Yuansheng Yang, Ph.D. - Publications

Affiliations: 
2005 Vanderbilt University, Nashville, TN 
Area:
Chemical Engineering

41/70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Sim KH, Liu LC, Tan HT, Tan K, Ng D, Zhang W, Yang Y, Tate S, Bi X. A comprehensive CHO SWATH-MS spectral library for robust quantitative profiling of 10,000 proteins. Scientific Data. 7: 263. PMID 32782267 DOI: 10.1038/S41597-020-00594-Z  0.362
2019 Xu N, Ou J, Si Y, Goh KY, Flanigan DD, Han X, Yang Y, Yang S, Zhou L, Liu X(. Proteomics insight into the production of monoclonal antibody Biochemical Engineering Journal. 145: 177-185. DOI: 10.1016/J.Bej.2019.02.022  0.467
2018 Yeo JHM, Mariati, Yang Y. An IRES-Mediated Tricistronic Vector for Efficient Generation of Stable, High-Level Monoclonal Antibody Producing CHO DG44 Cell Lines. Methods in Molecular Biology (Clifton, N.J.). 1827: 335-349. PMID 30196505 DOI: 10.1007/978-1-4939-8648-4_17  0.373
2018 Hong JK, Nargund S, Lakshmanan M, Kyriakopoulos S, Kim DY, Ang KS, Leong D, Yang Y, Lee DY. Comparative phenotypic analysis of CHO clones and culture media for lactate shift. Journal of Biotechnology. PMID 30076878 DOI: 10.1016/J.Jbiotec.2018.07.042  0.45
2018 Tan HL, Yong C, Tan BZ, Fong WJ, Padmanabhan J, Chin A, Ding V, Lau A, Zheng L, Bi X, Yang Y, Choo A. Conservation of oncofetal antigens on human embryonic stem cells enables discovery of monoclonal antibodies against cancer. Scientific Reports. 8: 11608. PMID 30072783 DOI: 10.1038/S41598-018-30070-Z  0.316
2018 Cua S, Tan HL, Fong WJ, Chin A, Lau A, Ding V, Song Z, Yang Y, Choo A. Targeting of embryonic annexin A2 expressed on ovarian and breast cancer by the novel monoclonal antibody 2448. Oncotarget. 9: 13206-13221. PMID 29568351 DOI: 10.18632/Oncotarget.24152  0.325
2017 Yeo JHM, Ho SCL, Mariati M, Koh E, Tay SJ, Woen S, Zhang P, Yang Y. Optimized Selection Marker and CHO Host Cell Combinations for Generating High Monoclonal Antibody Producing Cell Lines. Biotechnology Journal. PMID 29090854 DOI: 10.1002/Biot.201700175  0.429
2017 Soo BPC, Tay J, Ng S, Ho SCL, Yang Y, Chao SH. Correlation Between Expression of Recombinant Proteins and Abundance of H3K4Me3 on the Enhancer of Human Cytomegalovirus Major Immediate-Early Promoter. Molecular Biotechnology. PMID 28664508 DOI: 10.1007/S12033-017-0019-6  0.38
2017 Yusufi FNK, Lakshmanan M, Ho YS, Loo BLW, Ariyaratne P, Yang Y, Ng SK, Tan TRM, Yeo HC, Lim HL, Ng SW, Hiu AP, Chow CP, Wan C, Chen S, et al. Mammalian Systems Biotechnology Reveals Global Cellular Adaptations in a Recombinant CHO Cell Line. Cell Systems. 4: 530-542.e6. PMID 28544881 DOI: 10.1016/J.Cels.2017.04.009  0.444
2016 Chen Q, Toh P, Hoi A, Xian M, Peng X, Yang Y, Zhang H, Nian R, Zhang W. [Improved protein-A chromatography for monoclonal antibody purification]. Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology. 32: 807-818. PMID 29019189 DOI: 10.13345/J.Cjb.160137  0.38
2016 Ho SC, Koh EY, Soo BP, Mariati, Chao SH, Yang Y. Evaluating the use of a CpG free promoter for long-term recombinant protein expression stability in Chinese hamster ovary cells. Bmc Biotechnology. 16: 71. PMID 27756290 DOI: 10.1186/S12896-016-0300-Y  0.373
2016 Ho SC, Nian R, Woen S, Chng J, Zhang P, Yang Y. Impact of hydrolysates on monoclonal antibody productivity, purification and quality in Chinese hamster ovary cells. Journal of Bioscience and Bioengineering. PMID 27067279 DOI: 10.1016/J.Jbiosc.2016.03.003  0.45
2016 Zhang P, Woen S, Wang T, Liau B, Zhao S, Chen C, Yang Y, Song Z, Wormald MR, Yu C, Rudd PM. Challenges of glycosylation analysis and control: an integrated approach to producing optimal and consistent therapeutic drugs. Drug Discovery Today. PMID 26821133 DOI: 10.1016/J.Drudis.2016.01.006  0.35
2015 Chan KF, Shahreel W, Wan C, Teo G, Hayati N, Tay SJ, Tong WH, Yang Y, Rudd PM, Zhang P, Song Z. Inactivation of GDP-fucose transporter gene (Slc35c1) in CHO cells by ZFNs, TALENs and CRISPR-Cas9 for production of fucose-free antibodies. Biotechnology Journal. PMID 26471004 DOI: 10.1002/Biot.201500331  0.399
2015 Gagnon P, Nian R, Yang Y, Yang Q, Lim CL. Non-immunospecific association of immunoglobulin G with chromatin during elution from protein A inflates host contamination, aggregate content, and antibody loss. Journal of Chromatography. A. PMID 26187767 DOI: 10.1016/J.Chroma.2015.07.017  0.302
2015 Tan L, Yeo V, Yang Y, Gagnon P. Characterization of DNA in cell culture supernatant by fluorescence-detection size-exclusion chromatography. Analytical and Bioanalytical Chemistry. 407: 4173-81. PMID 25821116 DOI: 10.1007/S00216-015-8639-9  0.371
2015 Ho SC, Wang T, Song Z, Yang Y. IgG Aggregation Mechanism for CHO Cell Lines Expressing Excess Heavy Chains. Molecular Biotechnology. 57: 625-34. PMID 25744439 DOI: 10.1007/S12033-015-9852-7  0.409
2015 Chng J, Wang T, Nian R, Lau A, Hoi KM, Ho SC, Gagnon P, Bi X, Yang Y. Cleavage efficient 2A peptides for high level monoclonal antibody expression in CHO cells. Mabs. 7: 403-12. PMID 25621616 DOI: 10.1080/19420862.2015.1008351  0.331
2015 Ho SC, Mariati, Yeo JH, Fang SG, Yang Y. Impact of using different promoters and matrix attachment regions on recombinant protein expression level and stability in stably transfected CHO cells. Molecular Biotechnology. 57: 138-44. PMID 25307181 DOI: 10.1007/S12033-014-9809-2  0.357
2014 Mariati, Koh EY, Yeo JH, Ho SC, Yang Y. Toward stable gene expression in CHO cells. Bioengineered. 5: 340-5. PMID 25482237 DOI: 10.4161/Bioe.32111  0.368
2014 Gagnon P, Nian R, Tan L, Cheong J, Yeo V, Yang Y, Gan HT. Chromatin-mediated depression of fractionation performance on electronegative multimodal chromatography media, its prevention, and ramifications for purification of immunoglobulin G. Journal of Chromatography. A. 1374: 145-55. PMID 25481347 DOI: 10.1016/J.Chroma.2014.11.052  0.317
2014 Loh WP, Loo B, Zhou L, Zhang P, Lee DY, Yang Y, Lam KP. Overexpression of microRNAs enhances recombinant protein production in Chinese hamster ovary cells. Biotechnology Journal. 9: 1140-51. PMID 24819042 DOI: 10.1002/Biot.201400050  0.39
2014 Mariati, Yeo JH, Koh EY, Ho SC, Yang Y. Insertion of core CpG island element into human CMV promoter for enhancing recombinant protein expression stability in CHO cells. Biotechnology Progress. 30: 523-34. PMID 24789630 DOI: 10.1002/Btpr.1919  0.37
2014 Ho SC, Yang Y. Identifying and engineering promoters for high level and sustainable therapeutic recombinant protein production in cultured mammalian cells. Biotechnology Letters. 36: 1569-79. PMID 24737078 DOI: 10.1007/S10529-014-1523-4  0.433
2014 Gagnon P, Nian R, Lee J, Tan L, Latiff SMA, Lim CL, Chuah C, Bi X, Yang Y, Zhang W, Gan HT. Nonspecific interactions of chromatin with immunoglobulin G and protein A, and their impact on purification performance Journal of Chromatography A. 1340: 68-78. PMID 24661871 DOI: 10.1016/J.Chroma.2014.03.010  0.326
2013 Koh EY, Ho SC, Mariati, Song Z, Bi X, Bardor M, Yang Y. An internal ribosome entry site (IRES) mutant library for tuning expression level of multiple genes in mammalian cells. Plos One. 8: e82100. PMID 24349195 DOI: 10.1371/Journal.Pone.0082100  0.387
2013 Lai T, Yang Y, Ng SK. Advances in Mammalian cell line development technologies for recombinant protein production. Pharmaceuticals (Basel, Switzerland). 6: 579-603. PMID 24276168 DOI: 10.3390/Ph6050579  0.435
2013 Chung BK, Yusufi FN, Mariati, Yang Y, Lee DY. Enhanced expression of codon optimized interferon gamma in CHO cells. Journal of Biotechnology. 167: 326-33. PMID 23876479 DOI: 10.1016/J.Jbiotec.2013.07.011  0.357
2013 Ho SC, Bardor M, Li B, Lee JJ, Song Z, Tong YW, Goh LT, Yang Y. Comparison of internal ribosome entry site (IRES) and Furin-2A (F2A) for monoclonal antibody expression level and quality in CHO cells. Plos One. 8: e63247. PMID 23704898 DOI: 10.1371/Journal.Pone.0063247  0.371
2012 Lee J, Gan HT, Latiff SMA, Chuah C, Lee WY, Yang YS, Loo B, Ng SK, Gagnon P. Principles and applications of steric exclusion chromatography Journal of Chromatography A. 1270: 162-170. PMID 23182281 DOI: 10.1016/J.Chroma.2012.10.062  0.338
2012 Ho SC, Bardor M, Feng H, Mariati, Tong YW, Song Z, Yap MG, Yang Y. IRES-mediated Tricistronic vectors for enhancing generation of high monoclonal antibody expressing CHO cell lines. Journal of Biotechnology. 157: 130-9. PMID 22024589 DOI: 10.1016/J.Jbiotec.2011.09.023  0.431
2012 Mariati, Ho SC, Yap MG, Yang Y. Post-transcriptional regulatory elements for enhancing transient gene expression levels in mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 801: 125-35. PMID 21987251 DOI: 10.1007/978-1-61779-352-3_9  0.379
2011 Feng HT, Sim LC, Wan C, Wong NS, Yang Y. Rapid characterization of protein productivity and production stability of CHO cells by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 25: 1407-12. PMID 21504006 DOI: 10.1002/Rcm.5011  0.427
2010 Zhang P, Tan DL, Heng D, Wang T, Mariati, Yang Y, Song Z. A functional analysis of N-glycosylation-related genes on sialylation of recombinant erythropoietin in six commonly used mammalian cell lines. Metabolic Engineering. 12: 526-36. PMID 20826224 DOI: 10.1016/J.Ymben.2010.08.004  0.426
2010 Yang Y, Mariati, Chusainow J, Yap MG. DNA methylation contributes to loss in productivity of monoclonal antibody-producing CHO cell lines. Journal of Biotechnology. 147: 180-5. PMID 20430058 DOI: 10.1016/J.Jbiotec.2010.04.004  0.418
2010 Mariati, Ng YK, Chao SH, Yap MG, Yang Y. Evaluating regulatory elements of human cytomegalovirus major immediate early gene for enhancing transgene expression levels in CHO K1 and HEK293 cells. Journal of Biotechnology. 147: 160-3. PMID 20416345 DOI: 10.1016/J.Jbiotec.2010.02.022  0.388
2010 Mariati, Ho SC, Yap MG, Yang Y. Evaluating post-transcriptional regulatory elements for enhancing transient gene expression levels in CHO K1 and HEK293 cells. Protein Expression and Purification. 69: 9-15. PMID 19899222 DOI: 10.1016/J.Pep.2009.08.010  0.377
2009 Yang Y, Ho SC, Yap MG. Mutated polyadenylation signals for controlling expression levels of multiple genes in mammalian cells. Biotechnology and Bioengineering. 102: 1152-60. PMID 18973284 DOI: 10.1002/Bit.22152  0.37
2004 Yang Y, Balcarcel RR. 96-well plate assay for sublethal metabolic activity. Assay and Drug Development Technologies. 2: 353-61. PMID 15357916 DOI: 10.1089/Adt.2004.2.353  0.691
2004 Yang Y, Balcarcel RR. Determination of carbon dioxide production rates for mammalian cells in 24-well plates. Biotechniques. 36: 286-90, 292, 294-5. PMID 14989093 DOI: 10.2144/04362Rr03  0.694
2003 Yang Y, Balcarcel RR. 24-well plate spectrophotometric assay for preliminary screening of metabolic activity. Assay and Drug Development Technologies. 1: 461-8. PMID 15090183 DOI: 10.1089/154065803322163777  0.701
Low-probability matches (unlikely to be authored by this person)
2017 Loh WP, Yang Y, Lam KP. miR-92a enhances recombinant protein productivity in CHO cells by increasing intracellular cholesterol levels. Biotechnology Journal. PMID 28146316 DOI: 10.1002/Biot.201600488  0.298
2013 Mueller M, Loh MQ, Tee DH, Yang Y, Jungbauer A. Liquid formulations for long-term storage of monoclonal IgGs. Applied Biochemistry and Biotechnology. 169: 1431-48. PMID 23315232 DOI: 10.1007/S12010-012-0084-Z  0.289
2013 Ho SC, Koh EY, van Beers M, Mueller M, Wan C, Teo G, Song Z, Tong YW, Bardor M, Yang Y. Control of IgG LC:HC ratio in stably transfected CHO cells and study of the impact on expression, aggregation, glycosylation and conformational stability. Journal of Biotechnology. 165: 157-66. PMID 23583871 DOI: 10.1016/J.Jbiotec.2013.03.019  0.288
2013 Nian R, Chuah C, Lee J, Gan HT, Latiff SMA, Lee WY, Vagenende V, Yang YS, Gagnon P. Void exclusion of antibodies by grafted-ligand porous particle anion exchangers Journal of Chromatography A. 1282: 127-132. PMID 23422893 DOI: 10.1016/J.Chroma.2013.01.065  0.285
2017 Lin J, Neo SH, Ho SCL, Yeo JHM, Wang T, Zhang W, Bi X, Chao SH, Yang Y. Impact of Signal Peptides on Furin-2A Mediated Monoclonal Antibody Secretion in CHO Cells. Biotechnology Journal. PMID 28727292 DOI: 10.1002/Biot.201700268  0.277
2015 Haryadi R, Ho S, Kok YJ, Pu HX, Zheng L, Pereira NA, Li B, Bi X, Goh LT, Yang Y, Song Z. Optimization of heavy chain and light chain signal peptides for high level expression of therapeutic antibodies in CHO cells. Plos One. 10: e0116878. PMID 25706993 DOI: 10.1371/Journal.Pone.0116878  0.273
2015 Nian R, Zhang W, Tan L, Lee J, Bi X, Yang Y, Gan HT, Gagnon P. Advance chromatin extraction improves capture performance of protein A affinity chromatography. Journal of Chromatography. A. PMID 26774119 DOI: 10.1016/J.Chroma.2015.12.044  0.268
2023 Nguyen NTB, Leung HW, Pang KT, Tay SJ, Walsh I, Choo ABH, Yang Y. Optimizing effector functions of monoclonal antibodies via tailored N-glycan engineering using a dual landing pad CHO targeted integration platform. Scientific Reports. 13: 15620. PMID 37731040 DOI: 10.1038/s41598-023-42925-1  0.267
2022 Huo J, Huang Y, Zheng Z, Tay XN, Mahfut FB, Zhang W, Lam KP, Yang Y, Xu S. Development of a T cell-redirecting bispecific antibody targeting B-cell maturation antigen for the suppression of multiple myeloma cell growth. Antibody Therapeutics. 5: 138-149. PMID 35774245 DOI: 10.1093/abt/tbac012  0.226
2021 Wang Z, Guan D, Huo J, Biswas SK, Huang Y, Yang Y, Xu S, Lam KP. IL-10 Enhances Human Natural Killer Cell Effector Functions via Metabolic Reprogramming Regulated by mTORC1 Signaling. Frontiers in Immunology. 12: 619195. PMID 33708210 DOI: 10.3389/fimmu.2021.619195  0.207
2022 Ong HK, Nguyen NTB, Bi J, Yang Y. Vector design for enhancing expression level and assembly of knob-into-hole based FabscFv-Fc bispecific antibodies in CHO cells. Antibody Therapeutics. 5: 288-300. PMID 36518226 DOI: 10.1093/abt/tbac025  0.201
2021 Nguyen NTB, Lin J, Tay SJ, Mariati, Yeo J, Nguyen-Khuong T, Yang Y. Multiplexed engineering glycosyltransferase genes in CHO cells via targeted integration for producing antibodies with diverse complex-type N-glycans. Scientific Reports. 11: 12969. PMID 34155258 DOI: 10.1038/s41598-021-92320-x  0.201
2024 Deng Y, Liu J, Lu Y, Fan X, Yang Y, Xu Y, Qin X, Nian R, Liu W. Novel Polystyrene-Binding Nanobody for Enhancing Immunoassays: Insights into Affinity, Immobilization, and Application Potential. Analytical Chemistry. PMID 38235613 DOI: 10.1021/acs.analchem.3c04375  0.19
2023 Loh HP, Mahfut FB, Chen SW, Huang Y, Huo J, Zhang W, Lam KP, Xu S, Yang Y. Manufacturability and functionality assessment of different formats of T-cell engaging bispecific antibodies. Mabs. 15: 2231129. PMID 37403264 DOI: 10.1080/19420862.2023.2231129  0.185
2023 Chen SW, Zheng ZY, Mahfut FB, Yang Y, Ogino M, Okada K, Sato K, Zhang W. Leveraging an advanced simulated moving bed approach to achieve 3-component separation for enhanced impurity removal in a non-affinity cation exchange capture step. Plos One. 18: e0280760. PMID 36696419 DOI: 10.1371/journal.pone.0280760  0.183
2015 Wang J, Witte F, Xi T, Zheng Y, Yang K, Yang Y, Zhao D, Meng J, Li Y, Li W, Chan K, Qin L. Recommendation for modifying current cytotoxicity testing standards for biodegradable magnesium-based materials. Acta Biomaterialia. 21: 237-49. PMID 25890098 DOI: 10.1016/J.Actbio.2015.04.011  0.154
2023 Chia S, Tay SJ, Song Z, Yang Y, Walsh I, Pang KT. Enhancing pharmacokinetic and pharmacodynamic properties of recombinant therapeutic proteins by manipulation of sialic acid content. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 163: 114757. PMID 37087980 DOI: 10.1016/j.biopha.2023.114757  0.136
2006 Yang Y, Chusainow J, Mao Y, Ho SC, Yap MG. Microbial Cell Factories. 5: P3. DOI: 10.1186/1475-2859-5-S1-P3  0.12
2010 Lin X, Sun L, Li Y, Guo Z, Li Y, Zhong K, Wang Q, Lu X, Yang Y, Xu G. A random forest of combined features in the classification of cut tobacco based on gas chromatography fingerprinting. Talanta. 82: 1571-5. PMID 20801374 DOI: 10.1016/j.talanta.2010.07.053  0.1
2013 Yang YS, Chen K, Ye S, Shi XL, Du ZW, Cui SL, Wang H. [Differentially expressed proteins of severe acute pancreatitis intervened by Qingyi granule]. Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine / Zhongguo Zhong Xi Yi Jie He Xue Hui, Zhongguo Zhong Yi Yan Jiu Yuan Zhu Ban. 33: 60-4. PMID 23596789  0.081
2023 Tee JH, Vijayakumar U, Shanmugasundaram M, Lam TYW, Liao W, Yang Y, Wong WSF, Ge R. Isthmin-1 attenuates allergic Asthma by stimulating adiponectin expression and alveolar macrophage efferocytosis in mice. Respiratory Research. 24: 269. PMID 37932719 DOI: 10.1186/s12931-023-02569-1  0.075
2019 Mao Y, Yang Y. A Wrapper Feature Subset Selection Method Based on Randomized Search and Multilayer Structure. Biomed Research International. 2019: 9864213. PMID 31828154 DOI: 10.1155/2019/9864213  0.061
2018 Chen Y, Song X, Zhou J, Liu H, Yang Y. The Study on the Overall Plasma Electrolytic Oxidation for 6061-7075 Dissimilar Aluminum Alloy Welded Parts Based on the Dielectric Breakdown Theory. Materials (Basel, Switzerland). 11. PMID 29301306 DOI: 10.3390/ma11010063  0.044
2015 Yang YS, Chen K, Xie WR, Wang H. [Effect of Qingyi Granule on HMGB1 Expression in Liver and Renal Tissues of Severe Acute Pancreatitis Rats]. Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine / Zhongguo Zhong Xi Yi Jie He Xue Hui, Zhongguo Zhong Yi Yan Jiu Yuan Zhu Ban. 35: 1367-72. PMID 26775487  0.042
2010 Yang YS, Yen JY, Ko CH, Cheng CP, Yen CF. The association between problematic cellular phone use and risky behaviors and low self-esteem among Taiwanese adolescents. Bmc Public Health. 10: 217. PMID 20426807 DOI: 10.1186/1471-2458-10-217  0.04
2020 Jia H, Feng X, Yang Y. Effect of grain morphology on the degradation behavior of Mg-4 wt% Zn alloy in Hank's solution. Materials Science & Engineering. C, Materials For Biological Applications. 106: 110013. PMID 31753338 DOI: 10.1016/j.msec.2019.110013  0.038
2018 Feng X, Zhao F, Jia H, Li Y, Yang Y. Numerical simulation of non-dendritic structure formation in Mg-Al alloy solidified with ultrasonic field. Ultrasonics Sonochemistry. 40: 113-119. PMID 28946404 DOI: 10.1016/j.ultsonch.2017.07.006  0.037
2021 Xie H, Huang Q, Bai J, Li S, Liu Y, Feng J, Yang Y, Pan H, Li H, Ren Y, Qin G. Nonsymmetrical Segregation of Solutes in Periodic Misfit Dislocations Separated Tilt Grain Boundaries. Nano Letters. PMID 33755476 DOI: 10.1021/acs.nanolett.0c05008  0.034
2022 Zheng C, Xu L, Feng X, Huang Q, Li Y, Zhang Z, Yang Y. Influence of Grain Orientation and Grain Boundary Features on Local Stress State of Cu-8Al-11Mn Alloy Investigated Using Crystal Plasticity Finite Element Method. Materials (Basel, Switzerland). 15. PMID 36234291 DOI: 10.3390/ma15196950  0.023
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