John A. DeSimone, Ph.D. - Publications

Affiliations: 
Physiology and Biophysics Virginia Commonwealth University, Richmond, VA, United States 
Area:
Taste system, sensory transduction, sodium taste

69/133 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Ramsey IS, DeSimone JA. Otopetrin-1: A sour-tasting proton channel. The Journal of General Physiology. PMID 29483132 DOI: 10.1085/Jgp.201812003  0.317
2017 Qian J, Mummalaneni S, Phan TT, Heck GL, DeSimone JA, West D, Mahavadi S, Hojati D, Murthy KS, Rhyu MR, Spielman AI, Özdener MH, Lyall V. Cyclic-AMP regulates postnatal development of neural and behavioral responses to NaCl in rats. Plos One. 12: e0171335. PMID 28192441 DOI: 10.1371/Journal.Pone.0171335  0.788
2017 DeSimone JA. The dependence of the phasic response of the taste nerves on stimulus flow rate arises in the diffusion boundary layer region at the lingual surface: A convective-diffusion analysis Chemical Engineering Science. 168: 289-308. DOI: 10.1016/J.Ces.2017.04.034  0.355
2015 Ren ZJ, Mummalaneni S, Qian J, Baumgarten CM, DeSimone JA, Lyall V. Nicotinic Acetylcholine Receptor (nAChR) Dependent Chorda Tympani Taste Nerve Responses to Nicotine, Ethanol and Acetylcholine. Plos One. 10: e0127936. PMID 26039516 DOI: 10.1371/Journal.Pone.0127936  0.358
2015 DeSimone JA, Phan TH, Mummalaneni S, Rhyu MR, Heck GL, Lyall V. Regulatory Effects of Ca2+ and H+ on the Rat Chorda Tympani Response to NaCl and KCl. Chemical Senses. 40: 401-12. PMID 25953775 DOI: 10.1093/Chemse/Bjv022  0.792
2014 Kendig DM, Hurst NR, Bradley ZL, Mahavadi S, Kuemmerle JF, Lyall V, DeSimone J, Murthy KS, Grider JR. Activation of the umami taste receptor (T1R1/T1R3) initiates the peristaltic reflex and pellet propulsion in the distal colon. American Journal of Physiology. Gastrointestinal and Liver Physiology. 307: G1100-7. PMID 25324508 DOI: 10.1152/Ajpgi.00251.2014  0.361
2014 Mummalaneni S, Qian J, Phan TH, Rhyu MR, Heck GL, DeSimone JA, Lyall V. Effect of ENaC modulators on rat neural responses to NaCl. Plos One. 9: e98049. PMID 24839965 DOI: 10.1371/Journal.Pone.0098049  0.795
2013 Ren Z, Rhyu MR, Phan TH, Mummalaneni S, Murthy KS, Grider JR, DeSimone JA, Lyall V. TRPM5-dependent amiloride- and benzamil-insensitive NaCl chorda tympani taste nerve response. American Journal of Physiology. Gastrointestinal and Liver Physiology. 305: G106-17. PMID 23639808 DOI: 10.1152/Ajpgi.00053.2013  0.5
2013 Dewis ML, Phan TH, Ren Z, Meng X, Cui M, Mummalaneni S, Rhyu MR, DeSimone JA, Lyall V. N-geranyl cyclopropyl-carboximide modulates salty and umami taste in humans and animal models. Journal of Neurophysiology. 109: 1078-90. PMID 23221408 DOI: 10.1152/Jn.00124.2012  0.471
2012 Desimone JA, Phan TH, Ren Z, Mummalaneni S, Lyall V. Changes in taste receptor cell [Ca2+]i modulate chorda tympani responses to bitter, sweet, and umami taste stimuli. Journal of Neurophysiology. 108: 3221-32. PMID 22993258 DOI: 10.1152/Jn.00129.2012  0.415
2012 Desimone JA, Ren Z, Phan TH, Heck GL, Mummalaneni S, Lyall V. Changes in taste receptor cell [Ca2+]i modulate chorda tympani responses to salty and sour taste stimuli. Journal of Neurophysiology. 108: 3206-20. PMID 22956787 DOI: 10.1152/Jn.00916.2011  0.773
2011 Coleman J, Williams A, Phan TH, Mummalaneni S, Melone P, Ren Z, Zhou H, Mahavadi S, Murthy KS, Katsumata T, DeSimone JA, Lyall V. Strain differences in the neural, behavioral, and molecular correlates of sweet and salty taste in naive, ethanol- and sucrose-exposed P and NP rats. Journal of Neurophysiology. 106: 2606-21. PMID 21849614 DOI: 10.1152/Jn.00196.2010  0.359
2011 DeSimone JA, Phan TH, Heck GL, Ren Z, Coleman J, Mummalaneni S, Melone P, Lyall V. Involvement of NADPH-dependent and cAMP-PKA sensitive H+ channels in the chorda tympani nerve responses to strong acids. Chemical Senses. 36: 389-403. PMID 21339339 DOI: 10.1093/Chemse/Bjq148  0.793
2011 Sturz GR, Phan TH, Mummalaneni S, Ren Z, DeSimone JA, Lyall V. The K+-H+ exchanger, nigericin, modulates taste cell pH and chorda tympani taste nerve responses to acidic stimuli. Chemical Senses. 36: 375-88. PMID 21257734 DOI: 10.1093/Chemse/Bjq146  0.499
2010 Lyall V, Phan TH, Ren Z, Mummalaneni S, Melone P, Mahavadi S, Murthy KS, DeSimone JA. Regulation of the putative TRPV1t salt taste receptor by phosphatidylinositol 4,5-bisphosphate. Journal of Neurophysiology. 103: 1337-49. PMID 20032236 DOI: 10.1152/Jn.00883.2009  0.453
2009 Lyall V, Phan TH, Mummalaneni S, Melone P, Mahavadi S, Murthy KS, DeSimone JA. Regulation of the benzamil-insensitive salt taste receptor by intracellular Ca2+, protein kinase C, and calcineurin. Journal of Neurophysiology. 102: 1591-605. PMID 19553475 DOI: 10.1152/Jn.91301.2008  0.422
2009 Oliveira-Maia AJ, Stapleton-Kotloski JR, Lyall V, Phan TH, Mummalaneni S, Melone P, Desimone JA, Nicolelis MA, Simon SA. Nicotine activates TRPM5-dependent and independent taste pathways. Proceedings of the National Academy of Sciences of the United States of America. 106: 1596-601. PMID 19164511 DOI: 10.1073/Pnas.0810184106  0.352
2008 Katsumata T, Nakakuki H, Tokunaga C, Fujii N, Egi M, Phan TH, Mummalaneni S, DeSimone JA, Lyall V. Effect of Maillard reacted peptides on human salt taste and the amiloride-insensitive salt taste receptor (TRPV1t). Chemical Senses. 33: 665-80. PMID 18603652 DOI: 10.1093/Chemse/Bjn033  0.5
2007 Lyall V, Phan TH, Mummalaneni S, Mansouri M, Heck GL, Kobal G, DeSimone JA. Effect of nicotine on chorda tympani responses to salty and sour stimuli. Journal of Neurophysiology. 98: 1662-74. PMID 17615133 DOI: 10.1152/Jn.00366.2007  0.792
2007 Treesukosol Y, Lyall V, Heck GL, DeSimone JA, Spector AC. A psychophysical and electrophysiological analysis of salt taste in Trpv1 null mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 292: R1799-809. PMID 17234959 DOI: 10.1152/Ajpregu.00587.2006  0.767
2006 DeSimone JA, Lyall V. Taste receptors in the gastrointestinal tract III. Salty and sour taste: sensing of sodium and protons by the tongue. American Journal of Physiology. Gastrointestinal and Liver Physiology. 291: G1005-10. PMID 16809639 DOI: 10.1152/Ajpgi.00235.2006  0.496
2006 Lyall V, Pasley H, Phan TH, Mummalaneni S, Heck GL, Vinnikova AK, DeSimone JA. Intracellular pH modulates taste receptor cell volume and the phasic part of the chorda tympani response to acids. The Journal of General Physiology. 127: 15-34. PMID 16380442 DOI: 10.1085/Jgp.200509384  0.785
2005 Lyall V, Heck GL, Phan TH, Mummalaneni S, Malik SA, Vinnikova AK, Desimone JA. Ethanol modulates the VR-1 variant amiloride-insensitive salt taste receptor. II. Effect on chorda tympani salt responses. The Journal of General Physiology. 125: 587-600. PMID 15928404 DOI: 10.1085/Jgp.200509264  0.784
2005 Lyall V, Heck GL, Phan TH, Mummalaneni S, Malik SA, Vinnikova AK, DeSimone JA. Ethanol modulates the VR-1 variant amiloride-insensitive salt taste receptor. I. Effect on TRC volume and Na+ flux. The Journal of General Physiology. 125: 569-85. PMID 15928403 DOI: 10.1085/Jgp.200409213  0.781
2005 Lyall V, Heck GL, Vinnikova AK, Ghosh S, Phan TH, Desimone JA. A novel vanilloid receptor-1 (VR-1) variant mammalian salt taste receptor. Chemical Senses. 30: i42-3. PMID 15738186 DOI: 10.1093/Chemse/Bjh104  0.733
2004 Lyall V, Heck GL, Vinnikova AK, Ghosh S, Phan TH, Alam RI, Russell OF, Malik SA, Bigbee JW, DeSimone JA. The mammalian amiloride-insensitive non-specific salt taste receptor is a vanilloid receptor-1 variant. The Journal of Physiology. 558: 147-59. PMID 15146042 DOI: 10.1113/Jphysiol.2004.065656  0.782
2004 Lyall V, Alam RI, Malik SA, Phan TH, Vinnikova AK, Heck GL, DeSimone JA. Basolateral Na+-H+ exchanger-1 in rat taste receptor cells is involved in neural adaptation to acidic stimuli. The Journal of Physiology. 556: 159-73. PMID 14724181 DOI: 10.1113/Jphysiol.2003.057745  0.803
2004 Vinnikova AK, Alam RI, Malik SA, Ereso GL, Feldman GM, McCarty JM, Knepper MA, Heck GL, DeSimone JA, Lyall V. Na+-H+ exchange activity in taste receptor cells. Journal of Neurophysiology. 91: 1297-313. PMID 14602837 DOI: 10.1152/Jn.00809.2003  0.768
2003 Feldman GM, Mogyorosi A, Heck GL, DeSimone JA, Santos CR, Clary RA, Lyall V. Salt-evoked lingual surface potential in humans. Journal of Neurophysiology. 90: 2060-4. PMID 12736236 DOI: 10.1152/Jn.00158.2003  0.767
2002 Lyall V, Alam RI, Phan TH, Russell OF, Malik SA, Heck GL, DeSimone JA. Modulation of rat chorda tympani NaCl responses and intracellular Na+ activity in polarized taste receptor cells by pH. The Journal of General Physiology. 120: 793-815. PMID 12451050 DOI: 10.1085/Jgp.20028656  0.793
2002 Lyall V, Alam RI, Phan TH, Phan DQ, Heck GL, DeSimone JA. Excitation and adaptation in the detection of hydrogen ions by taste receptor cells: a role for cAMP and Ca(2+). Journal of Neurophysiology. 87: 399-408. PMID 11784758 DOI: 10.1152/Jn.00331.2001  0.796
2001 DeSimone JA, Lyall V, Heck GL, Feldman GM. Acid detection by taste receptor cells. Respiration Physiology. 129: 231-45. PMID 11738657 DOI: 10.1016/S0034-5687(01)00293-6  0.773
2001 DeSimone JA, Lyall V, Heck GL, Phan TH, Alam RI, Feldman GM, Buch RM. A novel pharmacological probe links the amiloride-insensitive NaCl, KCl, and NH(4)Cl chorda tympani taste responses. Journal of Neurophysiology. 86: 2638-41. PMID 11698552 DOI: 10.1152/Jn.2001.86.5.2638  0.802
2001 Lyall V, Alam RI, Phan DQ, Ereso GL, Phan TH, Malik SA, Montrose MH, Chu S, Heck GL, Feldman GM, DeSimone JA. Decrease in rat taste receptor cell intracellular pH is the proximate stimulus in sour taste transduction. American Journal of Physiology. Cell Physiology. 281: C1005-13. PMID 11502578 DOI: 10.1152/Ajpcell.2001.281.3.C1005  0.777
2000 Hendricks SJ, Stewart RE, Heck GL, DeSimone JA, Hill DL. Development of rat chorda tympani sodium responses: evidence for age-dependent changes in global amiloride-sensitive Na(+) channel kinetics. Journal of Neurophysiology. 84: 1531-44. PMID 10980025 DOI: 10.1152/Jn.2000.84.3.1531  0.815
1999 Lyall V, Heck GL, DeSimone JA, Feldman GM. Effects of osmolarity on taste receptor cell size and function. The American Journal of Physiology. 277: C800-13. PMID 10516110 DOI: 10.1152/Ajpcell.1999.277.4.C800  0.793
1999 Delwiche JF, Halpern BP, Desimone JA. Anion size of sodium salts and simple taste reaction times. Physiology & Behavior. 66: 27-32. PMID 10222469 DOI: 10.1016/S0031-9384(98)00273-X  0.398
1998 Stewart RE, Lyall V, Feldman GM, Heck GL, DeSimone JA. Acid-induced responses in hamster chorda tympani and intracellular pH tracking by taste receptor cells. American Journal of Physiology. Cell Physiology. 275: C227-C238. PMID 29591172 DOI: 10.1152/ajpcell.1998.275.1.C227  0.8
1998 Stewart RE, Lyall V, Feldman GM, Heck GL, DeSimone JA. Acid-induced responses in hamster chorda tympani and intracellular pH tracking by taste receptor cells. The American Journal of Physiology. 275: C227-38. PMID 9688854 DOI: 10.1152/Ajpcell.1998.275.1.C227  0.826
1998 Kloub MA, Heck GL, DeSimone JA. Self-inhibition in Ca2+ -evoked taste responses: a novel tool for functional dissection of salt taste transduction mechanisms. Journal of Neurophysiology. 79: 911-21. PMID 9463452 DOI: 10.1152/Jn.1998.79.2.911  0.785
1997 Lyall V, Feldman GM, Heck GL, DeSimone JA. Effects of extracellular pH, PCO2, and HCO3- on intracellular pH in isolated rat taste buds. The American Journal of Physiology. 273: C1008-19. PMID 9316422 DOI: 10.1152/Ajpcell.1997.273.3.C1008  0.737
1997 Kloub MA, Heck GL, DeSimone JA. Chorda tympani responses under lingual voltage clamp: implications for NH4 salt taste transduction. Journal of Neurophysiology. 77: 1393-406. PMID 9084605 DOI: 10.1152/Jn.1997.77.3.1393  0.808
1997 Stewart RE, DeSimone JA, Hill DL. New perspectives in a gustatory physiology: transduction, development, and plasticity. The American Journal of Physiology. 272: C1-26. PMID 9038806 DOI: 10.1152/Ajpcell.1997.272.1.C1  0.615
1996 Stewart RE, Heck GL, Desimone JA. Taste-mixture suppression: functional dissection of cellular and paracellular origins. Journal of Neurophysiology. 75: 2124-8. PMID 8734608 DOI: 10.1152/Jn.1996.75.5.2124  0.816
1995 DeSimone JA, Callaham EM, Heck GL. Chorda tympani taste response of rat to hydrochloric acid subject to voltage-clamped lingual receptive field. The American Journal of Physiology. 268: C1295-300. PMID 7762623 DOI: 10.1152/Ajpcell.1995.268.5.C1295  0.788
1994 Ye Q, Heck GL, DeSimone JA. Effects of voltage perturbation of the lingual receptive field on chorda tympani responses to Na+ and K+ salts in the rat: implications for gustatory transduction. The Journal of General Physiology. 104: 885-907. PMID 7876827 DOI: 10.1085/Jgp.104.5.885  0.792
1993 Ye Q, Heck GL, DeSimone JA. Voltage dependence of the rat chorda tympani response to Na+ salts: implications for the functional organization of taste receptor cells. Journal of Neurophysiology. 70: 167-78. PMID 8395573 DOI: 10.1152/Jn.1993.70.1.167  0.821
1993 Ye Q, Stewart RE, Heck GL, Hill DL, DeSimone JA. Dietary Na(+)-restriction prevents development of functional Na+ channels in taste cell apical membranes: proof by in vivo membrane voltage perturbation. Journal of Neurophysiology. 70: 1713-6. PMID 8283226 DOI: 10.1152/Jn.1993.70.4.1713  0.825
1993 DeSimone JA, Ye Q, Heck GL. Ion pathways in the taste bud and their significance for transduction. Ciba Foundation Symposium. 179: 218-29; discussion 2. PMID 7513272  0.8
1991 Ye Q, Heck GL, DeSimone JA. The anion paradox in sodium taste reception: resolution by voltage-clamp studies. Science (New York, N.Y.). 254: 724-6. PMID 1948054 DOI: 10.1126/Science.1948054  0.785
1990 Béhé P, DeSimone JA, Avenet P, Lindemann B. Membrane currents in taste cells of the rat fungiform papilla. Evidence for two types of Ca currents and inhibition of K currents by saccharin. The Journal of General Physiology. 96: 1061-84. PMID 2280253 DOI: 10.1085/jgp.96.5.1061  0.328
1989 Heck GL, Persaud KC, DeSimone JA. Direct measurement of translingual epithelial NaCl and KCl currents during the chorda tympani taste response. Biophysical Journal. 55: 843-57. PMID 2541822 DOI: 10.1016/S0006-3495(89)82884-X  0.78
1988 Mierson S, DeSimone SK, Heck GL, DeSimone JA. Sugar-activated ion transport in canine lingual epithelium. Implications for sugar taste transduction. The Journal of General Physiology. 92: 87-111. PMID 3171536 DOI: 10.1085/Jgp.92.1.87  0.788
1988 Persaud KC, Heck GL, DeSimone SK, Getchell TV, DeSimone JA. Ion transport across the frog olfactory mucosa: the action of cyclic nucleotides on the basal and odorant-stimulated states. Biochimica Et Biophysica Acta. 944: 49-62. PMID 2843236 DOI: 10.1016/0005-2736(88)90315-X  0.757
1987 Getchell ML, Zielinski B, DeSimone JA, Getchell TV. Odorant stimulation of secretory and neural processes in the salamander olfactory mucosa. Journal of Comparative Physiology. a, Sensory, Neural, and Behavioral Physiology. 160: 155-68. PMID 3572846 DOI: 10.1007/Bf00609723  0.397
1987 Persaud KC, DeSimone JA, Getchell ML, Heck GL, Getchell TV. Ion transport across the frog olfactory mucosa: the basal and odorant-stimulated states. Biochimica Et Biophysica Acta. 902: 65-79. PMID 2440480 DOI: 10.1016/0005-2736(87)90136-2  0.757
1986 Biber TU, DeSimone JA, Drewnowska K. Potential dependence of unidirectional chloride fluxes across isolated frog skin. Biochimica Et Biophysica Acta. 862: 27-38. PMID 3490276 DOI: 10.1016/0005-2736(86)90465-7  0.395
1985 Mierson S, Heck GL, DeSimone SK, Biber TU, DeSimone JA. The identity of the current carriers in canine lingual epithelium in vitro. Biochimica Et Biophysica Acta. 816: 283-93. PMID 4005245 DOI: 10.1016/0005-2736(85)90496-1  0.766
1985 DeSimone JA, Ferrell F. Analysis of amiloride inhibition of chorda tympani taste response of rat to NaCl. The American Journal of Physiology. 249: R52-61. PMID 2409823  0.341
1984 Heck GL, Mierson S, DeSimone JA. Salt taste transduction occurs through an amiloride-sensitive sodium transport pathway. Science (New York, N.Y.). 223: 403-5. PMID 6691151 DOI: 10.1126/Science.6691151  0.779
1984 Desimone JA, Heck GL, Mierson S, Desimone SK. The active ion transport properties of canine lingual epithelia in vitro. Implications for gustatory transduction. The Journal of General Physiology. 83: 633-56. PMID 6330275 DOI: 10.1085/Jgp.83.5.633  0.799
1984 Heck GL, DeSimone JA, Getchell TV. Evidence for electrogenic active ion transport across the frog olfactory mucosa in vitro Chemical Senses. 9: 273-283. DOI: 10.1093/Chemse/9.3.273  0.72
1981 DeSimone JA, Heck GL, DeSimone SK. Active ion transport in dog tongue: a possible role in taste. Science (New York, N.Y.). 214: 1039-41. PMID 7302576 DOI: 10.1126/Science.7302576  0.764
1980 Biber TU, Mullen TL, DeSimone JA. Effect of FeCl3 on ion transport in isolated frog skin. The Journal of Membrane Biology. 52: 133-9. PMID 6965989 DOI: 10.1007/Bf01869118  0.398
1980 Getchell TV, Heck GL, DeSimone JA, Price S. The location of olfactory receptor sites. Inferences from latency measurements. Biophysical Journal. 29: 397-411. PMID 6794658 DOI: 10.1016/S0006-3495(80)85142-3  0.736
1980 DeSimone JA, Heck GL. Surface active taste modifiers: a comparison of the physical and psychophysical properties of gymnemic acid and sodium lauryl sulfate Chemical Senses. 5: 317-330. DOI: 10.1093/Chemse/5.4.317  0.706
1980 Desimone JA, Heck GL. An analysis of the effects of stimulus transport and membrane charge on the salt, acid and water-response of mammals Chemical Senses. 5: 295-316. DOI: 10.1093/Chemse/5.4.295  0.736
1978 Desimone JA, Price S. An alternative to allosteric interactions as causes of sigmoid dose versus response curves. Application to glucose-induced secretion of insulin. Biochimica Et Biophysica Acta. 538: 120-6. PMID 339957 DOI: 10.1016/0304-4165(78)90256-8  0.312
1977 Price S, Desimone JA. Models of taste receptor cell stimulation Chemical Senses and Flavor. 2: 427-456. DOI: 10.1093/Chemse/2.4.427  0.313
Low-probability matches (unlikely to be authored by this person)
1988 Mierson S, Welter ME, Gennings C, DeSimone JA. Lingual epithelium of spontaneously hypertensive rats has decreased short-circuit current in response to NaCl. Hypertension. 11: 519-22. PMID 3384467  0.3
2000 DeSimone JA. Focus on "rapid entry of bitter and sweet tastants into liposomes and taste cells: implications for signal transduction". American Journal of Physiology. Cell Physiology. 278: C13-6. PMID 10644506 DOI: 10.1152/Ajpcell.2000.278.1.C13  0.298
1977 Pennline JA, Rosenbaum JS, Desimone JA, Mikulecky DC. A nonlinear boundary value problem arising in the structure of the double layer at an enzymatic surface Mathematical Biosciences. 37: 1-17. DOI: 10.1016/0025-5564(77)90074-8  0.28
1976 DeSimone JA, Price S. A model for the stimulation of taste receptor cells by salt. Biophysical Journal. 16: 869-81. PMID 938727 DOI: 10.1016/S0006-3495(76)85737-2  0.277
2018 Ramsey IS, DeSimone JA. Correction: Otopetrin-1: A sour-tasting proton channel. The Journal of General Physiology. PMID 29769228 DOI: 10.1085/Jgp.20181200305102018C  0.267
1977 DeSimone JA. Perturbations in the structure of the double layer at an enzymic surface. Journal of Theoretical Biology. 68: 225-40. PMID 926794 DOI: 10.1016/0022-5193(77)90161-8  0.262
2013 DeSimone JA, Beauchamp GK, Drewnowski A, Johnson GH. Sodium in the food supply: challenges and opportunities. Nutrition Reviews. 71: 52-9. PMID 23282251 DOI: 10.1111/Nure.12006  0.256
1997 Lyall V, Feldman GM, Heck GL, Desimone JA. Effec ts of extracellular pH, Pco 2, and HCO 3 - on intracellular pH in isolated rat taste buds American Journal of Physiology. 273: C953-C961.  0.244
1978 DeSimone JA. The electrostatic contribution of divalent ions to the surface pressure of charged monolayers Journal of Colloid and Interface Science. 67: 381-383. DOI: 10.1016/0021-9797(78)90023-1  0.241
1991 DeSimone JA, Heck GL, Ye Q. Electrophysiological studies of salt-sensitive taste receptors Conference Proceedings - Ieee Southeastcon. 1: 286-288.  0.238
1978 DeSimone JA, Pennline JA. A new asymptotic analysis of the nth order reaction-diffusion problem: analytical and numerical studies Mathematical Biosciences. 40: 303-318. DOI: 10.1016/0025-5564(78)90091-3  0.229
1991 DeSimone JA. Transduction in taste receptors. Nutrition (Burbank, Los Angeles County, Calif.). 7: 146-9. PMID 1802198  0.212
1980 Wyatt JL, Mikulecky DC, DeSimone JA. Network modelling of reaction-diffusion systems and their numerical solution using spice Chemical Engineering Science. 35: 2115-2127. DOI: 10.1016/0009-2509(80)85035-4  0.2
2010 DeSimone JA, Lyall V. Amiloride-Sensitive Ion Channels The Senses: a Comprehensive Reference. 4: 281-288. DOI: 10.1016/B978-012370880-9.00086-4  0.182
2010 DuBois GE, DeSimone JA, Lyall V. Chemistry of Gustatory Stimuli The Senses: a Comprehensive Reference. 4: 27-74. DOI: 10.1016/B978-012370880-9.00071-2  0.126
1992 Silver SM, DeSimone JA, Smith DA, Sterns RH. Dialysis disequilibrium syndrome (DDS) in the rat: role of the "reverse urea effect". Kidney International. 42: 161-6. PMID 1635345  0.115
2015 Murphy TP, Luu DD, DeSimone JA, O'Brien TC, Lally CJ, Lindblad JJ, Webster SM. A Behavioral Assay for Mechanosensation of MARCM-based Clones in Drosophila melanogaster. Journal of Visualized Experiments : Jove. PMID 26780205 DOI: 10.3791/53537  0.113
1973 DeSimone JA, Caplan SR. Symmetry and the stationary state behavior of enzyme membranes. Journal of Theoretical Biology. 39: 523-44. PMID 4730016 DOI: 10.1016/0022-5193(73)90066-0  0.111
2015 DeSimone JA, James LR. An Item Analysis of the Conditional Reasoning Test of Aggression. The Journal of Applied Psychology. PMID 26011720 DOI: 10.1037/Apl0000026  0.106
2014 Kakar R, Rommel J, McKinley-Grant L, Shenoy AG, DeSimone JA. Hypersensitivity to romidepsin. Journal of the American Academy of Dermatology. 70: e21-2. PMID 24355282 DOI: 10.1016/j.jaad.2013.09.040  0.104
1987 DESIMONE J. Principles and models of biological transport Bulletin of Mathematical Biology. 49: 766-767. DOI: 10.1016/S0092-8240(87)90023-1  0.095
2013 Guenova E, Watanabe R, Teague JE, Desimone JA, Jiang Y, Dowlatshahi M, Schlapbach C, Schaekel K, Rook AH, Tawa M, Fisher DC, Kupper TS, Clark RA. TH2 cytokines from malignant cells suppress TH1 responses and enforce a global TH2 bias in leukemic cutaneous T-cell lymphoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 3755-63. PMID 23785046 DOI: 10.1158/1078-0432.CCR-12-3488  0.092
1985 DeSimone JA. ELECTRICAL DOUBLE LAYERS IN MODEL MONOLAYER AND EPITHELIAL TRANSPORT SYSTEMS Electrochemical Society Extended Abstracts. 85: 647.  0.087
1978 DeSimone JA, Price S. The sigmoid dose-response relation for glucose induced insulin secretion from pancreatic islets Biophysical Journal. 21: 133a.  0.086
2003 Leslie Redpath J, Bengtsson U, DeSimone J, Lao X, Wang X, Stanbridge EJ. Sticky anaphase aberrations after G2-phase arrest of gamma-irradiated human skin fibroblasts: TP53 independence of formation and TP53 dependence of consequences. Radiation Research. 159: 57-71. PMID 12492369 DOI: 10.1667/0033-7587(2003)159[0057:Saaagp]2.0.Co;2  0.084
2011 Schoen JL, DeSimone JA, James LR. Exploring joint variance between independent variables and a criterion: Meaning, effect, and size Organizational Research Methods. 14: 674-695. DOI: 10.1177/1094428110381787  0.069
2015 Desimone JA, Harms PD, Desimone AJ. Best practice recommendations for data screening Journal of Organizational Behavior. 36: 171-181. DOI: 10.1002/Job.1962  0.069
1973 DeSimone JA, Caplan SR. The determination of local reaction and diffusion parameters of enzyme membranes from global measurements. Biochemistry. 12: 3032-9. PMID 4730497 DOI: 10.1021/Bi00740A014  0.062
1973 Desimone JA, Beil DL, Scriven LE. Ferroin-collodion membranes: dynamic concentration patterns in planar membranes. Science (New York, N.Y.). 180: 946-8. PMID 17735920 DOI: 10.1126/science.180.4089.946  0.056
2004 DeSimone JA, Ojha A, Pathak R, Cohn J. Successful desensitization to enfuvirtide after a hypersensitivity reaction in an HIV-1-infected man. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 39: e110-2. PMID 15546072 DOI: 10.1086/425502  0.045
2012 Alloo A, DeSimone JA, Kupper TS. Mycosis fungoides presenting at the site of a transdermal estradiol patch. Journal of the American Academy of Dermatology. 67: e207-8. PMID 23062916 DOI: 10.1016/j.jaad.2012.02.035  0.045
1983 DeSimone JA. Diffusion barrier in the small intestine. Science (New York, N.Y.). 220: 221-2. PMID 6828892  0.041
2000 DeSimone JA, Beavis KG, Eschelman DJ, Henning KJ. Sustained bacteremia associated with transjugular intrahepatic portosystemic shunt (TIPS). Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 30: 384-6. PMID 10671346 DOI: 10.1086/313653  0.04
2013 DeSimone JA, Guenova E, Carter JB, Chaney KS, Aldridge JR, Noell CM, Dorosario AA, Hansen JL, Kupper TS, Devlin PM. Low-dose high-dose-rate brachytherapy in the treatment of facial lesions of cutaneous T-cell lymphoma. Journal of the American Academy of Dermatology. 69: 61-5. PMID 23453243 DOI: 10.1016/j.jaad.2012.12.975  0.038
2013 James LR, LeBreton JM, Mitchell TR, Smith DR, DeSimone JA, Cookson R, Lee HJ. Use of conditional reasoning to measure the power motive Modern Research Methods For the Study of Behavior in Organizations. 233-264. DOI: 10.4324/9780203585146  0.037
2015 DeSimone JA, Sodha P, Ignatova D, Dummer R, Cozzio A, Guenova E. Recent advances in primary cutaneous T-cell lymphoma. Current Opinion in Oncology. 27: 128-33. PMID 25594623 DOI: 10.1097/CCO.0000000000000161  0.036
2014 Guenova E, Schanz S, Hoetzenecker W, DeSimone JA, Mehra T, Voykov B, Urosevic-Maiwald M, Berneburg M, Dummer R, French LE, Kerl K, Kamarashev J, Fierlbeck G, Cozzio A. Systemic corticosteroids for subcutaneous panniculitis-like T-cell lymphoma. The British Journal of Dermatology. 171: 891-4. PMID 24725144 DOI: 10.1111/bjd.13053  0.033
2014 Desimone JA. Will Exploring the Darkness Prove Enlightening? Five Questions About the "Maladaptive Big Five" Industrial and Organizational Psychology. 7: 126-130. DOI: 10.1111/iops.12120  0.033
2014 Desimone JA. When It's Incorrect to Correct: A Brief History and Cautionary Note Industrial and Organizational Psychology. 7: 527-531. DOI: 10.1111/iops.12189  0.03
2014 Shah BM, Schafer JJ, Desimone JA. Dolutegravir: a new integrase strand transfer inhibitor for the treatment of HIV. Pharmacotherapy. 34: 506-20. PMID 24347095 DOI: 10.1002/phar.1386  0.027
2000 DeSimone JA, Pomerantz RJ, Babinchak TJ. Inflammatory reactions in HIV-1-infected persons after initiation of highly active antiretroviral therapy. Annals of Internal Medicine. 133: 447-54. PMID 10975963  0.025
2006 Chulamokha L, Scholand SJ, Riggio JM, Ballas SK, Horn D, DeSimone JA. Bloodstream infections in hospitalized adults with sickle cell disease: a retrospective analysis. American Journal of Hematology. 81: 723-8. PMID 16795063 DOI: 10.1002/ajh.20692  0.02
2005 Chulamokha L, DeSimone JA, Pomerantz RJ. Antiretroviral therapy in the developing world. Journal of Neurovirology. 11: 76-80. PMID 15960241 DOI: 10.1080/13550280590900436  0.015
2003 Klibanov OM, Filicko JE, DeSimone JA, Tice DS. Sensorineural hearing loss associated with intrathecal vancomycin. The Annals of Pharmacotherapy. 37: 61-5. PMID 12503934  0.015
2005 Kannangara S, DeSimone JA, Pomerantz RJ. Attenuation of HIV-1 infection by other microbial agents. The Journal of Infectious Diseases. 192: 1003-9. PMID 16107952 DOI: 10.1086/432767  0.014
2015 DeSimone JA. New Techniques for Evaluating Temporal Consistency Organizational Research Methods. 18: 133-152. DOI: 10.1177/1094428114553061  0.013
2014 Gillette MA, Shah BM, Schafer JJ, DeSimone JA. Dolutegravir: a new integrase strand transfer inhibitor for the treatment of HIV - an alternative viewpoint. Pharmacotherapy. 34: e173-4. PMID 25182330 DOI: 10.1002/phar.1478  0.011
2015 Schafer JJ, Naples JG, Pizzi LT, Desimone JA. The effects of a pharmacist-delivered patient education programme on retention in human immunodeficiency virus care: A pilot study Journal of Pharmaceutical Health Services Research. 6: 83-89. DOI: 10.1111/jphs.12092  0.011
2002 Silverblatt A, DeSimone JA, Babinchak TJ. Acute miliary tuberculosis following laser lithotripsy Infections in Medicine. 19: 80-82.  0.01
2013 Bruminhent J, Tokarczyk MJ, Jungkind D, DeSimone JA. Rothia mucilaginosa prosthetic device infections: a case of prosthetic valve endocarditis. Journal of Clinical Microbiology. 51: 1629-32. PMID 23467598 DOI: 10.1128/JCM.03173-12  0.01
2015 Schafer JJ, Formella D, Desimone JA. Hepatitis B reverse seroconversion in a patient with well controlled HIV infection: a case report and a review of the literature. Aids (London, England). 29: 246-8. PMID 25532610 DOI: 10.1097/QAD.0000000000000532  0.01
2015 Geimer JL, Leach DJ, DeSimone JA, Rogelberg SG, Warr PB. Meetings at work: Perceived effectiveness and recommended improvements Journal of Business Research. 68: 2015-2026. DOI: 10.1016/j.jbusres.2015.02.015  0.01
2013 Fennelly AM, Slenker AK, Murphy LC, Moussouttas M, DeSimone JA. Candida cerebral abscesses: a case report and review of the literature. Medical Mycology. 51: 779-84. PMID 23651179 DOI: 10.3109/13693786.2013.789566  0.01
2012 Slenker AK, Hess BD, Jungkind DL, DeSimone JA. Fatal case of Weeksella virosa sepsis. Journal of Clinical Microbiology. 50: 4166-7. PMID 23035202 DOI: 10.1128/JCM.01761-12  0.01
2012 Chaithongwongwatthana S, Yamasmit W, Limpongsanurak S, Lumbiganon P, DeSimone JA, Baxter JK, Tolosa JE. Pneumococcal vaccination during pregnancy for preventing infant infection. The Cochrane Database of Systematic Reviews. 7: CD004903. PMID 22786493 DOI: 10.1002/14651858.CD004903.pub3  0.01
2012 Slenker AK, Desimone JA. Clostridium septicum panophthalmitis complicated by meningitis: A case report and review of the literature Infectious Diseases in Clinical Practice. 20: 305-308. DOI: 10.1097/IPC.0b013e31824f8a6d  0.01
2007 Kannangara S, Shindler D, Kunimoto DY, Sell B, DeSimone JA. Candidemia complicated by endophthalmitis: a prospective analysis. European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology. 26: 839-41. PMID 17668252 DOI: 10.1007/s10096-007-0372-7  0.01
2006 Chaithongwongwatthana S, Yamasmit W, Limpongsanurak S, Lumbiganon P, Desimone JA, Baxter J, Tolosa JE. Pneumococcal vaccination during pregnancy for preventing infant infection. The Cochrane Database of Systematic Reviews. CD004903. PMID 16437503 DOI: 10.1002/14651858.CD004903.pub2  0.01
2005 Scholand SJ, DeSimone JA, Pomerantz RJ. Anti-HIV-1 microbicides -- 'chemical condoms' designed to limit the scourge of the HIV-1 pandemic. Current Pharmaceutical Design. 11: 3747-56. PMID 16305509 DOI: 10.2174/138161205774580688  0.01
2003 Desimone JA, Babinchak TJ, Kaulback KR, Pomerantz RJ. Treatment of Mycobacterium avium complex immune reconstitution disease in HIV-1-infected individuals. Aids Patient Care and Stds. 17: 617-22. PMID 14746655 DOI: 10.1089/108729103771928672  0.01
2003 DeSimone JA. Infection of transjugular intrahepatic portosystemic shunt devices. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 37: 740-1. PMID 12942415 DOI: 10.1086/377276  0.01
2002 DeSimone JA, Pomerantz RJ. New methods for the detection of HIV. Clinics in Laboratory Medicine. 22: 573-92, v. PMID 12244587 DOI: 10.1016/S0272-2712(02)00013-6  0.01
2002 Mamidi A, DeSimone JA, Pomerantz RJ. Central nervous system infections in individuals with HIV-1 infection. Journal of Neurovirology. 8: 158-67. PMID 12053271 DOI: 10.1080/13550280290049723  0.01
2002 Steinberg MB, DeSimone JA, Abatemarco D. Tobacco use in HIV-infected women. Annals of Internal Medicine. 136: W1. PMID 12044145  0.01
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