Christine Guthrie - Publications

Affiliations: 
Biochemistry University of California, San Francisco, San Francisco, CA 
Website:
http://www.jbc.org/content/285/1/1.full

153 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Antoine M, Patrick KL, Soret J, Duc P, Rage F, Cacciottolo R, Nissen KE, Cauchi RJ, Krogan NJ, Guthrie C, Gachet Y, Bordonné R. Splicing Defects of the Profilin Gene Alter Actin Dynamics in an S. pombe SMN Mutant. Iscience. 23: 100809. PMID 31927482 DOI: 10.1016/J.Isci.2019.100809  0.764
2019 Mayerle M, Yitiz S, Soulette C, Rogel LE, Ramirez A, Ragle JM, Katzman S, Guthrie C, Zahler AM. Prp8 impacts cryptic but not alternative splicing frequency. Proceedings of the National Academy of Sciences of the United States of America. PMID 30674666 DOI: 10.1073/Pnas.1819020116  0.488
2018 Kops AB, Burke JE, Guthrie C. Brr6 Plays a Role in Gene Recruitment and Transcriptional Regulation at the Nuclear envelope. Molecular Biology of the Cell. mbcE18040258. PMID 30133335 DOI: 10.1091/Mbc.E18-04-0258  0.45
2018 de Bruyn Kops A, Guthrie C. Identification of the Novel Allele in a Screen for Cold-Sensitive mRNA Export Mutants in . G3 (Bethesda, Md.). PMID 30021831 DOI: 10.1534/G3.118.200447  0.445
2018 MacRae AJ, Mayerle M, Hrabeta-Robinson E, Chalkley RJ, Guthrie C, Burlingame AL, Jurica M. Prp8 positioning of U5 snRNA is linked to 5' splice site recognition. Rna (New York, N.Y.). PMID 29487104 DOI: 10.1261/Rna.065458.117  0.472
2017 Nissen KE, Homer CM, Ryan CJ, Shales M, Krogan NJ, Patrick KL, Guthrie C. The histone variant H2A.Z promotes splicing of weak introns. Genes & Development. 31: 688-701. PMID 28446597 DOI: 10.1101/Gad.295287.116  0.801
2017 Mayerle M, Raghavan M, Ledoux S, Price A, Stepankiw N, Hadjivassiliou H, Moehle EA, Mendoza SD, Pleiss JA, Guthrie C, Abelson J. Structural toggle in the RNaseH domain of Prp8 helps balance splicing fidelity and catalytic efficiency. Proceedings of the National Academy of Sciences of the United States of America. PMID 28416677 DOI: 10.1073/Pnas.1701462114  0.795
2017 Mayerle M, Guthrie C. Genetics and Biochemistry Remain Essential in the Structural Era of the Spliceosome. Methods (San Diego, Calif.). PMID 28132896 DOI: 10.1016/J.Ymeth.2017.01.006  0.379
2016 Soucek S, Zeng Y, Bellur DL, Bergkessel M, Morris KJ, Deng Q, Duong D, Seyfried NT, Guthrie C, Staley JP, Fasken MB, Corbett AH. The Evolutionarily-conserved Polyadenosine RNA Binding Protein, Nab2, Cooperates with Splicing Machinery to Regulate the Fate of pre-mRNA. Molecular and Cellular Biology. PMID 27528618 DOI: 10.1128/Mcb.00402-16  0.842
2016 Ledoux S, Guthrie C. Retinitis Pigmentosa Mutations in Bad Response to Refrigeration 2 (Brr2) Impair ATPase and Helicase Activity. The Journal of Biological Chemistry. PMID 27072132 DOI: 10.1074/Jbc.M115.710848  0.444
2016 Mayerle M, Guthrie C. Prp8 retinitis pigmentosa mutants cause defects in the transition between the catalytic steps of splicing. Rna (New York, N.Y.). PMID 26968627 DOI: 10.1261/Rna.055459.115  0.479
2016 Mayerle M, Guthrie C. A new communication hub in the RNA world. Nature Structural & Molecular Biology. 23: 189-90. PMID 26931416 DOI: 10.1038/Nsmb.3178  0.404
2015 Holmes RK, Tuck AC, Zhu C, Dunn-Davies HR, Kudla G, Clauder-Munster S, Granneman S, Steinmetz LM, Guthrie C, Tollervey D. Loss of the Yeast SR Protein Npl3 Alters Gene Expression Due to Transcription Readthrough. Plos Genetics. 11: e1005735. PMID 26694144 DOI: 10.1371/Journal.Pgen.1005735  0.537
2015 Lipp JJ, Marvin MC, Shokat KM, Guthrie C. SR protein kinases promote splicing of nonconsensus introns. Nature Structural & Molecular Biology. 22: 611-7. PMID 26167880 DOI: 10.1038/Nsmb.3057  0.43
2015 Patrick KL, Ryan CJ, Xu J, Lipp JJ, Nissen KE, Roguev A, Shales M, Krogan NJ, Guthrie C. Genetic interaction mapping reveals a role for the SWI/SNF nucleosome remodeler in spliceosome activation in fission yeast. Plos Genetics. 11: e1005074. PMID 25825871 DOI: 10.1371/Journal.Pgen.1005074  0.822
2015 Guthrie C. Present at the creation. Rna (New York, N.Y.). 21: 481. PMID 25780103 DOI: 10.1261/Rna.049676.115  0.381
2014 Wang CQ, Guthrie C, Sarmast MK, Dehesh K. BBX19 interacts with CONSTANS to repress FLOWERING LOCUS T transcription, defining a flowering time checkpoint in Arabidopsis. The Plant Cell. 26: 3589-602. PMID 25228341 DOI: 10.1105/Tpc.114.130252  0.3
2014 Braberg H, Moehle EA, Shales M, Guthrie C, Krogan NJ. Genetic interaction analysis of point mutations enables interrogation of gene function at a residue-level resolution: exploring the applications of high-resolution genetic interaction mapping of point mutations. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 36: 706-13. PMID 24842270 DOI: 10.1002/Bies.201400044  0.747
2014 Moehle EA, Braberg H, Krogan NJ, Guthrie C. Adventures in time and space: splicing efficiency and RNA polymerase II elongation rate. Rna Biology. 11: 313-9. PMID 24717535 DOI: 10.4161/Rna.28646  0.789
2014 Hadjivassiliou H, Rosenberg OS, Guthrie C. The crystal structure of S. cerevisiae Sad1, a catalytically inactive deubiquitinase that is broadly required for pre-mRNA splicing Rna. 20: 656-669. PMID 24681967 DOI: 10.1261/Rna.042838.113  0.801
2014 Hérissant L, Moehle EA, Bertaccini D, Van Dorsselaer A, Schaeffer-Reiss C, Guthrie C, Dargemont C. H2B ubiquitylation modulates spliceosome assembly and function in budding yeast Biology of the Cell. 106: 126-138. PMID 24476359 DOI: 10.1111/Boc.201400003  0.78
2014 Price AM, Görnemann J, Guthrie C, Brow DA. An unanticipated early function of DEAD-box ATPase Prp28 during commitment to splicing is modulated by U5 snRNP protein Prp8. Rna (New York, N.Y.). 20: 46-60. PMID 24231520 DOI: 10.1261/Rna.041970.113  0.762
2014 Price AM, Görnemann J, Guthrie C, Brow DA. An unanticipated early function of DEAD-box ATPase Prp28 during commitment to splicing is modulated by U5 snRNP protein Prp8 Rna. 20: 46-60. DOI: 10.1261/rna.041970.113  0.694
2014 He Y, Wu S, Booth D, Agarrd D, Cheng Y, Guthrie C. Structural Studies of the Yeast Prp8-Snu114 Complex Biophysical Journal. 106: 47a. DOI: 10.1016/J.Bpj.2013.11.338  0.454
2014 Mayerle M, Abelson J, Guthrie C. Development of an smFRET Assay to Monitor Spliceosome Activation in Budding Yeast Biophysical Journal. 106: 496a. DOI: 10.1016/J.Bpj.2013.11.2774  0.393
2014 Ledoux S, Guthrie C. Characterization of Brr2 Helicase Activity on the U4/U6 snRNAs Biophysical Journal. 106: 496a. DOI: 10.1016/J.Bpj.2013.11.2773  0.392
2013 Krishnan R, Blanco MR, Kahlscheuer ML, Abelson J, Guthrie C, Walter NG. Biased Brownian ratcheting leads to pre-mRNA remodeling and capture prior to first-step splicing. Nature Structural & Molecular Biology. 20: 1450-7. PMID 24240612 DOI: 10.1038/Nsmb.2704  0.473
2013 Bergkessel M, Guthrie C, Abelson J. Yeast-gene replacement using PCR products Methods in Enzymology. 533: 43-55. PMID 24182917 DOI: 10.1016/B978-0-12-420067-8.00005-2  0.757
2013 Bergkessel M, Guthrie C. Chemical transformation of yeast Methods in Enzymology. 529: 311-320. PMID 24011057 DOI: 10.1016/B978-0-12-418687-3.00026-4  0.702
2013 Bergkessel M, Guthrie C. Colony PCR Methods in Enzymology. 529: 299-309. PMID 24011056 DOI: 10.1016/B978-0-12-418687-3.00025-2  0.716
2013 Braberg H, Jin H, Moehle EA, Chan YA, Wang S, Shales M, Benschop JJ, Morris JH, Qiu C, Hu F, Tang LK, Fraser JS, Holstege FC, Hieter P, Guthrie C, et al. From structure to systems: high-resolution, quantitative genetic analysis of RNA polymerase II. Cell. 154: 775-88. PMID 23932120 DOI: 10.1016/J.Cell.2013.07.033  0.791
2012 Moehle EA, Ryan CJ, Krogan NJ, Kress TL, Guthrie C. The yeast SR-like protein Npl3 links chromatin modification to mRNA processing. Plos Genetics. 8: e1003101. PMID 23209445 DOI: 10.1371/Journal.Pgen.1003101  0.808
2012 Ryan CJ, Roguev A, Patrick K, Xu J, Jahari H, Tong Z, Beltrao P, Shales M, Qu H, Collins SR, Kliegman JI, Jiang L, Kuo D, Tosti E, Kim HS, ... ... Guthrie C, et al. Hierarchical modularity and the evolution of genetic interactomes across species. Molecular Cell. 46: 691-704. PMID 22681890 DOI: 10.1016/J.Molcel.2012.05.028  0.74
2012 Plocik AM, Guthrie C. Diverse forms of RPS9 splicing are part of an evolving autoregulatory circuit. Plos Genetics. 8: e1002620. PMID 22479208 DOI: 10.1371/Journal.Pgen.1002620  0.815
2012 Moehle EA, Ryan CJ, Krogan NJ, Kress TL, Guthrie C. Extensive negative genetic interactions with npl3 Δ connect NPL3 to chromatin biology. Plos Genetics. DOI: 10.1371/Journal.Pgen.1003101.G001  0.709
2012 Plocik AM, Guthrie C. Diverse forms of RPS9 splicing are part of an evolving autoregulatory circuit Plos Genetics. 8. DOI: 10.1371/journal.pgen.1002620  0.734
2012 Blanco MR, Krishnan R, Kahlscheuer ML, Abelson J, Guthrie C, Walter NG. Single Molecule FRET Characterization of Pre-mRNA Splicing: Substrate Dynamics during Recognition and Catalysis Biophysical Journal. 102: 278a. DOI: 10.1016/J.Bpj.2011.11.1532  0.544
2011 Bergkessel M, Whitworth GB, Guthrie C. Diverse environmental stresses elicit distinct responses at the level of pre-mRNA processing in yeast Rna. 17: 1461-1478. PMID 21697354 DOI: 10.1261/Rna.2754011  0.807
2011 Ledoux S, Guthrie C. Regulation of the Dbp5 ATPase cycle in mRNP remodeling at the nuclear pore: A lively new paradigm for DEAD-box proteins Genes and Development. 25: 1109-1114. PMID 21632821 DOI: 10.1101/Gad.2062611  0.432
2010 Huff JT, Plocik AM, Guthrie C, Yamamoto KR. Reciprocal intronic and exonic histone modification regions in humans Nature Structural and Molecular Biology. 17: 1495-1499. PMID 21057525 DOI: 10.1038/Nsmb.1924  0.769
2010 Mitrovich QM, Tuch BB, De La Vega FM, Guthrie C, Johnson AD. Evolution of yeast noncoding RNAs reveals an alternative mechanism for widespread intron loss Science. 330: 838-841. PMID 21051641 DOI: 10.1126/Science.1194554  0.456
2010 Abelson J, Hadjivassiliou H, Guthrie C. Preparation of fluorescent pre-mRNA substrates for an smFRET study of pre-mRNA splicing in yeast. Methods in Enzymology. 472: 31-40. PMID 20580958 DOI: 10.1016/S0076-6879(10)72017-6  0.824
2010 Abelson J, Blanco M, Ditzler MA, Fuller F, Aravamudhan P, Wood M, Villa T, Ryan DE, Pleiss JA, Maeder C, Guthrie C, Walter NG. Conformational dynamics of single pre-mRNA molecules during in vitro splicing. Nature Structural & Molecular Biology. 17: 504-12. PMID 20305654 DOI: 10.1038/Nsmb.1767  0.828
2010 Guthrie C. From the ribosome to the spliceosome and back again. The Journal of Biological Chemistry. 285: 1-12. PMID 19880518 DOI: 10.1074/Jbc.X109.080580  0.369
2009 Zhang L, Xu T, Maeder C, Bud LO, Shanks J, Nix J, Guthrie C, Pleiss JA, Zhao R. Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2 Nature Structural and Molecular Biology. 16: 731-739. PMID 19525970 DOI: 10.1038/Nsmb.1625  0.794
2009 Bergkessel M, Wilmes GM, Guthrie C. SnapShot: Formation of mRNPs. Cell. 136: 794, 794.e1. PMID 19239896 DOI: 10.1016/J.Cell.2009.01.047  0.784
2009 Maeder C, Kutach AK, Guthrie C. ATP-dependent unwinding of U4/U6 snRNAs by the Brr2 helicase requires the C terminus of Prp8 Nature Structural and Molecular Biology. 16: 42-48. PMID 19098916 DOI: 10.1038/Nsmb.1535  0.673
2008 Wilmes GM, Bergkessel M, Bandyopadhyay S, Shales M, Braberg H, Cagney G, Collins SR, Whitworth GB, Kress TL, Weissman JS, Ideker T, Guthrie C, Krogan NJ. A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing. Molecular Cell. 32: 735-46. PMID 19061648 DOI: 10.1016/J.Molcel.2008.11.012  0.81
2008 Kress TL, Krogan NJ, Guthrie C. A single SR-like protein, Npl3, promotes pre-mRNA splicing in budding yeast. Molecular Cell. 32: 727-34. PMID 19061647 DOI: 10.1016/J.Molcel.2008.11.013  0.545
2008 Maeder C, Guthrie C. Modifications target spliceosome dynamics. Nature Structural & Molecular Biology. 15: 426-8. PMID 18461042 DOI: 10.1038/Nsmb0508-426  0.724
2008 Lund MK, Kress TL, Guthrie C. Autoregulation of Npl3, a yeast SR protein, requires a novel downstream region and serine phosphorylation. Molecular and Cellular Biology. 28: 3873-81. PMID 18391019 DOI: 10.1128/Mcb.02153-07  0.494
2007 Mitrovich QM, Guthrie C. Evolution of small nuclear RNAs in S. cerevisiae, C. albicans, and other hemiascomycetous yeasts. Rna (New York, N.Y.). 13: 2066-80. PMID 17956975 DOI: 10.1261/Rna.766607  0.476
2007 Pleiss JA, Whitworth GB, Bergkessel M, Guthrie C. Rapid, transcript-specific changes in splicing in response to environmental stress. Molecular Cell. 27: 928-37. PMID 17889666 DOI: 10.1016/J.Molcel.2007.07.018  0.804
2007 Pleiss JA, Whitworth GB, Bergkessel M, Guthrie C. Transcript specificity in yeast pre-mRNA splicing revealed by mutations in core spliceosomal components. Plos Biology. 5: e90. PMID 17388687 DOI: 10.1371/Journal.Pbio.0050090  0.831
2007 Mitrovich QM, Tuch BB, Guthrie C, Johnson AD. Computational and experimental approaches double the number of known introns in the pathogenic yeast Candida albicans. Genome Research. 17: 492-502. PMID 17351132 DOI: 10.1101/Gr.6111907  0.396
2007 Kim Guisbert KS, Li H, Guthrie C. Alternative 3' pre-mRNA processing in Saccharomyces cerevisiae is modulated by Nab4/Hrp1 in vivo. Plos Biology. 5: e6. PMID 17194212 DOI: 10.1371/Journal.Pbio.0050006  0.83
2006 Kress TL, Guthrie C. Molecular biology. Accurate RNA siting and splicing gets help from a DEK-hand. Science (New York, N.Y.). 312: 1886-7. PMID 16809518 DOI: 10.1126/Science.1130324  0.389
2006 Preker PJ, Guthrie C. Autoregulation of the mRNA export factor Yra1p requires inefficient splicing of its pre-mRNA. Rna (New York, N.Y.). 12: 994-1006. PMID 16618971 DOI: 10.1261/Rna.6706  0.543
2006 Brenner TJ, Guthrie C. Assembly of Snu114 into U5 snRNP requires Prp8 and a functional GTPase domain. Rna (New York, N.Y.). 12: 862-71. PMID 16540695 DOI: 10.1261/Rna.2319806  0.833
2006 Bellare P, Kutach AK, Rines AK, Guthrie C, Sontheimer EJ. Ubiquitin binding by a variant Jab1/MPN domain in the essential pre-mRNA splicing factor Prp8p. Rna (New York, N.Y.). 12: 292-302. PMID 16428608 DOI: 10.1261/Rna.2152306  0.489
2005 Lund MK, Guthrie C. The DEAD-box protein Dbp5p is required to dissociate Mex67p from exported mRNPs at the nuclear rim. Molecular Cell. 20: 645-51. PMID 16307927 DOI: 10.1016/J.Molcel.2005.10.005  0.493
2005 Villa T, Guthrie C. The Isy1p component of the NineTeen complex interacts with the ATPase Prp16p to regulate the fidelity of pre-mRNA splicing. Genes & Development. 19: 1894-904. PMID 16103217 DOI: 10.1101/Gad.1336305  0.474
2005 Brenner TJ, Guthrie C. Genetic analysis reveals a role for the C terminus of the Saccharomyces cerevisiae GTPase Snu114 during spliceosome activation. Genetics. 170: 1063-80. PMID 15911574 DOI: 10.1534/Genetics.105.042044  0.808
2005 Kim Guisbert K, Duncan K, Li H, Guthrie C. Functional specificity of shuttling hnRNPs revealed by genome-wide analysis of their RNA binding profiles. Rna (New York, N.Y.). 11: 383-93. PMID 15703440 DOI: 10.1261/Rna.7234205  0.831
2005 Guthrie C, Steitz J. Nucleus and gene expression: Coordinated nuclear events regulate mRNA synthesis, processing, export and turnover Current Opinion in Cell Biology. 17: 239-241. DOI: 10.1016/J.Ceb.2005.04.015  0.412
2004 Gilbert W, Guthrie C. The Glc7p nuclear phosphatase promotes mRNA export by facilitating association of Mex67p with mRNA. Molecular Cell. 13: 201-12. PMID 14759366 DOI: 10.1016/S1097-2765(04)00030-9  0.743
2004 Inada M, Guthrie C. Identification of Lhp1p-associated RNAs by microarray analysis in Saccharomyces cerevisiae reveals association with coding and noncoding RNAs. Proceedings of the National Academy of Sciences of the United States of America. 101: 434-9. PMID 14704279 DOI: 10.1073/Pnas.0307425100  0.689
2002 Rader SD, Guthrie C. A conserved Lsm-interaction motif in Prp24 required for efficient U4/U6 di-snRNP formation. Rna (New York, N.Y.). 8: 1378-92. PMID 12458792 DOI: 10.1017/S1355838202020010  0.451
2002 Preker PJ, Kim KS, Guthrie C. Expression of the essential mRNA export factor Yra1p is autoregulated by a splicing-dependent mechanism. Rna (New York, N.Y.). 8: 969-80. PMID 12212852 DOI: 10.1017/S1355838202020046  0.525
2002 Villa T, Pleiss JA, Guthrie C. Spliceosomal snRNAs: Mg(2+)-dependent chemistry at the catalytic core? Cell. 109: 149-52. PMID 12007401 DOI: 10.1016/S0092-8674(02)00726-2  0.729
2001 Collins CA, Guthrie C. Genetic interactions between the 5' and 3' splice site consensus sequences and U6 snRNA during the second catalytic step of pre-mRNA splicing. Rna (New York, N.Y.). 7: 1845-54. PMID 11780639  0.591
2001 de Bruyn Kops A, Guthrie C. An essential nuclear envelope integral membrane protein, Brr6p, required for nuclear transport. The Embo Journal. 20: 4183-93. PMID 11483521 DOI: 10.1093/Emboj/20.15.4183  0.354
2001 Gilbert W, Siebel CW, Guthrie C. Phosphorylation by Sky1p promotes Npl3p shuttling and mRNA dissociation. Rna (New York, N.Y.). 7: 302-13. PMID 11233987 DOI: 10.1017/S1355838201002369  0.695
2001 Kistler AL, Guthrie C. Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for sub2, an essential spliceosomal ATPase. Genes & Development. 15: 42-9. PMID 11156604 DOI: 10.1101/Gad.851301  0.669
2000 Collins CA, Guthrie C. The question remains: is the spliceosome a ribozyme? Nature Structural Biology. 7: 850-4. PMID 11017191 DOI: 10.1038/79598  0.649
2000 Duncan K, Umen JG, Guthrie C. A putative ubiquitin ligase required for efficient mRNA export differentially affects hnRNP transport. Current Biology : Cb. 10: 687-96. PMID 10873801 DOI: 10.1016/S0960-9822(00)00527-3  0.687
1999 Collins CA, Guthrie C. Allele-specific genetic interactions between Prp8 and RNA active site residues suggest a function for Prp8 at the catalytic core of the spliceosome. Genes & Development. 13: 1970-82. PMID 10444595 DOI: 10.1101/Gad.13.15.1970  0.649
1999 Siebel CW, Feng L, Guthrie C, Fu XD. Conservation in budding yeast of a kinase specific for SR splicing factors. Proceedings of the National Academy of Sciences of the United States of America. 96: 5440-5. PMID 10318902 DOI: 10.1073/Pnas.96.10.5440  0.426
1999 Staley JP, Guthrie C. An RNA switch at the 5' splice site requires ATP and the DEAD box protein Prp28p. Molecular Cell. 3: 55-64. PMID 10024879 DOI: 10.1016/S1097-2765(00)80174-4  0.669
1998 Raghunathan PL, Guthrie C. RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2. Current Biology : Cb. 8: 847-55. PMID 9705931 DOI: 10.1016/S0960-9822(07)00345-4  0.462
1998 Wang Y, Wagner JD, Guthrie C. The DEAH-box splicing factor Prp16 unwinds RNA duplexes in vitro. Current Biology : Cb. 8: 441-51. PMID 9550699 DOI: 10.1016/S0960-9822(98)70178-2  0.454
1998 Staley JP, Guthrie C. Mechanical devices of the spliceosome: motors, clocks, springs, and things. Cell. 92: 315-26. PMID 9476892 DOI: 10.1016/S0092-8674(00)80925-3  0.525
1998 Raghunathan PL, Guthrie C. A spliceosomal recycling factor that reanneals U4 and U6 small nuclear ribonucleoprotein particles. Science (New York, N.Y.). 279: 857-60. PMID 9452384 DOI: 10.1126/Science.279.5352.857  0.435
1997 Chanfreau G, Elela SA, Ares M, Guthrie C. Alternative 3'-end processing of U5 snRNA by RNase III Genes and Development. 11: 2741-2751. PMID 9334335 DOI: 10.1101/Gad.11.20.2741  0.708
1997 Stade K, Ford CS, Guthrie C, Weis K. Exportin 1 (Crm1p) is an essential nuclear export factor. Cell. 90: 1041-50. PMID 9323132 DOI: 10.1016/S0092-8674(00)80370-0  0.375
1996 Siebel CW, Guthrie C. The essential yeast RNA binding protein Np13p is methylated. Proceedings of the National Academy of Sciences of the United States of America. 93: 13641-6. PMID 8942987 DOI: 10.1073/Pnas.93.24.13641  0.418
1996 Chanfreau G, Noble SM, Guthrie C. Essential yeast protein with unexpected similarity to subunits of mammalian cleavage and polyadenylation specificity factor (CPSF) Science. 274: 1511-1514. PMID 8929408 DOI: 10.1126/Science.274.5292.1511  0.71
1996 Noble SM, Guthrie C. Transcriptional pulse-chase analysis reveals a role for a novel snRNP-associated protein in the manufacture of spliceosomal snRNPs. The Embo Journal. 15: 4368-79. PMID 8861964  0.361
1996 Noble SM, Guthrie C. Identification of novel genes required for yeast pre-mRNA splicing by means of cold-sensitive mutations. Genetics. 143: 67-80. PMID 8722763  0.399
1995 Umen JG, Guthrie C. The second catalytic step of pre-mRNA splicing. Rna (New York, N.Y.). 1: 869-85. PMID 8548652  0.307
1995 Jones MH, Frank DN, Guthrie C. Characterization and functional ordering of Slu7p and Prp17p during the second step of pre-mRNA splicing in yeast. Proceedings of the National Academy of Sciences of the United States of America. 92: 9687-91. PMID 7568198 DOI: 10.1073/Pnas.92.21.9687  0.47
1995 Umen JG, Guthrie C. A novel role for a U5 snRNP protein in 3' splice site selection. Genes & Development. 9: 855-68. PMID 7535718 DOI: 10.1101/Gad.9.7.855  0.46
1995 Umen JG, Guthrie C. Prp16p, Slu7p, and Prp8p interact with the 3' splice site in two distinct stages during the second catalytic step of pre-mRNA splicing. Rna (New York, N.Y.). 1: 584-97. PMID 7489518  0.302
1994 Lesser CF, Guthrie C. Mutations in U6 snRNA that alter splice site specificity: implications for the active site. Science (New York, N.Y.). 262: 1982-8. PMID 8266093 DOI: 10.1126/science.8266093  0.337
1994 Frank DN, Roiha H, Guthrie C. Architecture of the U5 small nuclear RNA. Molecular and Cellular Biology. 14: 2180-90. PMID 8114748 DOI: 10.1128/Mcb.14.3.2180  0.416
1994 Madhani HD, Guthrie C. Genetic interactions between the yeast RNA helicase homolog Prp16 and spliceosomal snRNAs identify candidate ligands for the Prp16 RNA-dependent ATPase. Genetics. 137: 677-87. PMID 8088513  0.417
1994 Madhani HD, Guthrie C. Randomization-selection analysis of snRNAs in vivo: evidence for a tertiary interaction in the spliceosome. Genes & Development. 8: 1071-86. PMID 7926788 DOI: 10.1101/Gad.8.9.1071  0.414
1994 Strauss EJ, Guthrie C. PRP28, a 'DEAD-box' protein, is required for the first step of mRNA splicing in vitro. Nucleic Acids Research. 22: 3187-93. PMID 7520570 DOI: 10.1093/Nar/22.15.3187  0.531
1993 Burgess SM, Guthrie C. A mechanism to enhance mRNA splicing fidelity: the RNA-dependent ATPase Prp16 governs usage of a discard pathway for aberrant lariat intermediates. Cell. 73: 1377-91. PMID 8324826 DOI: 10.1016/0092-8674(93)90363-U  0.401
1993 Burgess SM, Guthrie C. Beat the clock: paradigms for NTPases in the maintenance of biological fidelity Trends in Biochemical Sciences. 18: 381-384. PMID 8256287 DOI: 10.1016/0968-0004(93)90094-4  0.362
1992 Bordonné R, Guthrie C. Human and human-yeast chimeric U6 snRNA genes identify structural elements required for expression in yeast. Nucleic Acids Research. 20: 479-85. PMID 1741282 DOI: 10.1093/Nar/20.3.479  0.415
1992 Frank D, Guthrie C. An essential splicing factor, SLU7, mediates 3' splice site choice in yeast. Genes & Development. 6: 2112-24. PMID 1427075 DOI: 10.1101/Gad.6.11.2112  0.504
1992 Frank D, Patterson B, Guthrie C. Synthetic lethal mutations suggest interactions between U5 small nuclear RNA and four proteins required for the second step of splicing. Molecular and Cellular Biology. 12: 5197-205. PMID 1406691 DOI: 10.1128/Mcb.12.11.5197  0.487
1992 Schwer B, Guthrie C. A dominant negative mutation in a spliceosomal ATPase affects ATP hydrolysis but not binding to the spliceosome Molecular and Cellular Biology. 12: 3540-3547. PMID 1385854 DOI: 10.1128/Mcb.12.8.3540  0.442
1992 Schwer B, Guthrie C. A conformational rearrangement in the spliceosome is dependent on PRP16 and ATP hydrolysis. The Embo Journal. 11: 5033-5039. DOI: 10.1002/J.1460-2075.1992.Tb05610.X  0.353
1991 Strauss EJ, Guthrie C. A cold-sensitive mRNA splicing mutant is a member of the RNA helicase gene family. Genes & Development. 5: 629-41. PMID 2010088 DOI: 10.1101/gad.5.4.629  0.43
1991 Guthrie C. Messenger RNA splicing in yeast: clues to why the spliceosome is a ribonucleoprotein. Science (New York, N.Y.). 253: 157-63. PMID 1853200 DOI: 10.1126/science.1853200  0.353
1991 Patterson B, Guthrie C. A U-rich tract enhances usage of an alternative 3' splice site in yeast. Cell. 64: 181-7. PMID 1846089 DOI: 10.1016/0092-8674(91)90219-O  0.43
1991 Siliciano PG, Kivens WJ, Guthrie C. More than half of yeast U1 snRNA is dispensable for growth. Nucleic Acids Research. 19: 6367-6372. PMID 1754372 DOI: 10.1093/Nar/19.23.6367  0.45
1990 Roiha H, Shuster EO, Brow DA, Guthrie C. Small nuclear RNAs from budding yeasts: phylogenetic comparisons reveal extensive size variation. Gene. 82: 137-44. PMID 2684769 DOI: 10.1016/0378-1119(89)90038-3  0.459
1990 Brow DA, Guthrie C. Transcription of a yeast U6 snRNA gene requires a polymerase III promoter element in a novel position. Genes & Development. 4: 1345-56. PMID 2227412 DOI: 10.1101/Gad.4.8.1345  0.464
1990 Shuster EO, Guthrie C. Human U2 snRNA can function in pre-mRNA splicing in yeast. Nature. 345: 270-3. PMID 2185425 DOI: 10.1038/345270A0  0.531
1990 Bordonné R, Banroques J, Abelson J, Guthrie C. Domains of yeast U4 spliceosomal RNA required for PRP4 protein binding, snRNP-snRNP interactions, and pre-mRNA splicing in vivo. Genes & Development. 4: 1185-96. PMID 2145195 DOI: 10.1101/Gad.4.7.1185  0.454
1990 Guthrie C, Shannon K, Bordonne R. Genetic dissection of the U4/U6/U5 snRNP "cycle' in yeast Molecular Biology Reports. 14: 139-140. PMID 2141896 DOI: 10.1007/Bf00360448  0.307
1990 Burgess S, Couto JR, Guthrie C. A putative ATP binding protein influences the fidelity of branchpoint recognition in yeast splicing. Cell. 60: 705-17. PMID 2138057 DOI: 10.1016/0092-8674(90)90086-T  0.348
1990 Jones MH, Guthrie C. Unexpected flexibility in an evolutionarily conserved protein-RNA interaction: genetic analysis of the Sm binding site. The Embo Journal. 9: 2555-2561. DOI: 10.1002/J.1460-2075.1990.Tb07436.X  0.497
1989 Siliciano PG, Guthrie C. 5' splice site selection in yeast: genetic alterations in base-pairing with U1 reveal additional requirements. Genes & Development. 2: 1258-67. PMID 3060402 DOI: 10.1101/Gad.2.10.1258  0.325
1989 Brow DA, Guthrie C. Splicing a spliceosomal RNA. Nature. 337: 14-5. PMID 2909888 DOI: 10.1038/337014A0  0.396
1988 Shuster EO, Guthrie C. Two conserved domains of yeast U2 snRNA are separated by 945 nonessential nucleotides. Cell. 55: 41-8. PMID 3048702 DOI: 10.1016/0092-8674(88)90007-4  0.377
1988 Brow DA, Guthrie C. Spliceosomal RNA U6 is remarkably conserved from yeast to mammals. Nature. 334: 213-8. PMID 3041282 DOI: 10.1038/334213a0  0.383
1988 Parker R, Simmons T, Shuster EO, Siliciano PG, Guthrie C. Genetic analysis of small nuclear RNAs in Saccharomyces cerevisiae: viable sextuple mutant. Molecular and Cellular Biology. 8: 3150-9. PMID 2905424 DOI: 10.1128/Mcb.8.8.3150  0.641
1987 Patterson B, Guthrie C. An essential yeast snRNA with a U5-like domain is required for splicing in vivo. Cell. 49: 613-24. PMID 3555841 DOI: 10.1016/0092-8674(87)90537-X  0.416
1987 Parker R, Siliciano PG, Guthrie C. Recognition of the TACTAAC box during mRNA splicing in yeast involves base pairing to the U2-like snRNA. Cell. 49: 229-39. PMID 3552247 DOI: 10.1016/0092-8674(87)90564-2  0.563
1987 Siliciano PG, Jones MH, Guthrie C. Saccharomyces cerevisiae has a Ul-like small nuclear RNA with unexpected properties Science. 237: 1484-1487. PMID 3306922 DOI: 10.1126/Science.3306922  0.348
1987 Riedel N, Wolin S, Guthrie C. A subset of yeast snRNA's contains functional binding sites for the highly conserved Sm antigen Science. 235: 328-331. PMID 2948278 DOI: 10.1126/Science.2948278  0.392
1987 Couto JR, Tamm J, Parker R, Guthrie C. A trans-acting suppressor restores splicing of a yeast intron with a branch point mutation. Genes & Development. 1: 445-55. PMID 2890553 DOI: 10.1101/Gad.1.5.445  0.597
1987 Siliciano PG, Brow DA, Roiha H, Guthrie C. An essential snRNA from S. cerevisiae has properties predicted for U4, including interaction with a U6-like snRNA. Cell. 50: 585-92. PMID 2440583 DOI: 10.1016/0092-8674(87)90031-6  0.331
1986 Riedel N, Wise JA, Swerdlow H, Mak A, Guthrie C. Small nuclear RNAs from Saccharomyces cerevisiae: unexpected diversity in abundance, size, and molecular complexity. Proceedings of the National Academy of Sciences of the United States of America. 83: 8097-101. PMID 3534883 DOI: 10.1073/Pnas.83.21.8097  0.635
1986 Cellini A, Parker R, McMahon J, Guthrie C, Rossi J. Activation of a cryptic TACTAAC box in the Saccharomyces cerevisiae actin intron. Molecular and Cellular Biology. 6: 1571-8. PMID 3023896 DOI: 10.1128/Mcb.6.5.1571  0.525
1986 Vijayraghavan U, Parker R, Tamm J, Iimura Y, Rossi J, Abelson J, Guthrie C. Mutations in conserved intron sequences affect multiple steps in the yeast splicing pathway, particularly assembly of the spliceosome. The Embo Journal. 5: 1683-95. PMID 3017708  0.561
1986 Guthrie C. Finding functions for small nuclear RNAs in yeast Trends in Biochemical Sciences. 11: 430-434. DOI: 10.1016/0968-0004(86)90179-9  0.452
1985 Parker R, Guthrie C. A point mutation in the conserved hexanucleotide at a yeast 5' splice junction uncouples recognition, cleavage, and ligation. Cell. 41: 107-18. PMID 2986840 DOI: 10.1016/0092-8674(85)90065-0  0.556
1985 Tollervey D, Guthrie C. Deletion of a yeast small nuclear RNA gene impairs growth. The Embo Journal. 4: 3873-3878. DOI: 10.1002/J.1460-2075.1985.Tb04160.X  0.416
1983 Tollervey D, Wise JA, Guthrie C. A U4-like small nuclear RNA is dispensable in yeast. Cell. 35: 753-62. PMID 6197184 DOI: 10.1016/0092-8674(83)90108-3  0.681
1982 Etcheverry T, Salvato M, Guthrie C. Recessive lethality of yeast strains carrying the SUP61 suppressor results from loss of a transfer RNA with a unique decoding function. Journal of Molecular Biology. 158: 599-618. PMID 6750138 DOI: 10.1016/0022-2836(82)90251-0  0.352
1982 Guthrie C, Abelson J. Organization and Expression of tRNA Genes in Saccharomyces cerevisiae Cold Spring Harbor Monograph Archive. 487-528. DOI: 10.1101/087969180.11B.487  0.454
1981 Guthrie C, Scholla CA. Asymmetric maturation of a dimeric transfer RNA precursor. Journal of Molecular Biology. 139: 349-75. PMID 7441739 DOI: 10.1016/0022-2836(80)90135-7  0.373
1981 Guthrie C. Folding up a transfer RNA molecule is not simple. The Quarterly Review of Biology. 55: 335-52. PMID 7022545 DOI: 10.1086/411979  0.315
1981 Colby D, Leboy PS, Guthrie C. Yeast tRNA precursor mutated at a splice junction is correctly processed in vivo. Proceedings of the National Academy of Sciences of the United States of America. 78: 415-9. PMID 7017715 DOI: 10.1073/Pnas.78.1.415  0.455
1979 Guthrie C, McClain WH. Rare transfer ribonucleic acid essential for phage growth. Nucleotide sequence comparison of normal and mutant T4 isoleucine-accepting transfer ribonucleic acid. Biochemistry. 18: 3786-95. PMID 476088 DOI: 10.1021/Bi00584A023  0.351
1979 Etcheverry T, Colby D, Guthrie C. A precursor to a minor species of yeast tRNASer contains an intervening sequence Cell. 18: 11-26. PMID 389430 DOI: 10.1016/0092-8674(79)90349-0  0.344
1979 Manale A, Guthrie C, Colby D. S1 nuclease as a probe for the conformation of a dimeric tRNA precursor. Biochemistry. 18: 77-83. PMID 369598 DOI: 10.1021/Bi00568A012  0.342
1978 Guthrie C, Scholla CA, Yesian H, Abelson J. The nucleotide sequence of threonine transfer RNA coded by bacteriophage T4. Nucleic Acids Research. 5: 1833-44. PMID 353731 DOI: 10.1093/Nar/5.6.1833  0.375
1977 Colby DS, Schedl P, Guthrie C. A functional requirement for modification of the wobble nucleotide in tha anticodon of a T4 suppressor tRNA. Cell. 9: 449-63. PMID 791507 DOI: 10.1016/0092-8674(76)90090-8  0.407
1975 Guthrie C. The nucleotide sequence of the dimeric precursor to glutamine and leucine transfer RNAs coded by bacteriophage T4. Journal of Molecular Biology. 95: 529-47. PMID 1097716 DOI: 10.1016/0022-2836(75)90315-0  0.346
1974 Comer MM, Guthrie C, McClain WH. An ochre suppressor of bacteriophage T4 that is associated with a transfer RNA. Journal of Molecular Biology. 90: 665-76. PMID 4615176 DOI: 10.1016/0022-2836(74)90531-2  0.303
1974 Barrell BG, Seidman JG, Guthrie C, McClain WH. Transfer RNA biosynthesis: the nucleotide sequence of a precursor to serine and proline transfer RNAs. Proceedings of the National Academy of Sciences of the United States of America. 71: 413-6. PMID 4521813 DOI: 10.1073/Pnas.71.2.413  0.36
1973 McClain WH, Guthrie C, Barrell BG. Eight transfer RNAs induced by infection of Escherichia coli with bacteriophage T4. Proceedings of the National Academy of Sciences of the United States of America. 69: 3703-7. PMID 4566457 DOI: 10.1073/Pnas.69.12.3703  0.325
1969 Guthrie C, Nashimoto H, Nomura M. Studies on the assembly of ribosomes in vivo. Cold Spring Harbor Symposia On Quantitative Biology. 34: 69-75. PMID 4909525  0.467
1969 Nomura M, Traub P, Guthrie C, Nashimoto H. The assembly of ribosomes. Journal of Cellular Physiology. 74: Suppl 1:241+. PMID 4902821  0.46
1969 Guthrie C, Nashimoto H, Nomura M. Structure and function of E. coli ribosomes. 8. Cold-sensitive mutants defective in ribosome assembly. Proceedings of the National Academy of Sciences of the United States of America. 63: 384-91. PMID 4895536 DOI: 10.1073/Pnas.63.2.384  0.55
1968 Guthrie C, Nomura M. Initiation of protein synthesis: a critical test of the 30S subunit model. Nature. 219: 232-5. PMID 4876464  0.443
1967 Nomura M, Lowry CV, Guthrie C. The initiation of protein synthesis: joining of the 50S ribosomal subunit to the initiation complex. Proceedings of the National Academy of Sciences of the United States of America. 58: 1487-93. PMID 4867661  0.473
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