Laura Cancedda - Publications

Affiliations: 
Neuroscience and Brain Technologies Italian Institute of Technology, Genoa, United States 

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Cwetsch AW, Ziogas I, Narducci R, Savardi A, Bolla M, Pinto B, Perlini LE, Bassani S, Passafaro M, Cancedda L. A rat model of a focal mosaic expression of PCDH19 replicates human brain developmental abnormalities and behaviours. Brain Communications. 4: fcac091. PMID 35528232 DOI: 10.1093/braincomms/fcac091  0.768
2021 Parrini M, Naskar S, Alberti M, Colombi I, Morelli G, Rocchi A, Nanni M, Piccardi F, Charles S, Ronzitti G, Mingozzi F, Contestabile A, Cancedda L. Restoring neuronal chloride homeostasis with anti-NKCC1 gene therapy rescues cognitive deficits in a mouse model of Down syndrome. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 34058387 DOI: 10.1016/j.ymthe.2021.05.023  0.807
2020 Pinto B, Morelli G, Rastogi M, Savardi A, Fumagalli A, Petretto A, Bartolucci M, Varea E, Catelani T, Contestabile A, Perlini LE, Cancedda L. Rescuing Over-activated Microglia Restores Cognitive Performance in Juvenile Animals of the Dp(16) Mouse Model of Down Syndrome. Neuron. PMID 33027640 DOI: 10.1016/j.neuron.2020.09.010  0.779
2020 Savardi A, Borgogno M, Narducci R, La Sala G, Ortega JA, Summa M, Armirotti A, Bertorelli R, Contestabile A, De Vivo M, Cancedda L. Discovery of a Small Molecule Drug Candidate for Selective NKCC1 Inhibition in Brain Disorders. Chem. 6: 2073-2096. PMID 32818158 DOI: 10.1016/J.Chempr.2020.06.017  0.315
2020 Szczurkowska J, Lee SI, Guo A, Cwetsch AW, Khan T, Rao S, Walz G, Huber TB, Cancedda L, Pautot S, Shelly M. A Localized Scaffold for cGMP Increase Is Required for Apical Dendrite Development. Cell Reports. 31: 107519. PMID 32294442 DOI: 10.1016/J.Celrep.2020.03.083  0.62
2019 Vagni P, Perlini LE, Chenais NAL, Marchetti T, Parrini M, Contestabile A, Cancedda L, Ghezzi D. Gene Editing Preserves Visual Functions in a Mouse Model of Retinal Degeneration. Frontiers in Neuroscience. 13: 945. PMID 31551698 DOI: 10.3389/Fnins.2019.00945  0.753
2019 Costa RO, Martins H, Martins LF, Cwetsch AW, Mele M, Pedro JR, Tomé D, Jeon NL, Cancedda L, Jaffrey SR, Almeida RD. Synaptogenesis Stimulates a Proteasome-Mediated Ribosome Reduction in Axons. Cell Reports. 28: 864-876.e6. PMID 31340150 DOI: 10.1016/J.Celrep.2019.06.080  0.328
2019 Naskar S, Narducci R, Balzani E, Cwetsch AW, Tucci V, Cancedda L. The development of synaptic transmission is time-locked to early social behaviors in rats. Nature Communications. 10: 1195. PMID 30867422 DOI: 10.1038/S41467-019-09156-3  0.787
2019 Onesto V, Villani M, Narducci R, Malara N, Imbrogno A, Allione M, Costa N, Coppedè N, Zappettini A, Cannistraci CV, Cancedda L, Amato F, DI Fabrizio E, Gentile F. Cortical-like mini-columns of neuronal cells on zinc oxide nanowire surfaces. Scientific Reports. 9: 4021. PMID 30858456 DOI: 10.1038/S41598-019-40548-Z  0.349
2018 Awad PN, Amegandjin CA, Szczurkowska J, Carriço JN, Fernandes do Nascimento AS, Baho E, Chattopadhyaya B, Cancedda L, Carmant L, Di Cristo G. KCC2 Regulates Dendritic Spine Formation in a Brain-Region Specific and BDNF Dependent Manner. Cerebral Cortex (New York, N.Y. : 1991). PMID 30169756 DOI: 10.1093/Cercor/Bhy198  0.742
2018 Szczurkowska J, Pischedda F, Pinto B, Managò F, Haas CA, Summa M, Bertorelli R, Papaleo F, Schäfer MK, Piccoli G, Cancedda L. NEGR1 and FGFR2 cooperatively regulate cortical development and core behaviours related to autism disorders in mice. Brain : a Journal of Neurology. PMID 30059965 DOI: 10.1093/Brain/Awy190  0.349
2018 Cwetsch AW, Pinto B, Savardi A, Cancedda L. In vivo methods for acute modulation of gene expression in the central nervous system. Progress in Neurobiology. PMID 29694844 DOI: 10.1016/J.Pneurobio.2018.04.008  0.316
2018 Bassani S, Cwetsch AW, Gerosa L, Serratto GM, Folci A, Hall IF, Mazzanti M, Cancedda L, Passafaro M. The female epilepsy protein PCDH19 is a new GABAAR binding partner that regulates GABAergic transmission as well as migration and morphological maturation of hippocampal neurons. Human Molecular Genetics. PMID 29360992 DOI: 10.1093/Hmg/Ddy019  0.436
2017 Parrini M, Ghezzi D, Deidda G, Medrihan L, Castroflorio E, Alberti M, Baldelli P, Cancedda L, Contestabile A. Aerobic exercise and a BDNF-mimetic therapy rescue learning and memory in a mouse model of Down syndrome. Scientific Reports. 7: 16825. PMID 29203796 DOI: 10.1038/S41598-017-17201-8  0.765
2017 Gobbo F, Marchetti L, Jacob A, Pinto B, Binini N, Pecoraro Bisogni F, Alia C, Luin S, Caleo M, Fellin T, Cancedda L, Cattaneo A. Activity-dependent expression of Channelrhodopsin at neuronal synapses. Nature Communications. 8: 1629. PMID 29158498 DOI: 10.1038/S41467-017-01699-7  0.701
2017 Keshavan S, Naskar S, Diaspro A, Cancedda L, Dante S. Developmental refinement of synaptic transmission on micropatterned single layer graphene. Acta Biomaterialia. PMID 29122711 DOI: 10.1016/J.Actbio.2017.11.005  0.781
2017 Sulis Sato S, Artoni P, Landi S, Cozzolino O, Parra R, Pracucci E, Trovato F, Szczurkowska J, Luin S, Arosio D, Beltram F, Cancedda L, Kaila K, Ratto GM. Simultaneous two-photon imaging of intracellular chloride concentration and pH in mouse pyramidal neurons in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 28973889 DOI: 10.1073/Pnas.1702861114  0.362
2017 Contestabile A, Magara S, Cancedda L. The GABAergic Hypothesis for Cognitive Disabilities in Down Syndrome. Frontiers in Cellular Neuroscience. 11: 54. PMID 28326014 DOI: 10.3389/Fncel.2017.00054  0.426
2016 Perlini LE, Benfenati F, Cancedda L. Synapsin III in brain development. Oncotarget. PMID 26993596 DOI: 10.18632/Oncotarget.8106  0.795
2016 Baroncelli L, Cenni MC, Melani R, Deidda G, Landi S, Narducci R, Cancedda L, Maffei L, Berardi N. Early IGF-1 Primes Visual Cortex Maturation And Accelerates Developmental Switch Between NKCC1 and KCC2 Chloride Transporters in Enriched Animals. Neuropharmacology. PMID 26924708 DOI: 10.1016/J.Neuropharm.2016.02.034  0.786
2016 Awad PN, Sanon NT, Chattopadhyaya B, Carriço JN, Ouardouz M, Gagné J, Duss S, Wolf D, Desgent S, Cancedda L, Carmant L, Di Cristo G. Reducing premature KCC2 expression rescues seizure susceptibility and spine morphology in atypical febrile seizures. Neurobiology of Disease. PMID 26875662 DOI: 10.1016/J.Nbd.2016.02.014  0.696
2016 Szczurkowska J, Cwetsch AW, Dal Maschio M, Ghezzi D, Ratto GM, Cancedda L. Targeted in vivo genetic manipulation of the mouse or rat brain by in utero electroporation with a triple-electrode probe. Nature Protocols. 11: 399-412. PMID 26844428 DOI: 10.1038/Nprot.2016.014  0.323
2016 Contestabile A, Parrini M, Naskar S, Alberti M, Rocchi A, Nanni M, Ronzitti G, Mingozzi F, Cancedda L. 53. A Neuro-Specific Gene Therapy Approach to Treat Cognitive Impairment in Down Syndrome by RNA Interference Molecular Therapy. 24: S23-S24. DOI: 10.1016/S1525-0016(16)32862-3  0.807
2016 Keshavan S, Naskar S, Diaspro A, Cancedda L, Dante S. Electrophysiology of Patterned Neuronal Networks on Monolayer Graphene Biophysical Journal. 110: 41a. DOI: 10.1016/J.Bpj.2015.11.290  0.768
2015 Deidda G, Parrini M, Naskar S, Bozarth IF, Contestabile A, Cancedda L. Excitatory GABAergic transmission impairs synaptic plasticity and memory in Down syndrome. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 47: 36. PMID 26531425 DOI: 10.1016/J.Ijdevneu.2015.04.104  0.763
2015 Awad PN, Chattopadhyaya B, Sanon N, Szczurkowska J, Baho E, Nũnes Carriço J, Ouardouz M, Desgent S, Cancedda L, Carmant L, Di Cristo G. Status epilepticus-induced precocious expression of KCC2 impairs excitatory synapse formation. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 47: 25-6. PMID 26531399 DOI: 10.1016/J.Ijdevneu.2015.04.077  0.697
2015 Szczurkowska J, Pischedda F, Manago F, Haas C, Papaleo F, Schäfer M, Piccoli G, Cancedda L. Negr1 is required for transition of migrating pyramidal neurons from layer V to layer II/III of the mouse cerebral cortex. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 47: 16. PMID 26531375 DOI: 10.1016/J.Ijdevneu.2015.04.053  0.312
2015 Piccini A, Perlini LE, Cancedda L, Benfenati F, Giovedì S. Phosphorylation by PKA and Cdk5 Mediates the Early Effects of Synapsin III in Neuronal Morphological Maturation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 13148-59. PMID 26400944 DOI: 10.1523/Jneurosci.1379-15.2015  0.789
2015 Perlini LE, Szczurkowska J, Ballif BA, Piccini A, Sacchetti S, Giovedì S, Benfenati F, Cancedda L. Synapsin III acts downstream of semaphorin 3A/CDK5 signaling to regulate radial migration and orientation of pyramidal neurons in vivo. Cell Reports. 11: 234-48. PMID 25843720 DOI: 10.1016/J.Celrep.2015.03.022  0.79
2015 Deidda G, Parrini M, Naskar S, Bozarth IF, Contestabile A, Cancedda L. Reversing excitatory GABAAR signaling restores synaptic plasticity and memory in a mouse model of Down syndrome. Nature Medicine. 21: 318-26. PMID 25774849 DOI: 10.1038/Nm.3827  0.779
2015 Deidda G, Allegra M, Cerri C, Naskar S, Bony G, Zunino G, Bozzi Y, Caleo M, Cancedda L. Early depolarizing GABA controls critical-period plasticity in the rat visual cortex. Nature Neuroscience. 18: 87-96. PMID 25485756 DOI: 10.1038/Nn.3890  0.768
2015 Pischedda F, Szczurkowska J, Daniela Cirnaru M, Cancedda L, Piccoli G. The role of Negr1 in cortical development via NCAM-FGFR2 signaling Springerplus. 4. DOI: 10.1186/2193-1801-4-S1-P38  0.432
2014 Deidda G, Bozarth IF, Cancedda L. Modulation of GABAergic transmission in development and neurodevelopmental disorders: investigating physiology and pathology to gain therapeutic perspectives. Frontiers in Cellular Neuroscience. 8: 119. PMID 24904277 DOI: 10.3389/Fncel.2014.00119  0.766
2014 Zuccaro E, Bergami M, Vignoli B, Bony G, Pierchala BA, Santi S, Cancedda L, Canossa M. Polarized expression of p75(NTR) specifies axons during development and adult neurogenesis. Cell Reports. 7: 138-52. PMID 24685135 DOI: 10.1016/J.Celrep.2014.02.039  0.389
2014 Pischedda F, Szczurkowska J, Cirnaru MD, Giesert F, Vezzoli E, Ueffing M, Sala C, Francolini M, Hauck SM, Cancedda L, Piccoli G. A cell surface biotinylation assay to reveal membrane-associated neuronal cues: Negr1 regulates dendritic arborization. Molecular & Cellular Proteomics : McP. 13: 733-48. PMID 24382801 DOI: 10.1074/Mcp.M113.031716  0.389
2013 Bony G, Szczurkowska J, Tamagno I, Shelly M, Contestabile A, Cancedda L. Non-hyperpolarizing GABAB receptor activation regulates neuronal migration and neurite growth and specification by cAMP/LKB1. Nature Communications. 4: 1800. PMID 23653212 DOI: 10.1038/Ncomms2820  0.645
2013 Szczurkowska J, Cwetsch AW, Maschio MD, Ghezzi D, Ratto GM, Cancedda L. High-performance and reliable site-directed in vivo genetic manipulation of mouse and rat brain by in utero electroporation with a triple-electrode probe. Protocol Exchange. DOI: 10.1038/Protex.2013.089  0.352
2012 Ben-Ari Y, Woodin MA, Sernagor E, Cancedda L, Vinay L, Rivera C, Legendre P, Luhmann HJ, Bordey A, Wenner P, Fukuda A, van den Pol AN, Gaiarsa JL, Cherubini E. Refuting the challenges of the developmental shift of polarity of GABA actions: GABA more exciting than ever! Frontiers in Cellular Neuroscience. 6: 35. PMID 22973192 DOI: 10.3389/Fncel.2012.00035  0.675
2012 dal Maschio M, Ghezzi D, Bony G, Alabastri A, Deidda G, Brondi M, Sato SS, Zaccaria RP, Di Fabrizio E, Ratto GM, Cancedda L. High-performance and site-directed in utero electroporation by a triple-electrode probe. Nature Communications. 3: 960. PMID 22805567 DOI: 10.1038/Ncomms1961  0.724
2012 Succol F, Fiumelli H, Benfenati F, Cancedda L, Barberis A. Intracellular chloride concentration influences the GABAA receptor subunit composition. Nature Communications. 3: 738. PMID 22415829 DOI: 10.1038/Ncomms1744  0.358
2011 Di Cristo G, Pizzorusso T, Cancedda L, Sernagor E. GABAergic circuit development and its implication for CNS disorders. Neural Plasticity. 2011: 623705. PMID 22013542 DOI: 10.1155/2011/623705  0.716
2011 Shelly M, Cancedda L, Lim BK, Popescu AT, Cheng PL, Gao H, Poo MM. Semaphorin3A regulates neuronal polarization by suppressing axon formation and promoting dendrite growth. Neuron. 71: 433-46. PMID 21835341 DOI: 10.1016/J.Neuron.2011.06.041  0.772
2010 Sernagor E, Chabrol F, Bony G, Cancedda L. GABAergic control of neurite outgrowth and remodeling during development and adult neurogenesis: general rules and differences in diverse systems. Frontiers in Cellular Neuroscience. 4: 11. PMID 20428495 DOI: 10.3389/Fncel.2010.00011  0.418
2010 Shelly M, Lim BK, Cancedda L, Heilshorn SC, Gao H, Poo MM. Local and long-range reciprocal regulation of cAMP and cGMP in axon/dendrite formation. Science (New York, N.Y.). 327: 547-52. PMID 20110498 DOI: 10.1126/Science.1179735  0.68
2010 Harauzov A, Spolidoro M, DiCristo G, De Pasquale R, Cancedda L, Pizzorusso T, Viegi A, Berardi N, Maffei L. Reducing intracortical inhibition in the adult visual cortex promotes ocular dominance plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 361-71. PMID 20053917 DOI: 10.1523/Jneurosci.2233-09.2010  0.784
2010 Cancedda L, Poo MM. Synapse Formation: Competition and the Role of Activity Encyclopedia of Neuroscience. 697-703. DOI: 10.1016/B978-008045046-9.00354-5  0.468
2007 Cancedda L, Fiumelli H, Chen K, Poo MM. Excitatory GABA action is essential for morphological maturation of cortical neurons in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 5224-35. PMID 17494709 DOI: 10.1523/Jneurosci.5169-06.2007  0.591
2007 Shelly M, Cancedda L, Heilshorn S, Sumbre G, Poo MM. LKB1/STRAD promotes axon initiation during neuronal polarization. Cell. 129: 565-77. PMID 17482549 DOI: 10.1016/J.Cell.2007.04.012  0.773
2007 Putignano E, Lonetti G, Cancedda L, Ratto G, Costa M, Maffei L, Pizzorusso T. Developmental downregulation of histone posttranslational modifications regulates visual cortical plasticity. Neuron. 53: 747-59. PMID 17329213 DOI: 10.1016/J.Neuron.2007.02.007  0.689
2007 Putignano E, Lonetti G, Cancedda L, Ratto G, Costa M, Maffei L, Pizzorusso T. Developmental Downregulation of Histone Posttranslational Modifications Regulates Visual Cortical Plasticity (DOI:10.1016/j.neuron.2007.02.007) Neuron. 54: 177. DOI: 10.1016/j.neuron.2007.03.011  0.682
2005 Fiumelli H, Cancedda L, Poo MM. Modulation of GABAergic transmission by activity via postsynaptic Ca2+-dependent regulation of KCC2 function. Neuron. 48: 773-86. PMID 16337915 DOI: 10.1016/J.Neuron.2005.10.025  0.565
2004 Sale A, Putignano E, Cancedda L, Landi S, Cirulli F, Berardi N, Maffei L. Enriched environment and acceleration of visual system development. Neuropharmacology. 47: 649-60. PMID 15458836 DOI: 10.1016/J.Neuropharm.2004.07.008  0.72
2004 Cancedda L, Putignano E, Sale A, Viegi A, Berardi N, Maffei L. Acceleration of visual system development by environmental enrichment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4840-8. PMID 15152044 DOI: 10.1523/Jneurosci.0845-04.2004  0.732
2003 Cancedda L, Putignano E, Impey S, Maffei L, Ratto GM, Pizzorusso T. Patterned vision causes CRE-mediated gene expression in the visual cortex through PKA and ERK. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7012-20. PMID 12904462 DOI: 10.1523/Jneurosci.23-18-07012.2003  0.698
2002 Bartoletti A, Cancedda L, Reid SW, Tessarollo L, Porciatti V, Pizzorusso T, Maffei L. Heterozygous knock-out mice for brain-derived neurotrophic factor show a pathway-specific impairment of long-term potentiation but normal critical period for monocular deprivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10072-7. PMID 12451106 DOI: 10.1523/Jneurosci.22-23-10072.2002  0.694
2001 Di Cristo G, Berardi N, Cancedda L, Pizzorusso T, Putignano E, Ratto GM, Maffei L. Requirement of ERK activation for visual cortical plasticity. Science (New York, N.Y.). 292: 2337-40. PMID 11423664 DOI: 10.1126/Science.1059075  0.792
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