Michy P. Kelly - Publications

Pharmacology, Physiology & Neuroscience University of South Carolina School of Medicine, Columbia, SC, United States 
schizophrenia, sensorimotor gating, learning & memory, cyclic nucleotides, phosphodiesterases, drug development

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Pilarzyk K, Porcher L, Capell WR, Burbano SD, Davis J, Fisher JL, Gorny N, Petrolle S, Kelly MP. Conserved age-related increases in hippocampal PDE11A4 cause unexpected proteinopathies and cognitive decline of social associative memories. Aging Cell. e13687. PMID 36073342 DOI: 10.1111/acel.13687  0.309
2021 Smith AJ, Farmer R, Pilarzyk K, Porcher L, Kelly MP. A genetic basis for friendship? Homophily for membrane-associated PDE11A-cAMP-CREB signaling in CA1 of hippocampus dictates mutual social preference in male and female mice. Molecular Psychiatry. PMID 34321593 DOI: 10.1038/s41380-021-01237-4  0.34
2020 Kelly MP, Heckman PRA, Havekes R. Genetic manipulation of cyclic nucleotide signaling during hippocampal neuroplasticity and memory formation. Progress in Neurobiology. 101799. PMID 32360536 DOI: 10.1016/J.Pneurobio.2020.101799  0.638
2020 Farmer R, Burbano SD, Patel NS, Sarmiento A, Smith AJ, Kelly MP. Phosphodiesterases PDE2A and PDE10A both change mRNA expression in the human brain with age, but only PDE2A changes in a region-specific manner with psychiatric disease. Cellular Signalling. 109592. PMID 32119913 DOI: 10.1016/J.Cellsig.2020.109592  0.335
2019 Pilarzyk K, Klett J, Pena EA, Porcher L, Smith AJ, Kelly MP. Loss of Function of Phosphodiesterase 11A4 Shows that Recent and Remote Long-Term Memories Can Be Uncoupled. Current Biology : Cb. PMID 31303492 DOI: 10.1016/J.Cub.2019.06.018  0.454
2018 Patel NS, Klett J, Pilarzyk K, Lee DI, Kass D, Menniti FS, Kelly MP. Identification of new PDE9A isoforms and how their expression and subcellular compartmentalization in the brain change across the life span. Neurobiology of Aging. 65: 217-234. PMID 29505961 DOI: 10.1016/J.Neurobiolaging.2018.01.019  0.342
2018 Kelly MP. Cyclic nucleotide signaling changes associated with normal aging and age-related diseases of the brain. Cellular Signalling. 42: 281-291. PMID 29175000 DOI: 10.1016/J.Cellsig.2017.11.004  0.332
2017 Kelly MP. A Role for Phosphodiesterase 11A (PDE11A) in the Formation of Social Memories and the Stabilization of Mood. Advances in Neurobiology. 17: 201-230. PMID 28956334 DOI: 10.1007/978-3-319-58811-7_8  0.415
2016 Pathak G, Agostino MJ, Bishara K, Capell WR, Fisher JL, Hegde S, Ibrahim BA, Pilarzyk K, Sabin C, Tuczkewycz T, Wilson S, Kelly MP. PDE11A negatively regulates lithium responsivity. Molecular Psychiatry. PMID 27646265 DOI: 10.1038/Mp.2016.155  0.623
2016 Hegde S, Ji H, Oliver D, Patel NS, Poupore N, Shtutman M, Kelly MP. PDE11A regulates social behaviors and is a key mechanism by which social experience sculpts the brain. Neuroscience. PMID 27544407 DOI: 10.1016/J.Neuroscience.2016.08.019  0.56
2016 Hegde S, Capell WR, Ibrahim BA, Klett J, Patel NS, Sougiannis AT, Kelly MP. Phosphodiesterase 11A (PDE11A), Enriched in Ventral Hippocampus Neurons, is Required for Consolidation of Social but not Non-Social Memories in Mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27339393 DOI: 10.1038/Npp.2016.106  0.677
2015 Pathak G, Ibrahim BA, McCarthy SA, Baker K, Kelly MP. Amphetamine sensitization in mice is sufficient to produce both manic- and depressive-related behaviors as well as changes in the functional connectivity of corticolimbic structures. Neuropharmacology. 95: 434-47. PMID 25959066 DOI: 10.1016/J.Neuropharm.2015.04.026  0.626
2015 Kelly MP. Does phosphodiesterase 11A (PDE11A) hold promise as a future therapeutic target? Current Pharmaceutical Design. 21: 389-416. PMID 25159071 DOI: 10.2174/1381612820666140826114941  0.325
2014 Kelly MP, Adamowicz W, Bove S, Hartman AJ, Mariga A, Pathak G, Reinhart V, Romegialli A, Kleiman RJ. Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain. Cellular Signalling. 26: 383-97. PMID 24184653 DOI: 10.1016/J.Cellsig.2013.10.007  0.349
2011 Kelly MP, Brandon NJ. Taking a bird's eye view on a mouse model review: A comparison of findings from mouse models targeting DISC1 or DISC1-interacting proteins Future Neurology. 6: 661-677. DOI: 10.2217/Fnl.11.39  0.354
2010 Kelly MP, Logue SF, Brennan J, Day JP, Lakkaraju S, Jiang L, Zhong X, Tam M, Sukoff Rizzo SJ, Platt BJ, Dwyer JM, Neal S, Pulito VL, Agostino MJ, Grauer SM, et al. Phosphodiesterase 11A in brain is enriched in ventral hippocampus and deletion causes psychiatric disease-related phenotypes. Proceedings of the National Academy of Sciences of the United States of America. 107: 8457-62. PMID 20404172 DOI: 10.1073/Pnas.1000730107  0.464
2009 Kelly MP, Brandon NJ. Differential function of phosphodiesterase families in the brain: gaining insights through the use of genetically modified animals. Progress in Brain Research. 179: 67-73. PMID 20302819 DOI: 10.1016/S0079-6123(09)17908-6  0.33
2009 Grauer SM, Pulito VL, Navarra RL, Kelly MP, Kelley C, Graf R, Langen B, Logue S, Brennan J, Jiang L, Charych E, Egerland U, Liu F, Marquis KL, Malamas M, et al. Phosphodiesterase 10A inhibitor activity in preclinical models of the positive, cognitive, and negative symptoms of schizophrenia. The Journal of Pharmacology and Experimental Therapeutics. 331: 574-90. PMID 19661377 DOI: 10.1124/Jpet.109.155994  0.436
2009 Kelly MP, Logue SF, Dwyer JM, Beyer CE, Majchrowski H, Cai Z, Liu Z, Adedoyin A, Rosenzweig-Lipson S, Comery TA. The supra-additive hyperactivity caused by an amphetamine-chlordiazepoxide mixture exhibits an inverted-U dose response: negative implications for the use of a model in screening for mood stabilizers. Pharmacology, Biochemistry, and Behavior. 92: 649-54. PMID 19303035 DOI: 10.1016/J.Pbb.2009.03.003  0.304
2009 Kelly MP, Stein JM, Vecsey CG, Favilla C, Yang X, Bizily SF, Esposito MF, Wand G, Kanes SJ, Abel T. Developmental etiology for neuroanatomical and cognitive deficits in mice overexpressing Galphas, a G-protein subunit genetically linked to schizophrenia. Molecular Psychiatry. 14: 398-415, 347. PMID 19030002 DOI: 10.1038/Mp.2008.124  0.746
2009 Kelly MP, Stein JM, Abel T. Developmental or adulthood overexpression of Gαs, a G-protein subunit genetically linked to schizophrenia, is sufficient to cause enlarged lateral ventricles and a smaller dorsal and ventral striatum in adult mice Molecular Psychiatry. 14: 347. DOI: 10.1038/Mp.2009.23  0.682
2009 Kelly MP, Stein JM, Vecsey CG, Favilla C, Yang X, Bizily SF, Esposito MF, Wand G, Kanes SJ, Abel T. Erratum: Developmental etiology for neuroanatomical and cognitive deficits in mice overexpressing Gαs, a G-protein subunit genetically linked to schizophrenia Molecular Psychiatry. 14: 1145-1145. DOI: 10.1038/Mp.2008.138  0.727
2008 Favilla C, Abel T, Kelly MP. Chronic Galphas signaling in the striatum increases anxiety-related behaviors independent of developmental effects. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13952-6. PMID 19091983 DOI: 10.1523/Jneurosci.4986-08.2008  0.551
2008 Kelly MP, Cheung YF, Favilla C, Siegel SJ, Kanes SJ, Houslay MD, Abel T. Constitutive activation of the G-protein subunit Galphas within forebrain neurons causes PKA-dependent alterations in fear conditioning and cortical Arc mRNA expression. Learning & Memory (Cold Spring Harbor, N.Y.). 15: 75-83. PMID 18230676 DOI: 10.1101/Lm.723708  0.61
2007 Kanes SJ, Tokarczyk J, Siegel SJ, Bilker W, Abel T, Kelly MP. Rolipram: a specific phosphodiesterase 4 inhibitor with potential antipsychotic activity. Neuroscience. 144: 239-46. PMID 17081698 DOI: 10.1016/J.Neuroscience.2006.09.026  0.536
2007 Kelly MP, Isiegas C, Cheung YF, Tokarczyk J, Yang X, Esposito MF, Rapoport DA, Fabian SA, Siegel SJ, Wand G, Houslay MD, Kanes SJ, Abel T. Constitutive activation of Galphas within forebrain neurons causes deficits in sensorimotor gating because of PKA-dependent decreases in cAMP. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 577-88. PMID 16738544 DOI: 10.1038/Sj.Npp.1301099  0.617
2006 Bourtchouladze R, Patterson SL, Kelly MP, Kreibich A, Kandel ER, Abel T. Chronically increased Gsalpha signaling disrupts associative and spatial learning. Learning & Memory (Cold Spring Harbor, N.Y.). 13: 745-52. PMID 17142304 DOI: 10.1101/Lm.354106  0.643
2006 Maxwell CR, Liang Y, Kelly MP, Kanes SJ, Abel T, Siegel SJ. Mice expressing constitutively active Gsalpha exhibit stimulus encoding deficits similar to those observed in schizophrenia patients. Neuroscience. 141: 1257-64. PMID 16750890 DOI: 10.1016/J.Neuroscience.2006.04.028  0.611
2004 Gould TJ, Bizily SP, Tokarczyk J, Kelly MP, Siegel SJ, Kanes SJ, Abel T. Sensorimotor gating deficits in transgenic mice expressing a constitutively active form of Gs alpha. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 494-501. PMID 14694347 DOI: 10.1038/Sj.Npp.1300309  0.623
2003 Kelly MP, Deadwyler SA. Experience-dependent regulation of the immediate-early gene arc differs across brain regions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 6443-51. PMID 12878684 DOI: 10.1523/Jneurosci.23-16-06443.2003  0.543
2002 Kelly MP, Deadwyler SA. Acquisition of a novel behavior induces higher levels of Arc mRNA than does overtrained performance. Neuroscience. 110: 617-26. PMID 11934470 DOI: 10.1016/S0306-4522(01)00605-4  0.541
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