| Year |
Citation |
Score |
| 2011 |
Vong AM, Daneshjou N, Norori PY, Sheng H, Braciak TA, Sercarz EE, Gabaglia CR. Spectratyping analysis of the islet-reactive T cell repertoire in diabetic NOD Igμ(null) mice after polyclonal B cell reconstitution. Journal of Translational Medicine. 9: 101. PMID 21722394 DOI: 10.1186/1479-5876-9-101 |
0.343 |
|
| 2011 |
Rasche SS, Phillips M, McInerney MF, Sercarz EE, Quinn A. IL-13Rα1 expression on β-cell-specific T cells in NOD mice. Diabetes. 60: 1716-25. PMID 21617187 DOI: 10.2337/Db10-1229 |
0.444 |
|
| 2010 |
Gabaglia CR, DeLaney A, Gee J, Halder R, Graham FL, Gauldie J, Sercarz EE, Braciak TA. Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice Journal of Translational Medicine. 8. PMID 20946663 DOI: 10.1186/1479-5876-8-98 |
0.337 |
|
| 2010 |
Maverakis E, Menezes JS, Ametani A, Han M, Stevens DB, He Y, Wang Y, Ono Y, Miyamura Y, Lam KS, Ward ES, Sercarz EE. Molecular mimics can induce a nonautoaggressive repertoire that preempts induction of autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 107: 2550-5. PMID 20133742 DOI: 10.1073/Pnas.0914508107 |
0.52 |
|
| 2009 |
Dai YD, Sercarz EE. Antigen processing patterns determine GAD65-specific regulation vs. pathogenesis. Frontiers in Bioscience (Landmark Edition). 14: 344-51. PMID 19273071 DOI: 10.2741/3248 |
0.519 |
|
| 2009 |
Jensen KD, Sercarz EE, Gabaglia CR. Altered peptide ligands can modify the Th2 T cell response to the immunodominant 161-175 peptide of LACK (Leishmania homolog for the receptor of activated C kinase). Molecular Immunology. 46: 366-74. PMID 19042022 DOI: 10.1016/J.Molimm.2008.10.024 |
0.498 |
|
| 2009 |
Dai YD, Marrero IG, Gros P, Zaghouani H, Wicker LS, Sercarz EE. Slc11a1 enhances the autoimmune diabetogenic T-cell response by altering processing and presentation of pancreatic islet antigens. Diabetes. 58: 156-64. PMID 18984740 DOI: 10.2337/Db07-1608 |
0.485 |
|
| 2009 |
Dai Y, Marrero I, Li Y, Wilson D, Haskins K, Sercarz E. OR.89. C-terminus of GAD65 is Capable of Inducing Diabetic Effector T Cells After Processing and Presentation of Apoptotic Islet Beta Cells in NOD Mice Clinical Immunology. 131: S37. DOI: 10.1016/J.Clim.2009.03.104 |
0.407 |
|
| 2008 |
Penitente R, Nicolò C, Van den Elzen P, Di Sante G, Agrati C, Aloisi F, Sercarz EE, Ria F. Administration of PLP139-151 primes T cells distinct from those spontaneously responsive in vitro to this antigen. Journal of Immunology (Baltimore, Md. : 1950). 180: 6611-22. PMID 18453580 DOI: 10.4049/Jimmunol.180.10.6611 |
0.511 |
|
| 2008 |
Dai YD, Jensen KP, Marrero I, Li N, Quinn A, Sercarz EE. N-terminal flanking residues of a diabetes-associated GAD65 determinant are necessary for activation of antigen-specific T cells in diabetes-resistant mice. European Journal of Immunology. 38: 968-76. PMID 18395850 DOI: 10.1002/Eji.200737703 |
0.467 |
|
| 2008 |
Maverakis E, Beech JT, Schneider S, Sercarz EE. Presentation of a determinant by MHC class II can be prevented through competitive capture by a flanking determinant on a multideterminant peptide. Journal of Autoimmunity. 31: 59-65. PMID 18375101 DOI: 10.1016/J.Jaut.2008.02.004 |
0.438 |
|
| 2008 |
Madakamutil LT, Maricic I, Sercarz EE, Kumar V. Immunodominance in the TCR repertoire of a [corrected] TCR peptide-specific CD4+ Treg population that controls experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 180: 4577-85. PMID 18354180 DOI: 10.4049/Jimmunol.180.7.4577 |
0.363 |
|
| 2008 |
Burton AR, Vincent E, Arnold PY, Lennon GP, Smeltzer M, Li CS, Haskins K, Hutton J, Tisch RM, Sercarz EE, Santamaria P, Workman CJ, Vignali DA. On the pathogenicity of autoantigen-specific T-cell receptors. Diabetes. 57: 1321-30. PMID 18299317 DOI: 10.2337/Db07-1129 |
0.453 |
|
| 2008 |
Sercarz E, Raja-Gabaglia C. Etiology of autoimmune disease: how T cells escape self-tolerance. Methods in Molecular Biology (Clifton, N.J.). 380: 271-83. PMID 17876099 |
0.427 |
|
| 2007 |
Menezes JS, van den Elzen P, Thornes J, Huffman D, Droin NM, Maverakis E, Sercarz EE. A public T cell clonotype within a heterogeneous autoreactive repertoire is dominant in driving EAE. The Journal of Clinical Investigation. 117: 2176-85. PMID 17627303 DOI: 10.1172/Jci28277 |
0.395 |
|
| 2007 |
Wucherpfennig KW, Allen PM, Celada F, Cohen IR, De Boer R, Garcia KC, Goldstein B, Greenspan R, Hafler D, Hodgkin P, Huseby ES, Krakauer DC, Nemazee D, Perelson AS, Pinilla C, ... ... Sercarz EE, et al. Polyspecificity of T cell and B cell receptor recognition. Seminars in Immunology. 19: 216-24. PMID 17398114 DOI: 10.1016/J.Smim.2007.02.012 |
0.422 |
|
| 2007 |
Raja Gabaglia C, Diaz de Durana Y, Graham FL, Gauldie J, Sercarz EE, Braciak TA. Attenuation of the glucocorticoid response during Ad5IL-12 adenovirus vector treatment enhances natural killer cell-mediated killing of MHC class I-negative LNCaP prostate tumors. Cancer Research. 67: 2290-7. PMID 17332360 DOI: 10.1158/0008-5472.Can-06-3399 |
0.373 |
|
| 2007 |
Marrero I, Dai Y, Sercarz E. Tracking Putative Pathogenic Members of the T Cell Repertoire in NOD Mice Clinical Immunology. 123: S26. DOI: 10.1016/J.Clim.2007.03.243 |
0.431 |
|
| 2007 |
Dai Y, Shirdel B, Chau S, Wicker L, Gros P, Sercarz E. Nramp1 Enhances Autoimmune Diabetogenic T Cell Response by Altering the Processing and Presentation of Pancreatic Islet Antigens in Dendritic Cells Clinical Immunology. 123: S25-S26. DOI: 10.1016/J.Clim.2007.03.241 |
0.488 |
|
| 2006 |
Marrero I, Huffman D, Kalil J, Sercarz EE, Coelho V. TAP1-/- mice present oligoclonal BV-BJ expansions following the rejection of grafts bearing self antigens. Immunology. 118: 461-71. PMID 16895555 DOI: 10.1111/J.1365-2567.2006.02387.X |
0.487 |
|
| 2006 |
Quinn A, McInerney M, Huffman D, McInerney B, Mayo S, Haskins K, Sercarz E. T cells to a dominant epitope of GAD65 express a public CDR3 motif. International Immunology. 18: 967-79. PMID 16641112 DOI: 10.1093/Intimm/Dxl033 |
0.497 |
|
| 2006 |
Dai YD, Carayanniotis G, Sercarz E. Antigen processing by autoreactive B cells promotes determinant spreading. Cellular & Molecular Immunology. 2: 169-75. PMID 16212883 |
0.439 |
|
| 2006 |
Maverakis E, Moudgil KD, Sercarz EE. Generation of T-Cell Antigenic Determinants in Autoimmunity and Their Recognition The Autoimmune Diseases. 179-191. DOI: 10.1016/B978-012595961-2/50017-2 |
0.432 |
|
| 2005 |
Dai YD, Jensen KP, Lehuen A, Masteller EL, Bluestone JA, Wilson DB, Sercarz EE. A peptide of glutamic acid decarboxylase 65 can recruit and expand a diabetogenic T cell clone, BDC2.5, in the pancreas. Journal of Immunology (Baltimore, Md. : 1950). 175: 3621-7. PMID 16148106 DOI: 10.4049/Jimmunol.175.6.3621 |
0.522 |
|
| 2005 |
Kumar V, Sercarz E. Feedback regulation of autoimmunity via TCR-centered regulation. International Reviews of Immunology. 24: 199-209. PMID 16036374 DOI: 10.1080/08830180590934967 |
0.487 |
|
| 2005 |
Moudgil KD, Sercarz EE. Understanding crypticity is the key to revealing the pathogenesis of autoimmunity. Trends in Immunology. 26: 355-9. PMID 15922666 DOI: 10.1016/J.It.2005.05.007 |
0.506 |
|
| 2005 |
Giannoni F, Barnett J, Bi K, Samodal R, Lanza P, Marchese P, Billetta R, Vita R, Klein MR, Prakken B, Kwok WW, Sercarz E, Altman A, Albani S. Clustering of T cell ligands on artificial APC membranes influences T cell activation and protein kinase C theta translocation to the T cell plasma membrane. Journal of Immunology (Baltimore, Md. : 1950). 174: 3204-11. PMID 15749850 DOI: 10.4049/Jimmunol.174.6.3204 |
0.445 |
|
| 2005 |
Sun W, Nie H, Li N, Zang YC, Zhang D, Feng G, Ni L, Xu R, Prasad S, Robinson RR, Ho W, Sercarz E, Zhang JZ. Skewed T-cell receptor BV14 and BV16 expression and shared CDR3 sequence and common sequence motifs in synovial T cells of rheumatoid arthritis. Genes and Immunity. 6: 248-61. PMID 15674392 DOI: 10.1038/Sj.Gene.6364166 |
0.405 |
|
| 2004 |
van den Elzen P, Menezes JS, Ametani A, Maverakis E, Madakamutil L, Tang XL, Kumar V, Sercarz EE. Limited clonality in autoimmunity: drivers and regulators. Autoimmunity Reviews. 3: 524-9. PMID 15546801 DOI: 10.1016/J.Autrev.2004.07.008 |
0.489 |
|
| 2004 |
Gabaglia CR, Sercarz EE, Diaz-De-Durana Y, Hitt M, Graham FL, Gauldie J, Braciak TA. Life-long systemic protection in mice vaccinated with L. major and adenovirus IL-12 vector requires active infection, macrophages and intact lymph nodes. Vaccine. 23: 247-57. PMID 15531044 DOI: 10.1016/J.Vaccine.2004.05.012 |
0.344 |
|
| 2004 |
Sinha P, Chi HH, Kim HR, Clausen BE, Pederson B, Sercarz EE, Forster I, Moudgil KD. Mouse lysozyme-M knockout mice reveal how the self-determinant hierarchy shapes the T cell repertoire against this circulating self antigen in wild-type mice. Journal of Immunology (Baltimore, Md. : 1950). 173: 1763-71. PMID 15265906 DOI: 10.4049/Jimmunol.173.3.1763 |
0.392 |
|
| 2004 |
Honda A, Ametani A, Matsumoto T, Iwaya A, Kano H, Hachimura S, Ohkawa K, Kaminogawa S, Suzuki K, Sercarz EE, Kumar V. Vaccination with an immunodominant peptide of bovine type II collagen induces an anti-TCR response, and modulates the onset and severity of collagen-induced arthritis. International Immunology. 16: 737-45. PMID 15096482 DOI: 10.1093/Intimm/Dxh075 |
0.479 |
|
| 2004 |
Sercarz EE, Maverakis E. Recognition and function in a degenerate immune system. Molecular Immunology. 40: 1003-8. PMID 15036903 DOI: 10.1016/J.Molimm.2003.11.002 |
0.322 |
|
| 2004 |
Ria F, Gallard A, Gabaglia CR, Guéry JC, Sercarz EE, Adorini L. Selection of similar naive T cell repertoires but induction of distinct T cell responses by native and modified antigen. Journal of Immunology (Baltimore, Md. : 1950). 172: 3447-53. PMID 15004144 DOI: 10.4049/Jimmunol.172.6.3447 |
0.494 |
|
| 2004 |
Im JS, Quinn A, Sercarz EE, Lake DF. Molecular profile of the T cell receptors of regulatory and effector CD4+ T cells recognizing overlapping determinants on glutamic acid decarboxylase (524-543). Molecular Immunology. 40: 971-80. PMID 14725793 DOI: 10.1016/J.Molimm.2003.09.007 |
0.458 |
|
| 2004 |
Melo ME, Stevens DB, Sercarz EE, Gabaglia CR. Nasal instillation of gpMBP can exacerbate murine EAE: effect of mucosal priming is an age-dependent phenomenon. Journal of Autoimmunity. 22: 13-20. PMID 14709409 DOI: 10.1016/J.Jaut.2003.09.005 |
0.377 |
|
| 2004 |
Sercarz E, Maverakis E, van den Elzen P, Madakamutil L, Kumar V. Seven surprises in the TCR-centred regulation of immune responsiveness in an autoimmune system. Novartis Foundation Symposium. 252: 165-71; discussion 1. PMID 14609218 DOI: 10.1002/0470871628.Ch12 |
0.477 |
|
| 2003 |
Elewaut D, Lawton AP, Nagarajan NA, Maverakis E, Khurana A, Honing S, Benedict CA, Sercarz E, Bakke O, Kronenberg M, Prigozy TI. The adaptor protein AP-3 is required for CD1d-mediated antigen presentation of glycosphingolipids and development of Valpha14i NKT cells. The Journal of Experimental Medicine. 198: 1133-46. PMID 14557411 DOI: 10.1084/Jem.20030143 |
0.428 |
|
| 2003 |
Sercarz EE, Maverakis E. Mhc-guided processing: binding of large antigen fragments. Nature Reviews. Immunology. 3: 621-9. PMID 12974477 DOI: 10.1038/Nri1149 |
0.329 |
|
| 2003 |
Sercarz EE. Arraying autoimmunity treatment. Nature Biotechnology. 21: 1017-9. PMID 12949565 DOI: 10.1038/Nbt0903-1017 |
0.35 |
|
| 2003 |
Sercarz EE. Large antigens such as GAD-65 become involved in pathogenic self-reactivity, but fortunately only rarely. Journal of Autoimmunity. 20: 203-6. PMID 12753804 DOI: 10.1016/S0896-8411(03)00029-5 |
0.34 |
|
| 2003 |
Rubin B, Durana YDd, Li N, Sercarz EE. Regulator T Cells: Specific for Antigen and/or Antigen Receptors? Scandinavian Journal of Immunology. 57: 399-409. PMID 12753496 DOI: 10.1046/J.1365-3083.2003.01249.X |
0.525 |
|
| 2003 |
Maverakis E, Beech J, Stevens DB, Ametani A, Brossay L, van den Elzen P, Mendoza R, Thai Q, Macias LH, Ethell D, Campagnoni CW, Campagnoni AT, Sette A, Sercarz EE. Autoreactive T cells can be protected from tolerance induction through competition by flanking determinants for access to class II MHC. Proceedings of the National Academy of Sciences of the United States of America. 100: 5342-7. PMID 12707414 DOI: 10.1073/Pnas.0936151100 |
0.441 |
|
| 2003 |
Madakamutil LT, Maricic I, Sercarz E, Kumar V. Regulatory T cells control autoimmunity in vivo by inducing apoptotic depletion of activated pathogenic lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 170: 2985-92. PMID 12626551 DOI: 10.4049/Jimmunol.170.6.2985 |
0.485 |
|
| 2003 |
Braciak TA, Pedersen B, Chin J, Hsiao C, Ward ES, Maricic I, Jahng A, Graham FL, Gauldie J, Sercarz EE, Kumar V. Protection against experimental autoimmune encephalomyelitis generated by a recombinant adenovirus vector expressing the V beta 8.2 TCR is disrupted by coadministration with vectors expressing either IL-4 or -10. Journal of Immunology (Baltimore, Md. : 1950). 170: 765-74. PMID 12517939 DOI: 10.4049/Jimmunol.170.2.765 |
0.402 |
|
| 2003 |
Sercarz EE, Maverakis E. Erratum: MHC-guided processing: binding of large antigen fragments Nature Reviews Immunology. 3: 1-1. DOI: 10.1038/Nri1206 |
0.314 |
|
| 2002 |
Melo ME, Gabaglia CR, Moudgil KD, Sercarz EE, Quinn A. Strain-dependent effect of nasal instillation of antigen on the immune response in mice. The Israel Medical Association Journal : Imaj. 4: 902-7. PMID 12455176 |
0.348 |
|
| 2002 |
Stevens DB, Gold DP, Sercarz EE, Moudgil KD. The Wistar Kyoto (RT1(l)) rat is resistant to myelin basic protein-induced experimental autoimmune encephalomyelitis: comparison with the susceptible Lewis (RT1(l)) strain with regard to the MBP-directed CD4+ T cell repertoire and its regulation. Journal of Neuroimmunology. 126: 25-36. PMID 12020954 DOI: 10.1016/S0165-5728(02)00045-0 |
0.367 |
|
| 2002 |
Sercarz EE. Processing creates the self. Nature Immunology. 3: 110-2. PMID 11812983 DOI: 10.1038/Ni0202-110 |
0.455 |
|
| 2002 |
Kumar V, Sercarz E. An integrative model of regulation centered on recognition of TCR peptide/MHC complexes. Immunological Reviews. 182: 113-21. PMID 11722628 DOI: 10.1034/J.1600-065X.2001.1820109.X |
0.479 |
|
| 2002 |
Quinn A, Melo M, Ethell D, Sercarz EE. Relative resistance to nasally induced tolerance in non-obese diabetic mice but not other I-A(g7)-expressing mouse strains. International Immunology. 13: 1321-33. PMID 11581177 DOI: 10.1093/Intimm/13.10.1321 |
0.419 |
|
| 2001 |
Kaufman DL, Tisch R, Sarvetnick N, Chatenoud L, Harrison LC, Haskins K, Quinn A, Sercarz E, Singh B, Von Herrath M, Wegmann D, Wen L, Zekzer D. Report from the 1st International NOD Mouse T-Cell Workshop and the Follow-Up Mini-Workshop Diabetes. 50: 2459-2463. PMID 11679422 DOI: 10.2337/Diabetes.50.11.2459 |
0.482 |
|
| 2001 |
Quinn A, McInerney MF, Sercarz EE. MHC class I-restricted determinants on the glutamic acid decarboxylase 65 molecule induce spontaneous CTL activity. Journal of Immunology (Baltimore, Md. : 1950). 167: 1748-57. PMID 11466400 DOI: 10.4049/Jimmunol.167.3.1748 |
0.456 |
|
| 2001 |
Kumar V, Maglione J, Thatte J, Pederson B, Sercarz E, Ward ES. Induction of a type 1 regulatory CD4 T cell response following V beta 8.2 DNA vaccination results in immune deviation and protection from experimental autoimmune encephalomyelitis. International Immunology. 13: 835-41. PMID 11369712 DOI: 10.1093/Intimm/13.6.835 |
0.406 |
|
| 2001 |
Maverakis E, van den Elzen P, Sercarz EE. Self-reactive T cells and degeneracy of T cell recognition: evolving concepts-from sequence homology to shape mimicry and TCR flexibility. Journal of Autoimmunity. 16: 201-9. PMID 11334484 DOI: 10.1006/Jaut.2000.0493 |
0.457 |
|
| 2001 |
Moudgil KD, Kim E, Yun OJ, Chi HH, Brahn E, Sercarz EE. Environmental modulation of autoimmune arthritis involves the spontaneous microbial induction of T cell responses to regulatory determinants within heat shock protein 65 Journal of Immunology. 166: 4237-4243. PMID 11238677 DOI: 10.4049/Jimmunol.166.6.4237 |
0.329 |
|
| 2001 |
Quinn A, McInerney B, Reich EP, Kim O, Jensen KP, Sercarz EE. Regulatory and effector CD4 T cells in nonobese diabetic mice recognize overlapping determinants on glutamic acid decarboxylase and use distinct V beta genes. Journal of Immunology (Baltimore, Md. : 1950). 166: 2982-91. PMID 11207247 DOI: 10.4049/Jimmunol.166.5.2982 |
0.484 |
|
| 2000 |
Maverakis E, Mendoza R, Southwood S, Raja-Gabaglia C, Abromson-Leeman S, Campagnoni AT, Sette A, Sercarz EE. Immunogenicity of self antigens is unrelated to MHC-binding affinity: T-cell determinant structure of Golli-MBP in the BALB/c mouse. Journal of Autoimmunity. 15: 315-22. PMID 11040072 DOI: 10.1006/Jaut.2000.0436 |
0.501 |
|
| 2000 |
Schneider SC, Ohmen J, Fosdick L, Gladstone B, Guo J, Ametani A, Sercarz EE, Deng H. Cutting edge: introduction of an endopeptidase cleavage motif into a determinant flanking region of hen egg lysozyme results in enhanced T cell determinant display. Journal of Immunology (Baltimore, Md. : 1950). 165: 20-3. PMID 10861030 DOI: 10.4049/Jimmunol.165.1.20 |
0.392 |
|
| 2000 |
Wilson SS, van den Elzen P, Maverakis E, Beech JT, Braciak TA, Kumar V, Sercarz EE. Residual public repertoires to self. Journal of Neuroimmunology. 107: 233-9. PMID 10854662 DOI: 10.1016/S0165-5728(00)00218-6 |
0.505 |
|
| 2000 |
Maverakis E, Beech JT, Wilson SS, Quinn A, Pedersen B, Sercarz EE. T cell receptor complementarity determining region 3 length analysis reveals the absence of a characteristic public T cell repertoire in neonatal tolerance. The response in the "tolerant" mouse within the residual repertoire is quantitatively similar but qualitatively different. The Journal of Experimental Medicine. 191: 695-702. PMID 10684861 DOI: 10.1084/Jem.191.4.695 |
0.511 |
|
| 2000 |
Kang HK, Mikszta JA, Deng H, Sercarz EE, Jensen PE, Kim BS. Processing and reactivity of T cell epitopes containing two cysteine residues from hen egg-white lysozyme (HEL74-90). Journal of Immunology (Baltimore, Md. : 1950). 164: 1775-82. PMID 10657624 DOI: 10.4049/Jimmunol.164.4.1775 |
0.489 |
|
| 1999 |
Kumar V, Sercarz E. Distinct levels of regulation in organ-specific autoimmune diseases. Life Sciences. 65: 1523-30. PMID 10574217 DOI: 10.1016/S0024-3205(99)00198-8 |
0.458 |
|
| 1998 |
Drakesmith H, O'Neil D, Schneider SC, Binks M, Medd P, Sercarz E, Beverley P, Chain B. In vivo priming of T cells against cryptic determinants by dendritic cells exposed to interleukin 6 and native antigen Proceedings of the National Academy of Sciences of the United States of America. 95: 14903-14908. PMID 9843988 DOI: 10.1073/Pnas.95.25.14903 |
0.445 |
|
| 1998 |
Sercarz EE. Immune focusing vs diversification and their connection to immune regulation. Immunological Reviews. 164: 5-10. PMID 9795758 DOI: 10.1111/J.1600-065X.1998.Tb01202.X |
0.301 |
|
| 1998 |
Schneider SC, Deng HK, Rottinger B, Sharma S, Stolina M, Bonpane C, Miller A, Dubinett S, Kyewski B, Sercarz E. Tolerance and determinant hierarchy. Novartis Foundation Symposium. 215: 54-66; discussion 66. PMID 9760571 DOI: 10.1002/9780470515525.Ch5 |
0.521 |
|
| 1998 |
Moudgil KD, Sercarz EE, Grewal IS. Modulation of the immunogenecity of antigenic determinants by their flanking residues Immunology Today. 19: 217-220. PMID 9613039 DOI: 10.1016/S0167-5699(97)01233-4 |
0.491 |
|
| 1998 |
Grewal IS, Miller A, Sercarz EE. The influence of mouse housing density on autoimmune reactivity. Autoimmunity. 26: 209-14. PMID 9543181 DOI: 10.3109/08916939709008026 |
0.317 |
|
| 1998 |
Maverakis E, Bhardwaj V, Kumar V, Sette A, Camagnoni A, Sercarz E. Degeneracy of specificity of T cells recognizing the amino terminus of myelin basic protein (MBP) Journal of Neuroimmunology. 90: 7. DOI: 10.1016/S0165-5728(98)91237-1 |
0.428 |
|
| 1997 |
Schneider SC, Sercarz EE. Antigen processing differences among APC. Human Immunology. 54: 148-58. PMID 9297533 DOI: 10.1016/S0198-8859(97)00079-7 |
0.437 |
|
| 1997 |
Kumar V, Aziz F, Sercarz E, Miller A. Regulatory T cells specific for the same framework 3 region of the Vbeta8.2 chain are involved in the control of collagen II-induced arthritis and experimental autoimmune encephalomyelitis. The Journal of Experimental Medicine. 185: 1725-33. PMID 9151697 DOI: 10.1084/Jem.185.10.1725 |
0.516 |
|
| 1997 |
Grewal IS, Heilig M, Miller A, Sercarz EE. Environmental regulation of T-cell function in mice: group housing of males affects accessory cell function. Immunology. 90: 165-8. PMID 9135542 DOI: 10.1046/J.1365-2567.1997.00190.X |
0.371 |
|
| 1997 |
Moudgil KD, Chang TT, Eradat H, Chen AM, Gupta RS, Brahn E, Sercarz EE. Diversification of T cell responses to carboxy-terminal determinants within the 65-kD heat-shock protein is involved in regulation of autoimmune arthritis Journal of Experimental Medicine. 185: 1307-1316. PMID 9104817 DOI: 10.1084/Jem.185.7.1307 |
0.401 |
|
| 1997 |
Schoenberger SP, Sercarz EE. Harnessing self-reactivity in cancer immunotherapy. Seminars in Immunology. 8: 303-9. PMID 8956459 DOI: 10.1006/Smim.1996.0039 |
0.46 |
|
| 1997 |
Kumar V, Sercarz E. Dysregulation of potentially pathogenic self reactivity is crucial for the manifestation of clinical autoimmunity. Journal of Neuroscience Research. 45: 334-9. PMID 8872893 DOI: 10.1002/(Sici)1097-4547(19960815)45:4<334::Aid-Jnr2>3.0.Co;2-A |
0.474 |
|
| 1997 |
Moudgil K, Chang T, Eradat H, Chen A, Chi H, Sachdev S, Canceko J, Kim E, Gupta R, Brahn E, Sercarz E. Diversification of T cell responses to C-terminal determinants within hsp65 is involved in regulation of autoimmune arthritis Immunology Letters. 56: 381. DOI: 10.1016/S0165-2478(97)86537-6 |
0.434 |
|
| 1996 |
Nanda NK, Sercarz E. A truncated T cell receptor repertoire reveals underlying immunogenicity of an antigenic determinant Journal of Experimental Medicine. 184: 1037-1043. PMID 9064321 DOI: 10.1084/Jem.184.3.1037 |
0.506 |
|
| 1996 |
Kumar V, Stellrecht K, Sercarz E. Inactivation of T cell receptor peptide-specific CD4 regulatory T cells induces chronic experimental autoimmune encephalomyelitis (EAE). The Journal of Experimental Medicine. 184: 1609-17. PMID 8920851 DOI: 10.1084/Jem.184.5.1609 |
0.523 |
|
| 1996 |
Quinn A, Sercarz EE. T cells with multiple fine specificities are used by non-obese diabetic (NOB) mice in the response to GAD(524-543) Journal of Autoimmunity. 9: 365-370. PMID 8816972 DOI: 10.1006/Jaut.1996.0049 |
0.456 |
|
| 1996 |
Moudgil KD, Deng H, Nanda NK, Grewal Iqbal S. IS, Ametani A, Sercarz EE. Antigen processing and T cell repertoires as crucial aleatory features in induction of autoimmunity Journal of Autoimmunity. 9: 227-234. PMID 8738967 DOI: 10.1006/Jaut.1996.0028 |
0.484 |
|
| 1996 |
Singh RR, Hahn BH, Sercarz EE. Neonatal peptide exposure can prime T cells and, upon subsequent immunization, induce their immune deviation: Implications for antibody vs. T cell-mediated autoimmunity Journal of Experimental Medicine. 183: 1613-1621. PMID 8666919 DOI: 10.1084/Jem.183.4.1613 |
0.477 |
|
| 1996 |
Moudgil KD, Grewal IS, Jensen PE, Sercarz EE. Unresponsiveness to a self-peptide of mouse lysozyme owing to hindrance of T cell receptor-major histocompatibility complex/peptide interaction caused by flanking epitopic residues. The Journal of Experimental Medicine. 183: 535-46. PMID 8627165 DOI: 10.1084/Jem.183.2.535 |
0.422 |
|
| 1996 |
Melo ME, Goldschmidt TJ, Bhardwaj V, Ho L, Miller A, Sercarz E. Immune deviation during the induction of tolerance by way of nasal installation: nasal installation itself can induce Th-2 responses and exacerbation of disease. Annals of the New York Academy of Sciences. 778: 408-11. PMID 8611005 DOI: 10.1111/J.1749-6632.1996.Tb21158.X |
0.32 |
|
| 1995 |
Ram Raj Singh, Ebling FM, Sercarz EE, Hahn BH. Immune tolerance to autoantibody-derived peptides delays development of autoimmunity in murine lupus Journal of Clinical Investigation. 96: 2990-2996. PMID 8675671 DOI: 10.1172/Jci118371 |
0.518 |
|
| 1995 |
Nanda NK, Sercarz EE. The positively selected T cell repertoire: Is it exclusively restricted to the selecting MHC? International Immunology. 7: 353-358. PMID 7794817 DOI: 10.1093/Intimm/7.3.353 |
0.424 |
|
| 1995 |
Nanda NK, Arzoo KK, Geysen HM, Sette A, Sercarz EE. Recognition of multiple peptide cores by a single T cell receptor. The Journal of Experimental Medicine. 182: 531-9. PMID 7629510 DOI: 10.1084/Jem.182.2.531 |
0.423 |
|
| 1995 |
Nanda NK, Sercarz EE. Induction of anti-self-immunity to cure cancer Cell. 82: 13-17. PMID 7606778 DOI: 10.1016/0092-8674(95)90047-0 |
0.306 |
|
| 1995 |
Kumar V, Bhardwaj V, Soares L, Alexander J, Sette A, Sercarz E. Major histocompatibility complex binding affinity of an antigenic determinant is crucial for the differential secretion of interleukin 4/5 or interferon gamma by T cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 9510-4. PMID 7568164 DOI: 10.1073/PNAS.92.21.9510 |
0.321 |
|
| 1995 |
Singh RR, Kumar V, Ebling FM, Southwood S, Sette A, Sercarz EE, Hahn BH. T cell determinants from autoantibodies to DNA can upregulate autoimmunity in murine systemic lupus erythematosus. The Journal of Experimental Medicine. 181: 2017-27. PMID 7539036 DOI: 10.1084/Jem.181.6.2017 |
0.453 |
|
| 1995 |
Grewal IS, Moudgil KD, Sercarz EE. Hindrance of binding to class II major histocompatibility complex molecules by a single amino acid residue contiguous to a determinant leads to crypticity of the determinant as well as lack of response to the protein antigen Proceedings of the National Academy of Sciences of the United States of America. 92: 1779-1783. PMID 7533299 DOI: 10.1073/Pnas.92.5.1779 |
0.409 |
|
| 1995 |
Vogel LA, Sercarz EE, Metzger DW. Antibody response of murine B1 cells to hen eggwhite lysozyme. Cellular Immunology. 161: 88-97. PMID 7532551 DOI: 10.1006/Cimm.1995.1012 |
0.484 |
|
| 1994 |
Manca F, Dessi V, Shastri N, Oki A, Kaplan M, Clarke J, Miller A, Sercarz EE. Isolation of lysozyme-specific T cell clones that discriminate between native and denatured antigen Cellular Immunology. 154: 420-429. PMID 8131210 DOI: 10.1006/Cimm.1994.1088 |
0.467 |
|
| 1994 |
Gammon G, Edger D, McBride WH, Sercarz EE. Complications in the functional analysis of transfected MHC genes. Cellular Immunology. 154: 219-30. PMID 8118888 DOI: 10.1006/Cimm.1994.1070 |
0.468 |
|
| 1994 |
Moudgil KD, Sercarz EE. The T cell repertoire against cryptic self determinants and its involvement in autoimmunity and cancer Clinical Immunology and Immunopathology. 73: 283-289. PMID 7955556 DOI: 10.1006/Clin.1994.1200 |
0.493 |
|
| 1994 |
Moudgil KD, Sercarz EE. Can antitumor immune responses discriminate between self and nonself? Immunology Today. 15: 353-355. PMID 7916947 DOI: 10.1016/0167-5699(94)90172-4 |
0.332 |
|
| 1994 |
Nanda NK, Sercarz EE, Hsu DH, Kronenberg M. A unique pattern of lymphokine synthesis is a characteristic of certain antigen-specific suppressor T cell clones. International Immunology. 6: 731-7. PMID 7802868 DOI: 10.1093/Intimm/6.5.731 |
0.427 |
|
| 1994 |
Soares LR, Sercarz EE, Miller A. Vaccination of the Leishmania major susceptible BALB/c mouse. I. The precise selection of peptide determinant influences CD4+ T cell subset expression. International Immunology. 6: 785-94. PMID 7521670 DOI: 10.1093/Intimm/6.5.785 |
0.404 |
|
| 1994 |
Benichou G, Fedoseyeva E, Olson CA, Geysen HM, McMillan M, Sercarz EE. Disruption of the determinant hierarchy on a self-MHC peptide: concomitant tolerance induction to the dominant determinant and priming to the cryptic self-determinant. International Immunology. 6: 131-8. PMID 7511927 DOI: 10.1093/intimm/6.1.131 |
0.41 |
|
| 1993 |
Heilig M, Irwin M, Grewal I, Sercarz E. Sympathetic regulation of T-helper cell function. Brain, Behavior, and Immunity. 7: 154-63. PMID 8394164 DOI: 10.1006/brbi.1993.1017 |
0.325 |
|
| 1993 |
Moudgil KD, Ametani A, Grewal IS, Kumar V, Sercarz EE. Processing of self-proteins and its impact on shaping the t cell repertoire, autoimmunity and immune regulation International Reviews of Immunology. 10: 365-377. PMID 8294849 DOI: 10.3109/08830189309061711 |
0.449 |
|
| 1993 |
Moudgil KD, Sercarz EE. Dominant determinants in hen eggwhite lysozyme correspond to the cryptic determinants within its self-homologue, mouse lysozyme: Implications in shaping of the T cell repertoire and autoimmunity Journal of Experimental Medicine. 178: 2131-2138. PMID 8245785 DOI: 10.1084/Jem.178.6.2131 |
0.477 |
|
| 1993 |
Deng H, Fosdick L, Sercarz E. The involvement of antigen processing in determinant selection by class II MHC and its relationship to immunodominance. Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. 101: 655-62. PMID 8240783 DOI: 10.1111/J.1699-0463.1993.Tb00161.X |
0.41 |
|
| 1993 |
Deng H, Apple R, Clare-Salzler M, Trembleau S, Mathis D, Adorini L, Sercarz E. Determinant capture as a possible mechanism of protection afforded by major histocompatibility complex class II molecules in autoimmune disease. The Journal of Experimental Medicine. 178: 1675-80. PMID 8228814 DOI: 10.1084/Jem.178.5.1675 |
0.346 |
|
| 1993 |
Kaufman DL, Clare-Salzler M, Tian J, Forsthuber T, Ting GS, Robinson P, Atkinson MA, Sercarz EE, Tobin AJ, Lehmann PV. Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes. Nature. 366: 69-72. PMID 7694152 DOI: 10.1038/366069A0 |
0.484 |
|
| 1993 |
Kumar V, Sercarz EE. The involvement of T cell receptor peptide-specific regulatory CD4+ T cells in recovery from antigen-induced autoimmune disease. The Journal of Experimental Medicine. 178: 909-16. PMID 7688792 DOI: 10.1084/Jem.178.3.909 |
0.53 |
|
| 1993 |
Lehmann PV, Sercarz EE, Forsthuber T, Dayan CM, Gammon G. Determinant spreading and the dynamics of the autoimmune T-cell repertoire. Immunology Today. 14: 203-8. PMID 7686009 DOI: 10.1016/0167-5699(93)90163-F |
0.414 |
|
| 1993 |
Jelonek MT, Brust JL, Song CH, Calandra GB, Miller A, Sercarz EE, Keller MA. Maternal HEL immunization has no lasting effects on the immune response of offspring to immunization with hen egg-white lysozyme. Cellular Immunology. 148: 422-34. PMID 7684330 DOI: 10.1006/Cimm.1993.1123 |
0.384 |
|
| 1993 |
Kumar V, Sercarz E. T cell regulatory circuitry: antigen-specific and TCR-idiopeptide-specific T cell interactions in EAE. International Reviews of Immunology. 9: 287-97. PMID 7683710 DOI: 10.3109/08830189309051212 |
0.479 |
|
| 1993 |
Sercarz EE, Lehmann PV, Ametani A, Benichou G, Miller A, Moudgil K. Dominance and crypticity of T cell antigenic determinants. Annual Review of Immunology. 11: 729-66. PMID 7682817 DOI: 10.1146/Annurev.Iy.11.040193.003501 |
0.424 |
|
| 1993 |
Ebling FM, Tsao BP, Singh RR, Sercarz E, Hahn BH. A peptide derived from an autoantibody can stimulate T cells in the (NZB x NZW)F1 mouse model of systemic lupus erythematosus Arthritis and Rheumatism. 36: 355-364. PMID 7680861 DOI: 10.1002/Art.1780360311 |
0.459 |
|
| 1993 |
Sercarz E. The Processing and Presentation of Self Antigens International Reviews of Immunology. 10: i-ii. DOI: 10.3109/08830189309061703 |
0.329 |
|
| 1993 |
Kumar V, Sercarz E. Presentation of TCR-idiopeptides in the priming of CD4+, class II-restricted regulatory T cells in EAE Journal of Neuroimmunology. 43: 219. DOI: 10.1016/0165-5728(93)90149-S |
0.398 |
|
| 1993 |
Lehmann PV, Forsthuber T, Miller A, Sercarz EE. T cell responses to cryptic determinants of myelin basic protein are revealed after immunization with a dominant peptide of the molecule Journal of Neuroimmunology. 43: 209. DOI: 10.1016/0165-5728(93)90116-G |
0.468 |
|
| 1992 |
Kumar V, Sercarz EE. Regulation of autoimmunity. Current Opinion in Immunology. 3: 888-95. PMID 1793531 DOI: 10.1016/S0952-7915(05)80009-3 |
0.425 |
|
| 1992 |
Benichou G, Takizawa PA, Olson CA, McMillan M, Sercarz EE. Donor major histocompatibility complex (MHC) peptides are presented by recipient MHC molecules during graft rejection. The Journal of Experimental Medicine. 175: 305-8. PMID 1730925 DOI: 10.1084/Jem.175.1.305 |
0.451 |
|
| 1992 |
Bhardwaj V, Kumar V, Geysen HM, Sercarz EE. Subjugation of dominant immunogenic determinants within a chimeric peptide. European Journal of Immunology. 22: 2009-16. PMID 1379183 DOI: 10.1002/Eji.1830220809 |
0.431 |
|
| 1992 |
Lehmann PV, Forsthuber T, Miller A, Sercarz EE. Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen. Nature. 358: 155-7. PMID 1377368 DOI: 10.1038/358155A0 |
0.535 |
|
| 1992 |
Nanda NK, Arzoo KK, Sercarz EE. In a small multideterminant peptide, each determinant is recognized by a different V beta gene segment. The Journal of Experimental Medicine. 176: 297-302. PMID 1377226 DOI: 10.1084/Jem.176.1.297 |
0.391 |
|
| 1992 |
Cibotti R, Kanellopoulos JM, Cabaniols JP, Halle-Panenko O, Kosmatopoulos K, Sercarz E, Kourilsky P. Tolerance to a self-protein involves its immunodominant but does not involve its subdominant determinants. Proceedings of the National Academy of Sciences of the United States of America. 89: 416-20. PMID 1370355 DOI: 10.1073/Pnas.89.1.416 |
0.444 |
|
| 1991 |
Hsu DH, Sercarz EE, Miller A. Internal connectivity is pervasive among primary and secondary anti-hen egg white lysozyme (HEL) IgG monoclonal antibodies. International Immunology. 1: 197-204. PMID 2487684 DOI: 10.1093/Intimm/1.2.197 |
0.364 |
|
| 1991 |
Song CH, Calandra GB, Miller A, Sercarz EE, Keller MA. Evidence for idiotypic sharing between conventional and naturally activated B cells. European Journal of Immunology. 21: 2005-10. PMID 1889454 DOI: 10.1002/Eji.1830210906 |
0.428 |
|
| 1991 |
Keller MA, Palmer CJ, Jelonek MT, Song CH, Miller A, Sercarz EE, Calandra GB, Brust JL. Modulation of the immune response by maternal antibody. Advances in Experimental Medicine and Biology. 310: 207-13. PMID 1809000 DOI: 10.1007/978-1-4615-3838-7_27 |
0.38 |
|
| 1991 |
Jiang H, Sercarz E, Nitecki D, Pernis B. The problems of presentation of T cell receptor peptides by activated T cells. Annals of the New York Academy of Sciences. 636: 28-32. PMID 1793215 DOI: 10.1111/J.1749-6632.1991.Tb33435.X |
0.451 |
|
| 1991 |
Nanda NK, Apple R, Sercarz E. Limitations in plasticity of the T-cell receptor repertoire. Proceedings of the National Academy of Sciences of the United States of America. 88: 9503-7. PMID 1719532 DOI: 10.1073/Pnas.88.21.9503 |
0.426 |
|
| 1991 |
Benichou G, Sercarz E. The presentation of self-peptides: tolerance and competition. International Reviews of Immunology. 6: 75-88. PMID 1715376 DOI: 10.3109/08830189009056619 |
0.452 |
|
| 1991 |
Gammon G, Sercarz EE, Benichou G. The dominant self and the cryptic self: shaping the autoreactive T-cell repertoire. Immunology Today. 12: 193-5. PMID 1715167 DOI: 10.1016/0167-5699(91)90052-U |
0.437 |
|
| 1991 |
Sercarz E, Krzych U. The distinctive specificity of antigen-specific suppressor T cells. Immunology Today. 12: 111-8. PMID 1711854 DOI: 10.1016/0167-5699(91)90094-A |
0.513 |
|
| 1991 |
Gammon G, Geysen HM, Apple RJ, Pickett E, Palmer M, Ametani A, Sercarz EE. T cell determinant structure: cores and determinant envelopes in three mouse major histocompatibility complex haplotypes. The Journal of Experimental Medicine. 173: 609-17. PMID 1705279 DOI: 10.1084/Jem.173.3.609 |
0.518 |
|
| 1990 |
Gammon G, Sercarz E. Does the presence of self-reactive T cells indicate the breakdown of tolerance? Clinical Immunology and Immunopathology. 56: 287-97. PMID 2143967 DOI: 10.1016/0090-1229(90)90150-O |
0.495 |
|
| 1990 |
Adorini L, Barnaba V, Bona C, Celada F, Lanzavecchia A, Sercarz E, Suciu-Foca N, Wekerle H. New perspectives on immunointervention in autoimmune diseases. Immunology Today. 11: 383-6. PMID 2078289 DOI: 10.1016/0167-5699(90)90148-3 |
0.406 |
|
| 1990 |
Song CH, Calandra GB, Palmer CJ, Miller A, Sercarz EE, Keller MA. Inhibition of offspring response to HEL-CFA by administration of anti-HEL MAB to the mother is not related to the predominant idiotype, IdXE, or specificity of the MAB. Cellular Immunology. 131: 311-24. PMID 1700739 DOI: 10.1016/0008-8749(90)90257-R |
0.367 |
|
| 1990 |
Benichou G, Takizawa PA, Ho PT, Killion CC, Olson CA, McMillan M, Sercarz EE. Immunogenicity and tolerogenicity of self-major histocompatibility complex peptides. The Journal of Experimental Medicine. 172: 1341-6. PMID 1700053 DOI: 10.1084/Jem.172.5.1341 |
0.467 |
|
| 1989 |
Keller MA, Kaplan MA, Kenyon NS, Miller A, Sercarz EE. Primary response to lysozyme (HEL) and HEL-LPS in neonatal A/J mice: presence of characteristic adult pattern of regulatory idiotype and fine specificity restriction. Cellular Immunology. 119: 143-52. PMID 2646024 DOI: 10.1016/0008-8749(89)90230-X |
0.387 |
|
| 1989 |
Gammon G, Sercarz E. How some T cells escape tolerance induction. Nature. 342: 183-5. PMID 2478888 DOI: 10.1038/342183A0 |
0.545 |
|
| 1989 |
Ando DG, Clayton J, Kono D, Urban JL, Sercarz EE. Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype. Cellular Immunology. 124: 132-43. PMID 2478300 DOI: 10.1016/0008-8749(89)90117-2 |
0.517 |
|
| 1989 |
Krzych U, Nanda N, Sercarz E. Specificity and interactions of CD8+ T suppressor cells Research in Immunology. 140: 302-307. PMID 2474185 DOI: 10.1016/0923-2494(89)90067-9 |
0.39 |
|
| 1989 |
Shivakumar S, Sercarz EE, Krzych U. The molecular context of determinants within the priming antigen establishes a hierarchy of T cell induction: T cell specificities induced by peptides of beta-galactosidase vs. the whole antigen. European Journal of Immunology. 19: 681-7. PMID 2471649 DOI: 10.1002/Eji.1830190417 |
0.543 |
|
| 1989 |
Clayton JP, Gammon GM, Ando DG, Kono DH, Hood L, Sercarz EE. Peptide-specific prevention of experimental allergic encephalomyelitis. Neonatal tolerance induced to the dominant T cell determinant of myelin basic protein. The Journal of Experimental Medicine. 169: 1681-91. PMID 2469764 DOI: 10.1084/Jem.169.5.1681 |
0.523 |
|
| 1989 |
Sercarz EE. The Architectonics of Immune Dominance: The Aleatory Effects of Molecular Position on the Choice of Antigenic Determinants Chemical Immunology. 46: 169-185. DOI: 10.1159/000318832 |
0.37 |
|
| 1988 |
Krzych U, Fowler AV, Miller A, Sercarz EE. Induction of helper and suppressor T cells by nonoverlapping determinants on the large protein antigen, beta-galactosidase. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 2: 141-5. PMID 2963778 DOI: 10.1096/Fasebj.2.2.2963778 |
0.538 |
|
| 1988 |
Kaplan MA, Keller MA, Hsu DH, Ch'ng LK, Miller A, Sercarz EE. A predominant idiotype independent of specificity, or Ig and H-2 allotypes, is found in the primary but not the secondary murine antibody response to lysozyme. European Journal of Immunology. 18: 1567-74. PMID 2461307 DOI: 10.1002/Eji.1830181015 |
0.416 |
|
| 1988 |
Urban JL, Kumar V, Kono DH, Gomez C, Horvath SJ, Clayton J, Ando DG, Sercarz EE, Hood L. Restricted use of T cell receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy. Cell. 54: 577-92. PMID 2456857 DOI: 10.1016/0092-8674(88)90079-7 |
0.386 |
|
| 1988 |
Celada F, Sercarz EE. Preferential pairing of T-B specificities in the same antigen: the concept of directional help. Vaccine. 6: 94-8. PMID 2455389 DOI: 10.1016/S0264-410X(88)80006-9 |
0.45 |
|
| 1987 |
Kawahara DJ, Miller A, Sercarz EE. The induction of helper and suppressor cells with secondary anti-hen egg-white lysozyme B hybridoma cells in the absence of antigen. European Journal of Immunology. 17: 1101-8. PMID 2957214 DOI: 10.1002/Eji.1830170805 |
0.505 |
|
| 1987 |
Gammon G, Shastri N, Cogswell J, Wilbur S, Sadegh-Nasseri S, Krzych U, Miller A, Sercarz E. The choice of T-cell epitopes utilized on a protein antigen depends on multiple factors distant from, as well as at the determinant site Immunological Reviews. 98: 53-73. PMID 2443442 DOI: 10.1111/J.1600-065X.1987.Tb00519.X |
0.71 |
|
| 1986 |
Sadegh-Nasseri S, Dessi V, Sercarz EE. Selective reversal of H-2-linked genetic unresponsiveness to lysozymes. II. Alteration in the T helper/T suppressor balance, owing to gene(s) linked to Ir-2, leads to responsiveness in BALB.B. European Journal of Immunology. 16: 486-92. PMID 2938974 DOI: 10.1002/Eji.1830160504 |
0.417 |
|
| 1986 |
Shastri N, Gammon G, Miller A, Sercarz EE. Ia molecule-associated selectivity in T cell recognition of a 23-amino-acid peptide of lysozyme. The Journal of Experimental Medicine. 164: 882-96. PMID 2427637 DOI: 10.1084/Jem.164.3.882 |
0.349 |
|
| 1986 |
Gammon GM, Oki A, Shastri N, Sercarz EE. Induction of tolerance to one determinant on a synthetic peptide does not affect the response to a second linked determinant. Implications for the mechanism of neonatal tolerance induction. The Journal of Experimental Medicine. 164: 667-72. PMID 2425038 DOI: 10.1084/Jem.164.2.667 |
0.416 |
|
| 1986 |
Gammon G, Dunn K, Shastri N, Oki A, Wilbur S, Sercarz EE. Neonatal T-cell tolerance to minimal immunogenic peptides is caused by clonal inactivation. Nature. 319: 413-5. PMID 2418364 DOI: 10.1038/319413A0 |
0.534 |
|
| 1985 |
Oki A, Sercarz E. T cell tolerance studied at the level of antigenic determinants. I. Latent reactivity to lysozyme peptides that lack suppressogenic epitopes can be revealed in lysozyme-tolerant mice. The Journal of Experimental Medicine. 161: 897-911. PMID 2580937 DOI: 10.1084/Jem.161.5.897 |
0.557 |
|
| 1985 |
Manca F, Kunkl A, Fenoglio D, Fowler A, Sercarz E, Celada F. Constraints in T-B cooperation related to epitope topology on E. coli beta-galactosidase. I. The fine specificity of T cells dictates the fine specificity of antibodies directed to conformation-dependent determinants. European Journal of Immunology. 15: 345-50. PMID 2580713 DOI: 10.1002/Eji.1830150408 |
0.533 |
|
| 1985 |
Goverman J, Minard K, Shastri N, Hunkapiller T, Hansburg D, Sercarz E, Hood L. Rearranged beta T cell receptor genes in a helper T cell clone specific for lysozyme: no correlation between V beta and MHC restriction. Cell. 40: 859-67. PMID 2580639 DOI: 10.1016/0092-8674(85)90345-9 |
0.34 |
|
| 1985 |
Shastri N, Oki A, Miller A, Sercarz EE. Distinct recognition phenotypes exist for T cell clones specific for small peptide regions of proteins. Implications for the mechanisms underlying major histocompatibility complex-restricted antigen recognition and clonal deletion models of immune response gene defects. The Journal of Experimental Medicine. 162: 332-45. PMID 2409209 DOI: 10.1084/Jem.162.1.332 |
0.517 |
|
| 1985 |
Krzych U, Fowler AV, Sercarz EE. Repertoires of T cells directed against a large protein antigen, beta-galactosidase. II. Only certain T helper or T suppressor cells are relevant in particular regulatory interactions. The Journal of Experimental Medicine. 162: 311-23. PMID 2409208 DOI: 10.1084/Jem.162.1.311 |
0.51 |
|
| 1984 |
Metzger DW, Ch'ng LK, Miller A, Sercarz EE. The expressed lysozyme-specific B cell repertoire. I. Heterogeneity in the monoclonal anti-hen egg white lysozyme specificity repertoire, and its difference from the in situ repertoire. European Journal of Immunology. 14: 87-93. PMID 6607170 DOI: 10.1002/Eji.1830140116 |
0.414 |
|
| 1984 |
Sadegh-Nasseri S, Kipp DE, Taylor BA, Miller A, Sercarz E. Selective reversal of H-2 linked genetic unresponsiveness to lysozymes. I. Non-H-2 gene(s) closely linked to the Ir-2 locus on chromosome 2 permit(s) an antilysozyme response in H-2b mice. Immunogenetics. 20: 535-46. PMID 6437975 DOI: 10.1007/Bf00364356 |
0.622 |
|
| 1984 |
Wicker LS, Benjamin CD, Miller A, Sercarz EE. Immunodominant protein epitopes. II. The primary antibody response to hen egg white lysozyme requires and focuses upon a unique N-terminal epitope. European Journal of Immunology. 14: 447-53. PMID 6202529 DOI: 10.1002/Eji.1830140512 |
0.435 |
|
| 1984 |
Wicker LS, Katz M, Sercarz EE, Miller A. Immunodominant protein epitopes. I. Induction of suppression to hen egg white lysozyme is obliterated by removal of the first three N-terminal amino acids. European Journal of Immunology. 14: 442-7. PMID 6202528 DOI: 10.1002/Eji.1830140511 |
0.461 |
|
| 1982 |
Katz ME, Maizels RM, Wicker L, Miller A, Sercarz EE. Immunological focusing by th mouse major histocompatibility complex: mouse strains confronted with distantly related lysozymes confine their attention to very few epitopes. European Journal of Immunology. 12: 535-40. PMID 6180905 DOI: 10.1002/Eji.1830120702 |
0.492 |
|
| 1981 |
Krolick KA, Sercarz EE. Changing behavior of surface immunoglobulin on mouse B lymphocytes during immune development. II. Surface immunoglobulin modulation clearly distinguishes two stages of B-cell maturation in the neonate. Cellular Immunology. 65: 175-9. PMID 6976211 DOI: 10.1016/0008-8749(81)90062-9 |
0.367 |
|
| 1981 |
Krolick KA, Sercarz EE. Changing behavior of surface immunoglobulin on mouse B lymphocytes during immune development. I. LPS-induced changes in the lateral mobility of B lymphocyte surface immunoglobulins on two populations which express different surface immunoglobulin phenotypes. Cellular Immunology. 65: 166-74. PMID 6976210 DOI: 10.1016/0008-8749(81)90061-7 |
0.355 |
|
| 1981 |
Metzger DW, Furman A, Miller A, Sercarz EE. Idiotypic repertoire of anti-hen eggwhite lysozyme antibodies probed with hybridomas. Selection after immunization of an IdX marker common to antibodies of distinct epitope specificity. The Journal of Experimental Medicine. 154: 701-12. PMID 6168723 DOI: 10.1084/Jem.154.3.701 |
0.383 |
|
| 1981 |
Sercarz EE, Metzger DW. Epitope-specific and idiotype-specific cellular interactions in a model protein antigen system. Springer Seminars in Immunopathology. 3: 145-70. PMID 6168023 DOI: 10.1007/Bf02053974 |
0.36 |
|
| 1981 |
Araneo BA, Yowell RL, Metzger DW, Sercarz EE. Positive selection of major histocompatibility complex-restricted suppressor T cells bearing the predominant idiotype in the immune response to lysozyme. Proceedings of the National Academy of Sciences of the United States of America. 78: 499-503. PMID 6165994 DOI: 10.1073/Pnas.78.1.499 |
0.533 |
|
| 1980 |
Maizels RM, Clarke JA, Harvey MA, Miller A, Sercarz EE. Ir-gene control of T cell proliferative responses: two distinct expressions of the genetically nonresponsive state. European Journal of Immunology. 10: 516-20. PMID 6773781 DOI: 10.1002/Eji.1830100706 |
0.5 |
|
| 1980 |
Adorini L, Harvey MA, Rozycka-Jackson D, Miller A, Sercarz EE. Differential major histocompatibility complex-related activation of idiotypic suppressor T cells. Suppressor T cells cross-reactive to two distantly related lysozymes are not induced by one of them. The Journal of Experimental Medicine. 152: 521-31. PMID 6447750 DOI: 10.1084/Jem.152.3.521 |
0.514 |
|
| 1980 |
Metzger DW, Miller A, Sercarz EE. Sharing of an idiotypic marker by monoclonal antibodies specific for distinct regions of hen lysozyme. Nature. 287: 540-2. PMID 6158685 DOI: 10.1038/287540A0 |
0.424 |
|
| 1980 |
Maizels RM, Clarke JA, Harvey MA, Miller A, Sercarz EE. Epitope specificity of the T cell proliferative response to lysozyme: proliferative T cells react predominantly to different determinants from those recognized by B cells. European Journal of Immunology. 10: 509-15. PMID 6157540 DOI: 10.1002/Eji.1830100705 |
0.511 |
|
| 1980 |
Adorini L, Harvey M, Sercarz EE. The fine specificity of regulatory T cells. IV. Idiotypic complementarity and antigen-bridging interactions in the anti-lysozyme response. European Journal of Immunology. 9: 906-9. PMID 93548 DOI: 10.1002/Eji.1830091113 |
0.527 |
|
| 1979 |
Harvey MA, Adorini L, Miller A, Sercarz EE. Lysozyme-induced T-suppressor cells and antibodies have a predominant idiotype. Nature. 281: 594-6. PMID 91111 DOI: 10.1038/281594A0 |
0.523 |
|
| 1979 |
Adorini L, Harvey MA, Miller A, Sercarz EE. Fine specificity of regulatory T cells. II. Suppressor and helper T cells are induced by different regions of hen egg-white lysozyme in a genetically nonresponder mouse strain. The Journal of Experimental Medicine. 150: 293-306. PMID 88500 DOI: 10.1084/Jem.150.2.293 |
0.491 |
|
| 1979 |
Yowell RL, Araneo BA, Miller A, Sercarz EE. Amputation of a suppressor determinant on lysozyme reveals underlying T-cell reactivity to other determinants Nature. 279: 70-71. PMID 88016 DOI: 10.1038/279070A0 |
0.533 |
|
| 1978 |
Sercarz EE, Yowell RL, Turkin D, Miller A, Araneo BA, Adorini L. Different functional specificity repertoires for suppressor and helper T cells. Immunological Reviews. 39: 108-36. PMID 75167 DOI: 10.1111/J.1600-065X.1978.Tb00398.X |
0.47 |
|
| 1977 |
Turkin D, Sercarz EE. Key antigenic determinants in regulation of the immune response. Proceedings of the National Academy of Sciences of the United States of America. 74: 3984-7. PMID 71736 DOI: 10.1073/PNAS.74.9.3984 |
0.307 |
|
| 1976 |
Cecka JM, Stratton JA, Miller A, Sercarz E. Structural aspects of immune recognition of lysozymes. III. T cell specificity restriction and its consequences for antibody specificity European Journal of Immunology. 6: 639-646. PMID 1087241 DOI: 10.1002/Eji.1830060909 |
0.549 |
|
| 1975 |
DeLuca D, Miller A, Sercarz E. Antigen binding to lymphoid cells from unimmunized mice. IV. Shedding and reappearance of multiple antigen binding Ig receptors of T- and B-lymphocytes Cellular Immunology. 18: 286-303. PMID 1095215 DOI: 10.1016/0008-8749(75)90058-1 |
0.488 |
|
| 1975 |
DeLuca D, Miller A, Sercarz E. Antigen binding to lymphoid cells from unimmunized mice. III. Multiple antigen binding to single B- and T-cells Cellular Immunology. 18: 274-285. PMID 806358 DOI: 10.1016/0008-8749(75)90057-X |
0.464 |
|
| 1975 |
DeLuca D, Miller A, Sercarz E. Antigen binding to lymphoid cells from unimmunized mice. II. High frequency of antigen-binding cells for several protein antigens by a morphologically distinct Ig-bearing population of T- and B-lymphocytes Cellular Immunology. 18: 255-273. PMID 806357 DOI: 10.1016/0008-8749(75)90056-8 |
0.503 |
|
| 1975 |
Hill SW, Sercarz EE. Fine specificity of the H-2 linked immune response gene for the gallinaceous lysozymes. European Journal of Immunology. 5: 317-24. PMID 61870 DOI: 10.1002/Eji.1830050506 |
0.404 |
|
| 1975 |
Decker J, Sercarz E. Antigen binding cells and the generation of diversity Integrative and Comparative Biology. 15: 189-197. DOI: 10.1093/Icb/15.1.189 |
0.434 |
|
| 1974 |
Decker J, Clarke J, MacPherson L, Weinstein R, Sercarz EE. Early appearance of antigen-binding cells to two different antigens during fetal lymphoid development. Advances in Experimental Medicine and Biology. 29: 269-75. PMID 4546778 DOI: 10.1007/978-1-4615-9017-0_39 |
0.312 |
|
| 1974 |
Decker JM, Sercarz EE. Early simultaneous appearance of antigen binding cells in the foetal sheep. Nature. 252: 416-418. PMID 4473726 DOI: 10.1038/252416A0 |
0.409 |
|
| 1974 |
DeLuca D, Decker J, Miller A, Sercarz E. Antigen binding to lymphoid cells from unimmunized mice: High frequency of beta-galactosidase binding cells at optimal conditions Cellular Immunology. 10: 1-18. PMID 4218126 DOI: 10.1016/0008-8749(74)90146-4 |
0.394 |
|
| 1972 |
Bonavida B, Sercarz E. Structural basis for immune recognition of lysozymes. II. Reactive but non-immunogenic epitopes. European Journal of Immunology. 1: 166-70. PMID 4108347 DOI: 10.1002/Eji.1830010305 |
0.417 |
|
| 1971 |
Modabber F, Sercarz EE. Antigen binding and the immune response. II. The large number of antigen-binding cells in primed animals. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 135: 400-5. PMID 4921031 DOI: 10.3181/00379727-135-35061 |
0.45 |
|
| 1970 |
Byers VS, Sercarz EE. Induction and reversal of immune paralysis in vitro. The Journal of Experimental Medicine. 132: 845-57. PMID 5528413 DOI: 10.1084/JEM.132.5.845 |
0.323 |
|
| 1969 |
Byfield P, Sercarz E. The X-Y-Z scheme of immunocyte maturation. VII. Cell division and the establishment of short-term IgM memory. The Journal of Experimental Medicine. 129: 897-907. PMID 5305241 DOI: 10.1084/Jem.129.5.897 |
0.364 |
|
| 1968 |
Byers VS, Sercarz EE. The X-Y-Z scheme of immunocyte maturation. V. Paralysis of memory cells. The Journal of Experimental Medicine. 128: 715-28. PMID 5691983 DOI: 10.1084/Jem.128.4.715 |
0.378 |
|
| 1968 |
Sercarz EE, Modabber F. Antigen binding to cells: determination by enzymic fluorogenic group hydrolysis. Science (New York, N.Y.). 159: 884-5. PMID 5636329 DOI: 10.1126/Science.159.3817.884 |
0.37 |
|
| 1968 |
Byers VS, Sercarz EE. The X-Y-Z scheme of immunocyte maturation. IV. The exhaustion of memory cells. The Journal of Experimental Medicine. 127: 307-25. PMID 5635381 DOI: 10.1084/Jem.127.2.307 |
0.334 |
|
| 1968 |
Iványi J, Maler M, Wudl L, Sercarz E. High-dose delay of the immune response. Effect of actinomycin D on continuation of the immune response in vitro. The Journal of Experimental Medicine. 127: 1149-63. PMID 4172460 DOI: 10.1084/Jem.127.6.1149 |
0.354 |
|
| 1963 |
SERCARZ EE, COONS AH. THE ABSENCE OF ANTIBODY-PRODUCING CELLS DURING UNRESPONSIVENESS TO BSA IN THE MOUSE. Journal of Immunology (Baltimore, Md. : 1950). 90: 478-91. PMID 14051881 |
0.649 |
|
| 1959 |
SERCARZ E, COONS AH. Specific inhibition of antibody formation during immunological paralysis and unresponsiveness. Nature. 184: 1080-2. PMID 14444984 DOI: 10.1038/1841080a0 |
0.606 |
|
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