Richard T. Libby - Publications

Affiliations: 
Opthalomology University of Rochester, Rochester, NY 
Area:
Retina, glaucoma

70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Syc-Mazurek SB, Rausch RL, Fernandes KA, Wilson MP, Libby RT. Author Correction: Mkk4 and Mkk7 are important for retinal development and axonal injury-induced retinal ganglion cell death. Cell Death & Disease. 10: 64. PMID 30683846 DOI: 10.1038/s41419-018-1233-2  0.6
2018 Syc-Mazurek SB, Rausch RL, Fernandes KA, Wilson MP, Libby RT. Mkk4 and Mkk7 are important for retinal development and axonal injury-induced retinal ganglion cell death. Cell Death & Disease. 9: 1095. PMID 30367030 DOI: 10.1038/s41419-018-1079-7  0.6
2018 Harder JM, Williams PA, Soto I, Foxworth NE, Fernandes KA, Freeburg NF, Libby RT, John SWM. Jnk2 deficiency increases the rate of glaucomatous neurodegeneration in ocular hypertensive DBA/2J mice. Cell Death & Disease. 9: 705. PMID 29899326 DOI: 10.1038/s41419-018-0705-8  0.96
2018 Fahrenthold BK, Fernandes KA, Libby RT. Assessment of intrinsic and extrinsic signaling pathway in excitotoxic retinal ganglion cell death. Scientific Reports. 8: 4641. PMID 29545615 DOI: 10.1038/s41598-018-22848-y  0.6
2018 Fernandes KA, Mitchell KL, Patel A, Marola OJ, Shrager P, Zack DJ, Libby RT, Welsbie DS. Role of SARM1 and DR6 in retinal ganglion cell axonal and somal degeneration following axonal injury. Experimental Eye Research. PMID 29526794 DOI: 10.1016/j.exer.2018.03.007  0.6
2017 Syc-Mazurek SB, Fernandes KA, Wilson MP, Shrager P, Libby RT. Together JUN and DDIT3 (CHOP) control retinal ganglion cell death after axonal injury. Molecular Neurodegeneration. 12: 71. PMID 28969695 DOI: 10.1186/s13024-017-0214-8  0.6
2017 Apara A, Galvao J, Wang Y, Blackmore M, Trillo A, Iwao K, Brown DP, Fernandes KA, Huang A, Nguyen T, Ashouri M, Zhang X, Shaw PX, Kunzevitzky NJ, Moore DL, ... Libby RT, et al. KLF9 and JNK3 Interact to Suppress Axon Regeneration in the Adult CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28871032 DOI: 10.1523/JNEUROSCI.0643-16.2017  0.6
2017 Syc-Mazurek SB, Fernandes KA, Libby RT. JUN is important for ocular hypertension-induced retinal ganglion cell degeneration. Cell Death & Disease. 8: e2945. PMID 28726785 DOI: 10.1038/cddis.2017.338  0.6
2017 Harder JM, Braine CE, Williams PA, Zhu X, MacNicoll KH, Sousa GL, Buchanan RA, Smith RS, Libby RT, Howell GR, John SWM. Early immune responses are independent of RGC dysfunction in glaucoma with complement component C3 being protective. Proceedings of the National Academy of Sciences of the United States of America. PMID 28446616 DOI: 10.1073/pnas.1608769114  0.96
2016 Alavi MV, Mao M, Pawlikowski BT, Kvezereli M, Duncan JL, Libby RT, John SW, Gould DB. Col4a1 mutations cause progressive retinal neovascular defects and retinopathy. Scientific Reports. 6: 18602. PMID 26813606 DOI: 10.1038/srep18602  1
2015 Fernandes KA, Bloomsburg SJ, Miller CJ, Billingslea SA, Merrill MM, Burgess RW, Libby RT, Fuerst PG. Novel axon projection after stress and degeneration in the Dscam mutant retina. Molecular and Cellular Neurosciences. 71: 1-12. PMID 26691152 DOI: 10.1016/j.mcn.2015.12.003  1
2015 Mao M, Smith RS, Alavi MV, Marchant JK, Cosma M, Libby RT, John SW, Gould DB. Strain-Dependent Anterior Segment Dysgenesis and Progression to Glaucoma in Col4a1 Mutant Mice. Investigative Ophthalmology & Visual Science. 56: 6823-6831. PMID 26567795 DOI: 10.1167/iovs.15-17527  1
2015 Hedberg-Buenz A, Christopher MA, Lewis CJ, Fernandes KA, Dutca LM, Wang K, Scheetz TE, Abramoff MD, Libby RT, Garvin MK, Anderson MG. Quantitative measurement of retinal ganglion cell populations via histology-based random forest classification. Experimental Eye Research. PMID 26474494 DOI: 10.1016/j.exer.2015.09.011  1
2015 Fernandes KA, Harder JM, Williams PA, Rausch RL, Kiernan AE, Nair KS, Anderson MG, John SW, Howell GR, Libby RT. Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities. Experimental Eye Research. PMID 26116903 DOI: 10.1016/j.exer.2015.06.019  1
2014 Mac Nair CE, Fernandes KA, Schlamp CL, Libby RT, Nickells RW. Tumor necrosis factor alpha has an early protective effect on retinal ganglion cells after optic nerve crush. Journal of Neuroinflammation. 11: 194. PMID 25407441 DOI: 10.1186/s12974-014-0194-3  0.6
2014 Soto I, Howell GR, John CW, Kief JL, Libby RT, John SW. DBA/2J mice are susceptible to diabetic nephropathy and diabetic exacerbation of IOP elevation. Plos One. 9: e107291. PMID 25207540 DOI: 10.1371/journal.pone.0107291  1
2014 Fernandes KA, Harder JM, John SW, Shrager P, Libby RT. DLK-dependent signaling is important for somal but not axonal degeneration of retinal ganglion cells following axonal injury. Neurobiology of Disease. 69: 108-16. PMID 24878510 DOI: 10.1016/j.nbd.2014.05.015  1
2014 Huang L, Hu F, Xie X, Harder J, Fernandes K, Zeng XY, Libby R, Gan L. Pou4f1 and pou4f2 are dispensable for the long-term survival of adult retinal ganglion cells in mice. Plos One. 9: e94173. PMID 24736625 DOI: 10.1371/journal.pone.0094173  1
2014 Coleman JA, Zhu X, Djajadi HR, Molday LL, Smith RS, Libby RT, John SW, Molday RS. Phospholipid flippase ATP8A2 is required for normal visual and auditory function and photoreceptor and spiral ganglion cell survival. Journal of Cell Science. 127: 1138-49. PMID 24413176 DOI: 10.1242/jcs.145052  1
2014 Strazzeri JM, Hunter JJ, Masella BD, Yin L, Fischer WS, DiLoreto DA, Libby RT, Williams DR, Merigan WH. Focal damage to macaque photoreceptors produces persistent visual loss. Experimental Eye Research. 119: 88-96. PMID 24316158 DOI: 10.1016/j.exer.2013.11.001  1
2013 Howell GR, Libby RT. Adding metabolomics to the toolbox for studying retinal disease. Investigative Ophthalmology & Visual Science. 54: 4260. PMID 23794537 DOI: 10.1167/iovs.13-12479  1
2013 Zhou Y, Tanzie C, Yan Z, Chen S, Duncan M, Gaudenz K, Li H, Seidel C, Lewis B, Moran A, Libby RT, Kiernan AE, Xie T. Notch2 regulates BMP signaling and epithelial morphogenesis in the ciliary body of the mouse eye. Proceedings of the National Academy of Sciences of the United States of America. 110: 8966-71. PMID 23676271 DOI: 10.1073/pnas.1218145110  1
2013 Jiang Y, Ding Q, Xie X, Libby RT, Lefebvre V, Gan L. Transcription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells. The Journal of Biological Chemistry. 288: 18429-38. PMID 23649630 DOI: 10.1074/jbc.M113.478503  1
2013 Fernandes KA, Harder JM, Kim J, Libby RT. JUN regulates early transcriptional responses to axonal injury in retinal ganglion cells. Experimental Eye Research. 112: 106-17. PMID 23648575 DOI: 10.1016/j.exer.2013.04.021  1
2013 Harder JM, Libby RT. Deficiency in Bim, Bid and Bbc3 (Puma) do not prevent axonal injury induced death. Cell Death and Differentiation. 20: 182. PMID 22996683 DOI: 10.1038/cdd.2012.119  1
2013 Howell GR, Soto I, Libby RT, John SW. Intrinsic axonal degeneration pathways are critical for glaucomatous damage. Experimental Neurology. 246: 54-61. PMID 22285251 DOI: 10.1016/j.expneurol.2012.01.014  1
2012 Zhu X, Libby RT, de Vries WN, Smith RS, Wright DL, Bronson RT, Seburn KL, John SW. Mutations in a P-type ATPase gene cause axonal degeneration. Plos Genetics. 8: e1002853. PMID 22912588 DOI: 10.1371/journal.pgen.1002853  1
2012 Harder JM, Ding Q, Fernandes KA, Cherry JD, Gan L, Libby RT. BCL2L1 (BCL-X) promotes survival of adult and developing retinal ganglion cells. Molecular and Cellular Neurosciences. 51: 53-9. PMID 22836101 DOI: 10.1016/j.mcn.2012.07.006  1
2012 Harder JM, Fernandes KA, Libby RT. The Bcl-2 family member BIM has multiple glaucoma-relevant functions in DBA/2J mice. Scientific Reports. 2: 530. PMID 22833783 DOI: 10.1038/srep00530  1
2012 Geng Y, Dubra A, Yin L, Merigan WH, Sharma R, Libby RT, Williams DR. Adaptive optics retinal imaging in the living mouse eye. Biomedical Optics Express. 3: 715-34. PMID 22574260 DOI: 10.1364/BOE.3.000715  1
2012 Howell GR, Soto I, Zhu X, Ryan M, Macalinao DG, Sousa GL, Caddle LB, MacNicoll KH, Barbay JM, Porciatti V, Anderson MG, Smith RS, Clark AF, Libby RT, John SW. Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma. The Journal of Clinical Investigation. 122: 1246-61. PMID 22426214 DOI: 10.1172/JCI61135  1
2012 Fernandes KA, Harder JM, Fornarola LB, Freeman RS, Clark AF, Pang IH, John SW, Libby RT. JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death. Neurobiology of Disease. 46: 393-401. PMID 22353563 DOI: 10.1016/j.nbd.2012.02.003  1
2011 Howell GR, Walton DO, King BL, Libby RT, John SW. Datgan, a reusable software system for facile interrogation and visualization of complex transcription profiling data. Bmc Genomics. 12: 429. PMID 21864367 DOI: 10.1186/1471-2164-12-429  1
2011 Harder JM, Libby RT. BBC3 (PUMA) regulates developmental apoptosis but not axonal injury induced death in the retina. Molecular Neurodegeneration. 6: 50. PMID 21762490 DOI: 10.1186/1750-1326-6-50  1
2011 Xi X, McMillan DH, Lehmann GM, Sime PJ, Libby RT, Huxlin KR, Feldon SE, Phipps RP. Ocular fibroblast diversity: implications for inflammation and ocular wound healing. Investigative Ophthalmology & Visual Science. 52: 4859-65. PMID 21571679 DOI: 10.1167/iovs.10-7066  1
2011 Lopes VS, Gibbs D, Libby RT, Aleman TS, Welch DL, Lillo C, Jacobson SG, Radu RA, Steel KP, Williams DS. The Usher 1B protein, MYO7A, is required for normal localization and function of the visual retinoid cycle enzyme, RPE65. Human Molecular Genetics. 20: 2560-70. PMID 21493626 DOI: 10.1093/hmg/ddr155  1
2011 Geng Y, Schery LA, Sharma R, Dubra A, Ahmad K, Libby RT, Williams DR. Optical properties of the mouse eye. Biomedical Optics Express. 2: 717-38. PMID 21483598 DOI: 10.1364/BOE.2.000717  1
2011 Howell GR, Macalinao DG, Sousa GL, Walden M, Soto I, Kneeland SC, Barbay JM, King BL, Marchant JK, Hibbs M, Stevens B, Barres BA, Clark AF, Libby RT, John SW. Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma. The Journal of Clinical Investigation. 121: 1429-44. PMID 21383504 DOI: 10.1172/JCI44646  1
2011 Yin L, Greenberg K, Hunter JJ, Dalkara D, Kolstad KD, Masella BD, Wolfe R, Visel M, Stone D, Libby RT, Diloreto D, Schaffer D, Flannery J, Williams DR, Merigan WH. Intravitreal injection of AAV2 transduces macaque inner retina. Investigative Ophthalmology & Visual Science. 52: 2775-83. PMID 21310920 DOI: 10.1167/iovs.10-6250  1
2010 Feng L, Xie ZH, Ding Q, Xie X, Libby RT, Gan L. MATH5 controls the acquisition of multiple retinal cell fates. Molecular Brain. 3: 36. PMID 21087508 DOI: 10.1186/1756-6606-3-36  1
2010 Libby RT, Gould DB. Endoplasmic reticulum stress as a primary pathogenic mechanism leading to age-related macular degeneration. Advances in Experimental Medicine and Biology. 664: 403-9. PMID 20238041 DOI: 10.1007/978-1-4419-1399-9_46  1
2009 Bertram KM, Baglole CJ, Phipps RP, Libby RT. Molecular regulation of cigarette smoke induced-oxidative stress in human retinal pigment epithelial cells: implications for age-related macular degeneration. American Journal of Physiology. Cell Physiology. 297: C1200-10. PMID 19759330 DOI: 10.1152/ajpcell.00126.2009  1
2009 Scoles D, Gray DC, Hunter JJ, Wolfe R, Gee BP, Geng Y, Masella BD, Libby RT, Russell S, Williams DR, Merigan WH. In-vivo imaging of retinal nerve fiber layer vasculature: imaging histology comparison. Bmc Ophthalmology. 9: 9. PMID 19698151 DOI: 10.1186/1471-2415-9-9  1
2009 Ding Q, Chen H, Xie X, Libby RT, Tian N, Gan L. BARHL2 differentially regulates the development of retinal amacrine and ganglion neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 3992-4003. PMID 19339595 DOI: 10.1523/JNEUROSCI.5237-08.2009  1
2008 Howell GR, Libby RT, John SW. Mouse genetic models: an ideal system for understanding glaucomatous neurodegeneration and neuroprotection. Progress in Brain Research. 173: 303-21. PMID 18929118 DOI: 10.1016/S0079-6123(08)01122-9  1
2007 Howell GR, Libby RT, Jakobs TC, Smith RS, Phalan FC, Barter JW, Barbay JM, Marchant JK, Mahesh N, Porciatti V, Whitmore AV, Masland RH, John SW. Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma. The Journal of Cell Biology. 179: 1523-37. PMID 18158332 DOI: 10.1083/jcb.200706181  1
2007 Libby RT, Howell GR, Pang IH, Savinova OV, Mehalow AK, Barter JW, Smith RS, Clark AF, John SW. Inducible nitric oxide synthase, Nos2, does not mediate optic neuropathy and retinopathy in the DBA/2J glaucoma model. Bmc Neuroscience. 8: 108. PMID 18093296 DOI: 10.1186/1471-2202-8-108  1
2007 Howell GR, Libby RT, Marchant JK, Wilson LA, Cosma IM, Smith RS, Anderson MG, John SW. Absence of glaucoma in DBA/2J mice homozygous for wild-type versions of Gpnmb and Tyrp1. Bmc Genetics. 8: 45. PMID 17608931 DOI: 10.1186/1471-2156-8-45  1
2006 Anderson MG, Libby RT, Mao M, Cosma IM, Wilson LA, Smith RS, John SW. Genetic context determines susceptibility to intraocular pressure elevation in a mouse pigmentary glaucoma. Bmc Biology. 4: 20. PMID 16827931 DOI: 10.1186/1741-7007-4-20  1
2005 Libby RT, Anderson MG, Pang IH, Robinson ZH, Savinova OV, Cosma IM, Snow A, Wilson LA, Smith RS, Clark AF, John SW. Inherited glaucoma in DBA/2J mice: pertinent disease features for studying the neurodegeneration. Visual Neuroscience. 22: 637-48. PMID 16332275 DOI: 10.1017/S0952523805225130  1
2005 Jakobs TC, Libby RT, Ben Y, John SW, Masland RH. Retinal ganglion cell degeneration is topological but not cell type specific in DBA/2J mice. The Journal of Cell Biology. 171: 313-25. PMID 16247030 DOI: 10.1083/jcb.200506099  1
2005 Libby RT, Gould DB, Anderson MG, John SW. Complex genetics of glaucoma susceptibility. Annual Review of Genomics and Human Genetics. 6: 15-44. PMID 16124852 DOI: 10.1146/annurev.genom.6.080604.162209  1
2005 Libby RT, Li Y, Savinova OV, Barter J, Smith RS, Nickells RW, John SW. Susceptibility to neurodegeneration in a glaucoma is modified by Bax gene dosage. Plos Genetics. 1: 17-26. PMID 16103918 DOI: 10.1371/journal.pgen.0010004  1
2005 Kitamoto J, Libby RT, Gibbs D, Steel KP, Williams DS. Myosin VI is required for normal retinal function. Experimental Eye Research. 81: 116-20. PMID 15978262 DOI: 10.1016/j.exer.2005.02.014  1
2005 Whitmore AV, Libby RT, John SW. Glaucoma: thinking in new ways-a rôle for autonomous axonal self-destruction and other compartmentalised processes? Progress in Retinal and Eye Research. 24: 639-62. PMID 15953750 DOI: 10.1016/j.preteyeres.2005.04.004  1
2005 Anderson MG, Libby RT, Gould DB, Smith RS, John SW. High-dose radiation with bone marrow transfer prevents neurodegeneration in an inherited glaucoma. Proceedings of the National Academy of Sciences of the United States of America. 102: 4566-71. PMID 15758074 DOI: 10.1073/pnas.0407357102  1
2004 Gibbs D, Azarian SM, Lillo C, Kitamoto J, Klomp AE, Steel KP, Libby RT, Williams DS. Role of myosin VIIa and Rab27a in the motility and localization of RPE melanosomes. Journal of Cell Science. 117: 6473-83. PMID 15572405 DOI: 10.1242/jcs.01580  1
2004 Libby RT, Lillo C, Kitamoto J, Williams DS, Steel KP. Myosin Va is required for normal photoreceptor synaptic activity. Journal of Cell Science. 117: 4509-15. PMID 15316067 DOI: 10.1242/jcs.01316  1
2003 Libby RT, Kitamoto J, Holme RH, Williams DS, Steel KP. Cdh23 mutations in the mouse are associated with retinal dysfunction but not retinal degeneration. Experimental Eye Research. 77: 731-9. PMID 14609561 DOI: 10.1016/j.exer.2003.07.007  1
2003 Libby RT, Smith RS, Savinova OV, Zabaleta A, Martin JE, Gonzalez FJ, John SW. Modification of ocular defects in mouse developmental glaucoma models by tyrosinase. Science (New York, N.Y.). 299: 1578-81. PMID 12624268 DOI: 10.1126/science.1080095  1
2003 Warner CL, Stewart A, Luzio JP, Steel KP, Libby RT, Kendrick-Jones J, Buss F. Loss of myosin VI reduces secretion and the size of the Golgi in fibroblasts from Snell's waltzer mice. The Embo Journal. 22: 569-79. PMID 12554657 DOI: 10.1093/emboj/cdg055  1
2002 Kros CJ, Marcotti W, van Netten SM, Self TJ, Libby RT, Brown SD, Richardson GP, Steel KP. Reduced climbing and increased slipping adaptation in cochlear hair cells of mice with Myo7a mutations. Nature Neuroscience. 5: 41-7. PMID 11753415 DOI: 10.1038/nn784  1
2001 Libby RT, Steel KP. Electroretinographic anomalies in mice with mutations in Myo7a, the gene involved in human Usher syndrome type 1B. Investigative Ophthalmology & Visual Science. 42: 770-8. PMID 11222540  1
2000 Libby RT, Steel KP. The roles of unconventional myosins in hearing and deafness. Essays in Biochemistry. 35: 159-74. PMID 12471897  1
2000 Libby RT, Champliaud MF, Claudepierre T, Xu Y, Gibbons EP, Koch M, Burgeson RE, Hunter DD, Brunken WJ. Laminin expression in adult and developing retinae: evidence of two novel CNS laminins. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 6517-28. PMID 10964957  1
2000 Libby RT, Brunken WJ, Hunter DD. Roles of the extracellular matrix in retinal development and maintenance. Results and Problems in Cell Differentiation. 31: 115-40. PMID 10929404  1
1999 Libby RT, Lavallee CR, Balkema GW, Brunken WJ, Hunter DD. Disruption of laminin beta2 chain production causes alterations in morphology and function in the CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 9399-411. PMID 10531444  1
1997 Libby RT, Xu Y, Selfors LM, Brunken WJ, Hunter DD. Identification of the cellular source of laminin beta2 in adult and developing vertebrate retinae. The Journal of Comparative Neurology. 389: 655-67. PMID 9421145 DOI: 10.1002/(SICI)1096-9861(19971229)389:4<655::AID-CNE8>3.0.CO;2-#  1
1997 Libby RT, Xu Y, Gibbons EP, Hunter DD, Brunken WJ. Identification and localization of laminin chains in human retina Investigative Ophthalmology and Visual Science. 38: S30.  1
1996 Libby RT, Hunter DD, Brunken WJ. Developmental expression of laminin beta 2 in rat retina. Further support for a role in rod morphogenesis. Investigative Ophthalmology & Visual Science. 37: 1651-61. PMID 8675409  1
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