Trevor Owens - Publications

McGill University, Montreal, QC, Canada 
Immunology, Neuroscience Biology, Pathology

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Khorooshi R, Asgari N, Mørch MT, Berg CT, Owens T. Hypersensitivity Responses in the Central Nervous System. Frontiers in Immunology. 6: 517. PMID 26500654 DOI: 10.3389/Fimmu.2015.00517  1
2015 Wlodarczyk A, Cédile O, Jensen KN, Jasson A, Mony JT, Khorooshi R, Owens T. Pathologic and Protective Roles for Microglial Subsets and Bone Marrow- and Blood-Derived Myeloid Cells in Central Nervous System Inflammation. Frontiers in Immunology. 6: 463. PMID 26441968 DOI: 10.3389/Fimmu.2015.00463  1
2015 Khorooshi R, Mørch MT, Holm TH, Berg CT, Dieu RT, Dræby D, Issazadeh-Navikas S, Weiss S, Lienenklaus S, Owens T. Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis. Acta Neuropathologica. 130: 107-18. PMID 25869642 DOI: 10.1007/S00401-015-1418-Z  1
2015 Cédile O, Løbner M, Toft-Hansen H, Frank I, Wlodarczyk A, Irla M, Owens T. Thymic CCL2 influences induction of T-cell tolerance Journal of Autoimmunity. 55: 73-85. PMID 25129504 DOI: 10.1016/J.Jaut.2014.07.004  1
2014 Mony JT, Khorooshi R, Owens T. Chemokine receptor expression by inflammatory T cells in EAE. Frontiers in Cellular Neuroscience. 8: 187. PMID 25071447 DOI: 10.3389/Fncel.2014.00187  1
2014 Owens T. The complex immunology of multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 20: 1023-1024. PMID 24948791 DOI: 10.1177/1352458514521312  1
2014 Wlodarczyk A, Løbner M, Cédile O, Owens T. Comparison of microglia and infiltrating CD11c⁺ cells as antigen presenting cells for T cell proliferation and cytokine response. Journal of Neuroinflammation. 11: 57. PMID 24666681 DOI: 10.1186/1742-2094-11-57  1
2014 Biber K, Owens T, Boddeke E. What is microglia neurotoxicity (Not)? Glia. 62: 841-54. PMID 24590682 DOI: 10.1002/Glia.22654  1
2014 Owens T, Khorooshi R, Wlodarczyk A, Asgari N. Interferons in the central nervous system: a few instruments play many tunes. Glia. 62: 339-55. PMID 24588027 DOI: 10.1002/Glia.22608  1
2014 Mony JT, Khorooshi R, Owens T. MOG extracellular domain (p1-125) triggers elevated frequency of CXCR3+ CD4+ Th1 cells in the CNS of mice and induces greater incidence of severe EAE. Multiple Sclerosis (Houndmills, Basingstoke, England). 20: 1312-21. PMID 24552747 DOI: 10.1177/1352458514524086  1
2013 Owens T. A wonderful week of immunology in Copenhagen. Scandinavian Journal of Immunology. 77: 223. PMID 23527991 DOI: 10.1111/Sji.12037  1
2013 Khorooshi R, Wlodarczyk A, Asgari N, Owens T. Neuromyelitis optica-like pathology is dependent on type I interferon response. Experimental Neurology. 247: 744-7. PMID 23434493 DOI: 10.1016/J.Expneurol.2013.02.005  1
2013 Khorooshi R, Owens T. Detection and cellular localization of phospho-STAT2 in the central nervous system by immunohistochemical staining. Methods in Molecular Biology (Clifton, N.J.). 967: 179-88. PMID 23296730 DOI: 10.1007/978-1-62703-242-1_13  1
2013 Asgari N, Khorooshi R, Lillevang ST, Owens T. Complement-dependent pathogenicity of brain-specific antibodies in cerebrospinal fluid. Journal of Neuroimmunology. 254: 76-82. PMID 23031833 DOI: 10.1016/J.Jneuroim.2012.09.010  1
2013 Maiorino C, Khorooshi R, Ruffini F, Løbner M, Bergami A, Garzetti L, Martino G, Owens T, Furlan R. Lentiviral-mediated administration of IL-25 in the CNS induces alternative activation of microglia Gene Therapy. 20: 487-496. PMID 22855093 DOI: 10.1038/Gt.2012.58  1
2012 Schellenberg AE, Buist R, Del Bigio MR, Toft-Hansen H, Khorooshi R, Owens T, Peeling J. Blood-brain barrier disruption in CCL2 transgenic mice during pertussis toxin-induced brain inflammation. Fluids and Barriers of the Cns. 9: 10. PMID 22546091 DOI: 10.1186/2045-8118-9-10  1
2012 Stidsen JV, Khorooshi R, Rahbek MK, Kirketerp-Møller KL, Hansen PB, Bie P, Kejling K, Mandrup S, Hawgood S, Nielsen O, Nielsen CH, Owens T, Holmskov U, Sørensen GL. Surfactant protein d deficiency in mice is associated with hyperphagia, altered fat deposition, insulin resistance, and increased basal endotoxemia. Plos One. 7: e35066. PMID 22509382 DOI: 10.1371/Journal.Pone.0035066  1
2012 Reinert LS, Harder L, Holm CK, Iversen MB, Horan KA, Dagnæs-Hansen F, Ulhøi BP, Holm TH, Mogensen TH, Owens T, Nyengaard JR, Thomsen AR, Paludan SR. TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice. The Journal of Clinical Investigation. 122: 1368-76. PMID 22426207 DOI: 10.1172/Jci60893  1
2012 Holm TH, Draeby D, Owens T. Microglia are required for astroglial Toll-like receptor 4 response and for optimal TLR2 and TLR3 response. Glia. 60: 630-8. PMID 22271465 DOI: 10.1002/Glia.22296  1
2011 Füchtbauer L, Groth-Rasmussen M, Holm TH, Løbner M, Toft-Hansen H, Khorooshi R, Owens T. Angiotensin II Type 1 receptor (AT1) signaling in astrocytes regulates synaptic degeneration-induced leukocyte entry to the central nervous system. Brain, Behavior, and Immunity. 25: 897-904. PMID 20868737 DOI: 10.1016/J.Bbi.2010.09.015  1
2009 Miron VE, Zehntner SP, Kuhlmann T, Ludwin SK, Owens T, Kennedy TE, Bedell BJ, Antel JP. Statin therapy inhibits remyelination in the central nervous system. The American Journal of Pathology. 174: 1880-90. PMID 19349355 DOI: 10.2353/Ajpath.2009.080947  1
2008 Owens T, Bechmann I, Engelhardt B. Perivascular spaces and the two steps to neuroinflammation. Journal of Neuropathology and Experimental Neurology. 67: 1113-21. PMID 19018243 DOI: 10.1097/Nen.0B013E31818F9Ca8  1
2008 Fux M, van Rooijen N, Owens T. Macrophage-independent T cell infiltration to the site of injury-induced brain inflammation. Journal of Neuroimmunology. 203: 64-72. PMID 18653241 DOI: 10.1016/J.Jneuroim.2008.06.025  0.32
2007 Zehntner SP, Bourbonnière L, Moore CS, Morris SJ, Methot D, St Jean M, Lacasse E, Hebb AL, Robertson GS, Durkin J, Gillard JW, Owens T. X-linked inhibitor of apoptosis regulates T cell effector function. Journal of Immunology (Baltimore, Md. : 1950). 179: 7553-60. PMID 18025200 DOI: 10.4049/Jimmunol.179.11.7553  1
2006 Babcock AA, Wirenfeldt M, Holm T, Nielsen HH, Dissing-Olesen L, Toft-Hansen H, Millward JM, Landmann R, Rivest S, Finsen B, Owens T. Toll-like receptor 2 signaling in response to brain injury: an innate bridge to neuroinflammation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 12826-37. PMID 17151286 DOI: 10.1523/Jneurosci.4937-05.2006  1
2006 Kuhlmann T, Remington L, Cognet I, Bourbonniere L, Zehntner S, Guilhot F, Herman A, Guay-Giroux A, Antel JP, Owens T, Gauchat JF. Continued administration of ciliary neurotrophic factor protects mice from inflammatory pathology in experimental autoimmune encephalomyelitis. The American Journal of Pathology. 169: 584-98. PMID 16877358 DOI: 10.2353/Ajpath.2006.051086  0.48
2006 Moore CS, Earl N, Frenette R, Styhler A, Mancini JA, Nicholson DW, Hebb AL, Owens T, Robertson GS. Peripheral phosphodiesterase 4 inhibition produced by 4-[2-(3,4-Bis-difluoromethoxyphenyl)-2-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl]-3-methylpyridine-1-oxide (L-826,141) prevents experimental autoimmune encephalomyelitis. The Journal of Pharmacology and Experimental Therapeutics. 319: 63-72. PMID 16809479 DOI: 10.1124/Jpet.106.106096  1
2006 Wheeler RD, Zehntner SP, Kelly LM, Bourbonnière L, Owens T. Elevated interferon gamma expression in the central nervous system of tumour necrosis factor receptor 1-deficient mice with experimental autoimmune encephalomyelitis. Immunology. 118: 527-38. PMID 16780563 DOI: 10.1111/J.1365-2567.2006.02395.X  1
2006 Hollmann CA, Owens T, Nalbantoglu J, Hudson TJ, Sladek R. Constitutive activation of extracellular signal-regulated kinase predisposes diffuse large B-cell lymphoma cell lines to CD40-mediated cell death. Cancer Research. 66: 3550-7. PMID 16585179 DOI: 10.1158/0008-5472.Can-05-2498  1
2006 Monsonego A, Imitola J, Petrovic S, Zota V, Nemirovsky A, Baron R, Fisher Y, Owens T, Weiner HL. Abeta-induced meningoencephalitis is IFN-gamma-dependent and is associated with T cell-dependent clearance of Abeta in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 103: 5048-53. PMID 16549802 DOI: 10.1073/Pnas.0506209103  1
2005 Zehntner SP, Brickman C, Bourbonnière L, Remington L, Caruso M, Owens T. Neutrophils that infiltrate the central nervous system regulate T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 174: 5124-31. PMID 15814744 DOI: 10.4049/Jimmunol.174.8.5124  1
2004 Toft-Hansen H, Nuttall RK, Edwards DR, Owens T. Key metalloproteinases are expressed by specific cell types in experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 173: 5209-18. PMID 15470066 DOI: 10.4049/Jimmunol.173.8.5209  1
2004 Zehntner SP, Bourbonniere L, Hassan-Zahraee M, Tran E, Owens T. Bone marrow-derived versus parenchymal sources of inducible nitric oxide synthase in experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. 150: 70-9. PMID 15081250 DOI: 10.1016/J.Jneuroim.2004.01.020  1
2003 Babcock AA, Kuziel WA, Rivest S, Owens T. Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7922-30. PMID 12944523 DOI: 10.1523/Jneurosci.23-21-07922.2003  1
2001 Owens T, Wekerle H, Antel J. Genetic models for CNS inflammation. Nature Medicine. 7: 161-6. PMID 11175845 DOI: 10.1038/84603  1
2001 Owens T, Tran EH, Hassan-Zahraee M, Babcock A, Krakowski ML, Fournier S, Jensen MB, Finsen B. The pathogenesis of encephalitis Neuroimmune Biology. 1: 387-397. DOI: 10.1016/S1567-7443(01)80035-1  1
2000 Hassan-Zahraee M, Tran EH, Bourbonnière L, Owens T. Elevated interferon-gamma in CNS inflammatory disease: a potential complication for bone marrow reconstitution in MS. Journal of Neuroimmunology. 108: 40-4. PMID 10900335 DOI: 10.1016/S0165-5728(99)00263-5  1
2000 Tran EH, Kuziel WA, Owens T. Induction of experimental autoimmune encephalomyelitis in C57BL/6 mice deficient in either the chemokine macrophage inflammatory protein-1alpha or its CCR5 receptor. European Journal of Immunology. 30: 1410-5. PMID 10820388 DOI: 10.1002/(Sici)1521-4141(200005)30:5<1410::Aid-Immu1410>3.0.Co;2-L  1
2000 Krakowski ML, Owens T. Naive T lymphocytes traffic to inflamed central nervous system, but require antigen recognition for activation European Journal of Immunology. 30: 1002-1009. PMID 10760787 DOI: 10.1002/(Sici)1521-4141(200004)30:4<1002::Aid-Immu1002>3.0.Co;2-2  1
2000 Tran EH, Prince EN, Owens T. IFN-gamma shapes immune invasion of the central nervous system via regulation of chemokines. Journal of Immunology (Baltimore, Md. : 1950). 164: 2759-68. PMID 10679118 DOI: 10.4049/Jimmunol.164.5.2759  1
2000 Hassan-Zahraee M, Ladiwala U, Lavoie PM, McCrea E, Sekaly RP, Owens T, Antel JP. Superantigen presenting capacity of human astrocytes Journal of Neuroimmunology. 102: 131-136. PMID 10636481 DOI: 10.1016/S0165-5728(99)00174-5  1
1999 Glabinski AR, Krakowski M, Han Y, Owens T, Ransohoff RM. Chemokine expression in GKO mice (lacking interferon-gamma) with experimental autoimmune encephalomyelitis Journal of Neurovirology. 5: 95-101. PMID 10190695 DOI: 10.3109/13550289909029750  1
1998 Chagnon F, Lamarre A, Lachance C, Krakowski M, Owens T, Laliberté JF, Talbot PJ. Characterization of the expression and immunogenicity of the ns4b protein of human coronavirus 229E. Canadian Journal of Microbiology. 44: 1012-7. PMID 9933919 DOI: 10.1139/Cjm-44-10-1012  1
1998 Owens T, Tran E, Hassan-Zahraee M, Krakowski M. Immune cell entry to the CNS - A focus for immunoregulation of EAE Research in Immunology. 149. PMID 9923633 DOI: 10.1016/S0923-2494(99)80005-4  1
1998 Renno T, Taupin V, Bourbonnière L, Verge G, Tran E, De Simone R, Krakowski M, Rodriguez M, Peterson A, Owens T. Interferon-gamma in progression to chronic demyelination and neurological deficit following acute EAE. Molecular and Cellular Neurosciences. 12: 376-89. PMID 9888990 DOI: 10.1006/Mcne.1998.0725  1
1998 Tran EH, Hoekstra K, van Rooijen N, Dijkstra CD, Owens T. Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice. Journal of Immunology (Baltimore, Md. : 1950). 161: 3767-75. PMID 9759903  1
1998 Becher B, Owens T, Antel JP, Barker PA. CD95-CD95L: Can the brain learn from the immune system? Trends in Neurosciences. 21: 114-117. PMID 9530918 DOI: 10.1016/S0166-2236(97)01180-6  1
1997 Krakowski ML, Owens T. The central nervous system environment controls effector CD4+ T cell cytokine profile in experimental allergic encephalomyelitis European Journal of Immunology. 27: 2840-2847. PMID 9394808 DOI: 10.1002/Eji.1830271115  1
1997 Hardin-Pouzet H, Krakowski M, Bourbonnière L, Didier-Bazes M, Tran E, Owens T. Glutamate metabolism is down-regulated in astrocytes during experimental allergic encephalomyelitis Glia. 20: 79-85. PMID 9145307 DOI: 10.1002/(Sici)1098-1136(199705)20:1<79::Aid-Glia8>3.0.Co;2-0  1
1997 Tran EH, Hardin-Pouzet H, Verge G, Owens T. Astrocytes and microglia express inducible nitric oxide synthase in mice with experimental allergic encephalomyelitis. Journal of Neuroimmunology. 74: 121-9. PMID 9119964 DOI: 10.1016/S0165-5728(96)00215-9  1
1996 Krakowski M, Owens T. Interferon-γ confers resistance to experimental allergic encephalomyelitis European Journal of Immunology. 26: 1641-1646. PMID 8766573 DOI: 10.1002/Eji.1830260735  1
1989 Williamson DJ, Owens T, Pearse M. Detection of colony-stimulating factor messenger RNA in single T cells by in situ hybridization. Journal of Cellular Physiology. 139: 245-52. PMID 2785523 DOI: 10.1002/Jcp.1041390205  1
1984 Owens T, Czitrom AA, Gascoigne NR, Crispe IN, Ratcliffe MJ, Lai PK, Mitchison NA. The presentation of cell surface alloantigens to T cells. Immunobiology. 168: 189-201. PMID 6241598 DOI: 10.1016/S0171-2985(84)80110-2  1
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