| Year |
Citation |
Score |
| 2023 |
Leighton GO, Shang S, Hageman S, Ginder GD, Williams DC. Analysis of the complex between MBD2 and the histone deacetylase core of NuRD reveals key interactions critical for gene silencing. Proceedings of the National Academy of Sciences of the United States of America. 120: e2307287120. PMID 37552759 DOI: 10.1073/pnas.2307287120 |
0.427 |
|
| 2023 |
Shang S, Li X, Azzo A, Truong T, Dozmorov M, Lyons C, Manna AK, Williams DC, Ginder GD. MBD2a-NuRD binds to the methylated γ-globin gene promoter and uniquely forms a complex required for silencing of HbF expression. Proceedings of the National Academy of Sciences of the United States of America. 120: e2302254120. PMID 37307480 DOI: 10.1073/pnas.2302254120 |
0.562 |
|
| 2019 |
Yu X, Azzo A, Bilinovich SM, Li X, Dozmorov M, Kurita R, Nakamura Y, Williams DC, Ginder GD. Disruption of the MBD2-NuRD complex but not MBD3-NuRD induces high level HbF expression in human erythroid cells. Haematologica. PMID 31004025 DOI: 10.3324/Haematol.2018.210963 |
0.486 |
|
| 2018 |
Ginder GD, Williams DC. Corrigendum to "Readers of DNA methylation, the MBD family as potential therapeutic targets" [Pharmacology & Therapeutics 184 (1) (2018) 98-111]. Pharmacology & Therapeutics. 190: 237-238. PMID 30268235 DOI: 10.1016/J.Pharmthera.2018.09.006 |
0.364 |
|
| 2018 |
Kovilakath A, Mohamad S, Hermes F, Wang SZ, Ginder GD, Lloyd JA. In Vitro Erythroid Differentiation and Lentiviral Knockdown in Human CD34+ Cells from Umbilical Cord Blood. Methods in Molecular Biology (Clifton, N.J.). 1698: 259-274. PMID 29076096 DOI: 10.1007/978-1-4939-7428-3_16 |
0.357 |
|
| 2017 |
Ginder GD, Williams DC. Readers of DNA methylation, the MBD family as potential therapeutic targets. Pharmacology & Therapeutics. PMID 29128342 DOI: 10.1016/J.Pharmthera.2017.11.002 |
0.589 |
|
| 2015 |
Sperlazza J, Rahmani M, Beckta J, Aust M, Hawkins E, Wang SZ, Zhu SZ, Podder S, Dumur C, Archer K, Grant S, Ginder GD. Depletion of the chromatin remodeler CHD4 sensitizes AML blasts to genotoxic agents and reduces tumor formation. Blood. PMID 26265695 DOI: 10.1182/Blood-2015-03-631606 |
0.358 |
|
| 2015 |
Desai MA, Webb HD, Sinanan LM, Scarsdale JN, Walavalkar NM, Ginder GD, Williams DC. An intrinsically disordered region of methyl-CpG binding domain protein 2 (MBD2) recruits the histone deacetylase core of the NuRD complex. Nucleic Acids Research. 43: 3100-13. PMID 25753662 DOI: 10.1093/Nar/Gkv168 |
0.519 |
|
| 2015 |
Ginder GD. Epigenetic regulation of fetal globin gene expression in adult erythroid cells. Translational Research : the Journal of Laboratory and Clinical Medicine. 165: 115-25. PMID 24880147 DOI: 10.1016/J.Trsl.2014.05.002 |
0.63 |
|
| 2015 |
Williams DC, Desai M, Ginder GD. A Fuzzy DNA Binding Region in MBD2 Recruits the Histone Deacetylase Core Complex of NuRD and Modifies Kinetics of DNA Binding Biophysical Journal. 108: 3-8. DOI: 10.1016/J.Bpj.2014.11.2125 |
0.488 |
|
| 2014 |
Cramer JM, Scarsdale JN, Walavalkar NM, Buchwald WA, Ginder GD, Williams DC. Probing the dynamic distribution of bound states for methylcytosine-binding domains on DNA. The Journal of Biological Chemistry. 289: 1294-302. PMID 24307175 DOI: 10.1074/Jbc.M113.512236 |
0.454 |
|
| 2013 |
Amaya M, Desai M, Gnanapragasam MN, Wang SZ, Zu Zhu S, Williams DC, Ginder GD. Mi2β-mediated silencing of the fetal γ-globin gene in adult erythroid cells. Blood. 121: 3493-501. PMID 23444401 DOI: 10.1182/Blood-2012-11-466227 |
0.809 |
|
| 2011 |
Mian OY, Wang SZ, Zhu SZ, Gnanapragasam MN, Graham L, Bear HD, Ginder GD. Methyl-binding domain protein 2-dependent proliferation and survival of breast cancer cells. Molecular Cancer Research : McR. 9: 1152-62. PMID 21693597 DOI: 10.1158/1541-7786.Mcr-11-0252 |
0.792 |
|
| 2011 |
Scarsdale JN, Webb HD, Ginder GD, Williams DC. Solution structure and dynamic analysis of chicken MBD2 methyl binding domain bound to a target-methylated DNA sequence. Nucleic Acids Research. 39: 6741-52. PMID 21531701 DOI: 10.1093/Nar/Gkr262 |
0.536 |
|
| 2011 |
Gnanapragasam MN, Scarsdale JN, Amaya ML, Webb HD, Desai MA, Walavalkar NM, Wang SZ, Zu Zhu S, Ginder GD, Williams DC. p66Alpha-MBD2 coiled-coil interaction and recruitment of Mi-2 are critical for globin gene silencing by the MBD2-NuRD complex. Proceedings of the National Academy of Sciences of the United States of America. 108: 7487-92. PMID 21490301 DOI: 10.1073/Pnas.1015341108 |
0.807 |
|
| 2011 |
Rupon JW, Wang SZ, Gnanapragasam M, Labropoulos S, Ginder GD. MBD2 contributes to developmental silencing of the human ε-globin gene. Blood Cells, Molecules & Diseases. 46: 212-9. PMID 21296012 DOI: 10.1016/J.Bcmd.2011.01.001 |
0.786 |
|
| 2011 |
Ginder GD. EV(I1)olution of AML DNA methylation. Blood. 117: 4-5. PMID 21212288 DOI: 10.1182/Blood-2010-10-311720 |
0.501 |
|
| 2011 |
Mian OY, Wang SZ, Zhu SZ, Bear HD, Ginder GD. Abstract 116: Methylcytosine binding domain protein 2(MBD2) dependent proliferation and survival of breast cancer cells Cancer Research. 71: 116-116. DOI: 10.1158/1538-7445.Am2011-116 |
0.544 |
|
| 2010 |
Ginder GD. Issues of gene regulation: DNA methylation. Science (New York, N.Y.). 228: 865-6. PMID 17815044 DOI: 10.1126/science.228.4701.865 |
0.481 |
|
| 2010 |
Mian O, Ginder G. Abstract 186: Methyl binding domain protien 2 (MBD2) promotes epithelial dedifferentiation in breast cancer Cancer Research. 70: 186-186. DOI: 10.1158/1538-7445.Am10-186 |
0.57 |
|
| 2009 |
Williams DC, Gnanapragasam MN, Webb HD, Scarsdale JN, Ginder GD. Targeting a Methyl Cytosine-Binding Protein Complex to Augment Fetal/Embryonic Globin Expression. Blood. 114: 974-974. DOI: 10.1182/Blood.V114.22.974.974 |
0.825 |
|
| 2008 |
Ginder GD, Gnanapragasam MN, Mian OY. The role of the epigenetic signal, DNA methylation, in gene regulation during erythroid development. Current Topics in Developmental Biology. 82: 85-116. PMID 18282518 DOI: 10.1016/S0070-2153(07)00004-X |
0.8 |
|
| 2008 |
Williams DC, Webb HD, Scarsdale JN, Ginder GD. Structural Analysis of a Methyl Cytosine-Binding Protein Complex That Regulates Expression of Fetal/Embryonic Globin Genes Blood. 112: 491-491. DOI: 10.1182/Blood.V112.11.491.491 |
0.611 |
|
| 2007 |
Ginder GD, Kransdorf EP, Rupon JW, Wang SZ, Zhu SZ, Gnanapragasam M, Lloyd J, Gaensler K. The role of methyl binding domain protein 2 (MBD2) in developmental globin gene regulation Blood Cells, Molecules, and Diseases. 38: 142-143. DOI: 10.1016/j.bcmd.2006.10.054 |
0.803 |
|
| 2006 |
Browne SK, Roesser JR, Zhu SZ, Ginder GD. Differential IFN-gamma stimulation of HLA-A gene expression through CRM-1-dependent nuclear RNA export. Journal of Immunology (Baltimore, Md. : 1950). 177: 8612-9. PMID 17142760 DOI: 10.4049/Jimmunol.177.12.8612 |
0.432 |
|
| 2006 |
Kransdorf EP, Wang SZ, Zhu SZ, Langston TB, Rupon JW, Ginder GD. MBD2 is a critical component of a methyl cytosine-binding protein complex isolated from primary erythroid cells. Blood. 108: 2836-45. PMID 16778143 DOI: 10.1182/Blood-2006-04-016394 |
0.835 |
|
| 2006 |
Rupon JW, Wang SZ, Gaensler K, Lloyd J, Ginder GD. Methyl binding domain protein 2 mediates gamma-globin gene silencing in adult human betaYAC transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 103: 6617-22. PMID 16608912 DOI: 10.1073/Pnas.0509322103 |
0.811 |
|
| 2005 |
Zhang P, Basu P, Redmond LC, Morris PE, Rupon JW, Ginder GD, Lloyd JA. A functional screen for Krüppel-like factors that regulate the human gamma-globin gene through the CACCC promoter element. Blood Cells, Molecules & Diseases. 35: 227-35. PMID 16023392 DOI: 10.1016/J.Bcmd.2005.04.009 |
0.782 |
|
| 2005 |
Rupon JW, Wang S, Gaensler K, Lloyd J, Ginder GD. Methyl Binding Domain Protein 2 Mediates gamma-Globin Silencing in Adult beta-YAC Transgenic Mice. Blood. 106: 3626-3626. DOI: 10.1182/Blood.V106.11.3626.3626 |
0.826 |
|
| 2004 |
Basu P, Sargent TG, Redmond LC, Aisenberg JC, Kransdorf EP, Wang SZ, Ginder GD, Lloyd JA. Evolutionary conservation of KLF transcription factors and functional conservation of human gamma-globin gene regulation in chicken. Genomics. 84: 311-9. PMID 15233995 DOI: 10.1016/J.Ygeno.2004.02.013 |
0.705 |
|
| 2004 |
Barrett DM, Gustafson KS, Wang J, Wang SZ, Ginder GD. A GATA factor mediates cell type-restricted induction of HLA-E gene transcription by gamma interferon. Molecular and Cellular Biology. 24: 6194-204. PMID 15226423 DOI: 10.1128/MCB.24.14.6194-6204.2004 |
0.316 |
|
| 2002 |
Singal R, Wang SZ, Sargent T, Zhu SZ, Ginder GD. Methylation of promoter proximal-transcribed sequences of an embryonic globin gene inhibits transcription in primary erythroid cells and promotes formation of a cell type-specific methyl cytosine binding complex. The Journal of Biological Chemistry. 277: 1897-905. PMID 11684679 DOI: 10.1074/jbc.M105580200 |
0.52 |
|
| 2001 |
Snyder SR, Waring JF, Zu Zhu S, Kaplan S, Schultz J, Ginder GD. A 3′-transcribed region of the HLA-A2 gene mediates posttranscriptional stimulation by IFN-γ Journal of Immunology. 166: 3966-3974. PMID 11238642 DOI: 10.4049/Jimmunol.166.6.3966 |
0.419 |
|
| 2001 |
Snyder SR, Wang J, Waring JF, Ginder GD. Identification of CCAAT Displacement Protein (CDP/cut) as a Locus-specific Repressor of Major Histocompatibility Complex Gene Expression in Human Tumor Cells Journal of Biological Chemistry. 276: 5323-5330. PMID 11084046 DOI: 10.1074/Jbc.M009454200 |
0.46 |
|
| 1999 |
Osborne CS, Pasceri P, Singal R, Sukonnik T, Ginder GD, Ellis J. Amelioration of retroviral vector silencing in locus control region beta-globin-transgenic mice and transduced F9 embryonic cells. Journal of Virology. 73: 5490-6. PMID 10364297 DOI: 10.1128/Jvi.73.7.5490-5496.1999 |
0.488 |
|
| 1998 |
Ginder GD, Singal R, Little JA, Dempsey N, Ferris R, Wang SZ. Silencing and activation of embryonic globin gene expression. Annals of the New York Academy of Sciences. 850: 70-9. PMID 9668529 DOI: 10.1111/J.1749-6632.1998.Tb10464.X |
0.766 |
|
| 1997 |
Singal R, Ferris R, Little JA, Wang SZ, Ginder GD. Methylation of the minimal promoter of an embryonic globin gene silences transcription in primary erythroid cells. Proceedings of the National Academy of Sciences of the United States of America. 94: 13724-9. PMID 9391093 DOI: 10.1073/Pnas.94.25.13724 |
0.776 |
|
| 1996 |
Gustafson KS, Ginder GD. Interferon-gamma induction of the human leukocyte antigen-E gene is mediated through binding of a complex containing STAT1alpha to a distinct interferon-gamma-responsive element. The Journal of Biological Chemistry. 271: 20035-46. PMID 8702722 DOI: 10.1074/Jbc.271.33.20035 |
0.452 |
|
| 1996 |
Wandersee NJ, Ferris RC, Ginder GD. Intronic and flanking sequences are required to silence enhancement of an embryonic beta-type globin gene. Molecular and Cellular Biology. 16: 236-46. PMID 8524301 DOI: 10.1128/MCB.16.1.236 |
0.373 |
|
| 1995 |
Sher GD, Ginder GD, Little J, Yang S, Dover GJ, Olivieri NF. Extended therapy with intravenous arginine butyrate in patients with beta-hemoglobinopathies. The New England Journal of Medicine. 332: 1606-10. PMID 7753139 DOI: 10.1056/Nejm199506153322404 |
0.574 |
|
| 1995 |
Waring JF, Radford JE, Burns LJ, Ginder GD. The human leukocyte antigen A2 interferon-stimulated response element consensus sequence binds a nuclear factor required for constitutive expression. The Journal of Biological Chemistry. 270: 12276-85. PMID 7744880 DOI: 10.1074/Jbc.270.20.12276 |
0.383 |
|
| 1995 |
Little JA, Dempsey NJ, Tuchman M, Ginder GD. Metabolic persistence of fetal hemoglobin. Blood. 85: 1712-8. PMID 7535584 DOI: 10.1182/Blood.V85.7.1712.Bloodjournal8571712 |
0.633 |
|
| 1993 |
Burns LJ, Waring JF, Reuter JJ, Stinski MF, Ginder GD. Only the HLA class I gene minimal promoter elements are required for transactivation by human cytomegalovirus immediate early genes Blood. 81: 1558-1566. PMID 8384027 DOI: 10.1182/Blood.V81.6.1558.1558 |
0.494 |
|
| 1993 |
Radford JE, Waring JF, Pohlman JK, Ginder GD. Stimulation of MHC class I transcription by interferon-gamma involves a non-A, non-C kinase in addition to protein kinase C. Journal of Interferon Research. 13: 133-41. PMID 8099599 DOI: 10.1089/Jir.1993.13.133 |
0.345 |
|
| 1993 |
Perrine SP, Ginder GD, Faller DV, Dover GH, Ikuta T, Witkowska HE, Cai SP, Vichinsky EP, Olivieri NF. A short-term trial of butyrate to stimulate fetal-globin-gene expression in the beta-globin disorders. The New England Journal of Medicine. 328: 81-6. PMID 7677966 DOI: 10.1056/Nejm199301143280202 |
0.39 |
|
| 1991 |
Radford JE, Chen E, Hromas R, Ginder GD. Cell-type specificity of interferon-gamma-mediated HLA class I gene transcription in human hematopoietic tumor cells. Blood. 77: 2008-15. PMID 1902124 |
0.342 |
|
| 1991 |
Glauber JG, Wandersee NJ, Little JA, Ginder GD. 5'-flanking sequences mediate butyrate stimulation of embryonic globin gene expression in adult erythroid cells. Molecular and Cellular Biology. 11: 4690-7. PMID 1875947 DOI: 10.1128/mcb.11.9.4690 |
0.726 |
|
| 1990 |
Brotherton TW, Reneker J, Ginder GD. Binding of HMG 17 to mononucleosomes of the avian beta-globin gene cluster in erythroid and non-erythroid cells. Nucleic Acids Research. 18: 2011-6. PMID 1692412 DOI: 10.1093/nar/18.8.2011 |
0.493 |
|
| 1989 |
Ginder GD, Burns LJ, Glauber JG, Beck J. Pharmacologic induction of embryonic globin gene expression in adult avian erythroid cells. Progress in Clinical and Biological Research. 316: 327-39. PMID 2482501 |
0.425 |
|
| 1988 |
Burns LJ, Glauber JG, Ginder GD. Butyrate induces selective transcriptional activation of a hypomethylated embryonic globin gene in adult erythroid cells. Blood. 72: 1536-42. PMID 2460154 |
0.456 |
|
| 1987 |
Chen E, Karr RW, Ginder GD. Negative and positive regulation of human leukocyte antigen class I gene transcription in K562 leukemia cells. Molecular and Cellular Biology. 7: 4572-5. PMID 2449606 DOI: 10.1128/mcb.7.12.4572 |
0.426 |
|
| 1987 |
Chen E, Karr RW, Frost JP, Gonwa TA, Ginder GD. Gamma interferon and 5-azacytidine cause transcriptional elevation of class I major histocompatibility complex gene expression in K562 leukemia cells in the absence of differentiation. Molecular and Cellular Biology. 6: 1698-705. PMID 2431285 DOI: 10.1128/MCB.6.5.1698 |
0.436 |
|
| 1987 |
Haugen T, Cripe T, Ginder G, Karin M, Turek L. Trans-activation of an upstream early gene promoter of bovine papilloma virus-1 by a product of the viral E2 gene. The Embo Journal. 6: 145-152. DOI: 10.1002/j.1460-2075.1987.tb04732.x |
0.305 |
|
| 1986 |
Brotherton TW, Ginder GD. Preferential in vitro binding of high mobility group proteins 14 and 17 to nucleosomes containing active and DNase I sensitive single-copy genes. Biochemistry. 25: 3447-54. PMID 3730369 DOI: 10.1021/bi00359a053 |
0.399 |
|
| 1984 |
Ginder GD, Whitters MJ, Pohlman JK. Activation of a chicken embryonic globin gene in adult erythroid cells by 5-azacytidine and sodium butyrate. Proceedings of the National Academy of Sciences of the United States of America. 81: 3954-8. PMID 6204332 DOI: 10.1073/pnas.81.13.3954 |
0.396 |
|
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