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Gregory S. Shelness - Publications

Affiliations: 
Wake Forest University, Winston-Salem, NC, United States 
Area:
Virology Biology, Microbiology Biology, Molecular Biology
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45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Liu M, Chung S, Shelness GS, Parks JS. Hepatic ABCA1 deficiency is associated with delayed apolipoprotein B secretory trafficking and augmented VLDL triglyceride secretion. Biochimica Et Biophysica Acta. PMID 28694219 DOI: 10.1016/J.Bbalip.2017.07.001  0.532
2017 Tsai TH, Chen E, Li L, Saha P, Lee HJ, Huang LS, Shelness GS, Chan L, Chang BH. The Constitutive Lipid Droplet Protein Plin2 Regulates Autophagy in Liver. Autophagy. 0. PMID 28548876 DOI: 10.1080/15548627.2017.1319544  0.475
2016 Cheng D, Xu X, Simon T, Boudyguina E, Deng Z, VerHague M, Lee AH, Shelness GS, Weinberg RB, Parks JS. Very low density lipoprotein assembly is required for cAMP responsive element-binding protein H processing and hepatic apolipoprotein A-IV expression. The Journal of Biological Chemistry. PMID 27655915 DOI: 10.1074/Jbc.M116.749283  0.445
2015 Weckerle A, Snipes JA, Cheng D, Gebre AK, Reisz JA, Murea M, Shelness GS, Hawkins GA, Furdui CM, Freedman BI, Parks JS, Ma L. Characterization of circulating APOL1 protein complexes in African Americans. Journal of Lipid Research. PMID 26586272 DOI: 10.1194/Jlr.M063453  0.327
2015 Cheng D, Weckerle A, Yu Y, Ma L, Zhu X, Murea M, Freedman BI, Parks JS, Shelness GS. Biogenesis and cytotoxicity of APOL1 renal-risk variant proteins in hepatocytes and hepatoma cells. Journal of Lipid Research. PMID 26089538 DOI: 10.1194/Jlr.M059733  0.346
2015 Liu M, Allegood J, Zhu X, Seo J, Gebre AK, Boudyguina E, Cheng D, Chuang CC, Shelness GS, Spiegel S, Parks JS. Uncleaved ApoM signal peptide is required for formation of large ApoM/sphingosine 1-phosphate (S1P)-enriched HDL particles. The Journal of Biological Chemistry. 290: 7861-70. PMID 25627684 DOI: 10.1074/Jbc.M114.631101  0.421
2015 Ma L, Shelness GS, Snipes JA, Murea M, Antinozzi PA, Cheng D, Saleem MA, Satchell SC, Banas B, Mathieson PW, Kretzler M, Hemal AK, Rudel LL, Petrovic S, Weckerle A, et al. Localization of APOL1 protein and mRNA in the human kidney: nondiseased tissue, primary cells, and immortalized cell lines. Journal of the American Society of Nephrology : Jasn. 26: 339-48. PMID 25012173 DOI: 10.1681/Asn.2013091017  0.309
2014 Liu M, Seo J, Allegood J, Bi X, Zhu X, Boudyguina E, Gebre AK, Avni D, Shah D, Sorci-Thomas MG, Thomas MJ, Shelness GS, Spiegel S, Parks JS. Hepatic apolipoprotein M (apoM) overexpression stimulates formation of larger apoM/sphingosine 1-phosphate-enriched plasma high density lipoprotein. The Journal of Biological Chemistry. 289: 2801-14. PMID 24318881 DOI: 10.1074/Jbc.M113.499913  0.459
2013 Verhague MA, Cheng D, Weinberg RB, Shelness GS. Apolipoprotein A-IV expression in mouse liver enhances triglyceride secretion and reduces hepatic lipid content by promoting very low density lipoprotein particle expansion Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 2501-2508. PMID 24030551 DOI: 10.1161/Atvbaha.113.301948  0.489
2012 Avraham-Davidi I, Ely Y, Pham VN, Castranova D, Grunspan M, Malkinson G, Gibbs-Bar L, Mayseless O, Allmog G, Lo B, Warren CM, Chen TT, Ungos J, Kidd K, Shaw K, ... ... Shelness GS, et al. ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1. Nature Medicine. 18: 967-73. PMID 22581286 DOI: 10.1038/Nm.2759  0.402
2012 Parks JS, Chung S, Shelness GS. Hepatic ABC transporters and triglyceride metabolism. Current Opinion in Lipidology. 23: 196-200. PMID 22488425 DOI: 10.1097/Mol.0B013E328352Dd1A  0.488
2012 Weinberg RB, Gallagher JW, Fabritius MA, Shelness GS. ApoA-IV modulates the secretory trafficking of apoB and the size of triglyceride-rich lipoproteins. Journal of Lipid Research. 53: 736-43. PMID 22257482 DOI: 10.1194/Jlr.M019992  0.506
2012 Khatun I, Zeissig S, Iqbal J, Wang M, Curiel D, Shelness GS, Blumberg RS, Hussain MM. Phospholipid transfer activity of microsomal triglyceride transfer protein produces apolipoprotein B and reduces hepatosteatosis while maintaining low plasma lipids in mice. Hepatology (Baltimore, Md.). 55: 1356-68. PMID 22121032 DOI: 10.1002/Hep.25504  0.515
2012 Liu M, Chung S, Shelness GS, Parks JS. Hepatic ABCA1 and VLDL triglyceride production. Biochimica Et Biophysica Acta. 1821: 770-7. PMID 22001232 DOI: 10.1016/J.Bbalip.2011.09.020  0.53
2011 Blade AM, Fabritius MA, Hou L, Weinberg RB, Shelness GS. Biogenesis of apolipoprotein A-V and its impact on VLDL triglyceride secretion. Journal of Lipid Research. 52: 237-44. PMID 21115968 DOI: 10.1194/Jlr.M010793  0.445
2010 Chung S, Gebre AK, Seo J, Shelness GS, Parks JS. A novel role for ABCA1-generated large pre-beta migrating nascent HDL in the regulation of hepatic VLDL triglyceride secretion. Journal of Lipid Research. 51: 729-42. PMID 20215580 DOI: 10.1194/Jlr.M900083  0.508
2010 Chung S, Timmins JM, Duong M, Degirolamo C, Rong S, Sawyer JK, Singaraja RR, Hayden MR, Maeda N, Rudel LL, Shelness GS, Parks JS. Targeted deletion of hepatocyte ABCA1 leads to very low density lipoprotein triglyceride overproduction and low density lipoprotein hypercatabolism. The Journal of Biological Chemistry. 285: 12197-209. PMID 20178985 DOI: 10.1074/Jbc.M109.096933  0.489
2010 Cheng D, MacArthur PS, Rong S, Parks JS, Shelness GS. Alternative splicing attenuates transgenic expression directed by the apolipoprotein E promoter-enhancer based expression vector pLIV11. Journal of Lipid Research. 51: 849-55. PMID 19965599 DOI: 10.1194/Jlr.D002709  0.3
2010 Mulya A, Seo J, Brown AL, Gebre AK, Boudyguina E, Shelness GS, Parks JS. Apolipoprotein M expression increases the size of nascent pre beta HDL formed by ATP binding cassette transporter A1. Journal of Lipid Research. 51: 514-24. PMID 19767535 DOI: 10.1194/Jlr.M002162  0.558
2009 Degirolamo C, Shelness GS, Rudel LL. LDL cholesteryl oleate as a predictor for atherosclerosis: evidence from human and animal studies on dietary fat. Journal of Lipid Research. 50: S434-9. PMID 19029117 DOI: 10.1194/Jlr.R800076-Jlr200  0.464
2009 Ledford AS, Cook VA, Shelness GS, Weinberg RB. Structural and dynamic interfacial properties of the lipoprotein initiating domain of apolipoprotein B. Journal of Lipid Research. 50: 108-15. PMID 18711207 DOI: 10.1194/Jlr.M800324-Jlr200  0.37
2007 Brown JM, Chung S, Das A, Shelness GS, Rudel LL, Yu L. CGI-58 facilitates the mobilization of cytoplasmic triglyceride for lipoprotein secretion in hepatoma cells. Journal of Lipid Research. 48: 2295-305. PMID 17664529 DOI: 10.1194/Jlr.M700279-Jlr200  0.489
2007 Mohler PJ, Zhu MY, Blade AM, Ham AJL, Shelness GS, Swift LL. Identification of a novel isoform of microsomal triglyceride transfer protein Journal of Biological Chemistry. 282: 26981-26988. PMID 17635917 DOI: 10.1074/Jbc.M700500200  0.48
2007 Temel RE, Hou L, Rudel LL, Shelness GS. ACAT2 stimulates cholesteryl ester secretion in apoB-containing lipoproteins. Journal of Lipid Research. 48: 1618-27. PMID 17438337 DOI: 10.1194/Jlr.M700109-Jlr200  0.509
2006 Rava P, Ojakian GK, Shelness GS, Hussain MM. Phospholipid transfer activity of microsomal triacylglycerol transfer protein is sufficient for the assembly and secretion of apolipoprotein B lipoproteins. The Journal of Biological Chemistry. 281: 11019-27. PMID 16478722 DOI: 10.1074/Jbc.M512823200  0.478
2006 Ledford AS, Weinberg RB, Cook VR, Hantgan RR, Shelness GS. Self-association and lipid binding properties of the lipoprotein initiating domain of apolipoprotein B. The Journal of Biological Chemistry. 281: 8871-6. PMID 16407215 DOI: 10.1074/Jbc.M507657200  0.423
2006 Lu S, Yao Y, Cheng X, Mitchell S, Leng S, Meng S, Gallagher JW, Shelness GS, Morris GS, Mahan J, Frase S, Mansbach CM, Weinberg RB, Black DD. Overexpression of apolipoprotein A-IV enhances lipid secretion in IPEC-1 cells by increasing chylomicron size. The Journal of Biological Chemistry. 281: 3473-83. PMID 16338933 DOI: 10.1074/Jbc.M502501200  0.499
2005 Shelness GS, Rudel LL. A role for the pregnane X receptor in high-density lipoprotein metabolism. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 2016-7. PMID 16199756 DOI: 10.1161/01.Atv.0000186042.94668.2B  0.528
2005 Shelness GS, Ledford AS. Evolution and mechanism of apolipoprotein B-containing lipoprotein assembly. Current Opinion in Lipidology. 16: 325-32. PMID 15891394 DOI: 10.1097/01.Mol.0000169353.12772.Eb  0.47
2005 Shoulders CC, Shelness GS. Current biology of MTP: implications for selective inhibition. Current Topics in Medicinal Chemistry. 5: 283-300. PMID 15857311  0.375
2005 Sellers JA, Hou L, Schoenberg DR, Batistuzzo de Medeiros SR, Wahli W, Shelness GS. Microsomal triglyceride transfer protein promotes the secretion of Xenopus laevis vitellogenin A1. The Journal of Biological Chemistry. 280: 13902-5. PMID 15701598 DOI: 10.1074/Jbc.M500769200  0.391
2004 Gallagher JW, Weinberg RB, Shelness GS. apoA-IV tagged with the ER retention signal KDEL perturbs the intracellular trafficking and secretion of apoB. Journal of Lipid Research. 45: 1826-34. PMID 15258202 DOI: 10.1194/Jlr.M400188-Jlr200  0.495
2004 Bhat S, Zabalawi M, Willingham MC, Shelness GS, Thomas MJ, Sorci-Thomas MG. Quality control in the apoA-I secretory pathway: deletion of apoA-I helix 6 leads to the formation of cytosolic phospholipid inclusions. Journal of Lipid Research. 45: 1207-20. PMID 15060083 DOI: 10.1194/Jlr.M300498-Jlr200  0.452
2003 Shelness GS, Hou L, Ledford AS, Parks JS, Weinberg RB. Identification of the lipoprotein initiating domain of apolipoprotein B. The Journal of Biological Chemistry. 278: 44702-7. PMID 12941937 DOI: 10.1074/Jbc.M307562200  0.508
2003 Weinberg RB, Cook VR, Beckstead JA, Martin DD, Gallagher JW, Shelness GS, Ryan RO. Structure and interfacial properties of human apolipoprotein A-V. The Journal of Biological Chemistry. 278: 34438-44. PMID 12810715 DOI: 10.1074/Jbc.M303784200  0.393
2003 Sellers JA, Hou L, Athar H, Hussain MM, Shelness GS. A Drosophila microsomal triglyceride transfer protein homolog promotes the assembly and secretion of human apolipoprotein B. Implications for human and insect transport and metabolism. The Journal of Biological Chemistry. 278: 20367-73. PMID 12657646 DOI: 10.1074/Jbc.M300271200  0.49
2002 Chisholm JW, Burleson ER, Shelness GS, Parks JS. ApoA-I secretion from HepG2 cells: evidence for the secretion of both lipid-poor apoA-I and intracellularly assembled nascent HDL. Journal of Lipid Research. 43: 36-44. PMID 11792720  0.411
2001 Shelness GS, Sellers JA. Very-low-density lipoprotein assembly and secretion Current Opinion in Lipidology. 12: 151-157. PMID 11264986 DOI: 10.1097/00041433-200104000-00008  0.504
2000 Rudel LL, Shelness GS. Cholesterol esters and atherosclerosis-a game of ACAT and mouse. Nature Medicine. 6: 1313-4. PMID 11100106 DOI: 10.1038/82110  0.448
2000 Joyce CW, Shelness GS, Davis MA, Lee RG, Skinner K, Anderson RA, Rudel LL. ACAT1 and ACAT2 membrane topology segregates a serine residue essential for activity to opposite sides of the endoplasmic reticulum membrane. Molecular Biology of the Cell. 11: 3675-87. PMID 11071899 DOI: 10.1091/Mbc.11.11.3675  0.418
2000 Reagan JW, Hubbert ML, Shelness GS. Posttranslational Regulation of Acid Sphingomyelinase in Niemann-Pick Type C1 Fibroblasts and Free Cholesterol-enriched Chinese Hamster Ovary Cells Journal of Biological Chemistry. 275: 38104-38110. PMID 10978332 DOI: 10.1074/Jbc.M005296200  0.46
1999 Shelness GS, Ingram MF, Huang XF, DeLozier JA. Apolipoprotein B in the Rough Endoplasmic Reticulum: Translation, Translocation and the Initiation of Lipoprotein Assembly Journal of Nutrition. 129: 456-462. PMID 10064309 DOI: 10.1093/Jn/129.2.456S  0.505
1998 Anderson RA, Joyce C, Davis M, Reagan JW, Clark M, Shelness GS, Rudel LL. Identification of a form of acyl-CoA:cholesterol acyltransferase specific to liver and intestine in nonhuman primates. The Journal of Biological Chemistry. 273: 26747-54. PMID 9756918 DOI: 10.1074/Jbc.273.41.26747  0.428
1997 Huang XF, Shelness GS. Identification of Cysteine Pairs within the Amino-terminal 5% of Apolipoprotein B Essential for Hepatic Lipoprotein Assembly and Secretion Journal of Biological Chemistry. 272: 31872-31876. PMID 9395534 DOI: 10.1074/Jbc.272.50.31872  0.436
1997 Ingram MF, Shelness GS. Folding of the Amino-terminal Domain of Apolipoprotein B Initiates Microsomal Triglyceride Transfer Protein-dependent Lipid Transfer to Nascent Very Low Density Lipoprotein Journal of Biological Chemistry. 272: 10279-10286. PMID 9092579 DOI: 10.1074/Jbc.272.15.10279  0.519
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