Year |
Citation |
Score |
2024 |
Kawakami N, Wekerle H. Life history of a brain autoreactive T cell: From thymus through intestine to blood-brain barrier and brain lesion. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. e00442. PMID 39237437 DOI: 10.1016/j.neurot.2024.e00442 |
0.406 |
|
2023 |
Thomann AS, McQuade CA, Pinjušić K, Kolz A, Schmitz R, Kitamura D, Wekerle H, Peters A. A B cell-driven EAE mouse model reveals the impact of B cell-derived cytokines on CNS autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 120: e2300733120. PMID 37956299 DOI: 10.1073/pnas.2300733120 |
0.366 |
|
2023 |
Bauer IJ, Fang P, Lämmle KF, Tyystjärvi S, Alterauge D, Baumjohann D, Yoon H, Korn T, Wekerle H, Kawakami N. Visualizing the activation of encephalitogenic T cells in the ileal lamina propria by in vivo two-photon imaging. Proceedings of the National Academy of Sciences of the United States of America. 120: e2302697120. PMID 37467267 DOI: 10.1073/pnas.2302697120 |
0.389 |
|
2018 |
Wekerle H. Nature, nurture, and microbes: The development of multiple sclerosis. Acta Neurologica Scandinavica. 22-25. PMID 29068487 DOI: 10.1111/ane.12843 |
0.355 |
|
2017 |
Kyratsous NI, Bauer IJ, Zhang G, Pesic M, Bartholomäus I, Mues M, Fang P, Wörner M, Everts S, Ellwart JW, Watt JM, Potter BVL, Hohlfeld R, Wekerle H, Kawakami N. Visualizing context-dependent calcium signaling in encephalitogenic T cells in vivo by two-photon microscopy. Proceedings of the National Academy of Sciences of the United States of America. PMID 28716943 DOI: 10.1073/Pnas.1701806114 |
0.372 |
|
2017 |
Wekerle H. Brain Autoimmunity and Intestinal Microbiota: 100 Trillion Game Changers. Trends in Immunology. PMID 28601415 DOI: 10.1016/j.it.2017.03.008 |
0.302 |
|
2017 |
Wekerle H. B cells in multiple sclerosis. Autoimmunity. 50: 57-60. PMID 28166681 DOI: 10.1080/08916934.2017.1281914 |
0.343 |
|
2015 |
Hohlfeld R, Dornmair K, Meinl E, Wekerle H. The search for the target antigens of multiple sclerosis, part 2: CD8+ T cells, B cells, and antibodies in the focus of reverse-translational research. The Lancet. Neurology. PMID 26724102 DOI: 10.1016/S1474-4422(15)00313-0 |
0.309 |
|
2015 |
Held K, Bhonsle-Deeng L, Siewert K, Sato W, Beltrán E, Schmidt S, Rühl G, Ng JK, Engerer P, Moser M, Klinkert WE, Babbe H, Misgeld T, Wekerle H, Laplaud DA, et al. αβ T-cell receptors from multiple sclerosis brain lesions show MAIT cell-related features. Neurology® Neuroimmunology & Neuroinflammation. 2: e107. PMID 25977934 DOI: 10.1212/NXI.0000000000000107 |
0.362 |
|
2014 |
Koutrolos M, Berer K, Kawakami N, Wekerle H, Krishnamoorthy G. Treg cells mediate recovery from EAE by controlling effector T cell proliferation and motility in the CNS. Acta Neuropathologica Communications. 2: 163. PMID 25476447 DOI: 10.1186/s40478-014-0163-1 |
0.415 |
|
2014 |
Kawakami N, Pesic M, Mues M, Bartholomäus I, Kyratsous N, Wekerle H. Intravital imaging of T cell activation in the CNS during autoimmunity Journal of Neuroimmunology. 275: 201. DOI: 10.1016/j.jneuroim.2014.08.540 |
0.327 |
|
2013 |
Pohl M, Kawakami N, Kitic M, Bauer J, Martins R, Fischer MT, Machado-Santos J, Mader S, Ellwart JW, Misu T, Fujihara K, Wekerle H, Reindl M, Lassmann H, Bradl M. T cell-activation in neuromyelitis optica lesions plays a role in their formation. Acta Neuropathologica Communications. 1: 85. PMID 24367907 DOI: 10.1186/2051-5960-1-85 |
0.407 |
|
2013 |
Mues M, Bartholomäus I, Thestrup T, Griesbeck O, Wekerle H, Kawakami N, Krishnamoorthy G. Real-time in vivo analysis of T cell activation in the central nervous system using a genetically encoded calcium indicator. Nature Medicine. 19: 778-83. PMID 23685843 DOI: 10.1038/nm.3180 |
0.335 |
|
2013 |
Pesic M, Bartholomäus I, Kyratsous NI, Heissmeyer V, Wekerle H, Kawakami N. 2-photon imaging of phagocyte-mediated T cell activation in the CNS. The Journal of Clinical Investigation. 123: 1192-201. PMID 23454769 DOI: 10.1172/JCI67233 |
0.396 |
|
2012 |
Odoardi F, Sie C, Streyl K, Ulaganathan VK, Schläger C, Lodygin D, Heckelsmiller K, Nietfeld W, Ellwart J, Klinkert WE, Lottaz C, Nosov M, Brinkmann V, Spang R, Lehrach H, ... ... Wekerle H, et al. T cells become licensed in the lung to enter the central nervous system. Nature. 488: 675-9. PMID 22914092 DOI: 10.1038/Nature11337 |
0.392 |
|
2011 |
Liblau RS, Wekerle H, Tisch RM. Cumulative autoimmunity: T cell clones recognizing several self-epitopes exhibit enhanced pathogenicity. Frontiers in Immunology. 2: 47. PMID 22566837 DOI: 10.3389/Fimmu.2011.00047 |
0.304 |
|
2011 |
Berer K, Mues M, Koutrolos M, Rasbi ZA, Boziki M, Johner C, Wekerle H, Krishnamoorthy G. Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination. Nature. 479: 538-41. PMID 22031325 DOI: 10.1038/nature10554 |
0.348 |
|
2009 |
Bartholomäus I, Kawakami N, Odoardi F, Schläger C, Miljkovic D, Ellwart JW, Klinkert WE, Flügel-Koch C, Issekutz TB, Wekerle H, Flügel A. Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions. Nature. 462: 94-8. PMID 19829296 DOI: 10.1038/nature08478 |
0.398 |
|
2009 |
Pöllinger B, Krishnamoorthy G, Berer K, Lassmann H, Bösl MR, Dunn R, Domingues HS, Holz A, Kurschus FC, Wekerle H. Spontaneous relapsing-remitting EAE in the SJL/J mouse: MOG-reactive transgenic T cells recruit endogenous MOG-specific B cells. The Journal of Experimental Medicine. 206: 1303-16. PMID 19487416 DOI: 10.1084/jem.20090299 |
0.353 |
|
2009 |
Krishnamoorthy G, Saxena A, Mars LT, Domingues HS, Mentele R, Ben-Nun A, Lassmann H, Dornmair K, Kurschus FC, Liblau RS, Wekerle H. Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis. Nature Medicine. 15: 626-32. PMID 19483694 DOI: 10.1038/Nm.1975 |
0.374 |
|
2009 |
Derfuss T, Parikh K, Velhin S, Braun M, Mathey E, Krumbholz M, Kümpfel T, Moldenhauer A, Rader C, Sonderegger P, Pöllmann W, Tiefenthaller C, Bauer J, Lassmann H, Wekerle H, et al. Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals. Proceedings of the National Academy of Sciences of the United States of America. 106: 8302-7. PMID 19416878 DOI: 10.1073/Pnas.0901496106 |
0.378 |
|
2009 |
Bauer M, Brakebusch C, Coisne C, Sixt M, Wekerle H, Engelhardt B, Fässler R. Beta1 integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 106: 1920-5. PMID 19179279 DOI: 10.1073/Pnas.0808909106 |
0.33 |
|
2008 |
Hohlfeld R, Wekerle H. Reflections on the "intrathymic pathogenesis" of myasthenia gravis. Journal of Neuroimmunology. 201: 21-7. PMID 18644632 DOI: 10.1016/j.jneuroim.2008.05.020 |
0.346 |
|
2007 |
Odoardi F, Kawakami N, Klinkert WE, Wekerle H, Flügel A. Blood-borne soluble protein antigen intensifies T cell activation in autoimmune CNS lesions and exacerbates clinical disease. Proceedings of the National Academy of Sciences of the United States of America. 104: 18625-30. PMID 18000062 DOI: 10.1073/pnas.0705033104 |
0.455 |
|
2007 |
Junker A, Ivanidze J, Malotka J, Eiglmeier I, Lassmann H, Wekerle H, Meinl E, Hohlfeld R, Dornmair K. Multiple sclerosis: T-cell receptor expression in distinct brain regions. Brain : a Journal of Neurology. 130: 2789-99. PMID 17890278 DOI: 10.1093/brain/awm214 |
0.406 |
|
2007 |
Grundtner R, Dornmair K, Dahm R, Flügel A, Kawakami N, Zeitelhofer M, Schoderboeck L, Nosov M, Selzer E, Willheim M, Kiebler M, Wekerle H, Lassmann H, Bradl M. Transition from enhanced T cell infiltration to inflammation in the myelin-degenerative central nervous system. Neurobiology of Disease. 28: 261-75. PMID 17889548 DOI: 10.1016/j.nbd.2007.05.006 |
0.449 |
|
2007 |
Wekerle H. [The enigma of arrival: [corrected] the entrance of auto-immune T lymphocytes in central nervous tissues and of their attack against the myelin structures]. Comptes Rendus Biologies. 330: 1-12. PMID 17241944 DOI: 10.1016/j.crvi.2006.10.002 |
0.392 |
|
2007 |
Odoardi F, Kawakami N, Li Z, Cordiglieri C, Streyl K, Nosov M, Klinkert WE, Ellwart JW, Bauer J, Lassmann H, Wekerle H, Flügel A. Instant effect of soluble antigen on effector T cells in peripheral immune organs during immunotherapy of autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 104: 920-5. PMID 17213317 DOI: 10.1073/pnas.0608383104 |
0.419 |
|
2006 |
Krishnamoorthy G, Lassmann H, Wekerle H, Holz A. Spontaneous opticospinal encephalomyelitis in a double-transgenic mouse model of autoimmune T cell/B cell cooperation. The Journal of Clinical Investigation. 116: 2385-92. PMID 16955140 DOI: 10.1172/JCI28330 |
0.353 |
|
2006 |
Seitz S, Schneider CK, Malotka J, Nong X, Engel AG, Wekerle H, Hohlfeld R, Dornmair K. Reconstitution of paired T cell receptor alpha- and beta-chains from microdissected single cells of human inflammatory tissues. Proceedings of the National Academy of Sciences of the United States of America. 103: 12057-62. PMID 16882720 DOI: 10.1073/pnas.0604247103 |
0.311 |
|
2006 |
Hohlfeld R, Kerschensteiner M, Stadelmann C, Lassmann H, Wekerle H. The neuroprotective effect of inflammation: implications for the therapy of multiple sclerosis. Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 27: S1-7. PMID 16708174 DOI: 10.1007/S10072-006-0537-7 |
0.419 |
|
2006 |
Wekerle H, Linington C. Organ specific autoantigens and the autoreactiveT cell repertoire: the case of myelin oligodendrocyte glycoprotein. European Journal of Immunology. 36: 512-5. PMID 16506289 DOI: 10.1002/eji.200635914 |
0.405 |
|
2005 |
Kawakami N, Odoardi F, Ziemssen T, Bradl M, Ritter T, Neuhaus O, Lassmann H, Wekerle H, Flügel A. Autoimmune CD4+ T cell memory: lifelong persistence of encephalitogenic T cell clones in healthy immune repertoires. Journal of Immunology (Baltimore, Md. : 1950). 175: 69-81. PMID 15972633 |
0.419 |
|
2005 |
Kawakami N, Nägerl UV, Odoardi F, Bonhoeffer T, Wekerle H, Flügel A. Live imaging of effector cell trafficking and autoantigen recognition within the unfolding autoimmune encephalomyelitis lesion. The Journal of Experimental Medicine. 201: 1805-14. PMID 15939794 DOI: 10.1084/jem.20050011 |
0.434 |
|
2005 |
Bradl M, Bauer J, Flügel A, Wekerle H, Lassmann H. Complementary contribution of CD4 and CD8 T lymphocytes to T-cell infiltration of the intact and the degenerative spinal cord. The American Journal of Pathology. 166: 1441-50. PMID 15855644 DOI: 10.1016/S0002-9440(10)62361-9 |
0.373 |
|
2005 |
Krumbholz M, Theil D, Derfuss T, Rosenwald A, Schrader F, Monoranu CM, Kalled SL, Hess DM, Serafini B, Aloisi F, Wekerle H, Hohlfeld R, Meinl E. BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma. The Journal of Experimental Medicine. 201: 195-200. PMID 15642740 DOI: 10.1084/jem.20041674 |
0.317 |
|
2004 |
Aboul-Enein F, Bauer J, Klein M, Schubart A, Flügel A, Ritter T, Kawakami N, Siedler F, Linington C, Wekerle H, Lassmann H, Bradl M. Selective and antigen-dependent effects of myelin degeneration on central nervous system inflammation. Journal of Neuropathology and Experimental Neurology. 63: 1284-96. PMID 15624765 |
0.37 |
|
2004 |
Skulina C, Schmidt S, Dornmair K, Babbe H, Roers A, Rajewsky K, Wekerle H, Hohlfeld R, Goebels N. Multiple sclerosis: brain-infiltrating CD8+ T cells persist as clonal expansions in the cerebrospinal fluid and blood. Proceedings of the National Academy of Sciences of the United States of America. 101: 2428-33. PMID 14983026 DOI: 10.1073/Pnas.0308689100 |
0.313 |
|
2004 |
Kawakami N, Lassmann S, Li Z, Odoardi F, Ritter T, Ziemssen T, Klinkert WE, Ellwart JW, Bradl M, Krivacic K, Lassmann H, Ransohoff RM, Volk HD, Wekerle H, Linington C, et al. The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis. The Journal of Experimental Medicine. 199: 185-97. PMID 14734524 DOI: 10.1084/jem.20031064 |
0.446 |
|
2003 |
Dornmair K, Goebels N, Weltzien HU, Wekerle H, Hohlfeld R. T-cell-mediated autoimmunity: novel techniques to characterize autoreactive T-cell receptors. The American Journal of Pathology. 163: 1215-26. PMID 14507631 DOI: 10.1016/S0002-9440(10)63481-5 |
0.366 |
|
2003 |
Hofbauer M, Wiesener S, Babbe H, Roers A, Wekerle H, Dornmair K, Hohlfeld R, Goebels N. Clonal tracking of autoaggressive T cells in polymyositis by combining laser microdissection, single-cell PCR, and CDR3-spectratype analysis. Proceedings of the National Academy of Sciences of the United States of America. 100: 4090-5. PMID 12651958 DOI: 10.1073/pnas.0236183100 |
0.345 |
|
2002 |
Wiendl H, Malotka J, Holzwarth B, Weltzien HU, Wekerle H, Hohlfeld R, Dornmair K. An autoreactive gamma delta TCR derived from a polymyositis lesion. Journal of Immunology (Baltimore, Md. : 1950). 169: 515-21. PMID 12077283 DOI: 10.4049/jimmunol.169.1.515 |
0.36 |
|
2001 |
Medana I, Martinic MA, Wekerle H, Neumann H. Transection of major histocompatibility complex class I-induced neurites by cytotoxic T lymphocytes. The American Journal of Pathology. 159: 809-15. PMID 11549572 DOI: 10.1016/S0002-9440(10)61755-5 |
0.319 |
|
2001 |
Sun D, Whitaker JN, Huang Z, Liu D, Coleclough C, Wekerle H, Raine CS. Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL/6 mice. Journal of Immunology (Baltimore, Md. : 1950). 166: 7579-87. PMID 11390514 DOI: 10.4049/Jimmunol.166.12.7579 |
0.376 |
|
2001 |
Flügel A, Berkowicz T, Ritter T, Labeur M, Jenne DE, Li Z, Ellwart JW, Willem M, Lassmann H, Wekerle H. Migratory activity and functional changes of green fluorescent effector cells before and during experimental autoimmune encephalomyelitis. Immunity. 14: 547-60. PMID 11371357 DOI: 10.1016/S1074-7613(01)00143-1 |
0.376 |
|
2000 |
Flügel A, Schwaiger FW, Neumann H, Medana I, Willem M, Wekerle H, Kreutzberg GW, Graeber MB. Neuronal FasL induces cell death of encephalitogenic T lymphocytes. Brain Pathology (Zurich, Switzerland). 10: 353-64. PMID 10885654 DOI: 10.1111/J.1750-3639.2000.Tb00267.X |
0.54 |
|
2000 |
Neuhaus O, Farina C, Yassouridis A, Wiendl H, Then Bergh F, Dose T, Wekerle H, Hohlfeld R. Multiple sclerosis: comparison of copolymer-1- reactive T cell lines from treated and untreated subjects reveals cytokine shift from T helper 1 to T helper 2 cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 7452-7. PMID 10861011 DOI: 10.1073/pnas.97.13.7452 |
0.317 |
|
2000 |
Hohlfeld R, Kerschensteiner M, Stadelmann C, Lassmann H, Wekerle H. The neuroprotective effect of inflammation: implications for the therapy of multiple sclerosis. Journal of Neuroimmunology. 107: 161-6. PMID 10854651 DOI: 10.1016/S0165-5728(00)00233-2 |
0.439 |
|
2000 |
Goebels N, Hofstetter H, Schmidt S, Brunner C, Wekerle H, Hohlfeld R. Repertoire dynamics of autoreactive T cells in multiple sclerosis patients and healthy subjects: epitope spreading versus clonal persistence. Brain : a Journal of Neurology. 123: 508-18. PMID 10686174 |
0.393 |
|
1999 |
Lindert RB, Haase CG, Brehm U, Linington C, Wekerle H, Hohlfeld R. Multiple sclerosis: B- and T-cell responses to the extracellular domain of the myelin oligodendrocyte glycoprotein. Brain : a Journal of Neurology. 122: 2089-100. PMID 10545394 DOI: 10.1093/brain/122.11.2089 |
0.419 |
|
1999 |
Kerschensteiner M, Gallmeier E, Behrens L, Leal VV, Misgeld T, Klinkert WE, Kolbeck R, Hoppe E, Oropeza-Wekerle RL, Bartke I, Stadelmann C, Lassmann H, Wekerle H, Hohlfeld R. Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation? The Journal of Experimental Medicine. 189: 865-70. PMID 10049950 DOI: 10.1084/Jem.189.5.865 |
0.375 |
|
1998 |
Bauer J, Bradl M, Hickley WF, Forss-Petter S, Breitschopf H, Linington C, Wekerle H, Lassmann H. T-cell apoptosis in inflammatory brain lesions: destruction of T cells does not depend on antigen recognition. The American Journal of Pathology. 153: 715-24. PMID 9736022 |
0.427 |
|
1998 |
Zipp F, Kerschensteiner M, Dornmair K, Malotka J, Schmidt S, Bender A, Giegerich G, de Waal Malefyt R, Wekerle H, Hohlfeld R. Diversity of the anti-T-cell receptor immune response and its implications for T-cell vaccination therapy of multiple sclerosis. Brain : a Journal of Neurology. 121: 1395-407. PMID 9712003 DOI: 10.1093/Brain/121.8.1395 |
0.344 |
|
1998 |
Kääb G, Haarmann I, Wekerle H, Bradl M. The myelin basic protein-specific T cell repertoire in Lewis rats: T cell receptor diversity is influenced both by intrathymic milieu and by extrathymic peptide presentation. European Journal of Immunology. 28: 1499-506. PMID 9603454 DOI: 10.1002/(SICI)1521-4141(199805)28:05<1499::AID-IMMU1499>3.0.CO;2-S |
0.339 |
|
1997 |
Tourbah A, Linnington C, Bachelin C, Avellana-Adalid V, Wekerle H, Baron-Van Evercooren A. Inflammation promotes survival and migration of the CG4 oligodendrocyte progenitors transplanted in the spinal cord of both inflammatory and demyelinated EAE rats. Journal of Neuroscience Research. 50: 853-61. PMID 9418972 DOI: 10.1002/(SICI)1097-4547(19971201)50:5<853::AID-JNR21>3.0.CO;2-0 |
0.305 |
|
1997 |
Schmidt S, Linington C, Zipp F, Sotgiu S, de Waal Malefyt R, Wekerle H, Hohlfeld R. Multiple sclerosis: comparison of the human T-cell response to S100 beta and myelin basic protein reveals parallels to rat experimental autoimmune panencephalitis. Brain : a Journal of Neurology. 120: 1437-45. PMID 9278633 DOI: 10.1093/brain/120.8.1437 |
0.372 |
|
1997 |
Kojima K, Wekerle H, Lassmann H, Berger T, Linington C. Induction of experimental autoimmune encephalomyelitis by CD4+ T cells specific for an astrocyte protein, S100 beta. Journal of Neural Transmission. Supplementum. 49: 43-51. PMID 9266413 |
0.384 |
|
1997 |
Kojima K, Reindl M, Lassmann H, Wekerle H, Linington C. The thymus and self-tolerance: co-existence of encephalitogenic S100 beta-specific T cells and their nominal autoantigen in the normal adult rat thymus. International Immunology. 9: 897-904. PMID 9199973 DOI: 10.1093/intimm/9.6.897 |
0.405 |
|
1997 |
Meinl E, Fickenscher H, Hoch RM, Malefyt RD, de Waal Malefyt R, t Hart BA, Wekerle H, Hohlfeld R, Fleckenstein B. Growth transformation of antigen-specific T cell lines from rhesus monkeys by herpesvirus saimiri. Virology. 229: 175-82. PMID 9123859 DOI: 10.1006/viro.1996.8427 |
0.342 |
|
1997 |
Berger T, Weerth S, Kojima K, Linington C, Wekerle H, Lassmann H. Experimental autoimmune encephalomyelitis: the antigen specificity of T lymphocytes determines the topography of lesions in the central and peripheral nervous system. Laboratory Investigation; a Journal of Technical Methods and Pathology. 76: 355-64. PMID 9121118 |
0.476 |
|
1997 |
Liu X, Linnington C, Webster HD, Lassmann S, Yao DL, Hudson LD, Wekerle H, Kreutzberg GW. Insulin-like growth factor-I treatment reduces immune cell responses in acute non-demyelinative experimental autoimmune encephalomyelitis. Journal of Neuroscience Research. 47: 531-8. PMID 9067862 DOI: 10.1002/(Sici)1097-4547(19970301)47:5<531::Aid-Jnr8>3.0.Co;2-I |
0.529 |
|
1997 |
Klinkert WE, Kojima K, Lesslauer W, Rinner W, Lassmann H, Wekerle H. TNF-alpha receptor fusion protein prevents experimental auto-immune encephalomyelitis and demyelination in Lewis rats: an overview. Journal of Neuroimmunology. 72: 163-8. PMID 9042109 DOI: 10.1016/S0165-5728(96)00183-X |
0.377 |
|
1997 |
MeinL E, Hoch RM, Dornmair K, de Waal Malefyt R, Bontrop RE, Jonker M, Lassmann H, Hohlfeld R, Wekerle H, 't Hart BA. Encephalitogenic potential of myelin basic protein-specific T cells isolated from normal rhesus macaques. The American Journal of Pathology. 150: 445-53. PMID 9033260 |
0.429 |
|
1997 |
Inomata T, Bauer J, Lassmann H, Wekerle H, Bradl M. T cell autoimmunity in the degenerating central nervous system (CNS) Immunobiology. 197: 240. |
0.413 |
|
1997 |
Medana IM, Wekerle H, Neumann H. Interactions between cytotoxic T lymphocytes and MHC class I-induced neurons: A single cell analysis Immunobiology. 197: 411-412. |
0.31 |
|
1996 |
Wekerle H, Bradl M, Linington C, Kääb G, Kojima K. The shaping of the brain-specific T lymphocyte repertoire in the thymus. Immunological Reviews. 149: 231-43. PMID 9005217 |
0.418 |
|
1996 |
Gehrmann J, Lannes-Vieira J, Wekerle H. Differential expression of fibroblast growth factor-2 and receptor by glial cells in experimental autoimmune encephalomyelitis (EAE) Glia. 16: 93-100. PMID 8929896 DOI: 10.1002/(SICI)1098-1136(199602)16:2<93::AID-GLIA1>3.0.CO;2-B |
0.395 |
|
1996 |
Gold R, Schmied M, Tontsch U, Hartung HP, Wekerle H, Toyka KV, Lassmann H. Antigen presentation by astrocytes primes rat T lymphocytes for apoptotic cell death. A model for T-cell apoptosis in vivo. Brain : a Journal of Neurology. 119: 651-9. PMID 8800954 DOI: 10.1093/Brain/119.2.651 |
0.426 |
|
1996 |
Kääb G, Brandl G, Marx A, Wekerle H, Bradl M. The myelin basic protein-specific T cell repertoire in (transgenic) Lewis rat/SCID mouse chimeras: preferential V beta 8.2 T cell receptor usage depends on an intact Lewis thymic microenvironment. European Journal of Immunology. 26: 981-8. PMID 8647189 DOI: 10.1002/eji.1830260504 |
0.388 |
|
1995 |
Meinl E, Hohlfeld R, Wekerle H, Fleckenstein B. Immortalization of human T cells by Herpesvirus saimiri. Immunology Today. 16: 55-8. PMID 7888066 DOI: 10.1016/0167-5699(95)80087-5 |
0.317 |
|
1995 |
Banati RB, Gehrmann J, Lannes-Vieira J, Wekerle H, Kreutzberg GW. Inflammatory reaction in experimental autoimmune encephalomyelitis (EAE) is accompanied by a microglial expression of the beta A4-amyloid precursor protein (APP). Glia. 14: 209-15. PMID 7591032 DOI: 10.1002/Glia.440140306 |
0.552 |
|
1995 |
Kramer R, Zhang Y, Gehrmann J, Gold R, Thoenen H, Wekerle H. Gene transfer through the blood-nerve barrier: NGF-engineered neuritogenic T lymphocytes attenuate experimental autoimmune neuritis. Nature Medicine. 1: 1162-6. PMID 7584988 DOI: 10.1038/Nm1195-1162 |
0.334 |
|
1995 |
Gehrmann J, Yao DL, Bonetti B, Brenner M, Bondy C, Wekerle H, Kreutzberg GW, Webster Hde F. Astrocytes upregulate glial fibrillary acidic protein (GFAP), but not insulin-like growth factor-I (IGF-I) during experimental autoimmune neuritis (EAN). Brain Pathology (Zurich, Switzerland). 5: 1-10. PMID 7539325 DOI: 10.1111/J.1750-3639.1995.Tb00570.X |
0.507 |
|
1995 |
Lannes-Viera J, Goudable B, Drexler K, Gehrmann J, Torres-Nagel N, Hünig T, Wekerle H. Encephalitogenic, myelin basic protein-specific T cells from naive rat thymus: preferential use of the T cell receptor gene V beta 8.2 and expression of the CD4-CD8- phenotype. European Journal of Immunology. 25: 611-6. PMID 7533094 DOI: 10.1002/eji.1830250245 |
0.331 |
|
1995 |
Meinl E, t Hart BA, Bontrop RE, Hoch RM, Iglesias A, de Waal Malefyt R, Fickenscher H, Müller-Fleckenstein I, Fleckenstein B, Wekerle H. Activation of a myelin basic protein-specific human T cell clone by antigen-presenting cells from rhesus monkeys. International Immunology. 7: 1489-95. PMID 7495756 DOI: 10.1093/intimm/7.9.1489 |
0.347 |
|
1994 |
Wekerle H, Lassmann H. Contra: evidence against a primary lesion in the target organ in autoimmune disease. International Archives of Allergy and Immunology. 103: 328-31. PMID 8130647 DOI: 10.1159/000236650 |
0.336 |
|
1994 |
Kaltschmidt C, Kaltschmidt B, Lannes-Vieira J, Kreutzberg GW, Wekerle H, Baeuerle PA, Gehrmann J. Transcription factor NF-kappa B is activated in microglia during experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. 55: 99-106. PMID 7962486 DOI: 10.1016/0165-5728(94)90151-1 |
0.467 |
|
1994 |
Meinl E, Aloisi F, Ertl B, Weber F, de Waal Malefyt R, Wekerle H, Hohlfeld R. Multiple sclerosis. Immunomodulatory effects of human astrocytes on T cells. Brain : a Journal of Neurology. 117: 1323-32. PMID 7820569 |
0.416 |
|
1994 |
Engelhardt B, Görlach H, Risau W, Wekerle H. Lysis of rat brain microvascular endothelial cells mediated by resting but not activated MBP-specific CD4+ T cell lines. Journal of Neuroimmunology. 55: 69-80. PMID 7525644 DOI: 10.1016/0165-5728(94)90148-1 |
0.426 |
|
1994 |
Kojima K, Berger T, Lassmann H, Hinze-Selch D, Zhang Y, Gehrmann J, Reske K, Wekerle H, Linington C. Experimental autoimmune panencephalitis and uveoretinitis transferred to the Lewis rat by T lymphocytes specific for the S100 beta molecule, a calcium binding protein of astroglia. The Journal of Experimental Medicine. 180: 817-29. PMID 7520474 DOI: 10.1084/jem.180.3.817 |
0.454 |
|
1994 |
Lannes-Vieira J, Gehrmann J, Kreutzberg GW, Wekerle H. The inflammatory lesion of T cell line transferred experimental autoimmune encephalomyelitis of the Lewis rat: distinct nature of parenchymal and perivascular infiltrates. Acta Neuropathologica. 87: 435-42. PMID 7520206 DOI: 10.1007/Bf00294169 |
0.57 |
|
1994 |
Wekerle H, Kojima K, Lannes-Vieira J, Lassmann H, Linington C. Animal models. Annals of Neurology. 36: S47-53. PMID 7517126 DOI: 10.1002/ana.410360714 |
0.438 |
|
1993 |
Wekerle H. T-cell autoimmunity in the central nervous system. Intervirology. 35: 95-100. PMID 8407255 DOI: 10.1159/000150299 |
0.45 |
|
1993 |
Gehrmann J, Gold R, Linington C, Lannes-Vieira J, Wekerle H, Kreutzberg GW. Microglial involvement in experimental autoimmune inflammation of the central and peripheral nervous system. Glia. 7: 50-9. PMID 8380791 DOI: 10.1002/Glia.440070110 |
0.583 |
|
1993 |
Salvetti M, Buttinelli C, Massacesi L, Wekerle H. New approaches to the study of T cell autoimmunity in multiple sclerosis. Meeting report on the 2nd Workshop on T cell Autoimmunity in MS, Perugia, Italy, 26-28 November, 1992. Journal of Neuroimmunology. 47: 203-5. PMID 8370772 DOI: 10.1016/0165-5728(93)90031-S |
0.336 |
|
1993 |
Schmied M, Breitschopf H, Gold R, Zischler H, Rothe G, Wekerle H, Lassmann H. Apoptosis of T lymphocytes in experimental autoimmune encephalomyelitis. Evidence for programmed cell death as a mechanism to control inflammation in the brain. The American Journal of Pathology. 143: 446-52. PMID 8342595 |
0.407 |
|
1993 |
Wekerle H. Experimental autoimmune encephalomyelitis as a model of immune-mediated CNS disease. Current Opinion in Neurobiology. 3: 779-84. PMID 8260829 DOI: 10.1016/0959-4388(93)90153-P |
0.34 |
|
1993 |
Linington C, Berger T, Perry L, Weerth S, Hinze-Selch D, Zhang Y, Lu HC, Lassmann H, Wekerle H. T cells specific for the myelin oligodendrocyte glycoprotein mediate an unusual autoimmune inflammatory response in the central nervous system. European Journal of Immunology. 23: 1364-72. PMID 7684687 DOI: 10.1002/eji.1830230627 |
0.43 |
|
1993 |
Salvetti M, Ristori G, D'Amato M, Buttinelli C, Falcone M, Fieschi C, Wekerle H, Pozzilli C. Predominant and stable T cell responses to regions of myelin basic protein can be detected in individual patients with multiple sclerosis. European Journal of Immunology. 23: 1232-9. PMID 7684682 DOI: 10.1002/eji.1830230606 |
0.34 |
|
1993 |
Melms A, Weissert R, Klinkert WE, Schalke BC, Tzartos S, Wekerle H. Specific immune complexes augment in vitro acetylcholine receptor-specific T-cell proliferation. Neurology. 43: 583-8. PMID 7680803 |
0.338 |
|
1993 |
Saruhan-Direskeneli G, Weber F, Meinl E, Pette M, Giegerich G, Hinkkanen A, Epplen JT, Hohlfeld R, Wekerle H. Human T cell autoimmunity against myelin basic protein: CD4+ cells recognizing epitopes of the T cell receptor beta chain from a myelin basic protein-specific T cell clone. European Journal of Immunology. 23: 530-6. PMID 7679649 DOI: 10.1002/eji.1830230235 |
0.385 |
|
1993 |
Hinkkanen AE, Määttä J, Qin YF, Linington C, Salmi A, Wekerle H. Novel Tcr Tcra-V and -J transcripts expressed in rat myelin-specific T-cell lines. Immunogenetics. 37: 235-8. PMID 7678406 DOI: 10.1007/BF00191892 |
0.336 |
|
1993 |
Kiefer R, Gold R, Gehrmann J, Lindholm D, Wekerle H, Kreutzberg GW. Transforming growth factor beta expression in reactive spinal cord microglia and meningeal inflammatory cells during experimental allergic neuritis. Journal of Neuroscience Research. 36: 391-8. PMID 7505838 DOI: 10.1002/Jnr.490360405 |
0.492 |
|
1993 |
Meinl E, Weber F, Drexler K, Morelle C, Ott M, Saruhan-Direskeneli G, Goebels N, Ertl B, Jechart G, Giegerich G, Schönbeck S, Bannwarth W, Wekerle H, Hohlfeld R. Myelin basic protein-specific T lymphocyte repertoire in multiple sclerosis: Complexity of the response and dominance of nested epitopes due to recruitment of multiple T cell clones Journal of Clinical Investigation. 92: 2633-2643. PMID 7504690 |
0.349 |
|
1993 |
Weber F, Meinl E, Drexler K, Czlonkowska A, Huber S, Fickenscher H, Müller-Fleckenstein I, Fleckenstein B, Wekerle H, Hohlfeld R. Transformation of human T-cell clones by Herpesvirus saimiri: intact antigen recognition by autonomously growing myelin basic protein-specific T cells. Proceedings of the National Academy of Sciences of the United States of America. 90: 11049-53. PMID 7504291 |
0.409 |
|
1992 |
Gehrmann J, Gold R, Linington C, Lannes-Vieira J, Wekerle H, Kreutzberg GW. Spinal cord microglia in experimental allergic neuritis. Evidence for fast and remote activation. Laboratory Investigation; a Journal of Technical Methods and Pathology. 67: 100-13. PMID 1625441 |
0.581 |
|
1992 |
Halachmi E, Ben-Nun A, Lehmann D, Karussis D, Wekerle H, Berke G. Delineation of tissue damage mechanisms in experimental autoimmune encephalomyelitis (EAE). I. Cell detachment and lysis induced by encephalitogenic CD4+ T lymphocytes. Journal of Autoimmunity. 5: 411-25. PMID 1384527 DOI: 10.1016/0896-8411(92)90002-8 |
0.402 |
|
1992 |
Yamamura T, Sun D, Aloisi F, Klinkert WE, Wekerle H. Interaction between oligodendroglia and immune cells: mitogenic effect of an oligodendrocyte precursor cell line on syngeneic T lymphocytes. Journal of Neuroscience Research. 32: 178-89. PMID 1383559 DOI: 10.1002/jnr.490320207 |
0.373 |
|
1992 |
Giegerich G, Pette M, Meinl E, Epplen JT, Wekerle H, Hinkkanen A. Diversity of T cell receptor alpha and beta chain genes expressed by human T cells specific for similar myelin basic protein peptide/major histocompatibility complexes. European Journal of Immunology. 22: 753-8. PMID 1372258 DOI: 10.1002/eji.1830220319 |
0.329 |
|
1992 |
Giegerich G, Pette M, Meinl E, Epplen JT, Wekerle H, Hinkanen A. Diversity of T cell receptor alpha and beta chain genes expressed by human T cells specific for similar myelin basic protein/major histocompatibility complexes. European Journal of Immunology. 22: 1331. PMID 1349534 DOI: 10.1002/eji.1830220533 |
0.366 |
|
1992 |
Wekerle H. Myelin specific, autoaggressive T cell clones in the normal immune repertoire: their nature and their regulation. International Reviews of Immunology. 9: 231-41. PMID 1285063 |
0.366 |
|
1991 |
Sun D, Wekerle H, Raper K, Gold DP. CD4-CD8- splenic T cells from Lewis rats recovered from experimental autoimmune encephalomyelitis respond to encephalitogenic T cells that mediate this disorder. Cellular Immunology. 137: 292-302. PMID 1909933 DOI: 10.1016/0008-8749(91)90080-U |
0.312 |
|
1991 |
Wekerle H. Immunopathogenesis of multiple sclerosis. Acta Neurologica. 13: 197-204. PMID 1891986 |
0.409 |
|
1991 |
Wekerle H, Engelhardt B, Risau W, Meyermann R. Interaction of T lymphocytes with cerebral endothelial cells in vitro. Brain Pathology (Zurich, Switzerland). 1: 107-14. PMID 1727014 DOI: 10.1111/J.1750-3639.1991.Tb00647.X |
0.313 |
|
1991 |
Weber F, Meinl E, Aloisi F, Borsellino G, Hohlfeld R, Wekerle H. Antigen-dependent HLA-DR-restricted lysis of human astrocytes by CD4+ T-cell lines specific for myelin-basic protein (MBP) Journal of Neuroimmunology. 35: 125. DOI: 10.1016/0165-5728(91)91072-K |
0.324 |
|
1991 |
Saruhan G, Pette M, Giegerich G, Hinkkanen A, Epplen JT, Hohlfeld R, Wekerle H. T cell receptor immunotherapy in multiple sclerosis? Human T cell lines recognizing peptide analogs of T cell receptor β chains from MBP specific autologous T cell clones Journal of Neuroimmunology. 35: 30. DOI: 10.1016/0165-5728(91)90886-C |
0.368 |
|
1991 |
Kramer R, Zhang Y, Tontsch U, Thoenen H, Wekerle H. A murine T cell line expressing and secreting biologically active nerve growth factor Journal of Neuroimmunology. 35: 23. DOI: 10.1016/0165-5728(91)90872-5 |
0.301 |
|
1990 |
Adorini L, Barnaba V, Bona C, Celada F, Lanzavecchia A, Sercarz E, Suciu-Foca N, Wekerle H. New perspectives on immunointervention in autoimmune diseases. Immunology Today. 11: 383-6. PMID 2078289 DOI: 10.1016/0167-5699(90)90148-3 |
0.303 |
|
1990 |
Pette M, Fujita K, Wilkinson D, Altmann DM, Trowsdale J, Giegerich G, Hinkkanen A, Epplen JT, Kappos L, Wekerle H. Myelin autoreactivity in multiple sclerosis: recognition of myelin basic protein in the context of HLA-DR2 products by T lymphocytes of multiple-sclerosis patients and healthy donors. Proceedings of the National Academy of Sciences of the United States of America. 87: 7968-72. PMID 1700423 |
0.361 |
|
1990 |
Risau W, Engelhardt B, Wekerle H. Immune function of the blood-brain barrier: incomplete presentation of protein (auto-)antigens by rat brain microvascular endothelium in vitro. The Journal of Cell Biology. 110: 1757-66. PMID 1692329 DOI: 10.1083/Jcb.110.5.1757 |
0.399 |
|
1990 |
Umehara F, Qin YF, Goto M, Wekerle H, Meyermann R. Experimental autoimmune encephalomyelitis in the maturing central nervous system. Transfer of myelin basic protein-specific T line lymphocytes to neonatal Lewis rats. Laboratory Investigation; a Journal of Technical Methods and Pathology. 62: 147-55. PMID 1689408 |
0.328 |
|
1990 |
Zhang YP, Porter S, Wekerle H. Schwann cells and myasthenia gravis. Preferential uptake of soluble and membrane-bound AChR by normal and immortalized Schwann cells, and immunogenic presentation to AChR-specific T line lymphocytes. The American Journal of Pathology. 136: 111-22. PMID 1688688 |
0.33 |
|
1989 |
Chluba J, Steeg C, Becker A, Wekerle H, Epplen JT. T cell receptor beta chain usage in myelin basic protein-specific rat T lymphocytes. European Journal of Immunology. 19: 279-84. PMID 2467813 DOI: 10.1002/eji.1830190210 |
0.376 |
|
1989 |
Melms A, Chrestel S, Schalke BC, Wekerle H, Mauron A, Ballivet M, Barkas T. Autoimmune T lymphocytes in myasthenia gravis. Determination of target epitopes using T lines and recombinant products of the mouse nicotinic acetylcholine receptor gene. The Journal of Clinical Investigation. 83: 785-90. PMID 2466050 DOI: 10.1172/Jci113958 |
0.315 |
|
1988 |
Sun D, Qin Y, Chluba J, Epplen JT, Wekerle H. Suppression of experimentally induced autoimmune encephalomyelitis by cytolytic T-T cell interactions. Nature. 332: 843-5. PMID 2965794 DOI: 10.1038/332843a0 |
0.344 |
|
1988 |
Sun D, Ben-Nun A, Wekerle H. Regulatory circuits in autoimmunity: recruitment of counter-regulatory CD8+ T cells by encephalitogenic CD4+ T line cells. European Journal of Immunology. 18: 1993-9. PMID 2905995 DOI: 10.1002/Eji.1830181219 |
0.377 |
|
1988 |
Sun D, Meyermann R, Wekerle H. Cytotoxic T cells in autoimmune disease of the central nervous system. Annals of the New York Academy of Sciences. 532: 221-9. PMID 2460009 |
0.4 |
|
1987 |
Zhang Y, Tzartos S, Schalke BC, Melms A, Wekerle H. Interaction between AChR-specific T- and B-line lymphocytes: antigen presentation by B hybridoma cells and the enhancing effect of monoclonal antibodies on T-cell activation. Annals of the New York Academy of Sciences. 505: 71-81. PMID 3500671 |
0.342 |
|
1987 |
Wekerle H, Sun D, Oropeza-Wekerle RL, Meyermann R. Immune reactivity in the nervous system: modulation of T-lymphocyte activation by glial cells. The Journal of Experimental Biology. 132: 43-57. PMID 3323405 |
0.376 |
|
1987 |
Melms A, Kirchner T, Barkas T, Tzartos S, Schalke B, Müller-Hermelink H, Wekerle H. Intrathymic pathogenesis of myasthenia gravis: AChR specific T ylmphocytes and AChR expression in the myasthenic thymus Journal of Neuroimmunology. 16: 122-123. DOI: 10.1016/0165-5728(87)90317-1 |
0.3 |
|
1986 |
Vass K, Lassmann H, Wekerle H, Wisniewski HM. The distribution of Ia antigen in the lesions of rat acute experimental allergic encephalomyelitis. Acta Neuropathologica. 70: 149-60. PMID 3488634 DOI: 10.1007/Bf00691433 |
0.39 |
|
1986 |
Linington C, Wekerle H, Meyermann R. T lymphocyte autoimmunity in peripheral nervous system autoimmune disease. Agents and Actions. 19: 256-65. PMID 2435116 |
0.344 |
|
1986 |
Wekerle H, Schwab M, Linington C, Meyermann R. Antigen presentation in the peripheral nervous system: Schwann cells present endogenous myelin autoantigens to lymphocytes. European Journal of Immunology. 16: 1551-7. PMID 2434335 DOI: 10.1002/eji.1830161214 |
0.418 |
|
1986 |
Linington C, Mann A, Izumo S, Uyemura K, Suzuki M, Meyermann R, Wekerle H. Induction of experimental allergic neuritis in the BN rat: P2 protein-specific T cells overcome resistance to actively induced disease. Journal of Immunology (Baltimore, Md. : 1950). 137: 3826-31. PMID 2431045 |
0.408 |
|
1986 |
Sun D, Wekerle H. Ia-restricted encephalitogenic T lymphocytes mediating EAE lyse autoantigen-presenting astrocytes. Nature. 320: 70-2. PMID 2419764 DOI: 10.1038/320070a0 |
0.362 |
|
1986 |
Heininger K, Stoll G, Linington C, Toyka KV, Wekerle H. Conduction failure and nerve conduction slowing in experimental allergic neuritis induced by P2-specific T-cell lines. Annals of Neurology. 19: 44-9. PMID 2418761 DOI: 10.1002/Ana.410190109 |
0.311 |
|
1986 |
WEKERLE H, DIAMANTSTEIN T. Suppression of T-Cell Mediated Autoimmune Disease with Antibodies against the Interleukin-2 Receptor Effect of Hybridoma ART-18 on T Line Mediated Experimental Autoimmune Encephalomyelitis Annals of the New York Academy of Sciences. 475: 401-403. DOI: 10.1111/j.1749-6632.1986.tb20907.x |
0.375 |
|
1986 |
SUN D, WEKERLE H. Interaction between autoaggressive T Lymphocyte Lines and Their Target Tissues Encephalitogenic T Lymphocytes Destroy Astrocytes Presenting Myelin Basic Protein Annals of the New York Academy of Sciences. 475: 399-400. DOI: 10.1111/J.1749-6632.1986.TB20906.X |
0.316 |
|
1985 |
Fierz W, Endler B, Reske K, Wekerle H, Fontana A. Astrocytes as antigen-presenting cells. I. Induction of Ia antigen expression on astrocytes by T cells via immune interferon and its effect on antigen presentation. Journal of Immunology (Baltimore, Md. : 1950). 134: 3785-93. PMID 3921611 |
0.358 |
|
1985 |
Wekerle H, Fierz W. T cell approach to demyelinating diseases. Springer Seminars in Immunopathology. 8: 97-110. PMID 3890239 |
0.353 |
|
1985 |
Schalke BC, Klinkert WE, Wekerle H, Dwyer DS. Enhanced activation of a T cell line specific for acetylcholine receptor (AChR) by using anti-AChR monoclonal antibodies plus receptors. Journal of Immunology (Baltimore, Md. : 1950). 134: 3643-8. PMID 2580892 |
0.39 |
|
1985 |
Wekerle H, Fierz W. T lymphocyte autoimmunity in experimental autoimmune encephalomyelitis. Concepts in Immunopathology. 2: 102-27. PMID 2439202 |
0.336 |
|
1985 |
Schluesener HJ, Wekerle H. Autoaggressive T lymphocyte lines recognizing the encephalitogenic region of myelin basic protein: in vitro selection from unprimed rat T lymphocyte populations. Journal of Immunology (Baltimore, Md. : 1950). 135: 3128-33. PMID 2413113 |
0.314 |
|
1985 |
Izumo S, Linington C, Wekerle H, Meyermann R. Morphologic study on experimental allergic neuritis mediated by T cell line specific for bovine P2 protein in Lewis rats. Laboratory Investigation; a Journal of Technical Methods and Pathology. 53: 209-18. PMID 2410663 |
0.36 |
|
1985 |
HUSBANDS S, LININGTON C, WEKERLE H. Lewis rat T-cell lines specific for human myelin basic protein Biochemical Society Transactions. 13: 905-906. DOI: 10.1042/BST0130905 |
0.329 |
|
1984 |
Wekerle H, Fierz W. T lymphocyte lines in the study of autoimmune disease. Blut. 49: 187-94. PMID 6206905 |
0.305 |
|
1984 |
Linington C, Izumo S, Suzuki M, Uyemura K, Meyermann R, Wekerle H. A permanent rat T cell line that mediates experimental allergic neuritis in the Lewis rat in vivo. Journal of Immunology (Baltimore, Md. : 1950). 133: 1946-50. PMID 6206142 |
0.346 |
|
1984 |
Wekerle H. T cell autoimmunity to brain myelin. Survey of Immunologic Research. 3: 221-4. PMID 6201988 |
0.346 |
|
1984 |
Wekerle H. Immunospecific therapy of central nervous system autoaggression with an antigen-specific T cell line. Progress in Clinical and Biological Research. 146: 435-41. PMID 6201913 |
0.332 |
|
1984 |
Fontana A, Fierz W, Wekerle H. Astrocytes present myelin basic protein to encephalitogenic T-cell lines. Nature. 307: 273-6. PMID 6198590 |
0.352 |
|
1983 |
Wekerle H. T cell autoimmunity 1982. Experimental autoimmune encephalomyelitis. Survey of Immunologic Research. 2: 296-8. PMID 6201983 |
0.399 |
|
1982 |
Hohlfeld R, Kalies I, Ernst M, Ketelsen UP, Wekerle H. T-lymphocytes in experimental autoimmune myasthenia gravis. Isolation of T-helper cell lines. Journal of the Neurological Sciences. 57: 265-80. PMID 6186772 |
0.35 |
|
1981 |
Wekerle H, Hohlfeld R, Ketelsen UP, Kalden JR, Kalies I. Thymic myogenesis, T-lymphocytes and the pathogenesis of myasthenia gravis. Annals of the New York Academy of Sciences. 377: 455-76. PMID 6978664 |
0.316 |
|
1981 |
Ben-Nun A, Wekerle H, Cohen IR. Vaccination against autoimmune encephalomyelitis with T-lymphocyte line cells reactive against myelin basic protein. Nature. 292: 60-1. PMID 6974307 DOI: 10.1038/292060A0 |
0.366 |
|
1981 |
Ben-Nun A, Wekerle H, Cohen IR. The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis. European Journal of Immunology. 11: 195-9. PMID 6165588 DOI: 10.1002/Eji.1830110307 |
0.361 |
|
1976 |
Wekerle H. Rat anti-lymphocyte alloantibodies block con A-stimulation of T lymphocytes: inhibition of a polyclonally specific T cell reaction. Advances in Experimental Medicine and Biology. 66: 403-8. PMID 1083646 |
0.343 |
|
1975 |
Waksal SD, Cohen IR, Waksal HW, Wekerle H, St Pierre RL, Feldman M. Induction of T-cells differentiation in vitro by thymus epithelial cells. Annals of the New York Academy of Sciences. 249: 492-8. PMID 236721 DOI: 10.1111/J.1749-6632.1975.Tb29098.X |
0.385 |
|
1974 |
Wekerle H, Kölsch E, Feldman M. T cell recognition of cell-surface antigens. II. Antigen recognition is necessary yet not sufficient for triggering T cell-mediated immunity. European Journal of Immunology. 4: 246-50. PMID 4212381 DOI: 10.1002/Eji.1830040404 |
0.307 |
|
1974 |
Wekerle H, Feldman M. T cell recognition of cell surface antigens. I. Specificity. European Journal of Immunology. 4: 240-6. PMID 4137229 DOI: 10.1002/Eji.1830040403 |
0.331 |
|
1973 |
Wekerle H, Cohen IR, Feldman M. Thymus reticulum cell cultures confer T cell properties on spleen cells from thymus-deprived animals. European Journal of Immunology. 3: 745-8. PMID 4544457 DOI: 10.1002/Eji.1830031202 |
0.368 |
|
1972 |
Cohen IR, Wekerle H. Autosensitization of lymphocytes against thymus reticulum cells. Science (New York, N.Y.). 176: 1324-5. PMID 5034542 DOI: 10.1126/science.176.4041.1324 |
0.32 |
|
1972 |
Wekerle H, Lonai P, Feldman M. Fractionation of antigen reactive cells on a cellular immunoadsorbent: factors determining recognition of antigens by T-lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 69: 1620-4. PMID 4504379 |
0.326 |
|
1972 |
Lonai P, Wekerle H, Feldman M. Fractionation of specific antigen-reactive cells in an in vitro system of cell-mediated immunity. Nature: New Biology. 235: 235-6. PMID 4502411 DOI: 10.1038/Newbio235235A0 |
0.319 |
|
1972 |
Feldman M, Cohen IR, Wekerle H. T-cell mediated immunity in vitro: an analysis of antigen recognition and target cell lysis. Transplantation Reviews. 12: 57-90. PMID 4119632 DOI: 10.1111/J.1600-065X.1972.Tb00053.X |
0.357 |
|
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