023.10.24.23297197  0.313
2023 de Amorim JL, Leung SW, Haji-Seyed-Javadi R, Hou Y, Yu DS, Ghalei H, Khoshnevis S, Yao B, Corbett AH. The RNA helicase DDX1 associates with the nuclear RNA exosome and modulates R-loops. Biorxiv : the Preprint Server For Biology. PMID 37131662 DOI: 10.1101/2023.04.17.537228  0.347
2021 Sterrett MC, Enyenihi L, Leung SW, Hess L, Strassler SE, Farchi D, Lee RS, Withers ES, Kremsky I, Baker RE, Basrai MA, van Hoof A, Fasken MB, Corbett AH. A Budding Yeast Model for Human Disease Mutations in the Cap Subunit of the RNA Exosome. Rna (New York, N.Y.). PMID 34162742 DOI: 10.1261/rna.078618.120  0.343
2020 Morton DJ, Jalloh B, Kim L, Kremsky I, Nair RJ, Nguyen KB, Rounds JC, Sterrett MC, Brown B, Le T, Karkare MC, McGaughey KD, Sheng S, Leung SW, Fasken MB, et al. A Drosophila model of Pontocerebellar Hypoplasia reveals a critical role for the RNA exosome in neurons. Plos Genetics. 16: e1008901. PMID 32645003 DOI: 10.1371/Journal.Pgen.1008901  0.432
2020 Slavotinek A, Misceo D, Htun S, Mathisen L, Frengen E, Foreman M, Hurtig JE, Enyenihi L, Sterrett MC, Leung SW, Schneidman-Duhovny D, Estrada-Veras J, Duncan JL, Haaxma CA, Kamsteeg EJ, et al. Biallelic variants in the RNA exosome gene EXOSC5 are associated with developmental delays, short stature, cerebellar hypoplasia and motor weakness. Human Molecular Genetics. PMID 32504085 DOI: 10.1093/Hmg/Ddaa108  0.399
2020 Fasken MB, Morton DJ, Kuiper EG, Jones SK, Leung SW, Corbett AH. The RNA Exosome and Human Disease. Methods in Molecular Biology (Clifton, N.J.). 2062: 3-33. PMID 31768969 DOI: 10.1007/978-1-4939-9822-7_1  0.394
2020 de Amorim J, Leung S, van Hoof A, Corbett A. Identification of RNA Exosome Cofactors in Neuronal Cells to Probe Disease Mechanism The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05887  0.362
2020 Corbett AH, Leung SW, Sterrett MC, de Amorim J, Enyenihi LC, Morton DJ, van Hoof A, Fasken MB. The RNA Exosome and Genetic Disease The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00217  0.346
2017 Morton DJ, Kuiper EG, Jones SK, Leung SW, Corbett AH, Fasken MB. The RNA Exosome and RNA Exosome-linked Disease. Rna (New York, N.Y.). PMID 29093021 DOI: 10.1261/Rna.064626.117  0.409
2017 Bienkowski RS, Banerjee A, Rounds JC, Rha J, Omotade OF, Gross C, Morris KJ, Leung SW, Pak C, Jones SK, Santoro MR, Warren ST, Zheng JQ, Bassell GJ, Corbett AH, et al. The Conserved, Disease-Associated RNA Binding Protein dNab2 Interacts with the Fragile X Protein Ortholog in Drosophila Neurons. Cell Reports. 20: 1372-1384. PMID 28793261 DOI: 10.1016/J.Celrep.2017.07.038  0.377
2017 Rha J, Jones SK, Fidler J, Banerjee A, Leung SW, Morris KJ, Wong JC, Inglis GAS, Shapiro L, Deng Q, Cutler AA, Hanif AM, Pardue MT, Schaffer A, Seyfried NT, et al. The RNA-binding Protein, ZC3H14, is Required for Proper Poly(A) Tail Length Control, Expression of Synaptic Proteins, and Brain Function in Mice. Human Molecular Genetics. PMID 28666327 DOI: 10.1093/Hmg/Ddx248  0.398
2016 Fasken MB, Losh JS, Leung SW, Brutus S, Avin B, Vaught JC, Potter-Birriel J, Craig T, Tsanova B, Conn GL, Mills-Lujan K, Corbett AH, van Hoof A. Insight into the RNA Exosome Complex Through Modeling Pontocerebellar Hypoplasia Type 1b Disease Mutations in Yeast. Genetics. PMID 27777260 DOI: 10.1534/Genetics.116.195917  0.433
2014 Kelly SM, Leung SW, Pak C, Banerjee A, Moberg KH, Corbett AH. A conserved role for the zinc finger polyadenosine RNA binding protein, ZC3H14, in control of poly(A) tail length. Rna (New York, N.Y.). 20: 681-8. PMID 24671764 DOI: 10.1261/Rna.043984.113  0.438
2011 Fasken MB, Leung SW, Banerjee A, Kodani MO, Chavez R, Bowman EA, Purohit MK, Rubinson ME, Rubinson EH, Corbett AH. Air1 zinc knuckles 4 and 5 and a conserved IWRXY motif are critical for the function and integrity of the Trf4/5-Air1/2-Mtr4 polyadenylation (TRAMP) RNA quality control complex. The Journal of Biological Chemistry. 286: 37429-45. PMID 21878619 DOI: 10.1074/Jbc.M111.271494  0.349
2011 Pak C, Garshasbi M, Kahrizi K, Gross C, Apponi LH, Noto JJ, Kelly SM, Leung SW, Tzschach A, Behjati F, Abedini SS, Mohseni M, Jensen LR, Hu H, Huang B, et al. Mutation of the conserved polyadenosine RNA binding protein, ZC3H14/dNab2, impairs neural function in Drosophila and humans. Proceedings of the National Academy of Sciences of the United States of America. 108: 12390-5. PMID 21734151 DOI: 10.1073/Pnas.1107103108  0.458
2010 Kelly SM, Leung SW, Apponi LH, Bramley AM, Tran EJ, Chekanova JA, Wente SR, Corbett AH. Recognition of polyadenosine RNA by the zinc finger domain of nuclear poly(A) RNA-binding protein 2 (Nab2) is required for correct mRNA 3'-end formation. The Journal of Biological Chemistry. 285: 26022-32. PMID 20554526 DOI: 10.1074/Jbc.M110.141127  0.442
2010 Apponi LH, Leung SW, Williams KR, Valentini SR, Corbett AH, Pavlath GK. Loss of nuclear poly(A)-binding protein 1 causes defects in myogenesis and mRNA biogenesis. Human Molecular Genetics. 19: 1058-65. PMID 20035013 DOI: 10.1093/Hmg/Ddp569  0.386
2009 Leung SW, Apponi LH, Cornejo OE, Kitchen CM, Valentini SR, Pavlath GK, Dunham CM, Corbett AH. Splice variants of the human ZC3H14 gene generate multiple isoforms of a zinc finger polyadenosine RNA binding protein. Gene. 439: 71-8. PMID 19303045 DOI: 10.1016/J.Gene.2009.02.022  0.414
2006 Zhao Q, Leung S, Corbett AH, Meier I. Identification and characterization of the Arabidopsis orthologs of nuclear transport factor 2, the nuclear import factor of ran. Plant Physiology. 140: 869-78. PMID 16428596 DOI: 10.1104/Pp.105.075499  0.338
2003 Leung SW, Harreman MT, Hodel MR, Hodel AE, Corbett AH. Dissection of the karyopherin alpha nuclear localization signal (NLS)-binding groove: functional requirements for NLS binding. The Journal of Biological Chemistry. 278: 41947-53. PMID 12917403 DOI: 10.1074/Jbc.M307162200  0.31
2002 Bayliss R, Leung SW, Baker RP, Quimby BB, Corbett AH, Stewart M. Structural basis for the interaction between NTF2 and nucleoporin FxFG repeats. The Embo Journal. 21: 2843-53. PMID 12065398 DOI: 10.1093/Emboj/Cdf305  0.305
2001 Quimby BB, Leung SW, Bayliss R, Harreman MT, Thirumala G, Stewart M, Corbett AH. Functional analysis of the hydrophobic patch on nuclear transport factor 2 involved in interactions with the nuclear pore in vivo. The Journal of Biological Chemistry. 276: 38820-9. PMID 11489893 DOI: 10.1074/Jbc.M105054200  0.326
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