Edward B. Brown, Ph.D. - Publications

Affiliations: 
Biomedical Engineering University of Rochester, Rochester, NY 
Website:
http://www.urmc.rochester.edu/labs/Brown-Lab/

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Pan XS, Li J, Brown EB, Kuo CK. Embryo movements regulate tendon mechanical property development. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373. PMID 30249775 DOI: 10.1098/rstb.2017.0325  0.4
2016 Ramirez G, Proctor AR, Jung KW, Wu TT, Han S, Adams RR, Ren J, Byun DK, Madden KS, Brown EB, Foster TH, Farzam P, Durduran T, Choe R. Chemotherapeutic drug-specific alteration of microvascular blood flow in murine breast cancer as measured by diffuse correlation spectroscopy. Biomedical Optics Express. 7: 3610-3630. PMID 27699124 DOI: 10.1364/BOE.7.003610  0.68
2015 Burke K, Smid M, Dawes RP, Timmermans MA, Salzman P, van Deurzen CH, Beer DG, Foekens JA, Brown E. Using second harmonic generation to predict patient outcome in solid tumors. Bmc Cancer. 15: 929. PMID 26603532 DOI: 10.1186/s12885-015-1911-8  0.96
2015 Van Hove AH, Burke K, Antonienko E, Brown E, Benoit DS. Enzymatically-responsive pro-angiogenic peptide-releasing poly(ethylene glycol) hydrogels promote vascularization in vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society. 217: 191-201. PMID 26365781 DOI: 10.1016/j.jconrel.2015.09.005  0.96
2015 Kottmann RM, Sharp J, Owens K, Salzman P, Xiao GQ, Phipps RP, Sime PJ, Brown EB, Perry SW. Second harmonic generation microscopy reveals altered collagen microstructure in usual interstitial pneumonia versus healthy lung. Respiratory Research. 16: 61. PMID 26013144 DOI: 10.1186/s12931-015-0220-8  0.96
2015 Huang C, Ness VP, Yang X, Chen H, Luo J, Brown EB, Zhang X. Spatiotemporal Analyses of Osteogenesis and Angiogenesis via Intravital Imaging in Cranial Bone Defect Repair. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 1217-30. PMID 25640220 DOI: 10.1002/jbmr.2460  0.96
2015 Haynes-Gimore N, Banach M, Brown E, Dawes R, Edholm ES, Kim M, Robert J. Semi-solid tumor model in Xenopus laevis/gilli cloned tadpoles for intravital study of neovascularization, immune cells and melanophore infiltration. Developmental Biology. PMID 25601449 DOI: 10.1016/j.ydbio.2015.01.003  0.96
2015 Bouta EM, Li J, Ju Y, Brown EB, Ritchlin CT, Xing L, Schwarz EM. The role of the lymphatic system in inflammatory-erosive arthritis. Seminars in Cell & Developmental Biology. 38: 90-7. PMID 25598390 DOI: 10.1016/j.semcdb.2015.01.001  0.96
2015 Sullivan KD, Majewska AK, Brown EB. Single- and two-photon fluorescence recovery after photobleaching. Cold Spring Harbor Protocols. 2015: pdb.top083519. PMID 25561627 DOI: 10.1101/pdb.top083519  0.96
2015 Van Hove AH, Antonienko E, Burke K, Brown E, Benoit DSW. Temporally Tunable, Enzymatically Responsive Delivery of Proangiogenic Peptides from Poly(ethylene glycol) Hydrogels Advanced Healthcare Materials. DOI: 10.1002/adhm.201500304  0.96
2014 Shapovalov Y, Zettel M, Spielman SC, Amico-Ruvio SA, Kelly EA, Sipe GO, Dickerson IM, Majewska AK, Brown EB. Fluoxetine modulates breast cancer metastasis to the brain in a murine model. Bmc Cancer. 14: 598. PMID 25129445 DOI: 10.1186/1471-2407-14-598  0.96
2014 Bouta EM, Wood RW, Brown EB, Rahimi H, Ritchlin CT, Schwarz EM. In vivo quantification of lymph viscosity and pressure in lymphatic vessels and draining lymph nodes of arthritic joints in mice. The Journal of Physiology. 592: 1213-23. PMID 24421350 DOI: 10.1113/jphysiol.2013.266700  0.96
2014 Burke KA, Dawes RP, Cheema MK, Perry S, Brown E. Second-harmonic generation reveals a relationship between metastatic potential and collagen fiber structure Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8948. DOI: 10.1117/12.2041027  0.96
2013 Szpunar MJ, Burke KA, Dawes RP, Brown EB, Madden KS. The antidepressant desipramine and α2-adrenergic receptor activation promote breast tumor progression in association with altered collagen structure. Cancer Prevention Research (Philadelphia, Pa.). 6: 1262-72. PMID 24309563 DOI: 10.1158/1940-6207.CAPR-13-0079  0.96
2013 Perry SW, Schueckler JM, Burke K, Arcuri GL, Brown EB. Stromal matrix metalloprotease-13 knockout alters Collagen I structure at the tumor-host interface and increases lung metastasis of C57BL/6 syngeneic E0771 mammary tumor cells. Bmc Cancer. 13: 411. PMID 24010522 DOI: 10.1186/1471-2407-13-411  0.96
2013 Burke RM, Madden KS, Perry SW, Zettel ML, Brown EB. Tumor-associated macrophages and stromal TNF-α regulate collagen structure in a breast tumor model as visualized by second harmonic generation. Journal of Biomedical Optics. 18: 86003. PMID 23912760 DOI: 10.1117/1.JBO.18.8.086003  0.96
2013 Arendt O, Schwaller B, Brown EB, Eilers J, Schmidt H. Restricted diffusion of calretinin in cerebellar granule cell dendrites implies Ca²⁺-dependent interactions via its EF-hand 5 domain. The Journal of Physiology. 591: 3887-99. PMID 23732647 DOI: 10.1113/jphysiol.2013.256628  0.96
2013 Madden KS, Zettel ML, Majewska AK, Brown EB. Brain tumor imaging: imaging brain metastasis using a brain-metastasizing breast adenocarcinoma. Cold Spring Harbor Protocols. 2013. PMID 23457349 DOI: 10.1101/pdb.prot073676  0.96
2013 Madden KS, Zettel ML, Majewska AK, Brown EB. Brain tumor imaging: live imaging of glioma by two-photon microscopy. Cold Spring Harbor Protocols. 2013. PMID 23457348 DOI: 10.1101/pdb.prot073668  0.96
2013 Chen T, Hilton MJ, Brown EB, Zuscik MJ, Awad HA. Engineering superficial zone features in tissue engineered cartilage. Biotechnology and Bioengineering. 110: 1476-86. PMID 23239161 DOI: 10.1002/bit.24799  0.96
2013 Burke K, Tang P, Brown E. Second harmonic generation reveals matrix alterations during breast tumor progression. Journal of Biomedical Optics. 18: 31106. PMID 23172133 DOI: 10.1117/1.JBO.18.3.031106  0.96
2013 Madden KS, Szpunar MJ, Brown EB. Early impact of social isolation and breast tumor progression in mice. Brain, Behavior, and Immunity. 30: S135-41. PMID 22610067 DOI: 10.1016/j.bbi.2012.05.003  0.96
2012 Perry SW, Burke RM, Brown EB. Two-photon and second harmonic microscopy in clinical and translational cancer research. Annals of Biomedical Engineering. 40: 277-91. PMID 22258888 DOI: 10.1007/s10439-012-0512-9  0.96
2011 Bouta EM, Wood RW, Perry SW, Brown EB, Ritchlin CT, Xing L, Schwarz EM. Measuring intranodal pressure and lymph viscosity to elucidate mechanisms of arthritic flare and therapeutic outcomes. Annals of the New York Academy of Sciences. 1240: 47-52. PMID 22172039 DOI: 10.1111/j.1749-6632.2011.06237.x  0.96
2011 Sullivan KD, Brown EB. Multiphoton fluorescence recovery after photobleaching in bounded systems. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 83: 051916. PMID 21728580 DOI: 10.1103/PhysRevE.83.051916  0.96
2011 Perry SW, Norman JP, Barbieri J, Brown EB, Gelbard HA. Mitochondrial membrane potential probes and the proton gradient: a practical usage guide. Biotechniques. 50: 98-115. PMID 21486251 DOI: 10.2144/000113610  0.96
2011 Madden KS, Szpunar MJ, Brown EB. β-Adrenergic receptors (β-AR) regulate VEGF and IL-6 production by divergent pathways in high β-AR-expressing breast cancer cell lines. Breast Cancer Research and Treatment. 130: 747-58. PMID 21234673 DOI: 10.1007/s10549-011-1348-y  0.96
2011 Nagarajan MB, Han X, Huber MB, Foster TH, Brown EB, Wismüller A. Quantitative analysis of tumor matrix patterns through statistical and topological texture features Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7965. DOI: 10.1117/12.878619  0.96
2011 Han X, Lapeira J, Burke R, Perry S, Madden K, Brown EB. In vivo imaging of tumors using multiphoton fluorescence and second harmonic generation Optics Infobase Conference Papers. DOI: 10.1101/pdb.prot5452  0.96
2010 Kozai TD, Marzullo TC, Hooi F, Langhals NB, Majewska AK, Brown EB, Kipke DR. Reduction of neurovascular damage resulting from microelectrode insertion into the cerebral cortex using in vivo two-photon mapping. Journal of Neural Engineering. 7: 046011. PMID 20644246 DOI: 10.1088/1741-2560/7/4/046011  0.96
2010 Han X, Brown E. Measurement of the ratio of forward-propagating to back-propagating second harmonic signal using a single objective. Optics Express. 18: 10538-50. PMID 20588906 DOI: 10.1364/OE.18.010538  0.96
2010 Sullivan KD, Brown EB. Measuring diffusion coefficients via two-photon fluorescence recovery after photobleaching. Journal of Visualized Experiments : Jove. PMID 20190730 DOI: 10.3791/1636  0.96
2010 Li J, Sullivan KD, Brown EB, Anthamatten M. Thermally activated diffusion in reversibly associating polymers Soft Matter. 6: 235-238. DOI: 10.1039/b909662k  0.96
2010 Han X, Brown E. Epi-detected ratio of forward-propagating to back-propagating second harmonic signal Optics Infobase Conference Papers 0.96
2009 Chauhan VP, Lanning RM, Diop-Frimpong B, Mok W, Brown EB, Padera TP, Boucher Y, Jain RK. Multiscale measurements distinguish cellular and interstitial hindrances to diffusion in vivo. Biophysical Journal. 97: 330-6. PMID 19580771 DOI: 10.1016/j.bpj.2009.03.064  0.96
2009 Sullivan KD, Sipprell WH, Brown EB, Brown EB. Improved model of fluorescence recovery expands the application of multiphoton fluorescence recovery after photobleaching in vivo. Biophysical Journal. 96: 5082-94. PMID 19527668 DOI: 10.1016/j.bpj.2009.04.020  0.56
2008 Han X, Burke RM, Zettel ML, Tang P, Brown EB. Second harmonic properties of tumor collagen: determining the structural relationship between reactive stroma and healthy stroma. Optics Express. 16: 1846-59. PMID 18542263 DOI: 10.1364/OE.16.001846  0.96
2008 Han X, Burke RM, Brown EB. Assessment of second harmonic properties of tumor collagen: Determining the structural relationship between reactive stroma and healthy stroma Biomedical Optics, Biomed 2008. BTuF60.  0.96
2008 Han X, Burke RM, Brown EB. Assessment of second harmonic properties of tumor collagen: Determining the structural relationship between reactive stroma and healthy stroma Biomedical Optics, Biomed 2008. BTuF60.  0.96
2008 Han X, Burke RM, Brown EB. Assessment of second harmonic properties of tumor collagen: Determining the structural relationship between reactive stroma and healthy stroma Biomedical Optics, Biomed 2008. BTuF60.  0.96
2007 Schmidt H, Arendt O, Brown EB, Schwaller B, Eilers J. Parvalbumin is freely mobile in axons, somata and nuclei of cerebellar Purkinje neurones. Journal of Neurochemistry. 100: 727-35. PMID 17263794 DOI: 10.1111/j.1471-4159.2006.04231.x  0.96
2007 Jain RK, Fukumura D, Munn L, Brown E. Optical Microscopy in Small Animal Research Textbook of in Vivo Imaging in Vertebrates. 183-190. DOI: 10.1002/9780470029596.ch6  0.96
2007 Ntziachristos V, Cuénod CA, Fournier L, Balvay D, Pradel C, Siauve N, Clement O, Jouannot E, Lucidarme O, Vecchio SD, Salvatore M, Law B, Tung CH, Jain RK, Fukumura D, ... ... Brown EB, et al. Tumor Imaging Textbook of in Vivo Imaging in Vertebrates. 277-309. DOI: 10.1002/9780470029596.ch11  0.96
2006 Tyrrell JA, Roysam B, Di Tomaso E, Tong R, Brown EB, Jain RK. Robust 3-D modeling of tumor microvasculature using superellipsoids 2006 3rd Ieee International Symposium On Biomedical Imaging: From Nano to Macro - Proceedings. 2006: 185-188.  0.96
2006 Brown E, Jain RK. Nonlinear microscopy of living tumors and their treatment 2006 3rd Ieee International Symposium On Biomedical Imaging: From Nano to Macro - Proceedings. 2006: 367-370.  0.96
2005 Tyrrell JA, Mahadevan V, Tong RT, Brown EB, Jain RK, Roysam B. A 2-D/3-D model-based method to quantify the complexity of microvasculature imaged by in vivo multiphoton microscopy. Microvascular Research. 70: 165-78. PMID 16239015 DOI: 10.1016/j.mvr.2005.08.005  0.96
2005 Stroh M, Zimmer JP, Duda DG, Levchenko TS, Cohen KS, Brown EB, Scadden DT, Torchilin VP, Bawendi MG, Fukumura D, Jain RK. Quantum dots spectrally distinguish multiple species within the tumor milieu in vivo. Nature Medicine. 11: 678-82. PMID 15880117 DOI: 10.1038/nm1247  0.96
2005 Mahadevan V, Tyrrell JA, Tong RT, Brown EB, Jain RK, Roysam B. Complexity analysis of angiogenesis vasculature Progress in Biomedical Optics and Imaging - Proceedings of Spie. 5747: 526-536. DOI: 10.1117/12.596016  0.96
2004 Duda DG, Fukumura D, Munn LL, Booth MF, Brown EB, Huang P, Seed B, Jain RK. Differential transplantability of tumor-associated stromal cells. Cancer Research. 64: 5920-4. PMID 15342367 DOI: 10.1158/0008-5472.CAN-04-1268  0.96
2004 Brown EB, Boucher Y, Nasser S, Jain RK. Measurement of macromolecular diffusion coefficients in human tumors. Microvascular Research. 67: 231-6. PMID 15121448 DOI: 10.1016/j.mvr.2004.02.001  0.96
2004 Garkavtsev I, Kozin SV, Chernova O, Xu L, Winkler F, Brown E, Barnett GH, Jain RK. The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis Nature. 428: 328-332. PMID 15029197 DOI: 10.1038/nature02329  0.96
2004 Alexandrakis G, Brown EB, Tong RT, McKee TD, Campbell RB, Boucher Y, Jain RK. Two-photon fluorescence correlation microscopy reveals the two-phase nature of transport in tumors. Nature Medicine. 10: 203-7. PMID 14716306 DOI: 10.1038/nm981  0.96
2004 Tyrrell JA, Mahadevan V, Tong R, Roysam B, Brown EB, Jain RK. Robust parametric modeling for improved segmentation of complex tumor microvasculature from multiphoton microscopy data Microscopy and Microanalysis. 10: 176-177. DOI: 10.1017/S1431927604885787  0.96
2003 Znati CA, Rosenstein M, McKee TD, Brown E, Turner D, Bloomer WD, Watkins S, Jain RK, Boucher Y. Irradiation reduces interstitial fluid transport and increases the collagen content in tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 5508-13. PMID 14654530  0.96
2003 Abdul-Karim MA, Al-Kofahi K, Brown EB, Jain RK, Roysam B. Automated tracing and change analysis of angiogenic vasculature from in vivo multiphoton confocal image time series. Microvascular Research. 66: 113-25. PMID 12935769 DOI: 10.1016/S0026-2862(03)00039-6  0.96
2003 Brown E, McKee T, diTomaso E, Pluen A, Seed B, Boucher Y, Jain RK. Dynamic imaging of collagen and its modulation in tumors in vivo using second-harmonic generation. Nature Medicine. 9: 796-800. PMID 12754503 DOI: 10.1038/nm879  0.96
2003 Schmidt H, Brown EB, Schwaller B, Eilers J. Diffusional mobility of parvalbumin in spiny dendrites of cerebellar Purkinje neurons quantified by fluorescence recovery after photobleaching. Biophysical Journal. 84: 2599-608. PMID 12668468 DOI: 10.1016/S0006-3495(03)75065-6  0.96
2003 Wei X, Henke VG, Strübing C, Brown EB, Clapham DE. Real-time imaging of nuclear permeation by EGFP in single intact cells. Biophysical Journal. 84: 1317-27. PMID 12547812 DOI: 10.1016/S0006-3495(03)74947-9  0.96
2003 Abdul-Karim MA, Al-Kofahi O, Brown EB, Jain RK, Al-Kofahi K, Roysam B. Automated in vivo change analysis of tumor vasculature from two-photon confocal image time series Proceedings of Spie - the International Society For Optical Engineering. 4963: 151-159. DOI: 10.1117/12.477991  0.96
2003 Abdul-Karim MA, Al-Kofahi K, Brown EB, Jain RK, Roysam B. Automated change analysis of registered angiogenic vasculature images from in vivo multiphoton time series images Microscopy and Microanalysis. 9: 1150-1151.  0.96
2002 Campbell RB, Fukumura D, Brown EB, Mazzola LM, Izumi Y, Jain RK, Torchilin VP, Munn LL. Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors. Cancer Research. 62: 6831-6. PMID 12460895  0.96
2002 Migliorini C, Qian Y, Chen H, Brown EB, Jain RK, Munn LL. Red blood cells augment leukocyte rolling in a virtual blood vessel. Biophysical Journal. 83: 1834-41. PMID 12324405 DOI: 10.1016/S0006-3495(02)73948-9  0.96
2002 Ramanujan S, Pluen A, McKee TD, Brown EB, Boucher Y, Jain RK. Diffusion and convection in collagen gels: implications for transport in the tumor interstitium. Biophysical Journal. 83: 1650-60. PMID 12202388 DOI: 10.1016/S0006-3495(02)73933-7  0.96
2002 Padera TP, Kadambi A, di Tomaso E, Carreira CM, Brown EB, Boucher Y, Choi NC, Mathisen D, Wain J, Mark EJ, Munn LL, Jain RK. Lymphatic metastasis in the absence of functional intratumor lymphatics. Science (New York, N.Y.). 296: 1883-6. PMID 11976409 DOI: 10.1126/science.1071420  0.96
2001 Brown EB, Campbell RB, Tsuzuki Y, Xu L, Carmeliet P, Fukumura D, Jain RK. In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy. Nature Medicine. 7: 864-8. PMID 11433354 DOI: 10.1038/89997  0.96
2001 Pluen A, Boucher Y, Ramanujan S, McKee TD, Gohongi T, di Tomaso E, Brown EB, Izumi Y, Campbell RB, Berk DA, Jain RK. Role of tumor-host interactions in interstitial diffusion of macromolecules: cranial vs. subcutaneous tumors. Proceedings of the National Academy of Sciences of the United States of America. 98: 4628-33. PMID 11274375 DOI: 10.1073/pnas.081626898  0.96
2001 Brown EB, Campbell RB, Tsuzuki Y, Fukumura D, Jain RK. Measurement of physiological parameters in tumors in vivo using MPLSM Proceedings of Spie - the International Society For Optical Engineering. 4262: 134-145. DOI: 10.1117/12.424547  0.96
2000 Majewska A, Brown E, Ross J, Yuste R. Mechanisms of calcium decay kinetics in hippocampal spines: role of spine calcium pumps and calcium diffusion through the spine neck in biochemical compartmentalization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 1722-34. PMID 10684874  0.96
1999 Brown EB, Wu ES, Zipfel W, Webb WW. Measurement of molecular diffusion in solution by multiphoton fluorescence photobleaching recovery. Biophysical Journal. 77: 2837-49. PMID 10545381  0.96
1999 Brown EB, Shear JB, Adams SR, Tsien RY, Webb WW. Photolysis of caged calcium in femtoliter volumes using two-photon excitation. Biophysical Journal. 76: 489-99. PMID 9876162 DOI: 10.1016/S0006-3495(99)77217-6  0.96
1998 Brown EB, Webb WW. Two-photon activation of caged calcium with submicron, submillisecond resolution. Methods in Enzymology. 291: 356-80. PMID 9661159 DOI: 10.1016/S0076-6879(98)91023-0  0.96
1996 Shear JB, Brown EB, Webb WW. Multiphoton-excited fluorescence of fluorogen-labeled neurotransmitters. Analytical Chemistry. 68: 1778-83. PMID 8651483  0.96
1973 Hermance WE, Brown EB. Cromolyn sodium (disodium cromoglycate) in treatment of asthma. New York State Journal of Medicine. 73: 430-4. PMID 4631154  0.01
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