Federick S. Southwick - Publications

Affiliations: 
University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Microbiology Biology, Cell Biology

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Bishai EA, Sidhu GS, Li W, Dhillon J, Bohil AB, Cheney RE, Hartwig JH, Southwick FS. Myosin-X facilitates Shigella-induced membrane protrusions and cell-to-cell spread. Cellular Microbiology. 15: 353-67. PMID 23083060 DOI: 10.1111/Cmi.12051  0.435
2012 Chauncey KM, Lopez MC, Sidhu G, Szarowicz SE, Baker HV, Quinn C, Southwick FS. Bacillus anthracis' lethal toxin induces broad transcriptional responses in human peripheral monocytes. Bmc Immunology. 13: 33. PMID 22747600 DOI: 10.1186/1471-2172-13-33  0.329
2009 Szarowicz SE, During RL, Li W, Quinn CP, Tang WJ, Southwick FS. Bacillus anthracis edema toxin impairs neutrophil actin-based motility. Infection and Immunity. 77: 2455-64. PMID 19349425 DOI: 10.1128/Iai.00839-08  0.403
2007 During RL, Gibson BG, Li W, Bishai EA, Sidhu GS, Landry J, Southwick FS. Anthrax lethal toxin paralyzes actin-based motility by blocking Hsp27 phosphorylation. The Embo Journal. 26: 2240-50. PMID 17446863 DOI: 10.1038/Sj.Emboj.7601687  0.436
2006 Zhang Y, Vorobiev SM, Gibson BG, Hao B, Sidhu GS, Mishra VS, Yarmola EG, Bubb MR, Almo SC, Southwick FS. A CapG gain-of-function mutant reveals critical structural and functional determinants for actin filament severing. The Embo Journal. 25: 4458-67. PMID 16977317 DOI: 10.1038/Sj.Emboj.7601323  0.324
2005 During RL, Li W, Hao B, Koenig JM, Stephens DS, Quinn CP, Southwick FS. Anthrax lethal toxin paralyzes neutrophil actin-based motility. The Journal of Infectious Diseases. 192: 837-45. PMID 16088833 DOI: 10.1086/432516  0.458
2003 Bubb MR, Yarmola EG, Gibson BG, Southwick FS. Depolymerization of actin filaments by profilin. Effects of profilin on capping protein function. The Journal of Biological Chemistry. 278: 24629-35. PMID 12730212 DOI: 10.1074/Jbc.M302796200  0.421
2003 Southwick FS, Li W, Zhang F, Zeile WL, Purich DL. Actin-based endosome and phagosome rocketing in macrophages: activation by the secretagogue antagonists lanthanum and zinc. Cell Motility and the Cytoskeleton. 54: 41-55. PMID 12451594 DOI: 10.1002/Cm.10083  0.454
2002 Falet H, Hoffmeister KM, Neujahr R, Italiano JE, Stossel TP, Southwick FS, Hartwig JH. Importance of free actin filament barbed ends for Arp2/3 complex function in platelets and fibroblasts Proceedings of the National Academy of Sciences of the United States of America. 99: 16782-16787. PMID 12464680 DOI: 10.1073/Pnas.222652499  0.351
2002 Dickinson RB, Southwick FS, Purich DL. A direct-transfer polymerization model explains how the multiple profilin-binding sites in the actoclampin motor promote rapid actin-based motility. Archives of Biochemistry and Biophysics. 406: 296-301. PMID 12361718 DOI: 10.1016/S0003-9861(02)00212-6  0.399
2002 Zhang F, Southwick FS, Purich DL. Actin-based phagosome motility. Cell Motility and the Cytoskeleton. 53: 81-8. PMID 12211106 DOI: 10.1002/Cm.10058  0.364
2000 Southwick FS. Gelsolin and ADF/cofilin enhance the actin dynamics of motile cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 6936-8. PMID 10860951 DOI: 10.1073/Pnas.97.13.6936  0.398
2000 Southwick FS, Adamson ED, Purich DL. Shigella actin-based motility in the presence of truncated vinculin. Cell Motility and the Cytoskeleton. 45: 272-8. PMID 10744860 DOI: 10.1002/(Sici)1097-0169(200004)45:4<272::Aid-Cm3>3.0.Co;2-E  0.38
1999 Kang F, Purich DL, Southwick FS. Profilin promotes barbed-end actin filament assembly without lowering the critical concentration. The Journal of Biological Chemistry. 274: 36963-72. PMID 10601251 DOI: 10.1074/Jbc.274.52.36963  0.328
1998 Zeile WL, Condit RC, Lewis JI, Purich DL, Southwick FS. Vaccinia locomotion in host cells: Evidence for the universal involvement of actin-based motility sequences ABM-1 and ABM-2 Proceedings of the National Academy of Sciences of the United States of America. 95: 13917-13922. PMID 9811901 DOI: 10.1073/Pnas.95.23.13917  0.489
1998 Laine RO, Phaneuf KL, Cunningham CC, Kwiatkowski D, Azuma T, Southwick FS. Gelsolin, a protein that caps the barbed ends and severs actin filaments, enhances the actin-based motility of Listeria monocytogenes in host cells. Infection and Immunity. 66: 3775-82. PMID 9673261 DOI: 10.1128/Iai.66.8.3775-3782.1998  0.477
1998 Southwick FS, Purich DL. Listeria and Shigella actin-based motility in host cells. Transactions of the American Clinical and Climatological Association. 109: 160-72; discussion 1. PMID 9601135  0.451
1997 Laine RO, Zeile W, Kang F, Purich DL, Southwick FS. Vinculin proteolysis unmasks an ActA homolog for actin-based Shigella motility. The Journal of Cell Biology. 138: 1255-64. PMID 9298981 DOI: 10.1083/Jcb.138.6.1255  0.402
1997 Kang F, Laine RO, Bubb MR, Southwick FS, Purich DL. Profilin interacts with the Gly-Pro-Pro-Pro-Pro-Pro sequences of vasodilator-stimulated phosphoprotein (VASP): implications for actin-based Listeria motility. Biochemistry. 36: 8384-92. PMID 9204886 DOI: 10.1021/Bi970065N  0.392
1997 Purich DL, Southwick FS. ABM-1 and ABM-2 homology sequences: consensus docking sites for actin-based motility defined by oligoproline regions in Listeria ActA surface protein and human VASP. Biochemical and Biophysical Research Communications. 231: 686-91. PMID 9070872 DOI: 10.1006/Bbrc.1997.6158  0.308
1996 Maun NA, Speicher DW, DiNubile MJ, Southwick FS. Purification and properties of a Ca(2+)-independent barbed-end actin filament capping protein, CapZ, from human polymorphonuclear leukocytes. Biochemistry. 35: 3518-24. PMID 8639502 DOI: 10.1021/Bi952470P  0.381
1996 Zeile WL, Purich DL, Southwick FS. Recognition of two classes of oligoproline sequences in profilin-mediated acceleration of actin-based Shigella motility. The Journal of Cell Biology. 133: 49-59. PMID 8601612 DOI: 10.1083/Jcb.133.1.49  0.302
1995 Southwick FS. Gain-of-function mutations conferring actin-severing activity to human macrophage cap G. The Journal of Biological Chemistry. 270: 45-8. PMID 7814409 DOI: 10.1074/Jbc.270.1.45  0.309
1995 Southwick FS, Purich DL. Inhibition of Listeria locomotion by mosquito oostatic factor, a natural oligoproline peptide uncoupler of profilin action. Infection and Immunity. 63: 182-90. PMID 7806356 DOI: 10.1128/Iai.63.1.182-190.1995  0.521
1995 Sanger JM, Mittal B, Southwick FS, Sanger JW. Listeria monocytogenes intracellular migration: inhibition by profilin, vitamin D-binding protein and DNase I. Cell Motility and the Cytoskeleton. 30: 38-49. PMID 7728867 DOI: 10.1002/Cm.970300106  0.495
1994 Southwick FS, Purich DL. Arrest of Listeria movement in host cells by a bacterial ActA analogue: implications for actin-based motility. Proceedings of the National Academy of Sciences of the United States of America. 91: 5168-72. PMID 8197202 DOI: 10.1073/Pnas.91.11.5168  0.518
1994 Southwick FS, Purich DL. Dynamic remodeling of the actin cytoskeleton: lessons learned from Listeria locomotion. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 16: 885-91. PMID 7840767 DOI: 10.1002/Bies.950161206  0.464
1992 Sanger JM, Sanger JW, Southwick FS. Host cell actin assembly is necessary and likely to provide the propulsive force for intracellular movement of Listeria monocytogenes. Infection and Immunity. 60: 3609-19. PMID 1500169 DOI: 10.1128/Iai.60.9.3609-3619.1992  0.465
1991 Brennan PJ, Zigmond SH, Schreiber AD, Smith ER, Southwick FS. Binding of IgG containing immune complexes to human neutrophil Fc gamma RII and Fc gamma RIII induces actin polymerization by a pertussis toxin-insensitive transduction pathway. Journal of Immunology (Baltimore, Md. : 1950). 146: 4282-8. PMID 1828264  0.357
1991 Pike MC, Costello K, Southwick FS. Stimulation of human polymorphonuclear leukocyte phosphatidylinositol-4-phosphate kinase by concanavalin A and formyl-methionyl-leucyl-phenylalanine is calcium-independent. Correlation with maintenance of actin assembly. Journal of Immunology (Baltimore, Md. : 1950). 147: 2270-5. PMID 1655888  0.361
1990 Southwick FS, Young CL. The actin released from profilin--actin complexes is insufficient to account for the increase in F-actin in chemoattractant-stimulated polymorphonuclear leukocytes. The Journal of Cell Biology. 110: 1965-73. PMID 2351690 DOI: 10.1083/Jcb.110.6.1965  0.406
1990 Young CL, Southwick FS, Weber A. Kinetics of the interaction of a 41-kilodalton macrophage capping protein with actin: promotion of nucleation during prolongation of the lag period. Biochemistry. 29: 2232-40. PMID 2337601 DOI: 10.1021/Bi00461A005  0.374
1990 Dabiri GA, Sanger JM, Portnoy DA, Southwick FS. Listeria monocytogenes moves rapidly through the host-cell cytoplasm by inducing directional actin assembly. Proceedings of the National Academy of Sciences of the United States of America. 87: 6068-72. PMID 2117270 DOI: 10.1073/Pnas.87.16.6068  0.502
1989 Southwick FS, Dabiri GA, Paschetto M, Zigmond SH. Polymorphonuclear leukocyte adherence induces actin polymerization by a transduction pathway which differs from that used by chemoattractants. The Journal of Cell Biology. 109: 1561-9. PMID 2507552 DOI: 10.1083/Jcb.109.4.1561  0.328
1988 DiNubile MJ, Southwick FS. Contractile proteins in leukocytes. Methods in Enzymology. 162: 246-71. PMID 3226309 DOI: 10.1016/0076-6879(88)62081-7  0.355
1988 Southwick FS, Dabiri GA, Stossel TP. Neutrophil actin dysfunction is a genetic disorder associated with partial impairment of neutrophil actin assembly in three family members. The Journal of Clinical Investigation. 82: 1525-31. PMID 3183050 DOI: 10.1172/Jci113761  0.347
1987 Shalit M, Dabiri GA, Southwick FS. Platelet-activating factor both stimulates and 'primes' human polymorphonuclear leukocyte actin filament assembly Blood. 70: 1921-1927. PMID 3118991  0.326
1985 DiNubile MJ, Southwick FS. Effects of macrophage profilin on actin in the presence and absence of acumentin and gelsolin. The Journal of Biological Chemistry. 260: 7402-9. PMID 2987255  0.31
1984 Stossel TP, Hartwig JH, Yin HL, Southwick FS, Zaner KS. The motor of leukocytes. Federation Proceedings. 43: 2760-3. PMID 6540718  0.389
1982 Southwick FS, Hartwig JH. Acumentin, a protein in macrophages which caps the "pointed" end of action filaments. Nature. 297: 303-7. PMID 6281657 DOI: 10.1038/297303A0  0.352
1981 Southwick FS, Stossel TP. Isolation of an inhibitor of actin polymerization from human polymorphonuclear leukocytes. The Journal of Biological Chemistry. 256: 3030-6. PMID 6894143  0.314
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