Peter J. Mohler, Ph.D. - Publications

University of North Carolina, Chapel Hill, Chapel Hill, NC 

164 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Li N, Csepe TA, Hansen BJ, Sul LV, Kalyanasundaram A, Zakharkin SO, Zhao J, Guha A, Van Wagoner DR, Kilic A, Mohler PJ, Janssen PM, Biesiadecki B, Hummel JD, Weiss R, et al. Adenosine-Induced Atrial Fibrillation: Localized Reentrant Drivers in Lateral Right Atria due to Heterogeneous Expression of Adenosine A1 Receptors and GIRK4 Subunits in the Human Heart. Circulation. PMID 27462069 DOI: 10.1161/Circulationaha.115.021165  0.8
2016 Milani-Nejad N, Chung JH, Canan BD, Davis JP, Fedorov VV, Higgins RS, Kilic A, Mohler PJ, Janssen PM. Insights into Length-Dependent Regulation of Cardiac Cross-Bridge Cycling kinetics in Human Myocardium. Archives of Biochemistry and Biophysics. PMID 26854725 DOI: 10.1016/J.Abb.2016.02.005  0.8
2016 Yue T, Park KH, Reese BE, Zhu H, Lyon S, Ma J, Mohler PJ, Zhang M. Quantifying Drug-induced Nano-mechanics and Mechanical Effects to Single Cardiomyocytes for Optimal Drug Administration to Minimize Cardiotoxicity. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 26738425 DOI: 10.1021/Acs.Langmuir.5B04314  0.8
2015 Zhao J, Hansen BJ, Csepe TA, Lim P, Wang Y, Williams M, Mohler PJ, Janssen PM, Weiss R, Hummel JD, Fedorov VV. Integration of High-Resolution Optical Mapping and 3-Dimensional Micro-Computed Tomographic Imaging to Resolve the Structural Basis of Atrial Conduction in the Human Heart. Circulation. Arrhythmia and Electrophysiology. 8: 1514-7. PMID 26671938 DOI: 10.1161/Circep.115.003064  0.8
2015 Laganà A, Veneziano D, Spata T, Tang R, Zhu H, Mohler PJ, Kilic A. Identification of General and Heart-Specific miRNAs in Sheep (Ovis aries). Plos One. 10: e0143313. PMID 26599010 DOI: 10.1371/Journal.Pone.0143313  0.8
2015 Milani-Nejad N, Canan BD, Elnakish MT, Davis JP, Chung JH, Fedorov V, Binkley PF, Higgins RS, Kilic A, Mohler PJ, Janssen PM. The Frank-Starling Mechanism Involves Deceleration of Cross-Bridge Kinetics and is Preserved in Failing Human Right Ventricular Myocardium. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00685.2015. PMID 26453335 DOI: 10.1152/Ajpheart.00685.2015  0.8
2015 Roof SR, Boslett J, Russell D, Del Rio C, Alecusan J, Zweier JL, Ziolo MT, Hamlin R, Mohler PJ, Curran J. Insulin-like growth factor 1 prevents diastolic and systolic dysfunction associated with cardiomyopathy and preserves adrenergic sensitivity. Acta Physiologica (Oxford, England). PMID 26399932 DOI: 10.1111/Apha.12607  0.8
2015 Musa H, Kline CF, Sturm AC, Murphy N, Adelman S, Wang C, Yan H, Johnson BL, Csepe TA, Kilic A, Higgins RS, Janssen PM, Fedorov VV, Weiss R, Salazar C, ... ... Mohler PJ, et al. SCN5A variant that blocks fibroblast growth factor homologous factor regulation causes human arrhythmia. Proceedings of the National Academy of Sciences of the United States of America. 112: 12528-33. PMID 26392562 DOI: 10.1073/Pnas.1516430112  0.8
2015 Li N, Csepe TA, Hansen BJ, Dobrzynski H, Higgins RS, Kilic A, Mohler PJ, Janssen PM, Rosen MR, Biesiadecki BJ, Fedorov VV. Molecular Mapping of Sinoatrial Node HCN Channel Expression in the Human Heart. Circulation. Arrhythmia and Electrophysiology. PMID 26304511 DOI: 10.1161/Circep.115.003070  0.8
2015 Love JD, Suzuki T, Robinson DB, Harris CM, Johnson JE, Mohler PJ, Jerome WG, Swift LL. Microsomal Triglyceride Transfer Protein (MTP) Associates with Cytosolic Lipid Droplets in 3T3-L1 Adipocytes. Plos One. 10: e0135598. PMID 26267806 DOI: 10.1371/Journal.Pone.0135598  0.8
2015 Little SC, Curran J, Makara MA, Kline CF, Ho HT, Xu Z, Wu X, Polina I, Musa H, Meadows AM, Carnes CA, Biesiadecki BJ, Davis JP, Weisleder N, Györke S, ... ... Mohler PJ, et al. Protein phosphatase 2A regulatory subunit B56α limits phosphatase activity in the heart. Science Signaling. 8: ra72. PMID 26198358 DOI: 10.1126/Scisignal.Aaa5876  0.8
2015 Glynn P, Musa H, Wu X, Unudurthi SD, Little S, Qian L, Wright PJ, Radwanski PB, Gyorke S, Mohler PJ, Hund TJ. Voltage-Gated Sodium Channel Phosphorylation at Ser571 Regulates Late Current, Arrhythmia, and Cardiac Function in vivo. Circulation. PMID 26187182 DOI: 10.1161/Circulationaha.114.015218  0.8
2015 Neshatian L, Strege PR, Rhee PL, Kraichely RE, Mazzone A, Bernard CE, Cima RR, Larson DW, Dozois EJ, Kline CF, Mohler PJ, Beyder A, Farrugia G. Ranolazine inhibits voltage-gated mechanosensitive sodium channels in human colon circular smooth muscle cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 309: G506-12. PMID 26185330 DOI: 10.1152/Ajpgi.00051.2015  0.8
2015 Elnakish MT, Ahmed AA, Mohler PJ, Janssen PM. Role of Oxidative Stress in Thyroid Hormone-Induced Cardiomyocyte Hypertrophy and Associated Cardiac Dysfunction: An Undisclosed Story. Oxidative Medicine and Cellular Longevity. 2015: 854265. PMID 26146529 DOI: 10.1155/2015/854265  0.8
2015 Hansen BJ, Zhao J, Csepe TA, Moore BT, Li N, Jayne LA, Kalyanasundaram A, Lim P, Bratasz A, Powell KA, Simonetti OP, Higgins RS, Kilic A, Mohler PJ, Janssen PM, et al. Atrial fibrillation driven by micro-anatomic intramural re-entry revealed by simultaneous sub-epicardial and sub-endocardial optical mapping in explanted human hearts. European Heart Journal. PMID 26059724 DOI: 10.1093/Eurheartj/Ehv233  0.8
2015 Curran J, Musa H, Kline CF, Makara MA, Little SC, Higgins JD, Hund TJ, Band H, Mohler PJ. Eps15 Homology Domain-containing Protein 3 Regulates Cardiac T-type Ca2+ Channel Targeting and Function in the Atria. The Journal of Biological Chemistry. 290: 12210-21. PMID 25825486 DOI: 10.1074/Jbc.M115.646893  0.8
2015 Elnakish MT, Schultz EJ, Gearinger RL, Saad NS, Rastogi N, Ahmed AA, Mohler PJ, Janssen PM. Differential involvement of various sources of reactive oxygen species in thyroxin-induced hemodynamic changes and contractile dysfunction of the heart and diaphragm muscles. Free Radical Biology & Medicine. 83: 252-61. PMID 25795514 DOI: 10.1016/J.Freeradbiomed.2015.02.035  0.8
2015 Duann P, Li H, Lin P, Tan T, Wang Z, Chen K, Zhou X, Gumpper K, Zhu H, Ludwig T, Mohler PJ, Rovin B, Abraham WT, Zeng C, Ma J. MG53-mediated cell membrane repair protects against acute kidney injury. Science Translational Medicine. 7: 279ra36. PMID 25787762 DOI: 10.1126/Scitranslmed.3010755  0.8
2015 Chen-Izu Y, Shaw RM, Pitt GS, Yarov-Yarovoy V, Sack JT, Abriel H, Aldrich RW, Belardinelli L, Cannell MB, Catterall WA, Chazin WJ, Chiamvimonvat N, Deschenes I, Grandi E, Hund TJ, ... ... Mohler PJ, et al. Na+ channel function, regulation, structure, trafficking and sequestration. The Journal of Physiology. 593: 1347-60. PMID 25772290 DOI: 10.1113/Jphysiol.2014.281428  0.8
2015 Billman GE, Cagnoli KL, Csepe T, Li N, Wright P, Mohler PJ, Fedorov VV. Exercise training-induced bradycardia: evidence for enhanced parasympathetic regulation without changes in intrinsic sinoatrial node function. Journal of Applied Physiology (Bethesda, Md. : 1985). 118: 1344-55. PMID 25749448 DOI: 10.1152/Japplphysiol.01111.2014  0.8
2015 Curran J, Makara MA, Mohler PJ. Endosome-based protein trafficking and Ca(2+) homeostasis in the heart. Frontiers in Physiology. 6: 34. PMID 25709583 DOI: 10.3389/Fphys.2015.00034  0.8
2015 Smith SA, Sturm AC, Curran J, Kline CF, Little SC, Bonilla IM, Long VP, Makara M, Polina I, Hughes LD, Webb TR, Wei Z, Wright P, Voigt N, Bhakta D, ... ... Mohler PJ, et al. Dysfunction in the βII spectrin-dependent cytoskeleton underlies human arrhythmia. Circulation. 131: 695-708. PMID 25632041 DOI: 10.1161/Circulationaha.114.013708  0.8
2015 Long VP, Bonilla IM, Vargas-Pinto P, Nishijima Y, Sridhar A, Li C, Mowrey K, Wright P, Velayutham M, Kumar S, Lee NY, Zweier JL, Mohler PJ, Györke S, Carnes CA. Heart failure duration progressively modulates the arrhythmia substrate through structural and electrical remodeling. Life Sciences. 123: 61-71. PMID 25596015 DOI: 10.1016/J.Lfs.2014.12.024  0.8
2015 Hund TJ, Mohler PJ. Role of CaMKII in cardiac arrhythmias. Trends in Cardiovascular Medicine. 25: 392-397. PMID 25577293 DOI: 10.1016/J.Tcm.2014.12.001  0.8
2015 Radwa?ski PB, Brunello L, Veeraraghavan R, Ho HT, Lou Q, Makara MA, Belevych AE, Anghelescu M, Priori SG, Volpe P, Hund TJ, Janssen PM, Mohler PJ, Bridge JH, Poelzing S, et al. Neuronal Na+ channel blockade suppresses arrhythmogenic diastolic Ca2+ release. Cardiovascular Research. 106: 143-52. PMID 25538156 DOI: 10.1093/Cvr/Cvu262  0.8
2015 Swager SA, Delfín DA, Rastogi N, Wang H, Canan BD, Fedorov VV, Mohler PJ, Kilic A, Higgins RS, Ziolo MT, Janssen PM, Rafael-Fortney JA. Claudin-5 levels are reduced from multiple cell types in human failing hearts and are associated with mislocalization of ephrin-B1. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 24: 160-7. PMID 25440958 DOI: 10.1016/J.Carpath.2014.10.006  0.8
2015 Ziolo MT, Mohler PJ. Defining the role of oxidative stress in atrial fibrillation and diabetes. Journal of Cardiovascular Electrophysiology. 26: 223-5. PMID 25298131 DOI: 10.1111/Jce.12560  0.8
2015 Curran J, Mohler PJ. Alternative paradigms for ion channelopathies: disorders of ion channel membrane trafficking and posttranslational modification. Annual Review of Physiology. 77: 505-24. PMID 25293528 DOI: 10.1146/Annurev-Physiol-021014-071838  0.8
2015 Glukhov AV, Kalyanasundaram A, Lou Q, Hage LT, Hansen BJ, Belevych AE, Mohler PJ, Knollmann BC, Periasamy M, Györke S, Fedorov VV. Calsequestrin 2 deletion causes sinoatrial node dysfunction and atrial arrhythmias associated with altered sarcoplasmic reticulum calcium cycling and degenerative fibrosis within the mouse atrial pacemaker complex1. European Heart Journal. 36: 686-97. PMID 24216388 DOI: 10.1093/Eurheartj/Eht452  0.8
2015 Grueter CE, Abiria SA, Dzhura I, Wu Y, Ham AJL, Mohler PJ, Anderson ME, Colbran RJ. Retraction Notice To: L-Type Ca2+ Channel Facilitation Mediated by Phosphorylation of the β Subunit by CaMKII [Molecular Cell 23 (2006) 641-650] Molecular Cell. 58: 388. DOI: 10.1016/J.Molcel.2015.04.007  0.8
2014 Chang KJ, Zollinger DR, Susuki K, Sherman DL, Makara MA, Brophy PJ, Cooper EC, Bennett V, Mohler PJ, Rasband MN. Glial ankyrins facilitate paranodal axoglial junction assembly. Nature Neuroscience. 17: 1673-81. PMID 25362471 DOI: 10.1038/Nn.3858  0.8
2014 Bonilla IM, Long VP, Vargas-Pinto P, Wright P, Belevych A, Lou Q, Mowrey K, Yoo J, Binkley PF, Fedorov VV, Györke S, Janssen PM, Kilic A, Mohler PJ, Carnes CA. Calcium-activated potassium current modulates ventricular repolarization in chronic heart failure. Plos One. 9: e108824. PMID 25271970 DOI: 10.1371/Journal.Pone.0108824  0.8
2014 Joiner ML, Koval OM, Li J, He BJ, Allamargot C, Gao Z, Luczak ED, Hall DD, Fink BD, Chen B, Yang J, Moore SA, Scholz TD, Strack S, Mohler PJ, et al. Joiner et al. reply. Nature. 513: E3. PMID 25254481 DOI: 10.1038/Nature13627  0.8
2014 Makara MA, Curran J, Little SC, Musa H, Polina I, Smith SA, Wright PJ, Unudurthi SD, Snyder J, Bennett V, Hund TJ, Mohler PJ. Ankyrin-G coordinates intercalated disc signaling platform to regulate cardiac excitability in vivo. Circulation Research. 115: 929-38. PMID 25239140 DOI: 10.1161/Circresaha.115.305154  0.8
2014 Dun W, Wright P, Danilo P, Mohler PJ, Boyden PA. SAP97 and cortactin remodeling in arrhythmogenic Purkinje cells. Plos One. 9: e106830. PMID 25184222 DOI: 10.1371/Journal.Pone.0106830  0.8
2014 Hund TJ, Mohler PJ. Nav channel complex heterogeneity: new targets for the treatment of arrhythmia? Circulation. 130: 132-4. PMID 24895456 DOI: 10.1161/Circulationaha.114.010867  0.8
2014 Lou Q, Hansen BJ, Fedorenko O, Csepe TA, Kalyanasundaram A, Li N, Hage LT, Glukhov AV, Billman GE, Weiss R, Mohler PJ, Györke S, Biesiadecki BJ, Carnes CA, Fedorov VV. Upregulation of adenosine A1 receptors facilitates sinoatrial node dysfunction in chronic canine heart failure by exacerbating nodal conduction abnormalities revealed by novel dual-sided intramural optical mapping. Circulation. 130: 315-24. PMID 24838362 DOI: 10.1161/Circulationaha.113.007086  0.8
2014 Dybkova N, Wagner S, Backs J, Hund TJ, Mohler PJ, Sowa T, Nikolaev VO, Maier LS. Tubulin polymerization disrupts cardiac β-adrenergic regulation of late INa. Cardiovascular Research. 103: 168-77. PMID 24812278 DOI: 10.1093/Cvr/Cvu120  0.8
2014 Curran J, Makara MA, Little SC, Musa H, Liu B, Wu X, Polina I, Alecusan JS, Wright P, Li J, Billman GE, Boyden PA, Gyorke S, Band H, Hund TJ, ... Mohler PJ, et al. EHD3-dependent endosome pathway regulates cardiac membrane excitability and physiology. Circulation Research. 115: 68-78. PMID 24759929 DOI: 10.1161/Circresaha.115.304149  0.8
2014 Moldovan L, Anghelina M, Kantor T, Jones D, Ramadan E, Xiang Y, Huang K, Kolipaka A, Malarkey W, Ghasemzadeh N, Mohler PJ, Quyyumi A, Moldovan NI. A module of human peripheral blood mononuclear cell transcriptional network containing primitive and differentiation markers is related to specific cardiovascular health variables. Plos One. 9: e95124. PMID 24759906 DOI: 10.1371/Journal.Pone.0095124  0.8
2014 Vreeker A, van Stuijvenberg L, Hund TJ, Mohler PJ, Nikkels PG, van Veen TA. Assembly of the cardiac intercalated disk during pre- and postnatal development of the human heart. Plos One. 9: e94722. PMID 24733085 DOI: 10.1371/Journal.Pone.0094722  0.8
2014 Curran J, Tang L, Roof SR, Velmurugan S, Millard A, Shonts S, Wang H, Santiago D, Ahmad U, Perryman M, Bers DM, Mohler PJ, Ziolo MT, Shannon TR. Nitric oxide-dependent activation of CaMKII increases diastolic sarcoplasmic reticulum calcium release in cardiac myocytes in response to adrenergic stimulation. Plos One. 9: e87495. PMID 24498331 DOI: 10.1371/Journal.Pone.0087495  0.8
2014 Hund TJ, Snyder JS, Wu X, Glynn P, Koval OM, Onal B, Leymaster ND, Unudurthi SD, Curran J, Camardo C, Wright PJ, Binkley PF, Anderson ME, Mohler PJ. β(IV)-Spectrin regulates TREK-1 membrane targeting in the heart. Cardiovascular Research. 102: 166-75. PMID 24445605 DOI: 10.1093/Cvr/Cvu008  0.8
2014 Barry J, Gu Y, Jukkola P, O'Neill B, Gu H, Mohler PJ, Rajamani KT, Gu C. Ankyrin-G directly binds to kinesin-1 to transport voltage-gated Na+ channels into axons. Developmental Cell. 28: 117-31. PMID 24412576 DOI: 10.1016/J.Devcel.2013.11.023  0.8
2014 Kline CF, Scott J, Curran J, Hund TJ, Mohler PJ. Ankyrin-B regulates Cav2.1 and Cav2.2 channel expression and targeting. The Journal of Biological Chemistry. 289: 5285-95. PMID 24394417 DOI: 10.1074/Jbc.M113.523639  0.8
2014 Kline CF, Mohler PJ. Defective interactions of protein partner with ion channels and transporters as alternative mechanisms of membrane channelopathies. Biochimica Et Biophysica Acta. 1838: 723-30. PMID 23732236 DOI: 10.1016/J.Bbamem.2013.05.024  0.8
2014 Wang Y, Dakhlallah D, Moldovan L, Anderson T, Ezzie M, Nana-Sinkam SP, Mohler PJ, Trgovich J, Cook C, Piper MG, Marsh CB. Circulating MicroRNAs as Biomarkers Microrna in Regenerative Medicine. 1093-1125. DOI: 10.1016/B978-0-12-405544-5.00042-3  0.8
2014 Hund TJ, Smith SA, Makara MA, Mohler PJ. Cellular and Molecular Pathobiology of the Cardiac Conduction System Cellular and Molecular Pathobiology of Cardiovascular Disease. 121-134. DOI: 10.1016/B978-0-12-405206-2.00007-7  0.8
2013 Spata T, Bobek D, Whitson BA, Parthasarathy S, Mohler PJ, Higgins RS, Kilic A. A nonthoracotomy myocardial infarction model in an ovine using autologous platelets. Biomed Research International. 2013: 938047. PMID 24367790 DOI: 10.1155/2013/938047  0.8
2013 Kline CF, Mohler PJ. Evolving form to fit function: cardiomyocyte intercalated disc and transverse-tubule membranes. Current Topics in Membranes. 72: 121-58. PMID 24210429 DOI: 10.1016/B978-0-12-417027-8.00004-0  0.8
2013 Dun W, Lowe JS, Wright P, Hund TJ, Mohler PJ, Boyden PA. Ankyrin-G participates in INa remodeling in myocytes from the border zones of infarcted canine heart. Plos One. 8: e78087. PMID 24155982 DOI: 10.1371/Journal.Pone.0078087  0.8
2013 Kline CF, Wright PJ, Koval OM, Zmuda EJ, Johnson BL, Anderson ME, Hai T, Hund TJ, Mohler PJ. βIV-Spectrin and CaMKII facilitate Kir6.2 regulation in pancreatic beta cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 17576-81. PMID 24101510 DOI: 10.1073/Pnas.1314195110  0.8
2013 Little SC, Mohler PJ. TRPM4 modulates sinus node diastolic depolarization. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 10: 1690-1. PMID 23988696 DOI: 10.1016/J.Hrthm.2013.08.026  0.8
2013 Sanders PN, Koval OM, Jaffer OA, Prasad AM, Businga TR, Scott JA, Hayden PJ, Luczak ED, Dickey DD, Allamargot C, Olivier AK, Meyerholz DK, Robison AJ, Winder DG, Blackwell TS, ... ... Mohler PJ, et al. CaMKII is essential for the proasthmatic effects of oxidation. Science Translational Medicine. 5: 195ra97. PMID 23884469 DOI: 10.1126/Scitranslmed.3006135  0.8
2013 Curran J, Mohler PJ. Revisiting K(+) channel-dependent electrical remodeling in the border zone. Journal of Cardiovascular Electrophysiology. 24: 1154-6. PMID 23773490 DOI: 10.1111/Jce.12189  0.8
2013 Toischer K, Hartmann N, Wagner S, Fischer TH, Herting J, Danner BC, Sag CM, Hund TJ, Mohler PJ, Belardinelli L, Hasenfuss G, Maier LS, Sossalla S. Role of late sodium current as a potential arrhythmogenic mechanism in the progression of pressure-induced heart disease. Journal of Molecular and Cellular Cardiology. 61: 111-22. PMID 23570977 DOI: 10.1016/J.Yjmcc.2013.03.021  0.8
2013 Lübkemeier I, Requardt RP, Lin X, Sasse P, Andrié R, Schrickel JW, Chkourko H, Bukauskas FF, Kim JS, Frank M, Malan D, Zhang J, Wirth A, Dobrowolski R, Mohler PJ, et al. Deletion of the last five C-terminal amino acid residues of connexin43 leads to lethal ventricular arrhythmias in mice without affecting coupling via gap junction channels. Basic Research in Cardiology. 108: 348. PMID 23558439 DOI: 10.1007/S00395-013-0348-Y  0.8
2013 Zhang W, Zhao S, Rao W, Snyder J, Choi JK, Wang J, Khan IA, Saleh NB, Mohler PJ, Yu J, Hund TJ, Tang C, He X. A Novel Core-Shell Microcapsule for Encapsulation and 3D Culture of Embryonic Stem Cells. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 2013: 1002-1009. PMID 23505611 DOI: 10.1039/C2Tb00058J  0.8
2013 Wolf RM, Glynn P, Hashemi S, Zarei K, Mitchell CC, Anderson ME, Mohler PJ, Hund TJ. Atrial fibrillation and sinus node dysfunction in human ankyrin-B syndrome: a computational analysis. American Journal of Physiology. Heart and Circulatory Physiology. 304: H1253-66. PMID 23436330 DOI: 10.1152/Ajpheart.00734.2012  0.8
2013 Sierra A, Zhu Z, Sapay N, Sharotri V, Kline CF, Luczak ED, Subbotina E, Sivaprasadarao A, Snyder PM, Mohler PJ, Anderson ME, Vivaudou M, Zingman LV, Hodgson-Zingman DM. Regulation of cardiac ATP-sensitive potassium channel surface expression by calcium/calmodulin-dependent protein kinase II. The Journal of Biological Chemistry. 288: 1568-81. PMID 23223335 DOI: 10.1074/Jbc.M112.429548  0.8
2013 DeGrande ST, Little SC, Nixon DJ, Wright P, Snyder J, Dun W, Murphy N, Kilic A, Higgins R, Binkley PF, Boyden PA, Carnes CA, Anderson ME, Hund TJ, Mohler PJ. Molecular mechanisms underlying cardiac protein phosphatase 2A regulation in heart. The Journal of Biological Chemistry. 288: 1032-46. PMID 23204520 DOI: 10.1074/Jbc.M112.426957  0.8
2013 Noorman M, Hakim S, Kessler E, Groeneweg JA, Cox MG, Asimaki A, van Rijen HV, van Stuijvenberg L, Chkourko H, van der Heyden MA, Vos MA, de Jonge N, van der Smagt JJ, Dooijes D, Vink A, ... ... Mohler PJ, et al. Remodeling of the cardiac sodium channel, connexin43, and plakoglobin at the intercalated disk in patients with arrhythmogenic cardiomyopathy. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 10: 412-9. PMID 23178689 DOI: 10.1016/J.Hrthm.2012.11.018  0.8
2013 Yamankurt G, Nguyen FT, Mohler PJ, Cunha SR. Ankyrin-based trafficking and scaffolding of membrane proteins: Implications for plasma membrane stability, formation, and specialization Journal of Proteomics and Bioinformatics. 6. DOI: 10.4172/Jpb.1000284  0.8
2013 Hund TJ, Mohler PJ. Biophysics of Normal and Abnormal Cardiac Sodium Channel Function Cardiac Electrophysiology: From Cell to Bedside: Sixth Edition. 95-101. DOI: 10.1016/B978-1-4557-2856-5.00009-1  0.8
2012 Curran J, Mohler PJ. Defining the pathways underlying the prolonged PR interval in atrioventricular conduction disease. Plos Genetics. 8: e1003154. PMID 23236297 DOI: 10.1371/Journal.Pgen.1003154  0.8
2012 DeGrande S, Nixon D, Koval O, Curran JW, Wright P, Wang Q, Kashef F, Chiang D, Li N, Wehrens XH, Anderson ME, Hund TJ, Mohler PJ. CaMKII inhibition rescues proarrhythmic phenotypes in the model of human ankyrin-B syndrome. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 9: 2034-41. PMID 23059182 DOI: 10.1016/J.Hrthm.2012.08.026  0.8
2012 Joiner ML, Koval OM, Li J, He BJ, Allamargot C, Gao Z, Luczak ED, Hall DD, Fink BD, Chen B, Yang J, Moore SA, Scholz TD, Strack S, Mohler PJ, et al. CaMKII determines mitochondrial stress responses in heart. Nature. 491: 269-73. PMID 23051746 DOI: 10.1038/Nature11444  0.8
2012 Koval OM, Snyder JS, Wolf RM, Pavlovicz RE, Glynn P, Curran J, Leymaster ND, Dun W, Wright PJ, Cardona N, Qian L, Mitchell CC, Boyden PA, Binkley PF, Li C, ... ... Mohler PJ, et al. Ca2+/calmodulin-dependent protein kinase II-based regulation of voltage-gated Na+ channel in cardiac disease. Circulation. 126: 2084-94. PMID 23008441 DOI: 10.1161/Circulationaha.112.105320  0.8
2012 Kashef F, Li J, Wright P, Snyder J, Suliman F, Kilic A, Higgins RS, Anderson ME, Binkley PF, Hund TJ, Mohler PJ. Ankyrin-B protein in heart failure: identification of a new component of metazoan cardioprotection. The Journal of Biological Chemistry. 287: 30268-81. PMID 22778271 DOI: 10.1074/Jbc.M112.368415  0.8
2012 Cerrone M, Noorman M, Lin X, Chkourko H, Liang FX, van der Nagel R, Hund T, Birchmeier W, Mohler P, van Veen TA, van Rijen HV, Delmar M. Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency. Cardiovascular Research. 95: 460-8. PMID 22764151 DOI: 10.1093/Cvr/Cvs218  0.8
2012 Galiano MR, Jha S, Ho TS, Zhang C, Ogawa Y, Chang KJ, Stankewich MC, Mohler PJ, Rasband MN. A distal axonal cytoskeleton forms an intra-axonal boundary that controls axon initial segment assembly. Cell. 149: 1125-39. PMID 22632975 DOI: 10.1016/J.Cell.2012.03.039  0.8
2012 Smith S, Curran J, Hund TJ, Mohler PJ. Defects in cytoskeletal signaling pathways, arrhythmia, and sudden cardiac death. Frontiers in Physiology. 3: 122. PMID 22586405 DOI: 10.3389/Fphys.2012.00122  0.8
2012 Camors E, Mohler PJ, Bers DM, Despa S. Ankyrin-B reduction enhances Ca spark-mediated SR Ca release promoting cardiac myocyte arrhythmic activity. Journal of Molecular and Cellular Cardiology. 52: 1240-8. PMID 22406428 DOI: 10.1016/J.Yjmcc.2012.02.010  0.8
2012 Gudmundsson H, Curran J, Kashef F, Snyder JS, Smith SA, Vargas-Pinto P, Bonilla IM, Weiss RM, Anderson ME, Binkley P, Felder RB, Carnes CA, Band H, Hund TJ, Mohler PJ. Differential regulation of EHD3 in human and mammalian heart failure. Journal of Molecular and Cellular Cardiology. 52: 1183-90. PMID 22406195 DOI: 10.1016/J.Yjmcc.2012.02.008  0.8
2012 Wheeler DG, Joseph ME, Mahamud SD, Aurand WL, Mohler PJ, Pompili VJ, Dwyer KM, Nottle MB, Harrison SJ, d'Apice AJ, Robson SC, Cowan PJ, Gumina RJ. Transgenic swine: expression of human CD39 protects against myocardial injury. Journal of Molecular and Cellular Cardiology. 52: 958-61. PMID 22269791 DOI: 10.1016/J.Yjmcc.2012.01.002  0.8
2012 Jansen JA, Noorman M, Musa H, Stein M, de Jong S, van der Nagel R, Hund TJ, Mohler PJ, Vos MA, van Veen TA, de Bakker JM, Delmar M, van Rijen HV. Reduced heterogeneous expression of Cx43 results in decreased Nav1.5 expression and reduced sodium current that accounts for arrhythmia vulnerability in conditional Cx43 knockout mice. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 9: 600-7. PMID 22100711 DOI: 10.1016/J.Hrthm.2011.11.025  0.8
2011 Liu Y, Chen H, Ji G, Li B, Mohler PJ, Zhu Z, Yong W, Chen Z, Xu X, Xin H, Shou W. Transgenic analysis of the role of FKBP12.6 in cardiac function and intracellular calcium release. Assay and Drug Development Technologies. 9: 620-7. PMID 22087651 DOI: 10.1089/Adt.2011.0411  0.8
2011 He BJ, Joiner ML, Singh MV, Luczak ED, Swaminathan PD, Koval OM, Kutschke W, Allamargot C, Yang J, Guan X, Zimmerman K, Grumbach IM, Weiss RM, Spitz DR, Sigmund CD, ... ... Mohler PJ, et al. Oxidation of CaMKII determines the cardiotoxic effects of aldosterone. Nature Medicine. 17: 1610-8. PMID 22081025 DOI: 10.1038/Nm.2506  0.8
2011 Sturm AC, Mohler PJ. Defining the disconnect between in vitro models and human arrhythmogenic disease: context matters. Circulation. 124: 993-5. PMID 21875919 DOI: 10.1161/Circulationaha.111.051466  0.8
2011 Cunha SR, Hund TJ, Hashemi S, Voigt N, Li N, Wright P, Koval O, Li J, Gudmundsson H, Gumina RJ, Karck M, Schott JJ, Probst V, Le Marec H, Anderson ME, ... ... Mohler PJ, et al. Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation. Circulation. 124: 1212-22. PMID 21859974 DOI: 10.1161/Circulationaha.111.023986  0.8
2011 Mohler PJ, Hund TJ. Membrane-select regulation of cardiac Na(v) channel isoforms. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 8: 1931-2. PMID 21835149 DOI: 10.1016/J.Hrthm.2011.08.002  0.8
2011 Swaminathan PD, Purohit A, Soni S, Voigt N, Singh MV, Glukhov AV, Gao Z, He BJ, Luczak ED, Joiner ML, Kutschke W, Yang J, Donahue JK, Weiss RM, Grumbach IM, ... ... Mohler PJ, et al. Oxidized CaMKII causes cardiac sinus node dysfunction in mice. The Journal of Clinical Investigation. 121: 3277-88. PMID 21785215 DOI: 10.1172/Jci57833  0.8
2011 Boudoulas KD, Mohler PJ. Beyond membrane channelopathies: alternative mechanisms underlying complex human disease. Acta Pharmacologica Sinica. 32: 798-804. PMID 21642948 DOI: 10.1038/Aps.2011.34  0.8
2011 Mohler PJ, Trafford AW. The devil is in the details: methodological reviews - a new JMCC initiative. Journal of Molecular and Cellular Cardiology. 50: 939. PMID 21555005 DOI: 10.1016/J.Yjmcc.2011.04.003  0.8
2011 Curran J, Mohler PJ. Coordinating electrical activity of the heart: ankyrin polypeptides in human cardiac disease. Expert Opinion On Therapeutic Targets. 15: 789-801. PMID 21457127 DOI: 10.1517/14728222.2011.575363  0.8
2011 Gao Z, Singh MV, Hall DD, Koval OM, Luczak ED, Joiner ML, Chen B, Wu Y, Chaudhary AK, Martins JB, Hund TJ, Mohler PJ, Song LS, Anderson ME. Catecholamine-independent heart rate increases require Ca2+/calmodulin-dependent protein kinase II. Circulation. Arrhythmia and Electrophysiology. 4: 379-87. PMID 21406683 DOI: 10.1161/Circep.110.961771  0.8
2011 Li W, Li H, Sanders PN, Mohler PJ, Backs J, Olson EN, Anderson ME, Grumbach IM. The multifunctional Ca2+/calmodulin-dependent kinase II delta (CaMKIIdelta) controls neointima formation after carotid ligation and vascular smooth muscle cell proliferation through cell cycle regulation by p21. The Journal of Biological Chemistry. 286: 7990-9. PMID 21193397 DOI: 10.1074/Jbc.M110.163006  0.8
2011 Hund TJ, Mohler PJ. Differential roles for SUR subunits in KATP channel membrane targeting and regulation. American Journal of Physiology. Heart and Circulatory Physiology. 300: H33-5. PMID 21057044 DOI: 10.1152/Ajpheart.01088.2010  0.8
2011 Cunha SR, Mohler PJ. Ankyrin-based cellular pathways for cardiac ion channel and transporter targeting and regulation. Seminars in Cell & Developmental Biology. 22: 166-70. PMID 20934528 DOI: 10.1016/J.Semcdb.2010.09.013  0.8
2011 Mohler PJ, Hund TJ. Role of CaMKII in cardiovascular health, disease, and arrhythmia. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 8: 142-4. PMID 20673813 DOI: 10.1016/J.Hrthm.2010.07.029  0.8
2010 Shan J, Kushnir A, Betzenhauser MJ, Reiken S, Li J, Lehnart SE, Lindegger N, Mongillo M, Mohler PJ, Marks AR. Phosphorylation of the ryanodine receptor mediates the cardiac fight or flight response in mice. The Journal of Clinical Investigation. 120: 4388-98. PMID 21099118 DOI: 10.1172/Jci32726  0.8
2010 Hund TJ, Koval OM, Li J, Wright PJ, Qian L, Snyder JS, Gudmundsson H, Kline CF, Davidson NP, Cardona N, Rasband MN, Anderson ME, Mohler PJ. A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice. The Journal of Clinical Investigation. 120: 3508-19. PMID 20877009 DOI: 10.1172/Jci43621  0.8
2010 Yang J, Huang J, Maity B, Gao Z, Lorca RA, Gudmundsson H, Li J, Stewart A, Swaminathan PD, Ibeawuchi SR, Shepherd A, Chen CK, Kutschke W, Mohler PJ, Mohapatra DP, et al. RGS6, a modulator of parasympathetic activation in heart. Circulation Research. 107: 1345-9. PMID 20864673 DOI: 10.1161/Circresaha.110.224220  0.8
2010 Wolf RM, Mitchell CC, Christensen MD, Mohler PJ, Hund TJ. Defining new insight into atypical arrhythmia: a computational model of ankyrin-B syndrome. American Journal of Physiology. Heart and Circulatory Physiology. 299: H1505-14. PMID 20729400 DOI: 10.1152/Ajpheart.00503.2010  0.8
2010 Ackerman MJ, Mohler PJ. Defining a new paradigm for human arrhythmia syndromes: phenotypic manifestations of gene mutations in ion channel- and transporter-associated proteins. Circulation Research. 107: 457-65. PMID 20724725 DOI: 10.1161/Circresaha.110.224592  0.8
2010 Li J, Kline CF, Hund TJ, Anderson ME, Mohler PJ. Ankyrin-B regulates Kir6.2 membrane expression and function in heart. The Journal of Biological Chemistry. 285: 28723-30. PMID 20610380 DOI: 10.1074/Jbc.M110.147868  0.8
2010 Glukhov AV, Fedorov VV, Anderson ME, Mohler PJ, Efimov IR. Functional anatomy of the murine sinus node: high-resolution optical mapping of ankyrin-B heterozygous mice. American Journal of Physiology. Heart and Circulatory Physiology. 299: H482-91. PMID 20525877 DOI: 10.1152/Ajpheart.00756.2009  0.8
2010 Gudmundsson H, Hund TJ, Wright PJ, Kline CF, Snyder JS, Qian L, Koval OM, Cunha SR, George M, Rainey MA, Kashef FE, Dun W, Boyden PA, Anderson ME, Band H, ... Mohler PJ, et al. EH domain proteins regulate cardiac membrane protein targeting. Circulation Research. 107: 84-95. PMID 20489164 DOI: 10.1161/Circresaha.110.216713  0.8
2010 Gao Z, Chen B, Joiner ML, Wu Y, Guan X, Koval OM, Chaudhary AK, Cunha SR, Mohler PJ, Martins JB, Song LS, Anderson ME. I(f) and SR Ca(2+) release both contribute to pacemaker activity in canine sinoatrial node cells. Journal of Molecular and Cellular Cardiology. 49: 33-40. PMID 20380837 DOI: 10.1016/J.Yjmcc.2010.03.019  0.8
2010 Koval OM, Guan X, Wu Y, Joiner ML, Gao Z, Chen B, Grumbach IM, Luczak ED, Colbran RJ, Song LS, Hund TJ, Mohler PJ, Anderson ME. CaV1.2 beta-subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations. Proceedings of the National Academy of Sciences of the United States of America. 107: 4996-5000. PMID 20194790 DOI: 10.1073/Pnas.0913760107  0.8
2010 Leoni AL, Gavillet B, Rougier JS, Marionneau C, Probst V, Le Scouarnec S, Schott JJ, Demolombe S, Bruneval P, Huang CL, Colledge WH, Grace AA, Le Marec H, Wilde AA, Mohler PJ, et al. Variable Na(v)1.5 protein expression from the wild-type allele correlates with the penetrance of cardiac conduction disease in the Scn5a(+/-) mouse model. Plos One. 5: e9298. PMID 20174578 DOI: 10.1371/Journal.Pone.0009298  0.8
2010 Hund TJ, Mohler PJ. Cardiac spectrins: alternative splicing encodes functional diversity. Journal of Molecular and Cellular Cardiology. 48: 1031-2. PMID 20144617 DOI: 10.1016/J.Yjmcc.2010.02.002  0.8
2010 Mohler PJ. Sodium channel traffic on the cardiac microtubule highway. Cardiovascular Research. 85: 645-6. PMID 20032082 DOI: 10.1093/Cvr/Cvp404  0.8
2010 Li H, Li W, Gupta AK, Mohler PJ, Anderson ME, Grumbach IM. Calmodulin kinase II is required for angiotensin II-mediated vascular smooth muscle hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. 298: H688-98. PMID 20023119 DOI: 10.1152/Ajpheart.01014.2009  0.8
2010 Kline CF, Hund TJ, Mohler PJ. Ankyrin regulates KATP channel membrane trafficking and gating in excitable cells. Channels (Austin, Tex.). 4: 55-7. PMID 19901534 DOI: 10.4161/Chan.4.1.10362  0.8
2009 Kline CF, Mohler PJ. From Fifth Business to Protagonist: the complex roles of ion channel anchors in cardiac arrhythmia. Drug Discovery Today. Disease Models. 6: 63-69. PMID 20689672 DOI: 10.1016/J.Ddmod.2009.07.003  0.8
2009 Christensen MD, Dun W, Boyden PA, Anderson ME, Mohler PJ, Hund TJ. Oxidized calmodulin kinase II regulates conduction following myocardial infarction: a computational analysis. Plos Computational Biology. 5: e1000583. PMID 19997488 DOI: 10.1371/Journal.Pcbi.1000583  0.8
2009 Cunha SR, Mohler PJ. Ankyrin protein networks in membrane formation and stabilization Journal of Cellular and Molecular Medicine. 13: 4364-4376. PMID 19840192 DOI: 10.1111/J.1582-4934.2009.00943.X  0.8
2009 Kline CF, Kurata HT, Hund TJ, Cunha SR, Koval OM, Wright PJ, Christensen M, Anderson ME, Nichols CG, Mohler PJ. Dual role of K ATP channel C-terminal motif in membrane targeting and metabolic regulation. Proceedings of the National Academy of Sciences of the United States of America. 106: 16669-74. PMID 19805355 DOI: 10.1073/Pnas.0907138106  0.8
2009 Chen B, Wu Y, Mohler PJ, Anderson ME, Song LS. Local control of Ca2+-induced Ca2+ release in mouse sinoatrial node cells. Journal of Molecular and Cellular Cardiology. 47: 706-15. PMID 19615376 DOI: 10.1016/J.Yjmcc.2009.07.007  0.8
2009 Hashemi SM, Hund TJ, Mohler PJ. Cardiac ankyrins in health and disease. Journal of Molecular and Cellular Cardiology. 47: 203-9. PMID 19394342 DOI: 10.1016/J.Yjmcc.2009.04.010  0.8
2009 Wu Y, Gao Z, Chen B, Koval OM, Singh MV, Guan X, Hund TJ, Kutschke W, Sarma S, Grumbach IM, Wehrens XH, Mohler PJ, Song LS, Anderson ME. Calmodulin kinase II is required for fight or flight sinoatrial node physiology. Proceedings of the National Academy of Sciences of the United States of America. 106: 5972-7. PMID 19276108 DOI: 10.1073/Pnas.0806422106  0.8
2009 Singh MV, Kapoun A, Higgins L, Kutschke W, Thurman JM, Zhang R, Singh M, Yang J, Guan X, Lowe JS, Weiss RM, Zimmermann K, Yull FE, Blackwell TS, Mohler PJ, et al. Ca2+/calmodulin-dependent kinase II triggers cell membrane injury by inducing complement factor B gene expression in the mouse heart. The Journal of Clinical Investigation. 119: 986-96. PMID 19273909 DOI: 10.1172/Jci35814  0.8
2009 Tuvim MJ, Mospan AR, Burns KA, Chua M, Mohler PJ, Melicoff E, Adachi R, Ammar-Aouchiche Z, Davis CW, Dickey BF. Synaptotagmin 2 couples mucin granule exocytosis to Ca2+ signaling from endoplasmic reticulum. The Journal of Biological Chemistry. 284: 9781-7. PMID 19208631 DOI: 10.1074/Jbc.M807849200  0.8
2009 Anderson ME, Mohler PJ. Rescuing a failing heart: think globally, treat locally. Nature Medicine. 15: 25-6. PMID 19129780 DOI: 10.1038/Nm0109-25  0.8
2009 Hund TJ, Wright PJ, Dun W, Snyder JS, Boyden PA, Mohler PJ. Regulation of the ankyrin-B-based targeting pathway following myocardial infarction. Cardiovascular Research. 81: 742-9. PMID 19074823 DOI: 10.1093/Cvr/Cvn348  0.8
2008 Sedlacek K, Stark K, Cunha SR, Pfeufer A, Weber S, Berger I, Perz S, Kääb S, Wichmann HE, Mohler PJ, Hengstenberg C, Jeron A. Common genetic variants in ANK2 modulate QT interval: results from the KORA study. Circulation. Cardiovascular Genetics. 1: 93-9. PMID 20031550 DOI: 10.1161/CIRCGENETICS.108.792192  0.8
2008 Hund TJ, Mohler PJ. Ankyrin-based targeting pathway regulates human sinoatrial node automaticity. Channels (Austin, Tex.). 2: 404-6. PMID 19098452 DOI: 10.4161/Chan.2.6.7220  0.8
2008 Thiel WH, Chen B, Hund TJ, Koval OM, Purohit A, Song LS, Mohler PJ, Anderson ME. Proarrhythmic defects in Timothy syndrome require calmodulin kinase II. Circulation. 118: 2225-34. PMID 19001023 DOI: 10.1161/Circulationaha.108.788067  0.8
2008 Cunha SR, Mohler PJ. Cardiac cytoskeleton and arrhythmia: An unexpected role for protein 4.1R in cardiac excitability Circulation Research. 103: 779-781. PMID 18845816 DOI: 10.1161/Circresaha.108.186460  0.8
2008 Le Scouarnec S, Bhasin N, Vieyres C, Hund TJ, Cunha SR, Koval O, Marionneau C, Chen B, Wu Y, Demolombe S, Song LS, Le Marec H, Probst V, Schott JJ, Anderson ME, ... Mohler PJ, et al. Dysfunction in ankyrin-B-dependent ion channel and transporter targeting causes human sinus node disease. Proceedings of the National Academy of Sciences of the United States of America. 105: 15617-22. PMID 18832177 DOI: 10.1073/Pnas.0805500105  0.8
2008 Cunha SR, Le Scouarnec S, Schott JJ, Mohler PJ. Exon organization and novel alternative splicing of the human ANK2 gene: Implications for cardiac function and human cardiac disease Journal of Molecular and Cellular Cardiology. 45: 724-734. PMID 18790697 DOI: 10.1016/J.Yjmcc.2008.08.005  0.8
2008 Cunha SR, Mohler PJ. Obscurin targets ankyrin-B and protein phosphatase 2A to the cardiac M-line Journal of Biological Chemistry. 283: 31968-31980. PMID 18782775 DOI: 10.1074/Jbc.M806050200  0.8
2008 Hund TJ, Decker KF, Kanter E, Mohler PJ, Boyden PA, Schuessler RB, Yamada KA, Rudy Y. Role of activated CaMKII in abnormal calcium homeostasis and I(Na) remodeling after myocardial infarction: insights from mathematical modeling. Journal of Molecular and Cellular Cardiology. 45: 420-8. PMID 18639555 DOI: 10.1016/J.Yjmcc.2008.06.007  0.8
2008 Hund TJ, Ziman AP, Lederer WJ, Mohler PJ. The cardiac IP3 receptor: uncovering the role of "the other" calcium-release channel. Journal of Molecular and Cellular Cardiology. 45: 159-61. PMID 18598702 DOI: 10.1016/J.Yjmcc.2008.06.001  0.8
2008 Erickson JR, Joiner ML, Guan X, Kutschke W, Yang J, Oddis CV, Bartlett RK, Lowe JS, O'Donnell SE, Aykin-Burns N, Zimmerman MC, Zimmerman K, Ham AJ, Weiss RM, Spitz DR, ... ... Mohler PJ, et al. A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation. Cell. 133: 462-74. PMID 18455987 DOI: 10.1016/J.Cell.2008.02.048  0.8
2008 Mohler PJ, Anderson ME. New insights into genetic causes of sinus node disease and atrial fibrillation. Journal of Cardiovascular Electrophysiology. 19: 516-8. PMID 18298510 DOI: 10.1111/J.1540-8167.2007.01097.X  0.8
2008 Kline CF, Cunha SR, Lowe JS, Hund TJ, Mohler PJ. Revisiting ankyrin-InsP3 receptor interactions: ankyrin-B associates with the cytoplasmic N-terminus of the InsP3 receptor. Journal of Cellular Biochemistry. 104: 1244-53. PMID 18275062 DOI: 10.1002/Jcb.21704  0.8
2008 Lowe JS, Palygin O, Bhasin N, Hund TJ, Boyden PA, Shibata E, Anderson ME, Mohler PJ. Voltage-gated Nav channel targeting in the heart requires an ankyrin-G dependent cellular pathway. The Journal of Cell Biology. 180: 173-86. PMID 18180363 DOI: 10.1083/Jcb.200710107  0.8
2007 Li J, Marionneau C, Koval O, Zingman L, Mohler PJ, Nerbonne JM, Anderson ME. Calmodulin kinase II inhibition enhances ischemic preconditioning by augmenting ATP-sensitive K+ current. Channels (Austin, Tex.). 1: 387-94. PMID 18690039 DOI: 10.4161/Chan.5449  0.8
2007 Lehnart SE, Ackerman MJ, Benson DW, Brugada R, Clancy CE, Donahue JK, George AL, Grant AO, Groft SC, January CT, Lathrop DA, Lederer WJ, Makielski JC, Mohler PJ, Moss A, et al. Inherited arrhythmias: a National Heart, Lung, and Blood Institute and Office of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutations affecting ion channel function. Circulation. 116: 2325-45. PMID 17998470 DOI: 10.1161/Circulationaha.107.711689  0.8
2007 Mohler PJ, Healy JA, Xue H, Puca AA, Kline CF, Allingham RR, Kranias EG, Rockman HA, Bennett V. Ankyrin-B syndrome: enhanced cardiac function balanced by risk of cardiac death and premature senescence. Plos One. 2: e1051. PMID 17940615 DOI: 10.1371/Journal.Pone.0001051  0.8
2007 Mohler PJ, Wehrens XHT. Mechanisms of human arrhythmia syndromes: Abnormal cardiac macromolecular interactions Physiology. 22: 342-350. PMID 17928548 DOI: 10.1152/Physiol.00018.2007  0.8
2007 Mohler PJ, Zhu MY, Blade AM, Ham AJL, Shelness GS, Swift LL. Identification of a novel isoform of microsomal triglyceride transfer protein Journal of Biological Chemistry. 282: 26981-26988. PMID 17635917 DOI: 10.1074/Jbc.M700500200  0.8
2007 Bhasin N, Cunha SR, Mudannayake M, Gigena MS, Rogers TB, Mohler PJ. Molecular basis for PP2A regulatory subunit B56alpha targeting in cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology. 293: H109-19. PMID 17416611 DOI: 10.1152/Ajpheart.00059.2007  0.8
2007 Anderson ME, Mohler PJ. MicroRNA may have macro effect on sudden death. Nature Medicine. 13: 410-1. PMID 17415373 DOI: 10.1038/Nm0407-410  0.8
2007 Mohler PJ, Le Scouarnec S, Denjoy I, Lowe JS, Guicheney P, Caron L, Driskell IM, Schott JJ, Norris K, Leenhardt A, Kim RB, Escande D, Roden DM. Defining the cellular phenotype of "ankyrin-B syndrome" variants: human ANK2 variants associated with clinical phenotypes display a spectrum of activities in cardiomyocytes. Circulation. 115: 432-41. PMID 17242276 DOI: 10.1161/Circulationaha.106.656512  0.8
2007 Cunha SR, Bhasin N, Mohler PJ. Targeting and stability of Na/Ca exchanger 1 in cardiomyocytes requires direct interaction with the membrane adaptor ankyrin-B. The Journal of Biological Chemistry. 282: 4875-83. PMID 17178715 DOI: 10.1074/Jbc.M607096200  0.8
2007 Kizhatil K, Yoon W, Mohler PJ, Davis LH, Hoffman JA, Bennett V. Ankyrin-G and beta2-spectrin collaborate in biogenesis of lateral membrane of human bronchial epithelial cells. The Journal of Biological Chemistry. 282: 2029-37. PMID 17074766 DOI: 10.1074/Jbc.M608921200  0.8
2006 Grueter CE, Abiria SA, Dzhura I, Wu Y, Ham AJ, Mohler PJ, Anderson ME, Colbran RJ. L-type Ca2+ channel facilitation mediated by phosphorylation of the beta subunit by CaMKII. Molecular Cell. 23: 641-50. PMID 16949361 DOI: 10.1016/J.Molcel.2006.07.006  0.8
2006 Kline CF, Mohler PJ. Weighing in on molecular anchors: The role of ankyrin polypeptides in human arrhythmia Expert Review of Cardiovascular Therapy. 4: 477-485. PMID 16918266 DOI: 10.1586/14779072.4.4.477  0.8
2006 Mohler PJ. Ankyrins and human disease: What the electrophysiologist should know Journal of Cardiovascular Electrophysiology. 17: 1153-1159. PMID 16800854 DOI: 10.1111/J.1540-8167.2006.00540.X  0.8
2006 Cunha SR, Mohler PJ. Cardiac ankyrins: Essential components for development and maintenance of excitable membrane domains in heart Cardiovascular Research. 71: 22-29. PMID 16650839 DOI: 10.1016/j.cardiores.2006.03.018  0.8
2006 Hodson CA, Ambrogi IG, Scott RO, Mohler PJ, Milgram SL. Polarized apical sorting of guanylyl cyclase C is specified by a cytosolic signal. Traffic (Copenhagen, Denmark). 7: 456-64. PMID 16536743 DOI: 10.1111/J.1600-0854.2006.00398.X  0.8
2006 Braun NA, Mohler PJ, Weisgraber KH, Hasty AH, Linton MF, Yancey PG, Su YR, Fazio S, Swift LL. Intracellular trafficking of recycling apolipoprotein E in Chinese hamster ovary cells. Journal of Lipid Research. 47: 1176-86. PMID 16534141 DOI: 10.1194/Jlr.M500503-Jlr200  0.8
2006 Abdi KM, Mohler PJ, Davis JQ, Bennett V. Isoform specificity of ankyrin-B: a site in the divergent C-terminal domain is required for intramolecular association. The Journal of Biological Chemistry. 281: 5741-9. PMID 16368689 DOI: 10.1074/Jbc.M506697200  0.8
2005 Mohler PJ, Davis JQ, Bennett V. Ankyrin-B coordinates the Na/K ATPase, Na/Ca exchanger, and InsP3 receptor in a cardiac T-tubule/SR microdomain. Plos Biology. 3: e423. PMID 16292983 DOI: 10.1371/Journal.Pbio.0030423  0.8
2005 Mohler PJ, Bennett V. Defects in ankyrin-based cellular pathways in metazoan physiology. Frontiers in Bioscience : a Journal and Virtual Library. 10: 2832-40. PMID 15970537  0.8
2005 Swift LL, Kakkad B, Boone C, Jovanovska A, Jerome WG, Mohler PJ, Ong DE. Microsomal triglyceride transfer protein expression in adipocytes: a new component in fat metabolism. Febs Letters. 579: 3183-9. PMID 15922333 DOI: 10.1016/J.Febslet.2005.05.009  0.8
2005 Mohler PJ, Bennett V. Ankyrin-based cardiac arrhythmias: a new class of channelopathies due to loss of cellular targeting. Current Opinion in Cardiology. 20: 189-93. PMID 15861006 DOI: 10.1097/01.Hco.0000160372.95116.3E  0.8
2004 Mohler PJ, Rivolta I, Napolitano C, LeMaillet G, Lambert S, Priori SG, Bennett V. Nav1.5 E1053K mutation causing Brugada syndrome blocks binding to ankyrin-G and expression of Nav1.5 on the surface of cardiomyocytes. Proceedings of the National Academy of Sciences of the United States of America. 101: 17533-8. PMID 15579534 DOI: 10.1073/Pnas.0403711101  0.8
2004 Mohler PJ, Yoon W, Bennett V. Ankyrin-B targets beta2-spectrin to an intracellular compartment in neonatal cardiomyocytes. The Journal of Biological Chemistry. 279: 40185-93. PMID 15262991 DOI: 10.1074/Jbc.M406018200  0.8
2004 Mohler PJ, Splawski I, Napolitano C, Bottelli G, Sharpe L, Timothy K, Priori SG, Keating MT, Bennett V. A cardiac arrhythmia syndrome caused by loss of ankyrin-B function. Proceedings of the National Academy of Sciences of the United States of America. 101: 9137-42. PMID 15178757 DOI: 10.1073/Pnas.0402546101  0.8
2004 Mohler PJ, Hoffman JA, Davis JQ, Abdi KM, Kim CR, Jones SK, Davis LH, Roberts KF, Bennett V. Isoform specificity among ankyrins. An amphipathic alpha-helix in the divergent regulatory domain of ankyrin-b interacts with the molecular co-chaperone Hdj1/Hsp40. The Journal of Biological Chemistry. 279: 25798-804. PMID 15075330 DOI: 10.1074/Jbc.M401296200  0.8
2004 Mohler PJ, Davis JQ, Davis LH, Hoffman JA, Michaely P, Bennett V. Inositol 1,4,5-trisphosphate receptor localization and stability in neonatal cardiomyocytes requires interaction with ankyrin-B. The Journal of Biological Chemistry. 279: 12980-7. PMID 14722080 DOI: 10.1074/Jbc.M313979200  0.8
2004 Facemire CS, Mohler PJ, Arendshorst WJ. Expression and relative abundance of short transient receptor potential channels in the rat renal microcirculation American Journal of Physiology - Renal Physiology. 286: F546-F551. PMID 14678949 DOI: 10.1152/Ajprenal.00338.2003  0.8
2003 Wehrens XH, Lehnart SE, Huang F, Vest JA, Reiken SR, Mohler PJ, Sun J, Guatimosim S, Song LS, Rosemblit N, D'Armiento JM, Napolitano C, Memmi M, Priori SG, Lederer WJ, et al. FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death. Cell. 113: 829-40. PMID 12837242 DOI: 10.1016/S0092-8674(03)00434-3  0.8
2003 Mohler PJ, Schott JJ, Gramolini AO, Dilly KW, Guatimosim S, duBell WH, Song LS, Haurogné K, Kyndt F, Ali ME, Rogers TB, Lederer WJ, Escande D, Le Marec H, Bennett V. Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death. Nature. 421: 634-9. PMID 12571597 DOI: 10.1038/Nature01335  0.8
2002 Mohler PJ, Gramolini AO, Bennett V. Ankyrins. Journal of Cell Science. 115: 1565-6. PMID 11950874  0.8
2002 Mohler PJ, Kultgen PL, Stutts MJ, Milgram SL. Biochemical assays for studying indirect interactions between CFTR and the cytoskeleton. Methods in Molecular Medicine. 70: 383-94. PMID 11917538 DOI: 10.1385/1-59259-187-6:383  0.8
2002 Mohler PJ, Gramolini AO, Bennett V. The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytes. The Journal of Biological Chemistry. 277: 10599-607. PMID 11781319 DOI: 10.1074/Jbc.M110958200  0.8
2001 Goy MF, Oliver PM, Purdy KE, Knowles JW, Fox JE, Mohler PJ, Qian X, Smithies O, Maeda N. Evidence for a novel natriuretic peptide receptor that prefers brain natriuretic peptide over atrial natriuretic peptide. The Biochemical Journal. 358: 379-87. PMID 11513736 DOI: 10.1042/0264-6021:3580379  0.8
1999 Mohler PJ, Kreda SM, Boucher RC, Sudol M, Stutts MJ, Milgram SL. Yes-associated protein 65 localizes p62(c-Yes) to the apical compartment of airway epithelia by association with EBP50. The Journal of Cell Biology. 147: 879-90. PMID 10562288 DOI: 10.1083/Jcb.147.4.879  0.8
1996 Browne CL, Creton R, Karplus E, Mohler PJ, Palazzo RE, Miller AL. Analysis of the calcium transient at NEB during the first cell cycle in dividing sea urchin eggs Biological Bulletin. 191: 5-16. PMID 8776840 DOI: 10.2307/1543056  0.8
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