Amy Kiernan - Publications

Affiliations: 
School of Medicine and Dentistry University of Rochester, Rochester, NY 
Area:
Human Development, Evolution and Development Biology, Cell Biology

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Heffer A, Lee C, Holt JC, Kiernan AE. is required to maintain supporting cell identity and vestibular function during maturation of the mammalian balance organs. Biorxiv : the Preprint Server For Biology. PMID 38948821 DOI: 10.1101/2024.06.21.600098  0.513
2022 Heffer A, Gilels FA, Kiernan AE. Deletion of during cochlear maturation leads to rapid supporting cell death and profound deafness. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 36418183 DOI: 10.1523/JNEUROSCI.1090-22.2022  0.522
2022 Gilels FA, Wang J, Bullen A, White PM, Kiernan AE. Deletion of the Notch ligand Jagged1 during cochlear maturation leads to inner hair cell defects and hearing loss. Cell Death & Disease. 13: 971. PMID 36400760 DOI: 10.1038/s41419-022-05380-w  0.541
2020 Brown RM, Nelson JC, Zhang H, Kiernan AE, Groves AK. Notch-mediated lateral induction is necessary to maintain vestibular prosensory identity during inner ear development. Developmental Biology. PMID 32147304 DOI: 10.1016/j.ydbio.2020.02.015  0.397
2019 Steevens AR, Glatzer JC, Kellogg CC, Low WC, Santi PA, Kiernan AE. SOX2 is required for inner ear growth and cochlear nonsensory formation prior to sensory development. Development (Cambridge, England). PMID 31152002 DOI: 10.1242/dev.170522  0.394
2018 Rausch RL, Libby RT, Kiernan AE. Trabecular meshwork morphogenesis: A comparative analysis of wildtype and anterior segment dysgenesis mouse models. Experimental Eye Research. PMID 29452107 DOI: 10.1016/J.Exer.2018.02.011  0.344
2018 Johnson KR, Gagnon LH, Tian C, Longo-Guess CM, Low BE, Wiles MV, Kiernan AE. Deletion of a Long-Range Dlx5 Enhancer Disrupts Inner Ear Development in Mice. Genetics. PMID 29301908 DOI: 10.1534/genetics.117.300447  0.314
2017 Sun W, Zhang H, Wang H, Chiu YG, Ritchlin CT, Kiernan A, Boyce BF, Xing L. Targeting Notch-activated M1 Macrophages Attenuates Joint Tissue Damage in a Mouse Model of Inflammatory Arthritis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 28256007 DOI: 10.1002/Jbmr.3117  0.334
2014 Savoy-Burke G, Gilels FA, Pan W, Pratt D, Que J, Gan L, White PM, Kiernan AE. Activated notch causes deafness by promoting a supporting cell phenotype in developing auditory hair cells. Plos One. 9: e108160. PMID 25264928 DOI: 10.1371/Journal.Pone.0108160  0.523
2013 Pan W, Jin Y, Chen J, Rottier RJ, Steel KP, Kiernan AE. Ectopic expression of activated notch or SOX2 reveals similar and unique roles in the development of the sensory cell progenitors in the mammalian inner ear. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 16146-57. PMID 24107947 DOI: 10.1523/Jneurosci.3150-12.2013  0.524
2013 Kiernan AE. Notch signaling during cell fate determination in the inner ear. Seminars in Cell & Developmental Biology. 24: 470-9. PMID 23578865 DOI: 10.1016/j.semcdb.2013.04.002  0.523
2013 Liu K, Jiang M, Lu Y, Chen H, Sun J, Wu S, Ku WY, Nakagawa H, Kita Y, Natsugoe S, Peters JH, Rustgi A, Onaitis MW, Kiernan A, Chen X, et al. Sox2 cooperates with inflammation-mediated Stat3 activation in the malignant transformation of foregut basal progenitor cells. Cell Stem Cell. 12: 304-15. PMID 23472872 DOI: 10.1016/J.Stem.2013.01.007  0.463
2010 Pan W, Jin Y, Stanger B, Kiernan AE. Notch signaling is required for the generation of hair cells and supporting cells in the mammalian inner ear. Proceedings of the National Academy of Sciences of the United States of America. 107: 15798-803. PMID 20733081 DOI: 10.1073/Pnas.1003089107  0.534
2006 Kiernan AE, Xu J, Gridley T. The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear. Plos Genetics. 2: e4. PMID 16410827 DOI: 10.1371/Journal.Pgen.0020004  0.523
2005 Kiernan AE, Cordes R, Kopan R, Gossler A, Gridley T. The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear. Development (Cambridge, England). 132: 4353-62. PMID 16141228 DOI: 10.1242/Dev.02002  0.533
2005 Kiernan AE, Pelling AL, Leung KKH, Tang ASP, Bell DM, Tease C, Lovell-Badge R, Steel KP, Cheah KSE. Sox2 is required for sensory organ development in the mammalian inner ear Nature. 434: 1031-1035. PMID 15846349 DOI: 10.1038/Nature03487  0.511
2003 Hulander M, Kiernan AE, Blomqvist SR, Carlsson P, Samuelsson EJ, Johansson BR, Steel KP, Enerbäck S. Lack of pendrin expression leads to deafness and expansion of the endolymphatic compartment in inner ears of Foxi1 null mutant mice. Development (Cambridge, England). 130: 2013-25. PMID 12642503  0.319
2001 Kiernan AE, Ahituv N, Fuchs H, Balling R, Avraham KB, Steel KP, Hrabé de Angelis M. The Notch ligand Jagged1 is required for inner ear sensory development. Proceedings of the National Academy of Sciences of the United States of America. 98: 3873-8. PMID 11259677 DOI: 10.1073/Pnas.071496998  0.513
2001 Tsai H, Hardisty RE, Rhodes C, Kiernan AE, Roby P, Tymowska-Lalanne Z, Mburu P, Rastan S, Hunter AJ, Brown SD, Steel KP. The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti. Human Molecular Genetics. 10: 507-12. PMID 11181574 DOI: 10.1093/hmg/10.5.507  0.329
1999 Kiernan AE, Zalzman M, Fuchs H, Hrabe de Angelis M, Balling R, Steel KP, Avraham KB. Tailchaser (Tlc): a new mouse mutation affecting hair bundle differentiation and hair cell survival. Journal of Neurocytology. 28: 969-85. PMID 10900098 DOI: 10.1023/A:1007090626294  0.402
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