Lucio G. Costa - Publications

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
Toxicology, Neuroscience Biology

152 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Costa LG. Overview of Neurotoxicology. Current Protocols in Toxicology. 74: 11.1.1-11.1.11. PMID 29117435 DOI: 10.1002/Cptx.36  0.324
2017 Roqué PJ, Costa LG. Co-Culture of Neurons and Microglia. Current Protocols in Toxicology. 74: 11.24.1-11.24.17. PMID 29117434 DOI: 10.1002/Cptx.32  0.376
2017 Shiotani M, Cole TB, Hong S, Park JJY, Griffith WC, Burbacher TM, Workman T, Costa LG, Faustman EM. Neurobehavioral assessment of mice following repeated oral exposures to domoic acid during prenatal development. Neurotoxicology and Teratology. PMID 28916171 DOI: 10.1016/J.Ntt.2017.09.002  0.319
2016 Marsillach J, Costa LG, Furlong CE. Paraoxonase-1 and Early-Life Environmental Exposures. Annals of Global Health. 82: 100-10. PMID 27325068 DOI: 10.1016/J.Aogh.2016.01.009  0.301
2016 Costa LG, Garrick JM, Roquè PJ, Pellacani C. Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More. Oxidative Medicine and Cellular Longevity. 2016: 2986796. PMID 26904161 DOI: 10.1155/2016/2986796  0.372
2015 Costa LG, Tagliaferri S, Roqué PJ, Pellacani C. Role of glutamate receptors in tetrabrominated diphenyl ether (BDE-47) neurotoxicity in mouse cerebellar granule neurons. Toxicology Letters. PMID 26640238 DOI: 10.1016/J.Toxlet.2015.11.026  0.369
2015 Costa LG, Pellacani C, Dao K, Kavanagh TJ, Roque PJ. The brominated flame retardant BDE-47 causes oxidative stress and apoptotic cell death in vitro and in vivo in mice. Neurotoxicology. 48: 68-76. PMID 25797475 DOI: 10.1016/J.Neuro.2015.03.008  0.392
2014 Zhou C, Chen J, Zhang X, Costa LG, Guizzetti M. Prenatal Ethanol Exposure Up-Regulates the Cholesterol Transporters ATP-Binding Cassette A1 and G1 and Reduces Cholesterol Levels in the Developing Rat Brain. Alcohol and Alcoholism (Oxford, Oxfordshire). PMID 25081040 DOI: 10.1093/Alcalc/Agu049  0.31
2014 Cole TB, Li WF, Co AL, Hay AM, MacDonald JW, Bammler TK, Farin FM, Costa LG, Furlong CE. Repeated gestational exposure of mice to chlorpyrifos oxon is associated with paraoxonase 1 (PON1) modulated effects in maternal and fetal tissues. Toxicological Sciences : An Official Journal of the Society of Toxicology. 141: 409-22. PMID 25070982 DOI: 10.1093/Toxsci/Kfu144  0.308
2014 Roqué PJ, Guizzetti M, Costa LG. Synaptic structure quantification in cultured neurons. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. 60: 12.22.1-12.22.32. PMID 24865645 DOI: 10.1002/0471140856.Tx1222S60  0.359
2014 Pizzurro DM, Dao K, Costa LG. Astrocytes protect against diazinon- and diazoxon-induced inhibition of neurite outgrowth by regulating neuronal glutathione. Toxicology. 318: 59-68. PMID 24561003 DOI: 10.1016/J.Tox.2014.01.010  0.804
2014 Pizzurro DM, Dao K, Costa LG. Diazinon and diazoxon impair the ability of astrocytes to foster neurite outgrowth in primary hippocampal neurons. Toxicology and Applied Pharmacology. 274: 372-82. PMID 24342266 DOI: 10.1016/J.Taap.2013.11.023  0.798
2014 Costa LG, de Laat R, Tagliaferri S, Pellacani C. A mechanistic view of polybrominated diphenyl ether (PBDE) developmental neurotoxicity. Toxicology Letters. 230: 282-94. PMID 24270005 DOI: 10.1016/J.Toxlet.2013.11.011  0.363
2014 Pellacani C, Tagliaferri S, Caglieri A, Goldoni M, Giordano G, Mutti A, Costa LG. Synergistic interactions between PBDEs and PCBs in human neuroblastoma cells Environmental Toxicology. 29: 418-427. PMID 22434561 DOI: 10.1002/Tox.21768  0.339
2013 Costa LG, Tait L, de Laat R, Dao K, Giordano G, Pellacani C, Cole TB, Furlong CE. Modulation of paraoxonase 2 (PON2) in mouse brain by the polyphenol quercetin: a mechanism of neuroprotection? Neurochemical Research. 38: 1809-18. PMID 23743621 DOI: 10.1007/S11064-013-1085-1  0.383
2013 Giordano G, Tait L, Furlong CE, Cole TB, Kavanagh TJ, Costa LG. Gender differences in brain susceptibility to oxidative stress are mediated by levels of paraoxonase-2 expression. Free Radical Biology & Medicine. 58: 98-108. PMID 23376469 DOI: 10.1016/J.Freeradbiomed.2013.01.019  0.335
2013 Giordano G, Kavanagh TJ, Faustman EM, White CC, Costa LG. Low-level domoic acid protects mouse cerebellar granule neurons from acute neurotoxicity: role of glutathione. Toxicological Sciences : An Official Journal of the Society of Toxicology. 132: 399-408. PMID 23315585 DOI: 10.1093/Toxsci/Kft002  0.361
2013 Marsillach J, Costa LG, Furlong CE. Protein adducts as biomarkers of exposure to organophosphorus compounds. Toxicology. 307: 46-54. PMID 23261756 DOI: 10.1016/J.Tox.2012.12.007  0.318
2013 Chen J, Zhang X, Kusumo H, Costa LG, Guizzetti M. Cholesterol efflux is differentially regulated in neurons and astrocytes: implications for brain cholesterol homeostasis. Biochimica Et Biophysica Acta. 1831: 263-75. PMID 23010475 DOI: 10.1016/J.Bbalip.2012.09.007  0.342
2013 Costa LG, Giordano G, Cole TB, Marsillach J, Furlong CE. Paraoxonase 1 (PON1) as a genetic determinant of susceptibility to organophosphate toxicity. Toxicology. 307: 115-22. PMID 22884923 DOI: 10.1016/J.Tox.2012.07.011  0.323
2013 Costa LG, Giordano G, Guizzetti M. Inhibition of cholinergic muscarinic signaling by ethanol: Potential mechanism of developmental neurotoxicity and biological plausibility for the beneficial effects of choline supplementation The International Journal of Alcohol and Drug Research. 2: 17. DOI: 10.7895/Ijadr.V2I3.72  0.459
2012 Pellacani C, Buschini A, Galati S, Mussi F, Franzoni S, Costa LG. Evaluation of DNA damage induced by 2 polybrominated diphenyl ether flame retardants (BDE-47 and BDE-209) in SK-N-MC cells. International Journal of Toxicology. 31: 372-9. PMID 22710639 DOI: 10.1177/1091581812449663  0.31
2012 Giordano G, Costa LG. Morphological assessment of neurite outgrowth in hippocampal neuron-astrocyte co-cultures. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit 11.16.. PMID 22549268 DOI: 10.1002/0471140856.Tx1116S52  0.401
2012 Cole TB, Fisher JC, Burbacher TM, Costa LG, Furlong CE. Neurobehavioral assessment of mice following repeated postnatal exposure to chlorpyrifos-oxon. Neurotoxicology and Teratology. 34: 311-22. PMID 22425525 DOI: 10.1016/J.Ntt.2012.02.003  0.354
2011 Giordano G, Guizzetti M, Dao K, Mattison HA, Costa LG. Ethanol impairs muscarinic receptor-induced neuritogenesis in rat hippocampal slices: Role of astrocytes and extracellular matrix proteins. Biochemical Pharmacology. 82: 1792-9. PMID 21884684 DOI: 10.1016/J.Bcp.2011.08.014  0.472
2011 Roqué PJ, Guizzetti M, Giordano G, Costa LG. Quantification of synaptic structure formation in cocultures of astrocytes and hippocampal neurons. Methods in Molecular Biology (Clifton, N.J.). 758: 361-90. PMID 21815079 DOI: 10.1007/978-1-61779-170-3_25  0.306
2011 Guizzetti M, Kavanagh TJ, Costa LG. Measurements of astrocyte proliferation. Methods in Molecular Biology (Clifton, N.J.). 758: 349-59. PMID 21815078 DOI: 10.1007/978-1-61779-170-3_24  0.301
2011 Giordano G, White CC, Costa LG. Assessment of glutathione homeostasis. Methods in Molecular Biology (Clifton, N.J.). 758: 205-14. PMID 21815068 DOI: 10.1007/978-1-61779-170-3_14  0.302
2011 Giordano G, Costa LG. Measurements of neuronal apoptosis. Methods in Molecular Biology (Clifton, N.J.). 758: 179-93. PMID 21815066 DOI: 10.1007/978-1-61779-170-3_12  0.352
2011 Giordano G, Hong S, Faustman EM, Costa LG. Measurements of cell death in neuronal and glial cells. Methods in Molecular Biology (Clifton, N.J.). 758: 171-8. PMID 21815065 DOI: 10.1007/978-1-61779-170-3_11  0.335
2011 Giordano G, Costa LG. Primary neurons in culture and neuronal cell lines for in vitro neurotoxicological studies. Methods in Molecular Biology (Clifton, N.J.). 758: 13-27. PMID 21815056 DOI: 10.1007/978-1-61779-170-3_2  0.364
2011 Cole TB, Beyer RP, Bammler TK, Park SS, Farin FM, Costa LG, Furlong CE. Repeated developmental exposure of mice to chlorpyrifos oxon is associated with paraoxonase 1 (PON1)-modulated effects on cerebellar gene expression. Toxicological Sciences : An Official Journal of the Society of Toxicology. 123: 155-69. PMID 21673326 DOI: 10.1093/Toxsci/Kfr157  0.307
2011 Guizzetti M, Moore NH, VanDeMark KL, Giordano G, Costa LG. Muscarinic receptor-activated signal transduction pathways involved in the neuritogenic effect of astrocytes in hippocampal neurons. European Journal of Pharmacology. 659: 102-7. PMID 21453700 DOI: 10.1016/J.Ejphar.2011.03.019  0.791
2011 Giordano G, Cole TB, Furlong CE, Costa LG. Paraoxonase 2 (PON2) in the mouse central nervous system: a neuroprotective role? Toxicology and Applied Pharmacology. 256: 369-78. PMID 21354197 DOI: 10.1016/J.Taap.2011.02.014  0.328
2011 Verzelloni E, Pellacani C, Tagliazucchi D, Tagliaferri S, Calani L, Costa LG, Brighenti F, Borges G, Crozier A, Conte A, Del Rio D. Antiglycative and neuroprotective activity of colon-derived polyphenol catabolites. Molecular Nutrition & Food Research. 55: S35-43. PMID 21240902 DOI: 10.1002/Mnfr.201000525  0.333
2011 Costa LG, Giordano G. Is decabromodiphenyl ether (BDE-209) a developmental neurotoxicant? Neurotoxicology. 32: 9-24. PMID 21182867 DOI: 10.1016/J.Neuro.2010.12.010  0.333
2011 Costa LG, Giordano G, Furlong CE. Pharmacological and dietary modulators of paraoxonase 1 (PON1) activity and expression: the hunt goes on. Biochemical Pharmacology. 81: 337-44. PMID 21093416 DOI: 10.1016/J.Bcp.2010.11.008  0.306
2010 Guizzetti M, Moore NH, Giordano G, VanDeMark KL, Costa LG. Ethanol inhibits neuritogenesis induced by astrocyte muscarinic receptors. Glia. 58: 1395-406. PMID 20648635 DOI: 10.1002/Glia.21015  0.796
2010 Costa LG, Giordano G, Faustman EM. Domoic acid as a developmental neurotoxin. Neurotoxicology. 31: 409-23. PMID 20471419 DOI: 10.1016/J.Neuro.2010.05.003  0.34
2010 Vitalone A, Catalani A, Cinque C, Fattori V, Matteucci P, Zuena AR, Costa LG. Long-term effects of developmental exposure to low doses of PCB 126 and methylmercury. Toxicology Letters. 197: 38-45. PMID 20450966 DOI: 10.1016/J.Toxlet.2010.04.024  0.318
2010 Furlong CE, Suzuki SM, Stevens RC, Marsillach J, Richter RJ, Jarvik GP, Checkoway H, Samii A, Costa LG, Griffith A, Roberts JW, Yearout D, Zabetian CP. Human PON1, a biomarker of risk of disease and exposure. Chemico-Biological Interactions. 187: 355-61. PMID 20338154 DOI: 10.1016/J.Cbi.2010.03.033  0.323
2010 Cole TB, Jansen K, Park S, Li WF, Furlong CE, Costa LG. The toxicity of mixtures of specific organophosphate compounds is modulated by paraoxonase 1 status. Advances in Experimental Medicine and Biology. 660: 47-60. PMID 20221870 DOI: 10.1007/978-1-60761-350-3_6  0.307
2010 Huang SC, Giordano G, Costa LG. Comparative cytotoxicity and intracellular accumulation of five polybrominated diphenyl ether congeners in mouse cerebellar granule neurons. Toxicological Sciences : An Official Journal of the Society of Toxicology. 114: 124-32. PMID 19969594 DOI: 10.1093/Toxsci/Kfp296  0.407
2010 Tagliaferri S, Caglieri A, Goldoni M, Pinelli S, Alinovi R, Poli D, Pellacani C, Giordano G, Mutti A, Costa LG. Low concentrations of the brominated flame retardants BDE-47 and BDE-99 induce synergistic oxidative stress-mediated neurotoxicity in human neuroblastoma cells. Toxicology in Vitro : An International Journal Published in Association With Bibra. 24: 116-22. PMID 19720130 DOI: 10.1016/J.Tiv.2009.08.020  0.374
2010 Rio DD, Costa LG, Lean MEJ, Crozier A. Polyphenols and health: what compounds are involved? Nutrition Metabolism and Cardiovascular Diseases. 20: 1-6. PMID 19713090 DOI: 10.1016/J.Numecd.2009.05.015  0.309
2009 VanDemark KL, Guizzetti M, Giordano G, Costa LG. Ethanol inhibits muscarinic receptor-induced axonal growth in rat hippocampal neurons. Alcoholism, Clinical and Experimental Research. 33: 1945-55. PMID 19673741 DOI: 10.1111/J.1530-0277.2009.01032.X  0.791
2009 Giordano G, Pizzurro D, VanDeMark K, Guizzetti M, Costa LG. Manganese inhibits the ability of astrocytes to promote neuronal differentiation. Toxicology and Applied Pharmacology. 240: 226-35. PMID 19524604 DOI: 10.1016/J.Taap.2009.06.004  0.756
2009 Giordano G, Li L, White CC, Farin FM, Wilkerson HW, Kavanagh TJ, Costa LG. Muscarinic receptors prevent oxidative stress-mediated apoptosis induced by domoic acid in mouse cerebellar granule cells. Journal of Neurochemistry. 109: 525-38. PMID 19200344 DOI: 10.1111/J.1471-4159.2009.05969.X  0.387
2009 VanDeMark KL, Guizzetti M, Giordano G, Costa LG. The activation of M1 muscarinic receptor signaling induces neuronal differentiation in pyramidal hippocampal neurons. The Journal of Pharmacology and Experimental Therapeutics. 329: 532-42. PMID 19190235 DOI: 10.1124/Jpet.108.150128  0.785
2009 Giordano G, Kavanagh TJ, Costa LG. Mouse cerebellar astrocytes protect cerebellar granule neurons against toxicity of the polybrominated diphenyl ether (PBDE) mixture DE-71. Neurotoxicology. 30: 326-9. PMID 19150461 DOI: 10.1016/J.Neuro.2008.12.009  0.431
2009 Moore NH, Costa LG, Shaffer SA, Goodlett DR, Guizzetti M. Shotgun proteomics implicates extracellular matrix proteins and protease systems in neuronal development induced by astrocyte cholinergic stimulation. Journal of Neurochemistry. 108: 891-908. PMID 19077055 DOI: 10.1111/j.1471-4159.2008.05836.x  0.389
2008 Vitalone A, Catalani A, Chiodi V, Cinque C, Fattori V, Goldoni M, Matteucci P, Poli D, Zuena AR, Costa LG. Neurobehavioral assessment of rats exposed to low doses of PCB126 and methyl mercury during development. Environmental Toxicology and Pharmacology. 25: 103-13. PMID 21783843 DOI: 10.1016/J.Etap.2007.09.006  0.308
2008 Guizzetti M, Moore NH, Giordano G, Costa LG. Modulation of neuritogenesis by astrocyte muscarinic receptors. The Journal of Biological Chemistry. 283: 31884-97. PMID 18755690 DOI: 10.1074/Jbc.M801316200  0.463
2008 Eaton DL, Daroff RB, Autrup H, Bridges J, Buffler P, Costa LG, Coyle J, McKhann G, Mobley WC, Nadel L, Neubert D, Schulte-Hermann R, Spencer PS. Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment. Critical Reviews in Toxicology. 38: 1-125. PMID 18726789 DOI: 10.1080/10408440802272158  0.336
2008 Giordano G, Kavanagh TJ, Costa LG. Neurotoxicity of a polybrominated diphenyl ether mixture (DE-71) in mouse neurons and astrocytes is modulated by intracellular glutathione levels. Toxicology and Applied Pharmacology. 232: 161-8. PMID 18656495 DOI: 10.1016/J.Taap.2008.06.018  0.422
2008 Bal-Price AK, Suñol C, Weiss DG, van Vliet E, Westerink RH, Costa LG. Application of in vitro neurotoxicity testing for regulatory purposes: Symposium III summary and research needs. Neurotoxicology. 29: 520-31. PMID 18417220 DOI: 10.1016/J.Neuro.2008.02.008  0.302
2008 Tsuji R, Fattori V, Abe S, Costa LG, Kobayashi K. Effects of postnatal ethanol exposure at different developmental phases on neurotrophic factors and phosphorylated proteins on signal transductions in rat brain. Neurotoxicology and Teratology. 30: 228-36. PMID 18358698 DOI: 10.1016/J.Ntt.2008.01.004  0.379
2008 Giordano G, Klintworth HM, Kavanagh TJ, Costa LG. Apoptosis induced by domoic acid in mouse cerebellar granule neurons involves activation of p38 and JNK MAP kinases. Neurochemistry International. 52: 1100-5. PMID 18164102 DOI: 10.1016/J.Neuint.2007.11.004  0.356
2008 Costa LG, Giordano G, Guizzetti M, Vitalone A. Neurotoxicity of pesticides: a brief review. Frontiers in Bioscience : a Journal and Virtual Library. 13: 1240-9. PMID 17981626 DOI: 10.2741/2758  0.313
2008 Fattori V, Abe S, Kobayashi K, Costa LG, Tsuji R. Effects of postnatal ethanol exposure on neurotrophic factors and signal transduction pathways in rat brain. Journal of Applied Toxicology : Jat. 28: 370-6. PMID 17685400 DOI: 10.1002/Jat.1288  0.367
2007 Costa LG, Giordano G. Developmental neurotoxicity of polybrominated diphenyl ether (PBDE) flame retardants. Neurotoxicology. 28: 1047-67. PMID 17904639 DOI: 10.1016/J.Neuro.2007.08.007  0.327
2007 Giordano G, White CC, Mohar I, Kavanagh TJ, Costa LG. Glutathione levels modulate domoic acid induced apoptosis in mouse cerebellar granule cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 100: 433-44. PMID 17804861 DOI: 10.1093/Toxsci/Kfm236  0.34
2007 Guizzetti M, Costa LG. Cholesterol homeostasis in the developing brain: a possible new target for ethanol. Human & Experimental Toxicology. 26: 355-60. PMID 17615117 DOI: 10.1177/0960327107078412  0.362
2007 Costa LG, Fattori V, Giordano G, Vitalone A. An in vitro approach to assess the toxicity of certain food contaminants: methylmercury and polychlorinated biphenyls. Toxicology. 237: 65-76. PMID 17553607 DOI: 10.1016/J.Tox.2007.05.003  0.38
2007 Guizzetti M, Chen J, Oram JF, Tsuji R, Dao K, Möller T, Costa LG. Ethanol induces cholesterol efflux and up-regulates ATP-binding cassette cholesterol transporters in fetal astrocytes. The Journal of Biological Chemistry. 282: 18740-9. PMID 17478430 DOI: 10.1074/Jbc.M702398200  0.359
2007 Giordano G, Afsharinejad Z, Guizzetti M, Vitalone A, Kavanagh TJ, Costa LG. Organophosphorus insecticides chlorpyrifos and diazinon and oxidative stress in neuronal cells in a genetic model of glutathione deficiency. Toxicology and Applied Pharmacology. 219: 181-9. PMID 17084875 DOI: 10.1016/J.Taap.2006.09.016  0.398
2006 Giordano G, White CC, McConnachie LA, Fernandez C, Kavanagh TJ, Costa LG. Neurotoxicity of domoic Acid in cerebellar granule neurons in a genetic model of glutathione deficiency. Molecular Pharmacology. 70: 2116-26. PMID 17000861 DOI: 10.1124/Mol.106.027748  0.371
2005 Furlong CE, Cole TB, Jarvik GP, Pettan-Brewer C, Geiss GK, Richter RJ, Shih DM, Tward AD, Lusis AJ, Costa LG. Role of paraoxonase (PON1) status in pesticide sensitivity: genetic and temporal determinants. Neurotoxicology. 26: 651-9. PMID 16112327 DOI: 10.1016/J.Neuro.2004.08.002  0.318
2005 Guizzetti M, Pathak S, Giordano G, Costa LG. Effect of organophosphorus insecticides and their metabolites on astroglial cell proliferation. Toxicology. 215: 182-90. PMID 16102884 DOI: 10.1016/J.Tox.2005.07.004  0.344
2005 Giordano G, Sánchez-Pérez AM, Montoliu C, Berezney R, Malyavantham K, Costa LG, Calvete JJ, Felipo V. Activation of NMDA receptors induces protein kinase A-mediated phosphorylation and degradation of matrin 3. Blocking these effects prevents NMDA-induced neuronal death. Journal of Neurochemistry. 94: 808-18. PMID 16000164 DOI: 10.1111/J.1471-4159.2005.03235.X  0.367
2005 Furlong CE, Cole TB, Walter BJ, Shih DM, Tward A, Lusis AJ, Timchalk C, Richter RJ, Costa LG. Paraoxonase 1 (PON1) status and risk of insecticide exposure. Journal of Biochemical and Molecular Toxicology. 19: 182-3. PMID 15977192 DOI: 10.1002/Jbt.20079  0.322
2005 Guizzetti M, Costa LG. Disruption of cholesterol homeostasis in the developing brain as a potential mechanism contributing to the developmental neurotoxicity of ethanol: an hypothesis. Medical Hypotheses. 64: 563-7. PMID 15617867 DOI: 10.1016/J.Mehy.2004.05.019  0.344
2005 Giordano G, Sanchez-Perez AM, Burgal M, Montoliu C, Costa LG, Felipo V. Chronic exposure to ammonia induces isoform-selective alterations in the intracellular distribution and NMDA receptor-mediated translocation of protein kinase C in cerebellar neurons in culture. Journal of Neurochemistry. 92: 143-57. PMID 15606904 DOI: 10.1111/J.1471-4159.2004.02852.X  0.373
2005 Zurich MG, Honegger P, Schilter B, Costa LG, Monnet-Tschudi F. Involvement of glial cells in the neurotoxicity of parathion and chlorpyrifos. Toxicology and Applied Pharmacology. 201: 97-104. PMID 15541749 DOI: 10.1016/J.Taap.2004.05.003  0.412
2004 Madia F, Giordano G, Fattori V, Vitalone A, Branchi I, Capone F, Costa LG. Differential in vitro neurotoxicity of the flame retardant PBDE-99 and of the PCB Aroclor 1254 in human astrocytoma cells. Toxicology Letters. 154: 11-21. PMID 15475174 DOI: 10.1016/J.Toxlet.2004.06.013  0.357
2004 Guizzetti M, Thompson BD, Kim Y, VanDeMark K, Costa LG. Role of phospholipase D signaling in ethanol-induced inhibition of carbachol-stimulated DNA synthesis of 1321N1 astrocytoma cells. Journal of Neurochemistry. 90: 646-53. PMID 15255942 DOI: 10.1111/J.1471-4159.2004.02541.X  0.781
2004 Costa LG, Vitalone A, Guizzetti M. Signal transduction mechanisms involved in the antiproliferative effects of ethanol in glial cells. Toxicology Letters. 149: 67-73. PMID 15093250 DOI: 10.1016/J.Toxlet.2003.12.020  0.315
2003 Tsuji R, Guizzetti M, Costa LG. In vivo ethanol decreases phosphorylated MAPK and p70S6 kinase in the developing rat brain. Neuroreport. 14: 1395-9. PMID 12876481 DOI: 10.1097/01.wnr.0000071763.92388.41  0.382
2003 Burry M, Guizzetti M, Oberdoerster J, Costa LG. Developmental neurotoxicity of toluene: in vivo and in vitro effects on astroglial cells. Developmental Neuroscience. 25: 14-9. PMID 12876426 DOI: 10.1159/000071463  0.391
2003 Branchi I, Capone F, Alleva E, Costa LG. Polybrominated diphenyl ethers: neurobehavioral effects following developmental exposure. Neurotoxicology. 24: 449-62. PMID 12782110 DOI: 10.1016/S0161-813X(03)00020-2  0.342
2003 Guizzetti M, Möller T, Costa LG. Ethanol inhibits muscarinic receptor-mediated DNA synthesis and signal transduction in human fetal astrocytes. Neuroscience Letters. 344: 68-70. PMID 12781924 DOI: 10.1016/S0304-3940(03)00431-2  0.424
2003 Costa LG, Richter RJ, Li WF, Cole T, Guizzetti M, Furlong CE. Paraoxonase (PON 1) as a biomarker of susceptibility for organophosphate toxicity. Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 8: 1-12. PMID 12519632 DOI: 10.1080/13547500210148315  0.317
2002 Costa LG, Guizzetti M. Inhibition of muscarinic receptor-induced proliferation of astroglial cells by ethanol: mechanisms and implications for the fetal alcohol syndrome. Neurotoxicology. 23: 685-91. PMID 12520758 DOI: 10.1016/S0161-813X(02)00009-8  0.407
2002 Branchi I, Alleva E, Costa LG. Effects of perinatal exposure to a polybrominated diphenyl ether (PBDE 99) on mouse neurobehavioural development. Neurotoxicology. 23: 375-84. PMID 12387364 DOI: 10.1016/S0161-813X(02)00078-5  0.308
2002 Guizzetti M, Costa LG. Effect of ethanol on protein kinase Czeta and p70S6 kinase activation by carbachol: a possible mechanism for ethanol-induced inhibition of glial cell proliferation. Journal of Neurochemistry. 82: 38-46. PMID 12091463 DOI: 10.1046/J.1471-4159.2002.00942.X  0.409
2002 Costa LG, Guizzetti M, Burry M, Oberdoerster J. Developmental neurotoxicity: do similar phenotypes indicate a common mode of action? A comparison of fetal alcohol syndrome, toluene embryopathy and maternal phenylketonuria. Toxicology Letters. 127: 197-205. PMID 12052659 DOI: 10.1016/S0378-4274(01)00501-X  0.358
2002 Lu H, Guizzetti M, Costa LG. Inorganic lead activates the mitogen-activated protein kinase kinase-mitogen-activated protein kinase-p90(RSK) signaling pathway in human astrocytoma cells via a protein kinase C-dependent mechanism. The Journal of Pharmacology and Experimental Therapeutics. 300: 818-23. PMID 11861786 DOI: 10.1124/Jpet.300.3.818  0.63
2001 Costa LG, Guizzetti M, Oberdoerster J, Yagle K, Costa-Mallen P, Tita B, Bordi F, Vitalone A, Palmery M, Valeri P. Modulation of DNA synthesis by muscarinic cholinergic receptors. Growth Factors (Chur, Switzerland). 18: 227-36. PMID 11519822 DOI: 10.3109/08977190109029112  0.328
2001 Lu H, Guizzetti M, Costa LG. Inorganic lead stimulates DNA synthesis in human astrocytoma cells: role of protein kinase Calpha. Journal of Neurochemistry. 78: 590-9. PMID 11483662 DOI: 10.1046/J.1471-4159.2001.00434.X  0.63
2001 Yagle K, Lu H, Guizzetti M, Möller T, Costa LG. Activation of mitogen-activated protein kinase by muscarinic receptors in astroglial cells: role in DNA synthesis and effect of ethanol. Glia. 35: 111-20. PMID 11460267 DOI: 10.1002/Glia.1076  0.661
2001 Guizzetti M, Costa LG. Activation of phosphatidylinositol 3 kinase by muscarinic receptors in astrocytoma cells. Neuroreport. 12: 1639-42. PMID 11409731 DOI: 10.1097/00001756-200106130-00025  0.334
2001 Costa LG, Guizzetti M, Lu H, Bordi F, Vitalone A, Tita B, Palmery M, Valeri P, Silvestrini B. Intracellular signal transduction pathways as targets for neurotoxicants. Toxicology. 160: 19-26. PMID 11246120 DOI: 10.1016/S0300-483X(00)00435-2  0.583
2000 Guizzetti M, Costa LG. Possible role of protein kinase C zeta in muscarinic receptor-induced proliferation of astrocytoma cells. Biochemical Pharmacology. 60: 1457-66. PMID 11020447 DOI: 10.1016/S0006-2952(00)00468-8  0.379
2000 Monnet-Tschudi F, Zurich MG, Schilter B, Costa LG, Honegger P. Maturation-dependent effects of chlorpyrifos and parathion and their oxygen analogs on acetylcholinesterase and neuronal and glial markers in aggregating brain cell cultures. Toxicology and Applied Pharmacology. 165: 175-83. PMID 10873710 DOI: 10.1006/Taap.2000.8934  0.424
2000 Catlin MC, Guizzetti M, Costa LG. Effect of ethanol on muscarinic receptor-induced calcium responses in astroglia. Journal of Neuroscience Research. 60: 345-55. PMID 10797537 DOI: 10.1002/(Sici)1097-4547(20000501)60:3<345::Aid-Jnr9>3.0.Co;2-6  0.363
2000 Wei M, Guizzetti M, Yost M, Costa LG. Exposure to 60-Hz magnetic fields and proliferation of human astrocytoma cells in vitro. Toxicology and Applied Pharmacology. 162: 166-76. PMID 10652245 DOI: 10.1006/Taap.1999.8825  0.364
1999 Costa LG, Li WF, Richter RJ, Shih DM, Lusis A, Furlong CE. The role of paraoxonase (PON1) in the detoxication of organophosphates and its human polymorphism. Chemico-Biological Interactions. 429-38. PMID 10421480 DOI: 10.1016/S0009-2797(99)00055-1  0.315
1999 Catlin MC, Guizzetti M, Costa LG. Effects of ethanol on calcium homeostasis in the nervous system: implications for astrocytes. Molecular Neurobiology. 19: 1-24. PMID 10321969 DOI: 10.1007/Bf02741375  0.339
1999 Costa LG, Guizzetti M. Muscarinic cholinergic receptor signal transduction as a potential target for the developmental neurotoxicity of ethanol. Biochemical Pharmacology. 57: 721-6. PMID 10075078 DOI: 10.1016/S0006-2952(98)00278-0  0.433
1999 Coccini T, Randine G, Li B, Manzo L, Costa LG. Effect of styrene on monoamine oxidase B activity in rat brain Journal of Toxicology and Environmental Health. 56: 59-68. PMID 9923754 DOI: 10.1080/009841099158231  0.338
1999 Castoldi AF, Barni S, Randine G, Costa LG, Manzo L. Ethanol selectively interferes with the trophic action of NMDA and carbachol on cultured cerebellar granule neurons undergoing apoptosis. Brain Research. Developmental Brain Research. 111: 279-89. PMID 9838163 DOI: 10.1016/S0165-3806(98)00135-7  0.391
1999 Yagle K, Costa LG. Effects of Alcohol on Immediate-Early Gene Expression in Primary Cultures of Rat Cortical Astrocytes Alcoholism: Clinical and Experimental Research. 23: 446-455. DOI: 10.1111/J.1530-0277.1999.Tb04136.X  0.381
1998 Guizzetti M, Wei M, Costa LG. The role of protein kinase C alpha and epsilon isozymes in DNA synthesis induced by muscarinic receptors in a glial cell line. European Journal of Pharmacology. 359: 223-33. PMID 9832394 DOI: 10.1016/S0014-2999(98)00620-7  0.325
1998 Guizzetti M, Catlin M, Costa LG. Effects of Ethanol on Glial Cell Proliferation: Relevance to the Fetal Alcohol Syndrome Pediatric Pathology & Molecular Medicine. 18: 433-443. DOI: 10.1080/15513819809168799  0.387
1998 Castoldi A, Barni S, Costa L, Manzo L. Ethanol interferes with the trophic action of NMDA and carbachol, but not with that of forskolin and gaba, on cultured cerebellar granule neurons undergoing apoptosis Toxicology Letters. 95: 109-110. DOI: 10.1016/S0378-4274(98)80433-5  0.364
1997 Guizzetti M, Catlin M, Costa LG. The effects of ethanol on glial cell proliferation: relevance to the fetal alcohol syndrome. Frontiers in Bioscience : a Journal and Virtual Library. 2: e93-8. PMID 9323212 DOI: 10.2741/A230  0.392
1996 Guizzetti M, Costa LG. Inhibition of muscarinic receptor-stimulated glial cell proliferation by ethanol. Journal of Neurochemistry. 67: 2236-45. PMID 8931454 DOI: 10.1046/J.1471-4159.1996.67062236.X  0.384
1996 Coccini T, Maestri L, Robustelli della Cuna FS, Bin L, Costa LG, Manzo L. Urinary mercapturic acid diastereoisomers in rats subchronically exposed to styrene and ethanol. Archives of Toxicology. 70: 736-41. PMID 8896719 DOI: 10.1007/S002040050334  0.338
1996 Costa LG. Biomarker research in neurotoxicology: the role of mechanistic studies to bridge the gap between the laboratory and epidemiological investigations. Environmental Health Perspectives. 55-67. PMID 8722110 DOI: 10.1289/Ehp.96104S155  0.301
1996 Guizzetti M, Costa P, Peters J, Costa LG. Acetylcholine as a mitogen: muscarinic receptor-mediated proliferation of rat astrocytes and human astrocytoma cells. European Journal of Pharmacology. 297: 265-73. PMID 8666059 DOI: 10.1016/0014-2999(95)00746-6  0.364
1996 Coccini T, Di Nucci A, Tonini M, Maestri L, Costa LG, Liuzzi M, Manzo L. Effects of ethanol administration on cerebral non-protein sulfhydryl content in rats exposed to styrene vapour Toxicology. 106: 115-122. PMID 8571382 DOI: 10.1016/0300-483X(95)03170-K  0.333
1995 Kovacs KA, Kavanagh TJ, Costa LG. Ethanol inhibits muscarinic receptor-stimulated phosphoinositide metabolism and calcium mobilization in rat primary cortical cultures Neurochemical Research. 20: 939-949. PMID 8587652 DOI: 10.1007/Bf00970740  0.355
1995 Costa LG, Deng H, Calleman CJ, Bergmark E. Evaluation of the neurotoxicity of glycidamide, an epoxide metabolite of acrylamide: behavioral, neurochemical and morphological studies. Toxicology. 98: 151-61. PMID 7740544 DOI: 10.1016/0300-483X(94)02986-5  0.349
1995 Tan XX, Costa LG. Postnatal development of muscarinic receptor-stimulated phosphoinositide metabolism in mouse cerebral cortex: sensitivity to ethanol. Brain Research. Developmental Brain Research. 86: 348-53. PMID 7656428 DOI: 10.1016/0165-3806(95)00024-8  0.358
1995 Candura SM, Tonini M, Baiardi P, Manzo L, Costa LG. Heterogeneity of cholinergic muscarinic receptors coupled to phosphoinositide metabolism in immature rat brain. Brain Research. Developmental Brain Research. 86: 134-42. PMID 7656406 DOI: 10.1016/0165-3806(95)00022-6  0.328
1995 Costa LG, Manzo L. Biochemical markers of neurotoxicity: research strategies and epidemiological applications. Toxicology Letters. 77: 137-44. PMID 7618127 DOI: 10.1016/0378-4274(95)03283-5  0.318
1995 Li WF, Furlong CE, Costa LG. Paraoxonase protects against chlorpyrifos toxicity in mice. Toxicology Letters. 76: 219-26. PMID 7539166 DOI: 10.1016/0378-4274(95)80006-Y  0.322
1995 Balduini W, Renò F, Costa LG. Interaction of ethanol and anoxia with muscarinic receptor--stimulated phosphoinositide metabolism during brain development. Life Sciences. 57: 1667-73. PMID 7475907 DOI: 10.1016/0024-3205(95)02146-A  0.372
1994 Balduini W, Reno F, Costa LG, Cattabeni F. Developmental neurotoxicity of ethanol: further evidence for an involvement of muscarinic receptor-stimulated phosphoinositide hydrolysis. European Journal of Pharmacology. 266: 283-9. PMID 8174611 DOI: 10.1016/0922-4106(94)90138-4  0.375
1994 Gregotti CF, Kirby Z, Manzo L, Costa LG, Faustman EM. Effects of styrene oxide on differentiation and viability of rodent embryo cultures. Toxicology and Applied Pharmacology. 128: 25-35. PMID 8079351 DOI: 10.1006/Taap.1994.1176  0.328
1994 Ehrich M, Intropido L, Costa LG. Interaction of organophosphorus compounds with muscarinic receptors in sh-sy5y human neuroblastoma cells Journal of Toxicology and Environmental Health. 43: 51-63. PMID 8078092 DOI: 10.1080/15287399409531903  0.302
1994 Tan XX, Costa LG. Inhibition of muscarinic receptor-stimulated phosphoinositide metabolism by cocaine, norcocaine and cocaethylene in rat brain. Brain Research. Developmental Brain Research. 79: 132-5. PMID 8070057 DOI: 10.1016/0165-3806(94)90057-4  0.302
1993 Fitzgerald BB, Costa LG. Modulation of muscarinic receptors and acetylcholinesterase activity in lymphocytes and in brain areas following repeated organophosphate exposure in rats. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 20: 210-6. PMID 8449393 DOI: 10.1006/Faat.1993.1028  0.353
1993 Tan XX, Castoldi AF, Manzo L, Costa LG. Interaction of ethanol with muscarinic receptor-stimulated phosphoinositide metabolism during the brain growth spurt in the rat: role of acetaldehyde. Neuroscience Letters. 156: 13-6. PMID 8414174 DOI: 10.1016/0304-3940(93)90427-M  0.374
1993 Castoldi AF, Manzo L, Costa LG. Cyclic GMP formation induced by muscarinic receptors is mediated by nitric oxide synthesis in rat cortical primary cultures. Brain Research. 610: 57-61. PMID 7686079 DOI: 10.1016/0006-8993(93)91216-F  0.347
1993 Candura SM, Castoldi AF, Manzo L, Costa LG. Guanine nucleotide- and muscarinic agonist-dependent phosphoinositide metabolism in synaptoneurosomes from cerebral cortex of immature rats. Neurochemical Research. 17: 1133-41. PMID 1361027 DOI: 10.1007/Bf00967291  0.348
1992 Calleman CJ, Bergmark E, Costa LG. Acrylamide is metabolized to glycidamide in the rat: evidence from hemoglobin adduct formation. Chemical Research in Toxicology. 3: 406-12. PMID 2133091 DOI: 10.1021/Tx00017A004  0.315
1992 Balduini W, Candura SM, Manzo L, Cattabeni F, Costa LG. Time-, concentration-, and age-dependent inhibition of muscarinic receptor-stimulated phosphoinositide metabolism by ethanol in the developing rat brain. Neurochemical Research. 16: 1235-40. PMID 1687696 DOI: 10.1007/Bf00966701  0.381
1992 Balduini W, Candura SM, Costa LG. Regional development of carbachol-, glutamate-, norepinephrine-, and serotonin-stimulated phosphoinositide metabolism in rat brain. Brain Research. Developmental Brain Research. 62: 115-20. PMID 1684740 DOI: 10.1016/0165-3806(91)90196-P  0.334
1992 Gregotti C, Di Nucci A, Costa LG, Manzo L, Scelsi R, Bertè F, Faustman EM. Effects of thallium on primary cultures of testicular cells. Journal of Toxicology and Environmental Health. 36: 59-69. PMID 1588638 DOI: 10.1080/15287399209531623  0.313
1992 Dypbukt JM, Costa LG, Manzo L, Orrenius S, Nicotera P. Cytotoxic and genotoxic effects of styrene-7,8-oxide in neuroadrenergic Pc 12 cells. Carcinogenesis. 13: 417-24. PMID 1547532 DOI: 10.1093/Carcin/13.3.417  0.315
1991 Balduini W, Costa LG. Characterization of ouabain-induced phosphoinositide hydrolysis in brain slices of the neonatal rat. Neurochemical Research. 15: 1023-9. PMID 1963925 DOI: 10.1007/Bf00965749  0.328
1991 Candura SM, Castoldi AF, Manzo L, Costa LG. Interaction of aluminum ions with phosphoinositide metabolism in rat cerebral cortical membranes. Life Sciences. 49: 1245-52. PMID 1943439 DOI: 10.1016/0024-3205(91)90137-Z  0.331
1991 Coccini T, Costa LG, Manzo L, Candura SM, Iapadre N, Balestra B, Tonini M. Two subtypes of enteric non-opioid sigma receptors in guinea-pig cholinergic motor neurons. European Journal of Pharmacology. 198: 105-8. PMID 1680712 DOI: 10.1016/0014-2999(91)90570-G  0.322
1990 Costa LG, Kaylor G, Murphy SD. In vitro and in vivo modulation of cholinergic muscarinic receptors in rat lymphocytes and brain by cholinergic agents International Journal of Immunopharmacology. 12: 67-75. PMID 2303319 DOI: 10.1016/0192-0561(90)90069-Y  0.333
1990 Candura SM, Coccini T, Manzo L, Costa LG. Interaction of sigma-compounds with receptor-stimulated phosphoinositide metabolism in the rat brain. Journal of Neurochemistry. 55: 1741-8. PMID 2170583 DOI: 10.1111/J.1471-4159.1990.Tb04964.X  0.322
1990 Costa LG. The phosphoinositide/protein kinase C system as a potential target for neurotoxicity Pharmacological Research. 22: 393-408. PMID 2169611 DOI: 10.1016/1043-6618(90)90747-2  0.312
1990 Balduini W, Costa LG. Developmental neurotoxicity of ethanol: in vitro inhibition of muscarinic receptor-stimulated phosphoinositide metabolism in brain from neonatal but not adult rats. Brain Research. 512: 248-52. PMID 2162233 DOI: 10.1016/0006-8993(90)90633-M  0.371
1990 Balduini W, Costa LG, Murphy SD. Potassium ions potentiate the muscarinic receptor-stimulated phosphoinositide metabolism in cerebral cortex slices: A comparison of neonatal and adult rats Neurochemical Research. 15: 33-39. PMID 2157990 DOI: 10.1007/Bf00969181  0.315
1990 Maier WE, Costa LG. Na+/K(+)-ATPase in rat brain and erythrocytes as a possible target and marker, respectively, for neurotoxicity: studies with chlordecone, organotins and mercury compounds. Toxicology Letters. 51: 175-88. PMID 1691869 DOI: 10.1016/0378-4274(90)90209-5  0.304
1990 Costa LG, McDonald BE, Murphy SD, Omenn GS, Richter RJ, Motulsky AG, Furlong CE. Serum paraoxonase and its influence on paraoxon and chlorpyrifos-oxon toxicity in rats. Toxicology and Applied Pharmacology. 103: 66-76. PMID 1690462 DOI: 10.1016/0041-008X(90)90263-T  0.318
1989 Costa LG, Wu DS, Olibet G, Murphy SD. Formamidine pesticides and alpha2-adrenoceptors: Studies with amitraz and chlordimeform in rats and development of a radioreceptor binding assay Neurotoxicology and Teratology. 11: 405-411. PMID 2552275 DOI: 10.1016/0892-0362(89)90014-7  0.322
1988 McDonald BE, Costa LG, Murphy SD. Spatial memory impairment and central muscarinic receptor loss following prolonged treatment with organophosphates. Toxicology Letters. 40: 47-56. PMID 3341049 DOI: 10.1016/0378-4274(88)90182-8  0.31
1988 Stamper CR, Balduini W, Murphy SD, Costa LG. Behavioral and biochemical effects of postnatal parathion exposure in the rat Neurotoxicology and Teratology. 10: 261-266. PMID 3211105 DOI: 10.1016/0892-0362(88)90026-8  0.302
1988 Costa LG. Interactions of neurotoxicants with neurotransmitter systems Toxicology. 49: 359-366. PMID 2897731 DOI: 10.1016/0300-483X(88)90019-4  0.344
1987 Janigro D, Costa LG. Effects of trimethyltin on granule cells excitability in the in vitro rat dentate gyrus. Neurotoxicology and Teratology. 9: 33-8. PMID 3041191 DOI: 10.1016/0892-0362(87)90067-5  0.315
1986 Costa LG, Sulaiman R. Inhibition of protein synthesis by trimethyltin. Toxicology and Applied Pharmacology. 86: 189-96. PMID 3787619 DOI: 10.1016/0041-008X(86)90049-9  0.303
1986 Costa LG, Murphy SD. Effect of diethylmaleate and other glutathione depletors on protein synthesis Biochemical Pharmacology. 35: 3383-3388. PMID 3768026 DOI: 10.1016/0006-2952(86)90439-9  0.319
1986 Roney PL, Costa LG, Murphy SD. Conditioned taste aversion induced by organophosphate compounds in rats. Pharmacology, Biochemistry, and Behavior. 24: 737-42. PMID 3703907 DOI: 10.1016/0091-3057(86)90583-6  0.303
1986 Costa LG, Kaylor G, Murphy SD. Interaction of choline with muscarine receptor-stimulated phosphoinositide metabolism in the rat brain Naunyn-Schmiedeberg's Archives of Pharmacology. 334: 536-539. PMID 3029607 DOI: 10.1007/Bf00569398  0.351
1984 Costa LG, Shao M, Basker K, Murphy SD. Chronic administration of an organophosphorus insecticide to rats alters cholinergic muscarinic receptors in the pancreas. Chemico-Biological Interactions. 48: 261-9. PMID 6609006 DOI: 10.1016/0009-2797(84)90139-X  0.334
1984 Costa LG, Murphy SD. Interaction of choline with nicotinic and muscarinic cholinergic receptors in the rat brain in vitro Clinical and Experimental Pharmacology and Physiology. 11: 649-654. PMID 6536422 DOI: 10.1111/J.1440-1681.1984.Tb00878.X  0.302
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